CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(Br)cc5)CC4)cc3)[nH]c2c1=O CHEMBL4552275 Ki 0.0835 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccccc5Br)CC4)cc3)[nH]c2c1=O CHEMBL4450864 Ki 0.137 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(Br)c5)CC4)cc3)[nH]c2c1=O CHEMBL4464522 Ki 0.148 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(Br)cc5)CC4)cc3)[nH]c2c1=O CHEMBL4540206 Ki 0.153 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(C(F)(F)F)cc5)CC4)cc3)[nH]c2c1=O CHEMBL486478 Ki 0.157 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(I)cc5)CC4)cc3)[nH]c2c1=O CHEMBL4454481 Ki 0.159 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5cccc(F)c5)CC4)cc3)[nH]c2c1=O CHEMBL4466765 Kb 0.167 nM
[3H]C([3H])(CN1CCN(C(=O)c2cc3c(NCCNC(C)=O)nc(-c4ccccc4)nc3[nH]2)CC1)C([3H])([3H])c1ccccc1 CHEMBL500634 Kd 0.17 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCCCN4CCN(Cc5ccccc5Cl)CC4)cc3)nc2n(C)c1=O CHEMBL3121728 Ki 0.17 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(Cl)cc5)CC4)cc3)[nH]c2c1=O CHEMBL483261 Ki 0.215 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(Cl)c(OC)c5)CC4)cc3)[nH]c2c1=O CHEMBL4463929 Ki 0.215 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5cccc(Br)c5)CC4)cc3)[nH]c2c1=O CHEMBL4466625 Ki 0.234 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(N=[N+]=[N-])cc5)CC4)cc3)[nH]c2c1=O CHEMBL4567785 Ki 0.244 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(C(F)(F)F)c5)CC4)cc3)[nH]c2c1=O CHEMBL519390 Ki 0.281 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(C(F)(F)F)cc5)CC4)cc3)[nH]c2c1=O CHEMBL486479 Ki 0.303 nM
Nc1sc(-c2ccc(-c3cn(CCCCCCNc4ncnc5c4ncn5[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)nn3)cc2)c(-c2cccc(C(F)(F)F)c2)c1C(=O)c1ccccc1 CHEMBL5177040 pEC50 0.3236 nM
Nc1nc(NCCN2CCN(c3ccc(S(N)(=O)=O)cc3)CC2)nc2sc(-c3ccco3)nc12 CHEMBL4643397 IC50 0.34 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5cccc(Cl)c5)CC4)cc3)[nH]c2c1=O CHEMBL4460114 Ki 0.342 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(OC)c(Cl)c5)CC4)cc3)[nH]c2c1=O CHEMBL4530074 Ki 0.352 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(Cl)cc5)CC4)cc3)[nH]c2c1=O CHEMBL482436 Ki 0.393 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(C)c5)CC4)cc3)[nH]c2c1=O CHEMBL4440526 Ki 0.397 nM
CC[C@H](NC(=O)COc1ccc2[nH]c(=O)c(-c3nccs3)c(CCc3ccccc3)c2c1)c1ccccc1 CHEMBL1289569 Ki 0.4 nM
CC(=O)NCCNc1nc(-c2ccccc2)nc2[nH]c(C(=O)N3CCN(CCCc4ccccc4)CC3)cc12 CHEMBL485862 Ki 0.4 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(Cl)cc5)CC4)cc3)[nH]c2c1=O CHEMBL483688 Kd 0.403 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccccc5Cl)CC4)cc3)[nH]c2c1=O CHEMBL4441276 Ki 0.403 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(Cl)cc5)CC4)cc3)[nH]c2c1=O CHEMBL483487 Ki 0.406 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(Cl)c(O)c5)CC4)cc3)[nH]c2c1=O CHEMBL4454417 Ki 0.421 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccccc5C)CC4)cc3)[nH]c2c1=O CHEMBL4443090 Ki 0.432 nM
O=C(COc1ccc2[nH]c(=O)c(-c3nccs3)c(CCc3ccccc3)c2c1)N[C@@H](CO)c1ccccc1 CHEMBL1289676 Ki 0.44 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(F)c5)CC4)cc3)[nH]c2c1=O CHEMBL484900 Ki 0.446 nM
C#CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(Cl)cc5)CC4)cc3)[nH]c2c1=O CHEMBL519253 Ki 0.473 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(Br)c(F)c5)CC4)cc3)[nH]c2c1=O CHEMBL4566170 Ki 0.473 nM
CC(=O)NCCNc1nc(-c2ccccc2)nc2nc(C(=O)N3CCN(CCCc4ccccc4)CC3)[nH]c12 CHEMBL3786849 Ki 0.5 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(F)cc5)CC4)cc3)[nH]c2c1=O CHEMBL520830 Ki 0.595 nM
O=C(Nc1cnc(-c2ccncc2F)c(-c2ccccc2F)n1)C1CC1 CHEMBL1672631 Ki 0.6 nM
CC1=C(C(=O)OC(C)C)C(c2ccco2)n2c(nc3cc(Cl)ccc32)N1 CHEMBL5422322 KB 0.6 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(Cl)c5)CC4)cc3)[nH]c2c1=O CHEMBL482638 Ki 0.61 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5cccc(OC)c5)CC4)cc3)[nH]c2c1=O CHEMBL4456096 Ki 0.616 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(F)c(OC)c5)CC4)cc3)[nH]c2c1=O CHEMBL4464175 Ki 0.629 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccccc5)CC4)cc3)[nH]c2c1=O CHEMBL4572369 Ki 0.643 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(F)cc5)CC4)cc3)[nH]c2c1=O CHEMBL4471205 Ki 0.644 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(N=C=S)cc3)[nH]c2c1=O CHEMBL5207498 pKi 0.6607 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)F)cc3)[nH]c2c1=O CHEMBL5207290 pKi 0.6761 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(F)c5)CC4)cc3)[nH]c2c1=O CHEMBL484899 Ki 0.695 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(C)cc5)CC4)cc3)[nH]c2c1=O CHEMBL4464738 Ki 0.706 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(C(F)(F)F)c5)CC4)cc3)[nH]c2c1=O CHEMBL486688 Ki 0.775 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(Cl)c5)CC4)cc3)[nH]c2c1=O CHEMBL483469 Ki 0.782 nM
Cn1c(=O)c2[nH]c(-c3ccc(COC(=O)Nc4ccsc4)cc3)cc2n(C)c1=O CHEMBL513681 pKi 0.7943 nM
CC1=C(C(=O)OC(C)C)C(c2ccco2)n2c(nc3cc(F)ccc32)N1 CHEMBL5425672 KB 0.8 nM
COc1cccc2c1nc(N)n1nc(C3CCC(c4ccc(C(C)(C)N)cn4)C3)nc21 CHEMBL5426527 IC50 0.8 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(C)cc5)CC4)cc3)[nH]c2c1=O CHEMBL518972 Ki 0.858 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc6c(c5)OCO6)CC4)cc3)[nH]c2c1=O CHEMBL483065 Ki 0.875 nM
