Cn1cc(-c2cc3c(cn2)OC2(CCN(C(=O)c4ccc5[nH]c(-c6ccn(C)n6)nc5c4)CC2)CC3=O)cn1 CHEMBL1089882 IC50 0.21 nM
Cc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(-c4cnn(C)c4)ncc2O3)cc2cn[nH]c12 CHEMBL1089883 IC50 0.3 nM
COc1cc2c(cn1)OC1(CCN(C(=O)c3cc(C)c4[nH]ncc4c3)CC1)CC2=O CHEMBL1091996 IC50 0.31 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccc(NC5CCC5)nc4c3)CC1)C2 CHEMBL3699916 IC50 1.0 nM
CCCNc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2n1 CHEMBL2419600 IC50 1.1 nM
CNc1ccc2ccc(C(=O)N3CCC4(CC3)CC(=O)c3nn(C(C)(C)C)cc3C4)cc2n1 CHEMBL2323626 IC50 1.3 nM
CN(C)c1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2n1 CHEMBL2419589 IC50 1.5 nM
COc1ccccc1[C@H](Cn1c(=O)n(C(C)(C)C(=O)O)c(=O)c2c(C)c(-c3ncco3)sc21)OC1CCOCC1 CHEMBL3407547 IC50 1.7 nM
CNc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2n1 CHEMBL2419598 IC50 1.7 nM
CC(F)(F)CNc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2n1 CHEMBL3699930 IC50 1.7 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccc(NCC(F)(F)F)nc4c3)CC1)C2 CHEMBL3699929 IC50 1.72 nM
CCNc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2n1 CHEMBL3699918 IC50 1.8 nM
COc1ccc(C)c2[nH]c(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL3699881 IC50 1.9 nM
CCOc1nc2ccc(Oc3ccc(/C=C/[C@H](C)NC(C)=O)cn3)c(Cl)c2s1 CHEMBL4225405 IC50 1.9 nM
COc1ccc2ncc(C(=O)N3CCC4(CC3)CC(=O)c3c(cnn3C(C)C)C4)cc2c1 CHEMBL2323628 IC50 2.1 nM
CC1=CC(C(=O)N2CCC3(CC2)Cc2cn(C(C)(C)C)nc2C(=O)N3)=CC2C(C)=NNC12 CHEMBL3699871 IC50 2.1 nM
Cc1cc(C(=O)N2CCC3(CC2)Cc2cn(C(C)(C)C)nc2C(=O)N3)cc2c(Cl)n[nH]c12 CHEMBL3699886 IC50 2.1 nM
COc1cc(C(=O)N2CCC3(CC2)Cc2cn(C(C)(C)C)nc2C(=O)N3)cc2c(C)n[nH]c12 CHEMBL3699903 IC50 2.1 nM
CC(=O)N[C@@H](C)/C=C/c1ccc(Oc2ccc3nc(C(C)C)sc3c2F)nc1 CHEMBL4229067 IC50 2.1 nM
CC(C)Nc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2n1 CHEMBL3699914 IC50 2.2 nM
COc1cc(C(=O)N2CCC3(CC2)Cc2cn(C(C)(C)C)nc2C(=O)N3)cc2[nH]ncc12 CHEMBL3699889 IC50 2.4 nM
COc1cccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL3699893 IC50 2.4 nM
CCN(C)c1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2n1 CHEMBL3699915 IC50 2.4 nM
CCCNc1nccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL3699925 IC50 2.5 nM
COc1nccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL2419597 IC50 2.6 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccc(NC5CC5)nc4c3)CC1)C2 CHEMBL3699913 IC50 2.6 nM
CC1=CC(C(=O)N2CCC3(CC2)Cc2cn(CC(C)(C)O)nc2C(=O)N3)=CC2C(C)=NNC12 CHEMBL3699873 IC50 2.7 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccnc(NC5CCC5)c4c3)CC1)C2 CHEMBL3699924 IC50 2.7 nM
CCNc1nccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL3699927 IC50 2.7 nM
CC(C)n1ncc2c1C(=O)CC1(CCN(C(=O)c3ccc4[nH]c(C(N)=O)cc4c3)CC1)C2 CHEMBL2323629 IC50 2.9 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccnc(NC5CC5)c4c3)CC1)C2 CHEMBL3699921 IC50 2.9 nM
CC(=O)N[C@@H](C)c1cc(-c2cnc(Oc3ccc(OC(C)C)cc3)s2)no1 CHEMBL221169 IC50 3.0 nM
CO[C@H]1CCCC[C@@H](c2ccccc2)OC(=O)[C@@H](C)[C@@]2(O)O[C@H]([C@@H](C)[C@H](O)[C@H]2OC)[C@@H](C)/C=C/[C@H]1OC(=O)CCC1=[N+]2C(=Cc3c(C)cc(C)n3[B-]2(F)F)C=C1 CHEMBL540678 Kd(app) 3.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4c(Cl)c[nH]c4c3)CC1)C2 CHEMBL2419593 IC50 3.0 nM
COc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(-c4cncc(C(=O)O)c4)ccc2O3)cc2c1c(C)cn2C1CC1 CHEMBL4557289 IC50 3.0 nM
COc1cccc2ncc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL3699896 IC50 3.2 nM
COCCNc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2n1 CHEMBL3699917 IC50 3.3 nM
COc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2c1 CHEMBL3699875 IC50 3.8 nM
CCCOc1ccc(Oc2ncc(C#CC(C)NC(C)=O)s2)cc1 CHEMBL223100 IC50 4.0 nM
COc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2n1 CHEMBL2419596 IC50 4.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4[nH]nc(Cl)c4c3)CC1)C2 CHEMBL2419591 IC50 4.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3cnc4c(Cl)c[nH]c4c3)CC1)C2 CHEMBL2419594 IC50 4.2 nM
CC(=O)N[C@@H](C)/C=C/c1ccc(Oc2ccc3nc(C(C)C)sc3c2Cl)nc1 CHEMBL4225659 IC50 4.3 nM
CNC(=O)Nc1sc2nc(C)ccc2c1C(=O)N1CCC(N2CCC[C@@]3(C2)CC(C)(C)OC3=O)CC1 CHEMBL2030573 IC50 4.4 nM
COc1cc(C(=O)N2CCC3(CC2)Cc2cn(C(C)(C)C)nc2C(=O)N3)nc2c(OC)cccc12 CHEMBL3699877 IC50 4.4 nM
Cc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(-c4cc[nH]n4)ccc2O3)cc2cn[nH]c12 CHEMBL1090854 IC50 4.5 nM
Cc1cc(C(=O)N2CCC3(CC2)CC(=O)c2c(ccnc2OC(C)C)O3)cc2cn[nH]c12 CHEMBL1089181 IC50 4.5 nM
CCC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3cc(C)c4[nH]nc(C)c4c3)CC1)C2 CHEMBL2419607 IC50 4.5 nM
CC(C)Nc1nccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL3699922 IC50 4.7 nM
CCNC(=O)Nc1sc2c(OC)cccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCCN2C3=O)CC1 CHEMBL2059303 IC50 4.9 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC3CCCC3)cc2)s1 CHEMBL220563 IC50 5.0 nM
CC(C)n1ncc2c1C(=O)CC1(CCN(C(=O)c3cc(-c4ccc(C(=O)O)cc4)nc(N(C)C)c3)CC1)C2 CHEMBL4753907 pIC50 5.012 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCCCCN2C3=O)CC1 CHEMBL2059099 IC50 5.1 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4[nH]nc(C(N)=O)c4c3)CC1)C2 CHEMBL3699880 IC50 5.1 nM
COc1ccc2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc2c1 CHEMBL3699872 IC50 5.3 nM
COc1n[nH]c2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL3699901 IC50 5.3 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCC[C@@]3(C2)CC(C)(C)OC3=O)CC1 CHEMBL1910404 IC50 5.4 nM
CCOc1ccc(N2CCN(c3noc([C@H](C)NC(C)=O)n3)[C@@H](C)C2)c(C)c1 CHEMBL3110092 IC50 5.4 nM
CNc1cc2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc2cn1 CHEMBL3699895 IC50 5.5 nM
COc1cc(C(=O)N2CCC3(CC2)Cc2cn(C(C)(C)C)nc2C(=O)N3)cc2cn[nH]c12 CHEMBL3699825 IC50 5.6 nM
COc1cccc2c(C(=O)N3CCC(N4CCCC5(C4)C(=O)N4CCCCN4C5=O)CC3)c(NC(N)=O)sc12 CHEMBL2059301 IC50 5.9 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccc(N)nc4c3)CC1)C2 CHEMBL3699894 IC50 5.9 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4[nH]cc(Cl)c4c3)CC1)C2 CHEMBL2419592 IC50 5.9 nM
CC(=O)NC(C)C#Cc1ccc(Oc2ccc(OC(C)C)cc2)cc1 CHEMBL212460 IC50 6.0 nM
Cc1n[nH]c2c(C)cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL2419604 IC50 6.0 nM
CNc1nccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL2419599 IC50 6.0 nM
Cc1cc(C(=O)N2CCC3(CC2)CC(=O)c2cc(-c4ccn(C)n4)ccc2O3)cc2cn[nH]c12 CHEMBL1088893 IC50 6.1 nM
CNC(=O)Nc1sc2c(OC)cccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCCN2C3=O)CC1 CHEMBL2059302 IC50 6.1 nM
COCCNc1nccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL3699926 IC50 6.1 nM
CC(C)(C)Nc1nccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL3699830 IC50 6.3 nM
Cc1noc(C)c1-c1ccc2c(c1)C(=O)CC1(CCN(C(=O)c3cc(C)c4[nH]ncc4c3)CC1)O2 CHEMBL1089877 IC50 6.4 nM
COc1cccc2c1C(=O)CC1(CCN(C(=O)c3cc(C)c4[nH]ncc4c3)CC1)O2 CHEMBL1091589 IC50 6.5 nM
Cc1nc2c(C)cc(C(=O)N3CCC4(CC3)CC(=O)c3nn(C(C)(C)C)cc3O4)cc2[nH]1 CHEMBL1958374 IC50 6.6 nM
Cc1cc(C(=O)N2CCC3(CC2)CC(=O)c2nn(C(C)(C)C)cc2O3)cc2cn[nH]c12 CHEMBL1958360 IC50 6.9 nM
CC(=O)N[C@@H](C)/C=C/c1ccc(Oc2ccc(OCC3CC3)cc2Cl)nc1 CHEMBL4224858 IC50 6.9 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC3CC3)cc2)s1 CHEMBL376717 IC50 7.0 nM
CC(=O)NC(C)c1ccc(-c2ccc(Oc3ccc(Oc4ccccc4)cc3)cc2)cc1 CHEMBL567281 IC50 7.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3cnc4[nH]cc(Cl)c4c3)CC1)C2 CHEMBL3699911 IC50 7.1 nM
Cc1cc(C(=O)N2CCC3(CC2)CC(=O)c2nn(C(C)(C)C)cc2O3)cc2[nH]cnc12 CHEMBL1958373 IC50 7.4 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCCCN2C3=O)CC1 CHEMBL2059098 IC50 7.5 nM
COc1cccc2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc12 CHEMBL3699876 IC50 7.5 nM
Cc1cc(-c2ccc3c(c2)C(=O)CC2(CCN(C(=O)c4cc(C)c5[nH]ncc5c4)CC2)O3)n[nH]1 CHEMBL1088894 IC50 7.6 nM
CC(=O)NC(C)c1cc(-c2cnc(Oc3ccc(OC(C)C)cc3)s2)no1 CHEMBL220271 IC50 8.0 nM
CCCOc1ccc(Oc2ccc(-c3ccc([C@H](C)NC(C)=O)cc3)cn2)cc1 CHEMBL566024 IC50 8.0 nM
CCN1C(=O)C2(CCCN(C3CCN(C(=O)c4c(NC(=O)NC)sc5ccccc45)CC3)C2)C(=O)N1CC CHEMBL2059093 IC50 8.1 nM
CCOc1ccc(N2CCN(c3noc(C4(NC(C)=O)CCC4)n3)[C@@H](C)C2)c(C)c1 CHEMBL3110076 IC50 8.2 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4[nH]c(N)nc4c3)CC1)C2 CHEMBL3699898 IC50 8.4 nM
CNC(=O)Nc1sc2nc(C)ccc2c1C(=O)N1CCC(N2CCC[C@]3(CC(=O)N(C(C)C)C3=O)C2)CC1 CHEMBL2030575 IC50 8.5 nM
CNc1n[nH]c2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL3699908 IC50 8.6 nM
COc1cc(C(=O)N2CCC3(CC2)CC(=O)c2c(cnn2C(C)C)C3)cc(-c2ccc(C(=O)O)cc2)n1 CHEMBL4567446 IC50 8.66 nM
CNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCCCN2C3=O)CC1 CHEMBL2059097 IC50 8.7 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccnc(Cl)c4c3)CC1)C2 CHEMBL3699828 IC50 8.9 nM
CNC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC3CC3)cc2)s1 CHEMBL384907 IC50 9.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC(C)C)cc2C)s1 CHEMBL232004 IC50 9.0 nM
CCNC(=O)Nc1sc2nc(C)ccc2c1C(=O)N1CCC(N2CCC[C@]3(CCN(C(C)C)C3=O)C2)CC1 CHEMBL2030574 IC50 9.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(OC3CCN(c4ccc(OC[C@H]5CC5(F)F)cn4)C3)cc2)s1 CHEMBL3691052 IC50 9.0 nM
CNc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cnn(C(C)C)c3C(=O)N4)cc2n1 CHEMBL3699855 IC50 9.2 nM
