C[C@@]1(O)CCCN(S(=O)(=O)c2ccc(OCc3ccc(F)cc3Cl)cc2)[C@H]1C(=O)NO CHEMBL187092 IC50 1.0 nM
C[C@H](Cc1ccc(C(F)(F)F)cc1)C(=O)NC[C@@]1(C2CC2)NC(=O)NC1=O CHEMBL4066965 IC50 1.0 nM
CC1(C)C[C@@H](O)CN(S(=O)(=O)c2ccc(OCc3ccc(Cl)cc3Cl)cc2)[C@H]1C(=O)NO CHEMBL179552 IC50 1.4 nM
CC[C@H](Cc1ccc(C(F)(F)F)cc1)C(=O)NC[C@@]1(C2CC2)NC(=O)NC1=O CHEMBL4072836 IC50 2.0 nM
O=C1NC(=O)[C@](CNC(=O)[C@@H](Cc2ccc(C(F)(F)F)cc2)C2CC2)(C2CC2)N1 CHEMBL3980860 IC50 2.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1cc2[nH]c3cc(Cl)ccc3c2s1)C(=O)O CHEMBL1766903 IC50 2.9 nM
Cn1ccnc1[C@]1(CNC(=O)c2cc3cc(Cl)ccc3o2)NC(=O)NC1=O CHEMBL3358156 IC50 3.0 nM
Cc1cnc([C@]2(CNC(=O)c3cc4cc(C(F)(F)F)ccc4o3)NC(=O)NC2=O)n1C CHEMBL4436740 IC50 3.0 nM
Cn1ccnc1[C@]1(CNC(=O)c2cc3cc(C(F)(F)F)ccc3o2)NC(=O)NC1=O CHEMBL3358158 IC50 4.0 nM
CC(C)(Cc1ccc(C(F)(F)F)cc1)C(=O)NC[C@@]1(C2CC2)NC(=O)NC1=O CHEMBL3972836 IC50 4.0 nM
CCn1ccnc1[C@]1(CNC(=O)c2cc3cc(C(F)(F)F)ccc3o2)NC(=O)NC1=O CHEMBL4450729 IC50 4.0 nM
O=C(CCc1ccc(C(F)(F)F)cc1)NC[C@@]1(C2CC2)NC(=O)NC1=O CHEMBL4102193 IC50 5.0 nM
O=C1NC(=O)[C@](CNC(=O)c2cc3cc(C(F)(F)F)ccc3o2)(C2CC2)N1 CHEMBL4097165 IC50 5.0 nM
Cc1cnc([C@]2(CNC(=O)c3cc4cc(Cl)ccc4o3)NC(=O)NC2=O)n1C CHEMBL4587825 IC50 7.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1ccc(-n2cc(Cl)cn2)s1)C(=O)O CHEMBL1078281 IC50 7.4 nM
CC(C)[C@H](Cc1ccc(C(F)(F)F)cc1)C(=O)NC[C@@]1(C2CC2)NC(=O)NC1=O CHEMBL3955404 IC50 8.0 nM
CC1[C@](C)(c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(nc3cc(F)ccn23)C1)C(=O)O CHEMBL4864283 IC50 8.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1cc2[nH]c3cc(F)ccc3c2s1)C(=O)O CHEMBL1766904 IC50 8.3 nM
C[C@@H]1[C@](C)(c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(nc3cc(F)ccn23)C1)C(=O)O CHEMBL1767014 IC50 8.4 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(nn3cc(F)ccc23)C1)C(=O)O CHEMBL1767011 IC50 8.6 nM
CCn1ccnc1[C@]1(CNC(=O)c2cc3cc(Cl)ccc3o2)NC(=O)NC1=O CHEMBL4589438 IC50 9.0 nM
C[C@]1(c2ccccc2)C[C@@]1(NS(=O)(=O)c1ccc(-c2ccc(Cl)cc2)s1)C(=O)O CHEMBL1078454 IC50 10.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1cc2[nH]c3ccc(F)cc3c2s1)C(=O)O CHEMBL1766905 IC50 10.0 nM
C[C@@H]1[C@](C)(c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(nn3cc(F)ccc23)C1)C(=O)O CHEMBL1767015 IC50 10.0 nM
Cc1cc(F)ccc1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCN(C(=O)C3CCC3)CC2)CC1 CHEMBL1784336 IC50 11.0 nM
O=C(NO)[C@@H](NCC1CC1)[C@@H](Cc1cccc(O)c1)C(=O)N[C@H]1c2ccccc2C[C@H]1O CHEMBL24398 IC50 12.0 nM
C[C@@H](C[C@@]1(C2CC2)NC(=O)NC1=O)C(=O)N1CCN(c2ccc(F)c(F)c2)[C@@H](C)C1 CHEMBL4874034 IC50 12.0 nM
Cc1ccccc1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCN(C(=O)C3CCC3)CC2)CC1 CHEMBL1784337 IC50 13.0 nM
C[C@@H](Cc1ccc(C(F)(F)F)cc1)C(=O)NC[C@@]1(C2CC2)NC(=O)NC1=O CHEMBL4094455 IC50 13.0 nM
C[C@@H]1[C@](C)(c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(nc3cc(F)ccc32)C1)C(=O)O CHEMBL1767013 IC50 14.0 nM
