Nc1ncnc2c1c(I)nn2[C@@H]1C[C@H](N)[C@@H](O)[C@H]1O CHEMBL4460859 IC50 0.06 nM
NC[C@H]1O[C@@H](n2cc(I)c3c(Cl)ncnc32)[C@H](O)[C@@H]1O CHEMBL330432 IC50 0.1 nM
NC[C@H]1O[C@@H](n2cc(Br)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL99707 IC50 0.2 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC(=O)Nc4ccc(Cl)cc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL370164 IC50 0.2 nM
O[C@H]1[C@H](n2cc(-c3ccccc3)c3c(Nc4ccc(F)cc4)ncnc32)OC2(CC2)[C@H]1O CHEMBL194294 IC50 0.3 nM
Nc1ncnc(C#Cc2ccc(N3CCOCC3)nc2)c1-c1cc2ccccc2s1 CHEMBL226486 IC50 0.4 nM
OC[C@@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL343247 IC50 0.47 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL100421 IC50 0.5 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NC/C(S)=N\C4CC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL370011 IC50 0.5 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC(=O)Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL426472 IC50 0.5 nM
NC[C@H]1O[C@@H](n2cc(I)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL322611 IC50 0.6 nM
O=C(CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1OC[C@@H](O)[C@H]1O)Nc1ccccc1 CHEMBL200169 IC50 0.6 nM
OC[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL319315 IC50 0.8 nM
C[C@@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL436598 IC50 0.8 nM
CNC(=O)CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL200630 IC50 0.8 nM
O=C(CNc1ncnc2c1c(-c1ccccc1)nn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)Nc1ccccc1 CHEMBL198566 IC50 0.9 nM
C[C@H]1O[C@@H](n2cc(I)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL66280 IC50 0.9 nM
C[C@H]1O[C@@H](n2c(Br)c(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL328826 IC50 1.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccc(O)cc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL98551 IC50 1.0 nM
COc1ccc(-c2cn([C@@H]3O[C@H](C)[C@@H](O)[C@H]3O)c3ncnc(Nc4ccc(C#N)cc4)c23)cc1 CHEMBL317603 IC50 1.0 nM
c1ccc(CN2C[C@@H]3CCCN(c4ncnc5oc(-c6ccccc6)nc45)[C@@H]3C2)cc1 CHEMBL174158 IC50 1.0 nM
Cc1ccccc1-c1cn([C@@H]2OC[C@@H](O)[C@H]2O)c2ncnc(Nc3ccc4c(c3)OCCO4)c12 CHEMBL370218 IC50 1.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC(=O)NC4CCCC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL438449 IC50 1.0 nM
Nc1ncnc(C#Cc2ccc(N3CCOCC3)nc2)c1-c1cc2ccccc2o1 CHEMBL449402 IC50 1.0 nM
CC(=O)N1CCN(c2ccc(C#Cc3ncnc(N)c3-c3ccc(Cl)cc3)cn2)CC1 CHEMBL225729 IC50 1.0 nM
COCCN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccc(Cl)cc2)cn1 CHEMBL225672 IC50 1.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccc(Cl)cc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL318918 IC50 1.2 nM
Nc1ncnc2nc(-c3ccc(N4CCOCC4)nc3)cc(-c3cccc(Br)c3)c12 CHEMBL66089 IC50 1.3 nM
Nc1ncnc2nc(-c3ccc(N4CCSCC4)nc3)cc(-c3cccc(Br)c3)c12 CHEMBL62576 IC50 1.3 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NC(=O)C(=O)NC4CC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL372796 IC50 1.3 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC(=O)NC4CCC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL370654 IC50 1.3 nM
Nc1ncnc2nc(-c3ccc(N4CCC5(CC4)OCCO5)nc3)cc(-c3cccc(Br)c3)c12 CHEMBL65665 IC50 1.4 nM
Cc1ccc(Nc2ncnc3c2c(-c2ccccc2)cn3[C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)cc1 CHEMBL318929 IC50 1.5 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccc(F)cc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL66277 IC50 1.5 nM
[N-]=[N+]=NC[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL98867 IC50 1.5 nM
OC[C@@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccc(F)cc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL344529 IC50 1.5 nM