COc1ccc2ncc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2c1 CHEMBL3699874 IC50 9.2 nM
CNc1cc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2cn1 CHEMBL3699910 IC50 9.2 nM
Cc1cc(C(=O)N2CCC3(CC2)CC(=O)c2nn(C4CCCC4)cc2O3)cc2cn[nH]c12 CHEMBL1958359 IC50 9.4 nM
CN(C)c1cc(C(=O)N2CCC3(CC2)CC(=O)c2nn(C(C)(C)C)cc2O3)cc(-c2ccc(C(=O)O)cc2)n1 CHEMBL4762472 IC50 9.4 nM
CCOc1ccc(N2CCN(c3noc(C(C)(C)NC(C)=O)n3)[C@@H](C)C2)c(C)c1 CHEMBL3110075 IC50 9.8 nM
CC(C)(C)n1cc2c(n1)C(=O)CC1(CCN(C(=O)c3ccc4[nH]ncc4c3)CC1)O2 CHEMBL2419601 IC50 9.8 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC(C)C)cc2)s1 CHEMBL375532 IC50 10.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC3CC3)cc2Cl)s1 CHEMBL233384 IC50 10.0 nM
CC(C)n1ncc2c1C(=O)CC1(CCN(C(=O)c3ccc4ccc(N)nc4c3)CC1)C2 CHEMBL2323627 IC50 10.0 nM
Cc1n[nH]c2c(C)cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4C)cc12 CHEMBL2419610 IC50 10.0 nM
CC1=CC(C(=O)N2CCC3(CC2)Cc2cn(C(C)(C)C)nc2C(=O)N3)=CC2C=NNC12 CHEMBL3699870 IC50 10.0 nM
CC(=O)N[C@@H](C)/C=C/c1ccc(Oc2ccc3nc(C(C)(C)O)sc3c2Cl)nc1 CHEMBL4224749 IC50 10.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(Oc3ccccc3)cc2)s1 CHEMBL376983 IC50 11.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC(C)C)cc2F)s1 CHEMBL233004 IC50 11.0 nM
COc1cccc2c1C(=O)CC1(CCN(C(=O)c3cc(C)c4[nH]nc(C)c4c3)CC1)O2 CHEMBL1092308 IC50 11.0 nM
CNC(=O)c1cc2cc(C(=O)N3CCC4(CC3)CC(=O)c3c(OC)cccc3O4)ccc2[nH]1 CHEMBL1089529 IC50 11.0 nM
CC(C)(C)n1cc2c(n1)C(=O)CC1(CCN(C(=O)c3ccc4[nH]cnc4c3)CC1)O2 CHEMBL1955896 IC50 11.0 nM
CC1=CC(C(=O)N2CCC3(CC2)Cc2cn(C(C)C)nc2C(=O)N3)=CC2C(C)=NNC12 CHEMBL3699869 IC50 11.0 nM
CNc1nc2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc2[nH]1 CHEMBL3699897 IC50 11.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC(C)C)cc2Cl)s1 CHEMBL395345 IC50 12.0 nM
CCCOc1cccc(Oc2ccc(-c3ccc(C(C)NC(C)=O)cc3)cc2)c1 CHEMBL567291 IC50 12.0 nM
COc1cccc2c1C(=O)CC1(CCN(C(=O)c3ccc4[nH]c(-c5ccccn5)nc4c3)CC1)O2 CHEMBL1088921 IC50 12.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4nc(N)ccc4c3)CC1)C2 CHEMBL3699882 IC50 12.0 nM
COc1cc2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc2cn1 CHEMBL2419595 IC50 12.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2CCc3cc(OCC4CC4)ccc3C2)cc1 CHEMBL3953449 IC50 12.0 nM
COc1cc(C(=O)N2CCC3(CC2)CC(=O)c2nn(C(C)(C)C)cc2O3)cc(-c2ccc(C(=O)O)cc2)n1 CHEMBL4743101 pIC50 12.59 nM
CC(=O)NC(C)C#Cc1cnc(Oc2cccc(OCC(C)C)c2)s1 CHEMBL220230 IC50 13.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC3CCCC3)cc2)s1 CHEMBL221262 IC50 13.0 nM
CCCOc1ccc(Oc2ncc(C#CC(C)NC(C)=O)s2)c(Cl)c1 CHEMBL233383 IC50 13.0 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1 CHEMBL1910400 IC50 13.0 nM
CCn1nc2c(c1C)OC1(CCN(C(=O)c3cc(C)c4[nH]nc(C)c4c3)CC1)CC2=O CHEMBL1958362 IC50 13.0 nM
CCOc1ccc(N2CCN(c3noc([C@@H](C)NC(C)=O)n3)[C@@H](C)C2)c(C)c1 CHEMBL3110093 IC50 13.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4c(C#N)n[nH]c4c3)CC1)C2 CHEMBL3699879 IC50 13.0 nM
Cc1n[nH]c2c(C)cc(C(=O)N3CCC4(CC3)Cc3cn(C5CCC5)nc3C(=O)N4)cc12 CHEMBL2419606 IC50 13.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4[nH]nc(N)c4c3)CC1)C2 CHEMBL3699885 IC50 13.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3[C@@H](F)C2)cc1 CHEMBL3982455 IC50 13.0 nM
CC(=O)N[C@@H](C)/C=C/c1cnc(Oc2ccc(OCC3CC3)cc2Cl)s1 CHEMBL4226229 IC50 13.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2cccc(OC(C)C)c2)s1 CHEMBL220031 IC50 14.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(NCC3CC3)c(Cl)c2)s1 CHEMBL220321 IC50 14.0 nM
CCCOc1ccc(Oc2ccc(-c3ccc(C(C)NC(C)=O)cc3)cc2)cc1 CHEMBL567935 IC50 14.0 nM
Cc1cc(C(=O)N2CCC3(CC2)CC(=O)c2nn(C4CCC4)cc2O3)cc2cn[nH]c12 CHEMBL1958358 IC50 14.0 nM
Cc1n[nH]c2c(C)cc(C(=O)N3CCC4(CC3)CC(=O)c3nn(C(C)C)cc3O4)cc12 CHEMBL1958371 IC50 14.0 nM
CCNC(=O)Nc1sc2nc(C)ccc2c1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1 CHEMBL2030570 IC50 14.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4cnc(N)cc4c3)CC1)C2 CHEMBL3699883 IC50 14.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4[nH]nc(C#N)c4c3)CC1)C2 CHEMBL3699884 IC50 14.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC(C)C)nc2)s1 CHEMBL208680 IC50 15.0 nM
CC(=O)N[C@@H](C)CC[C@H]1CC[C@H](Oc2ccc(OC(C)C)nc2)CC1 CHEMBL1630721 IC50 15.0 nM
CC1(C)CC2(CCCN(C3CCN(C(=O)c4c(NC(N)=O)sc5ccccc45)CC3)C2)C(=O)O1 CHEMBL1910398 IC50 15.0 nM
CNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1 CHEMBL1910399 IC50 15.0 nM
CCNC(=O)Nc1sc2nc(C)ccc2c1C(=O)N1CCC(N2CCCC3(C2)OC(=O)N(C(C)C)C3=O)CC1 CHEMBL2030576 IC50 15.0 nM
CCNC(=O)Nc1sc2nc(C)ccc2c1C(=O)N1CCC(N2CCCC3(C2)N=C(C)N(C(C)C)C3=O)CC1 CHEMBL2030577 IC50 15.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC3CCCCC3)cc2)s1 CHEMBL220668 IC50 16.0 nM
CC(=O)NC(C)c1ccc(-c2ccc(Oc3cccc(Oc4ccccc4)c3)cc2)cc1 CHEMBL585885 IC50 16.0 nM
COc1cccc2c1C(=O)CC1(CCN(C(=O)c3ccc4[nH]c(C(N)=O)nc4c3)CC1)O2 CHEMBL1091186 IC50 16.0 nM
COc1cccc2c1C(=O)CC1(CCN(C(=O)c3cc(C)c4[nH]c(C(N)=O)cc4c3)CC1)O2 CHEMBL1090862 IC50 16.0 nM
COc1cccc2c1C(=O)CC1(CCN(C(=O)c3ccc4[nH]c(-c5ccccc5)nc4c3)CC1)O2 CHEMBL1090863 IC50 16.0 nM
CCNC(=O)Nc1sc2ncccc2c1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1 CHEMBL2030569 IC50 16.0 nM
CC(=O)N[C@@H](C)c1nc(-c2ccc(Oc3ccc(Oc4ccccc4)cc3)cc2)no1 CHEMBL3965346 IC50 16.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccc(Cl)nc4c3)CC1)C2 CHEMBL3699829 IC50 16.0 nM
C[C@H](NC(=O)c1cn[nH]c1)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3918839 IC50 16.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2Cc3ccc(OCC4CC4(F)F)cc3C(F)C2)cc1 CHEMBL3968391 IC50 16.0 nM
CCN1C(=O)C2(CCCN(C3CCN(C(=O)c4c(NC(N)=O)sc5ccccc45)CC3)C2)N=C1C(C)C CHEMBL2030564 IC50 17.0 nM
CCNC(=O)Nc1sc2nc(C)ccc2c1C(=O)N1CCC(N2CCCC3(C2)NC(=O)N(C(C)C)C3=O)CC1 CHEMBL2030578 IC50 17.0 nM
CC(C)(C)n1ncc2c1C(=O)CC1(CCN(C(=O)c3ccc4[nH]ncc4c3)CC1)C2 CHEMBL3359261 IC50 17.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4cn[nH]c4c3)CC1)C2 CHEMBL3699878 IC50 17.0 nM
C[C@H](NC(=O)c1cncs1)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3898944 IC50 17.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(CN2Cc3ccc(OCC4CC4(F)F)cc3C(F)C2)cc1 CHEMBL3943745 IC50 17.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2cccc(OCC(C)C)c2C)s1 CHEMBL393254 IC50 18.0 nM
CCCOc1ccc(Oc2ccc(-c3ccc(C(C)NC(C)=O)cc3)cn2)cc1 CHEMBL585578 IC50 18.0 nM
CCOc1cc(C(=O)N2CCC3(CC2)CC(=O)c2nn(CC)c(C)c2O3)cc2c(CC)n[nH]c12 CHEMBL1958366 IC50 18.0 nM
CNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(CCN(C(C)C)C3=O)C2)CC1 CHEMBL2030568 IC50 18.0 nM
Cc1[nH]nc2c(C)cc(C(=O)N3CCC4(CC3)Cc3cnn(C(C)(C)C)c3C(=O)N4)cc12 CHEMBL2419608 IC50 18.0 nM
COc1n[nH]c2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc12 CHEMBL3699900 IC50 18.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 CHEMBL377212 IC50 19.0 nM
COc1cccc2c1C(=O)CC1(CCN(C(=O)c3ccc4[nH]c(-c5cccnc5)nc4c3)CC1)O2 CHEMBL1092605 IC50 19.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4[nH]nc(C(F)(F)F)c4c3)CC1)C2 CHEMBL2419590 IC50 19.0 nM
Cc1n[nH]c2c(C)cc(C(=O)N3CCC4(CC3)Cc3cnn(C(C)C)c3C(=O)N4)cc12 CHEMBL2419609 IC50 19.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4c(C(F)(F)F)n[nH]c4c3)CC1)C2 CHEMBL3639987 IC50 19.0 nM
Cc1n[nH]c2c(C)cc(C(=O)N3CCC4(CC3)CC(=O)c3c(ccnc3OC(C)C)O4)cc12 CHEMBL1090200 IC50 20.0 nM
Cc1n[nH]c2c(C)cc(C(=O)N3CCC4(CC3)CC(=O)c3nn(C5CCOC5)c(C)c3O4)cc12 CHEMBL1958372 IC50 20.0 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N(C)N(C)C3=O)CC1 CHEMBL2059092 IC50 20.0 nM
COCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(OC3CCN(c4ccc(OCC5CC5)cc4)C3)cc2)s1 CHEMBL3926720 IC50 20.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3893801 IC50 20.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3927157 IC50 20.0 nM
CC(=O)NC(C)c1ccc(Oc2ccc(Oc3cccc(OCC4CC4)c3)cc2)cc1 CHEMBL4746516 IC50 20.0 nM
Cn1ncc2ccc(C(=O)N3CCC4(CC3)CC(=O)c3nn(C(C)(C)C)cc3O4)cc21 CHEMBL1955895 IC50 21.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccnc(N)c4c3)CC1)C2 CHEMBL3699826 IC50 21.0 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)NC(=O)N(CC)C3=O)CC1 CHEMBL2030410 IC50 22.0 nM
CCC(=O)N[C@@H](C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3920763 IC50 22.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3975236 IC50 22.0 nM
CC(=O)N1CCC(C(=O)N2CCC(N3CCN(C(=O)c4cc(-c5ccc(C)cc5)nc(-c5ccc(C)cc5)c4)CC3)CC2)CC1 CHEMBL1076223 IC50 23.0 nM
Cc1cc(C(=O)N2CCC3(CC2)CC(=O)c2nn(C(C)C)cc2O3)cc2cn[nH]c12 CHEMBL1958356 IC50 23.0 nM
CCN1C(=O)CC2(CCCN(C3CCN(C(=O)c4c(NC(N)=O)sc5ccccc45)CC3)C2)C1=O CHEMBL2030406 IC50 23.0 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCCN2C3=O)CC1 CHEMBL2059096 IC50 23.0 nM
CC(C)n1ncc2c1C(=O)CC1(CCN(C(=O)c3cnc4cc[nH]c4c3)CC1)C2 CHEMBL3359264 IC50 23.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCC(F)(F)C4)c3F)C2)cc1 CHEMBL3686602 IC50 23.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4cc(N)ncc4c3)CC1)C2 CHEMBL3699909 IC50 23.0 nM
CCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(OC3CCN(c4ccc(OCC5CC5)cc4)C3)cc2)s1 CHEMBL3982195 IC50 23.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCC5(CC5)C4)c3F)C2)cc1 CHEMBL3686596 IC50 24.0 nM