CC1=C(C(=O)OC(C)C)[C@@H](c2ccco2)n2c(nc3ccccc32)N1 CHEMBL5405410 Ki 0.89 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(OC)c(F)c5)CC4)cc3)[nH]c2c1=O CHEMBL4453324 Ki 0.894 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC(=O)N4CCN(c5ccc(C(F)(F)F)cc5)CC4)c3)nc2n(CCC)c1=O CHEMBL4068507 Ki 0.9 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5ccc(C(F)(F)F)cc5)C4)c3)nc2n(CCC)c1=O CHEMBL4083317 Ki 0.9 nM
CC1=C(C(=O)OC(C)C)[C@@H](c2ccco2)n2c(nc3cc(F)ccc32)N1 CHEMBL5417576 Ki 0.94 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(OC)cc5)CC4)cc3)[nH]c2c1=O CHEMBL482855 Ki 0.944 nM
CCCn1c(=O)c2nc(-c3cnn(Cc4nc(-c5ccccc5)no4)c3)[nH]c2n(CCC)c1=O CHEMBL200779 Ki 1.0 nM
Cn1c(=O)c2nc(-c3cnn(Cc4cccc(C(F)(F)F)c4)c3)[nH]c2n(C)c1=O CHEMBL208824 Ki 1.0 nM
Cn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(Br)cc5)CC4)cc3)cc2n(C)c1=O CHEMBL437309 IC50 1.0 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OC(C)(C)C(=O)N4CCN(c5nc6ccc(Cl)cc6s5)CC4)cc3)cc21 CHEMBL259479 Ki 1.0 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(Br)cc4)cc3)c(O)c2n(CCC)c1=O CHEMBL456125 Ki 1.0 nM
O=C(Nc1ccc(-c2ccncc2)c(-c2ccco2)n1)C1CC1 CHEMBL1081812 Ki 1.0 nM
O=C(Nc1ccc(-c2ccncc2F)c(-c2ccco2)n1)C1CC1 CHEMBL1079804 Ki 1.0 nM
O=c1[nH]c(=O)c2cc(-c3ccncn3)c(-c3ccco3)nc2[nH]1 CHEMBL1080513 Ki 1.0 nM
O=C(COc1ccc2[nH]c(=O)c(-c3nccs3)c(CCc3ccccc3)c2c1)NC1(c2ccccc2)CC1 CHEMBL1290001 Ki 1.0 nM
O=C(Nc1cnc(-c2ccncc2)c(-c2ccccc2F)n1)C1CC1 CHEMBL1672623 Ki 1.0 nM
Cn1c(=O)c2[nH]c(-c3ccc(OC4CCCC4)cc3)nc2n(C)c1=O CHEMBL3121726 Ki 1.0 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC4CC(=O)N(c5ccc(C(F)(F)F)cc5)C4)cc3)nc2n(CCC)c1=O CHEMBL4095766 Ki 1.0 nM
N#Cc1c(N)nc(SCc2ncc[nH]2)c(C#N)c1-c1ccc(O)cc1 CHEMBL122622 Ki 1.0 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cc(F)cc(OC)c5)CC4)cc3)[nH]c2c1=O CHEMBL4467573 Ki 1.02 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(O[C@@H](C)C(=O)N4CCN(c5nc6ccc(Cl)cc6s5)CC4)cc3)cc21 CHEMBL4160732 pKi 1.047 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCCCn4ccnc4)cc3)nc2n(C)c1=O CHEMBL3121727 Ki 1.05 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc6c(c5)OCO6)CC4)cc3)[nH]c2c1=O CHEMBL486893 Ki 1.06 nM
CCCN1C(=O)N=C2N=C(c3ccc(S(=O)(=O)N4CCN(Cc5ccc(Cl)cc5)CC4)cc3)N=C2C1=O CHEMBL4215606 IC50 1.06 nM
[3H]C([3H])([3H])C([3H])([3H])Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C#N)cc4)cc3)nc2n(CC([3H])([3H])C([3H])([3H])[3H])c1=O CHEMBL1628266 Kd 1.13 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccccc5)CC4)cc3)[nH]c2c1=O CHEMBL519813 Ki 1.15 nM
CCOC(=O)C1=C(C)Nc2nc3cc(Br)ccc3n2[C@@H]1c1ccoc1 CHEMBL5401787 Ki 1.17 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(OC)cc5)CC4)cc3)[nH]c2c1=O CHEMBL482648 Ki 1.19 nM
CCCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5OC)CC4)cc3)nc2c1=O CHEMBL37726 Ki 1.2 nM
CCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)NCCO)cc3)nc2c1=O CHEMBL416417 Ki 1.2 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)NCCO)cc3)cc2n(C)c1=O CHEMBL490262 Ki 1.2 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC(O)C4CC(=O)N(c5cccc(C(F)(F)F)c5)C4)c3)nc2n(CCC)c1=O CHEMBL4092455 Ki 1.2 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(OC)c(F)c5)CC4)cc3)[nH]c2c1=O CHEMBL4556744 Ki 1.24 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(F)cc5)CC4)cc3)[nH]c2c1=O CHEMBL520297 Ki 1.27 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(OC)c5)CC4)cc3)[nH]c2c1=O CHEMBL4437222 Ki 1.28 nM
CCCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)N4CCN(Cc5ccccc5)CC4)cc3)nc2c1=O CHEMBL38304 Ki 1.3 nM
CC(C)(NC(=O)COc1ccc2[nH]c(=O)c(-c3nccs3)c(CCc3ccccc3)c2c1)c1ccccc1 CHEMBL1290101 Ki 1.3 nM
CCCn1c(=O)[nH]c2nc(-c3cnn(CC#Cc4ccc(C(F)(F)F)cc4)c3)[nH]c2c1=O CHEMBL4087158 Ki 1.3 nM
C[C@H](Oc1ccc(-c2cc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1)C(=O)Nc1ccc(Br)cc1 CHEMBL4175851 pKi 1.318 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccccc5)CC4)cc3)[nH]c2c1=O CHEMBL212625 Ki 1.33 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCCN4CCOCC4)cc3)nc2n(C)c1=O CHEMBL3121723 Ki 1.34 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C(C)=O)cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL17002 Ki 1.39 nM
CCCn1c(=O)c2c(nc(-c3ccc(OCC(=O)Nc4ccc(C(C)=O)cc4)cc3)n2C)n(CCC)c1=O CHEMBL592891 Ki 1.39 nM
Oc1c(-c2ccccc2)nnc2nc3ccccc3n12 CHEMBL7113 IC50 1.4 nM
CNc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1 CHEMBL1077943 IC50 1.4 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccccc4)cc3)[nH]c2n(CCC)c1=O CHEMBL16677 Ki 1.48 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5cccc(Cl)c5)CC4)cc3)cc2n(CCC)c1=O CHEMBL260051 Ki 1.5 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC(=O)N4CCN(c5cccc(C(F)(F)F)c5)CC4)c3)nc2n(CCC)c1=O CHEMBL4095843 Ki 1.5 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4ccc(C(F)(F)F)cc4)c3)nc2n(CCC)c1=O CHEMBL4088514 Ki 1.5 nM
CCOC(=O)C1=C(C)Nc2nc3cc(Br)ccc3n2C1c1ccoc1 CHEMBL5398999 KB 1.5 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc([N+](=O)[O-])cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL16787 Ki 1.52 nM
CC(Oc1ccc(-c2cc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1)C(=O)Nc1ccc(Br)cc1 CHEMBL370588 pKi 1.549 nM
Nc1nc(-c2ccccc2)c(-c2ccnnc2)c2nc(Cc3ncccc3F)nn12 CHEMBL4862010 IC50 1.55 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(C)cc5)CC4)cc3)[nH]c2c1=O CHEMBL520617 Ki 1.58 nM
CCCn1c(=O)[nH]c2nc(-c3cnn(CC#Cc4ccc(F)cc4)c3)[nH]c2c1=O CHEMBL4079273 Ki 1.6 nM
