COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3[N+](=O)[O-])CC2)C1c1ccc(F)c(F)c1 CHEMBL145843 Ki 0.01 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3[N+](=O)[O-])C[C@@H]2C)C1c1ccc(F)c(F)c1 CHEMBL145547 Ki 0.02 nM
CC(C)Oc1ccccc1N1CCN(Cc2cccc(C(=O)N3CCCCC3)c2)CC1 CHEMBL10085 Ki 0.02 nM
CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(S(N)(=O)=O)c1 CHEMBL836 Ki 0.029 nM
C[C@H](Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)NCCOc1ccccc1OCC(F)(F)F CHEMBL24778 Ki 0.036 nM
Cc1[nH]c(=O)n(CCCN2CCN(c3ccccc3OCC(F)(F)F)CC2)c(=O)c1C CHEMBL292189 Log Ki 0.03981 nM
COc1cc2c(cc1OC)CN(c1cc(N)c3cc(OC)c(OC)cc3n1)CC2 CHEMBL324090 Ki 0.04 nM
COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC CHEMBL2 Ki 0.04 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3[N+](=O)[O-])C[C@H]2C)C1c1ccc(F)c(F)c1 CHEMBL341849 Ki 0.05 nM
COc1cccc(OC)c1OCCN[C@H]1C[C@@H](c2ccccc2)c2ccccc2O1 CHEMBL2234441 Ki 0.05 nM
COc1cccc(OC)c1OCCNC[C@@H]1C[C@H](c2ccccc2)c2ccccc2O1 CHEMBL42472 Log Ki 0.05012 nM
CSc1ccc2c(c1)C(=O)N(CCCCN1CCC(n3c(=O)oc4ccccc43)CC1)S2(=O)=O CHEMBL309518 Ki 0.057 nM
COCC1=C(C(=O)OC)C(c2ccc(F)c(F)c2)N(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3)CC2)C(=O)N1 CHEMBL144933 Ki 0.06 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(c3ccc(C)cc3)(c3ccccc3C)CC2)C1c1ccc(F)c(F)c1 CHEMBL145894 Ki 0.06 nM
O=c1[nH]c2ccccc2c(=O)n1CCCN1CCN(c2ccccc2OCC(F)(F)F)CC1 CHEMBL56863 Log Ki 0.0631 nM
COc1ccc2c(c1)C(=O)N(CCCCN1CCC(n3c(=O)oc4ccccc43)CC1)S2(=O)=O CHEMBL83340 Ki 0.064 nM
CN1C=C(C(=O)NCCCN2CCC(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)NC1=O CHEMBL90086 Ki 0.068 nM
N#Cc1cc(F)ccc1C1CCN(CCCNC(=O)C2=CNC(=O)N[C@@H]2c2ccc(F)c(F)c2)CC1 CHEMBL94188 Ki 0.07 nM
O=C1c2cc(Cl)ccc2S(=O)(=O)N1CCCCN1CCC(n2c(=O)oc3ccccc32)CC1 CHEMBL313990 Ki 0.077 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3C#N)CC2)C1c1ccc(F)c(F)c1 CHEMBL145190 Ki 0.08 nM
COc1cccc(OC)c1OCCN[C@H]1C[C@@H](c2ccccc2)c2ccccc2S1 CHEMBL2234443 Ki 0.08 nM
O=C1c2ccccc2S(=O)(=O)N1CCCCN1CCC(n2c(=O)oc3cc(F)ccc32)CC1 CHEMBL83272 Ki 0.084 nM
COc1cccc(OC)c1OCCNCC1CC(c2ccccc2)c2ccccc2S1 CHEMBL43905 Log Ki 0.08913 nM
Cc1c(-c2ccccc2)oc2c(C(=O)NCCCN3CCN(c4ccccc4OCCCO[N+](=O)[O-])CC3)cccc2c1=O CHEMBL338029 Ki 0.094 nM
Cc1ccc2c(c1)C(=O)N(CCCCN1CCC(n3c(=O)oc4ccccc43)CC1)S2(=O)=O CHEMBL81006 Ki 0.099 nM
COC(=O)C1=C(C)NC(=O)N(CCCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL142981 Ki 0.1 nM
COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL141322 Ki 0.1 nM
COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCC(c3ccc(C)cc3)(c3ccccc3C)CC2)C1c1ccc(F)c(F)c1 CHEMBL145411 Ki 0.1 nM
CCC1=C(C(N)=O)C(c2ccc(F)c(F)c2)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C(=O)N1 CHEMBL356584 Kb 0.1 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc2nonc2c1 CHEMBL142743 Ki 0.1 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL298713 Ki 0.1 nM
COCC1=C(C(=O)OC)C(c2ccc(F)c(F)c2)N(C(=O)NCCCN2CCC(C#N)(c3ccccc3)CC2)C(=O)N1 CHEMBL142929 Ki 0.1 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3OC)CC2)C1c1ccc(F)c(F)c1 CHEMBL146654 Ki 0.1 nM
COCC1=C(C(=O)OC)C(c2ccc(F)c(F)c2)N(C(=O)NCCCN2CCN(c3ccccc3C(N)=O)CC2)C(=O)N1 CHEMBL142236 Ki 0.1 nM
COCC1=C(C(=O)OC)C(c2cc(F)c(F)cc2F)N(C(=O)NCCCN2CCN(c3ccccc3C(N)=O)CC2)C(=O)N1 CHEMBL145072 Ki 0.1 nM
CCOc1ccccc1N1CCN(CCCNC(=O)N2C(=O)NC(C)=C(C(=O)OC)C2c2ccc(F)c(F)c2)CC1 CHEMBL142251 Ki 0.1 nM
CCC1=C(C(=O)OC)C(c2ccc(F)cc2F)N(C(=O)NCCCN2CCN(c3ccccc3C(N)=O)CC2)C(=O)N1 CHEMBL445577 Ki 0.1 nM
CSc1ccc(C)cc1NCC1=NCCN1 CHEMBL72441 Log EC50 0.1096 nM
COc1ccc(N2C(=O)c3ccc(C(=O)NCCCN4CCN(c5ccccc5OC(C)C)CC4)cc3C2=O)cc1 CHEMBL304591 Ki 0.11 nM
O=C1c2ccccc2S(=O)(=O)N1CCCCN1CCC(n2c(=O)oc3ccccc32)CC1 CHEMBL311890 Ki 0.12 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3C(N)=O)CC2)C1c1ccc(F)c(F)c1 CHEMBL145394 Ki 0.12 nM
CN1C=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)NC1=O CHEMBL91616 Ki 0.12 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1C CHEMBL89927 Ki 0.12 nM
O=C1c2cc([N+](=O)[O-])ccc2S(=O)(=O)N1CCCCN1CCC(n2c(=O)oc3ccccc32)CC1 CHEMBL83226 Ki 0.13 nM
N#Cc1ccccc1C1CCN(CCCNC(=O)C2=CNC(=O)N[C@@H]2c2ccc(F)c(F)c2)CC1 CHEMBL90652 Ki 0.13 nM
COCC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1 CHEMBL328763 Ki 0.14 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)N(C)C(=O)N1 CHEMBL90606 Ki 0.14 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)N(C)C(=O)N1C CHEMBL90420 Ki 0.14 nM
COc1cccc2c1CC[C@H]1CN(CCn3c(=O)[nH]c4cc(C#N)ccc4c3=O)C[C@@H]21 CHEMBL62033 pA2 0.1479 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)[C@@H]1c1cccc([N+](=O)[O-])c1 CHEMBL2051956 Log Ki 0.1585 nM
COc1cccc(OC)c1OCCNCC1COc2ccccc2O1 CHEMBL25554 Log Ki 0.1585 nM
Cc1c[nH]c(=O)n(CCCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O CHEMBL55695 Log Ki 0.1585 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)[C@H]1c1cccc([N+](=O)[O-])c1 CHEMBL2303676 Ki 0.16 nM
O=C1c2ccc([N+](=O)[O-])cc2S(=O)(=O)N1CCCCN1CCC(n2c(=O)oc3ccccc32)CC1 CHEMBL82877 Ki 0.16 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)[C@H]1c1cccc([N+](=O)[O-])c1 CHEMBL405355 Ki 0.16 nM
Cc1ccc(N2C(=O)c3ccc(C(=O)NCCCN4CCN(c5ccccc5OC(C)C)CC4)cc3C2=O)cc1 CHEMBL304132 Ki 0.16 nM
Cc1c(-c2ccccc2)oc2c(C(=O)NCCCN3CCN(c4ccccc4OCc4no[n+]([O-])c4C)CC3)cccc2c1=O CHEMBL338608 Ki 0.16 nM
N#Cc1ccccc1C1(C#N)CCN(CCCNC(=O)C2=CNC(=O)N[C@@H]2c2ccc(F)c(F)c2)CC1 CHEMBL91091 Ki 0.16 nM
COCC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(C#N)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1 CHEMBL4100620 Ki 0.16 nM
COc1cc2nc(N(C)CCCCCCN(C)C(=O)c3ccco3)nc(N)c2cc1OC CHEMBL27013 Log Ki 0.166 nM
C[C@@H]1OC(=O)N(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@H]1c1ccc(F)c(F)c1 CHEMBL96467 Ki 0.17 nM
N#CC1(c2ccc(F)cc2)CCN(CCCNC(=O)C2=CNC(=O)N[C@@H]2c2ccc(F)c(F)c2)CC1 CHEMBL316100 Ki 0.17 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1 CHEMBL92328 Ki 0.17 nM
O=C1NC=C(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)N1 CHEMBL94167 Ki 0.17 nM
COCC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)cc2)NCN1 CHEMBL4062896 Ki 0.17 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)[C@H]1c1ccc([N+](=O)[O-])cc1 CHEMBL179334 Ki 0.18 nM
CC(C)Oc1ccccc1N1CCN(CCCNC(=O)c2ccc3c(c2)C(=O)N(c2ccc(N(C)C)cc2)C3=O)CC1 CHEMBL69264 Ki 0.18 nM
CN1C=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)NC1=O CHEMBL316358 Ki 0.18 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1C CHEMBL90421 Ki 0.18 nM
COc1ccccc1N1CCN(CCNc2c(C(=O)C(C)C)c(-c3ccccc3)nn(C)c2=O)CC1 CHEMBL80730 Ki 0.18 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)c(F)c3)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1C CHEMBL4081581 Ki 0.18 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C(=O)N1 CHEMBL358595 Ki 0.19 nM
CCC(=O)c1c(-c2ccccc2)nn(C)c(=O)c1NCCN1CCN(c2ccccc2OC)CC1 CHEMBL78874 Ki 0.19 nM
COc1ccc(CCN2CCC(c3nc(COCC(F)(F)F)c(-c4ccc(F)cc4)o3)CC2)cc1S(N)(=O)=O CHEMBL267336 Log Ki 0.1995 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL5483012 Ki 0.2 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(F)cc1F CHEMBL141444 Ki 0.2 nM
CCC1=C(C(N)=O)C(c2ccc(F)cc2F)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C(=O)N1 CHEMBL144925 Ki 0.2 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL145459 Ki 0.2 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC3(CC2)OC(=O)Cc2ccccc23)C1c1ccc(F)c(F)c1 CHEMBL358785 Ki 0.2 nM
COCC1=C(C(=O)OC)C(c2ccc(F)c(F)c2)N(C(=O)NCCCN2CCC(C#N)(c3cccc(F)c3)CC2)C(=O)N1 CHEMBL262217 Ki 0.2 nM
COC(=O)C1=C(C)NC(=O)N(CC(=O)NCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL144938 Ki 0.2 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC3(CC2)OCCc2ccccc23)C1c1ccc(F)c(F)c1 CHEMBL359012 Ki 0.2 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(c3ccc(F)cc3)(c3ccc(F)cc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL342126 Ki 0.2 nM
CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCC3=O)cs2)CC1 CHEMBL69848 Ki 0.2 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3Cl)CC2)C1c1ccc(F)c(F)c1 CHEMBL142398 Ki 0.2 nM
CC(C)Oc1ccccc1N1CCN(CCCNC(=O)c2ccc3c(c2)C(=O)N(c2ccc(O)cc2)C3=O)CC1 CHEMBL70892 Ki 0.2 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL342731 Ki 0.2 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3C(=O)OC)CC2)C1c1ccc(F)c(F)c1 CHEMBL145338 Ki 0.2 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1 CHEMBL43491 Ki 0.2 nM
COc1cccc(OC)c1OCCNC[C@H]1CSc2ccccc2O1 CHEMBL181215 Ki 0.2 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(N3C(=O)c4cccc(F)c4C3=O)CC2)CC1 CHEMBL243694 Ki 0.2 nM
COc1cccc2c1CC[C@H]1CN(CCn3c(=O)[nH]c4c(sc5cccnc54)c3=O)C[C@@H]21 CHEMBL40650 Ki 0.22 nM