C[C@H](NC(=O)c1cnn(C)c1Cl)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3686709 IC50 24.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(CN2CCc3cc(OC[C@H]4CC4(F)F)ccc3C2)cc1 CHEMBL3979411 IC50 24.0 nM
C[C@H](NC(=O)C1(C)CC1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3981111 IC50 24.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(OC3CCN(c4ccc(OCC5CC5(F)F)cn4)C3)cc2)s1 CHEMBL3686642 IC50 25.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cc3)C2)cc1 CHEMBL3940154 IC50 25.0 nM
C[C@H](NC(=O)c1cn[nH]c1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3970596 IC50 25.0 nM
C[C@H](NC(=O)C(F)F)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3977323 IC50 25.0 nM
CC(=O)N[C@@H](C)/C=C/c1cnc(Oc2ccc(OCC3CC3)cc2Cl)cn1 CHEMBL4226182 IC50 25.0 nM
CC(C#Cc1cnc(Oc2ccc(Oc3ccccc3)cc2)s1)NC(N)=O CHEMBL208672 IC50 26.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2cccc(OC3CCCCC3)c2)s1 CHEMBL375116 IC50 26.0 nM
COC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC3CC3)cc2)s1 CHEMBL222464 IC50 26.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(NCC4CC4)c3Cl)C2)cc1 CHEMBL3686630 IC50 26.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4c(N)nccc4c3)CC1)C2 CHEMBL3699827 IC50 26.0 nM
CCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(CN3Cc4ccc(OCC5CC5)cc4C(F)C3)cc2)s1 CHEMBL3954989 IC50 26.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3889763 IC50 26.0 nM
CC(=O)N[C@@H](C)/C=C/c1ccc(Oc2ccc3nc(C)sc3c2Cl)nc1 CHEMBL4225924 IC50 26.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC3CCCCC3)cc2)s1 CHEMBL219948 IC50 27.0 nM
CCOc1cc(C(=O)N2CCC3(CC2)CC(=O)c2nn(CC)c(C)c2O3)cc2c(C)n[nH]c12 CHEMBL1958365 IC50 27.0 nM
CCNC(=O)Nc1sc2cccnc2c1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1 CHEMBL2030571 IC50 27.0 nM
CC(=O)NC(C)c1cnc(-c2cnc(Oc3ccc(OC(C)C)cc3)s2)s1 CHEMBL219902 IC50 28.0 nM
CNc1cccc2ccc(C(=O)N3CCC4(CC3)Cc3cnn(C(C)C)c3C(=O)N4)cc12 CHEMBL3699862 IC50 28.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ncccc4c3)CC1)C2 CHEMBL3699887 IC50 28.0 nM
CNc1ccc2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc2n1 CHEMBL3699892 IC50 28.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(CN3CCc4cc(OCC5CC5(F)F)ccc4C3)cc2)s1 CHEMBL3939481 IC50 28.0 nM
C[C@H](NC(=O)c1cncs1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3980217 IC50 28.0 nM
C[C@H](NC(=O)[C@H]1C[C@H](F)C1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3908284 IC50 28.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC3CCCCC3)cc2Cl)s1 CHEMBL233006 IC50 29.0 nM
CCn1nc2c(c1C)OC1(CCN(C(=O)c3cc(C)c4[nH]cc(C)c4c3)CC1)CC2=O CHEMBL1958368 IC50 29.0 nM
Cc1n[nH]c2c(C)cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)C)nc3C(=O)N4)cc12 CHEMBL2419605 IC50 29.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ncc(OCC4CC4(F)F)cc3Cl)C2)cc1 CHEMBL3686569 IC50 29.0 nM
CC1=CC(C(=O)N2CCC3(CC2)Cc2cn(C(C)C)nc2C(=O)N3)=CC2C=NNC12 CHEMBL3699868 IC50 29.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(CN2Cc3ccc(OCC4CC4(F)F)cc3C(F)C2)cc1 CHEMBL3904426 IC50 29.0 nM
C[C@H](NC(=O)C(C)(F)F)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3901394 IC50 29.0 nM
CNC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 CHEMBL208944 IC50 30.0 nM
Cc1nc(-c2ccc3c(c2)C(=O)CC2(CCN(C(=O)c4cc(C)c5[nH]ncc5c4)CC2)O3)co1 CHEMBL1090193 IC50 30.0 nM
CC(=O)N[C@@H](C)CCc1ccc(Oc2ccc(OC(C)C)nc2)cc1 CHEMBL1630715 IC50 30.0 nM
CC(C)n1ncc2c1C(=O)CC1(CCN(C(=O)c3ccc4[nH]ncc4c3)CC1)C2 CHEMBL3359262 IC50 30.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3cc(OCC(C)C)ncc3F)C2)cc1 CHEMBL3686567 IC50 30.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC(C)(C)C)c3)C2)cc1 CHEMBL3691172 IC50 30.0 nM
CCCN(C)c1ncc(F)c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)n1 CHEMBL3662339 IC50 30.0 nM
COc1nccc2ccc(C(=O)N3CCC4(CC3)Cc3cnn(C(C)C)c3C(=O)N4)cc12 CHEMBL3699856 IC50 30.0 nM
C[C@H](NC(=O)c1cnco1)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3960462 IC50 30.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2Cc3ccc(OC(C)C)cc3C(F)C2)cc1 CHEMBL3953707 IC50 30.0 nM
COc1c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)ccnc1OCC1CC1 CHEMBL3686619 IC50 31.0 nM
COc1cc(C(=O)N2CCC3(CC2)Cc2cnn(C(C)C)c2C(=O)N3)cc2c(OC)cccc12 CHEMBL3699843 IC50 31.0 nM
COc1cc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2cn1 CHEMBL3699905 IC50 31.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(CN2CCc3cc(OC[C@@H]4CC4(F)F)ccc3C2)cc1 CHEMBL3923858 IC50 31.0 nM
CC(=O)N[C@@H](C)/C=C/c1cnc(Oc2ccc(OCC3CC3)cc2)s1 CHEMBL4225397 IC50 31.0 nM
CC(C)(C)n1cc2c(n1)C(=O)CC1(CCN(C(=O)c3ccc4[nH]nc(C(=O)O)c4c3)CC1)O2 CHEMBL4759617 pIC50 31.62 nM
CC(=O)NC(C)c1ccc(-c2ccc(Oc3cccc(Oc4ccccc4)c3)nc2)cc1 CHEMBL585491 IC50 32.0 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(CC(=O)N(CC)C3=O)C2)CC1 CHEMBL2030407 IC50 32.0 nM
COc1c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)ccnc1OCC(C)C CHEMBL3686612 IC50 32.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OC4CCCC4)c3Cl)C2)cc1 CHEMBL3662313 IC50 32.0 nM
CC(=O)NC(C)c1ccc(-c2ccc(Oc3ccc(OC(C)C)cc3)cc2)cc1 CHEMBL567936 IC50 33.0 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(CCN(CC)C3=O)C2)CC1 CHEMBL2030567 IC50 33.0 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCN2C3=O)CC1 CHEMBL2059094 IC50 33.0 nM
Cc1nc2ccc(C(=O)N3CCC4(CC3)CC(=O)c3c(cnn3C(C)C)C4)cc2[nH]1 CHEMBL3359265 IC50 33.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)CC4CC4)ncc3F)C2)cc1 CHEMBL3662335 IC50 33.0 nM
Cn1[nH]c2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc2c1=O CHEMBL3699902 IC50 33.0 nM
Cc1nocc1C(=O)N[C@@H](C)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3970293 IC50 33.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC3CCCCC3)cc2Cl)s1 CHEMBL393192 IC50 34.0 nM
O=C(c1c2ccccc2cc2ccccc12)N1CCC(N2CCC[C@@H](C(=O)N3CCOCC3)C2)CC1 CHEMBL208943 IC50 34.0 nM
CCC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(N4CCC(F)(F)C4)c3F)C2)cc1 CHEMBL3691122 IC50 34.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3cc(C(F)(F)F)c4[nH]ncc4c3)CC1)C2 CHEMBL3699899 IC50 34.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(CN3CCc4cc(OCC5CC5)ccc4C3)cc2)s1 CHEMBL3984243 IC50 34.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC(C)C)cc2Br)s1 CHEMBL233005 IC50 35.0 nM
CC(=O)NC(C)c1ccc(-c2ccc(Oc3ccc(OC(C)C)cc3)cc2C)cc1 CHEMBL565818 IC50 35.0 nM
CCCOc1ccc(Oc2ccc(-c3ccc(C(C)NC(=O)CCC)cc3)cn2)cc1 CHEMBL566862 IC50 35.0 nM
C[C@H](NC(=O)C(F)F)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 CHEMBL3686700 IC50 35.0 nM
Cc1cc(C(=O)N[C@@H](C)c2ccc(OC3CCN(c4cccc(C(F)(F)F)n4)C3)cc2)no1 CHEMBL3686701 IC50 35.0 nM
C[C@H](NC(=O)C(F)F)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3691043 IC50 35.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4(C)CC4)c3)C2)cc1 CHEMBL3691160 IC50 35.0 nM
CCCOc1cc(N2CC[C@@H](Oc3ccc([C@H](C)NC(=O)c4cncs4)cc3)C2)ccn1 CHEMBL3691205 IC50 35.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4CC4)c3Cl)C2)cc1 CHEMBL3691223 IC50 35.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCCC4)c3F)C2)cc1 CHEMBL3691245 IC50 35.0 nM
CCN(CC)c1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1F CHEMBL3691248 IC50 35.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OCC4CC4)c3F)C2)cc1 CHEMBL3658218 IC50 35.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OCC4CC4)c3Cl)C2)cc1 CHEMBL3658236 IC50 35.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OC4CCC4)c3F)C2)cc1 CHEMBL3662287 IC50 35.0 nM
C[C@H](NC(=O)CC#N)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3925942 IC50 35.0 nM
CNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCCN2C3=O)CC1 CHEMBL2059095 IC50 36.0 nM
CCCNc1nccc(N2CCC(Oc3ccc([C@H](C)NC(=O)N(C)C)cc3)C2)c1F CHEMBL3691125 IC50 36.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OC4CCC4)cc3)C2)cc1 CHEMBL3940409 IC50 36.0 nM
CCOc1ccc(Oc2ncc(C#CC(C)NC(C)=O)s2)cc1 CHEMBL223372 IC50 37.0 nM
CC(C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1)NC(N)=O CHEMBL247440 IC50 37.0 nM
CCn1nc2c(c1C)OC1(CCN(C(=O)c3cc(C)c4[nH]ncc4c3)CC1)CC2=O CHEMBL1958354 IC50 37.0 nM
CCc1cc(C(=O)N2CCC3(CC2)CC(=O)c2nn(CC)c(C)c2O3)cc2cn[nH]c12 CHEMBL1958364 IC50 37.0 nM
CCNC(=O)Nc1sc2nccnc2c1C(=O)N1CCC(N2CCCC3(C2)CC(C)(C)OC3=O)CC1 CHEMBL2030572 IC50 37.0 nM
CCOc1ccc(N2CCN(c3noc(CC)n3)[C@@H](C)C2)c(C)c1 CHEMBL3110081 IC50 37.0 nM
COc1c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)ccnc1OCCC1CC1 CHEMBL3686631 IC50 37.0 nM
COCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(OC3CCN(c4ccc(OCC5CC5(F)F)cn4)C3)cc2)s1 CHEMBL3691082 IC50 37.0 nM
CCN(CC(F)(F)F)c1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)n1 CHEMBL3662403 IC50 37.0 nM
COC1=CC(C(=O)N2CCC3(CC2)Cc2cnn(C(C)C)c2C(=O)N3)=CC2NN=CC12 CHEMBL3699838 IC50 37.0 nM
CCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(CN3CCc4cc(OCC5CC5(F)F)ccc4C3)cc2)s1 CHEMBL3914789 IC50 37.0 nM
CCC(=O)N[C@@H](C)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3893932 IC50 37.0 nM
COC(=O)N[C@@H](C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 CHEMBL378997 IC50 38.0 nM
Cc1noc(NC(C)C#Cc2cnc(Oc3ccc(Oc4ccccc4)cc3)s2)c1C CHEMBL397401 IC50 38.0 nM
CCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(O[C@@H]3CCN(c4ncnc(OCC5CC5)c4Cl)C3)cc2)s1 CHEMBL3662322 IC50 38.0 nM
Cc1cc(C(=O)N2CCC3(CC2)Cc2cnn(C(C)C)c2C(=O)N3)cc2c[nH]nc12 CHEMBL3699831 IC50 38.0 nM
C[C@H](NC(=O)C(F)F)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3900439 IC50 38.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)(F)C2)cc1 CHEMBL3943925 IC50 38.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(CN2CCc3cc(OCC4CC(F)(F)C4)ccc3C2)cc1 CHEMBL3971596 IC50 38.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(CN2CCc3cc(OCC4CCC4)ccc3C2)cc1 CHEMBL3892098 IC50 38.0 nM
C[C@H](NC(=O)C1CCC1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3915831 IC50 38.0 nM
CCC(=O)N[C@@H](C)c1ccc(CN2Cc3ccc(OCC4CC4(F)F)cc3C(F)C2)cc1 CHEMBL3937049 IC50 38.0 nM
Cc1ncc(-c2ccc3c(c2)C(=O)CC2(CCN(C(=O)c4cc(C)c5[nH]ncc5c4)CC2)O3)o1 CHEMBL1089547 IC50 39.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccc(OC[C@H]4CC4(F)F)cn3)C2)cc1 CHEMBL3686610 IC50 39.0 nM
COCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(OC3CCN(c4ccnc(OCC5CC5)c4)C3)cc2)s1 CHEMBL3691039 IC50 39.0 nM
COC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OC[C@H]4CC4(F)F)cn3)C2)cc1 CHEMBL3691111 IC50 39.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OC4CCC4)c3)C2)cc1 CHEMBL3691145 IC50 39.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(OC3CCN(c4ncnc(OCC5CC5)c4F)C3)cc2)s1 CHEMBL3658149 IC50 39.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OC4CCC4)c3Cl)C2)cc1 CHEMBL3662301 IC50 39.0 nM
COc1c(OCC2CC2)ncnc1N1CC[C@@H](Oc2ccc([C@H](C)NC(C)=O)cc2)C1 CHEMBL3662319 IC50 39.0 nM
C[C@H](NC(=O)C(F)(F)F)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3926880 IC50 39.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2C)cc1 CHEMBL3959032 IC50 39.0 nM
CCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(CN3CCc4cc(OCC5CC5)ccc4C3)cc2)s1 CHEMBL3911004 IC50 39.0 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)OC(=O)N(CC)C3=O)CC1 CHEMBL2030409 IC50 40.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CN(c3ccc(OCC4CC4(F)F)cc3F)C2)cc1 CHEMBL3659746 IC50 40.0 nM
C[C@H](NC(=O)c1cn[nH]c1)c1ccc(OC2CCN(c3ccc(OC[C@H]4CC4(F)F)cn3)C2)cc1 CHEMBL3691055 IC50 40.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OC4CCCCC4)c3)C2)cc1 CHEMBL3691151 IC50 40.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4CCC4)c3)C2)cc1 CHEMBL3691159 IC50 40.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OC4CCCC4)c3)C2)cc1 CHEMBL3691171 IC50 40.0 nM
CCCOc1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1F CHEMBL3691194 IC50 40.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4CC4(F)F)c3C)C2)cc1 CHEMBL3691201 IC50 40.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 CHEMBL3658164 IC50 40.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N4CCC5(CC5)C4)c3Cl)C2)cc1 CHEMBL3662436 IC50 40.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCCC(F)F)cc3)C2)cc1 CHEMBL3968452 IC50 40.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(OC3CCN(c4ccc(OCC5CC5)cc4)C3)cc2)s1 CHEMBL3897466 IC50 40.0 nM
CCC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3974818 IC50 40.0 nM
COc1c(OCC2CCC2)ccc2c1CCN(Cc1ccc([C@H](C)NC(C)=O)cc1)C2 CHEMBL3971420 IC50 40.0 nM
COc1c(OCCC2CC2)ccc2c1CCN(Cc1ccc([C@H](C)NC(C)=O)cc1)C2 CHEMBL3925665 IC50 40.0 nM
C[C@H](NC(=O)C1(C#N)CC1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3910036 IC50 40.0 nM
CC(=O)N[C@@H](C)/C=C/c1ccc(Oc2ccc3sc(C(C)C)nc3c2Cl)nc1 CHEMBL4228805 IC50 40.0 nM
CCCOc1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1OC CHEMBL3686613 IC50 41.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCC(F)(F)C4)c3Cl)C2)cc1 CHEMBL3686624 IC50 41.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC(C)C)c3)C2)cc1 CHEMBL3691146 IC50 41.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)C4CCC4)ncc3F)C2)cc1 CHEMBL3667052 IC50 41.0 nM
CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(c3ccc(OC4CCC4)cc3)C2)cc1 CHEMBL4111483 IC50 41.0 nM
COc1c(OCC2CCC2)ccc2c1CCN(Cc1ccc([C@H](C)NC(=O)C3CC3)cc1)C2 CHEMBL3931633 IC50 41.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC(C)C)cc2C#N)s1 CHEMBL232002 IC50 42.0 nM
CC(C#Cc1cnc(Oc2ccc(Oc3ccccc3)cc2)s1)Nc1ccon1 CHEMBL392598 IC50 42.0 nM
CCn1nc2c(c1C)OC1(CCN(C(=O)c3ccc4[nH]nc(C)c4c3)CC1)CC2=O CHEMBL1958361 IC50 42.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N(C)CC(F)F)c3F)C2)cc1 CHEMBL3686600 IC50 42.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4CC4)c3F)C2)cc1 CHEMBL3691192 IC50 42.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OCC4CC4(F)F)c3Cl)C2)cc1 CHEMBL3662300 IC50 42.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(NCC4CC4)c3Cl)C2)cc1 CHEMBL3667166 IC50 42.0 nM
CC1(C)CC2(CCCN(C3CCN(C(=O)c4c5ccccc5cc5ccccc45)CC3)C2)C(=O)O1 CHEMBL1910393 IC50 43.0 nM
CCC1=NC2(CCCN(C3CCN(C(=O)c4c(NC(N)=O)sc5ccccc45)CC3)C2)C(=O)N1CC CHEMBL2030563 IC50 43.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(NCC4CC4)c3F)C2)cc1 CHEMBL3686606 IC50 43.0 nM
C[C@H](NC(=O)c1cnco1)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 CHEMBL3691083 IC50 43.0 nM
CCCOc1ccc(N2CC[C@@H](Oc3ccc(C(C)C(=O)NCC)cc3)C2)cc1 CHEMBL4111688 IC50 43.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCC4CC4)c3Cl)C2)cc1 CHEMBL3974118 IC50 43.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4CC4(F)F)c3F)C2)cc1 CHEMBL3691203 IC50 44.0 nM
CNc1n[nH]c2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc12 CHEMBL3699904 IC50 44.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccc(NC5COC5)nc4c3)CC1)C2 CHEMBL3699919 IC50 44.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCC4CCC4)c3Cl)C2)cc1 CHEMBL3892519 IC50 44.0 nM
CC1(C)CC2(CCCN(C3CCN(C(=O)c4c(NC(=O)NC5CCCCC5)sc5ccccc45)CC3)C2)C(=O)O1 CHEMBL1910401 IC50 45.0 nM
CCCn1cc2c(n1)C(=O)CC1(CCN(C(=O)c3cc(C)c4[nH]ncc4c3)CC1)O2 CHEMBL1958355 IC50 45.0 nM
C[C@H](NC(=O)c1cc[nH]n1)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 CHEMBL3686704 IC50 45.0 nM
C[C@H](NC(=O)c1cnco1)c1ccc(OC2CCN(c3ccnc(N4CCC(F)(F)C4)c3F)C2)cc1 CHEMBL3691088 IC50 45.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4CC4C)c3)C2)cc1 CHEMBL3691166 IC50 45.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4CC4(F)F)c3Cl)C2)cc1 CHEMBL3691212 IC50 45.0 nM
CCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(O[C@@H]3CCN(c4ccnc(OCC5CC5)c4Cl)C3)cc2)s1 CHEMBL3691214 IC50 45.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OC4CCCC4)c3F)C2)cc1 CHEMBL3691225 IC50 45.0 nM
CCN(C)c1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1F CHEMBL3691243 IC50 45.0 nM
COc1c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)ccnc1OCC1CC1(F)F CHEMBL3695322 IC50 45.0 nM
CCC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 CHEMBL3658146 IC50 45.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(OC2CCN(c3ncnc(OCC4CC4)c3F)C2)cc1 CHEMBL3658173 IC50 45.0 nM
CCCOc1ncnc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1Cl CHEMBL3658237 IC50 45.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N4CCCCC4)ncc3F)C2)cc1 CHEMBL3662334 IC50 45.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N4CCC5(CC5)C4)c3F)C2)cc1 CHEMBL3667096 IC50 45.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4[nH]nnc4c3)CC1)C2 CHEMBL3699912 IC50 45.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cc3F)C2)cc1 CHEMBL3942888 IC50 45.0 nM
Cc1oncc1C(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3929740 IC50 45.0 nM
CCOc1ccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(=O)c4sc(NC(=O)COCc5ccccc5)nc4C)cc3)C2)cc1 CHEMBL3931141 IC50 45.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2CCc3cc(OCCC(F)F)ccc3C2)cc1 CHEMBL3895767 IC50 45.0 nM
C[C@H](NC(=O)[C@H]1C[C@H](F)C1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3945142 IC50 45.0 nM
C[C@H](NC(=O)CC#N)c1ccc(CN2Cc3ccc(OCC4CC4(F)F)cc3C(F)C2)cc1 CHEMBL3931587 IC50 45.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 CHEMBL3686495 IC50 46.0 nM
C[C@H](NC(=O)c1cnco1)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3686707 IC50 46.0 nM
C[C@H](NC(=O)c1cnn(C)c1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3917066 IC50 46.0 nM
C[C@H](NC(=O)C1(C#N)CC1)c1ccc(CN2Cc3ccc(OCC4CC4(F)F)cc3C(F)C2)cc1 CHEMBL3947354 IC50 46.0 nM
CCOc1ccc(Oc2ccc(/C=C/[C@H](C)NC(C)=O)cn2)c(Cl)c1 CHEMBL4227033 IC50 46.0 nM
CCC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 CHEMBL220825 IC50 47.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCCC4)c3Cl)C2)cc1 CHEMBL3686638 IC50 47.0 nM
Cc1cc(C(=O)N2CCC3(CC2)Cc2cnn(C(C)(C)C)c2C(=O)N3)cc2c[nH]nc12 CHEMBL3699834 IC50 47.0 nM
Cc1[nH]ncc1C(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3918485 IC50 47.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3cc(OCC4CC(F)(F)C4)ccc3C2)cc1 CHEMBL3944774 IC50 47.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(CN2CCc3cc(OCCC4CC4)ccc3C2)cc1 CHEMBL3909789 IC50 47.0 nM
C[C@H](NC(=O)CO)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3954208 IC50 47.0 nM
Cc1cc2c(cc1C)C(=O)CC1(CCN(C(=O)c3cc(C)c4[nH]ncc4c3)CC1)O2 CHEMBL1091588 IC50 48.0 nM
COc1nc(C)cc2c1C(=O)CC1(CCN(C(=O)c3cc(C)c4[nH]ncc4c3)CC1)O2 CHEMBL1090179 IC50 48.0 nM