CCCn1c(=O)[nH]c2nc(-c3cnn(CC#Cc4ccc(OC(F)(F)F)cc4)c3)[nH]c2c1=O CHEMBL4059779 Ki 1.6 nM
COc1cccc2c1nc(N)n1nc([C@H]3C[C@H](c4ncc(C(C)(C)N)cc4C)C3)nc21 CHEMBL5413371 IC50 1.6 nM
CCCn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(c5ccc(Cl)cc5)CC4)cc3)nc2n(C)c1=O CHEMBL4537196 Kb 1.61 nM
CCCn1c(=O)c2[nH]c(-c3cc(OCC(=O)Nc4ccc5c(c4)OCO5)nn3C)nc2n(CCC)c1=O CHEMBL260331 Kd 1.65 nM
[3H]C([3H])([3H])C([3H])([3H])Cn1c(=O)c2[nH]c(-c3cc(OCC(=O)Nc4ccc5c(c4)OCO5)nn3C)nc2n(CC([3H])([3H])C([3H])([3H])[3H])c1=O CHEMBL506685 Kd 1.65 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N(C)CCc4ccccc4)cc3)[nH]c2c1=O CHEMBL4473749 Ki 1.69 nM
CCCn1c(=O)c2[nH]c(-c3ccc(COC(=O)Nc4ccon4)cc3)cc2n(CCC)c1=O CHEMBL466035 Ki 1.7 nM
C[C@H](NC(=O)COc1ccc2[nH]c(=O)c(-c3nccs3)c(CCc3ccccc3)c2c1)c1ccccc1 CHEMBL1290210 Ki 1.7 nM
CC1=C(C(=O)OC(C)C)C(c2ccco2)n2c(nc3cc(Br)ccc32)N1 CHEMBL5409856 KB 1.7 nM
CCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C)cc4)cc3)[nH]c2n(CC)c1=O CHEMBL16866 Ki 1.78 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC(=O)N4CCN(c5ccc(F)c(Cl)c5)CC4)c3)nc2n(CCC)c1=O CHEMBL4080171 Ki 1.8 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4cccc(C(=O)O)c4)c3)nc2n(CCC)c1=O CHEMBL4070936 Ki 1.8 nM
Cc1ccc(N2CCN(C(=O)C(C)Oc3ccc(-c4cc5c([nH]4)c(=O)n(C)c(=O)n5C)cc3)CC2)cc1 CHEMBL260692 Log Ki 1.82 nM
Cc1ccc(N2CCN(C(=O)[C@H](C)Oc3ccc(-c4cc5c([nH]4)c(=O)n(C)c(=O)n5C)cc3)CC2)cc1 CHEMBL4175454 pKi 1.82 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(OCC(=O)NCCC4=C5C(C)=CC(C)=[N+]5[B-](F)(F)n5c(C)cc(C)c54)cc3)[nH]c2c1=O CHEMBL4205635 Ki 1.83 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C)cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL432664 Ki 1.88 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C#N)cc4)cc3)nc2n(CCC)c1=O CHEMBL273807 Ki 1.9 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(Cl)cc5F)CC4)cc3)[nH]c2c1=O CHEMBL4461478 Ki 1.91 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCCN4CCCC4)cc3)nc2n(C)c1=O CHEMBL3121724 Ki 1.97 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(OC)cc5)CC4)cc3)[nH]c2c1=O CHEMBL486481 Ki 1.99 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccc(C(F)(F)F)cc5)CC4)cc3)cc21 CHEMBL412112 Ki 2.0 nM
CCn1c(=O)c2[nH]c(-c3cnn(Cc4ccccc4)c3)nc2n(C)c1=O CHEMBL408266 Ki 2.0 nM
CCCn1c(=O)c2[nH]c(-c3ccc(COC(=O)Nc4ccc(F)cc4)cc3)cc2n(CCC)c1=O CHEMBL512276 Ki 2.0 nM
O=C(Nc1ccc(-c2ccncc2)c(-c2ccccc2F)n1)C1CC1 CHEMBL1082028 Ki 2.0 nM
O=C(Nc1ccc(-c2ccncc2)c(-c2cccc(F)c2)n1)C1CC1 CHEMBL1076587 Ki 2.0 nM
O=C(Nc1cnc(-c2ccncc2F)c(-c2cnco2)n1)C1CC1 CHEMBL1672633 Ki 2.0 nM
Cc1c(C#N)cccc1-c1cc(-c2cn(Cc3cccc(C(C)(C)O)n3)nn2)nc(N)n1 CHEMBL4740383 KB 2.0 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NCc4ccccc4)cc3)[nH]c2n(CCC)c1=O CHEMBL275605 Ki 2.04 nM
CC1=C(C(=O)OC(C)C)[C@@H](c2ccco2)n2c(nc3cc(Cl)ccc32)N1 CHEMBL5394605 Ki 2.04 nM
Cn1c(=O)c2[nH]c(-c3ccc(COC(=O)N4CCc5ccccc5C4)cc3)cc2n(C)c1=O CHEMBL469136 Ki 2.1 nM
O=c1c(-c2ccco2)nnc2n(-c3ccc(Cl)cc3)c3ccccc3n12 CHEMBL2030704 IC50 2.11 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(I)cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL278039 Ki 2.13 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C(F)(F)F)cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL277386 Ki 2.14 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(Br)cc4)cc3)cc2n(CCC)c1=O CHEMBL201145 pKi 2.188 nM
O=C(Nc1cnc(-c2ccncc2)c(-c2ccco2)n1)C1CC1 CHEMBL1672611 Ki 2.2 nM
Cc1ccc(-c2nc(NC(=O)C3CC3)cnc2-c2ccncc2)o1 CHEMBL1672619 Ki 2.2 nM
CCCn1c(=O)[nH]c2nc(-c3cnn(CC#Cc4cccc(C(F)(F)F)c4)c3)[nH]c2c1=O CHEMBL4105001 Ki 2.2 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(F)cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL16929 Ki 2.22 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCc5ccccc5C4)cc3)cc2n(CCC)c1=O CHEMBL258978 Log Ki 2.291 nM
CCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)nc(F)nc32)[C@H](O)[C@@H]1O CHEMBL2042297 EC50 2.3 nM
CCCn1c(=O)[nH]c2cc(-c3ccc(OCC(=O)Nc4ccc(F)cc4)cc3)[nH]c2c1=O CHEMBL1170166 pKi 2.344 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(Br)cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL17003 Ki 2.35 nM
CCCn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)F)cc3)nc2n(CCC)c1=O CHEMBL5172513 pKi 2.399 nM
COCCn1c(=O)n(CCc2ccccc2)c(=O)c2c(C)c(Cc3nc[nH]c3C)sc21 CHEMBL4569909 IC50 2.4 nM
O=c1c(-c2ccccc2)nnc2n(-c3ccc(Cl)cc3)c3ccccc3n12 CHEMBL2030703 IC50 2.42 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(Cl)cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL275427 Ki 2.47 nM
CCCn1c(=O)c2nc(-c3ccc(I)cc3)[nH]c2n(CCC)c1=O CHEMBL36963 Ki 2.5 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCC(c5ccccc5)CC4)cc3)cc21 CHEMBL259857 Ki 2.5 nM
O=c1c(-c2ccccc2)nnc2n(CCc3ccccc3)c3ccccc3n12 CHEMBL2030705 IC50 2.5 nM
CCN(CC)CCOc1ccc(-c2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1 CHEMBL3121721 Ki 2.59 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(Cc5ccccc5)CC4)cc3)c(O)c2n(CCC)c1=O CHEMBL506179 Ki 2.6 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CCC4CC(=O)N(c5cccc(C(F)(F)F)c5)C4)c3)nc2n(CCC)c1=O CHEMBL4100199 Ki 2.6 nM
CC1=C(C(=O)OC(C)C)[C@@H](c2ccoc2)n2c(nc3cc(Cl)ccc32)N1 CHEMBL5393920 Ki 2.6 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(Br)cc4)cc3)cc2n(C)c1=O CHEMBL370378 pKi 2.63 nM
CCCCn1c(=O)[nH]c2[nH]c(-c3ccc(Br)cc3)nc2c1=O CHEMBL34762 Ki 2.7 nM