COc1ccccc1N1CCN(CCNc2cc(-c3ccccc3)nn(C)c2=O)CC1 CHEMBL311479 Ki 0.22 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL91022 Log Ki 0.2291 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL2260360 pKi 0.2291 nM
COc1ccc(N2C(=O)c3ccc(C(=O)NC[C@H](O)CN4CCN(c5ccccc5OC(C)C)CC4)cc3C2=O)cc1 CHEMBL68203 Ki 0.23 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@@H]2CC[C@H](N3CCC(c4ccccc4C#N)CC3)C2)C(=O)N1 CHEMBL300540 Ki 0.24 nM
COCC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1 CHEMBL92951 Ki 0.24 nM
CC1=C(C(=O)NCCCN2CCC(c3ccccc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1 CHEMBL328658 Ki 0.25 nM
Cc1c[nH]c(=O)n(CCCN2CCN(c3ccccc3OCC(F)(F)F)CC2)c1=O CHEMBL56331 Ki 0.25 nM
CCCCCNC(=O)/N=C(\N)NCCCc1sc(N)nc1C CHEMBL4860528 Kd 0.25 nM
CCCCCNC(=O)/N=C(\N)NCCCc1nnc(N)s1 CHEMBL5207281 Kd 0.25 nM
N/C(=N\C(=O)NCc1ccccc1)NCCCc1nnc(N)s1 CHEMBL5206565 Kd 0.25 nM
C[C@@H](NC(=O)/N=C(\N)NCCCc1ncn[nH]1)c1ccccc1 CHEMBL5201074 Kd 0.25 nM
COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1cccc(Cl)c1 CHEMBL198860 Ki 0.251 nM
c1ccc(-c2ccsc2)c(OCC2=NCCN2)c1 CHEMBL422477 Log EC50 0.2512 nM
O=c1[nH]cc(F)c(=O)n1CCCN1CCN(c2ccc(F)cc2OCC(F)(F)F)CC1 CHEMBL417954 Log Ki 0.2512 nM
COc1cccc(OC)c1OCCNCC1CC(c2ccccc2)c2ccccc2C1=O CHEMBL44403 Log Ki 0.2512 nM
COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1ccc(Cl)cc1 CHEMBL200446 Log Ki 0.2512 nM
COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1 CHEMBL8618 Ki 0.26 nM
COc1ccccc1N1CCN(CC2OCC(c3ccccc3)(c3ccccc3)O2)CC1 CHEMBL1242352 pKi 0.263 nM
COc1ccccc1N1CCN(CC2COC(c3ccccc3)(c3ccccc3)O2)CC1 CHEMBL1946777 pKi 0.263 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c([nH]c4ccccc43)c2=O)CC1 CHEMBL301707 pKi 0.2692 nM
O=C1c2cc(F)ccc2S(=O)(=O)N1CCCCN1CCC(n2c(=O)oc3ccccc32)CC1 CHEMBL83592 Ki 0.27 nM
O=C1c2ccccc2C(=O)N1CCCCN1CCC(n2c(O)nc3ccccc32)CC1 CHEMBL311247 Ki 0.28 nM
COc1ccc(Cl)cc1N1CCN(CCNc2c(C(C)=O)c(-c3ccccc3)nn(C)c2=O)CC1 CHEMBL80458 Ki 0.28 nM
COc1cc2nc(N3CCN(C(=O)CC4CCSS4)CC3)nc(N)c2cc1OC CHEMBL178673 Log Ki 0.2884 nM
Cc1ccc(N2C(=O)c3ccc(C(=O)NC[C@H](O)CN4CCN(c5ccccc5OC(C)C)CC4)cc3C2=O)cc1 CHEMBL431362 Ki 0.29 nM
COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCC(c3ccccc3OC)CC2)C1c1ccc(F)c(F)c1 CHEMBL145770 Ki 0.3 nM
CCOC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL142957 Ki 0.3 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC3(CC2)OCc2ccccc23)C1c1ccc(F)c(F)c1 CHEMBL145170 Ki 0.3 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(OC(C)=O)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL342543 Ki 0.3 nM
CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)s2)CC1 CHEMBL305029 Ki 0.3 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3C)CC2)C1c1ccc(F)c(F)c1 CHEMBL344525 Ki 0.3 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3C(N)=O)CC2)C1c1cc(F)c(F)c(F)c1 CHEMBL357172 Ki 0.3 nM
CN1C=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)N(C)C1=O CHEMBL93843 Ki 0.3 nM
CC(=O)c1c(-c2ccccc2)nn(C)c(=O)c1NCCN1CCN(c2ccccc2Cl)CC1 CHEMBL310599 Ki 0.3 nM
CCN(CC)c1ccc2cc(-n3cc(C(=O)N4CCN(c5nc(N)c6cc(OC)c(OC)cc6n5)CC4)nn3)c(=O)oc2c1 CHEMBL3582270 Ki 0.3 nM
COc1ccc(F)cc1OCCNC(C)Cc1cc(C(N)=O)c2c(ccn2CCCO)c1 CHEMBL3810110 IC50 0.3 nM
Cc1cc(C(C)(C)C)cc(C)c1CC1=NCCN1 CHEMBL312448 AC50 0.3 nM
COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1cccc([N+](=O)[O-])c1 CHEMBL197442 Ki 0.316 nM
Cc1n[nH]c(=O)n(CCCN2CCN(c3ccccc3OCC(F)(F)F)CC2)c1=O CHEMBL55290 Log Ki 0.3162 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL290860 Ki 0.32 nM
CC(=O)c1c(-c2ccccc2)nn(C)c(=O)c1NCCN1CCN(c2ccccc2F)CC1 CHEMBL420205 Ki 0.32 nM
COc1cc2nc(N(C)CCCCCCN(C)C(=O)c3cccc(CN(C)C)c3)nc(N)c2cc1OC CHEMBL341665 Log Ki 0.3236 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)CCCC(=O)NCc5ccccc5)cc43)c2=O)CC1 CHEMBL3298750 pKi 0.3236 nM
COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL145746 Ki 0.33 nM
CC(C)Oc1ccccc1N1CCN(C[C@@H](O)CNC(=O)c2ccc3c(c2)C(=O)N(c2ccc(N(C)C)cc2)C3=O)CC1 CHEMBL309106 Ki 0.33 nM
COc1cccc2c1CCCC2CCCN1CCN(c2ccccn2)CC1 CHEMBL444590 Ki 0.33 nM
COc1ccc(C[C@@H](C)NCCOc2ccccc2OC(C)C)cc1S(N)(=O)=O CHEMBL1630938 pKi 0.3388 nM
COc1ccccc1N1CCN(CCCNC(=O)c2cccc3c(=O)c(C)c(-c4ccccc4)oc23)CC1 CHEMBL278865 Ki 0.34 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3sccc3c2=O)CC1 CHEMBL13735 Ki 0.344 nM
COc1ccc(C[C@@H](C)NCCOc2ccccc2OCc2ccccc2)cc1S(N)(=O)=O CHEMBL1630939 pKi 0.3467 nM
COc1cccc(OC)c1OCCNC[C@@H]1Oc2ccccc2O[C@H]1c1ccc(C)cc1 CHEMBL72657 Ki 0.35 nM
COc1cccc2c1CC[C@H]1CN(CCn3c(=O)[nH]c4c(OC)c(OC)ccc4c3=O)C[C@@H]21 CHEMBL293695 pA2 0.3548 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)C(C(=O)NCCCN2CCC(c3ccccn3)CC2)C(=O)N1 CHEMBL265001 Ki 0.36 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)NCCCN2CCC(c3ccccn3)CC2)C(=O)N1 CHEMBL182998 Ki 0.36 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@@H]2CC[C@@H](N3CCC(C#N)(c4ccccc4)CC3)C2)C(=O)N1 CHEMBL433284 Ki 0.37 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@@H]2CC[C@@H](N3CCC(c4ccccn4)CC3)C2)C(=O)N1 CHEMBL429697 Ki 0.38 nM
CC(C)Oc1ccccc1N1CCN(CCc2ccc3c(c2)OCO3)CC1 CHEMBL3938038 pKi 0.389 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1C CHEMBL89965 Ki 0.39 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1 CHEMBL91405 Ki 0.39 nM
COc1c(C)c(C)c(O)c(C)c1CN(C)CCOc1cc(C)c(O)cc1C(C)C CHEMBL25300 Log Ki 0.3981 nM
COc1cccc(OC)c1OCCNCCOc1ccccc1Cc1ccccc1 CHEMBL42558 Log Ki 0.3981 nM
COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1cccc(C)c1 CHEMBL199080 Log Ki 0.3981 nM
COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCN(c3ccccc3OC)CC2)C1c1ccc(F)c(F)c1 CHEMBL145587 Ki 0.4 nM
COCC1=C(C(=O)OC)C(c2ccc(F)c(F)c2)N(CCCCCN2CCC(C#N)(c3ccccc3)CC2)C(C)=N1 CHEMBL141604 Ki 0.4 nM
COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCC(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL359421 Ki 0.4 nM
COCC1=NC(C)=C(C(=O)OC)C(c2ccc(F)c(F)c2)N1CCCCCN1CCC(C#N)(c2ccccc2)CC1 CHEMBL144534 Ki 0.4 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@@H]2CC[C@H](N3CCC(c4ccccn4)CC3)C2)C(=O)N1 CHEMBL293515 Ki 0.4 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)N2C(=O)NC3=C(C(=O)OC3)C2c2ccc(F)c(F)c2)CC1 CHEMBL300222 Ki 0.4 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL142383 Ki 0.4 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC3(CCCc4ccccc43)CC2)C1c1ccc(F)c(F)c1 CHEMBL344339 Ki 0.4 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1cccc([N+](=O)[O-])c1 CHEMBL3392247 Ki 0.4 nM
CC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3C(N)=O)CC2)C1c1cc(F)c(F)c(F)c1 CHEMBL358795 Ki 0.4 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(COCCN)N1 CHEMBL323579 Ki 0.4 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1 CHEMBL43860 Ki 0.4 nM
CCC1=C(C(N)=O)[C@H](c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(COCCN)N1 CHEMBL180932 Ki 0.4 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(N3C(=O)c4ccncc4C3=O)CC2)CC1 CHEMBL243229 Ki 0.4 nM
c1ccc([C@@H]2Cc3nccn3C2)c(-c2cncnc2)c1 CHEMBL513691 EC50 0.4 nM
COc1cccc(OC)c1OCCNC[C@H]1COc2ccccc2O1 CHEMBL215421 Log Ki 0.4074 nM
COc1cccc(OC)c1OCCNC[C@H]1COc2ccccc2O1 CHEMBL1182155 pKi 0.4074 nM
COc1cccc(OC)c1OCCNC[C@H]1COc2ccccc2O1 CHEMBL3741808 pKi 0.4074 nM
CC(C)Oc1ccccc1N1CCN(CCCNC(=O)c2ccc3c(c2)C(=O)N(c2cccc(F)c2)C3=O)CC1 CHEMBL67552 Ki 0.41 nM
COc1cc2nc(N(C)CCSSCCN(C)C(=O)c3ccco3)nc(N)c2cc1OC CHEMBL29591 Log Ki 0.4169 nM
COCC1=C(C(=O)NCCCN2CCC(c3ccccc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1 CHEMBL327716 Ki 0.42 nM
CSc1ccc(Cl)cc1NCC1=NCCN1 CHEMBL70751 Log EC50 0.4365 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@H]2CC[C@@H](N3CCN(c4ccccc4C#N)CC3)C2)C(=O)N1 CHEMBL300821 Ki 0.44 nM
COc1ccc(Cl)cc1N1CCN(CCCNc2c(C(C)=O)c(-c3ccccc3)nn(C)c2=O)CC1 CHEMBL77618 Ki 0.44 nM
COCC1=C(C(=O)NCCCN2CCC(c3ccccn3)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1 CHEMBL91125 Ki 0.45 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@@H]2CC[C@@H](N3CCC(c4ccccc4C#N)CC3)C2)C(=O)N1 CHEMBL262002 Ki 0.46 nM
CC(C)Oc1ccccc1N1CCN(C[C@@H](O)CNC(=O)c2ccc3c(c2)C(=O)N(c2ccc(O)cc2)C3=O)CC1 CHEMBL304977 Ki 0.46 nM
c1coc(-c2ccccc2NCC2=NCCN2)c1 CHEMBL152155 Log EC50 0.4677 nM
COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1ccccc1 CHEMBL43116 Log Ki 0.4677 nM
Cc1ccc(C2(c3ccc(C)cc3)CC(=O)N(CCCN3CCC(C#N)(c4ccccc4Cl)CC3)C2=O)cc1 CHEMBL62045 Ki 0.48 nM
COc1ccc2ccoc2c1OCCNC[C@H]1COc2ccccc2O1 CHEMBL2419769 pKi 0.4898 nM
COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(F)cc1F CHEMBL357842 Ki 0.5 nM
COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCN(c3ccccc3C(=O)OC)CC2)C1c1ccc(F)c(F)c1 CHEMBL436407 Ki 0.5 nM
COCC1=C(C(=O)OC)C(c2ccc(F)c(F)c2)N(C(=O)NCCCN2CCC(C)(c3ccccc3)CC2)C(=O)N1 CHEMBL142243 Ki 0.5 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL146109 Ki 0.5 nM
CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)cs2)CC1 CHEMBL67713 Ki 0.5 nM
c1ccc(-c2ccoc2)c(OCC2=NCCN2)c1 CHEMBL142784 Log EC50 0.5012 nM
Cc1c[nH]c(=O)n(CCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O CHEMBL293149 Log Ki 0.5012 nM
COc1cc2nc(N3CCN(C(=O)OCc4ccccc4)[C@@H]4CCCC[C@@H]43)nc(N)c2cc1OC CHEMBL4128084 pKi 0.5012 nM
CCOC(=O)[C@@H]1CN(CCCCN2C(=O)c3cc(Cl)ccc3S2(=O)=O)CC[C@@H]1c1ccccc1 CHEMBL82267 Ki 0.51 nM
COc1cccc(OC)c1OCCNCC1Cc2ccccc2C(c2ccccc2)C1 CHEMBL42231 Log Ki 0.5129 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)CC2)C1c1ccc(Cl)c([N+](=O)[O-])c1 CHEMBL327931 Log Ki 0.5248 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)CC2)C1c1ccc(Cl)c([N+](=O)[O-])c1 CHEMBL2260370 pKi 0.5248 nM
COc1ccc(Cl)cc1N1CCN(CCCNc2c(C(C)=O)c(C)nn(C)c2=O)CC1 CHEMBL80599 Ki 0.53 nM
COc1cc2nc(N3CCN(C(=O)C4COc5ccccc5O4)CC3)nc(N)c2cc1OC CHEMBL707 Log Ki 0.537 nM
COc1cccc2c1CCCC2CCCNCCOc1ccccn1 CHEMBL344432 Ki 0.55 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3cccc(Cl)c3F)CC2)CC1 CHEMBL393105 Ki 0.56 nM
COc1cc2ncn(CCN3C[C@@H]4CCc5c(OC)cccc5[C@@H]4C3)c(=O)c2cc1OC CHEMBL445325 pA2 0.5888 nM
COc1cc2nc(N3CCN(C(=O)c4ccco4)[C@@H]4CCCC[C@@H]43)nc(N)c2cc1OC CHEMBL342062 pKi 0.5888 nM
COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCN(c3ccccc3C(N)=O)CC2)C1c1ccc(F)c(F)c1 CHEMBL357828 Ki 0.6 nM
O=C1OCC2=C1C(c1ccc(F)c(F)c1)N(C(=O)NCCCN1CCN(c3ccccc3[N+](=O)[O-])CC1)C(=O)N2 CHEMBL51871 Ki 0.6 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@H]2CC[C@@H](N3CCC(c4ccccc4C#N)CC3)C2)C(=O)N1 CHEMBL292365 Ki 0.6 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3O)CC2)C1c1ccc(F)c(F)c1 CHEMBL141821 Ki 0.6 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1C CHEMBL91403 Ki 0.6 nM
CC(C)(Cc1c[nH]c2ccc(Cl)cc12)NCCOc1ccccc1OCC1CC1 CHEMBL88272 Ki 0.6 nM
Cc1ccc(N(CC2=NCCN2)c2cccc(O)c2)cc1 CHEMBL597 Ki 0.6 nM
c1ccc2c(CC3=NCCN3)cccc2c1 CHEMBL761 AC50 0.6 nM
COc1ccc(C[C@@H](C)NCCOc2ccccc2OCC(F)(F)F)cc1S(N)(=O)=O CHEMBL1630940 pKi 0.6026 nM
COc1ccccc1N1CCN(CCNc2c(C(C)=O)c(-c3ccccc3)nn(C)c2=O)CC1 CHEMBL80641 Ki 0.63 nM
COc1ccccc1N1CCN(CCCNc2c(C)c(=O)n(C)c(=O)n2C)CC1 CHEMBL420060 Log Ki 0.631 nM
COc1ccccc1N1CCN(C[C@H]2CO[C@@](CN3CCCCCC3=O)(c3ccccc3)O2)CC1 CHEMBL1242632 pKi 0.631 nM
COc1cc2nc(N3CCC[C@H](NC(=O)c4ccco4)C3)nc(N)c2cc1OC CHEMBL4161165 pKi 0.631 nM
COc1ccccc1N1CCN(CC2CCC(c3ccccc3)(c3ccccc3)O2)CC1 CHEMBL1946780 pKi 0.6457 nM
COc1cccc(OC)c1OCCNC[C@H]1COc2cccc(F)c2O1 CHEMBL2153557 pKi 0.6457 nM
CC(C)Oc1ccccc1N1CCN(CCCNC(=O)CN2CCCCC2=O)CC1 CHEMBL12062 Ki 0.65 nM
Cc1ccc(N2C(=O)c3ccc(C(=O)NCC(O)CN4CCN(c5ccccc5OC(C)C)CC4)cc3C2=O)cc1 CHEMBL69295 Ki 0.66 nM
CCC1=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C(c2ccc([N+](=O)[O-])cc2)/C(=C(\O)OC)C(C)=N1 CHEMBL25121 Log Ki 0.6607 nM
c1ccc(-c2ncco2)c(NCC2=NCCN2)c1 CHEMBL155326 Log EC50 0.6607 nM
Cc1noc(C)c1S(=O)(=O)Nc1ccc2c(c1)C(=O)CC1(CCN(CCc3cccc4ccccc34)CC1)O2 CHEMBL101610 Ki 0.69 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)N2C(=O)NC(C)=C(C(N)=O)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL145562 Ki 0.7 nM
CCC1=C(C(N)=O)C(c2ccc(F)cc2F)N(C(=O)NCCCN2CCC(C#N)(c3ccccc3)CC2)C(=O)N1 CHEMBL357628 Ki 0.7 nM
CC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3C(N)=O)CC2)C1c1ccc(F)c(F)c1 CHEMBL145574 Ki 0.7 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3cccc(Cl)c3)CC2)C1c1ccc(F)c(F)c1 CHEMBL145443 Ki 0.7 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1C CHEMBL287791 Ki 0.7 nM
Cc1c(-c2ccccc2)oc2c(C(=O)NCCCN3CCN(c4ccccc4OCc4no[n+]([O-])c4C#N)CC3)cccc2c1=O CHEMBL125989 Ki 0.73 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3cccc(F)c3)CC2)CC1 CHEMBL232780 Ki 0.73 nM
COC(=O)N1C(=O)N(C)C(C)=C(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@H]1c1ccc(F)c(F)c1 CHEMBL93623 Ki 0.75 nM
CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2ccc3c(c2)C(=O)N(c2cccc(Cl)c2)C3=O)CC1 CHEMBL71580 Ki 0.76 nM
COc1ccc(N2C(=O)c3ccc(C(=O)NCC(O)CN4CCN(c5ccccc5OC(C)C)CC4)cc3C2=O)cc1 CHEMBL302940 Ki 0.77 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3ccccc3C#N)CC2)CC1 CHEMBL234680 Ki 0.77 nM
COC(=O)c1ccccc1NCC1=NCCN1 CHEMBL414185 Log EC50 0.7943 nM
c1ccc(-c2nc[nH]n2)c(NCC2=NCCN2)c1 CHEMBL17491 Log EC50 0.7943 nM
c1ccc(-c2ccno2)c(NCC2=NCCN2)c1 CHEMBL155327 Log EC50 0.7943 nM
Cc1c[nH]c(=O)n(CC2(CN3CCN(c4ccccc4OCC(F)(F)F)CC3)CC2)c1=O CHEMBL55629 Log Ki 0.7943 nM
CCc1c[nH]c(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O CHEMBL53675 Log Ki 0.7943 nM
CCC1=C(C(=O)OC)C(c2ccc([N+](=O)[O-])cc2)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C(=O)N1 CHEMBL123012 Ki 0.8 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccc(Cl)cc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL142307 Ki 0.8 nM
CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2ccc3c(c2)C(=O)N(c2ccc(N(C)C)cc2)C3=O)CC1 CHEMBL67648 Ki 0.8 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1C CHEMBL288772 Ki 0.8 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(N3C(=O)c4cccnc4C3=O)CC2)CC1 CHEMBL243228 Ki 0.8 nM
O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cc2ccccc2s1 CHEMBL3290012 Ki 0.8 nM
COc1cc2nc(N3CCN(C(=O)C4CCSS4)CC3)nc(N)c2cc1OC CHEMBL175934 Log Ki 0.8128 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)NC(C)=C(C(N)=O)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL356829 Ki 0.84 nM
Cc1ccsc1-c1ccccc1NCC1=NCCN1 CHEMBL152693 Log EC50 0.8511 nM
COc1ccccc1N1CCN(CCCOc2ccc3c(C)cc(=O)oc3c2)CC1 CHEMBL51767 pA2 0.8511 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3sc(-c4ccccc4)cc3c2=O)CC1 CHEMBL13903 Ki 0.868 nM
COc1ccccc1N1CCN(C[C@H]2CO[C@@](CN3CCCCC3=O)(c3ccccc3)O2)CC1 CHEMBL1242541 pKi 0.871 nM
COc1cc2nc(N3CCN(C(=O)COc4c(OC)cccc4C(C)C)[C@H]4CCCC[C@H]43)nc(N)c2cc1OC CHEMBL4129291 pKi 0.871 nM
CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2ccc3c(c2)C(=O)N(c2ccc(O)cc2)C3=O)CC1 CHEMBL68604 Ki 0.88 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3ccccc3F)CC2)CC1 CHEMBL234681 Ki 0.88 nM
COc1ccccc1N1CCN(CCCNc2c(C(C)=O)c(C)nn(C)c2=O)CC1 CHEMBL79161 Ki 0.89 nM
COc1cccc(OC)c1OCCNC[C@H]1COc2cccc(Cl)c2O1 CHEMBL2153555 pKi 0.8913 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)N2C(=O)NC3=C(C(=O)OC3)C2c2ccc3nonc3c2)CC1 CHEMBL299539 Ki 0.9 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@@H]2CC[C@@H](N3CCN(c4ccccc4C#N)CC3)C2)C(=O)N1 CHEMBL56974 Ki 0.9 nM
C[C@H]1OC(=O)N(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@H]1c1ccc(F)c(F)c1 CHEMBL2114249 Ki 0.9 nM
Cc1cccc(N2C(=O)c3ccc(C(=O)NCC(O)CN4CCN(c5ccccc5OC(C)C)CC4)cc3C2=O)c1 CHEMBL303248 Ki 0.9 nM
CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2ccc3c(c2)C(=O)N(c2ccccc2)C3=O)CC1 CHEMBL69143 Ki 0.9 nM
CC(C)Oc1ccccc1N1CCN(Cc2nc(CN3CCCC3=O)cs2)CC1 CHEMBL310768 Ki 0.9 nM
COc1ccc(C)cc1S(=O)(=O)N[C@H]1CC[C@H](N2CCN(c3ccccc3OC(C)C)CC2)CC1 CHEMBL233623 Ki 0.9 nM
O=C1NC=C(C(=O)NCCCN2CCC(O)(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)N1 CHEMBL329143 Ki 0.91 nM
COc1ccc(S(=O)(=O)N[C@H]2CC[C@@H](N3CCC(c4ccccc4OC4CC4)CC3)CC2)cc1OC CHEMBL229085 Ki 0.91 nM
COc1cccc(OC)c1OCCNC[C@H]1COc2cccc(OC)c2O1 CHEMBL2153553 pKi 0.912 nM
COc1ccccc1N1CCN(CCn2c(C)nc3c(sc4ccc(NC(=O)CCCC(=O)NCCc5ccccc5)cc43)c2=O)CC1 CHEMBL3298023 pKi 0.912 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)CCCC(=O)N(C)Cc5ccccc5)cc43)c2=O)CC1 CHEMBL3297829 pKi 0.9333 nM
CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2ccc3c(c2)C(=O)N(c2ccc(Cl)cc2)C3=O)CC1 CHEMBL68601 Ki 0.95 nM
COc1cc2[nH]c(=O)n(CCN3C[C@@H]4CCc5c(OC)cccc5[C@@H]4C3)c(=O)c2cc1OC CHEMBL291303 pA2 0.9772 nM
COc1ccc(N2C(=O)c3ccc(C(=O)NCC(O)CN4CCN(c5ccccc5OC(C)C)CC4)cc3C2=O)cc1OC CHEMBL70095 Ki 0.98 nM
Cc1ccc(C(C(=O)NCCCN2CCC(C#N)(c3ccccc3Cl)CC2)c2ccc(C)cc2)cc1 CHEMBL44294 Ki 0.99 nM
O=C1NCCN1CCN1CCC(c2cn(-c3ccc(F)cc3)c3ccc(Cl)cc23)CC1 CHEMBL12713 Activity 0.99 nM
COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCC(C#N)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL145001 Ki 1.0 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@@H]2CC[C@H](N3CCC(C#N)(c4ccccc4)CC3)C2)C(=O)N1 CHEMBL1789975 Ki 1.0 nM
Cc1c[nH]c(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O CHEMBL24777 Log Ki 1.0 nM
CC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(C)N1 CHEMBL279436 Log Ki 1.0 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(OC)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL144965 Ki 1.0 nM
c1csc(-c2ccccc2OCC2=NCCN2)c1 CHEMBL143801 Log EC50 1.0 nM
c1ccc(-c2cc[nH]n2)c(NCC2=NCCN2)c1 CHEMBL277375 Log EC50 1.0 nM
O=C1CCNC(=O)N1CCCN1CCN(c2ccc(F)cc2OCC(F)(F)F)CC1 CHEMBL59153 Log Ki 1.0 nM
O=c1[nH]cc(Cl)c(=O)n1CCCN1CCN(c2ccc(F)cc2OCC(F)(F)F)CC1 CHEMBL298838 Log Ki 1.0 nM
CC1=C(C(=O)NCCCN2CCC(c3ccccc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1 CHEMBL42640 Ki 1.0 nM