COc1cnn(-c2ccc(S(=O)(=O)N[C@@]3(C(=O)O)[C@H](C)[C@@H]3c3ccccc3)s2)c1 CHEMBL1766899 IC50 17.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(nc3cc(F)ccn23)C1)C(=O)O CHEMBL1767010 IC50 17.0 nM
C[C@@H]1CN(S(=O)(=O)N[C@@]2(C(=O)O)[C@H](C)[C@]2(C)c2ccccc2)CCN1c1cc(C(F)F)on1 CHEMBL1767017 IC50 17.0 nM
O=C1NC(=O)[C@](CNC(=O)c2cc3cc(Cl)ccc3o2)(c2nccs2)N1 CHEMBL3358155 IC50 17.0 nM
CC1(CC(CO)C(=O)N2CCN(c3cc(Cl)cc(Cl)c3)CC2)NC(=O)NC1=O CHEMBL4846457 IC50 18.0 nM
Cc1cnn(-c2ccc(S(=O)(=O)N[C@@]3(C(=O)O)[C@H](C)[C@@H]3c3ccccc3)s2)c1 CHEMBL1766900 IC50 19.0 nM
Cc1cccnc1[C@]1(CNC(=O)c2cc3cc(Cl)ccc3o2)NC(=O)NC1=O CHEMBL3358154 IC50 19.0 nM
Cn1nccc1[C@]1(CNC(=O)c2cc3cc(Cl)ccc3o2)NC(=O)NC1=O CHEMBL3358157 IC50 19.0 nM
C[C@H]1CN(C(=O)CC[C@@]2(C3CC3)NC(=O)NC2=O)CCN1c1cc(F)cc(F)c1 CHEMBL4650334 IC50 19.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(nc3cc(F)ccc32)C1)C(=O)O CHEMBL1767005 IC50 20.0 nM
Cc1cc(Cl)ccc1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCN(C(=O)C3CCC3)CC2)CC1 CHEMBL1784369 IC50 20.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1ccc(-c2ccc(Cl)cc2)s1)C(=O)O CHEMBL1078279 IC50 21.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(nc3cc(Cl)ccn23)C1)C(=O)O CHEMBL1766921 IC50 21.0 nM
O=C1NC(=O)[C@](CNC(=O)c2cc3cc(Cl)ccc3o2)(c2ccccc2)N1 CHEMBL3358153 IC50 22.0 nM
CC(CC1(C)NC(=O)NC1=O)C(=O)N1CCN(c2cc(Cl)cc(Cl)c2)CC1 CHEMBL4856943 IC50 22.0 nM
COCC(CC1(C)NC(=O)NC1=O)C(=O)N1CCN(c2cc(Cl)cc(Cl)c2)CC1 CHEMBL4868710 IC50 22.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1cc2nc3cc(Cl)ccn3c2s1)C(=O)O CHEMBL1766901 IC50 23.0 nM
Cc1noc(C)c1CCC1CCN(S(=O)(=O)C[C@](C)(C[C@H](C)c2ncc(F)cn2)N(O)C=O)CC1 CHEMBL1615187 IC50 23.0 nM
C[C@@H]1CN(S(=O)(=O)N[C@@]2(C(=O)O)[C@H](C)[C@@H]2c2ccccc2)CCN1c1cc(C(F)F)on1 CHEMBL1766916 IC50 27.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1cc2nn3cc(Cl)ccc3c2s1)C(=O)O CHEMBL1766902 IC50 29.0 nM
C[C@@H]1CN(S(=O)(=O)N[C@@]2(C(=O)O)[C@H](C)[C@]2(C)c2ccccc2)CCN1c1ccc(C#N)s1 CHEMBL1767016 IC50 29.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3cc(Cl)cc(Cl)c3)CC2)(C2CC2)N1 CHEMBL4864100 IC50 29.0 nM
CCCNc1nc(NCc2cn(C)cn2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(CCC)cc2)n1 CHEMBL2164094 IC50 30.0 nM
C=CCCNc1nc(NCc2csc(-c3cccs3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(CCC)cc2)n1 CHEMBL2164121 IC50 30.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3cc(Cl)cc(Cl)c3)CC2)(c2ccccn2)N1 CHEMBL4874226 IC50 30.0 nM
CCCNc1nc(NCc2nccn2C)nc(N2CCCC2CNS(=O)(=O)c2ccc(CCC)cc2)n1 CHEMBL4853676 IC50 30.0 nM
Cc1ccccc1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCOCC2)CC1 CHEMBL1784363 IC50 31.0 nM
C[C@]1(c2ccccc2)C[C@@]1(NS(=O)(=O)c1ccc(-n2cc(Cl)cn2)s1)C(=O)O CHEMBL1078280 IC50 32.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3cccc(Cl)c3)CC2)(c2cccnc2)N1 CHEMBL4872817 IC50 32.0 nM
C[C@@H]1CN(S(=O)(=O)N[C@@]2(C(=O)O)[C@H](C)[C@@H]2c2ccccc2)CCN1c1ccc(C#N)s1 CHEMBL1766915 IC50 33.0 nM
Cc1ccc(Cl)cc1N1CCN(C(=O)CCC2(C3CC3)NC(=O)NC2=O)CC1 CHEMBL4854306 IC50 34.0 nM
