CC(C)(C)OC(=O)N1CCN(C(=O)n2cc(-c3ccc(OC(F)(F)F)cc3)nn2)C(c2ccccc2)C1 CHEMBL5274434 IC50 2.0 nM
O=C(N1CCCC[C@@H]1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL3906477 IC50 2.5 nM
O=C(N1CCC=C[C@@H]1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4279328 IC50 2.5 nM
C#CCO[C@@H]1CC[C@H](Cc2ccccc2)N(C(=O)n2ncc(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)n2)C1 CHEMBL3895863 pIC50 2.512 nM
O=C(N1CCCC[C@@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4279884 pIC50 3.162 nM
O=C(N1C[C@H](O)C=C[C@@H]1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4287766 pIC50 3.162 nM
CC(C)(C)OC(=O)N1CCN(C(=O)n2cc(-c3ccc(OC(F)(F)F)cc3)nn2)C(Cc2ccccc2)C1 CHEMBL4581240 IC50 3.6 nM
O=C(N1C[C@H](O)C=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4289572 pIC50 5.012 nM
O=C(N1CCC=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc(Oc3ccccc3)cc2)nn1 CHEMBL4284689 pIC50 6.31 nM
O=C(N1C[C@@H](O)C=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4277989 pIC50 10.0 nM
O=C(N1CCC=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4281842 pIC50 12.59 nM
CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O CHEMBL175247 pIC50 13.18 nM
O=C(N1CCC=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc(Br)cc2)nn1 CHEMBL4294845 pIC50 15.85 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCP(=O)(F)OC CHEMBL113262 IC50 17.0 nM
O=C(N1CCCCC1Cc1ccccc1)n1ncc(C(O)(c2ccccc2)c2ccccc2)n1 CHEMBL3964338 pIC50 19.95 nM
O=C(N1CCCCC1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3970032 pIC50 25.12 nM
O=C(N1CCC=C[C@H]1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4291201 pIC50 25.12 nM
O=C(N1CCC=C[C@@H]1COCc1ccccc1)n1cc(-c2ccc([N+](=O)[O-])cc2)nn1 CHEMBL4281906 pIC50 31.62 nM
O=C(N1CCCCC1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL2144065 pIC50 39.81 nM
O=C(N1C[C@H](OCC2CC2)CC[C@@H]1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3897587 pIC50 39.81 nM
O=C(N1C[C@H](O)C=C[C@@H]1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3931744 pIC50 39.81 nM
O=C(N1CCCCC1Cc1ccccc1)n1cc(C(O)(c2ccccc2)c2ccccc2)nn1 CHEMBL3974512 pIC50 39.81 nM
CN(C(=O)Oc1nsnc1N1CCOCC1)C1CCCCCCC1 CHEMBL3613671 pIC50 43.65 nM
CN(C(=O)Oc1nsnc1N1CCOCC1)C1CCCCCC1 CHEMBL5284566 IC50 44.0 nM
CO[C@@H]1CC[C@H](Cc2ccccc2)N(C(=O)n2ncc(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)n2)C1 CHEMBL3913807 pIC50 50.12 nM
CN(Cc1cccc(-c2ccncc2)c1)C(=O)Oc1ccc(-c2ccc(C(N)=O)cc2)cc1 CHEMBL4068554 IC50 70.0 nM
Nc1cccc(Cn2nc(Oc3ccccc3)oc2=O)c1 CHEMBL3613162 IC50 73.0 nM
Cn1ncc2cc(C(c3ccc4c(cnn4C)c3)N3CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC3)ccc21 CHEMBL4469632 IC50 91.0 nM
CS(=O)(=O)c1ccc(CN2CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC2)c(N2CCCC2)c1 CHEMBL4436074 IC50 99.0 nM
O=C(N1CCC=C[C@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4289712 pIC50 100.0 nM
CO[C@H]1CC[C@H](Cc2ccccc2)N(C(=O)n2ncc(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)n2)C1 CHEMBL3922787 pIC50 125.89 nM
O=c1oc(Oc2ccccc2)nn1Cc1cccc([N+](=O)[O-])c1 CHEMBL3613161 IC50 130.0 nM
Cn1cc(CN2CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC2)c(-c2ccccc2)n1 CHEMBL3979183 IC50 130.0 nM