COc1ccc(Cl)cc1N1CCN(CCNc2cc(-c3ccccc3)nn(C)c2=O)CC1 CHEMBL81486 Ki 1.0 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3F)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1 CHEMBL295001 Ki 1.0 nM
COc1ccccc1N1CCN(CCN2C(=O)c3ccccc3C(C)(C)C2=O)CC1 CHEMBL362051 Ki 1.0 nM
COc1ccc([N+](=O)[O-])cc1S(=O)(=O)N[C@H]1CC[C@H](N2CCN(c3ccccc3OC(C)C)CC2)CC1 CHEMBL234422 Ki 1.0 nM
COc1ccc(Cl)cc1S(=O)(=O)N[C@H]1CC[C@@H](N2CCN(c3ccccc3OC(C)C)CC2)CC1 CHEMBL233816 Ki 1.0 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3ccccc3[N+](=O)[O-])CC2)CC1 CHEMBL232593 Ki 1.0 nM
c1cncc(-c2ccccc2[C@@H]2Cc3nccn3C2)c1 CHEMBL468711 EC50 1.0 nM
Fc1ccc(-c2cncnc2)c(C2Cc3nccn3C2)c1 CHEMBL506744 EC50 1.0 nM
COc1ccccc1N1CCN(CCn2c(C)nc3c(sc4ccc(NC(=O)CCCNC(=O)Cc5ccccc5)cc43)c2=O)CC1 CHEMBL3298024 pKi 1.0 nM
CC(C)Oc1ccccc1N1CCN(C[C@@H](O)CNC(=O)c2ccc3c(c2)C(=O)N(c2cccc(F)c2)C3=O)CC1 CHEMBL303627 Ki 1.02 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(CC)N1 CHEMBL91550 Log Ki 1.072 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)c5ccccc5)cc43)c2=O)CC1 CHEMBL3298745 pKi 1.096 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)CCC(=O)NCc5ccccc5)cc43)c2=O)CC1 CHEMBL3298749 pKi 1.096 nM
Cc1ccc(C(C(=O)NCCCN2CCN(c3ccccc3C)CC2)c2ccc(C)cc2)cc1 CHEMBL415887 Ki 1.1 nM
COC(=O)C1=C(C)N=C(C)N(CCCCCN2CCC(c3ccccc3C(F)(F)F)CC2)C1c1ccc(F)c(F)c1 CHEMBL142606 Ki 1.1 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)N2C(=O)NC3=C(C(=O)OC3)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL301077 Ki 1.1 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1cccc(Cl)c1 CHEMBL143066 Ki 1.1 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC3(CCc4ccccc43)CC2)C1c1ccc(F)c(F)c1 CHEMBL424494 Ki 1.1 nM
CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCC3=O)no2)CC1 CHEMBL309969 Ki 1.1 nM
COc1ccccc1N1CCN(CCNc2ccc3c4c(=O)n(C)nc(Cl)c4cn3n2)CC1 CHEMBL301078 Ki 1.1 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3F)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1C CHEMBL295395 Ki 1.1 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc2c(c1)OCO2 CHEMBL91415 Log Ki 1.122 nM
COc1cccc([N+](=O)[O-])c1OCCNCCOc1ccccc1OCc1ccccc1 CHEMBL1254743 pKi 1.122 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc2c(c1)OCO2 CHEMBL2260366 pKi 1.122 nM
CCOc1ccccc1N1CCN(CCc2ccc3c(c2)OCO3)CC1 CHEMBL3917716 pKi 1.122 nM
CCOc1ccccc1N1CCN(CCc2ccc(OC)cc2)CC1 CHEMBL3930616 pKi 1.122 nM
CC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL89685 Log Ki 1.175 nM
CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2ccc3c(c2)C(=O)N(c2ccc(Cl)c(Cl)c2)C3=O)CC1 CHEMBL302092 Ki 1.19 nM
COC(=O)C1=C(C)N=C(C)N(CCC[C@H](C)CN2CCC(C#N)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL145178 Ki 1.2 nM
CCC1=C(C(=O)NC)C(c2ccc([N+](=O)[O-])cc2)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C(=O)N1 CHEMBL145752 Ki 1.2 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(F)cc1 CHEMBL145610 Ki 1.2 nM
Cc1ccc2oc(=O)n(C3CCN(CCCCN4C(=O)c5ccccc5S4(=O)=O)CC3)c2c1 CHEMBL432947 Ki 1.2 nM
CC(C)Oc1ccccc1N1CCN(Cc2nc(CN3CCCCC3=O)cs2)CC1 CHEMBL310890 Ki 1.2 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@@H](NS(=O)(=O)Cc3ccccc3)CC2)CC1 CHEMBL234649 Ki 1.2 nM
COc1ccc(S(=O)(=O)N[C@H]2CC[C@@H](N3CCN(c4ccccc4OCC(F)(F)F)CC3)CC2)cc1OC CHEMBL438673 Ki 1.2 nM
NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL1437 AC50 1.2 nM
COc1cccc(-c2ccccc2)c1OCCNC[C@H]1COc2ccccc2O1 CHEMBL215151 Log Ki 1.202 nM
COc1cc(N2C(=O)c3ccc(C(=O)NCC(O)CN4CCN(c5ccccc5OC(C)C)CC4)cc3C2=O)cc(OC)c1OC CHEMBL68913 Ki 1.22 nM
CCC(C)OC(=O)c1ccccc1NCC1=NCCN1 CHEMBL97859 Log EC50 1.259 nM
CCC1=NC(CC)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C(c2ccc([N+](=O)[O-])cc2)/C1=C(\O)OC CHEMBL276932 Log Ki 1.259 nM
c1c[nH]c(-c2ccccc2OCC2=NCCN2)c1 CHEMBL357129 Log EC50 1.259 nM
c1coc(-c2ccccc2OCC2=NCCN2)c1 CHEMBL279136 Log EC50 1.259 nM
CCn1ncnc1-c1ccccc1NCC1=NCCN1 CHEMBL273316 Log EC50 1.259 nM
c1ccc(-c2cn[nH]c2)c(NCC2=NCCN2)c1 CHEMBL275844 Log EC50 1.259 nM
O=c1cc[nH]c(=O)n1CCCN1CCN(c2ccc(F)cc2OCC(F)(F)F)CC1 CHEMBL299452 Log Ki 1.259 nM
COc1cc2nc(N3CCN(C4=CC(=O)c5ccccc5C4=O)CC3)nc(N)c2cc1OC CHEMBL179743 Log Ki 1.259 nM
COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1ccc([N+](=O)[O-])cc1 CHEMBL196817 Log Ki 1.259 nM
Cc1ccc(C(C(=O)NCCCN2CCC(C#N)(c3ccccc3C)CC2)c2ccc(C)cc2)cc1 CHEMBL298058 Ki 1.3 nM
CCC1=C(C(N)=O)C(c2ccc(F)cc2F)N(C(=O)NCCCN2CCN(c3ccccc3C(N)=O)CC2)C(=O)N1 CHEMBL142718 Ki 1.3 nM
COc1ccc(Cl)cc1S(=O)(=O)N[C@H]1CC[C@@H](N2CCC(c3ccccc3OC3CC3)CC2)CC1 CHEMBL388897 Ki 1.3 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3ccc(F)cc3)CC2)CC1 CHEMBL428197 Ki 1.3 nM
COc1cc2nc(N3CCN(C(=O)c4cn(-c5cc6ccc(O)cc6oc5=O)nn4)CC3)nc(N)c2cc1OC CHEMBL3582269 Ki 1.3 nM
CC(Cc1cc(C(N)=O)c2c(ccn2CCCO)c1)NCCOc1cc(Cl)ccc1OCC(F)(F)F CHEMBL3810145 IC50 1.3 nM
COc1ccc(Cl)cc1N1CCN(CCn2c(C)nc3c([nH]c4ccccc43)c2=O)CC1 CHEMBL220515 Log Ki 1.318 nM
CC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)CC2)=C(COCCN)N1 CHEMBL95548 Ki 1.37 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(C)cc1 CHEMBL315914 Log Ki 1.38 nM
COc1ccccc1N1CCN(C[C@H]2CO[C@](CN3CCCC3=O)(c3ccccc3)O2)CC1 CHEMBL1242444 pKi 1.38 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(C)cc1 CHEMBL2260365 pKi 1.38 nM
COc1cc2nc(N3CCN(c4ccco4)CC3)nc(N)c2cc1OC CHEMBL137598 Ki 1.39 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1 CHEMBL42335 Ki 1.4 nM
COc1ccccc1N1CCN(CCn2nc(-c3ccccc3)c3c(C)onc3c2=O)CC1 CHEMBL303464 Ki 1.4 nM
O=C(NCCCCN1CCN(c2csc3cc(F)ccc23)CC1)c1cnccn1 CHEMBL369520 Ki 1.4 nM
CC(C)Oc1ccccc1C1CCN([C@H]2CC[C@H](NS(=O)(=O)c3ccc(F)c(F)c3)CC2)CC1 CHEMBL229084 Ki 1.4 nM
CN1CC2c3ccccc3Oc3ccc(Cl)cc3C2C1 CHEMBL3187365 AC50 1.4 nM
COc1cc2nc(N3CCN(C(=O)CCCCC4CCSS4)CC3)nc(N)c2cc1OC CHEMBL178923 Log Ki 1.413 nM
COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1ccccc1Cl CHEMBL200839 Log Ki 1.413 nM
Cc1ccc2c(c1)c1c(n2/C=C\c2ccccc2)CCN(C)C1 CHEMBL605405 pKi 1.413 nM
O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2cc(Cl)ccc2Cl)CC1 CHEMBL59262 pKi 1.445 nM
COc1ccccc1N1C(=O)c2ccc(C(=O)NCC(O)CN3CCN(c4ccccc4OC(C)C)CC3)cc2C1=O CHEMBL68565 Ki 1.47 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])c(OC)c1 CHEMBL313160 Log Ki 1.479 nM
COc1ccccc1N1CCN(CCn2c(C)nc3c(sc4ccccc43)c2=O)CC1 CHEMBL220221 Log Ki 1.479 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])c(OC)c1 CHEMBL2260368 pKi 1.479 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)Cc5ccccc5)cc43)c2=O)CC1 CHEMBL3298746 pKi 1.479 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1cccc(F)c1 CHEMBL356978 Ki 1.5 nM
CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2ccc3c(c2)C(=O)N(c2ccc(F)cc2)C3=O)CC1 CHEMBL308671 Ki 1.5 nM
CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2ccc3c(c2)C(=O)N(c2cccc(F)c2)C3=O)CC1 CHEMBL302246 Ki 1.5 nM
Cc1ccc(S(=O)(=O)N[C@H]2CC[C@H](N3CCN(c4ccccc4OC(C)C)CC3)CC2)cc1Cl CHEMBL234609 Ki 1.5 nM
COc1ccccc1N1CCN(CCCNc2c(C(C)=O)c(-c3ccccc3)nn(C)c2=O)CC1 CHEMBL80260 Ki 1.51 nM
COc1ccc(SC)c(NCC2=NCCN2)c1 CHEMBL70691 Log EC50 1.585 nM
COc1c[nH]c(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O CHEMBL418112 Log Ki 1.585 nM
Cc1cc(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c(=O)[nH]1 CHEMBL56489 Log Ki 1.585 nM
COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1ccccc1C CHEMBL382972 Log Ki 1.585 nM
COc1ccc2ccccc2c1OCCNC[C@H]1COc2ccccc2O1 CHEMBL217469 Log Ki 1.585 nM
COc1ccc2ccccc2c1OCCNC[C@H]1COc2ccccc2O1 CHEMBL1182182 pKi 1.585 nM
COc1cc2nc(N3CCN(C(=O)CC(c4ccccc4)c4ccccc4)CC3)nc(N)c2cc1OC CHEMBL137903 Ki 1.59 nM
COC(=O)C1=C(C)N=C(C)N(CCC[C@H](C)CN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL357131 Ki 1.6 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@@H]2CC[C@H](N3CCN(c4ccccc4C#N)CC3)C2)C(=O)N1 CHEMBL300766 Ki 1.6 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3ccc(Cl)cc3Cl)CC2)CC1 CHEMBL393104 Ki 1.6 nM
COc1ccc(Br)cc1S(=O)(=O)N[C@H]1CC[C@@H](N2CCN(c3ccccc3OC(C)C)CC2)CC1 CHEMBL233849 Ki 1.6 nM
COc1ccc(S(=O)(=O)N[C@H]2CC[C@@H](N3CCN(c4ccccc4OC(C)C)CC3)CC2)cc1OC CHEMBL391530 Ki 1.6 nM
COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(F)cc2)c2ccccc2)CC1 CHEMBL4544086 Ki 1.6 nM
COc1cccc2c(CCCN3CCN(c4ccccn4)CC3)cccc12 CHEMBL139505 Ki 1.62 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)CCCC(=O)NCCc5ccccc5)cc43)c2=O)CC1 CHEMBL3298017 pKi 1.622 nM
COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC CHEMBL1558 Ki 1.626 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)CCCN(C)C)cc43)c2=O)CC1 CHEMBL3298019 pKi 1.698 nM
COCC1=C(C(=O)OC)C(c2cc(F)c(F)c(F)c2)N(C(=O)N2CCC(N3CCC(C(=O)OC)(c4ccccc4)CC3)CC2)C(=O)N1 CHEMBL145553 Ki 1.7 nM