C[C@H]1CN(C(=O)CCC2(C3CC3)NC(=O)NC2=O)CCN1c1cc(Cl)cc(Cl)c1 CHEMBL4854866 IC50 34.0 nM
O=C(CNS(=O)(=O)c1ccc(OCc2ccc(F)cc2Cl)cc1)NO CHEMBL2337698 IC50 35.0 nM
C[C@@H]1CN(S(=O)(=O)N[C@@]2(C(=O)O)[C@H](C)[C@@H]2c2ccccc2)CCN1c1ccc(Cl)cc1 CHEMBL1766908 IC50 37.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c([nH]c3cc(F)ccc23)C1)C(=O)O CHEMBL1767012 IC50 38.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(cc3cc(Cl)ccc32)C1)C(=O)O CHEMBL1766919 IC50 39.0 nM
C=CCCNc1nc(NCc2csc(-c3cccs3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc3ccccc3c2)n1 CHEMBL2164122 IC50 40.0 nM
CC(C)(Cc1ccc(F)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)c1ccc(-c2ccccc2)cc1 CHEMBL4859268 IC50 40.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3cccc(Cl)c3)CC2)(C2CC2)N1 CHEMBL4877087 IC50 41.0 nM
C[C@H]1CN(C(=O)CC[C@@]2(C)NC(=O)NC2=O)CCN1c1ccc(Cl)c(Cl)c1 CHEMBL4859812 IC50 43.0 nM
C[C@H]1CN(C(=O)CCC2(c3ccccn3)NC(=O)NC2=O)CCN1c1cc(Cl)cc(Cl)c1 CHEMBL4863614 IC50 46.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN(c2ccc(Cl)cc2)[C@@H](C)C1)C(=O)O CHEMBL1766909 IC50 47.0 nM
C[C@H]1CN(C(=O)CCC2(c3ccccn3)NC(=O)NC2=O)CCN1c1ccc(F)c(Cl)c1 CHEMBL4876618 IC50 47.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3ccc(F)c(Cl)c3)CC2)(c2ccccn2)N1 CHEMBL4862188 IC50 48.0 nM
C=CCCNc1nc(NCc2csc(-c3ccccc3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(OC)cc2)n1 CHEMBL2163735 IC50 50.0 nM
CCCNc1nc(NCc2csc(-c3ccccc3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(CCC)cc2)n1 CHEMBL2164107 IC50 50.0 nM
C=CCCNc1nc(NCc2csc(-c3cccs3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(C(F)(F)F)cc2)n1 CHEMBL2164120 IC50 50.0 nM
C[C@H]1CN(C(=O)CCC2(C3CC3)NC(=O)NC2=O)CCN1c1cccc(Cl)c1 CHEMBL4856883 IC50 52.0 nM
CC(C)C(CC1(C)NC(=O)NC1=O)C(=O)N1CCN(c2cc(Cl)cc(Cl)c2)CC1 CHEMBL4877662 IC50 55.0 nM
O=C(O)[C@]1(NS(=O)(=O)c2ccc(-c3ccc(Cl)cc3)s2)C[C@@H]1c1ccccc1 CHEMBL1078167 IC50 60.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(nc3cc(Cl)ccc32)C1)C(=O)O CHEMBL1766920 IC50 60.0 nM
C=CCCNc1nc(NCc2csc(-c3ccccc3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(C(F)(F)F)cc2)n1 CHEMBL2164117 IC50 60.0 nM
O=CN(O)C1(CS(=O)(=O)N2CCC(CCc3ccc(F)cc3C(F)(F)F)CC2)CCN(C(=O)C2CCC2)CC1 CHEMBL1784370 IC50 61.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CC=C(c2ccc(Cl)cc2)CC1)C(=O)O CHEMBL1766907 IC50 62.0 nM
Cc1cc(Cl)ccc1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCOCC2)CC1 CHEMBL1784358 IC50 65.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1Cc2nc3cc(Cl)ccn3c2C1)C(=O)O CHEMBL1767003 IC50 66.0 nM
COCc1cc(N2CCN(S(=O)(=O)N[C@@]3(C(=O)O)[C@H](C)[C@@H]3c3ccccc3)C[C@H]2C)no1 CHEMBL1766918 IC50 67.0 nM
Cc1cc(F)ccc1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCOCC2)CC1 CHEMBL1784339 IC50 69.0 nM
CCCc1ccc(S(=O)(=O)NC[C@H]2CCCN2c2nc(NCc3csc(-c4ccccc4)n3)nc(NC3CC3)n2)cc1 CHEMBL2164111 IC50 70.0 nM
O=C(O)[C@@]1(N(CCn2cnc3ncncc32)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL500030 IC50 71.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3cccc(Cl)c3)CC2)(c2ccccc2)N1 CHEMBL4846698 IC50 71.0 nM