COc1cccc2c1nc(N)n1nc([C@H]3C[C@H](c4ncc(C(C)(C)N)cc4Cl)C3)nc21 CHEMBL5438060 IC50 2.7 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccccc4C(C)=O)cc3)[nH]c2n(CCC)c1=O CHEMBL17341 Ki 2.74 nM
O=C(Nc1nc(-c2ccccc2)c(-c2ccncc2)s1)c1ccco1 CHEMBL2391834 Ki 2.78 nM
Cn1c(=O)c2[nH]c(-c3ccc(COC(=O)Nc4ccccc4)cc3)cc2n(C)c1=O CHEMBL512290 Ki 2.8 nM
CCCn1c(=O)[nH]c2nc(-c3cnn(CC#Cc4cccc(OC(F)(F)F)c4)c3)[nH]c2c1=O CHEMBL4081707 Ki 2.8 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5cccc(Cl)c5)CC4)cc3)cc2n(C)c1=O CHEMBL260693 Log Ki 2.818 nM
CCCn1c(=O)[nH]c2nc(-c3cccc(N=C=S)c3)[nH]c2c1=O CHEMBL5208506 pKi 2.818 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCC(O)(c5ccc(Cl)cc5)CC4)cc3)cc2n(C)c1=O CHEMBL259360 Log Ki 2.884 nM
CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(Br)cc4)cc3)nc2n(CCCOC)c1=O CHEMBL563425 pKi 2.884 nM
CCCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)N4CCN(C(=O)OCc5ccccc5)CC4)cc3)nc2c1=O CHEMBL416963 Ki 2.9 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCCC4CCNCC4)cc3)nc2n(C)c1=O CHEMBL3121722 Ki 2.9 nM
COc1cccc2c1nc(N)n1nc(C3CC3c3nc4ccccc4n3C)nc21 CHEMBL5430246 IC50 2.9 nM
CC1=C(C(=O)OC(C)C)[C@@H](c2ccco2)n2c(nc3cc(Br)ccc32)N1 CHEMBL5408908 Ki 2.97 nM
Cc1nccn1-c1sc(Nc2cnccn2)nc1-c1cccc(C#N)c1 CHEMBL2113096 KB 3.0 nM
O=c1[nH]c2nc(-c3cnn(Cc4cccc(C(F)(F)F)c4)c3)[nH]c2c(=O)n1CC1CC1 CHEMBL404349 Ki 3.0 nM
O=c1[nH][nH]c2nc(-c3ccco3)c(-c3ccncn3)cc12 CHEMBL1080497 Ki 3.0 nM
O=C(Nc1cnc(-c2ccncc2)c(-c2ccco2)n1)C1CCC1 CHEMBL1672615 Ki 3.0 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC4CC(=O)N(c5ccc(C(F)(F)F)cc5)C4)nc3)nc2n(CCC)c1=O CHEMBL4065717 Ki 3.0 nM
CCCn1c(=O)[nH]c2nc(-c3cnn(CC#Cc4cccc(F)c4)c3)[nH]c2c1=O CHEMBL4097296 Ki 3.0 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(F)cc4)cc3)cc2n(C)c1=O CHEMBL199446 pKi 3.02 nM
CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(F)cc4)cc3)nc2n(CCCOC)c1=O CHEMBL551904 pKi 3.02 nM
CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccccc4)cc3)nc2n(CCCOC)c1=O CHEMBL560624 pKi 3.02 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)NC4CCN(Cc5ccccc5)CC4)cc3)[nH]c2c1=O CHEMBL486282 Ki 3.03 nM
O=c1c(-c2ccccc2)nnc2n(-c3ccccc3)c3ccc(Cl)cc3n12 CHEMBL2030707 IC50 3.1 nM
COc1cccc2c1nc(N)n1nc(C3CC3c3ccc4c(c3)CCNC4)nc21 CHEMBL5413330 IC50 3.1 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(Cl)cc4)cc3)cc2n(CCC)c1=O CHEMBL382764 pKi 3.162 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)NCc4ccccc4)cc3)cc2n(CCC)c1=O CHEMBL201773 pKi 3.162 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(OC)nc4)cc3)cc2n(C)c1=O CHEMBL203037 pKi 3.162 nM
CCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL464859 pEC50 3.162 nM
Cn1c(=O)c2[nH]c(-c3ccc(COC(=O)Nc4ccco4)cc3)cc2n(C)c1=O CHEMBL468506 Ki 3.2 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccccc5F)CC4)cc3)[nH]c2c1=O CHEMBL4466211 Ki 3.22 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OC(C)C(=O)Nc4ccc(F)cc4)cc3)cc2n(CCC)c1=O CHEMBL380847 pKi 3.236 nM
CCCn1c(=O)c2[nH]c(-c3ccc(N=C=S)cc3)nc2n(CCC)c1=O CHEMBL5196082 pKi 3.236 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(OCC(=O)NCCCCc4ccccc4)cc3)[nH]c2c1=O CHEMBL4218460 Ki 3.3 nM
COc1cccc2c1nc(N)n1nc([C@H]3C[C@H](c4ccc(C(C)(C)O)cn4)C3)nc21 CHEMBL5426841 IC50 3.3 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(F)cc4)cc3)cc2n(CCC)c1=O CHEMBL201281 pKi 3.311 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C(=O)NC)cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL17167 Ki 3.34 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccc(Cl)cc5)CC4)cc3)cc2n(C)c1=O CHEMBL261056 Log Ki 3.388 nM
CCOC(=O)C1=C(C)Nc2nc3cc(Cl)ccc3n2[C@@H]1c1cocn1 CHEMBL5426699 Ki 3.39 nM
COc1cc(OCC(=O)Nc2ccc(Br)cc2)ccc1-c1cc2c([nH]1)c(=O)n(C)c(=O)n2C CHEMBL201750 pKi 3.467 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccc(Br)cc5)CC4)cc3)cc2n(C)c1=O CHEMBL411075 Log Ki 3.467 nM
CC1=C(C(=O)OC(C)C)C(c2ccco2)n2c(nc3ccccc32)N1 CHEMBL3787197 Ki 3.49 nM
CCC(=O)Nc1cnc(-c2ccncc2)c(-c2ccco2)n1 CHEMBL1672613 Ki 3.5 nM
CCCn1c(=O)c2[nH]c(-c3cc(OCc4nc5cc(Cl)ccc5[nH]4)no3)nc2n(CCC)c1=O CHEMBL1955915 Ki 3.5 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4ccc(C(=O)OCC)cc4)c3)nc2n(CCC)c1=O CHEMBL4075650 Ki 3.5 nM
CC(=O)c1ccc(NC(=O)COc2ccc(-c3cc4c([nH]3)c(=O)n(C)c(=O)n4C)cc2)cc1 CHEMBL439868 pKi 3.548 nM
CCCn1c(=O)[nH]c2cc(-c3ccc(OCC(=O)Nc4ccc(Br)cc4)cc3)[nH]c2c1=O CHEMBL1170167 pKi 3.548 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(O)c(Cl)c5)CC4)cc3)[nH]c2c1=O CHEMBL4538468 Ki 3.55 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CCN(c5cccc(C(F)(F)F)c5)C4)c3)nc2n(CCC)c1=O CHEMBL4074412 Ki 3.6 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4cccc(OC(F)(F)F)c4)c3)nc2n(CCC)c1=O CHEMBL4076435 Ki 3.6 nM
CCC(=O)Nc1cc(-c2ccc(OC)cc2)nc(-c2ccc(OC)cc2)n1 CHEMBL1650356 Ki 3.6 nM
CCCn1c(=O)[nH]c2[nH]c(-c3ccc(S(=O)(=O)NCCc4ccccc4)cc3)nc2c1=O CHEMBL211521 Ki 3.62 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5nc6cc(Cl)ccc6s5)CC4)cc3)cc2n(C)c1=O CHEMBL440418 Log Ki 3.631 nM
CCCn1c(=O)c2nc(-c3ccc(/C=C/C(=O)Nc4ccccc4C(C)=O)cc3)[nH]c2n(CCC)c1=O CHEMBL17202 Ki 3.65 nM
CCOC(=O)C1=C(C)Nc2nc3ccccc3n2[C@@H]1c1cocn1 CHEMBL4644677 Ki 3.66 nM
CCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)OC)cc3)nc2c1=O CHEMBL284288 Ki 3.7 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4cccc(C#N)c4)c3)nc2n(CCC)c1=O CHEMBL4104876 Ki 3.7 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(O)cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL444281 Ki 3.71 nM