CCC1=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C(c2ccc([N+](=O)[O-])cc2)C(C(N)=O)=C(COCCN)N1 CHEMBL432026 Ki 1.7 nM
Cc1ccc(C2(c3ccc(C)cc3)CC(=O)N(CCCN3CCC(C#N)(c4ccccc4C)CC3)C2=O)cc1 CHEMBL299914 Ki 1.7 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3cc(F)ccc3F)CC2)CC1 CHEMBL257097 Ki 1.7 nM
COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccccc2)c2ccccc2)CC1 CHEMBL4442460 Ki 1.7 nM
Clc1cccc(Cl)c1NC1=NCCN1 CHEMBL134 AC50 1.7 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(Cl)cc1 CHEMBL314960 Log Ki 1.778 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(Cl)cc1 CHEMBL2260359 pKi 1.778 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1cccc(C)c1 CHEMBL358489 Ki 1.8 nM
CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCCC3=O)cs2)CC1 CHEMBL421297 Ki 1.8 nM
CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2ccc3c(c2)C(=O)N(c2ccc([N+](=O)[O-])cc2)C3=O)CC1 CHEMBL68746 Ki 1.8 nM
Cc1c(-c2ccccc2)oc2c(C(=O)NCCCN3CCN(c4ccccc4OCc4no[n+]([O-])c4C(N)=O)CC3)cccc2c1=O CHEMBL125365 Ki 1.8 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1 CHEMBL288768 Ki 1.8 nM
COc1ccc(S(=O)(=O)N[C@H]2CC[C@@H](N3CCC(c4ccccc4OCC(F)(F)F)CC3)CC2)cc1OC CHEMBL228334 Ki 1.8 nM
O=S(=O)(N[C@H]1CC[C@@H](N2CCC(c3ccccc3OC3CC3)CC2)CC1)c1cc(Cl)ccc1F CHEMBL228280 Ki 1.8 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(N3C(=O)c4ccc5ccccc5c4C3=O)CC2)CC1 CHEMBL243864 Ki 1.8 nM
COc1ccc(S(=O)(=O)N[C@H]2CC[C@@H](N3CCC(c4ccccc4OC(C)C)CC3)CC2)cc1OC CHEMBL390129 Ki 1.8 nM
COc1cc(C(C)=O)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1 CHEMBL14376 AC50 1.8 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(C#N)cc1 CHEMBL89243 Log Ki 1.82 nM
COc1ccccc1N1CCN(CCCCN2C(=O)CC(c3ccccc3)CC2=O)CC1 CHEMBL1796033 pKi 1.82 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(C#N)cc1 CHEMBL2260149 pKi 1.82 nM
CC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(C)N1 CHEMBL180561 Log Ki 1.862 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(Cl)c(Cl)c1 CHEMBL327712 Log Ki 1.862 nM
COc1cc2nc(N(C)CCCCCCN(C)C(=O)C3COc4ccccc4O3)nc(N)c2cc1OC CHEMBL561851 pKi 1.862 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(Cl)c(Cl)c1 CHEMBL2260367 pKi 1.862 nM
CCCN(CCC)c1nc(N2CCN(C(=O)c3ccco3)[C@@H]3CCCC[C@@H]32)nc2cc(OC)c(OC)cc12 CHEMBL4126860 pKi 1.862 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL144989 Ki 1.9 nM
CCOC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)NC(C)=C(C(C)=O)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL347499 Ki 1.9 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1C CHEMBL291166 Ki 1.9 nM
Cc1ccc(OCC(F)(F)F)c(OCCN[C@H](C)Cc2cc(C(N)=O)c3c(ccn3CCCO)c2)c1 CHEMBL3809490 IC50 1.9 nM
CC(Cc1cc(C(N)=O)c2c(ccn2CCCO)c1)NCCOc1ccccc1OCC(F)(F)F CHEMBL3808572 IC50 1.9 nM
CCOc1ccccc1OCCNC(C)Cc1cc(C(N)=O)c2c(ccn2CCCO)c1 CHEMBL3809248 IC50 1.9 nM
Cc1cc(C(C)(C)C)c(O)c(C)c1CC1=NCCN1 CHEMBL762 AC50 1.9 nM
Cn1nc(Cl)c2cn3nc(NCCN4CCN(c5ccccc5)CC4)ccc3c2c1=O CHEMBL51074 Ki 1.93 nM
Cc1ccc(S(C)(=O)=O)c(NCC2=NCCN2)c1 CHEMBL71479 Log EC50 1.95 nM
COc1cccc(COc2ccccc2OCCNCCOc2c(OC)cccc2OC)c1 CHEMBL427552 Ki 1.99 nM
COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1ccc(C)cc1 CHEMBL200366 Ki 1.99 nM
c1cncc(-c2ccccc2OCC2=NCCN2)c1 CHEMBL356605 Log EC50 1.995 nM
Cn1ncnc1-c1ccccc1NCC1=NCCN1 CHEMBL18069 Log EC50 1.995 nM
Cc1cn(CCCN2CCN(c3ccccc3OCC(F)(F)F)CC2)c(=O)[nH]c1=O CHEMBL292403 Log Ki 1.995 nM
COc1ccc(COc2ccccc2OCCNCCOc2c(OC)cccc2OC)cc1 CHEMBL200580 Log Ki 1.995 nM
COc1ccccc1COc1ccccc1OCCNCCOc1c(OC)cccc1OC CHEMBL198431 Log Ki 1.995 nM
CCOc1ccccc1OCCNCCOc1ccccc1OCc1ccccc1 CHEMBL1254914 pKi 1.995 nM
COc1ccc2c(c1OCCNC[C@H]1COc3ccccc3O1)OCC2 CHEMBL2419771 pKi 1.995 nM
COc1ccc(CCN2CCN(c3ccccc3OC(C)C)CC2)cc1OC CHEMBL3920110 pKi 1.995 nM
COc1cc2nc(N3CCN(C(=O)C4CCCO4)CC3)nc(N)c2cc1OC CHEMBL611 Ki 2.0 nM
Cc1ccccc1C1(C#N)CCN(CCCNC(=O)C(c2ccc(F)c(F)c2)C(C)C)CC1 CHEMBL41994 Ki 2.0 nM
COc1ccc(Cl)cc1N1CCN(CCCNc2cc(-c3ccccc3)nn(C)c2=O)CC1 CHEMBL78676 Ki 2.0 nM
Cc1ccc(C(O)(C(=O)NCCCN2CCC(C#N)(c3ccccc3C)CC2)c2ccc(C)cc2)cc1 CHEMBL59590 Ki 2.0 nM
COc1ccc(Cl)cc1N1CCN(CCCNc2nccc(C(N)=O)n2)CC1 CHEMBL24981 Ki 2.0 nM
c1ccc([C@@H]2Cc3nccn3C2)c(-c2ncco2)c1 CHEMBL448802 EC50 2.0 nM
COc1cc2c3c(c1OC)-c1cc4c(cc1CC3N(C)CC2)OCO4 CHEMBL467094 Ki 2.0 nM
Cc1ccc(N2CCN(CCc3ccc(CN4C(=O)c5ccccc5C4=O)cc3)CC2)cc1 CHEMBL3740019 IC50 2.03 nM
COc1ccccc1N1CCN(C[C@H]2CO[C@@](CN3C(=O)CC4(CCCC4)CC3=O)(c3ccccc3)O2)CC1 CHEMBL1242912 pKi 2.042 nM
CC(C)Oc1ccccc1OCCNCC1COC(c2ccccc2)(c2ccccc2)O1 CHEMBL1078773 pKi 2.089 nM
CCOc1ccccc1N1CCN(CCc2ccc(OC)c(OC)c2)CC1 CHEMBL3902626 pKi 2.089 nM
COc1ccc(N2C(=O)c3ccc(C(=O)NC[C@@H](O)CN4CCN(c5ccccc5OC(C)C)CC4)cc3C2=O)cc1 CHEMBL302942 Ki 2.09 nM
CNC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL145334 Ki 2.1 nM
CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)n[nH]2)CC1 CHEMBL310471 Ki 2.1 nM
COc1cc2nc(N3CCN(C(=O)c4cc5ccc(O)cc5oc4=O)CC3)nc(N)c2cc1OC CHEMBL3582268 Ki 2.1 nM
COc1cccc(OC)c1OCCNC[C@H]1COc2cccc(O)c2O1 CHEMBL2153551 pKi 2.188 nM
CCOC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)NC(C)=C(C(N)=O)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL151878 Ki 2.19 nM
CC(=O)N1C(=O)N(C)C(C)=C(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@H]1c1ccc(F)c(F)c1 CHEMBL90453 Ki 2.2 nM
O=S(=O)(N[C@H]1CC[C@H](N2CCC(c3ccccc3OCC(F)(F)F)CC2)CC1)c1ccc2c(c1)OCCO2 CHEMBL228390 Ki 2.2 nM
Cc1ccc(OCC(F)(F)F)c(OCCNC(C)Cc2cc(C(N)=O)c3c(ccn3CCCO)c2)c1 CHEMBL3809840 IC50 2.2 nM
c1csc(-c2ccccc2NCC2=NCCN2)c1 CHEMBL346380 Log EC50 2.239 nM
COc1ccc(CCN2CCN(c3ccccc3OC(C)C)CC2)cc1 CHEMBL3976144 pKi 2.239 nM
COc1ccccc1N1CCN(CCNc2c(C(C)=O)c(C)nn(C)c2=O)CC1 CHEMBL77901 Ki 2.29 nM
CSc1ccc(F)cc1NCC1=NCCN1 CHEMBL72768 Log EC50 2.291 nM
NC(=O)c1ccccc1N1CCN(CCCNC(=O)N2C(=O)NC3=C(C(=O)OC3)C2c2ccc(F)c(F)c2)CC1 CHEMBL50081 Ki 2.3 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@H]2CC[C@H](N3CCC(C#N)(c4ccccc4)CC3)C2)C(=O)N1 CHEMBL301024 Ki 2.3 nM
CN1C=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3)CC2)[C@H](c2ccc(F)c(F)c2)NC1=O CHEMBL419497 Ki 2.3 nM
Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2 CHEMBL85 Ki 2.3 nM
COc1cccc(OC)c1OCCN[C@H]1C[C@H](c2ccccc2)c2ccccc2S1 CHEMBL2234442 Ki 2.34 nM
COc1cccc(OC)c1OCCNC[C@H]1C[C@H](c2ccccc2)c2ccccc2S1 CHEMBL40325 Log Ki 2.344 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@H]2CC[C@H](N3CCC(c4ccccc4C#N)CC3)C2)C(=O)N1 CHEMBL433832 Ki 2.4 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@H]2CC[C@@H](N3CCC(C#N)(c4ccccc4)CC3)C2)C(=O)N1 CHEMBL300355 Ki 2.4 nM
CS(=O)(=O)c1ccc2c(c1)S(=O)(=O)N(CCCCN1CCC(n3c(=O)oc4ccccc43)CC1)C2=O CHEMBL81173 Ki 2.4 nM
CNC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL147077 Ki 2.42 nM
O=C1NC=C(C(=O)NCCCN2CCC(c3ccccn3)CC2)[C@@H](c2ccc(F)c(F)c2)N1 CHEMBL90210 Ki 2.5 nM
CNC(=O)c1ccccc1NCC1=NCCN1 CHEMBL95523 Log EC50 2.512 nM
c1ccc(-c2cnccn2)c(OCC2=NCCN2)c1 CHEMBL143973 Log EC50 2.512 nM
c1ccc(-c2nccs2)c(OCC2=NCCN2)c1 CHEMBL142871 Log EC50 2.512 nM
CCn1cccc1-c1ccccc1NCC1=NCCN1 CHEMBL275902 Log EC50 2.512 nM
CC(C)c1c[nH]c(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O CHEMBL57740 Log Ki 2.512 nM
COc1cccc(Cl)c1OCCNCCOc1ccccc1OCc1ccccc1 CHEMBL1254828 pKi 2.512 nM
COc1cccc(C)c1OCCNCCOc1ccccc1OCc1ccccc1 CHEMBL1254829 pKi 2.512 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)NC(C)=C(C(C)=O)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL146815 Ki 2.57 nM
COc1ccccc1N1CCN(CCCNc2cc(-c3ccccc3)nn(C)c2=O)CC1 CHEMBL78785 Ki 2.59 nM
CC1=C(C(=O)NCCCN2CCC(c3ccccn3)CC2)[C@@H](c2ccc(F)c(F)c2)NC(=O)N1 CHEMBL327327 Ki 2.6 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3scc(-c4ccccc4)c3c2=O)CC1 CHEMBL268758 Ki 2.6 nM
CNC[C@H](O)c1ccc(O)c(O)c1 CHEMBL679 AC50 2.6 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3sc(C)c(-c4ccccc4)c3c2=O)CC1 CHEMBL13754 Ki 2.63 nM
COc1ccccc1N1CCN(CC2COCC(c3ccccc3)(c3ccccc3)O2)CC1 CHEMBL4466677 pKi 2.63 nM
Cc1ccc(-c2ccccc2NCC2=NCCN2)o1 CHEMBL152725 Log EC50 2.692 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(N3C(=O)c4cc(Cl)c(Cl)cc4C3=O)CC2)CC1 CHEMBL243692 Ki 2.7 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3ccccc3)CC2)CC1 CHEMBL234669 Ki 2.7 nM
C[C@H](Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)NCCOc1cc(Cl)ccc1OCC(F)(F)F CHEMBL3810346 IC50 2.7 nM
CC(Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)NCCOc1cc(Br)ccc1OCC(F)(F)F CHEMBL3808726 IC50 2.7 nM
CC(Cc1cc(C(N)=O)c2c(ccn2CCCO)c1)NCCOc1ccccc1OCc1ccccc1 CHEMBL3809093 IC50 2.7 nM
CC(Cc1cc(C(N)=O)c2c(ccn2CCCO)c1)NCCOc1ccc(F)cc1Br CHEMBL3808511 IC50 2.7 nM
Cc1ccc2c(N3CCN(CCc4cccc5c4OCc4c(C(N)=O)ncn4-5)CC3)cccc2n1 CHEMBL1241913 pKi 2.754 nM
COc1cccc(CCN2CCN(c3ccccc3OC(C)C)CC2)c1 CHEMBL3946843 pKi 2.754 nM
CNC[C@H](O)c1cccc(O)c1 CHEMBL1215 AC50 2.8 nM