COC(=O)c1cn(CCN([C@]2(C(=O)O)C[C@H]2c2ccccc2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)cn1 CHEMBL448604 IC50 73.0 nM
COc1cccn(CCN([C@]2(C(=O)O)C[C@H]2c2ccccc2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)c1=O CHEMBL474069 IC50 78.0 nM
Cc1cc(C(F)(F)F)ccc1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCN(C(=O)C3CCC3)CC2)CC1 CHEMBL1784371 IC50 79.0 nM
O=C(O)[C@]1(NS(=O)(=O)c2ccc(-n3cc(Cl)cn3)s2)C[C@@H]1c1ccccc1 CHEMBL1077893 IC50 80.0 nM
O=C(O)[C@]1(NS(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@@H]1c1ccccc1 CHEMBL1079173 IC50 84.0 nM
Cc1ccccc1N1CCN(C(=O)CC[C@@]2(c3ccccc3)NC(=O)NC2=O)CC1 CHEMBL4850150 IC50 84.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN(c2ccc(Cl)cc2)CC1)C(=O)O CHEMBL1766906 IC50 87.0 nM
CCCc1ccc(S(=O)(=O)NC[C@H]2CCCN2c2nc(NCCC#N)nc(NCc3csc(-c4ccccc4)n3)n2)cc1 CHEMBL2164113 IC50 90.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(nc3ccccc32)C1)C(=O)O CHEMBL1767004 IC50 92.0 nM
O=C(C[C@@H](Cc1cccc(O)c1)C(=O)N[C@H]1c2ccccc2C[C@H]1O)NO CHEMBL8943 IC50 93.0 nM
O=C(O)[C@]1(NS(=O)(=O)c2ccc(-c3cccc(Cl)c3)s2)C[C@@H]1c1ccccc1 CHEMBL1078168 IC50 94.0 nM
Cc1cc(COc2ccc(C(=O)NC3(CC(=O)NO)CCNCC3)cc2)c2ccccc2n1 CHEMBL208009 Ki 97.0 nM
O=C(O)[C@]1(NS(=O)(=O)c2ccc(-c3ccc(Cl)cn3)s2)C[C@@H]1c1ccccc1 CHEMBL1077892 IC50 100.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(nc3ccc(F)cc32)C1)C(=O)O CHEMBL1767006 IC50 100.0 nM
O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 CHEMBL297453 IC50 100.0 nM
O=C(O[C@@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1)c1cc(O)c(O)c(O)c1 CHEMBL36327 IC50 100.0 nM
O=C1NC(=O)C(CCC(=O)N2CCC(c3ccccc3)CC2)(C2CC2)N1 CHEMBL4856230 IC50 109.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(cc3cc(Cl)sc32)C1)C(=O)O CHEMBL1766922 IC50 110.0 nM
O=S(=O)(NC[C@H]1CCCN1c1nc(NCc2csc(-c3cccs3)n2)nc(NCC2CC2)n1)c1ccc(C(F)(F)F)cc1 CHEMBL2164103 IC50 110.0 nM
C[C@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1ccc(-c2ccc(Cl)cc2)s1)C(=O)O CHEMBL1077579 IC50 120.0 nM
CCCc1ccc(S(=O)(=O)NC[C@H]2CCCN2c2nc(NCc3csc(-c4ccccc4)n3)nc(NCC(C)C)n2)cc1 CHEMBL2164109 IC50 120.0 nM
CC(C)C1(CCC(=O)N2CCN(c3cccc(Cl)c3)CC2)NC(=O)NC1=O CHEMBL4849855 IC50 123.0 nM
O=C1NC(=O)C(CCC(=O)N2CCC(c3cc(Cl)cc(Cl)c3)CC2)(C2CC2)N1 CHEMBL4872381 IC50 124.0 nM
C[C@@H]1CN(S(=O)(=O)N[C@@]2(C(=O)O)[C@H](C)[C@@H]2c2ccccc2)CCN1c1cc(C(C)(F)F)on1 CHEMBL1766917 IC50 130.0 nM
C[C@]1(CNC(=O)c2cc3cc(Cl)ccc3o2)NC(=O)NC1=O CHEMBL3358152 IC50 150.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3ccc(Cl)c(Cl)c3)CC2)N1 CHEMBL4856188 IC50 156.0 nM
CC1(CCC(=O)N2CCN(c3cc(Cl)cc(Cl)c3)CC2)NC(=O)NC1=O CHEMBL4876864 IC50 164.0 nM
O=C(O)[C@@]1(N(CCn2cnc3cncnc32)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL443680 IC50 170.0 nM
O=C(COc1ccc(Cl)cc1)NNC(=S)NCCCCC1CCCCC1 CHEMBL2437163 IC50 170.0 nM
CCCC1S/C(=C/c2nc3ccccc3[nH]2)NC1=O CHEMBL3104658 IC50 170.0 nM
O=C1NC(=O)[C@@H](CCC(=O)N2CCN(c3cc(Cl)cc(Cl)c3)CC2)N1 CHEMBL4873384 IC50 173.0 nM
