c1ccc2c(c1)C[C@]1(c3c[nH]cn3)C[C@H]21 CHEMBL1256414 pKi 0.1096 nM
CC[C@H]1[C@@H]2c3ccccc3C[C@]12c1c[nH]cn1 CHEMBL1255723 pKi 0.182 nM
C[C@H]1[C@@H]2c3ccccc3C[C@]12c1c[nH]cn1 CHEMBL1256378 pKi 0.2042 nM
CCN(CC)C(=O)N[C@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1 CHEMBL157138 Ki 0.237 nM
CCC[C@H]1[C@@H]2c3ccccc3C[C@]12c1c[nH]cn1 CHEMBL1255724 pKi 0.3467 nM
O=C1O[C@H]([C@@H](O)CO)C(O)=C1O CHEMBL196 EC50 0.5 nM
CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(C[N+]3(C)CCCC3)CS[C@H]12)c1csc(N)n1 CHEMBL186 AC50 0.5 nM
C[C@H]1c2ccccc2[C@H]2C[C@]21c1c[nH]cn1 CHEMBL1256609 pKi 0.6918 nM
NC(=O)C1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1 CHEMBL1909072 Ki 0.786 nM
C[C@]12C[C@@]1(c1c[nH]cn1)Cc1ccccc12 CHEMBL1255771 pKi 0.912 nM
Cc1nc2ccc(Cl)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1 CHEMBL351483 pIC50 0.955 nM
CC1(C)[C@@H]2c3ccccc3C[C@@]21c1c[nH]cn1 CHEMBL1255770 pKi 1.148 nM
COC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL15245 Ki 1.16 nM
Cc1nc2c(Cl)cc(Cl)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1 CHEMBL163247 pIC50 1.259 nM
Cc1nc2ccc(Br)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1 CHEMBL165350 pIC50 1.349 nM
CC(C)[C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C=C4c5cccc6[nH]cc(c56)C[C@H]4N(C)C3)(C(C)C)C(=O)N12 CHEMBL1385840 Ki 1.396 nM
COc1cc2c(cc1OC)C1=NO[C@@H](CN3CCN(C/C(C)=C/c4ccc(F)cc4)CC3)[C@@H]1CO2 CHEMBL318235 Kb 1.4 nM
CN1CC2c3ccccc3Oc3ccc(Cl)cc3C2C1 CHEMBL3187365 AC50 1.4 nM
Cc1nc2cccc(C)n2c(=O)c1CCN1CCc2oc3ccccc3c2C1 CHEMBL163190 pIC50 1.479 nM
Cc1ccc2nc(C)c(CCN3CCc4oc5ccccc5c4C3)c(=O)n2c1 CHEMBL162370 pIC50 1.549 nM
COC1(C2=NCCN2)COc2ccccc2O1 CHEMBL10332 pKi 1.622 nM
CC[C@H]1c2ccccc2[C@H]2C[C@]21c1c[nH]cn1 CHEMBL1256610 pKi 1.622 nM
Cc1nc2c(O)cccn2c(=O)c1CCN1CCc2oc3ccccc3c2C1 CHEMBL162826 pIC50 1.738 nM
CN1C[C@H](C(=O)N[C@]2(C)O[C@@]3(O)[C@@H]4CCCN4C(=O)[C@H](Cc4ccccc4)N3C2=O)C=C2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL442 Ki 1.755 nM
CN1C[C@H](C(=O)N[C@]2(C)O[C@@]3(O)[C@@H]4CCCN4C(=O)[C@H](Cc4ccccc4)N3C2=O)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL1732 Ki 1.766 nM
c1ccc2c(c1)[C@H]1C[C@@]1(c1c[nH]cn1)C21CC1 CHEMBL1255617 pKi 1.905 nM