CS(=O)(=O)c1ccc(Cl)cc1NCC1=NCCN1 CHEMBL70634 Log EC50 2.818 nM
COc1ccc2c(c1OCCNC[C@H]1COc3ccccc3O1)CCCC2 CHEMBL383938 Log Ki 2.818 nM
COc1cc2nc(N3CCN(C(=O)C4COc5ccccc5O4)[C@H]4CCCC[C@H]43)nc(N)c2cc1OC CHEMBL564481 pKi 2.818 nM
CC(C)Oc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 CHEMBL60583 pKi 2.818 nM
CC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(C#N)(c3ccccc3)CC2)=C(C)N1 CHEMBL347559 Ki 2.88 nM
COc1ccccc1N1CCN(C[C@H]2CO[C@@](CN3C(=O)CCC3=O)(c3ccccc3)O2)CC1 CHEMBL1242724 pKi 2.884 nM
COc1cc(Br)ccc1OCCNC(C)Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2 CHEMBL3809175 IC50 2.9 nM
COc1ccc(F)cc1OCCNC(C)Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2 CHEMBL3808896 IC50 2.9 nM
CCOc1ccccc1N1CCN(CCc2cccc(OC)c2)CC1 CHEMBL3947302 pKi 2.951 nM
COc1ccc(Cl)cc1N1CCN(CCCCNc2c(C(C)=O)c(C)nn(C)c2=O)CC1 CHEMBL420959 Ki 2.99 nM
CCOC(=O)C1CN(CCCCN2C(=O)c3cc(Cl)ccc3S2(=O)=O)CCC1c1ccccc1 CHEMBL1169493 Ki 3.0 nM
CCNC(=O)C1=C(COCCN)NC(CC)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL95253 Ki 3.0 nM
CC1=C(C(=O)NCCCN2CCC(c3ccccc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1C CHEMBL40464 Ki 3.0 nM
CC(C)Oc1ccccc1C1CCN([C@H]2CC[C@@H](NS(=O)(=O)c3ccc(F)c(F)c3)CC2)CC1 CHEMBL390184 Ki 3.0 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3ccc(Cl)cc3F)CC2)CC1 CHEMBL233582 Ki 3.0 nM
Cc1n[nH]cc1-c1cccc2c1CCC2c1ncc[nH]1 CHEMBL260720 EC50 3.0 nM
c1ccc([C@@H]2Cc3nccn3C2)c(-c2nccs2)c1 CHEMBL468710 EC50 3.0 nM
Fc1ccc(-c2ncco2)c(C2Cc3nccn3C2)c1 CHEMBL466634 EC50 3.0 nM
Fc1ccc(-c2ccn[nH]2)c(C2Cc3nccn3C2)c1 CHEMBL509350 EC50 3.0 nM
COc1ccccc1N1CCN(CCCCn2ccnc2SC)CC1 CHEMBL5182997 K 3.0 nM
c1ccc2c(SC3=NCCN3)c[nH]c2c1 CHEMBL2107015 AC50 3.0 nM
O=C1[C@H]2CCCC[C@H]2C(=O)N1CCCCN1CCN(c2nsc3ccccc23)CC1 CHEMBL1472975 AC50 3.0 nM
CC(=O)c1ccc2c(c1)N(CCCN(C)C)c1ccccc1S2 CHEMBL39560 AC50 3.0 nM
CN1CCN(CCCN2c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1 CHEMBL609109 AC50 3.0 nM
CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc21 CHEMBL285802 AC50 3.0 nM
COc1ccccc1N1CCN(CCn2c(C)nc3c4ccccc4nc-3c2O)CC1 CHEMBL99142 Log Ki 3.02 nM
COc1ccccc1N1CCN(CC2COC3(CCN(S(=O)(=O)c4cccc([N+](=O)[O-])c4)CC3)O2)CC1 CHEMBL3342871 pKi 3.02 nM
CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2ccc3c(c2)C(=O)N(c2ccc(C(C)(C)C)cc2)C3=O)CC1 CHEMBL68699 Ki 3.05 nM
COc1ccccc1N1CCN(CCn2c(=O)c3c(-c4ccccc4)csc3n(C)c2=O)CC1 CHEMBL14213 Ki 3.1 nM
Cc1ccc2c(c1)oc(=O)n2C1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 CHEMBL83041 Ki 3.1 nM
CNC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL284103 Ki 3.1 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3ccc(F)cc3F)CC2)CC1 CHEMBL403280 Ki 3.1 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(COCCN)NC(C)=C(C(N)=O)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL322405 Ki 3.15 nM
CC(C)OC(=O)c1ccccc1NCC1=NCCN1 CHEMBL319553 Log EC50 3.162 nM
Cc1ccoc1-c1ccccc1OCC1=NCCN1 CHEMBL143562 Log EC50 3.162 nM
c1ccc(-c2ccccc2OCC2=NCCN2)cc1 CHEMBL13789 Log EC50 3.162 nM
Cn1ccc(-c2ccccc2NCC2=NCCN2)n1 CHEMBL17856 Log EC50 3.162 nM
COc1cccc(OC)c1SCCNCCOc1ccccc1OCc1ccccc1 CHEMBL1254582 pKi 3.162 nM
CCOc1cccc(OCC)c1OCCNCCOc1ccccc1OCc1ccccc1 CHEMBL1254742 pKi 3.162 nM
COc1ccccc1OCCNCCOc1ccccc1OCc1ccccc1 CHEMBL1254915 pKi 3.162 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C#N)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL145332 Ki 3.2 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccccc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1 CHEMBL44042 Ki 3.2 nM
CC(Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)NCCOc1cc(Cl)ccc1OCC(F)(F)F CHEMBL3810005 IC50 3.2 nM
CC(Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)NCCOc1ccccc1OCC(F)(F)F CHEMBL3187195 IC50 3.2 nM
N#Cc1ccc2c(c1)N(CCCN1CCC(O)CC1)c1ccccc1S2 CHEMBL251940 AC50 3.2 nM
CN(C)S(=O)(=O)c1ccc2c(c1)N(CCCN1CCC(CCO)CC1)c1ccccc1S2 CHEMBL398880 AC50 3.2 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL3392246 Ki 3.3 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(COCCN=[N+]=[N-])N1 CHEMBL98063 Ki 3.3 nM
COc1ccc(S(=O)(=O)N[C@H]2CC[C@@H](N3CCC(c4cc(F)ccc4OC(C)C)CC3)CC2)cc1OC CHEMBL228659 Ki 3.3 nM
CN(C)CCCN1c2ccccc2Sc2ccc(C(F)(F)F)cc21 CHEMBL570 AC50 3.3 nM
CCCN(CCc1cccs1)[C@H]1CCc2c(O)cccc2C1 CHEMBL1303 AC50 3.3 nM
CC/C(=N\OC)c1ccccc1NCC1=NCCN1 CHEMBL156950 Log EC50 3.311 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccccc43)c2=O)CC1 CHEMBL220781 Log Ki 3.311 nM
CCSc1ccccc1NCC1=NCCN1 CHEMBL540035 Log EC50 3.388 nM
COc1cc2nc(N3CCN(C(=O)C4COc5ccccc5O4)[C@@H]4CCCC[C@@H]43)nc(N)c2cc1OC CHEMBL558890 pKi 3.388 nM
COc1ccccc1N1CCN(CCn2c(C)nc3c(sc4ccc(NC(=O)Cc5ccccc5)cc43)c2=O)CC1 CHEMBL3298021 pKi 3.388 nM
Cc1ccccc1C1(C#N)CCN(CCCNC(=O)C(c2cccc(F)c2)C(C)C)CC1 CHEMBL42514 Ki 3.4 nM
[2H]c1c([2H])c([2H])c([C@@H]2C[C@@H](N3CCN(C([2H])([2H])[2H])C(C)(C)C3)c3cc(Cl)ccc32)c([2H])c1[2H] CHEMBL5191141 Ki 3.4 nM
COc1ccc(Cl)cc1N1CCN(CCn2c(C)nc3c(sc4ccccc43)c2=O)CC1 CHEMBL222896 Log Ki 3.467 nM
COc1cc2nc(N3CCN(C(=O)c4ccc(Br)o4)[C@H]4CCCC[C@H]43)nc(N)c2cc1OC CHEMBL388884 Log Ki 3.467 nM
COc1cc2nc(N3CCN(C(=O)c4ccc(Br)o4)[C@H]4CCCC[C@@H]43)nc(N)c2cc1OC CHEMBL2261605 pKi 3.467 nM
COc1ccccc1N1CCN(CCc2ccc3c(c2)OCO3)CC1 CHEMBL2220978 pKi 3.467 nM
COC(=O)C1=C(C)N=C(C)N(CCC[C@H](C)CN2CCN(c3ccccc3C(N)=O)CC2)C1c1ccc(F)c(F)c1 CHEMBL358313 Ki 3.5 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3cnc(Cl)c(Br)c3)CC2)CC1 CHEMBL233790 Ki 3.5 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@@H](NS(=O)(=O)c3cccc(F)c3)CC2)CC1 CHEMBL232779 Ki 3.5 nM
CN(C)CC/C=C1/c2ccccc2Sc2ccc(Cl)cc21 CHEMBL908 AC50 3.5 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL2260362 pKi 3.548 nM
COc1ccccc1N1CCN(CCn2c(C)nc3c(sc4ccc(NC(=O)CCCC(=O)NCc5ccccc5)cc43)c2=O)CC1 CHEMBL3298022 pKi 3.548 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)N=C(C)/C(=C(/O)OC)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL41844 Ki 3.58 nM
COC(=O)C1=C(C)N=C(C)N(CCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL145278 Ki 3.6 nM
COc1ccccc1N1CCN(CCCNc2cc(O)nc(Nc3c(Cl)cccc3Cl)n2)CC1 CHEMBL179401 Ki 3.6 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3ccc(F)c(F)c3)CC2)CC1 CHEMBL256804 Ki 3.6 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)NC(C)=C(C(=O)OCCO)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL2260364 pKi 3.631 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)N=C(C)/C(=C(/O)OCCO)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL347501 Ki 3.66 nM
O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c1ccccc1 CHEMBL279516 Ki 3.7 nM
CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)n(C)n2)CC1 CHEMBL440499 Ki 3.7 nM
COc1ccccc1N1CCN(CC(O)COc2cccc3ccccc23)CC1 CHEMBL142635 Ki 3.7 nM
COc1cc(Br)ccc1OCCNC(C)Cc1cc(C(N)=O)c2c(ccn2CCCO)c1 CHEMBL3809794 IC50 3.7 nM
CCOC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL2260363 pKi 3.715 nM
CCO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL346649 Ki 3.72 nM
CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)on2)CC1 CHEMBL421324 Ki 3.8 nM
CCCC1=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCC)=C(CC)N1 CHEMBL316495 Ki 3.8 nM
CC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(CCCN)N1 CHEMBL95736 Ki 3.8 nM
O=S(=O)(N[C@H]1CC[C@H](N2CCC(c3ccccc3OC3CC3)CC2)CC1)c1cc(Cl)ccc1F CHEMBL228332 Ki 3.8 nM
COc1ccc(Cl)cc1S(=O)(=O)N[C@H]1CC[C@H](N2CCN(c3ccccc3OC(C)C)CC2)CC1 CHEMBL234607 Ki 3.8 nM
COc1ccc2c(c1OCCNC[C@H]1COc3ccccc3O1)NCC2 CHEMBL3216590 pKi 3.802 nM
COc1ccccc1N1CCN(CCn2c(C)nc3c(sc4ccc(NC(=O)c5ccccc5)cc43)c2=O)CC1 CHEMBL3298020 pKi 3.89 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(N3C(=O)c4ccc5ccc(F)cc5c4C3=O)CC2)CC1 CHEMBL243866 Ki 3.9 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)Cc3ccccc3)CC2)CC1 CHEMBL234650 Ki 3.9 nM
COc1ccc(CCNCC2CCc3ccccc3C2)cc1 CHEMBL282214 Log Ki 3.981 nM
CCCNC(=O)c1ccccc1NCc1c[nH]cn1 CHEMBL325745 Log EC50 3.981 nM
Cc1c[nH]c(=O)n(CC(C)(C)CN2CCN(c3ccccc3OCC(F)(F)F)CC2)c1=O CHEMBL417758 Log Ki 3.981 nM
C1=C(N2CCNCC2)c2nccn2Cc2ccccc21 CHEMBL1222552 pKi 3.981 nM
CC(C)C(=O)NCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O CHEMBL5275284 pKi 3.981 nM
O=S(=O)(N[C@H]1CC[C@@H](N2CCC(c3ccccc3OCC(F)(F)F)CC2)CC1)c1ccc2c(c1)OCCO2 CHEMBL439197 Ki 4.0 nM
CS(=O)(=O)Nc1cccc(-c2ccccc2[C@@H]2Cc3nccn3C2)c1 CHEMBL513871 EC50 4.0 nM
CC(Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)NCCOc1ccc(F)cc1OCC(F)(F)F CHEMBL3809630 IC50 4.0 nM
COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccc(C)cc1 CHEMBL42539 Ki 4.1 nM
COc1cc2nc(N3CCN(C(=O)c4ccccc4)[C@H]4CCCC[C@H]43)nc(N)c2cc1OC CHEMBL242934 Log Ki 4.169 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)NC(C)=C(C(C)=O)C2c2ccc3c(c2)OCO3)CC1 CHEMBL148552 pKi 4.169 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3scc(-c4cccc(C)c4)c3c2=O)CC1 CHEMBL13856 Ki 4.17 nM