C[C@H]1CN(C(=O)CCC2(C3CC3)NC(=O)NC2=O)CCN1c1ccccc1 CHEMBL4863647 IC50 178.0 nM
O=C1OCCCN1CCN([C@]1(C(=O)O)C[C@H]1c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2)cc1 CHEMBL477853 IC50 180.0 nM
O=C(O)[C@@]1(N(CCn2cncn2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL476835 IC50 180.0 nM
C[C@@H]1CN(S(=O)(=O)N[C@@]2(C(=O)O)[C@H](C)[C@@H]2c2ccccc2)CCN1c1ccc(F)cc1 CHEMBL1766913 IC50 180.0 nM
O=C(O)[C@@]1(N(CCn2cnnc2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL477040 IC50 190.0 nM
O=C1CCCN1CCN([C@]1(C(=O)O)C[C@H]1c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2)cc1 CHEMBL476667 IC50 200.0 nM
O=C1CCCCN1CCN([C@]1(C(=O)O)C[C@H]1c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2)cc1 CHEMBL477648 IC50 210.0 nM
O=C(O)[C@@]1(NS(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL1079172 IC50 210.0 nM
CCCc1ccc(S(=O)(=O)NC[C@H]2CCCN2c2nc(NCCOC)nc(NCc3csc(-c4ccccc4)n3)n2)cc1 CHEMBL2164115 IC50 210.0 nM
O=C1OCCN1CCN([C@]1(C(=O)O)C[C@H]1c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2)cc1 CHEMBL477647 IC50 220.0 nM
COC(=O)c1cncn1CCN([C@]1(C(=O)O)C[C@H]1c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2)cc1 CHEMBL460533 IC50 230.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN(c2ccc(Cl)cc2)C(CO)C1)C(=O)O CHEMBL1766912 IC50 230.0 nM
C=CCCNc1nc(NCc2csc(-c3ccccc3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccccc2)n1 CHEMBL2163736 IC50 230.0 nM
O=C(O)CCc1sc(/C=C2\NC(=O)CS2)nc1-c1ccccn1 CHEMBL2348091 IC50 230.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3cc(Cl)cc(Cl)c3)CC2)N1 CHEMBL4870697 IC50 230.0 nM
CCCCNc1nc(NCc2csc(-c3cccs3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(C(F)(F)F)cc2)n1 CHEMBL2164449 IC50 240.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3cccc(Cl)c3)CC2)(C2CCC2)N1 CHEMBL4867911 IC50 247.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(nc3cc(C#N)ccc32)C1)C(=O)O CHEMBL1767007 IC50 250.0 nM
Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCOC(C)(C)C2)CC1 CHEMBL1784350 IC50 250.0 nM
Cc1ccccc1N1CCN(C(=O)CCC2(c3ccccc3)NC(=O)NC2=O)CC1 CHEMBL4870479 IC50 251.0 nM
O=C(O)[C@@]1(N(CCn2nccn2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL476439 IC50 260.0 nM
CCCc1ccc(S(=O)(=O)NC[C@H]2CCCN2c2nc(NCCO)nc(NCc3csc(-c4ccccc4)n3)n2)cc1 CHEMBL2164114 IC50 260.0 nM
O=C(O)[C@@]1(N(CCn2ccnn2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL515463 IC50 270.0 nM
O=C(O)[C@@]1(N(CCn2cnnn2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL476640 IC50 270.0 nM
C[C@@H]1CN(S(=O)(=O)N[C@@]2(C(=O)O)[C@H](C)[C@@H]2c2ccccc2)CCN1c1ccc(C2CC2)cc1 CHEMBL2448145 IC50 270.0 nM
Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCN(C(=O)C3CCC3)CC2)CC1 CHEMBL1784345 IC50 270.0 nM
Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCS(=O)(=O)CC2)CC1 CHEMBL1784347 IC50 270.0 nM
CC1(CCC(=O)N2CCN(c3cccc(Cl)c3)CC2)NC(=O)NC1=O CHEMBL4878543 IC50 287.0 nM