CC(=O)NC(C)c1nc(-c2ccc(Oc3ccc(Oc4ccccc4)cc3)cc2)no1 CHEMBL3911590 IC50 48.0 nM
Cc1oncc1C(=O)N[C@@H](C)c1ccc(OC2CCN(c3ncnc(OCC4CC4)c3F)C2)cc1 CHEMBL3658152 IC50 48.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3[C@H](F)C2)cc1 CHEMBL3908725 IC50 48.0 nM
CC(=O)N[C@@H](C)/C=C/c1cnc(Oc2ccc(OCC3CC3)cc2Cl)nc1 CHEMBL4226442 IC50 48.0 nM
CCN1C(=O)OC2(CCCN(C3CCN(C(=O)c4c(NC(N)=O)sc5ccccc45)CC3)C2)C1=O CHEMBL2030408 IC50 49.0 nM
Cc1nocc1C(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(OCC(F)F)c3)C2)cc1 CHEMBL3691057 IC50 49.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(OC2CCN(c3ccnc(OCC4CC4(F)F)c3F)C2)cc1 CHEMBL3691123 IC50 49.0 nM
C[C@H](NC(=O)C(F)F)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 CHEMBL3658191 IC50 49.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OCCCF)c3F)C2)cc1 CHEMBL3662291 IC50 49.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N4CCC(C)C4)c3F)C2)cc1 CHEMBL3662462 IC50 49.0 nM
COC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3957160 IC50 49.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCC4CC4(F)F)c3Cl)C2)cc1 CHEMBL3900267 IC50 49.0 nM
C[C@H](NC(=O)CC#N)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3927368 IC50 49.0 nM
CCNC(=O)N[C@@H](C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3940384 IC50 49.0 nM
CCOc1ccc(N2CC(Oc3ccc([C@H](C)NC(=O)c4cn[nH]c4)cc3)C2)c(C)c1 CHEMBL3407543 IC50 50.0 nM
CC(=O)NC(C)CCc1ccc(Oc2ccc(OCC3CCC3)cn2)cc1 CHEMBL3644832 IC50 50.0 nM
CC(=O)NCCC[C@H]1OC[C@H](Oc2ccc(OCc3ccccc3)cn2)CO1 CHEMBL1630706 IC50 50.0 nM
CCOc1ccc(N2CC(Oc3ccc([C@H](C)NC(=O)c4cn[nH]c4)cc3)C2)cc1 CHEMBL3659831 IC50 50.0 nM
CC(=O)NC(C)Cc1ccc(C#Cc2ccc(OCC3CC3(F)F)cc2)cc1 CHEMBL3690805 IC50 50.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ncc(OC4CCCC4)cc3F)C2)cc1 CHEMBL3686526 IC50 50.0 nM
CCC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3686706 IC50 50.0 nM
CNC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3691092 IC50 50.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(OC2CCN(c3ccnc(N4CCC(F)(F)C4)c3F)C2)cc1 CHEMBL3691109 IC50 50.0 nM
C[C@H](NC(=O)Nc1ccon1)c1ccc(OC2CCN(c3ncnc(OCC4CC4)c3F)C2)cc1 CHEMBL3658176 IC50 50.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)C4CC4)ncc3F)C2)cc1 CHEMBL3662392 IC50 50.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N4CC[C@H](C)C4)c3F)C2)cc1 CHEMBL3667150 IC50 50.0 nM
CC(C)n1ncc2c1C(=O)NC1(CCN(C(=O)C3=CC4C(Cl)=NNC4C=C3)CC1)C2 CHEMBL3699860 IC50 50.0 nM
C[C@H](NC(=O)C1CC(F)C1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3942296 IC50 50.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2CC(=O)c3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3931149 IC50 50.0 nM
C[C@H](NC(=O)CC#N)c1ccc(CN2Cc3ccc(OCC4CC4)cc3[C@@H](F)C2)cc1 CHEMBL3906352 IC50 50.0 nM
COc1cccc2c1C(=O)CC1(CCN(C(=O)c3ccc4[nH]c(-c5ccncc5)nc4c3)CC1)O2 CHEMBL1092606 IC50 51.0 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N(CC)C(=O)N3C)CC1 CHEMBL2030411 IC50 51.0 nM
CNc1nccc2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc12 CHEMBL3699906 IC50 51.0 nM
COc1c(OCC2CC(F)(F)C2)ccc2c1CCN(Cc1ccc([C@H](C)NC(=O)C3CC3)cc1)C2 CHEMBL3899129 IC50 51.0 nM
CC(C)(C)OC(=O)NC[C@H]1CC[C@H](CNC(=O)c2cc(-c3cccc(CN)c3)nc3ccccc23)CC1 CHEMBL1818291 IC50 52.0 nM
CCCNc1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1F CHEMBL3686599 IC50 52.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N4CCC5(CC5)C4)ncc3F)C2)cc1 CHEMBL3667087 IC50 52.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N4CC[C@@H](C)C4)c3F)C2)cc1 CHEMBL3667151 IC50 52.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N4CC[C@H](C)C4)c3Cl)C2)cc1 CHEMBL3667167 IC50 52.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3cc(OCCC4CC4)ccc3C2)cc1 CHEMBL3951590 IC50 52.0 nM
C[C@H](NC(=O)c1ccon1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3904477 IC50 52.0 nM
C[C@H](NC(=O)c1cn[nH]c1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3966387 IC50 52.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OC4CCCC4)c3Cl)C2)cc1 CHEMBL3691222 IC50 53.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(NCC4(O)CCC4)c3F)C2)cc1 CHEMBL3695310 IC50 53.0 nM
C[C@H](NC(=O)c1cn[nH]c1)c1ccc(OC2CCN(c3ncnc(OCC4CC4)c3F)C2)cc1 CHEMBL3658150 IC50 53.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N4CCCCC4)c3Cl)C2)cc1 CHEMBL3662435 IC50 53.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCCCF)cc3)C2)cc1 CHEMBL3906830 IC50 53.0 nM
CCOc1ccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(=O)c4sc(NC(=O)COC(C)=O)nc4C)cc3)C2)cc1 CHEMBL3919997 IC50 53.0 nM
C[C@H](NC(=O)C(F)(F)F)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3938341 IC50 53.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(OCC4CC4(F)F)c3)C2)cc1 CHEMBL3686513 IC50 54.0 nM
C[C@H](NC(=O)C(F)(F)F)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3691133 IC50 54.0 nM
CCN(C)c1nccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 CHEMBL3699923 IC50 54.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3985056 IC50 54.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCCC(F)(F)F)c3Cl)C2)cc1 CHEMBL3965239 IC50 54.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(SC(C)C)cc2)s1 CHEMBL377535 IC50 55.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(OC2CCN(c3ccc(F)c(C(F)(F)F)n3)C2)cc1 CHEMBL3686550 IC50 55.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3cccc(C(C)C)n3)C2)cc1 CHEMBL3686555 IC50 55.0 nM
CCC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 CHEMBL3686674 IC50 55.0 nM
C[C@H](NC(=O)c1cncs1)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 CHEMBL3686699 IC50 55.0 nM
COCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(OC3CCN(c4ccnc(OCC(F)F)c4)C3)cc2)s1 CHEMBL3691058 IC50 55.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4CC4C#N)c3)C2)cc1 CHEMBL3691167 IC50 55.0 nM
CC[C@H](C)Oc1cc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)ccn1 CHEMBL3691170 IC50 55.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4CC4)c3C)C2)cc1 CHEMBL3691198 IC50 55.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC(C)C)c3C)C2)cc1 CHEMBL3691199 IC50 55.0 nM
C[C@H](NC(=O)c1cncs1)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3691204 IC50 55.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)C)ncc3F)C2)cc1 CHEMBL3667189 IC50 55.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 CHEMBL3662370 IC50 55.0 nM
COc1nccc2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc12 CHEMBL3699907 IC50 55.0 nM
C[C@H](NC(=O)c1cnn(C)c1Cl)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3942326 IC50 55.0 nM
CCNC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3940892 IC50 55.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2CCc3c(ccc(OCC4(C(F)(F)F)CC4)c3Cl)C2)cc1 CHEMBL3923768 IC50 55.0 nM
COc1c(OCC2CC(F)(F)C2)ccc2c1CCN(Cc1ccc([C@H](C)NC(C)=O)cc1)C2 CHEMBL3974947 IC50 55.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2Cc3ccc(OCC4CCC4)cc3C(O)C2)cc1 CHEMBL3922542 IC50 55.0 nM
C[C@H](NC(=O)CO)c1ccc(CN2Cc3ccc(OCC4CC4(F)F)cc3C(F)C2)cc1 CHEMBL3902114 IC50 55.0 nM
C[C@H](NC(=O)C1(N)CC1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3914837 IC50 55.0 nM
CCn1nc2c(c1C)OC1(CCN(C(=O)c3cc(C)c4nc(C)[nH]c4c3)CC1)CC2=O CHEMBL1958370 IC50 56.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)CCC(F)(F)F)ncc3F)C2)cc1 CHEMBL3662480 IC50 56.0 nM
COc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cnn(C(C)C)c3C(=O)N4)cc2n1 CHEMBL3699854 IC50 56.0 nM
CC(C)n1ncc2c1C(=O)NC1(CCN(C(=O)C3=CC4NC=C(Cl)C4N=C3)CC1)C2 CHEMBL3699858 IC50 56.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4c(N)n[nH]c4c3)CC1)C2 CHEMBL3699888 IC50 56.0 nM
CC(C#N)C(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3891398 IC50 56.0 nM
C[C@H](NC(=O)Nc1ccon1)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3954727 IC50 56.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(CN3Cc4ccc(OCC5CC5)cc4C(F)C3)cc2)s1 CHEMBL3904011 IC50 56.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(Oc3ccccn3)cc2)s1 CHEMBL435145 IC50 57.0 nM
Cc1cc(NC(C)C#Cc2cnc(Oc3ccc(Oc4ccccc4)cc3)s2)on1 CHEMBL397400 IC50 57.0 nM
Cc1nocc1C(=O)N[C@@H](C)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 CHEMBL3686684 IC50 57.0 nM
CCCOc1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1Cl CHEMBL3691219 IC50 57.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(NCC4(O)CCC4)c3Cl)C2)cc1 CHEMBL3695315 IC50 57.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N4CCC[C@H]4C)ncc3F)C2)cc1 CHEMBL3667142 IC50 57.0 nM
CC(C(=O)NC1CC1)c1ccc(O[C@@H]2CCN(c3ncnc(OCC(C)(C)O)c3Cl)C2)cc1 CHEMBL4111687 IC50 57.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCCCF)c3Cl)C2)cc1 CHEMBL3959825 IC50 57.0 nM
CCCOc1ccc2c(c1)CCN(Cc1ccc([C@H](C)NC(=O)C3CC3)cc1)C2 CHEMBL3954533 IC50 57.0 nM
CC(C)COc1ccc2c(c1)CCN(Cc1ccc([C@H](C)NC(=O)C3CC3)cc1)C2 CHEMBL3933364 IC50 57.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(OC3CCN(c4ccnc(N5CCC(F)(F)C5)c4F)C3)cc2)s1 CHEMBL3691085 IC50 58.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC(C)(F)F)c3F)C2)cc1 CHEMBL3691226 IC50 58.0 nM
