COc1cc2c(cc1Cc1ccccc1)C[C@H](N)C(=O)N2O CHEMBL2347110 Ki 1.6 nM
COc1cc2c(cc1Oc1ccccc1)C[C@H](N)C(=O)N2O CHEMBL2321943 Ki 1.66 nM
N[C@H]1Cc2cn(-c3ccccc3)nc2N(O)C1=O CHEMBL2347108 Ki 1.9 nM
COc1cccc(Oc2ccc3c(c2)CC(N)c2n[nH]c(=O)n2-3)c1 CHEMBL3220810 Ki 5.1 nM
N[C@H]1Cc2cc(Oc3ccccc3)ccc2N(O)C1=O CHEMBL2321944 Ki 7.1 nM
COc1ccc2c(c1)N(O)C(=O)[C@@H](N)C2 CHEMBL2049092 Ki 7.7 nM
COc1cccc(Cn2cc3c(n2)N(O)C(=O)[C@@H](N)C3)c1 CHEMBL3660154 IC50 8.93 nM
Cn1nc2c(c1Cc1ccccc1)C[C@H](N)C(=O)N2O CHEMBL3660149 IC50 11.5 nM
N[C@H]1Cc2c(cnn2Cc2ccccc2)N(O)C1=O CHEMBL2347115 Ki 12.0 nM
N[C@H]1Cc2ccccc2N(O)C1=O CHEMBL2047851 Ki 14.0 nM
NC1Cc2cc(Oc3ccccc3)ccc2-n2cnnc21 CHEMBL3220812 Ki 16.7 nM
COc1cccc(Cc2nn(C)c3c2C[C@H](N)C(=O)N3O)c1 CHEMBL2347113 Ki 22.0 nM
N[C@H]1Cc2cn(Cc3ccccc3)nc2N(O)C1=O CHEMBL2347107 Ki 23.0 nM
CCn1nc2c(c1Cc1ccccc1)C[C@H](N)C(=O)N2O CHEMBL3660163 IC50 24.3 nM
COc1ccc(Cn2cc3c(n2)N(O)C(=O)[C@@H](N)C3)cc1 CHEMBL3660157 IC50 28.3 nM
N[C@H]1Cc2ccc(Cl)cc2N(O)C1=O CHEMBL2047861 IC50 29.0 nM
N[C@H]1Cc2cc(C(F)(F)F)ccc2N(O)C1=O CHEMBL2049095 IC50 29.0 nM
Cc1ccc2c(c1)C[C@H](N)C(=O)N2O CHEMBL2049094 IC50 30.0 nM
N[C@H]1Cc2cn(-c3ccc(C(F)(F)F)cc3)nc2N(O)C1=O CHEMBL3660169 IC50 31.6 nM
Cn1nc(Cc2ccccc2)c2c1N(O)C(=O)[C@@H](N)C2 CHEMBL2347112 Ki 32.0 nM
N[C@H]1Cc2cc(Cl)ccc2N(O)C1=O CHEMBL2049093 IC50 36.0 nM
N[C@H]1Cc2cn(Cc3cccc4ccccc34)nc2N(O)C1=O CHEMBL3660151 IC50 36.0 nM
Cc1ccc2c(c1)N(O)C(=O)[C@@H](N)C2 CHEMBL2047862 IC50 37.0 nM
Cn1nc2c(c1Cc1ccc(C(F)(F)F)cc1)C[C@H](N)C(=O)N2O CHEMBL3660167 IC50 37.0 nM
N[C@H]1Cc2cn(-c3ccccc3C(F)(F)F)nc2N(O)C1=O CHEMBL3660168 IC50 38.8 nM
N[C@H]1Cc2cccc(F)c2N(O)C1=O CHEMBL2047856 IC50 40.0 nM
Cn1nc2c(c1Cc1ccccc1C(F)(F)F)C[C@H](N)C(=O)N2O CHEMBL3660166 IC50 40.7 nM
N[C@H]1Cc2nn(-c3ccccc3)cc2N(O)C1=O CHEMBL2347109 Ki 41.0 nM
Cn1nc2c(c1Cc1cccc(C(F)(F)F)c1)C[C@H](N)C(=O)N2O CHEMBL3660165 IC50 42.2 nM