O=C(O)[C@@]1(N(CCc2cccnc2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL476827 IC50 290.0 nM
O=C(Cc1ccc(-c2ccccc2)cc1)NNC(=S)NCCCCC1CCCCC1 CHEMBL2437157 IC50 300.0 nM
O=C1CCC(=O)N1CCN([C@]1(C(=O)O)C[C@H]1c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2)cc1 CHEMBL514387 IC50 310.0 nM
Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCN(S(C)(=O)=O)CC2)CC1 CHEMBL1784342 IC50 310.0 nM
O=C(O)[C@@]1(N(CCn2ccnc2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL477965 IC50 320.0 nM
Cc1ccc2c(c1)nc1n2CCN(S(=O)(=O)N[C@@]2(C(=O)O)[C@H](C)[C@@H]2c2ccccc2)C1 CHEMBL1767008 IC50 320.0 nM
C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN(c2ccc(Cl)cc2)C(C)(C)C1)C(=O)O CHEMBL1766911 IC50 330.0 nM
COc1ccc2c(c1)nc1n2CCN(S(=O)(=O)N[C@@]2(C(=O)O)[C@H](C)[C@@H]2c2ccccc2)C1 CHEMBL1767009 IC50 330.0 nM
O=C(CNS(=O)(=O)c1ccc(Oc2ccccc2)cc1)NO CHEMBL198778 IC50 330.0 nM
O=C(Cc1nc(-c2ccccc2)no1)NNC(=S)NCCCCC1CCCCC1 CHEMBL2437156 IC50 340.0 nM
O=C(COc1ccccc1)NC(c1ccccc1Cl)c1cc(Cl)c2cccnc2c1O CHEMBL481894 IC50 350.0 nM
C[C@]1(CNC(=O)COc2ccc(Cl)cc2)NC(=O)NC1=O CHEMBL3358151 IC50 350.0 nM
O=C(O)[C@]1(NS(=O)(=O)c2ccc(-n3cc(Cl)cn3)s2)C[C@@H]1C1CCCCC1 CHEMBL1078625 IC50 360.0 nM
CCCC1S/C(=C/c2nc3ccc(F)cc3[nH]2)NC1=O CHEMBL3104666 IC50 380.0 nM
CNc1nc(NCc2csc(-c3cccs3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(C(F)(F)F)cc2)n1 CHEMBL2164104 IC50 390.0 nM
O=C(O)Cc1sc(/C=C2\NC(=O)CS2)nc1-c1ccccn1 CHEMBL2348077 IC50 400.0 nM
CCC1CN(S(=O)(=O)N[C@@]2(C(=O)O)[C@H](C)[C@@H]2c2ccccc2)CCN1c1ccc(Cl)cc1 CHEMBL1766910 IC50 410.0 nM
Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCC(F)(F)CC2)CC1 CHEMBL1784346 IC50 410.0 nM
CCCCNc1nc(NCc2cccc(C)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(CCC)cc2)n1 CHEMBL2164092 IC50 410.0 nM
CCCCC1S/C(=C/c2nc3ccccc3[nH]2)NC1=O CHEMBL3104659 IC50 410.0 nM
O=C(NO)C1(S(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CCN(Cc2ccccc2)CC1 CHEMBL79433 IC50 420.0 nM
O=C(O)CCc1sc(/C=C2\NC(=O)CS2)nc1-c1sccc1Br CHEMBL2348090 IC50 420.0 nM
O=C(O)CCc1sc(/C=C2\NC(=O)CS2)nc1-c1ccccc1 CHEMBL2348087 IC50 420.0 nM
CCC1S/C(=C/c2nc3ccccc3[nH]2)NC1=O CHEMBL3104657 IC50 420.0 nM
C=CCCNc1nc(NCc2csc(C)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(C(F)(F)F)cc2)n1 CHEMBL2164087 IC50 430.0 nM
O=C(O)CCc1sc(/C=C2\NC(=O)CS2)nc1-c1ccc(-c2ccccc2)cc1 CHEMBL2348089 IC50 430.0 nM
O=C(O)Cc1sc(/C=C2\NC(=O)CS2)nc1-c1ccc(-c2ccccc2)cc1 CHEMBL2348073 IC50 430.0 nM
O=C(O)CC1S/C(=C/c2nc3ccccc3[nH]2)NC1=O CHEMBL3104660 IC50 430.0 nM
Cc1nsc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCOCC2)CC1 CHEMBL1784366 IC50 450.0 nM
O=C(COc1ccccc1)NC(c1ccc([N+](=O)[O-])cc1)c1cc(Cl)c2cccnc2c1O CHEMBL482160 IC50 460.0 nM
CCCCNc1nc(NCc2csc(-c3cccs3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(Cl)cc2)n1 CHEMBL2163738 IC50 460.0 nM
O=C(O)Cc1sc(/C=C2\NC(=O)CS2)nc1-c1sccc1Br CHEMBL2348076 IC50 470.0 nM
O=C1CS/C(=C/c2nc3ccccc3[nH]2)N1 CHEMBL3104673 IC50 470.0 nM
O=C1CS/C(=C/c2nc(-c3ccccn3)cs2)N1 CHEMBL3104667 IC50 470.0 nM
Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCN(C(=O)N3CCC3)CC2)CC1 CHEMBL1784341 IC50 480.0 nM
O=C1N/C(=C\c2nc3ccccc3[nH]2)SC1CCO CHEMBL3104661 IC50 480.0 nM
CC1S/C(=C/c2nc3ccccc3[nH]2)NC1=O CHEMBL3104650 IC50 480.0 nM
O=C(COc1ccccc1)NC(c1cccc([N+](=O)[O-])c1)c1cc(Cl)c2cccnc2c1O CHEMBL480567 IC50 490.0 nM
O=C(COc1ccc(Cl)cc1)NNC(=S)NCc1ccccc1-c1ccccc1 CHEMBL2437170 IC50 490.0 nM
CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CC(=O)NO)CC(C)C CHEMBL19611 IC50 500.0 nM
O=C(O)CCCc1sc(/C=C2\NC(=O)CS2)nc1-c1ccccc1 CHEMBL2348088 IC50 500.0 nM
CCCC1S/C(=C/c2nc3cccc(C)c3[nH]2)NC1=O CHEMBL3104662 IC50 500.0 nM
O=C1CS/C(=C/c2nc3c(s2)CSc2ccccc2-3)N1 CHEMBL3104649 IC50 500.0 nM
Cc1cc(S(C)(=O)=O)ccc1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCOCC2)CC1 CHEMBL1784360 IC50 530.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3ccc(Cl)cc3)CC2)N1 CHEMBL4876898 IC50 536.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3cccc(F)c3)CC2)N1 CHEMBL4868229 IC50 536.0 nM
O=C(COc1ccc(C(F)(F)F)cc1)NNC(=S)NCCCCC1CCCCC1 CHEMBL2437164 IC50 540.0 nM
Cc1cccnc1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCOCC2)CC1 CHEMBL1784364 IC50 580.0 nM
Cc1ccc(C2=NNC3(S2)C(=O)N(Cc2ccccc2)c2ccc(C)cc23)cc1 CHEMBL237148 IC50 610.0 nM
O=C(COc1ccccc1)NC(c1cccc(F)c1)c1cc(Cl)c2cccnc2c1O CHEMBL482170 IC50 620.0 nM
O=C(COc1ccccc1)NC(c1cccc([N+](=O)[O-])c1)c1cc(Br)c2cccnc2c1O CHEMBL481896 IC50 620.0 nM
O=C(CNS(=O)(=O)c1ccc(OCc2ccccc2)cc1)NO CHEMBL2337691 IC50 620.0 nM
Cc1ccncc1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCOCC2)CC1 CHEMBL1784361 IC50 630.0 nM
O=C(O)CCc1sc(/C=C2\NC(=O)CS2)nc1-c1ccc(Br)cn1 CHEMBL2348092 IC50 630.0 nM
O=C1NC(=O)C(CCC(=O)N2CCCN(c3ccccc3)CC2)(c2ccccc2)N1 CHEMBL4856611 IC50 638.0 nM
COc1ccc(C2=NNC3(S2)C(=O)N(Cc2ccccc2)c2ccc(C)cc23)cc1 CHEMBL401435 IC50 640.0 nM
O=C1NC(=O)C(CCC(=O)N2CCN(c3cccc(Cl)c3)CC2)N1 CHEMBL4872734 IC50 667.0 nM
O=C(NNC(=S)NCCCCC1CCCCC1)c1ccc(Cl)cc1 CHEMBL2437153 IC50 670.0 nM
Cc1ccc(C(NC(=O)COCc2ccccc2)c2cc(Cl)c3cccnc3c2O)cc1 CHEMBL480188 IC50 700.0 nM
CCCCNc1nc(NCc2csc(-c3cccs3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2cccc(Cl)c2)n1 CHEMBL2164078 IC50 700.0 nM
O=C(NNC(=S)NCc1ccc(-c2ccccc2)cc1)c1ccc(Cl)cc1 CHEMBL2437173 IC50 700.0 nM
O=C1CS/C(=C/c2nc3c(s2)CCc2ccccc2-3)N1 CHEMBL3104676 IC50 700.0 nM
CCCCNc1nc(NCc2csc(-c3cccs3)n2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(C)c(C)c2)n1 CHEMBL2164079 IC50 720.0 nM
Cc1ccc(-c2nc(/C=C3\NC(=O)CS3)sc2CC(=O)O)cc1 CHEMBL2348071 IC50 720.0 nM
CC(C(=O)O)c1sc(/C=C2\NC(=O)CS2)nc1-c1ccccc1 CHEMBL2348086 IC50 730.0 nM
O=C(O)[C@@]1(N(CCc2ccncc2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL515272 IC50 750.0 nM
Cc1ccc(C(NC(=O)COc2ccccc2)c2cc(Cl)c3cccnc3c2O)cc1 CHEMBL474607 IC50 760.0 nM
COc1ccc(C(NC(=O)COc2ccc(C)cc2)c2cc(Cl)c3cccnc3c2O)cc1 CHEMBL472143 IC50 770.0 nM
CC(C)[C@H]1C[C@@]1(NS(=O)(=O)c1ccc(-n2cc(Cl)cn2)s1)C(=O)O CHEMBL1078624 IC50 770.0 nM
CCCc1ccc2c(c1)NC(=O)C21NN=C(c2ccc(OC)cc2)S1 CHEMBL236523 IC50 780.0 nM