CCCn1c(=O)c2nc(-c3ccc(Br)cc3)[nH]c2n(CCC)c1=O CHEMBL40055 Ki 3.8 nM
O=c1[nH]c(=O)c2nc3ccccc3nc2[nH]1 CHEMBL68500 Ki 3.8 nM
CCCn1c(=O)c2[nH]c(C3CCCC3)nc2n(CCC)c1=O CHEMBL183 IC50 3.8 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C#N)cc4)cc3)cc2n(C)c1=O CHEMBL382135 pKi 3.802 nM
CC(Oc1ccc(-c2cc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1)C(=O)Nc1ccc(F)cc1 CHEMBL199486 pKi 3.89 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C(=O)OC)cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL16741 Ki 3.93 nM
Cn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(Cl)s5)CC4)cc3)cc2n(C)c1=O CHEMBL211813 IC50 4.0 nM
O=C(Nc1ccc(-c2ccncn2)c(-c2ccco2)n1)C1CC1 CHEMBL1081971 Ki 4.0 nM
O=C(Nc1ccc(-c2ccncc2)c(-c2ccc(F)cc2)n1)C1CC1 CHEMBL1081038 Ki 4.0 nM
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(CN(C)S(C)(=O)=O)cc3)sc12 CHEMBL1172277 Ki 4.0 nM
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(C(=O)N4CCCCC4)cc3)sc12 CHEMBL1170135 Ki 4.0 nM
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3cnn(Cc4cccc(C(F)(F)F)c4)c3)sc12 CHEMBL1171164 Ki 4.0 nM
CCCn1c(=O)c2[nH]c(-c3cc(=O)[nH]n3C)nc2n(CCC)c1=O CHEMBL1955922 Ki 4.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5ccc(OC(F)(F)F)cc5)C4)c3)nc2n(CCC)c1=O CHEMBL4091110 Ki 4.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5ccc(C(F)(F)F)cc5)C4)c3)nc2n(CC)c1=O CHEMBL4074253 Ki 4.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(C(C)C4CC(=O)N(c5cccc(C(F)(F)F)c5)C4)c3)nc2n(CCC)c1=O CHEMBL4073346 Ki 4.0 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC4CC(=O)N(c5ccc(F)cc5)C4)nc3)nc2n(CCC)c1=O CHEMBL4088043 Ki 4.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5ccc(F)cc5)C4)c3)nc2n(CC)c1=O CHEMBL4065629 Ki 4.0 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OC(C)C(=O)NCc4ccc(Cl)cc4)cc3)cc2n(CCC)c1=O CHEMBL201028 pKi 4.074 nM
CCCn1c(=O)c2[nH]c(-c3cc(OCc4nc5cc(Br)ccc5[nH]4)no3)nc2n(CCC)c1=O CHEMBL1955916 Ki 4.1 nM
Nc1nc(-c2ccccc2)c(-c2ccc(=O)[nH]c2)c2nc(Cc3ncc(F)cc3Cl)nn12 CHEMBL4864129 IC50 4.13 nM
C=CCCCCCCCCCCOCCOCCOCCOCCOc1ccc(-c2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1 CHEMBL589251 Ki 4.16 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccc(C(F)(F)F)cc5)CC4)cc3)cc2n(C)c1=O CHEMBL412063 Log Ki 4.169 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccc(C(F)(F)F)cc5)CC4)cc3)cc2n(CCC)c1=O CHEMBL260221 Log Ki 4.169 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OC(C)(C)C(=O)N4CCN(c5ccccc5)CC4)cc3)cc21 CHEMBL428604 Log Ki 4.169 nM
CCCn1c(=O)[nH]c2[nH]c(-c3ccc(S(=O)(=O)NCc4ccccc4)cc3)nc2c1=O CHEMBL209230 Ki 4.2 nM
Nc1nc(NCCc2cccnc2)nc2sc(-c3ccco3)nc12 CHEMBL4162638 IC50 4.21 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5c(Cl)cncc5Cl)CC4)cc3)cc21 CHEMBL258948 Log Ki 4.266 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(O)cc5)CC4)cc3)[nH]c2c1=O CHEMBL4582353 Ki 4.3 nM
CCCn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(c5ccc(Cl)cc5)CC4)cc3)nc2n(CC)c1=O CHEMBL4547661 Ki 4.31 nM
CCCn1c(=O)[nH]c2[nH]c(-c3ccc(Br)cc3)nc2c1=O CHEMBL35701 Ki 4.4 nM
Cn1c(=O)c2nc(-c3ccc(S(=O)(=O)NCCc4ccccc4)cc3)[nH]c2n(C)c1=O CHEMBL210585 Ki 4.48 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5cccc(C(F)(F)F)c5)C4)c3)nc2n(CC)c1=O CHEMBL4094755 Ki 4.5 nM
Nc1sc(-c2ccc(C(=O)NCCCCCCNc3ncnc4c3ncn4[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)cc2)c(-c2cccc(C(F)(F)F)c2)c1C(=O)c1ccccc1 CHEMBL4104819 pEC50 4.571 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC4CC(=O)N(c5cccc(F)c5)C4)nc3)nc2n(CCC)c1=O CHEMBL4059759 Ki 4.6 nM
O=C(COc1ccc(-c2cc3c([nH]2)c(=O)n(CC2CC2)c(=O)n3CC2CC2)cc1)Nc1ccccc1 CHEMBL199862 pKi 4.677 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OC(C)C(=O)N4CCc5ccccc5C4)cc3)cc2n(CCC)c1=O CHEMBL412293 Log Ki 4.677 nM
CCCn1c(=O)[nH]c2[nH]c(-c3ccccc3)nc2c1=O CHEMBL274855 Ki 4.7 nM
CC1=C(C(=O)OC(C)C)C(c2ccco2)NC(=S)N1 CHEMBL3091713 KB 4.7 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OC(CC)C(=O)Nc4ccc(F)cc4)cc3)cc2n(CCC)c1=O CHEMBL381091 pKi 4.786 nM
CC(Oc1ccc(-c2cc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1)C(=O)Nc1ccccc1 CHEMBL199611 pKi 4.786 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5)CC4)cc3)cc2n(CCC)c1=O CHEMBL259057 Log Ki 4.786 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(F)cc4)nc3)[nH]c2n(CCC)c1=O CHEMBL199249 Ki 4.8 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)NCc4ccc(Cl)cc4)cc3)cc2n(C)c1=O CHEMBL203305 pKi 4.898 nM
COCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5)CC4)cc3)cc2n(CCOC)c1=O CHEMBL261212 Log Ki 4.898 nM
CCCn1c(=O)c2nc(-c3ccc(O)nc3)[nH]c2n(CCC)c1=O CHEMBL199196 Ki 4.9 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4cccc(C(F)(F)F)c4)c3)nc2n(CCC)c1=O CHEMBL4078183 Ki 4.9 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4cccc(C(C)=O)c4)cc3)[nH]c2n(CCC)c1=O CHEMBL16534 Ki 4.92 nM
CN(C)CCOc1ccc(-c2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1 CHEMBL3121720 Ki 4.95 nM
Nc1nc2nn(CCc3ccccc3)cc2c2nc(-c3ccco3)nn12 CHEMBL16867 Ki 5.0 nM
CCn1c(=O)c2nc(-c3cnn(Cc4cccc(F)c4)c3)[nH]c2n(CC)c1=O CHEMBL426504 Ki 5.0 nM
O=c1[nH]c2nc(-c3cnn(Cc4cccc(F)c4)c3)[nH]c2c(=O)n1CC1CC1 CHEMBL253252 Ki 5.0 nM
O=C(Nc1ccc(-c2ccncc2Cl)c(-c2ccco2)n1)C1CC1 CHEMBL1079803 Ki 5.0 nM
Cc1ccc(-c2nc(NC(=O)C3CC3)ccc2-c2ccncc2)o1 CHEMBL1082005 Ki 5.0 nM