N[C@H]1Cc2c(c(C(F)(F)F)nn2Cc2ccccc2)N(O)C1=O CHEMBL2347114 IC50 42.7 nM
N[C@H]1Cc2cn(Cc3ccc(OC(F)(F)F)cc3)nc2N(O)C1=O CHEMBL3660150 IC50 43.6 nM
N[C@H]1Cc2c(F)cccc2N(O)C1=O CHEMBL2049096 IC50 45.0 nM
COc1ccccc1Cn1cc2c(n1)N(O)C(=O)[C@@H](N)C2 CHEMBL3660153 IC50 50.2 nM
CC(C)n1nc2c(c1Cc1ccccc1)C[C@H](N)C(=O)N2O CHEMBL3660164 IC50 63.0 nM
Cn1nc2c(c1Cc1ccccc1)C[C@@H](N)C(=O)N2O CHEMBL3686862 IC50 63.7 nM
N[C@H]1Cc2cn(-c3cccc(C(F)(F)F)c3)nc2N(O)C1=O CHEMBL3660170 IC50 74.7 nM
N[C@H]1Cc2cn(C3CCC3)nc2N(O)C1=O CHEMBL3660160 IC50 81.3 nM
COc1cccc(Oc2ccc3c(c2)CC(N)c2nncn2-3)c1 CHEMBL3220811 Ki 81.5 nM
Cc1c2c(nn1Cc1ccccc1)N(O)C(=O)[C@@H](N)C2 CHEMBL3660155 IC50 81.6 nM
NC1Cc2cc(Oc3ccccc3)ccc2-n2c1n[nH]c2=O CHEMBL3220809 IC50 84.0 nM
NC1Cc2nn(-c3ccccc3)cc2N(O)C1=O CHEMBL3660158 IC50 85.0 nM
N[C@H]1Cc2cn(Cc3ccc4ccccc4c3)nc2N(O)C1=O CHEMBL3660152 IC50 117.0 nM
CC(C)n1cc2c(n1)N(O)C(=O)[C@@H](N)C2 CHEMBL3660161 IC50 153.0 nM
N[C@H]1Cc2cccc(C(F)(F)F)c2N(O)C1=O CHEMBL2047860 IC50 174.0 nM
COc1cccc2c1C[C@H](N)C(=O)N2O CHEMBL2049099 IC50 179.0 nM
N[C@H]1Cc2nn(Cc3ccccc3)cc2N(O)C1=O CHEMBL3660156 IC50 182.0 nM
N[C@@H]1Cc2ccccc2N(O)C1=O CHEMBL2047852 IC50 219.0 nM
N[C@H]1Cc2cccc(Cl)c2N(O)C1=O CHEMBL2047858 IC50 252.0 nM
O=C(O)C(Cc1ccccc1)N1C(=O)c2cc(Cl)c(Cl)cc2C1=O CHEMBL5429250 IC50 315.0 nM
Cc1cccc2c1C[C@H](N)C(=O)N2O CHEMBL2049098 IC50 319.0 nM
Cn1ncc2c1N(O)C(=O)[C@@H](N)C2 CHEMBL2347111 IC50 329.0 nM
N[C@H]1Cc2c(Cl)cccc2N(O)C1=O CHEMBL2049097 IC50 349.0 nM
COc1ccc(Cc2nn(C)c3c2C[C@H](N)C(=O)N3O)cc1 CHEMBL3660162 IC50 440.0 nM
COc1cccc2c1N(O)C(=O)[C@@H](N)C2 CHEMBL2047857 IC50 572.0 nM
Cn1c(CN2CCOCC2)nc2sc([C@H]3CCCN3C(=O)OCc3ccccc3)nc2c1=O CHEMBL5398073 IC50 610.0 nM
Cc1ccc(NC(=O)N2CCCC3(CCC(=O)N(CCC(C)C)C3)C2)cc1Cl CHEMBL4636981 IC50 810.0 nM
C[C@H]1COc2c(N3CCN(N)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 CHEMBL1215659 IC50 910.0 nM