COC(=O)C1(c2ccccc2)CCN(CCCCCN2C(C)=NC(C)=C(C(N)=O)C2c2ccc(F)cc2F)CC1 CHEMBL145353 Ki 4.2 nM
CCC1=C(C(N)=O)C(c2ccc(F)c(F)c2)N(C(=O)NCCC(C)N2CCC(C(=O)OC)(c3ccccc3)CC2)C(=O)N1 CHEMBL358590 Ki 4.2 nM
N#Cc1cc(F)ccc1C1CCN(CCCNC(=O)C2=C(C(F)(F)F)NC(=O)N[C@@H]2c2ccc(F)c(F)c2)CC1 CHEMBL94259 Ki 4.2 nM
CCOc1ccccc1N1CCN(CC(O)CNC(=O)c2ccc3c(c2)C(=O)N(c2cccc(F)c2)C3=O)CC1 CHEMBL419624 Ki 4.25 nM
COc1cc2nc(N3CCN(C(=O)c4cccs4)[C@H]4CCCC[C@H]43)nc(N)c2cc1OC CHEMBL242724 Log Ki 4.266 nM
COc1ccc([N+](=O)[O-])cc1S(=O)(=O)N[C@H]1CC[C@@H](N2CCN(c3ccccc3OC(C)C)CC2)CC1 CHEMBL429623 Ki 4.3 nM
COc1ccccc1N1CCN(CCCNc2cc(=O)n(C)c(=O)n2C)CC1 CHEMBL279229 AC50 4.3 nM
CC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(CCCCN)N1 CHEMBL95434 Ki 4.4 nM
COc1ccccc1OCCNC(C)Cc1cc(C(N)=O)c2c(ccn2CCCO)c1 CHEMBL3809319 IC50 4.4 nM
Cc1nc(-c2ccccc2NCC2=NCCN2)cs1 CHEMBL434074 Log EC50 4.467 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(Cl)cc1 CHEMBL146163 Ki 4.5 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC3(CC2)C(=O)Oc2ccccc23)C1c1ccc(F)c(F)c1 CHEMBL342111 Ki 4.5 nM
CCNC(=O)C1=C(CC)NC(COCCN)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL95290 Ki 4.5 nM
COc1ccc(Cl)cc1S(=O)(=O)N[C@H]1CC[C@H](N2CCC(c3ccccc3OC3CC3)CC2)CC1 CHEMBL228279 Ki 4.5 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@@H](NS(=O)(=O)c3ccc(Cl)cc3Cl)CC2)CC1 CHEMBL391035 Ki 4.5 nM
CC(=O)c1ccc2c(c1)N(CCCN1CCN(CCO)CC1)c1ccccc1S2 CHEMBL1085 AC50 4.5 nM
CSc1ccccc1NCC1=NCCN1 CHEMBL540542 Log EC50 4.571 nM
c1ccc(-c2cnccn2)c(NCC2=NCCN2)c1 CHEMBL349082 Log EC50 4.571 nM
COc1ccc2ccccc2c1OCCNC[C@@H]1COc2ccccc2O1 CHEMBL439346 Log Ki 4.571 nM
COc1ccccc1N1CCN(CC2COC3(CCN(S(=O)(=O)c4ccc(C)cc4)CC3)O2)CC1 CHEMBL3342867 pKi 4.571 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(c3cc(C)cc(C)c3)(c3cc(C)cc(C)c3)CC2)C1c1ccc(F)c(F)c1 CHEMBL145719 Ki 4.6 nM
COc1cc(F)ccc1OCCNC(C)Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2 CHEMBL3809600 IC50 4.6 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@H]2CC[C@@H](N3CCC(c4ccccn4)CC3)C2)C(=O)N1 CHEMBL57691 Ki 4.7 nM
COc1cc2nc(N3CCN(C(=S)Nc4ccc(-c5c6ccc(=O)cc-6oc6cc(O)ccc56)c(C(=O)O)c4)CC3)nc(N)c2cc1OC CHEMBL3582271 Ki 4.7 nM
COc1ccccc1N1CCN(CCn2nc(-c3ccccc3)c(C(C)=O)c(N)c2=O)CC1 CHEMBL301726 Ki 4.75 nM
CCNC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL357681 pKi 4.786 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)NC(C)=C(C(=O)OCCC#N)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL2260361 pKi 4.786 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)N=C(C)/C(=C(/O)OCCC#N)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL151825 Ki 4.79 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@H]2CC[C@H](N3CCN(c4ccccc4C#N)CC3)C2)C(=O)N1 CHEMBL278716 Ki 4.8 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(COCCCN)N1 CHEMBL95578 Ki 4.8 nM
O=S(=O)(N[C@H]1CC[C@H](N2CCC(c3ccccc3OCC(F)(F)F)CC2)CC1)c1cc(Cl)ccc1F CHEMBL228494 Ki 4.8 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@@H](NS(=O)(=O)c3ccc(S(C)(=O)=O)cc3)CC2)CC1 CHEMBL236617 Ki 4.8 nM
COc1ccccc1OCCNC(C)Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2 CHEMBL3808408 IC50 4.8 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3cccc(C(F)(F)F)c3)CC2)C1c1ccc(F)c(F)c1 CHEMBL145525 Ki 4.9 nM
COc1ccncc1S(=O)(=O)N[C@H]1CC[C@@H](N2CCN(c3ccccc3OC(C)C)CC2)CC1 CHEMBL232607 Ki 4.9 nM
COc1cccc(C2CCC(N3CCN(c4ccccc4OC)CC3)CC2)c1 CHEMBL2112779 Ki 4.98 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL143940 Ki 5.0 nM
C[C@@]1(O)C(=O)N(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)C(=O)N[C@@H]1O CHEMBL360688 Ki 5.0 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@@H](NS(=O)(=O)c3cccnc3)CC2)CC1 CHEMBL234854 Ki 5.0 nM
Fc1ccn(Cc2c(F)ccc3c2CC[C@H]3c2ncc[nH]2)n1 CHEMBL474796 Ki 5.0 nM
c1ccc(-n2cccn2)c([C@@H]2Cc3nccn3C2)c1 CHEMBL448908 EC50 5.0 nM
Fc1ccc(-n2cccn2)c(C2Cc3nccn3C2)c1 CHEMBL510023 EC50 5.0 nM
COc1ccccc1N1CCN(CCCCNC(=O)Nc2cccc(Cl)c2)CC1 CHEMBL3758991 Ki 5.0 nM
c1ccc(-c2ccns2)c(OCC2=NCCN2)c1 CHEMBL142387 Log EC50 5.012 nM
c1ccc(-c2cc[nH]n2)c(OCC2=NCCN2)c1 CHEMBL344551 Log EC50 5.012 nM
CC(C)Sc1ccccc1NCC1=NCCN1 CHEMBL553276 Log EC50 5.012 nM
CSc1ccccc1NCC1=NCCN1 CHEMBL117248 Log EC50 5.012 nM
C[C@]1(O)C(=O)N(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)C(=O)N[C@H]1O CHEMBL56375 Log Ki 5.012 nM
Oc1cccc(O)c1OCCNCCOc1ccccc1OCc1ccccc1 CHEMBL1255085 pKi 5.012 nM
CC(C)Oc1ccccc1N1CCN(CCc2ccccc2)CC1 CHEMBL3967641 pKi 5.012 nM
COC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C(c2ccc(C)cc2)c2ccc(C)cc2)CC1 CHEMBL41677 Ki 5.1 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(CCCCOC)N1 CHEMBL99864 Ki 5.1 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3cccc(Cl)c3)CC2)CC1 CHEMBL257077 Ki 5.1 nM
COCC1=C(C(=O)OC)C(c2ccc(F)c(F)c2)N(C(=O)NCCCN2CCC(C#N)(c3ccccc3F)CC2)C(=O)N1 CHEMBL145134 Ki 5.2 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)CCCCc5ccccc5)cc43)c2=O)CC1 CHEMBL3298748 pKi 5.248 nM
COc1ccccc1N1CCN(CC2COC3(CCN(S(=O)(=O)c4ccc([N+](=O)[O-])cc4)CC3)O2)CC1 CHEMBL3342870 pKi 5.248 nM
COc1cccc(N(NC2=NCCO2)c2ccc(C)cc2)c1 CHEMBL194323 Ki 5.25 nM
Cc1ccc(N(NC2=NCCO2)c2cccc(O)c2)cc1 CHEMBL370818 Ki 5.25 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3c(F)cccc3F)CC2)CC1 CHEMBL270589 Ki 5.3 nM
O=S(=O)(N[C@H]1CC[C@@H](N2CCC(c3ccccc3OCC(F)(F)F)CC2)CC1)c1ccc(OC(F)F)cc1 CHEMBL387832 Ki 5.4 nM
CC(CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1 CHEMBL926 AC50 5.4 nM
COCCOC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)NC(C)=C(C(N)=O)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL357061 Ki 5.41 nM
COc1ccccc1N1CCN(CCCCN(C)C(=O)c2cnc(SC)n2C)CC1 CHEMBL5189175 K 5.45 nM
COc1cc2nc(N3CCN(C(=O)c4ccco4)[C@H]4CCCC[C@H]43)nc(N)c2cc1OC CHEMBL423294 pKi 5.495 nM
COc1cc2nc(N3CCN(C(=O)OCc4ccccc4)[C@H]4CCCC[C@H]43)nc(N)c2cc1OC CHEMBL4125981 pKi 5.495 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@@H](NS(=O)(=O)c3ccc(F)cc3)CC2)CC1 CHEMBL234874 Ki 5.6 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@@H](NS(=O)(=O)c3ccccc3F)CC2)CC1 CHEMBL399195 Ki 5.6 nM
CS(=O)(=O)Nc1c(O)ccc2c1CCC[C@H]2C1=NCCN1 CHEMBL336161 Log EC50 5.623 nM
COc1ccc(-c2ccccc2)cc1OCCNC[C@H]1COc2ccccc2O1 CHEMBL214694 Log Ki 5.623 nM
COc1cccc(OC)c1OCCNC[C@@H]1COc2cccc(Cl)c2O1 CHEMBL2153556 pKi 5.623 nM
Cc1ccc(C(O)(C(=O)NCCCN2CCC(C#N)(c3ccccc3)CC2)c2ccc(C)cc2)cc1 CHEMBL61643 Ki 5.7 nM
CCCCCC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)[C@@H]2CCCC[C@@H]21 CHEMBL4127078 pKi 5.754 nM
N#CC1(c2ccccc2)CCN(CCCNC(=O)N2C(=O)NC3=C(C(=O)OC3)C2c2ccc(F)c(F)c2)CC1 CHEMBL298579 Ki 5.8 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3cccnc3)CC2)CC1 CHEMBL391016 Ki 5.8 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL284470 Log Ki 5.888 nM
O=S(=O)(N[C@H]1CC[C@@H](N2CCC(c3ccccc3OCC(F)(F)F)CC2)CC1)c1cc(Cl)ccc1F CHEMBL228445 Ki 5.9 nM
Cn1nc(Cl)c2cn3nc(NCCN4CCN(c5ccccc5Cl)CC4)ccc3c2c1=O CHEMBL49851 Ki 5.93 nM
CC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(C(=O)Oc3ccccc3)(c3ccccc3)CC2)=C(C)N1 CHEMBL358406 Ki 5.98 nM
COc1ccc(F)cc1S(=O)(=O)N[C@H]1CC[C@@H](N2CCN(c3ccccc3OC(C)C)CC2)CC1 CHEMBL233814 Ki 6.0 nM
COc1ccccc1N1CCN(CCCCNc2ccc3ccccc3n2)CC1 CHEMBL271989 Ki 6.0 nM
COc1ccccc1N1CCN(CCCCNc2nccc3ccccc23)CC1 CHEMBL1223748 Ki 6.0 nM
O=C1Cc2cc(CCN3CCN(c4nsc5ccccc45)CC3)c(Cl)cc2N1 CHEMBL708 Ki 6.0 nM
c1ccc2c(c1)CCCC2C1=NCCN1 CHEMBL1266 AC50 6.1 nM
CCOC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)NC(C)=C(C(=O)NC)C2c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL355910 Ki 6.12 nM
CNC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL358253 pKi 6.166 nM
COc1ccc(Cl)cc1S(=O)(=O)N[C@H]1CC[C@@H](N2CCC(c3ccccc3OCC(F)(F)F)CC2)CC1 CHEMBL442059 Ki 6.2 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3c(Cl)cccc3Cl)CC2)CC1 CHEMBL256597 Ki 6.2 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@@H](NS(=O)(=O)c3ccccc3[N+](=O)[O-])CC2)CC1 CHEMBL232592 Ki 6.3 nM
Cn1ccnc1-c1ccccc1NCC1=NCCN1 CHEMBL18256 Log EC50 6.31 nM
CC(C)n1ncnc1-c1ccccc1NCC1=NCCN1 CHEMBL17151 Log EC50 6.31 nM
Oc1ccc2cccc(NCC3=NCCN3)c2c1 CHEMBL114669 Log EC50 6.31 nM
c1ccc(-c2ccno2)c(OCC2=NCCN2)c1 CHEMBL327005 Log EC50 6.31 nM
COc1ccc(C2(c3ccccc3)CCN(CCCNC(=O)C3=C(COCCN)NC(C)=C(C(N)=O)C3c3ccc([N+](=O)[O-])cc3)CC2)cc1 CHEMBL330401 Ki 6.31 nM
CN(C)c1c[nH]c(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O CHEMBL291951 Log Ki 6.31 nM
Clc1cccc(Cl)c1OCCNCCOc1ccccc1OCc1ccccc1 CHEMBL1255002 pKi 6.31 nM
CCCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2cnccc2c1=O CHEMBL2146806 pKi 6.31 nM
COCCNC(=O)CCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O CHEMBL5272034 pKi 6.31 nM