c1ccc(CN2CC[C@H]3CN(c4ncnc5oc(-c6ccccc6)nc45)C[C@H]32)cc1 CHEMBL360273 IC50 1.5 nM
Nc1ncnc2nc(-c3ccc(N4CCC(O)CC4)nc3)cc(-c3cccc(Br)c3)c12 CHEMBL62974 IC50 1.8 nM
CCOc1cccc(Nc2ncnc3c2c(-c2ccccc2)cn3[C@@H]2OC[C@@H](O)[C@H]2O)c1 CHEMBL371704 IC50 2.0 nM
CCOc1ccc(-c2cn([C@@H]3OC[C@@H](O)[C@H]3O)c3ncnc(Nc4ccc(C#N)cc4)c23)cc1 CHEMBL435120 IC50 2.0 nM
COCCCNC(=O)CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL200575 IC50 2.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC(N)=O)ncnc32)[C@H](O)[C@@H]1O CHEMBL197112 IC50 2.0 nM
CN(C)c1ccc(-c2c(N)ncnc2C#Cc2ccc(N3CCOCC3)nc2)cc1 CHEMBL216697 IC50 2.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccc(Cl)cc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL317818 IC50 2.3 nM
Nc1ncnc(C#Cc2ccc(N3CCOCC3)nc2)c1CCCc1ccccc1 CHEMBL338508 IC50 2.5 nM
C[C@H]1O[C@@H](n2cc(-c3ccc(Cl)cc3)c3c(Nc4ccc(Cl)cc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL432062 IC50 2.7 nM
Nc1ncnc2nc(-c3ccc(N4CCC(COC5CCOCC5)CC4)nn3)cc(-c3cccc(Br)c3)c12 CHEMBL101805 IC50 2.8 nM
OC[C@@H]1O[C@@H](n2nc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL141327 IC50 2.8 nM
C[C@H]1O[C@@H](n2cc(I)c3c(Cl)ncnc32)[C@H](O)[C@@H]1O CHEMBL329724 IC50 3.0 nM
CCOc1ccc(Nc2ncnc3c2c(-c2ccccc2)cn3[C@@H]2OC[C@@H](O)[C@H]2O)cc1 CHEMBL197756 IC50 3.0 nM
O=C(CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)NC1CC1 CHEMBL198635 IC50 3.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC(=O)NC4CC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL371909 IC50 3.0 nM
Nc1ncnc(C#Cc2ccc(N3CCOCC3)nc2)c1-c1ccc(Cl)cc1 CHEMBL225671 IC50 3.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccc(Br)cc2)cc1 CHEMBL225695 IC50 3.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccc(Cl)cc2)cc1 CHEMBL225633 IC50 3.0 nM
Nc1ncnc2nc(-c3ccc(N4CCCC4)nc3)cc(-c3cccc(Br)c3)c12 CHEMBL302404 IC50 3.4 nM
C[C@H]1O[C@@H](n2cc(-c3ccco3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL99565 IC50 3.6 nM
Nc1ncnc2nc(-c3cccs3)c(Cc3cccc(Br)c3)cc12 CHEMBL191309 IC50 3.8 nM
NC[C@H]1O[C@@H](n2nc(Br)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL356141 IC50 4.0 nM
O[C@@H]1[C@H](O)CO[C@H]1n1cc(-c2ccccc2)c2c(Nc3ccccc3)ncnc21 CHEMBL373218 IC50 4.0 nM
O[C@@H]1[C@H](O)CO[C@H]1n1cc(-c2ccccc2)c2c(Nc3ccc4c(c3)OCCO4)ncnc21 CHEMBL364049 IC50 4.0 nM
CC(C)CNC(=O)CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL371044 IC50 4.0 nM
CCCOC(=O)Nc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL435123 IC50 4.0 nM
CN(Cc1cccnc1)c1ccc(-c2cc(-c3cccc(Br)c3)c3c(N)ncnc3n2)cn1 CHEMBL62524 IC50 4.1 nM
CO[C@@H]1CCCN1c1ccc(-c2cc(-c3cccc(Br)c3)c3c(N)ncnc3n2)cn1 CHEMBL62342 IC50 4.12 nM
O[C@@H]1[C@H](O)CO[C@H]1n1cc(-c2ccccc2)c2c(Nc3ccc(Br)cc3)ncnc21 CHEMBL381682 IC50 5.0 nM
CCONC(=O)CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL438796 IC50 5.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccc(N(C)C)cc2)cc1 CHEMBL226392 IC50 5.0 nM
CCOc1ccc(-c2cn([C@@H]3OC[C@@H](O)[C@H]3O)c3ncnc(Nc4ccccc4OC)c23)cc1 CHEMBL196483 IC50 5.3 nM
COc1ccc(Nc2ncnc3c2c(-c2ccccc2)cn3[C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)cc1 CHEMBL98744 IC50 6.0 nM
Nc1ncnc2c1c(I)cn2[C@@H]1OC[C@@H](O)[C@H]1O CHEMBL194952 IC50 6.0 nM
O[C@@H]1[C@H](O)CO[C@H]1n1cc(-c2ccccc2)c2c(Nc3ccc(F)cc3)ncnc21 CHEMBL197801 IC50 6.0 nM
C[C@H]1O[C@@H](n2nc(-c3ccccc3)c3c(NCC(=O)NC4CC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL436096 IC50 6.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC(=O)NCC4CC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL381229 IC50 6.0 nM
CN(C)S(=O)(=O)N1CCN(c2ccc(C#Cc3ncnc(N)c3-c3ccc(Cl)cc3)cn2)CC1 CHEMBL225727 IC50 6.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccc(Cl)cc2)cn1 CHEMBL225670 IC50 6.0 nM