O=C(COc1ccccc1)NC(c1ccccc1)c1cc(Cl)c2cccnc2c1O CHEMBL482073 IC50 780.0 nM
Cc1ccc(C(NC(=O)CN(C)c2ccccc2)c2cc(Cl)c3cccnc3c2O)cc1 CHEMBL473637 IC50 780.0 nM
O=C(COc1ccccc1)NC(c1ccccc1Cl)c1cc(Br)c2cccnc2c1O CHEMBL514963 IC50 800.0 nM
C[C@@H]1[C@H](C)[C@]1(NS(=O)(=O)c1ccc(-n2cc(Cl)cn2)s1)C(=O)O CHEMBL1078322 IC50 800.0 nM
COc1cc(Cc2nnc([C@H](CCC(=O)O)NC(=O)c3ccc(-c4ccccc4)cc3)o2)cc(OC)c1OC CHEMBL1807399 IC50 800.0 nM
O=C(COc1ccc([N+](=O)[O-])cc1)NNC(=S)NCCCCC1CCCCC1 CHEMBL2437160 IC50 810.0 nM
O=C(O)[C@@]1(N(CCc2ccccn2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)C[C@H]1c1ccccc1 CHEMBL514669 IC50 820.0 nM
CN(CC(=O)NC(c1cccc([N+](=O)[O-])c1)c1cc(Cl)c2cccnc2c1O)Cc1ccccc1 CHEMBL473842 IC50 820.0 nM
CC(=O)N1CCC(CS(=O)(=O)N2CCC(CCc3c(C)noc3C)CC2)(N(O)C=O)CC1 CHEMBL1784348 IC50 820.0 nM
CC1(CCC(=O)N2CCN(c3ccccc3)CC2)NC(=O)NC1=O CHEMBL4859417 IC50 826.0 nM
O=C(COc1ccccc1)NC(c1ccc(Cl)cc1)c1cc(Cl)c2cccnc2c1O CHEMBL481506 IC50 830.0 nM
O=C(COc1ccccc1)NC(c1ccccc1C(F)(F)F)c1cc(Cl)c2cccnc2c1O CHEMBL482362 IC50 830.0 nM
O=C(COCc1ccccc1)NC(c1cccc(F)c1)c1cc(Cl)c2cccnc2c1O CHEMBL482171 IC50 830.0 nM
CC(C)c1sc(/C=C2\NC(=O)CS2)nc1-c1ccccc1 CHEMBL2348082 IC50 830.0 nM
O=C(O)Cc1sc(/C=C2\NC(=O)CS2)nc1-c1ccc(Br)cn1 CHEMBL2348078 IC50 840.0 nM
Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCCCC2)CC1 CHEMBL1784353 IC50 850.0 nM
Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCOCC2)CC1 CHEMBL1784340 IC50 860.0 nM
COc1ccc(C2=NNC3(S2)C(=O)N(Cc2ccccc2)c2ccccc23)cc1 CHEMBL237149 IC50 870.0 nM
C=CCCNc1nc(NCc2ccccc2)nc(N2CCC[C@@H]2CNS(=O)(=O)c2ccc(C(F)(F)F)cc2)n1 CHEMBL2164088 IC50 870.0 nM
O=C1CCCN1CCN([C@]1(C(=O)O)C[C@H]1c1ccccc1)S(=O)(=O)N1CC=C(c2ccc(Cl)cc2)CC1 CHEMBL478127 IC50 880.0 nM
O=C(COc1cccc2ccccc12)NNC(=S)NCCCCC1CCCCC1 CHEMBL2437159 IC50 880.0 nM
O=C(O)C(c1ccccc1)N1C(=O)/C(=C\c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)SC1=S CHEMBL387994 IC50 900.0 nM
COc1ccc(C2=NNC3(S2)C(=O)N(c2ccccc2C)c2ccc(C)cc23)cc1 CHEMBL237366 IC50 900.0 nM
COc1cccc(N2CCN(C(=O)CCC3NC(=O)NC3=O)CC2)c1 CHEMBL4851316 IC50 903.0 nM
O=C(COc1ccccc1)NC(c1ccccc1Cl)c1cc([N+](=O)[O-])c2cccnc2c1O CHEMBL475265 IC50 940.0 nM
COc1ccc(OCC(=O)NC(c2ccc(OC)cc2)c2cc(Cl)c3cccnc3c2O)cc1 CHEMBL472144 IC50 940.0 nM
CCCc1cc2c(cc1C)C1(NN=C(c3ccc(OC)cc3)S1)C(=O)N2Cc1ccccc1 CHEMBL237368 IC50 950.0 nM
O=C(NO)c1nc2ccccc2c2c1CN(c1ccc(OCc3ccccc3)cc1)C2=O CHEMBL1766896 IC50 950.0 nM
CS(=O)(=O)c1ccc(CCC2CCN(S(=O)(=O)CC3(N(O)C=O)CCOCC3)CC2)c(C2CC2)c1 CHEMBL1784359 IC50 950.0 nM
CN(CC(=O)NC(c1ccccc1Cl)c1cc(Cl)c2cccnc2c1O)c1ccccc1 CHEMBL475436 IC50 990.0 nM
O=C(N[C@@H]1CCOC[C@@H]1C(=O)NO)c1ccc(Cn2c(C(F)(F)F)nc3ccccc32)cc1 CHEMBL253275 Ki 1000.0 nM
COc1ccc(C(NC(=O)COc2ccccc2)c2cc(Cl)c3cccnc3c2O)cc1 CHEMBL481505 IC50 1000.0 nM
COc1ccc(-c2nc(/C=C3\NC(=O)CS3)sc2CC(=O)O)cc1 CHEMBL2348072 IC50 1000.0 nM
O=C(COc1ccc(Cl)cc1)NNC(=S)NCCCCc1ccccc1 CHEMBL2437165 IC50 1000.0 nM
O=C(COc1ccc(OCc2ccccc2)cc1)NNC(=S)NCc1ccc(-c2ccccc2)cc1 CHEMBL2437180 IC50 1000.0 nM