Cc1nc2c(Cl)cc(C(F)(F)F)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1 CHEMBL162147 pIC50 1.95 nM
C(=C/c1ccccc1)\CN1CCN(CC2ON=C3c4ccccc4OCC32)CC1 CHEMBL90943 Ki 2.0 nM
COc1cccn2c(=O)c(CCN3CCc4oc5ccccc5c4C3)c(C)nc12 CHEMBL162490 pIC50 2.042 nM
Cc1nc2ccc(I)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1 CHEMBL162682 pIC50 2.089 nM
Cc1nc2c(C)cccn2c(=O)c1CCN1CCc2oc3ccccc3c2C1 CHEMBL351200 pIC50 2.138 nM
c1ccc2c(c1)CCCC2NC1=NCCO1 CHEMBL75030 Log Ki 2.138 nM
CCC1(c2c[nH]cn2)Cc2ccccc2C1 CHEMBL353972 pKi 2.239 nM
CCC[C@H]1c2ccccc2[C@H]2C[C@]21c1c[nH]cn1 CHEMBL1255616 pKi 2.291 nM
Cc1ccn2c(=O)c(CCN3CCc4oc5ccccc5c4C3)c(C)nc2c1 CHEMBL165796 pIC50 2.57 nM
Cc1nc2ccccn2c(=O)c1CCN1CCc2oc3ccccc3c2C1 CHEMBL162501 pIC50 2.57 nM
Cc1cc(C)n2c(=O)c(CCN3CCc4oc5ccccc5c4C3)c(C)nc2c1 CHEMBL162232 pIC50 2.63 nM
CO[C@H]1c2ccccc2[C@H]2C[C@]21c1c[nH]cn1 CHEMBL1256503 pKi 2.818 nM
COc1cc2c(cc1OC)C1=NO[C@@H](CN3CCN(C/C(C)=C/c4ccccc4)CC3)[C@@H]1CO2 CHEMBL91157 Ki 3.0 nM
C=Cc1sc2ccc(Cl)c3c2c1CN(C)CC3 CHEMBL25467 Ki 3.4 nM
CC(C)[C@@]1(NC(=O)[C@@H]2C[C@@H]3c4cccc5[nH]cc(c45)C[C@H]3N(C)C2)O[C@@]2(O)[C@@H]3CCCN3C(=O)[C@H](Cc3ccccc3)N2C1=O CHEMBL1255837 Ki 3.606 nM
CN(C)CCC=C1c2ccccc2CCc2ccccc21 CHEMBL629 Ki 3.687 nM
CNc1cc[n+](CCNC(=O)c2ccn3c(-c4ccccc4OC)cnc3c2)cc1 CHEMBL5404808 IC50 4.0 nM
O=c1c(CCN2CCc3oc4ccccc4c3C2)c(Cc2ccccc2)nc2ccccn12 CHEMBL162436 pIC50 4.169 nM
Cc1nc2ccccn2c(=O)c1CCN1CCc2oc3c(Cl)cccc3c2C1 CHEMBL164612 pIC50 4.365 nM
COc1cc2c(cc1OC)C1=NOC(CN3CCN(C/C(C)=C/c4ccccc4)CC3)C1CN2 CHEMBL390718 Ki 4.5 nM
COC(=O)[C@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@H]2CC[C@@H]1O CHEMBL10347 Ki 4.7 nM
CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1 CHEMBL728 Ki 4.741 nM
COc1ccccc1-n1cnc2cc(NC(=O)CCc3ccccn3)ccc21 CHEMBL5406707 IC50 5.0 nM
c1ccc(Oc2ncccc2-c2noc(CN3CCCN(CC4COc5ccccc5O4)CC3)n2)cc1 CHEMBL491420 Ki 5.2 nM
CCN(CC)C(=O)N[C@H]1C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1 CHEMBL73151 AC50 5.5 nM
CCC[C@H]1CCCC[C@@H]1NC1=NCCO1 CHEMBL297752 Log Ki 5.888 nM
CCC[C@H]1CCCCC1NC1=NCCO1 CHEMBL310335 Log Ki 5.888 nM
Clc1cccc(Cl)c1NC1=NCCN1 CHEMBL134 Log Ki 6.166 nM
CCCO[C@H]1c2ccccc2[C@H]2C[C@]21c1c[nH]cn1 CHEMBL1256566 pKi 6.457 nM
CCC1(c2c[nH]cn2)Cc2ccc(F)cc2C1 CHEMBL1255582 pKi 6.761 nM