CN(C)c1ccc(C#Cc2ncnc(N3CCOCC3)c2-c2ccc(Cl)cc2)cc1 CHEMBL387630 IC50 6.0 nM
NC[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL99829 IC50 6.3 nM
Nc1ncnc2nc(-c3ccc(N4C[C@@H](O)[C@@H](O)C4)nc3)cc(-c3cccc(Br)c3)c12 CHEMBL105216 IC50 6.5 nM
N#Cc1ccc(Nc2ncnc3c2c(-c2ccc(Cl)cc2)cn3[C@@H]2OC[C@@H](O)[C@H]2O)cc1 CHEMBL198143 IC50 7.0 nM
CCCNC(=O)CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL200219 IC50 7.0 nM
Nc1ncnc2nc(-c3ccc(N4CCC(=NOC5CCOCC5)CC4)nn3)cc(-c3cccc(Br)c3)c12 CHEMBL103812 IC50 7.1 nM
CCO[C@H]1CN(c2ccc(-c3cc(-c4cccc(Br)c4)c4c(N)ncnc4n3)nn2)C[C@H]1OCC CHEMBL102989 IC50 7.2 nM
N#C[C@H]1CN(c2ccc(-c3cc(-c4cccc(Br)c4)c4c(N)ncnc4n3)cn2)C[C@H]1O CHEMBL319197 IC50 7.5 nM
Nc1ncnc2nc(-c3ccc(N4CC5CC4CO5)nc3)cc(-c3cccc(Br)c3)c12 CHEMBL104983 IC50 7.5 nM
CN(C)c1ccc(C#Cc2ncnc3c2c(-c2cccc(Br)c2)nn3C)cn1 CHEMBL185372 IC50 7.5 nM
Nc1ncnc2nc(-c3ccc(N4CCC(=NOC5CCOCC5)CC4)nc3)cc(-c3cccc(Br)c3)c12 CHEMBL65664 IC50 8.0 nM
COc1ccc(-c2cc3c(N)ncnc3nc2-c2cccs2)cc1Br CHEMBL372666 IC50 8.0 nM
Nc1ncnc(C#Cc2cncc(N3CCOCC3)c2)c1-c1ccc(Cl)cc1 CHEMBL225886 IC50 8.0 nM
Nc1ncnc(C#Cc2cnc(N3CCOCC3)nc2)c1-c1ccc(Cl)cc1 CHEMBL438476 IC50 8.0 nM
CN(C)c1ccc(C#Cc2ncnc(N3CCNCC3)c2-c2ccc(Cl)cc2)cc1 CHEMBL226504 IC50 8.0 nM
Nc1ncnc2nc(-c3ccc(N4CCC(O)(C5CCOC5=O)CC4)nc3)cc(-c3cccc(Br)c3)c12 CHEMBL103909 IC50 8.1 nM
Nc1ncnc2nc(-c3ccc(N4CCC5(CC4)COCO5)nc3)cc(-c3cccc(Br)c3)c12 CHEMBL102712 IC50 8.3 nM
[N-]=[N+]=NC[C@H]1O[C@@H](n2cc(I)c3c(Cl)ncnc32)[C@H](O)[C@@H]1O CHEMBL449407 IC50 9.0 nM
COc1ccc(Nc2ncnc3c2c(-c2ccco2)cn3[C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)cc1 CHEMBL99025 IC50 9.0 nM
Cc1ccc(-c2cc3c(N)ncnc3nc2-c2cccs2)cc1 CHEMBL193286 IC50 9.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccc3c(c2)OCO3)cc1 CHEMBL386316 IC50 9.0 nM
Nc1ncnc(C#Cc2ccc(N3CCCCC3)nc2)c1-c1ccc(Cl)cc1 CHEMBL225781 IC50 9.0 nM
Nc1ncnc2nc(-c3ccc(N4CCOCC4)nc3)cc(NCc3c[nH]c4ccccc34)c12 CHEMBL116872 IC50 10.0 nM
CN(C)c1ccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)cn1 CHEMBL366539 IC50 10.0 nM
Nc1cccc(-c2cn([C@@H]3OC[C@@H](O)[C@H]3O)c3ncnc(Nc4ccc(F)cc4)c23)c1 CHEMBL380998 IC50 10.0 nM
O=C(CNc1ncnc2c1c(-c1ccccc1)nn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)NC1CC1 CHEMBL200457 IC50 10.0 nM
Nc1ncnc(C#Cc2ccc(N3CCOCC3)nc2)c1-c1ccc2c(c1)OCO2 CHEMBL375255 IC50 10.0 nM
Nc1ccc(C#Cc2ncnc(N)c2-c2ccc(Cl)cc2)cc1 CHEMBL387486 IC50 10.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2-c2cccc(Cl)c2)cc1 CHEMBL389409 IC50 10.0 nM
CCOC1CCN(c2ccc(-c3cc(-c4cccc(Br)c4)c4c(N)ncnc4n3)nn2)CC1 CHEMBL106386 IC50 10.4 nM
CCCCc1cc2c(N)ncnc2nc1-c1cccs1 CHEMBL193253 IC50 11.0 nM
Nc1ncnc(C#Cc2ccc(N3CCOCC3)nc2)c1-c1cccs1 CHEMBL225782 IC50 13.0 nM
Cc1ccc(-c2c(N)ncnc2C#Cc2ccc(N(C)C)cc2)cc1 CHEMBL225696 IC50 13.0 nM
CN(C)c1ccc(C#Cc2ncnc(N3CCN(S(=O)(=O)N(C)C)CC3)c2-c2ccc(Cl)cc2)cc1 CHEMBL226505 IC50 13.0 nM
C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1cccc(C(C)(C)O)n1 CHEMBL1976040 Kd apparent 13.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccc(C#N)cc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL318645 IC50 14.0 nM
Nc1ccc(C#Cc2ncnc(N)c2-c2ccc(Cl)cc2)cn1 CHEMBL225887 IC50 14.0 nM
CNc1ncnc(C#Cc2ccc(N(C)C)cc2)c1-c1ccc(Cl)cc1 CHEMBL427272 IC50 14.0 nM
COC[C@@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL358584 IC50 15.0 nM
COCCOC1CCN(c2ccc(-c3cc(-c4cccc(Br)c4)c4c(N)ncnc4n3)nn2)CC1 CHEMBL103729 IC50 15.1 nM
NC[C@@H]1O[C@@H](n2cc(I)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL144936 IC50 16.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC(=O)NCCCO)ncnc32)[C@H](O)[C@@H]1O CHEMBL197072 IC50 16.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2-c2cccc([N+](=O)[O-])c2)cc1 CHEMBL375294 IC50 16.0 nM