Cc1ccccc1C1(C#N)CCN(CCCNC(=O)C(c2ccc(Cl)cc2)C(C)C)CC1 CHEMBL289339 Ki 6.4 nM
COc1ccccc1N1CCN(CC2COC3(CCN(c4ccccc4)CC3)O2)CC1 CHEMBL3342857 pKi 6.457 nM
COc1ccccc1N1CCN(CC2COC3(CCN(S(=O)(=O)c4ccc(Cl)cc4)CC3)O2)CC1 CHEMBL3342868 pKi 6.457 nM
COc1ccccc1CCN1CCC2(CC1)CC(=O)c1ccc(NS(C)(=O)=O)cc1O2 CHEMBL431631 Ki 6.5 nM
CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3c(Cl)cc(Cl)cc3Cl)CC2)CC1 CHEMBL256040 Ki 6.5 nM
CCOc1ccccc1OCCNCC1COC(c2ccccc2)(c2ccccc2)O1 CHEMBL1078953 pKi 6.607 nM
COc1ccccc1N1CCN(C[C@H]2CO[C@@](CN3C(=O)CCCC3=O)(c3ccccc3)O2)CC1 CHEMBL1242818 pKi 6.607 nM
COc1cc2nc(N3CCN(C(=O)C(C)(C)C)[C@H]4CCCC[C@H]43)nc(N)c2cc1OC CHEMBL4128460 pKi 6.607 nM
NC(=O)c1ccccc1OCCCN1CCN(c2cccc3c2ccn3S(=O)(=O)c2ccccc2)CC1 CHEMBL3409256 Kb 6.7 nM
COc1ccccc1N1CCN(CCCCn2ncc(=O)n(C)c2=O)CC1 CHEMBL2413154 Ki 6.75 nM
COc1cccc(N2CCN(CCCCn3ncc(=O)n(C)c3=O)CC2)c1 CHEMBL426317 Ki 6.75 nM
c1ccc(-c2ccccc2NCC2=NCCN2)nc1 CHEMBL154298 Log EC50 6.761 nM
COc1ccccc1N1CCN(CC2COC3(CCN(Cc4ccccc4)CC3)O2)CC1 CHEMBL3342853 pKi 6.761 nM
COc1cccc(OC)c1OCCNCC1Oc2ccccc2CC1c1ccccc1 CHEMBL318257 Log Ki 6.78 nM
COC(=O)C1=C(C)N=C(C)N(Cc2cccc(CN3CCC(C(=O)OC)(c4ccccc4)CC3)c2)C1c1ccc(F)c(F)c1 CHEMBL144731 Ki 6.8 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(c3ccc(Cl)cc3)(c3ccc(Cl)cc3)CC2)C1c1ccc(F)c(F)c1 CHEMBL356571 Ki 6.9 nM
COC(CNC(=O)c1ccc2c(c1)C(=O)N(c1cccc(F)c1)C2=O)CN1CCN(c2ccccc2OC(C)C)CC1 CHEMBL69245 Ki 6.9 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)CCCN(C)Cc5ccccc5)cc43)c2=O)CC1 CHEMBL3298018 pKi 6.918 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1C CHEMBL43594 Ki 7.0 nM
O=S(=O)(N[C@H]1CC[C@@H](N2CCC(c3ccccc3OCC(F)(F)F)CC2)CC1)c1cccc(OC(F)F)c1 CHEMBL228496 Ki 7.0 nM
Cc1cccc2c(NCCNc3ccnc4c(C)cccc34)ccnc12 CHEMBL3343979 Ki 7.0 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(OC)cc1 CHEMBL315538 Log Ki 7.079 nM
Cc1ccc(CCn2c3c(c4cc(C)ccc42)CN(C)CC3)cc1 CHEMBL605081 pKi 7.079 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(OC)cc1 CHEMBL2260150 pKi 7.079 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)CCCc5ccccc5)cc43)c2=O)CC1 CHEMBL3298747 pKi 7.079 nM
COc1cc2nc(N3CCC[C@H](NC4=CC(=O)c5ccccc5C4=O)C3)nc(N)c2cc1OC CHEMBL4163587 pKi 7.079 nM
CC(Oc1c(Cl)cccc1Cl)C1=NCCN1 CHEMBL17860 AC50 7.1 nM
COc1ccccc1N1CCN(CCCNC(=O)Nc2ccccc2-c2ccccc2)CC1 CHEMBL5400232 Ki 7.1 nM
COc1cccc(OC)c1OCCNCC1=Cc2ccccc2OC1c1ccccc1 CHEMBL329035 Log Ki 7.14 nM
CN1CCC[C@@H]1CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1 CHEMBL1626 AC50 7.2 nM
COc1ccccc1OCCNCCC1COC(c2ccccc2)(c2ccccc2)O1 CHEMBL4458714 pKi 7.244 nM
Cc1ccc(C(C(=O)NCCCN2CCC(C#N)(c3ccccc3)CC2)c2ccc(C)cc2)cc1 CHEMBL44124 Ki 7.3 nM
Cc1ccc(C(C(=O)NCCCN2CCC(C#N)(c3ccccc3C)CC2)C(C)C)cc1 CHEMBL297667 Ki 7.4 nM
COc1cccc(OC)c1OCCNCC1C(=O)c2ccccc2SC1c1ccccc1 CHEMBL98413 Log Ki 7.42 nM
COc1ccccc1C1(C#N)CCN(CCCNC(=O)C(c2ccc(C)cc2)c2ccc(C)cc2)CC1 CHEMBL42220 Ki 7.5 nM
COCC1=C(C(=O)OC)C(c2ccc(F)c(F)c2)N(C(=O)N2CCC(N3CCC(C(=O)OC)(c4ccccc4)CC3)CC2)C(=O)N1 CHEMBL341838 Ki 7.5 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@H](NS(=O)(=O)c3ccc(S(C)(=O)=O)cc3)CC2)CC1 CHEMBL236618 Ki 7.5 nM
COc1cc(C)ccc1OCCNC(C)Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2 CHEMBL3810220 IC50 7.6 nM
CCOC(=O)C1(c2ccccc2)CCN(CCCNC(=O)C2=C(C)NC(C)=C(C(N)=O)C2c2ccc3c(c2)OCO3)CC1 CHEMBL149263 Ki 7.7 nM
CC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(O)(c3ccccc3)CC2)=C(C)N1 CHEMBL151045 Ki 7.7 nM
CSc1c(F)cccc1NCC1=NCCN1 CHEMBL70692 Log EC50 7.762 nM
CSc1cc(F)ccc1NCC1=NCCN1 CHEMBL306792 Log EC50 7.762 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC3(CC2)OC(=O)c2ccccc23)C1c1ccc(F)c(F)c1 CHEMBL145571 Ki 7.9 nM
O=C(CCCN1CCC2(CC1)C(=O)NCN2c1ccccc1)c1ccc(F)cc1 CHEMBL267930 Ki 7.9 nM
COc1ccccc1N1CCN(CC2CO[C@H](c3cccc4ccccc34)O2)CC1 CHEMBL2234446 Ki 7.94 nM
CCCNC(=O)c1ccccc1NCC1=NCCN1 CHEMBL318544 Log EC50 7.943 nM
CC(C)(C)OC(=O)c1ccccc1NCC1=NCCN1 CHEMBL98243 Log EC50 7.943 nM
c1ccc(-c2ccccc2NCC2=NCCN2)cc1 CHEMBL337862 Log EC50 7.943 nM
O=c1[nH]cc(CO)c(=O)n1CCCN1CCN(c2ccc(F)cc2OCC(F)(F)F)CC1 CHEMBL55645 Log Ki 7.943 nM
COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1ccccc1[N+](=O)[O-] CHEMBL200136 Log Ki 7.943 nM
Cc1cccc(C)c1OCCNCCOc1ccccc1OCc1ccccc1 CHEMBL1255003 pKi 7.943 nM
COc1ccccc1N1CCN(CC2COC3(CCN(S(=O)(=O)c4ccccc4)CC3)O2)CC1 CHEMBL3342866 pKi 7.943 nM
COc1ccccc1N1CCN(CC2COC3(CCN(S(=O)(=O)c4cccs4)CC3)O2)CC1 CHEMBL3342872 pKi 7.943 nM
c1cnc2c(N3CCN(CCc4ccc(OCCCN5CCCCCC5)cc4)CC3)cccc2c1 CHEMBL3947980 pKi 7.943 nM
COCCC(=O)NCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O CHEMBL5286701 pKi 7.943 nM
Cn1cnc(S(=O)(=O)Nc2ccc3c(c2)C(=O)CC2(CCN(CCc4cccc5ccccc45)CC2)O3)c1 CHEMBL101579 Ki 8.0 nM
Cc1[nH]c2ccccc2c1CCN1CCC2(CC1)CC(=O)c1ccc(NS(C)(=O)=O)cc1O2 CHEMBL98430 Ki 8.0 nM
COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(C)cc1 CHEMBL359173 Ki 8.0 nM
CC(C)Oc1ccccc1N1CCN(C[C@H](O)CNC(=O)c2ccc3c(c2)C(=O)N(c2cccc(F)c2)C3=O)CC1 CHEMBL71473 Ki 8.0 nM
COc1cc(F)ccc1OCCNC(C)Cc1cc(C(N)=O)c2c(ccn2CCCO)c1 CHEMBL3809676 IC50 8.0 nM
COc1cccc(OC)c1OCCNCC1C(=O)c2ccccc2CC1c1ccccc1 CHEMBL330599 Log Ki 8.06 nM
COc1cc(Cl)ccc1OCCNC(C)Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2 CHEMBL3808417 IC50 8.1 nM
COc1cc2nc(N3CCN(C(=O)CC(=O)c4ccccc4)CC3)nc(N)c2cc1OC CHEMBL434228 Ki 8.17 nM
COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC CHEMBL709 Ki 8.2 nM
COc1ccccc1N1CCN(CCCNC(=O)Nc2ccccc2-c2ccc(-c3ccccc3)cc2)CC1 CHEMBL5394229 Ki 8.2 nM
COCC1=C(C(=O)OC)[C@H](c2ccc(F)c(F)c2)N(C(=O)N[C@H]2CC[C@H](N3CCC(c4ccccn4)CC3)C2)C(=O)N1 CHEMBL56248 Ki 8.3 nM
COc1ccc(Cl)cc1N1CCN(CCn2c(=O)[nH]c3c([nH]c4ccccc43)c2=O)CC1 CHEMBL386005 Log Ki 8.318 nM
CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)no2)CC1 CHEMBL81093 Ki 8.4 nM
COc1ccccc1N1CCN(CCCn2c(=O)[nH]c3scc(-c4ccccc4)c3c2=O)CC1 CHEMBL14199 Ki 8.49 nM
COc1ccc(S(=O)(=O)N[C@H]2CC[C@@H](N3CCC(c4ccccc4OCCF)CC3)CC2)cc1OC CHEMBL538397 Ki 8.5 nM
COc1ccccc1N1CCN(CC2COC3(CCSCC3)O2)CC1 CHEMBL3342852 pKi 8.511 nM
CC(Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)NCCOc1ccccc1OCc1ccccc1 CHEMBL3808632 IC50 8.6 nM
CC(C)Oc1ccccc1N1CCN(CCNC(=O)CN2CCCCC2=O)CC1 CHEMBL275469 Ki 8.7 nM
COc1ccc(OC)c(S(=O)(=O)N[C@H]2CC[C@@H](N3CCN(c4ccccc4OC(C)C)CC3)CC2)c1 CHEMBL236832 Ki 8.7 nM
COc1cccc(OC)c1OCCNC[C@@H]1C(=O)c2ccccc2C[C@H]1c1ccccc1 CHEMBL2234444 Ki 8.7 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL91956 Log Ki 8.71 nM
CC1=C(C(N)=O)C(c2ccc3c(c2)OCO3)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(C)N1 CHEMBL312871 Log Ki 8.71 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL2260371 pKi 8.71 nM
Cc1ccc(C(C(=O)NCCCN2CCC(c3ccccc3)CC2)c2ccc(C)cc2)cc1 CHEMBL295304 Ki 8.8 nM
O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1 CHEMBL1112 Ki 8.9 nM
COc1ccc(-c2ccccc2)c(CNC(=O)NCCCN2CCN(c3ccccc3OC)CC2)c1 CHEMBL5403204 Ki 8.9 nM
CC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc2c(c1)OCO2 CHEMBL88388 Log Ki 8.913 nM
COc1ccccc1N1CCN(CC2COC3(CCN(S(=O)(=O)c4ccc(OC(F)(F)F)cc4)CC3)O2)CC1 CHEMBL3342869 pKi 8.913 nM
Cc1nc2ccccn2c(=O)c1CCN1CCN(c2cccc3sccc23)CC1 CHEMBL4094825 IC50 8.99 nM
CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)nn2C)CC1 CHEMBL76867 Ki 9.0 nM
CCS(=O)(=O)Nc1cccc(Cc2c[nH]cn2)c1 CHEMBL326702 EC50 9.0 nM
Cn1cc(-c2ccccc2[C@@H]2Cc3nccn3C2)cn1 CHEMBL508084 EC50 9.0 nM
Fc1ccccc1N1CCN(CCCCNc2cc(-c3ccccc3)ccn2)CC1 CHEMBL1223802 Ki 9.0 nM
CC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(C(=O)OCCO)(c3ccccc3)CC2)=C(C)N1 CHEMBL356623 Ki 9.05 nM
O=C1OCC2=C1C(c1ccc(F)c(F)c1)N(C(=O)NCCCN1CCC(c3ccccc3)(c3ccccc3)CC1)C(=O)N2 CHEMBL50490 Ki 9.1 nM
COc1ccc2ccoc2c1OCCNC[C@@H]1COc2ccccc2O1 CHEMBL2419770 pKi 9.12 nM
COc1cc2nc(N3CCN(C(C)=O)[C@@H]4CCCC[C@@H]43)nc(N)c2cc1OC CHEMBL4129461 pKi 9.12 nM
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1 CHEMBL25236 Ki 9.15 nM
COc1cccc(OC)c1OCCNCC1C(=O)c2ccccc2OC1c1ccccc1 CHEMBL99489 Log Ki 9.22 nM
CS(=O)(=O)Nc1c(O)ccc2c1CCCC2C1=NCCN1 CHEMBL109783 EC50 9.3 nM
N=C(N)NC(=O)Cc1c(Cl)cccc1Cl CHEMBL862 AC50 9.3 nM
COc1cccc(-c2ccccc2)c1OCCNC[C@@H]1COc2ccccc2O1 CHEMBL214952 Log Ki 9.333 nM
Nc1ccc(C(=O)NCCN2CCC(c3cccc4[nH]ccc34)CC2)cc1 CHEMBL179721 Ki 9.5 nM
CC(C)Oc1ccccc1N1CCN([C@H]2CC[C@@H](NS(=O)(=O)c3ccccc3C#N)CC2)CC1 CHEMBL234679 Ki 9.6 nM
Cc1ccc(C2(c3ccc(C)cc3)CC(=O)N(CC(O)CN3CCC(C#N)(c4ccccc4C)CC3)C2=O)cc1 CHEMBL62249 Ki 9.7 nM
COc1cccc(OC)c1CCCNCCOc1ccccc1OCc1ccccc1 CHEMBL1254659 pKi 9.772 nM
COc1ccccc1N1CCN(CCCCN2C(=O)CC3(CCc4ccccc43)CC2=O)CC1 CHEMBL1796050 pKi 9.772 nM
COc1ccccc1N1CCN(CC2COC3(CCS(=O)(=O)CC3)O2)CC1 CHEMBL3342855 pKi 9.772 nM
Clc1ccc2nsnc2c1NC1=NCCN1 CHEMBL1079 AC50 9.8 nM
CNC(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL1627 Ki 9.9 nM
COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12 CHEMBL723 AC50 9.9 nM