COc1c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)ccnc1OCC(F)F CHEMBL3695321 IC50 58.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OC4CCCC4)c3F)C2)cc1 CHEMBL3662307 IC50 58.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)C4CCCC4)ncc3F)C2)cc1 CHEMBL3662337 IC50 58.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)CC4CC4)ncc3Cl)C2)cc1 CHEMBL3662449 IC50 58.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCC(C)C)c3Cl)C2)cc1 CHEMBL3947589 IC50 58.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3966663 IC50 58.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(CN3Cc4ccc(OCC5CC5(F)F)cc4C(F)C3)cc2)s1 CHEMBL3913578 IC50 58.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2CCc3c(cccc3OC3CCC3)C2)cc1 CHEMBL3946077 IC50 58.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(O[C@@H]3CCN(c4ccnc(OCC5CC5)c4)C3)cc2)s1 CHEMBL3686536 IC50 59.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3cc(OCC4CC4)ncc3F)C2)cc1 CHEMBL3686565 IC50 59.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CC(F)(F)C4)c3F)C2)cc1 CHEMBL3686597 IC50 59.0 nM
COC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 CHEMBL3691113 IC50 59.0 nM
CCCOc1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1C CHEMBL3691196 IC50 59.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC(C)(F)F)c3Cl)C2)cc1 CHEMBL3691218 IC50 59.0 nM
CCN(C)c1nccc(N2CCC(Oc3ccc([C@H](C)NC(=O)C(F)F)cc3)C2)n1 CHEMBL3658190 IC50 59.0 nM
CCN(CC)c1ncc(Cl)c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)n1 CHEMBL3662385 IC50 59.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N4CCC(C)C4)ncc3F)C2)cc1 CHEMBL3662394 IC50 59.0 nM
CCN(CC)c1ncnc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1Cl CHEMBL3662427 IC50 59.0 nM
C[C@H](NC(=O)C1(C(F)(F)F)CC1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3944012 IC50 59.0 nM
C[C@H](NC(=O)c1cnco1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3959015 IC50 59.0 nM
C[C@H](NC(=O)c1cncs1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3906993 IC50 59.0 nM
CNC(=O)N[C@@H](C)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3952473 IC50 59.0 nM
CC(=O)N[C@@H](C)/C=C/c1ccc(Oc2ccc3nc(C(C)C)sc3c2C(F)(F)F)nc1 CHEMBL4226825 IC50 59.0 nM
CC(=O)N[C@@H](C)CO[C@H]1CC[C@H](Oc2ccc(OC(C)C)nc2)CC1 CHEMBL1630703 IC50 60.0 nM
CC(=O)N[C@@H](C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 CHEMBL1630516 IC50 60.0 nM
CCCOc1ccc(C2CCN(c3ccc(C(C)NC(C)=O)cc3F)CC2)c(C)c1 CHEMBL3407541 IC50 60.0 nM
CC(=O)NC(C)CCc1ccc(Oc2ccc(OC(C)C)nc2)cc1 CHEMBL3644839 IC50 60.0 nM
CCCOc1ccc(N2CC(Oc3ccc([C@H](C)NC(=O)C4CC4)cc3)C2)cc1 CHEMBL3659727 IC50 60.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CN(c3ccc(OCC4CC4)cc3F)C2)cc1 CHEMBL3659756 IC50 60.0 nM
CC(=O)NC(C)Cc1ccc(C#Cc2ccc(OCCC3CC3)cc2)cc1 CHEMBL3690787 IC50 60.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3686509 IC50 60.0 nM
C[C@H](NC(=O)c1cncs1)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 CHEMBL3686687 IC50 60.0 nM
C[C@H](NC(=O)c1cncs1)c1ccc(OC2CCN(c3ccnc(N4CCC(F)(F)C4)c3F)C2)cc1 CHEMBL3691087 IC50 60.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OCC(C)(F)F)c3Cl)C2)cc1 CHEMBL3662299 IC50 60.0 nM
CCN(C)c1ncc(Cl)c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)n1 CHEMBL3662381 IC50 60.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N(C)C4CCC4)c3F)C2)cc1 CHEMBL3667093 IC50 60.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N4CCCC4C)ncc3F)C2)cc1 CHEMBL3667115 IC50 60.0 nM
COc1ccc2ncc(C(=O)N3CCC4(CC3)Cc3cnn(C(C)C)c3C(=O)N4)cc2c1 CHEMBL3699852 IC50 60.0 nM
CCCOc1ccc(N2CCC(Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c(Cl)c1 CHEMBL3958831 IC50 60.0 nM
CCCOc1ccc2c(c1)CCN(Cc1ccc(C(C)NC(C)=O)cc1)C2 CHEMBL3929163 IC50 60.0 nM
C[C@H](NC(=O)Cc1cnccn1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3934676 IC50 60.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCCCC4)c3F)C2)cc1 CHEMBL3686594 IC50 61.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC(F)F)c3F)C2)cc1 CHEMBL3691193 IC50 61.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC(F)(F)C4)cc3)C2)cc1 CHEMBL3943451 IC50 61.0 nM
C[C@H](NC(=O)c1ccno1)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3890130 IC50 61.0 nM
CCCNc1nccc(N2CC[C@@H](Oc3ccc(C(C)C(=O)NC4CC4)cc3)C2)c1F CHEMBL4113866 IC50 61.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCCC4CC4)c3Cl)C2)cc1 CHEMBL3982220 IC50 61.0 nM
CCCNc1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1Cl CHEMBL3686627 IC50 62.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 CHEMBL3691134 IC50 62.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(NCC4CCC4)c3Cl)C2)cc1 CHEMBL3667168 IC50 62.0 nM
C[C@H](NC(=O)C1(C#N)CC1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3910702 IC50 62.0 nM
CCn1cc2c(n1)C(=O)CC1(CCN(C(=O)c3cc(C)c4[nH]ncc4c3)CC1)O2 CHEMBL1958353 IC50 63.0 nM
Cc1cc(C(=O)N2CCC3(CC2)CC(=O)c2nn(C4CCCCC4)cc2O3)cc2cn[nH]c12 CHEMBL1955891 IC50 63.0 nM
CC1C(=O)c2nn(C(C)(C)C)cc2OC12CCN(C(=O)c1ccc3[nH]ncc3c1)CC2 CHEMBL3359259 IC50 63.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3cc(OCC4CC4(F)F)ncc3F)C2)cc1 CHEMBL3686568 IC50 63.0 nM
C[C@H](NC(=O)c1cn[nH]c1)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3691048 IC50 63.0 nM
CCN(C)c1nccc(N2CCC(Oc3ccc([C@H](C)NC(=O)C4CC4)cc3)C2)n1 CHEMBL3658144 IC50 63.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OCC4CC4(F)F)c3F)C2)cc1 CHEMBL3662294 IC50 63.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(CN2CCc3c(ccc(OCC4CC4(F)F)c3Cl)C2)cc1 CHEMBL3893506 IC50 63.0 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(CCN(C)C3=O)C2)CC1 CHEMBL2030566 IC50 64.0 nM
CCOc1ccc(N2CCN(c3noc(CNC(C)=O)n3)[C@@H](C)C2)c(C)c1 CHEMBL3110091 IC50 64.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(O[C@@H]3CCN(c4cccc(C(F)(F)F)n4)C3)cc2)s1 CHEMBL3686537 IC50 64.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)C4CCC4)ncc3Cl)C2)cc1 CHEMBL3667127 IC50 64.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)c(F)c3)C2)cc1 CHEMBL3957401 IC50 64.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ncc(OC4CCC4)cc3F)C2)cc1 CHEMBL3686514 IC50 65.0 nM
CCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(O[C@@H]3CCN(c4ccnc(NCC5CC5)c4Cl)C3)cc2)s1 CHEMBL3686632 IC50 65.0 nM
CC(C)Oc1cc(N2CCC(Oc3ccc([C@H](C)NC(=O)c4cn[nH]c4)cc3)C2)ccn1 CHEMBL3686649 IC50 65.0 nM
C[C@H](NC(=O)C1(C)CC1)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3691037 IC50 65.0 nM
CC(C)Oc1cc(N2CCC(Oc3ccc([C@H](C)NC(=O)N(C)C)cc3)C2)ccn1 CHEMBL3691090 IC50 65.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC4CC(F)(F)C4)c3)C2)cc1 CHEMBL3691202 IC50 65.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(NCC(C)(C)O)c3Cl)C2)cc1 CHEMBL3695311 IC50 65.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 CHEMBL3658131 IC50 65.0 nM
COC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 CHEMBL3658184 IC50 65.0 nM
C[C@H](NC(=O)C(F)F)c1ccc(OC2CCN(c3ncnc(OCC4CC4)c3F)C2)cc1 CHEMBL3658192 IC50 65.0 nM
CCCOc1ncnc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1F CHEMBL3658235 IC50 65.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)CC(F)F)ncc3F)C2)cc1 CHEMBL3662353 IC50 65.0 nM
CCCN(C)c1ncc(Cl)c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)n1 CHEMBL3662373 IC50 65.0 nM
COCCN(C)c1ncc(F)c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)n1 CHEMBL3662390 IC50 65.0 nM
CCCOc1ccc(N2CCC(Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c(C)c1 CHEMBL3960766 IC50 65.0 nM
Cc1nocc1C(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3959054 IC50 65.0 nM
C[C@H](NC(=O)c1cnn(C)c1N)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3962076 IC50 65.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(CN2CCc3cc(OCC4CC4)ccc3C2)cc1 CHEMBL3985028 IC50 65.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2CC(=O)c3cc(OCC4CC4)ccc3C2)cc1 CHEMBL3976925 IC50 65.0 nM
CC(=O)N[C@@H](C)/C=C/c1cnc(Oc2ccc(OC(C)C)cc2)s1 CHEMBL4225651 IC50 66.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC3CCOC3)cc2)s1 CHEMBL219665 IC50 67.0 nM
CCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(O[C@@H]3CCN(c4ccnc(NCC5CC5)c4F)C3)cc2)s1 CHEMBL3686634 IC50 67.0 nM
CCC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OC[C@H]4CC4(F)F)cn3)C2)cc1 CHEMBL3691053 IC50 67.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OCC4CC4)c3C)C2)cc1 CHEMBL3662285 IC50 67.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N4CCCC4)ncc3F)C2)cc1 CHEMBL3662338 IC50 67.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N4CCCC4)c3F)C2)cc1 CHEMBL3662452 IC50 67.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)C3=CC4C=NNC4C=C3)CC1)C2 CHEMBL3699867 IC50 67.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3cc(OCC4CCC4)ccc3C2)cc1 CHEMBL3933480 IC50 67.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2CCc3c(ccc(Cl)c3Cl)C2)cc1 CHEMBL3938129 IC50 67.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N(C)CC(F)(F)F)c3F)C2)cc1 CHEMBL3686604 IC50 68.0 nM
COC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(OCC4CC4(F)F)c3F)C2)cc1 CHEMBL3691116 IC50 68.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OC4CC=CC4)c3)C2)cc1 CHEMBL3691155 IC50 68.0 nM