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)N3CCC(O)(c4cccc(C(F)(F)F)c4)CC3)sc12 CHEMBL1760899 Ki 5.0 nM
CCCn1c(=O)c2[nH]c(-c3cc(OCc4nc5cc(Cl)ccc5[nH]4)nn3C)nc2n(CCC)c1=O CHEMBL1955899 Ki 5.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC(=O)N4CCN(c5ccc(C)cc5)CC4)c3)nc2n(CCC)c1=O CHEMBL4064755 Ki 5.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4cccc(C)c4)c3)nc2n(CCC)c1=O CHEMBL4077090 Ki 5.0 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OC(C)C(=O)Nc4ccc(OC)cc4)cc3)cc2n(CCC)c1=O CHEMBL202767 pKi 5.129 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OC(C)C(=O)Nc4ccccc4)cc3)cc2n(CCC)c1=O CHEMBL202766 pKi 5.129 nM
Nc1nc(NCCc2ccc(S(N)(=O)=O)cc2)nc2sc(-c3ccco3)nc12 CHEMBL4632532 IC50 5.2 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(-c5ccccc5)cc4)cc3)cc2n(C)c1=O CHEMBL372148 pKi 5.248 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5)CC4)cc3)cc2n(C)c1=O CHEMBL262332 Log Ki 5.248 nM
CCCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C(=O)OC)cc4)cc3)nc2c1=O CHEMBL38193 Ki 5.3 nM
CCCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(CC(=O)O)cc4)cc3)nc2c1=O CHEMBL2112962 Ki 5.3 nM
O=c1c(-c2ccco2)nnc2n(CCc3ccccc3)c3ccccc3n12 CHEMBL2030706 IC50 5.34 nM
CCCn1c(=O)[nH]c2[nH]c(-c3ccc(S(=O)(=O)Oc4ccc([N+](=O)[O-])cc4)cc3)nc2c1=O CHEMBL8732 Ki 5.4 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC4CC(=O)N(c5ccc(F)cc5)C4)cc3)nc2n(CCC)c1=O CHEMBL4069458 Ki 5.4 nM
COc1nc(-c2ncco2)nc(N)c1C(=O)NCc1c(Cl)cccc1Cl CHEMBL4747929 Ki 5.4 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)N(C)c4ccccc4)cc3)[nH]c2n(CCC)c1=O CHEMBL275606 Ki 5.42 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCCCC4)cc3)[nH]c2c1=O CHEMBL488542 Ki 5.43 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(OS(=O)(=O)F)cc3)[nH]c2c1=O CHEMBL5205220 pKi 5.495 nM
CCCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)N4CCN(CC)CC4)cc3)nc2c1=O CHEMBL37875 Ki 5.5 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCC(c5ccccc5)(c5ccccc5)CC4)cc3)cc21 CHEMBL294223 Ki 5.5 nM
CCCn1c(=O)c2[nH]c(-c3cc(OCc4nc5cc(Cl)c(F)cc5[nH]4)no3)nc2n(CCC)c1=O CHEMBL1955919 Ki 5.5 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4ccc(OC(F)(F)F)cc4)c3)nc2n(CCC)c1=O CHEMBL4080646 Ki 5.5 nM
CCCn1c(=O)[nH]c2nc(-c3cnn(Cc4noc(-c5ccc(Cl)cc5)n4)c3)[nH]c2c1=O CHEMBL252048 Ki 5.5 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(F)cc4)cc3)cc2n(C)c1=O CHEMBL201127 pKi 5.623 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(C(=O)c5ccccc5)CC4)cc3)[nH]c2c1=O CHEMBL4543948 Ki 5.69 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5nc6ccc(Cl)cc6s5)CC4)cc3)cc21 CHEMBL407202 Log Ki 5.754 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(I)cc4)cc3)cc2n(C)c1=O CHEMBL200052 pKi 5.888 nM
CCCn1c(=O)c2[nH]c(-c3ccc(COC(=O)Nc4cc[nH]n4)cc3)cc2n(CCC)c1=O CHEMBL466453 Ki 5.9 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4ccc(F)cc4)c3)nc2n(CCC)c1=O CHEMBL4086077 Ki 5.9 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(OCC(=O)NCCCCCC4=C5C(C)=CC(C)=[N+]5[B-](F)(F)n5c(C)cc(C)c54)cc3)[nH]c2c1=O CHEMBL4218673 Ki 5.9 nM
CCCCc1nc2[nH]cnc2c2nc(-c3ccc(C(F)(F)F)cc3)nn12 CHEMBL123705 Ki 6.0 nM
CCCn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(C#N)cc5)CC4)cc3)cc2n(C)c1=O CHEMBL212416 IC50 6.0 nM
Cn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(c5ccccc5)CC4)cc3)cc2n(C)c1=O CHEMBL209742 IC50 6.0 nM
CCn1c(=O)[nH]c2nc(-c3cnn(Cc4cccc(C(F)(F)F)c4)c3)[nH]c2c1=O CHEMBL251876 Ki 6.0 nM
O=c1[nH]c2nc(-c3cnn(Cc4ccccc4)c3)[nH]c2c(=O)n1CC1CC1 CHEMBL252069 Ki 6.0 nM
CCn1c(=O)c2[nH]c(-c3cnn(Cc4cccc(C(F)(F)F)c4)c3)nc2n(C)c1=O CHEMBL259342 Ki 6.0 nM
CCn1c(=O)c2[nH]c(-c3cnn(Cc4cccc(F)c4)c3)nc2n(C)c1=O CHEMBL260490 Ki 6.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(Cc4cccc(C(F)(F)F)c4)c3)nc2n(CC)c1=O CHEMBL260933 Kb 6.0 nM
Cc1ccc(-c2nc(N)nc3c2nnn3Cc2ccccc2F)o1 CHEMBL461857 Ki 6.0 nM
O=c1[nH]c2cc(-c3ccncn3)c(-c3ccco3)nc2[nH]1 CHEMBL1076563 Ki 6.0 nM
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3cnn(Cc4cccc(F)c4)c3)sc12 CHEMBL1171165 Ki 6.0 nM
CC(=O)Nc1cnc(-c2ccncc2)c(-c2ccco2)n1 CHEMBL1672612 Ki 6.0 nM
O=C(Nc1cnc(-c2ccncc2F)c(-c2ncco2)n1)C1CC1 CHEMBL1672632 Ki 6.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CCN(c5cccc(C(F)(F)F)c5)C4=O)c3)nc2n(CCC)c1=O CHEMBL4103446 Ki 6.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CCN(c5ccc(OC(F)(F)F)cc5)C4=O)c3)nc2n(CCC)c1=O CHEMBL4098127 Ki 6.0 nM
CCCn1c(=O)[nH]c2nc(-c3cnn(Cc4cccc(C(F)(F)F)c4)c3)[nH]c2c1=O CHEMBL404168 Ki 6.0 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OC(CC)C(=O)Nc4ccc(Br)cc4)cc3)cc2n(CCC)c1=O CHEMBL201493 pKi 6.026 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5cccc(Cl)c5)CC4)cc3)cc21 CHEMBL409443 Log Ki 6.026 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccc(OCCO)cc5)CC4)cc3)[nH]c2c1=O CHEMBL4445941 Ki 6.08 nM
CCCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)N4CCN(C(=O)OCC)CC4)cc3)nc2c1=O CHEMBL37933 Ki 6.1 nM
CC1=C(C(=O)OC(C)C)C(c2ccoc2)n2c(nc3cc(Cl)ccc32)N1 CHEMBL5405570 Ki 6.1 nM
CC1=C(C(=O)OC(C)C)C(c2cocn2)n2c(nc3cc(F)ccc32)N1 CHEMBL5409637 Ki 6.1 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(Cc5ccccc5)CC4)cc3)cc2n(CCC)c1=O CHEMBL409514 Log Ki 6.166 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCC(c5ccccc5OC)CC4)cc3)cc21 CHEMBL259151 Log Ki 6.166 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4cccc(OC)c4)c3)nc2n(CCC)c1=O CHEMBL4103585 Ki 6.3 nM