Nc1ncnc2nc(-c3ccc(N4CCC[C@H]4CO)nn3)cc(-c3cccc(Br)c3)c12 CHEMBL319412 IC50 16.2 nM
Nc1ncnc2c1c(I)cn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL99203 Ki 16.3 nM
Nc1ncnc(C#Cc2ccc(N3CCOCC3)cc2)c1-c1ccc(Cl)cc1 CHEMBL225833 IC50 17.0 nM
CC(C)NC(=O)Nc1cc(C#Cc2ncnc(N)c2-c2ccc3c(c2)OCO3)cnc1N1CCOCC1 CHEMBL225679 IC50 18.0 nM
COc1ccc(-c2c(N)ncnc2C#Cc2ccc(N(C)C)cc2)cc1 CHEMBL388192 IC50 18.0 nM
CON=C1CCN(c2ccc(-c3cc(-c4cccc(Br)c4)c4c(N)ncnc4n3)nn2)CC1 CHEMBL102524 IC50 18.8 nM
OC[C@H]1O[C@@H](n2c(Nc3ccccc3)nc3c(N4CCc5ccccc54)ncnc32)[C@H](O)[C@@H]1O CHEMBL364496 IC50 19.0 nM
CN(C)c1ccc(-c2nc3ncnc(N)c3cc2-c2ccc(Br)cc2)cc1 CHEMBL191161 IC50 20.0 nM
O=C(CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1OC[C@@H](O)[C@H]1O)NC1CC1 CHEMBL200196 IC50 20.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccccc2)cc1 CHEMBL216119 IC50 20.0 nM
COc1ccc(-c2c(N)ncnc2C#Cc2ccc(N(C)C)cc2)cc1OC CHEMBL226515 IC50 20.0 nM
Brc1cccc(-c2[nH]nc3ncnc(C#Cc4ccc(N5CCOCC5)nc4)c23)c1 CHEMBL183535 IC50 22.0 nM
Nc1ncnc(C#Cc2ccc(N3CCOCC3)nc2)c1Cc1cccc(Br)c1 CHEMBL120650 IC50 22.0 nM
CC(C)c1ccc(-c2c(N)ncnc2C#Cc2ccc(N(C)C)cc2)cc1 CHEMBL225705 IC50 22.0 nM
Nc1ncnc2nc(-c3ccc(N4CCC(CCOC5CCOCC5)CC4)nn3)cc(-c3cccc(Br)c3)c12 CHEMBL317711 IC50 22.8 nM
Nc1ncnc2nc(-c3ccc(N4CCOCC4)nc3)cc(NCCc3c[nH]c4ccccc34)c12 CHEMBL356339 IC50 23.0 nM
OC[C@H]1O[C@@H](n2cc(I)c3c(Cl)ncnc32)[C@H](O)[C@@H]1O CHEMBL328824 IC50 24.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4cccnc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL99536 IC50 25.0 nM
COc1ccc(-c2c(-c3cccs3)nc3ncnc(N)c3c2-c2cc(Br)cs2)cc1OC CHEMBL150478 IC50 25.0 nM
CC(C)NC(=O)CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL425752 IC50 25.0 nM
Cc1ccc(C#Cc2ncnc(N)c2-c2ccc(Cl)cc2)cc1 CHEMBL390827 IC50 25.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccc(F)cc3)c3c(Nc4ccc(F)cc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL100262 IC50 26.0 nM
CN(C)c1cc(C#Cc2ncnc(N)c2-c2ccc3c(c2)OCO3)cnc1N1CCOCC1 CHEMBL376844 IC50 26.0 nM
CNC(=O)Nc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL198972 IC50 27.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL316668 IC50 30.0 nM
O=C(Nc1ccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)cc1)C1CC1 CHEMBL174700 IC50 30.0 nM
CN(Cc1ccccc1)c1c(N)ncnc1C#Cc1ccc(N2CCOCC2)nc1 CHEMBL120976 IC50 30.0 nM
CCCCCc1cc2c(N)ncnc2nc1-c1ccc(N(C)C)cc1 CHEMBL189632 IC50 30.0 nM
C/C(=N/OC1CCOCC1)C1(O)CCN(c2ccc(-c3cc(-c4cccc(Br)c4)c4c(N)ncnc4n3)cn2)CC1 CHEMBL322448 IC50 31.7 nM
CN(C)c1ccc(-c2cc(-c3cccc(Br)c3)c3c(N)ncnc3n2)cn1 CHEMBL68748 IC50 32.0 nM
COc1ccc(-c2cc3c(N)ncnc3nc2-c2ccc(N(C)C)cc2)cc1Br CHEMBL192887 IC50 33.0 nM
[N-]=[N+]=NC[C@H]1O[C@@H](n2cc(I)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL318043 IC50 35.0 nM
NC[C@@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL422122 IC50 36.0 nM
COc1ccc(-c2cc3c(N)ncnc3nc2-c2cccs2)cc1OC CHEMBL189575 IC50 38.0 nM
COCCNC(=O)CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL371950 IC50 38.0 nM
Nc1ncnc(C#Cc2ccc(N3CCOCC3)nc2)c1-c1ccsc1 CHEMBL226428 IC50 38.0 nM
CN(C)c1ccc(C#Cc2ncnc(NCCc3c[nH]c4ccccc34)c2-c2ccc(Cl)cc2)cc1 CHEMBL226503 IC50 38.0 nM
Nc1ncnc2c1c(I)nn2C1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL608051 Ki 40.0 nM
C[C@H]1O[C@@H](n2cc(Br)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL98909 IC50 40.0 nM
COCC(=O)Nc1ccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)cc1 CHEMBL368401 IC50 40.0 nM
COCC(=O)Nc1cccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)c1 CHEMBL175074 IC50 40.0 nM
CCNC(=O)CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL381407 IC50 40.0 nM
Nc1ncnc(C#Cc2ccc(N3CCOCC3)nc2)c1Cc1ccccc1 CHEMBL420879 IC50 40.0 nM