O=C(N1C[C@H](O)CC[C@@H]1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3912754 pIC50 158.49 nM
COc1cccc(CC2CCCCN2C(=O)n2ncc(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)n2)c1 CHEMBL3941507 pIC50 158.49 nM
O=C(N1CCCCC1COc1ccccc1)n1ncc(C(O)(c2ccccc2)c2ccccc2)n1 CHEMBL3897762 pIC50 158.49 nM
O=C(N1CCC=C[C@@H]1COCc1ccccc1)n1cc(-c2ccccc2)nn1 CHEMBL4288486 pIC50 158.49 nM
Cn1cc(CN2CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC2)c(-c2ccccc2Cl)n1 CHEMBL3894067 IC50 170.0 nM
O=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(C(c2cccnc2)c2cccnc2)CC1 CHEMBL3910417 IC50 182.0 nM
O=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(Cc2ccc(Cl)cc2)CC1 CHEMBL4584757 IC50 190.0 nM
O=C(N1C[C@@H](O)CC[C@@H]1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3983619 pIC50 199.53 nM
O=C(N1CCCCC1COc1ccc(F)cc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3921538 pIC50 199.53 nM
O=C(N1CCCCC1COc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3916842 pIC50 199.53 nM
COc1nn(Cc2cccc(N)c2)c(=O)o1 CHEMBL3613003 IC50 216.0 nM
O=C(N1C[C@@H](O)C=C[C@@H]1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 CHEMBL3904310 pIC50 251.19 nM
COc1ccc(CC2CCCCN2C(=O)n2ncc(C(O)(c3ccc(F)cc3)c3ccc(F)cc3)n2)cc1 CHEMBL3903742 pIC50 251.19 nM
O=C(N1CCCCC1COc1ccc(F)cc1)n1ncc(C(O)(c2ccccc2)c2ccccc2)n1 CHEMBL3986579 pIC50 251.19 nM
O=C(N1CC=C[C@@H](O)[C@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4277826 pIC50 251.19 nM
O=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(Cc2ccc(C(F)(F)F)cc2N2CCCC2)CC1 CHEMBL3945728 IC50 253.0 nM
Cn1nc(-c2ccccc2)cc1CN1CCN(C(=O)OC(C(F)(F)F)C(F)(F)F)CC1 CHEMBL3941394 IC50 290.0 nM
O=C(N1C[C@H](O)C=C[C@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4290942 pIC50 316.23 nM
CN(Cc1cccc(-c2ccncc2)c1)C(=O)Oc1ccc(-c2ccccc2)cc1 CHEMBL5269646 IC50 350.0 nM
COC(=O)c1cccc(Cn2nc(OC)oc2=O)c1 CHEMBL3613666 pIC50 446.68 nM
Cc1c(Br)cnc(OCc2ccc(F)cc2)c1C(=O)NC1CCCCCC1 CHEMBL4174442 IC50 530.0 nM
COc1ccc(-c2cc(C(=O)NC3CCCCCC3)c(=O)n(Cc3ccc(F)cc3)c2C)cc1 CHEMBL4781965 IC50 530.0 nM
COc1ccc(-c2cc(C(=O)NC3CCCCCC3)c(OCc3ccc(F)cc3)nc2C)cc1 CHEMBL4753784 IC50 530.0 nM
O=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(Cc2ccc(C(F)(F)F)cc2N2CC[C@@H](O)C2)CC1 CHEMBL4437377 IC50 540.0 nM
O=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(Cc2ccc(Cl)cc2N2CC[C@H]3CCCN3C2)CC1 CHEMBL4435014 IC50 562.0 nM
O=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(C(c2cocn2)c2cocn2)CC1 CHEMBL3986768 IC50 600.0 nM
O=C(N1CCCC[C@H]1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL3934441 pIC50 630.96 nM
O=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(Cc2ccc(Cl)cc2N2CCN(CCF)CC2)CC1 CHEMBL4468639 IC50 660.0 nM
O=C(N1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1)n1cncn1 CHEMBL3402827 IC50 750.0 nM
O=C(N1CC=C[C@@H](O)[C@@H]1COCc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL4278232 pIC50 794.33 nM
CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)Cc3ccc(Oc4ccccc4)cc3)ccc2O1 CHEMBL3319620 Ki 800.0 nM
COc1nn(Cc2cccc(C(F)(F)F)c2)c(=O)o1 CHEMBL3613668 IC50 870.0 nM
O=C(OC(C(F)(F)F)C(F)(F)F)N1CCN(Cc2ccc(C(F)(F)F)cc2N2CC[C@H](O)C2)CC1 CHEMBL4522687 IC50 940.0 nM