CC1=C(C(=O)OC(C)C)[C@@H](c2ccco2)NC(=S)N1 CHEMBL4797393 Ki 6.3 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccc(C#N)cc5)CC4)cc3)cc2n(C)c1=O CHEMBL410297 Log Ki 6.31 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5Cl)CC4)cc3)cc2n(C)c1=O CHEMBL262333 Log Ki 6.31 nM
Nc1sc(-c2ccc(C(=O)NCCCc3ccc(Nc4ncnc5c4ncn5[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)cc3)cc2)c(-c2cccc(C(F)(F)F)c2)c1C(=O)c1ccccc1 CHEMBL5203917 pEC50 6.31 nM
CC1=C(C(=O)OC(C)C)C(c2cocn2)n2c(nc3cc(Cl)ccc32)N1 CHEMBL5396910 Ki 6.4 nM
CCCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)N4CCN(C(C)=O)CC4)cc3)nc2c1=O CHEMBL37050 Ki 6.5 nM
CCCn1c(=O)c2[nH]c(-c3ccc(S(C)(=O)=O)cc3)c(O)c2n(CCC)c1=O CHEMBL507754 Ki 6.5 nM
CN(C)c1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1 CHEMBL1081160 IC50 6.5 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5cccc(C(F)(F)F)c5)C4)c3)nc2n(CCC)c1=O CHEMBL4099762 Ki 6.5 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4ccc(C)cc4)c3)nc2n(CCC)c1=O CHEMBL4066128 Ki 6.5 nM
CCOC(=O)C1=C(C)Nc2nc3cc(F)ccc3n2C1c1ccco1 CHEMBL5406016 Ki 6.6 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OC(C)C(=O)N4CCN(c5ccccc5)CC4)cc3)cc2n(CCC)c1=O CHEMBL259871 Log Ki 6.607 nM
CCNc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1 CHEMBL1080421 IC50 6.7 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4cccc(F)c4)c3)nc2n(CCC)c1=O CHEMBL4103997 Ki 6.7 nM
CCCCn1c(=O)c2nc(C34CCC(C(=O)NCCCCCCCCN=[N+]=[N-])(CC3)CC4)[nH]c2n(CCCNC(=O)c2ccc(S(=O)(=O)F)cc2)c1=O CHEMBL5076192 Ki 6.7 nM
C#CCn1c(=O)[nH]c2[nH]c(-c3ccc(Br)cc3)nc2c1=O CHEMBL286527 Ki 6.8 nM
CC1=C(C(=O)O[C@H](C)C(F)(F)F)[C@@H](c2ccco2)n2c(nc3ccccc32)N1 CHEMBL4465889 Ki 6.91 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc([N+](=O)[O-])cc4)cc3)cc2n(C)c1=O CHEMBL381214 pKi 6.918 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(OC(F)(F)F)cc4)cc3)cc2n(CCC)c1=O CHEMBL201239 pKi 6.918 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5Cl)CC4)cc3)cc2n(CCC)c1=O CHEMBL259870 Log Ki 6.918 nM
Cn1cc(-c2c(-c3ccccc3)nc(N)n3nc(Cc4ncccc4F)nc23)ccc1=O CHEMBL4870159 IC50 6.97 nM
N#Cc1cccc(-c2nc(Nc3cnccn3)sc2-n2ccnc2)c1 CHEMBL2113095 KB 7.0 nM
Cn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(F)cc5F)CC4)cc3)cc2n(C)c1=O CHEMBL210088 IC50 7.0 nM
Cn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(F)c5)CC4)cc3)cc2n(C)c1=O CHEMBL210383 IC50 7.0 nM
CCCn1c(=O)c2[nH]c(-c3cc(C)n(CC(=O)Nc4ccc(Cl)cc4)n3)nc2n(CCC)c1=O CHEMBL258571 Ki 7.0 nM
Cn1c(=O)n(CC2CC2)c(=O)c2[nH]c(-c3cnn(Cc4cccc(F)c4)c3)nc21 CHEMBL259300 Ki 7.0 nM
CC(=O)Nc1ccc(-c2ccncc2)c(-c2ccco2)n1 CHEMBL1081811 Ki 7.0 nM
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3cc[nH]c3)sc12 CHEMBL1170519 IC50 7.0 nM
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(C(=O)N4CCOCC4)cc3)sc12 CHEMBL1170134 Ki 7.0 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(OCC(=O)NCc4ccccc4)cc3)[nH]c2c1=O CHEMBL4213768 Ki 7.0 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccc(OCCOCCOC)cc5)CC4)cc3)[nH]c2c1=O CHEMBL4575279 Ki 7.02 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5c(Cl)cncc5Cl)CC4)cc3)cc2n(C)c1=O CHEMBL258568 Log Ki 7.079 nM
CCCn1c(=O)c2[nH]c(-c3ccc(COC(=O)Nc4ccccc4)cc3)cc2n(CCC)c1=O CHEMBL466021 Ki 7.1 nM
Nc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1 CHEMBL1080241 IC50 7.1 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(c5ccccc5)C(C)C4)cc3)[nH]c2c1=O CHEMBL4586090 Ki 7.15 nM
CCOC(=O)C1=C(C)Nc2nc3cc(Cl)ccc3n2C1c1ccoc1 CHEMBL5433210 Ki 7.21 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCc5ccccc5C4)cc3)cc21 CHEMBL408185 Log Ki 7.244 nM
CCNC(=O)[C@H]1O[C@@H](n2cnc3c(Nc4ccc(OCC(=O)Nc5ccccc5)cc4)ncnc32)[C@H](O)[C@@H]1O CHEMBL226193 EC50 7.3 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4ccc(F)cc4)c3)nc2n(CC)c1=O CHEMBL4096746 Ki 7.3 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4cccc(F)c4)c3)nc2n(CC)c1=O CHEMBL4059836 Ki 7.4 nM
CCCn1c(=O)n(CC(C)C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5)CC4)cc3)cc21 CHEMBL259874 Log Ki 7.413 nM
CCn1c(=O)c2c(nc(Cc3cccs3)n2C)n(Cc2ccco2)c1=O CHEMBL606753 pKi 7.413 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(OCC(=O)NCCc4ccccc4)cc3)[nH]c2c1=O CHEMBL4204683 Ki 7.45 nM
CCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(CCc5ccccc5)CC4)cc3)[nH]c2c1=O CHEMBL519556 Ki 7.49 nM
CCCn1c(=O)c2[nH]c(-c3cc(=O)[nH]n3C)cc2n(CCC)c1=O CHEMBL1955923 Ki 7.5 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC4CC(=O)N(c5cccc(C(F)(F)F)c5)C4)cc3)nc2n(CCC)c1=O CHEMBL4068421 Ki 7.5 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(CCc5ccccc5)CC4)cc3)[nH]c2c1=O CHEMBL488541 Ki 7.51 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5c(Cl)cncc5Cl)CC4)cc3)cc2n(CCC)c1=O CHEMBL258979 Log Ki 7.586 nM
CC1=C(C(=O)OC(C)C)C(c2cocn2)n2c(nc3ccc(F)cc32)N1 CHEMBL5427742 Ki 7.6 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C(N)=O)cc4)cc3)[nH]c2n(CCC)c1=O CHEMBL275360 Ki 7.75 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)NCCN)cc3)nc2n(CCC)c1=O CHEMBL273094 Ki 7.75 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(CS(=O)(=O)N5CCCC5)cc4)cc3)cc2n(CCC)c1=O CHEMBL201008 pKi 7.762 nM
CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccccc4)cc3)cc2n(CC)c1=O CHEMBL203413 pKi 7.762 nM
CCCn1c(=O)c2[nH]c(-c3ccc(N(C=O)CC(=O)Nc4ccc(Br)cc4)cc3)cc2n(CCC)c1=O CHEMBL201293 pKi 7.762 nM