Nc1ncnc2c1c(I)nn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL4441282 IC50 40.0 nM
NC[C@@H]1O[C@@H](n2nc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL356758 IC50 42.0 nM
Nc1ncnc(C#Cc2ccc([N+](=O)[O-])cc2)c1-c1ccc(Cl)cc1 CHEMBL225774 IC50 43.0 nM
Nc1ncnc(C#Cc2cccs2)c1-c1ccc(Cl)cc1 CHEMBL225773 IC50 43.0 nM
C[C@@H]1C[C@@H](O)[C@H](n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)O1 CHEMBL442002 IC50 44.0 nM
CSc1ncnc2c1c(I)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL95481 IC50 45.0 nM
COc1ccc(-c2cc3c(N)ncnc3nc2-c2ccc(N(C)C)cc2)cc1OC CHEMBL191679 IC50 45.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC4CC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL200620 IC50 45.0 nM
Nc1ncnc(C#Cc2ccc(N3CCOCC3)nn2)c1-c1ccc(Cl)cc1 CHEMBL225834 IC50 45.0 nM
Cc1nc(Nc2ccccc2)c2c(-c3ccccc3)cn([C@@H]3O[C@H](C)[C@@H](O)[C@H]3O)c2n1 CHEMBL99062 IC50 47.0 nM
Cc1ccc(-c2cc3c(N)ncnc3nc2-c2ccsc2)cc1 CHEMBL189161 IC50 47.0 nM
Nc1ncnc2nc(-c3cccs3)c(-c3ccccc3)c(-c3ccccc3)c12 CHEMBL348712 IC50 49.0 nM
C[C@H]1O[C@@H](n2cc(Br)c3c(Cl)ncnc32)[C@H](O)[C@@H]1O CHEMBL98910 IC50 50.0 nM
Nc1ccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)cc1 CHEMBL362464 IC50 50.0 nM
CC(C)c1ccc(C#Cc2ncnc(N)c2-c2ccc(Cl)cc2)cc1 CHEMBL225877 IC50 50.0 nM
Nc1ncnc2c1c(-c1cn[nH]c1)cn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL1814774 IC50 50.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(N4CCc5ccccc54)ncnc32)[C@H](O)[C@@H]1O CHEMBL189105 IC50 51.0 nM
CN(C)c1ccc(-c2nc3ncnc(N)c3c(-c3ccccc3)c2-c2ccccc2)cn1 CHEMBL151448 IC50 53.0 nM
CC[C@H]1O[C@@H](n2cc(I)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL97494 IC50 60.0 nM
O=C(Nc1cccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)c1)C1CC1 CHEMBL174992 IC50 60.0 nM
C=Cc1nc2c(N3CCc4ccccc43)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL362987 IC50 60.0 nM
O=C(CNc1ncnc2c1c(-c1ccccc1)cn2COCCO)Nc1ccc(Cl)cc1 CHEMBL199371 IC50 60.0 nM
Nc1ncnc(C#Cc2ccccc2)c1-c1ccc(Cl)cc1 CHEMBL225707 IC50 60.0 nM
CC(C)(C)OC(=O)N1CCN(c2ccc(C#Cc3ncnc(N)c3-c3ccc(Cl)cc3)cn2)CC1 CHEMBL225728 IC50 62.0 nM
[N-]=[N+]=NC[C@H]1O[C@@H](n2cc(Br)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL97437 IC50 63.0 nM
Nc1ncnc2c1c(I)cn2[C@@H]1O[C@@H](CO)[C@@H](O)[C@H]1O CHEMBL356952 IC50 68.0 nM
CSc1cn([C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)c2ncnc(Cl)c12 CHEMBL318056 IC50 70.0 nM
O=C(Nc1ccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)cc1)c1ccccc1 CHEMBL175041 IC50 70.0 nM
Clc1ccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)cn1 CHEMBL175440 IC50 70.0 nM
O=C(Cc1ccccc1)Nc1ccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)cc1 CHEMBL361797 IC50 70.0 nM
CN(C)c1ccc(-c2nc3ncnc(N)c3cc2-c2cccc(Br)c2)cc1 CHEMBL189576 IC50 70.0 nM
c1ccc(CCCNc2ncnc3nc(-c4ccc(N5CCOCC5)nc4)cnc23)cc1 CHEMBL182969 IC50 72.0 nM
CN(C)c1cc(N2CCOCC2)ncc1C#Cc1ncnc(N)c1-c1ccc2c(c1)OCO2 CHEMBL225678 IC50 72.0 nM
CN(C)c1ccc(C#Cc2[nH]cnc3nnc(-c4cccc(Br)c4)c2-3)cn1 CHEMBL183671 IC50 75.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccccc2Cl)cc1 CHEMBL225694 IC50 75.0 nM
CN(C)c1ccc(C#Cc2ncnc(NCCc3c[nH]cn3)c2-c2ccc(Cl)cc2)cc1 CHEMBL387629 IC50 80.0 nM
c1ccc(CCCCNc2ncnc3nc(-c4ccc(N5CCOCC5)nc4)cnc23)cc1 CHEMBL182321 IC50 82.0 nM
Cn1nc(-c2cccc(Br)c2)c2c(C#Cc3ccc(N4CCOCC4)nc3)ncnc21 CHEMBL181551 IC50 82.0 nM
C[C@@H]1[C@@H](O)[C@@H](O)[C@@]2(n3cc(-c4ccccc4)c4c(Nc5ccccc5)ncnc43)C[C@@H]12 CHEMBL4578381 IC50 88.0 nM
O=C(Nc1cccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)c1)c1ccccc1 CHEMBL424966 IC50 90.0 nM
c1ccc(CN2CCC3CN(c4ncnc5oc(-c6ccc(-c7cccs7)cc6)nc45)CC32)cc1 CHEMBL425500 IC50 90.0 nM