c1ccc(CC[C@H]2CCCC[C@@H]2NC2=NCCO2)cc1 CHEMBL47313 Log Ki 6.918 nM
CNC(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL1627 Ki 7.0 nM
COc1cccc(N(NC2=NCCN2)c2ccc(C)cc2)c1 CHEMBL362954 Ki 7.3 nM
COc1cc2c(cc1OC)C1=NOC(CN3CCN(C/C(C)=C/c4ccccc4)CC3)C1CO2 CHEMBL93171 Ki 7.5 nM
CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@@H]2c3cccc4c3c(cn4C)C[C@H]21 CHEMBL19215 Ki 7.516 nM
Cc1ccc(N(CC2=NCCN2)c2cccc(O)c2)cc1 CHEMBL597 Ki 7.6 nM
O=C(NCCN1CCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1 CHEMBL478026 Ki 8.0 nM
CNc1cc[n+](CCNC(=O)c2ccn3c(-c4cccnc4OC)cnc3c2)cc1 CHEMBL5439393 IC50 8.0 nM
CN(C)CCCN1c2ccccc2Sc2ccccc21 CHEMBL564 Ki 8.418 nM
Cc1c(NC2=NCCN2)ccc2nccnc12 CHEMBL49137 Log Ki 8.913 nM
Cc1noc(C)c1-c1cnc2cc(C(=O)NCC[n+]3ccc(N(C)C)cc3)ccn12 CHEMBL5438314 IC50 9.0 nM
C1CCCC(NC2=NCCO2)CC1 CHEMBL305928 Log Ki 9.772 nM
CCO[C@H]1c2ccccc2[C@H]2C[C@]21c1c[nH]cn1 CHEMBL1256565 pKi 9.772 nM
Oc1cc2c(cc1O)C1c3ccccc3CNC1CO2 CHEMBL217299 Ki 10.0 nM
CCCCOc1ncccc1C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1 CHEMBL514837 Ki 10.5 nM
O=C1NCN(c2ccccc2)C12CCN(CC1COc3ccccc3O1)CC2 CHEMBL300555 Ki 10.67 nM
Cc1nc2ccccn2c(=O)c1CCCN1CCc2oc3ccccc3c2C1 CHEMBL165776 pIC50 10.72 nM
CCCCOc1cccc(C(=O)NCCN2CCCN(CC3COc4ccccc4O3)CC2)n1 CHEMBL476569 Ki 10.9 nM
COc1cccc2c1CCC[C@H]2CN(C)CCc1ccc2ccoc2c1 CHEMBL268258 Ki 11.0 nM
CN1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1 CHEMBL42 Ki 11.0 nM
Cc1nc2ccccn2c(=O)c1CCN1CCc2sc3ccccc3c2C1 CHEMBL165181 pIC50 11.48 nM
CC(C)O[C@H]1c2ccccc2[C@H]2C[C@]21c1c[nH]cn1 CHEMBL1256608 pKi 11.75 nM
COc1ccc2c(c1)C1=NOC(CN3CCN(C/C=C/c4ccccc4)CC3)C1CO2 CHEMBL422597 Ki 12.0 nM
CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C=C4c5cccc6[nH]cc(c56)C[C@H]4N(C)C3)(C(C)C)C(=O)N12 CHEMBL1403281 Ki 12.0 nM
CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc21 CHEMBL71 Ki 12.0 nM
CO[C@@H]1[C@@H](OC)[C@H](C)[C@@](O)(CC(=O)O)O[C@H]1[C@H](C)[C@H]1O[C@@]2(CC[C@@](C)([C@H]3CC[C@@](C)([C@@H]4O[C@@H]([C@H]5O[C@](C)(O)[C@H](C)C[C@@H]5C)C[C@@H]4O[C@@H]4C[C@H](OC)[C@@H](OC)[C@H](C)O4)O3)O2)C[C@H](O)[C@H]1C CHEMBL1909065 Ki 12.0 nM
Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2 CHEMBL85 Ki 12.0 nM
NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL1437 AC50 12.0 nM