CCCn1c(=O)c2[nH]c(C34CCC(C(=O)NCCNC(=O)CCNC(=O)CCNC(=O)CCCCCNC(=O)COc5ccc(/C=C/C6=[N+]7C(=Cc8ccc(-c9cccs9)n8[B-]7(F)F)C=C6)cc5)(CC3)CC4)nc2n(CCC)c1=O CHEMBL5075285 pKd 7.762 nM
CCCn1c(=O)c2[nH]c(-c3ccc(COC(=O)Nc4cnccn4)cc3)cc2n(CCC)c1=O CHEMBL467271 Ki 7.8 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4ccccc4C(=O)OCC)c3)nc2n(CCC)c1=O CHEMBL4069730 Ki 7.8 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(OCC(=O)NCCCCCCCCCCC4=C5C(C)=CC(C)=[N+]5[B-](F)(F)n5c(C)cc(C)c54)cc3)[nH]c2c1=O CHEMBL4217459 Ki 7.82 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OC(C)(C)C(=O)Nc4ccccc4)cc3)cc2n(CCC)c1=O CHEMBL201157 pKi 7.943 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C(C)(C)C)cc4)cc3)cc2n(CCC)c1=O CHEMBL201749 pKi 7.943 nM
Nc1n[nH]c2nc(-c3ccco3)c(-c3ccncn3)cc12 CHEMBL1082001 Ki 8.0 nM
COC(=O)CN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(F)cc3)sc12 CHEMBL1171525 IC50 8.0 nM
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(-n4ccnc4)cc3)sc12 CHEMBL1172275 Ki 8.0 nM
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccnn3C)sc12 CHEMBL1170367 Ki 8.0 nM
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)[C@@H]3CC[C@H](NC(=O)c4cccc(C(F)(F)F)c4)C3)sc12 CHEMBL1760888 IC50 8.0 nM
CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)[C@@H]3CC[C@@H](NC(=O)c4cccc(C(F)(F)F)c4)C3)sc12 CHEMBL1760889 IC50 8.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5ccc(C)cc5)C4)c3)nc2n(CCC)c1=O CHEMBL4101208 Ki 8.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4cccc(OC(F)(F)F)c4)c3)nc2n(CC)c1=O CHEMBL4067401 Ki 8.0 nM
CCCn1c(=O)c2[nH]c(-c3cc(OCc4nc5cc(C(F)(F)F)ccc5[nH]4)nn3C)nc2n(CCC)c1=O CHEMBL1955902 Ki 8.1 nM
CCOC(=O)C1=C(C)Nc2nc3ccccc3n2C1c1cocn1 CHEMBL4637285 Ki 8.1 nM
CC(Oc1ccc(-c2cc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1)C(=O)N1CCN(c2ccc(Br)cc2)CC1 CHEMBL261068 Log Ki 8.128 nM
CC1=C(C(=O)OC(C)C)C(c2ccoc2)n2c(nc3cc(Br)ccc32)N1 CHEMBL5416209 Ki 8.2 nM
CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(C(C)c5ccccc5)CC4)cc3)[nH]c2c1=O CHEMBL4583860 Ki 8.34 nM
CCOC(=O)C1=C(C)Nc2nc3cc(Cl)ccc3n2C1c1ccco1 CHEMBL5393951 Ki 8.42 nM
CC1=C(C(=O)OC(C)C)C(c2ccoc2)n2c(nc3cc(F)ccc32)N1 CHEMBL5396355 Ki 8.6 nM
CCOC(=O)C1=C(C)Nc2nc3cc(Cl)ccc3n2C1c1cocn1 CHEMBL5411587 Ki 8.6 nM
Cn1cc(-c2c(-c3ccccc3)nc(N)n3nc([C@H](O)c4ncccc4F)nc23)ccc1=O CHEMBL4873266 IC50 8.69 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC4CC(=O)N(c5cccc(C(F)(F)F)c5)C4)nc3)nc2n(CCC)c1=O CHEMBL4087139 Ki 8.7 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCc5ccccc5C4)cc3)cc2n(C)c1=O CHEMBL259105 Log Ki 8.71 nM
CC1=C(C(=O)O[C@@H](C)C(F)(F)F)[C@@H](c2ccco2)n2c(nc3ccccc32)N1 CHEMBL4440908 Ki 8.73 nM
COCCn1c(=O)n(CCc2ccccc2)c(=O)c2c(C)c(Cc3c[nH]c(C)n3)sc21 CHEMBL4576817 IC50 8.8 nM
CCCn1c(=O)c2[nH]c(-c3ccc(N)cc3)cc2n(CCC)c1=O CHEMBL455986 Ki 8.9 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(OCc5ccccc5)cc4)cc3)cc2n(CCC)c1=O CHEMBL377485 pKi 8.913 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OC(C)(C)C(=O)Nc4ccc(F)cc4)cc3)cc2n(CCC)c1=O CHEMBL201128 pKi 8.913 nM
Nc1nc(NCc2ccsc2)nc2sc(-c3ccco3)nc12 CHEMBL4159215 IC50 8.96 nM
CCCn1c(=O)c2nc(-c3ccc(N)cc3)[nH]c2n(CCC)c1=O CHEMBL32598 Ki 9.0 nM
COc1ccc(-c2c(C#N)c(N)nc(SCc3ncc[nH]3)c2C#N)cc1 CHEMBL122396 EC50 9.0 nM
CCCn1c(=O)c2nc(-c3cn[nH]c3)[nH]c2n(CCC)c1=O CHEMBL380176 Ki 9.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5ccc(OC)cc5)C4)c3)nc2n(CCC)c1=O CHEMBL4064289 Ki 9.0 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5cccc(OC(F)(F)F)c5)C4)c3)nc2n(CCC)c1=O CHEMBL4061490 Ki 9.0 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC4CC(=O)N(c5cccc(F)c5)C4)cc3)nc2n(CCC)c1=O CHEMBL4090483 Ki 9.0 nM
Nc1nc(-c2ccc(F)cc2)c(-c2ccc(=O)[nH]c2)c2nc(Cc3ccc(F)cn3)nn12 CHEMBL4858144 IC50 9.03 nM
CC(C)CCn1cc2c(nc(N)n3nc(-c4ccco4)nc23)n1 CHEMBL315150 Ki 9.1 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCC(c5ccc(OC)cc5)CC4)cc3)cc21 CHEMBL429512 Log Ki 9.12 nM
CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C#N)cc4)cc3)nc2n(CCCOC)c1=O CHEMBL557694 pKi 9.12 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccccc4)cc3)cc2n(CCC)c1=O CHEMBL202665 pKi 9.333 nM
CCCn1c(=O)c2[nH]c(-c3cc(OCc4nc5c(Cl)cc(C(F)(F)F)cc5[nH]4)nn3C)nc2n(CCC)c1=O CHEMBL1955907 Ki 9.4 nM
Cn1c(=O)c2[nH]c(-c3ccc(COC(=O)Nc4ccc(F)cc4)cc3)cc2n(C)c1=O CHEMBL469119 Ki 9.5 nM
N#Cc1c(N)nc(SCc2ncc[nH]2)c(C#N)c1-c1ccc(OCC2CC2)cc1 CHEMBL4216880 EC50 9.5 nM
CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(F)cc4)cc3)cc21 CHEMBL381538 pKi 9.55 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccc(F)cc5)CC4)cc3)cc2n(C)c1=O CHEMBL259733 Log Ki 9.55 nM
Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCC(c5ccccc5)(c5ccccc5)CC4)cc3)cc2n(C)c1=O CHEMBL259931 Log Ki 9.55 nM
O=C(COc1ccc(-c2cc3c([nH]2)c(=O)n(CC2CC2)c(=O)n3CC2CC2)cc1)N1CCc2ccccc2C1 CHEMBL259104 Log Ki 9.55 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5ccc(F)cc5)C4)c3)nc2n(CCC)c1=O CHEMBL4072877 Ki 9.7 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)ON4C(=O)CCC4=O)cc3)[nH]c2n(CCC)c1=O CHEMBL27081 Ki 9.75 nM
CCCn1c(=O)c2[nH]c(-c3ccc(OC(CC)C(=O)Nc4ccccc4)cc3)cc2n(CCC)c1=O CHEMBL198338 pKi 9.772 nM
Nc1nc2ccc(Cl)cc2c2nc(-c3ccco3)nn12 CHEMBL16687 Ki 9.8 nM
CCCn1c(=O)c2nc(-c3ccc(OCC(=O)N(Cc4ccccc4)Cc4ccccc4)cc3)[nH]c2n(CCC)c1=O CHEMBL275149 Ki 9.88 nM
CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4ccc(OC(F)(F)F)cc4)c3)nc2n(CC)c1=O CHEMBL4094840 Ki 9.9 nM