OC[C@H]1O[C@@H](n2c(Nc3ccccc3)nc3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL192504 IC50 90.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2-c2cccc(N)c2)cc1 CHEMBL225706 IC50 90.0 nM
COc1ccc(-c2cc3c(N)ncnc3nc2-c2ccc(N(C)C)cc2)cc1 CHEMBL302938 IC50 92.0 nM
C=C[C@H]1O[C@@H](n2cc(I)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL97553 IC50 100.0 nM
[N-]=[N+]=NC[C@H]1O[C@@H](n2cc(Br)c3c(Cl)ncnc32)[C@H](O)[C@@H]1O CHEMBL99119 IC50 100.0 nM
C[C@H]1O[C@@H](n2cc(I)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL318281 IC50 100.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)C[C@@H]1O CHEMBL319611 IC50 100.0 nM
CN(C)c1ccc(C#Cc2[nH]cnc3nnc(-c4ccccc4)c2-3)cn1 CHEMBL362855 IC50 100.0 nM
CCCNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL198742 IC50 100.0 nM
CN(C)c1ccc(C#Cc2c(N)ncnc2-c2ccc(N(C)C)cc2)cc1 CHEMBL387628 IC50 100.0 nM
COCCN(C)c1cc(N2CCOCC2)ncc1C#Cc1ncnc(N)c1-c1ccc2c(c1)OCO2 CHEMBL225680 IC50 101.0 nM
C[C@@H]1[C@@H](O)[C@@H](O)[C@@]2(n3cc(-c4ccccc4)c4c(Nc5ccc(F)cc5)ncnc43)C[C@@H]12 CHEMBL4570382 IC50 110.0 nM
CN(C)c1ccc(-c2nc3ncnc(N)c3cc2Cc2ccccc2)cc1 CHEMBL426992 IC50 114.0 nM
OC[C@@H]1[C@@H](O)[C@@H](O)[C@@]2(n3cc(-c4ccccc4)c4c(Nc5ccccc5)ncnc43)C[C@@H]12 CHEMBL4439949 IC50 114.0 nM
Cc1ccc(-c2cc3c(N)ncnc3nc2-c2ccc(/C=C/c3ccccn3)cc2)cc1 CHEMBL193122 IC50 115.0 nM
C[C@@H]1[C@@H](O)[C@@H](O)[C@@]2(n3cc(-c4ccc(F)cc4)c4c(Nc5ccccc5)ncnc43)C[C@@H]12 CHEMBL4560021 IC50 115.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL62099 IC50 120.0 nM
OC[C@H]1O[C@@H](n2cc(I)c3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL317176 IC50 120.0 nM
c1ccc(CN2CC[C@@H]3CN(c4ncnc5oc(-c6ccccc6)nc45)C[C@@H]32)cc1 CHEMBL175809 IC50 120.0 nM
c1ccc(CCNc2ncnc3nc(-c4ccc(N5CCOCC5)nc4)cnc23)cc1 CHEMBL359631 IC50 120.0 nM
Nc1cc(C#Cc2ccc(N3CCOCC3)nc2)ncn1 CHEMBL119839 IC50 120.0 nM
CN(C)c1ccc(-c2nc3ncnc(N)c3c(-c3cccc(Cl)c3)c2-c2ccccc2)cn1 CHEMBL422489 IC50 130.0 nM
CN(C)c1ccc(-c2c(-c3ccc(N4CCOCC4)nc3)nc3ncnc(N)c3c2-c2cccc(Cl)c2)cc1 CHEMBL358714 IC50 130.0 nM
O=C(Nc1ccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)cc1)c1ccc(F)cc1 CHEMBL366606 IC50 130.0 nM
c1ccc(CN2CCC3CN(c4ncnc5oc(-c6cccnc6)nc45)CC32)cc1 CHEMBL369761 IC50 130.0 nM
CC(C)CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL196955 IC50 140.0 nM
OC[C@@]12C[C@@H]1[C@@H](n1cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc31)[C@H](O)[C@@H]2O CHEMBL4552895 IC50 140.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC(=O)NCCCN(C)C)ncnc32)[C@H](O)[C@@H]1O CHEMBL382911 IC50 145.0 nM
NC[C@H]1OC(n2nc(I)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL607761 Ki 150.0 nM
CSc1nc2c(N3CCc4ccccc43)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL192903 IC50 150.0 nM
Nc1ncnc2nc(-c3ccc(N4CCOCC4)nc3)c(-c3ccccc3)c(-c3cccc(Br)c3)c12 CHEMBL151812 IC50 155.0 nM
Nc1ncnc2c1c(I)nn2C1O[C@H](CF)[C@@H](O)[C@H]1O CHEMBL607766 Ki 160.0 nM
COC(=O)Cc1c(-c2cccs2)nc2ncnc(N)c2c1-c1cccc(Br)c1 CHEMBL346622 IC50 163.0 nM
CN(C)c1ccc(-c2cc(-c3cccc(Br)c3)c3c(N)ncnc3n2)cc1 CHEMBL68749 IC50 167.0 nM
C[C@H]1OC(n2nc(I)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL612205 Ki 170.0 nM
NC[C@@H]1O[C@@H](n2nc(Br)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL342959 IC50 170.0 nM
NC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL302376 IC50 170.0 nM
Cc1ccc(-c2cc3c(N)ncnc3nc2-c2ccc(-c3cncnc3)cc2)cc1 CHEMBL371857 IC50 180.0 nM
CN(C)c1ccc(-c2cc3c(N)ncnc3nc2-c2ccc(N(C)C)cc2)cc1 CHEMBL189480 IC50 183.0 nM
Sc1nnc2c3c4c(sc3n3c(S)nnc3n12)CCCC4 CHEMBL4570031 Ki 184.0 nM
Nc1ncnc2nc(-c3ccc(N4CCOCC4)nc3)c(-c3ccc(F)cc3)c(-c3cccc(Br)c3)c12 CHEMBL151214 IC50 197.0 nM
C[C@H]1O[C@@H](n2cc(I)c3c(Nc4ccc(O)cc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL442003 IC50 200.0 nM