COc1cccc2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cnc12 CHEMBL3699891 IC50 68.0 nM
COc1c(OCC2CC2)ccc2c1CCN(Cc1ccc([C@H](C)NC(C)=O)cc1)C2 CHEMBL3942786 IC50 68.0 nM
C[C@H](NC(=O)c1ccns1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3915162 IC50 68.0 nM
CC(=O)NC(C)C#Cc1cnc(Sc2ccc(OC(C)C)cc2)s1 CHEMBL208880 IC50 69.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2Cl)s1 CHEMBL233392 IC50 69.0 nM
COCCN(C)c1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1F CHEMBL3686598 IC50 69.0 nM
COc1c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)ccnc1OC(C)C CHEMBL3686640 IC50 69.0 nM
C[C@H](NC(=O)c1cn[nH]c1)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 CHEMBL3686675 IC50 69.0 nM
Cc1oncc1C(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(OC(C)C)c3)C2)cc1 CHEMBL3686698 IC50 69.0 nM
C[C@H](NC(=O)c1cnn(C)c1)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3691040 IC50 69.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OCC(C)C)c3F)C2)cc1 CHEMBL3662288 IC50 69.0 nM
COc1c(OC2CCCC2)ncnc1N1CC[C@@H](Oc2ccc([C@H](C)NC(C)=O)cc2)C1 CHEMBL3662315 IC50 69.0 nM
CCN(CC)c1ncc(F)c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)n1 CHEMBL3662352 IC50 69.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3C)C2)cc1 CHEMBL3894973 IC50 69.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC(C)C)cc2[N+](=O)[O-])s1 CHEMBL232944 IC50 70.0 nM
CC(=O)NC(C)CCc1ccc(Oc2ccc(OCc3ccccc3)nc2)cc1 CHEMBL1630712 IC50 70.0 nM
CCCOc1ccc(N2CC(Oc3ccc([C@H](C)NC(C)=O)cc3)C2)cc1 CHEMBL3659706 IC50 70.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3659707 IC50 70.0 nM
CC(=O)NC(C)c1ccc(C#Cc2ccc(OC3CC3)cc2)cc1 CHEMBL3686235 IC50 70.0 nM
CCOc1ccc(C#Cc2ccc(CC(C)NC(=O)c3cncs3)cc2)cc1 CHEMBL3690694 IC50 70.0 nM
CCOc1ccc(C#Cc2ccc(CC(C)NC(=O)c3cn[nH]c3)cc2)cc1 CHEMBL3690695 IC50 70.0 nM
CC(Cc1ccc(C#Cc2cnc(OC3CCC3)nc2)cc1)NC(=O)N(C)C CHEMBL3694919 IC50 70.0 nM
CC(=O)N[C@@H](C)c1ccc(C#Cc2ccc(OC3CCC3)cc2)cc1 CHEMBL3695058 IC50 70.0 nM
CCCOc1ccc(C#Cc2ccc(C[C@H](C)NC(C)=O)cc2)cc1 CHEMBL3698587 IC50 70.0 nM
CCCOc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)cc1 CHEMBL3698597 IC50 70.0 nM
CCCOc1ccc(C#Cc2ccc(C(C)CNC(C)=O)cc2)cc1 CHEMBL3698611 IC50 70.0 nM
CC(=O)NCC(C)c1ccc(C#Cc2cnc(OC3CCC3)nc2)cc1 CHEMBL3698613 IC50 70.0 nM
CCCOc1ccc(C#Cc2ccc(CC(C)(C)NC(C)=O)cc2)cc1 CHEMBL3698619 IC50 70.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OC4CCCC4)cn3)C2)cc1 CHEMBL3686521 IC50 70.0 nM
CCCOc1cc(N2CCC(Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c(F)cn1 CHEMBL3686564 IC50 70.0 nM
CCCN(C)c1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1F CHEMBL3686595 IC50 70.0 nM
Cc1nocc1C(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(OC(C)C)c3)C2)cc1 CHEMBL3686646 IC50 70.0 nM
COC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3691114 IC50 70.0 nM
CCC(CC)Oc1cc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)ccn1 CHEMBL3691164 IC50 70.0 nM
C[C@H](NC(=O)c1cn[nH]c1)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 CHEMBL3658145 IC50 70.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)CC(F)F)ncc3Cl)C2)cc1 CHEMBL3662459 IC50 70.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(NCC4(O)CCC4)c3Cl)C2)cc1 CHEMBL3667156 IC50 70.0 nM
COc1c(OCC(C)C)ccc2c1CCN(Cc1ccc([C@H](C)NC(C)=O)cc1)C2 CHEMBL3962749 IC50 70.0 nM
CC(C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1)NC(=O)N(C)C CHEMBL391391 IC50 71.0 nM
CCCOc1ccc(N2CCN(c3noc(CC)n3)[C@@H](C)C2)c(C)c1 CHEMBL3110098 IC50 71.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)C(C)C)ncc3F)C2)cc1 CHEMBL3662388 IC50 71.0 nM
C[C@H](NC(=O)CC#N)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3925016 IC50 71.0 nM
C[C@H](NC(=O)c1ccon1)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3983149 IC50 71.0 nM
CC(C)Oc1ccc2c(c1)CCN(Cc1ccc([C@H](C)NC(=O)C3CC3)cc1)C2 CHEMBL3897100 IC50 71.0 nM
C[C@H](NC(=O)C1(C)CC1)c1ccc(OC2CCN(c3ccnc(N4CCC(F)(F)C4)c3F)C2)cc1 CHEMBL3691086 IC50 72.0 nM
CC(C)n1ncc2c1C(=O)NC1(CCN(C(=O)C3=CC4C=NNC4C(Cl)=C3)CC1)C2 CHEMBL3699837 IC50 72.0 nM
CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(c3ccc(OC4CCCC4)cc3)C2)cc1 CHEMBL4115051 IC50 72.0 nM
C[C@H](NC(=O)C1CCC1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3916098 IC50 72.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(OC2CCN(c3ccnc(OCC(F)F)c3F)C2)cc1 CHEMBL3691128 IC50 73.0 nM
CNC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3894526 IC50 73.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3897266 IC50 74.0 nM
CC(C#Cc1cnc(Oc2ccc(Oc3ccccc3)cc2)s1)N(O)C(N)=O CHEMBL378186 IC50 75.0 nM
CCN1C(=O)C2(CCCN(C3CCN(C(=O)c4c(NC(N)=O)sc5ccccc45)CC3)C2)N=C1C CHEMBL2030562 IC50 75.0 nM
CCNC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3691091 IC50 75.0 nM
CCC(C)Oc1cc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)ccn1 CHEMBL3691148 IC50 75.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCCC4CC4)c3)C2)cc1 CHEMBL3691158 IC50 75.0 nM
CCN(C)c1nccc(N2CCC(Oc3ccc([C@H](C)NC(=O)OC)cc3)C2)n1 CHEMBL3658187 IC50 75.0 nM
COc1c(OCC2CC2(F)F)ncnc1N1CC[C@@H](Oc2ccc([C@H](C)NC(C)=O)cc2)C1 CHEMBL3662316 IC50 75.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)C[C@@H]4CCCO4)ncc3F)C2)cc1 CHEMBL3662487 IC50 75.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N(C)CCC(F)(F)F)n3)C2)cc1 CHEMBL3667067 IC50 75.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2cccc(Oc3ccccc3)c2)s1 CHEMBL375380 IC50 76.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4[nH]ncc4c3)CC1)C2 CHEMBL2419603 IC50 76.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCC(F)(F)C4)c3C)C2)cc1 CHEMBL3686616 IC50 76.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCC4)c3Cl)C2)cc1 CHEMBL3686623 IC50 76.0 nM
C[C@H](NC(=O)c1cncs1)c1ccc(OC2CCN(c3ccnc(OCC(F)F)c3)C2)cc1 CHEMBL3691063 IC50 76.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCC4CC4(F)F)c3Br)C2)cc1 CHEMBL3923680 IC50 76.0 nM
CCNC(=O)N[C@@H](C)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3972357 IC50 76.0 nM
COC(=O)N[C@@H](C)/C=C/c1cnc(Oc2ccc(OC(C)C)cc2)s1 CHEMBL4226756 IC50 76.0 nM
C[C@H](NC(=O)C(F)(F)F)c1ccc(OC2CCN(c3ccnc(OCC(F)F)c3)C2)cc1 CHEMBL3691075 IC50 77.0 nM
CCCNc1nccc(N2CCC(Oc3ccc([C@H](C)NC(=O)OC)cc3)C2)c1F CHEMBL3691118 IC50 77.0 nM
C=C(C)COc1cc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)ccn1 CHEMBL3691161 IC50 77.0 nM
CCC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ncnc(OCC4CC4)c3OC)C2)cc1 CHEMBL3658155 IC50 77.0 nM
CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccnc(NC5COC5)c4c3)CC1)C2 CHEMBL3699928 IC50 77.0 nM
C[C@H](NC(=O)[C@H]1C[C@H](F)C1)c1ccc(CN2Cc3ccc(OCC4CC4(F)F)cc3C(F)C2)cc1 CHEMBL3986839 IC50 77.0 nM
CNC(=O)NC(C)c1ccc2nc(-c3ccc(Oc4cccc(OCC5CC5)c4)nc3)oc2c1 CHEMBL4577890 IC50 77.0 nM
CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(CCNC3=O)C2)CC1 CHEMBL2030565 IC50 79.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC(F)F)c3Cl)C2)cc1 CHEMBL3691213 IC50 79.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCC(F)(F)C4)n3)C2)cc1 CHEMBL3662369 IC50 79.0 nM
CCN(CC)c1ncnc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1F CHEMBL3662418 IC50 79.0 nM
C[C@H](NC(=O)c1cncs1)c1ccc(O[C@@H]2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 CHEMBL3662420 IC50 79.0 nM
COCCN(C)c1ncc(Cl)c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)n1 CHEMBL3662453 IC50 79.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N(C)C4CCC4)n3)C2)cc1 CHEMBL3667114 IC50 79.0 nM
C[C@H](NC(=O)C1(C)CC1)c1ccc(O[C@@H]2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 CHEMBL3960673 IC50 79.0 nM
CCCOc1ccc2c(c1OC)CCN(Cc1ccc([C@H](C)NC(C)=O)cc1)C2 CHEMBL3951531 IC50 79.0 nM
CCOc1ccc(Oc2ncc(/C=C/[C@H](C)NC(C)=O)s2)cc1 CHEMBL4226491 IC50 79.0 nM
CC(C)Oc1ccc(Oc2ccc(CC[C@H](C)NC(=O)C3CC3)cc2)cn1 CHEMBL1630701 IC50 80.0 nM
CCn1nc2c(c1C)OC1(CCN(C(=O)c3cc(C)c4nc[nH]c4c3)CC1)CC2=O CHEMBL1958369 IC50 80.0 nM
Cc1cc(OCC2CC2)ccc1C1CCN(c2ccc(C(C)C(=O)NC3CC3)cc2)CC1 CHEMBL3407542 IC50 80.0 nM
CC(=O)NC(C)CCC1CCC(Oc2ccc(OC(C)C)nc2)CC1 CHEMBL3644845 IC50 80.0 nM
CC(=O)NC(C)c1ccc(OC2CN(c3ccc(OC4CCCC4)cc3)C2)cc1 CHEMBL3659699 IC50 80.0 nM
CCCOc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)c(Cl)c1 CHEMBL3639894 IC50 80.0 nM
CC(=O)NC(C)Cc1ccc(C#Cc2ccc(OCC3CC3)cc2)cc1 CHEMBL3690786 IC50 80.0 nM
C=C1CCN(c2ncc(C#Cc3ccc(CC(C)NC(C)=O)cc3)cn2)CC1 CHEMBL3695042 IC50 80.0 nM
CCCOc1ccc(C#Cc2ccc(CC(C)NC(=O)C3CC3)cc2)cc1 CHEMBL3698554 IC50 80.0 nM
CC(Cc1ccc(C#Cc2ccc(OC3CCCC3)cc2)cc1)NC(=O)C1CC1 CHEMBL3698561 IC50 80.0 nM
CCOc1ccc(C#Cc2ccc(C[C@H](C)NC(C)=O)cc2)cn1 CHEMBL3698586 IC50 80.0 nM
CCOc1ccc(C#Cc2ccc(C[C@H](C)NC(C)=O)cc2)cc1 CHEMBL3698598 IC50 80.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OC(C)C)c3F)C2)cc1 CHEMBL3691224 IC50 80.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCC(C)(O)C4)c3F)C2)cc1 CHEMBL3695312 IC50 80.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N4CCC(F)(F)C4)c3Cl)C2)cc1 CHEMBL3662437 IC50 80.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OC4CCC4)c3Cl)C2)cc1 CHEMBL3970881 IC50 80.0 nM
CC(NC(=O)N(C)C)c1ccc2nc(-c3ccc(Oc4cccc(OCC5CC5)c4)nc3)oc2c1 CHEMBL4435891 IC50 80.0 nM