c1ccc(CN2CCC3CN(c4ncnc5oc(-c6ccccc6)nc45)CC32)cc1 CHEMBL177540 IC50 200.0 nM
O=C(Nc1cccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)c1)c1ccc(F)cc1 CHEMBL176718 IC50 200.0 nM
CC(C)Cc1cc2c(N)ncnc2nc1-c1ccc(N(C)C)cc1 CHEMBL190400 IC50 200.0 nM
C[C@H]1O[C@@H](n2c(Nc3ccccc3)nc3c(N4CCc5ccccc54)ncnc32)[C@H](O)[C@@H]1O CHEMBL193065 IC50 200.0 nM
C#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12 CHEMBL1814776 IC50 200.0 nM
Nc1ncnc2c1c(Cl)cn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL98933 IC50 210.0 nM
O=C(Cc1ccccc1)Nc1cccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)c1 CHEMBL369435 IC50 210.0 nM
CCN(CC)CCNC(=O)CNc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL198698 IC50 210.0 nM
Nc1ncnc(C#Cc2cncnc2)c1-c1ccc(Cl)cc1 CHEMBL375060 IC50 216.0 nM
c1ccc(CCCNc2ncnc3oc(-c4ccccc4)nc23)cc1 CHEMBL366694 IC50 230.0 nM
CCc1nc2c(N3CCc4ccccc43)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL371350 IC50 230.0 nM
C[C@@H](N)C(=O)NS(=O)(=O)OC[C@H]1O[C@@H](Cn2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL5283680 Ki 232.0 nM
Brc1ccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)cc1 CHEMBL355801 IC50 240.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NC4CCCCC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL98174 IC50 250.0 nM
CN(C)c1ccc(-c2nc3ncnc(N)c3c(-c3ccccc3)c2-c2ccccc2)cc1 CHEMBL356256 IC50 250.0 nM
Brc1cccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)c1 CHEMBL367498 IC50 260.0 nM
CN(CCCNc1ncnc2oc(-c3ccccc3)nc12)c1ccccc1 CHEMBL425507 IC50 270.0 nM
Nc1ncnc2c1c(Br)cn2[C@@H]1O[C@@H](CO)[C@@H](O)[C@H]1O CHEMBL141606 IC50 280.0 nM
Cc1ccc(-c2c(-c3cccs3)nc3ncnc(N)c3c2-c2ccc(C)c(F)c2)cc1F CHEMBL150370 IC50 288.0 nM
OC[C@H]1O[C@@H](n2cc(Cl)c3c(-c4ccco4)ncnc32)[C@H](O)[C@@H]1O CHEMBL585759 IC50 290.0 nM
Nc1ncnc2c1c(I)nn2C1O[C@H](CCl)[C@@H](O)[C@H]1O CHEMBL611890 Ki 300.0 nM
OC[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)C[C@@H]1O CHEMBL330221 IC50 300.0 nM
Nc1ncnc(N[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1[N+](=O)[O-] CHEMBL304179 Ki 300.0 nM
c1ccc2c(CCNc3ncnc4nc(-c5ccc(N6CCOCC6)nc5)cnc34)c[nH]c2c1 CHEMBL369112 IC50 300.0 nM
C=Cc1nc2c(Nc3ccccc3)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL189106 IC50 300.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC(=O)NCCN(C)C)ncnc32)[C@H](O)[C@@H]1O CHEMBL382451 IC50 300.0 nM
CN(C)c1ccc(C#Cc2ncnc(N(C)C)c2-c2ccc(Cl)cc2)cc1 CHEMBL226450 IC50 300.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2C2CCCCC2)cc1 CHEMBL376830 IC50 300.0 nM
OC[C@H]1O[C@@H](n2ccc3c(-c4cc5ccccc5s4)ncnc32)[C@H](O)[C@@H]1O CHEMBL3134389 IC50 300.0 nM
Cn1ccc2c1c1c(-c3cc4ccccc4o3)ncnc1n2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL4470770 IC50 300.0 nM
N#Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12 CHEMBL99668 IC50 310.0 nM
C[C@H]1O[C@@H](n2cc(C#N)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL99388 IC50 310.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL329484 IC50 320.0 nM
CN(C)c1ccc(-c2nc3ncnc(N)c3nc2-c2ccccc2)cc1 CHEMBL305746 IC50 333.0 nM
OC[C@H]1O[C@@H](n2c3ccoc3c3c(-c4cc5ccccc5o4)ncnc32)[C@H](O)[C@@H]1O CHEMBL4438098 IC50 336.0 nM
COc1ccc(-c2c(-c3ccc(N(C)C)cc3)nc3ncnc(N)c3c2-c2cccc(Br)c2)cc1OC CHEMBL342310 IC50 350.0 nM
CN(C)c1ccc(-c2nc3ncnc(N)c3cc2-c2ccccc2)cc1 CHEMBL150978 IC50 350.0 nM
COCCN(C)c1ccc(-c2nc3ncnc(N)c3c(-c3cc(Br)cs3)c2-c2ccc(OC)c(OC)c2)cc1 CHEMBL356896 IC50 367.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NC4CC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL381005 IC50 380.0 nM
C[C@@H]1O[C@@H](n2cc(I)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL145388 IC50 400.0 nM
OC[C@H]1O[C@@H](n2cnc3c(N4CCN(c5ccc(-c6cccc(CN7CCOCC7)c6)cc5)CC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL4442160 Ki 410.0 nM
CN(C)c1ccc(-c2nc3ncnc(N)c3cc2CCc2ccccc2)cc1 CHEMBL189971 IC50 433.0 nM
CN(C)c1ccc(-c2cnc3c(N)ncnc3n2)cc1 CHEMBL66338 IC50 440.0 nM
COC[C@H]1O[C@@H](n2cc(I)c3c(Cl)ncnc32)[C@H](O)[C@@H]1O CHEMBL99359 IC50 450.0 nM
Nc1ncnc2nc(-c3ccc(N4CCOCC4)nc3)c(Cc3ccccc3)c(-c3cccc(Br)c3)c12 CHEMBL439635 IC50 450.0 nM
C[C@H]1O[C@@H](n2cc(C(N)=O)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL98638 IC50 460.0 nM
Nc1ncnc2nc(-c3ccc(N4CCOCC4)nc3)cnc12 CHEMBL182654 IC50 460.0 nM
C[C@H]1O[C@@H](n2cc(-c3ccccc3)c3c(NCC(=O)N(C)C4CC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL372155 IC50 460.0 nM
CN(C)c1ccc(-c2cc(C3CCCCC3)c3c(N)ncnc3n2)cc1 CHEMBL302921 IC50 467.0 nM
CN(C)c1ccc(-c2cc(-c3ccccc3)c3c(N)ncnc3n2)cc1 CHEMBL68492 IC50 467.0 nM
CN(C)c1ccc(-c2cc3c(N)ncnc3nc2-c2ccncc2)cc1 CHEMBL193223 IC50 467.0 nM
NC(=O)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c12 CHEMBL101892 IC50 470.0 nM
Cn1ccc2c3c(-c4cc5ccccc5o4)ncnc3n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c21 CHEMBL4554008 IC50 470.0 nM
OC[C@H]1O[C@@H](n2c(Cl)nc3c(N4CCc5ccccc54)ncnc32)[C@H](O)[C@@H]1O CHEMBL193265 IC50 480.0 nM
CC[C@H]1O[C@@H](n2cc(Br)c3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL95721 IC50 500.0 nM
Cc1ccc(-c2cc3c(N)ncnc3nc2-c2ccc(N(C)C)cc2)cc1 CHEMBL66977 IC50 500.0 nM
OC[C@H]1O[C@@H](n2cnc3c(N4CCc5ccccc54)ncnc32)[C@H](O)[C@@H]1O CHEMBL191760 IC50 500.0 nM
Nc1ncnc(C#Cc2ccccn2)c1-c1ccc(Cl)cc1 CHEMBL225722 IC50 500.0 nM
C[C@H](Nc1ncnc2c1c(-c1ccccc1)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O)C(=O)NC1CC1 CHEMBL200393 IC50 530.0 nM
Cc1cn([C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)c2ncnc(Cl)c12 CHEMBL99662 IC50 535.0 nM
C[C@H]1O[C@@H](n2cc(I)c3c(Nc4ccc(F)cc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL431628 IC50 550.0 nM
Nc1ncnc2c1c(I)cn2[C@@H]1OC2(CC2)[C@@H](O)[C@H]1O CHEMBL373104 IC50 600.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2C(c2ccccc2)c2ccccc2)cc1 CHEMBL376831 IC50 600.0 nM
CN(C)c1ccc(-c2nc3ncnc(N)c3c(-c3cc(Br)cs3)c2C2CC2)cn1 CHEMBL265251 IC50 625.0 nM
CCCCCc1c(-c2ccc(N(C)C)nc2)nc2ncnc(N)c2c1-c1cccc(Br)c1 CHEMBL435646 IC50 625.0 nM
COC(=O)c1cccc(-c2cc3c(N)ncnc3nc2-c2ccc(N(C)C)cc2)c1 CHEMBL416498 IC50 700.0 nM
CN(C)c1ccc(-c2ccc3c(N)ncnc3n2)cc1 CHEMBL303499 IC50 773.0 nM
COc1ccc(Nc2ncnc3c2c(I)cn3[C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)cc1 CHEMBL98887 IC50 775.0 nM
C[C@H]1O[C@@H](n2cc(I)c3c(NCc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL317583 IC50 800.0 nM
C[C@H]1O[C@@H](n2cc(I)c3c(NCC(=O)NC4CC4)ncnc32)[C@H](O)[C@@H]1O CHEMBL200352 IC50 880.0 nM
Nc1ncnc2nc(-c3nccs3)c(Cc3cccc(Br)c3)cc12 CHEMBL364732 IC50 900.0 nM
CCOC(=O)c1cn([C@@H]2O[C@H](C)[C@@H](O)[C@H]2O)c2ncnc(N)c12 CHEMBL95256 IC50 1000.0 nM
Nc1ncnc2nc(-c3ccc(N4CCOCC4)cc3)cnc12 CHEMBL65852 IC50 1000.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@@H](CO)[C@@H](O)[C@H]1O CHEMBL145188 IC50 1000.0 nM
C[C@H]1O[C@@H](n2cc(I)c3c(SCc4ccccc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL419517 IC50 1000.0 nM
CCCCSc1ncnc2c1c(I)cn2[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O CHEMBL95211 IC50 1000.0 nM
OC[C@H]1O[C@@H](n2c(I)nc3c(N4CCc5ccccc54)ncnc32)[C@H](O)[C@@H]1O CHEMBL189781 IC50 1000.0 nM
CSc1nc2c(Nc3ccccc3)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL192727 IC50 1000.0 nM
C#Cc1nc2c(N3CCc4ccccc43)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL193175 IC50 1000.0 nM
CN(C)c1ccc(C#Cc2ncnc(N)c2Cc2ccccc2)cc1 CHEMBL226393 IC50 1000.0 nM
CCC1(c2ccc(CSc3ccccc3Cl)cc2)Oc2ccccc2-n2cccc2C1=O CHEMBL1688498 IC50 1000.0 nM
CCC1(c2ccc(CSc3ccc(F)cc3)cc2)Oc2ccccc2-n2cccc2C1=O CHEMBL1688504 IC50 1000.0 nM