CC(=O)NC(C)C#Cc1cnc(Oc2ccc(CC(C)C)cc2)s1 CHEMBL387155 IC50 81.0 nM
C[C@H](NC(=O)Nc1ccon1)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 CHEMBL3691089 IC50 81.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OCC(C)(C)O)c3Cl)C2)cc1 CHEMBL3662302 IC50 81.0 nM
C[C@H](NC(=O)Cc1cncnc1)c1ccc(CN2CCc3cc(OC[C@@H]4CC4(F)F)ccc3C2)cc1 CHEMBL3982729 IC50 81.0 nM
CCOc1nccc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1OC CHEMBL3686587 IC50 82.0 nM
C[C@H](NC(=O)Cc1cncnc1)c1ccc(CN2CCc3cc(OCC4CC4)ccc3C2)cc1 CHEMBL3899203 IC50 82.0 nM
C[C@H](NC(=O)CO)c1ccc(CN2CCc3cc(OCC4CC4)ccc3C2)cc1 CHEMBL3970387 IC50 82.0 nM
Cc1cc(NC(C)C#Cc2cnc(Oc3ccc(Oc4ccccc4)cc3)s2)no1 CHEMBL247612 IC50 83.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(CN2CCc3cc(OCCC(F)(F)F)ccc3C2)cc1 CHEMBL3924631 IC50 83.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(OC2CCN(c3ccc(OC[C@H]4CC4(F)F)cn3)C2)cc1 CHEMBL3691056 IC50 84.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc4c(c3)OCCCO4)C2)cc1 CHEMBL3926160 IC50 84.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3[C@@H](O)C2)cc1 CHEMBL3928886 IC50 84.0 nM
CC(=O)N[C@@H](C)/C=C/c1ccc(Oc2ccc(OCC(F)F)cc2Cl)nc1 CHEMBL4224836 IC50 84.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3686545 IC50 85.0 nM
C[C@H](NC(=O)C1(C#N)CC1)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3686705 IC50 85.0 nM
C[C@H](NC(=O)c1cn[nH]c1)c1ccc(OC2CCN(c3ccnc(OCC(F)F)c3)C2)cc1 CHEMBL3691061 IC50 85.0 nM
C[C@H](NC(=O)c1cnco1)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 CHEMBL3691084 IC50 85.0 nM
C[C@H](NC(=O)c1cncs1)c1ccc(O[C@@H]2CCN(c3ccnc(OC4CCOC4)c3)C2)cc1 CHEMBL3691206 IC50 85.0 nM
CCC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(N(C)CC)n3)C2)cc1 CHEMBL3658143 IC50 85.0 nM
COC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ncnc(OCC4CC4)c3F)C2)cc1 CHEMBL3658188 IC50 85.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N4CCC(C)(C)C4)c3F)C2)cc1 CHEMBL3667061 IC50 85.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC(C)(F)F)cc3)C2)cc1 CHEMBL3891856 IC50 85.0 nM
C[C@H](NC(=O)c1cncs1)c1ccc(CN2CCc3c(cccc3C(F)(F)F)C2)cc1 CHEMBL3918293 IC50 85.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccc(F)c(C(F)(F)F)n3)C2)cc1 CHEMBL3691139 IC50 86.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OCC(C)(F)F)c3F)C2)cc1 CHEMBL3662293 IC50 86.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OC4CC4)cc3C)C2)cc1 CHEMBL3957568 IC50 86.0 nM
CC(C(=O)NC1CC1C)c1ccc(O[C@@H]2CCN(c3nc(N(C)C)ncc3F)C2)cc1 CHEMBL4108023 IC50 86.0 nM
CCN(C)c1cc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c(F)cn1 CHEMBL3691252 IC50 87.0 nM
C[C@H](NC(=O)c1cnco1)c1ccc(OC2CCN(c3ncnc(OCC4CC4)c3F)C2)cc1 CHEMBL3658151 IC50 87.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OC[C@@H]4CC4(F)F)c3F)C2)cc1 CHEMBL3662308 IC50 87.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4)c(F)c3)C2)cc1 CHEMBL3938851 IC50 87.0 nM
CC(=O)NC(C)c1ccc(-c2ccc(Oc3ccc(OC(C)C)cc3)cc2C)c(C)c1 CHEMBL584907 IC50 88.0 nM
CCCOc1cnc(N2CCC(Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c(Cl)c1 CHEMBL3686563 IC50 88.0 nM
CCC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(OCC(F)F)c3)C2)cc1 CHEMBL3691068 IC50 88.0 nM
CCN(C)c1ncnc(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c1Cl CHEMBL3662425 IC50 88.0 nM
CC(C)(C)OC(=O)NC[C@H]1CC[C@H](CNC(=O)c2cc(N3CCC(CCN)CC3)nc3ccccc23)CC1 CHEMBL1818297 IC50 89.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3cccc(C4CCC4)n3)C2)cc1 CHEMBL3686578 IC50 89.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N(C)CC(F)(F)F)n3)C2)cc1 CHEMBL3662372 IC50 89.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N4CCC[C@H]4C)ncc3Cl)C2)cc1 CHEMBL3667144 IC50 89.0 nM
CC(=O)N[C@@H](C)c1ccc(CN2CC(=O)c3cc(OCc4ccccc4)ccc3C2)cc1 CHEMBL3915203 IC50 89.0 nM
C[C@H](NC(=O)CO)c1ccc(CN2CCc3cc(OC[C@@H]4CC4(F)F)ccc3C2)cc1 CHEMBL3952916 IC50 89.0 nM
CC(CCc1ccc(Oc2ccc(OC(C)C)nc2)cc1)NC(=O)C1CC1 CHEMBL1630700 IC50 90.0 nM
CCOc1ccc(N2CC(Oc3ccc([C@H](C)NC(C)=O)cc3)C2)cc1 CHEMBL3659711 IC50 90.0 nM
CCCOc1ccc(N2CC(Oc3ccc([C@H](C)NC(C)=O)cc3)C2)nc1 CHEMBL3659744 IC50 90.0 nM
CCCOc1ccc(N2CC(Oc3ccc([C@H](C)NC(C)=O)cc3)C2)c(Cl)c1 CHEMBL3659760 IC50 90.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CN(c3ncc(-c4ccc(F)cc4)cn3)C2)cc1 CHEMBL3659819 IC50 90.0 nM
CCCCOc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)cc1 CHEMBL3690769 IC50 90.0 nM
CC(=O)NC(C)Cc1ccc(C#Cc2cnc(OC3CCC3)nc2)cc1 CHEMBL3694902 IC50 90.0 nM
CCCCOc1ccc(C#Cc2ccc(CC(C)NC(=O)C3CC3)cc2)cc1 CHEMBL3698545 IC50 90.0 nM
CC(=O)N[C@@H](C)Cc1ccc(C#Cc2ccc(C(C)(C)C)cc2)cc1 CHEMBL3698585 IC50 90.0 nM
CCN(C)C(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 CHEMBL3691095 IC50 90.0 nM
C[C@H](NC(=O)N(C)C)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 CHEMBL3691121 IC50 90.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCc4ccc(F)cc4)c3)C2)cc1 CHEMBL3691150 IC50 90.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCC(F)F)c3)C2)cc1 CHEMBL3691174 IC50 90.0 nM
Cc1oncc1C(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 CHEMBL3658142 IC50 90.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N(C)C4CCCC4)c3F)C2)cc1 CHEMBL3662448 IC50 90.0 nM
CC1=NNC2C=CC(C(=O)N3CCC4(CC3)Cc3cnn(C(C)C)c3C(=O)N4)=CC12 CHEMBL3699842 IC50 90.0 nM
Cc1cc(OC2CC2)ccc1N1CC[C@@H](Oc2ccc([C@H](C)NC(=O)c3cnoc3C)cc2)C1 CHEMBL3903602 IC50 90.0 nM
C[C@H](NC(=O)[C@@H](C)O)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 CHEMBL3927625 IC50 90.0 nM
CCC1=CC(C(=O)N2CCC3(CC2)Cc2cnn(C(C)C)c2C(=O)N3)=CC2C=NNC12 CHEMBL3699840 IC50 91.0 nM
CC(C)n1ncc2c1C(=O)NC1(CCN(C(=O)C3=CC4N=C(N)NC4C=C3)CC1)C2 CHEMBL3699861 IC50 91.0 nM
CC(C#N)C(=O)N[C@@H](C)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 CHEMBL3944981 IC50 91.0 nM
CCn1nc2c(c1C)OC1(CCN(C(=O)c3ccc4[nH]ncc4c3)CC1)CC2=O CHEMBL1958367 IC50 92.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCC4)c3F)C2)cc1 CHEMBL3686593 IC50 92.0 nM
CNC(=O)N[C@@H](C)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 CHEMBL3691107 IC50 92.0 nM
CC(C)(C)n1cc2c(n1)C(=O)CC1(CCN(C(=O)c3cccc(-c4ccc(C(=O)O)cc4)c3)CC1)O2 CHEMBL4777931 IC50 92.0 nM
CC(=O)NC(C)c1ccc(-c2ccc(Oc3ccc(OC(C)C)cc3)nc2)cc1 CHEMBL566681 IC50 93.0 nM
CCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(O[C@@H]3CCN(c4ccc(OC[C@H]5CC5(F)F)cn4)C3)cc2)s1 CHEMBL3639855 IC50 93.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N(C)C4CC4)ncc3Cl)C2)cc1 CHEMBL3662468 IC50 93.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CN(c3ccc(OCC4CC4(F)F)cn3)C[C@H]2F)cc1 CHEMBL3686586 IC50 94.0 nM
CCC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(O[C@@H]3CCN(c4ncnc(NCC5CC5)c4Cl)C3)cc2)s1 CHEMBL3667164 IC50 94.0 nM
CCNC(=O)Nc1sc2cc(C)ccc2c1C(=O)N1CCN(C2CCN(C(=O)C(C)(C)C(F)(F)F)CC2)CC1 CHEMBL1683796 IC50 95.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3cccc(C4CC4)n3)C2)cc1 CHEMBL3686531 IC50 95.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(OCCC(C)C)c3)C2)cc1 CHEMBL3691177 IC50 95.0 nM
C[C@H](NC(=O)C1CC1)c1ccc(O[C@@H]2CCN(c3ccnc(OC4CCC4)c3)C2)cc1 CHEMBL3691184 IC50 95.0 nM
CCN(C)c1ncc(F)c(N2CC[C@@H](Oc3ccc([C@H](C)NC(C)=O)cc3)C2)n1 CHEMBL3662357 IC50 95.0 nM
CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(c3ccnc(N(CC)CC)n3)C2)cc1 CHEMBL4109945 IC50 95.0 nM
CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(c3ncnc(OCC(C)(C)O)c3Cl)C2)cc1 CHEMBL4108419 IC50 95.0 nM
CC(=O)NC(C)c1ccc(CN2CCc3cc(OCCC(F)(F)F)ccc3C2)cc1 CHEMBL3901894 IC50 95.0 nM
C[C@H](NC(=O)Cc1cncnc1)c1ccc(CN2Cc3ccc(OCC4CC4(F)F)cc3C(F)C2)cc1 CHEMBL3959069 IC50 95.0 nM
CC(=O)N[C@@H](C)COc1cnc(-c2ccc(Oc3cccc(OCC4CC4)c3)cc2)o1 CHEMBL4085633 IC50 95.0 nM
COC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 CHEMBL426325 IC50 96.0 nM
COc1c(OCC2CC2)ncnc1N1CCC(Oc2ccc([C@H](C)NC(=O)c3sc(NC(C)=O)nc3C)cc2)C1 CHEMBL3658156 IC50 96.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3nc(N4CCC(F)(F)CC4)ncc3F)C2)cc1 CHEMBL3667122 IC50 96.0 nM
CC(C)n1ncc2c1C(=O)NC1(CCN(C(=O)C3=CC4C(Cl)=CNC4N=C3)CC1)C2 CHEMBL3699857 IC50 96.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N(C)C)c3F)C2)cc1 CHEMBL3691246 IC50 97.0 nM
COc1c(OC(C)C)ncnc1N1CC[C@@H](Oc2ccc([C@H](C)NC(C)=O)cc2)C1 CHEMBL3662310 IC50 97.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(N4CCC(F)(F)CC4)c3F)C2)cc1 CHEMBL3667112 IC50 97.0 nM
CC(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)C3=CC4C=NNC4C=C3)CC1)C2 CHEMBL3699865 IC50 97.0 nM
CC(=O)N[C@@H](C)c1ccc(OC2CCN(c3cc4c(cc3F)OCCCO4)C2)cc1 CHEMBL3938748 IC50 97.0 nM
CC(=O)Nc1nc(C)c(C(=O)N[C@@H](C)c2ccc(CN3CCc4c(cccc4OC4CCC4)C3)cc2)s1 CHEMBL3947064 IC50 97.0 nM
Cc1cc(C(=O)N2CCC3(CC2)CC(=O)c2c(ccnc2OCC(C)C)O3)cc2cn[nH]c12 CHEMBL1090180 IC50 98.0 nM
COCCc1cccc(Oc2ccc(-c3ccc(C(C)NC(C)=O)cc3)cc2)c1 CHEMBL4756960 IC50 98.0 nM
CC(C)(C)OC(=O)NC[C@H]1CC[C@H](CNC(=O)c2cc(N3CCC(CCN4CC(O)C4)CC3)nc3ccccc23)CC1 CHEMBL1818300 IC50 99.0 nM
C[C@H](NC(=O)c1ccon1)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 CHEMBL3686710 IC50 99.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ncnc(OC[C@H]4CC4(F)F)c3F)C2)cc1 CHEMBL3662305 IC50 99.0 nM
CC(=O)N[C@@H](C)c1ccc(O[C@@H]2CCN(c3ccnc(N4CCC(F)(F)CC4)n3)C2)cc1 CHEMBL3667068 IC50 99.0 nM