Cc1cccc([C@H](C)c2c[nH]cn2)c1C CHEMBL2106195 Ki 12.14 nM
COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC CHEMBL2 Ki 13.0 nM
OCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 CHEMBL726 Ki 13.0 nM
CN1C[C@H](C(=O)N[C@]2(C)O[C@@]3(O)[C@@H]4CCCN4C(=O)[C@H](Cc4ccccc4)N3C2=O)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL1200517 Ki 13.57 nM
CN1CCc2c(Cl)ccc3oc(Br)c(c23)C1 CHEMBL123138 Ki 14.0 nM
COc1cc2c(cc1OC)C1=NO[C@@H](CN3CCN(C/C=C/c4ccccc4)CC3)[C@@H]1CO2 CHEMBL328114 Ki 14.0 nM
COc1cc2c(cc1OC)C1=NO[C@@H](CN3CCN(Cc4ccc5ccccc5c4)CC3)[C@@H]1CO2 CHEMBL92860 Ki 14.0 nM
COc1cc2c(cc1OC)C1=NO[C@@H](CN3CCN(C/C=C(\C)c4ccccc4)CC3)[C@@H]1CO2 CHEMBL419316 Ki 14.0 nM
COc1cc2c(cc1OC)C1=NOC(CN3CCN(C/C=C/c4ccc(F)cc4)CC3)C1CO2 CHEMBL226636 Ki 14.0 nM
CNc1cc[n+](CCNC(=O)c2ccn3c(-c4c(C)noc4C)cnc3c2)cc1 CHEMBL5410211 IC50 14.0 nM
O=C(NCCN1CCCN(C[C@H]2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1 CHEMBL524153 Ki 14.3 nM
CCc1sc2ccc(Cl)c3c2c1CN(C)CC3 CHEMBL123448 Ki 15.0 nM
COC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL537669 Ki 15.0 nM
CNc1cc[n+](CC(=O)Nc2ccc3c(c2)ncn3-c2ccccc2OC)cc1 CHEMBL5430221 IC50 15.0 nM
CNc1cc[n+](CC(=O)Nc2ccc3c(c2)ncn3-c2c(C)noc2C)cc1 CHEMBL5436779 IC50 15.0 nM
COC(=O)[C@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@H]2CC[C@@H]1O CHEMBL1257131 Ki 15.68 nM
CN1CCc2cccc(Cl)c2CC1 CHEMBL123349 Ki 16.0 nM
COc1ccc2c(c1)OCC1C2=NOC1CN1CCN(C/C=C/c2ccccc2)CC1 CHEMBL90247 Ki 16.0 nM
CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C=C4c5cccc6[nH]c(Br)c(c56)C[C@H]4N(C)C3)(C(C)C)C(=O)N12 CHEMBL493 Ki 16.0 nM
COc1ccccc1N1CCN(CC2COc3ccccc3O2)CC1 CHEMBL518592 Ki 17.0 nM
CN1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1 CHEMBL516 Ki 17.0 nM
O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1 CHEMBL476774 Ki 17.9 nM
Cc1ccc(N(NC2=NCCN2)c2cccc(O)c2)cc1 CHEMBL194849 Ki 18.0 nM
CC(C)[C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@](NC(=O)[C@@H]3C[C@@H]4c5cccc6[nH]cc(c56)C[C@H]4N(C)C3)(C(C)C)C(=O)N12 CHEMBL2365712 AC50 18.0 nM
O=C(NCCCCCCCCCCCCNC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL551711 Ki 18.5 nM
O=C(NCCCCCCCCCCNC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL554019 Ki 18.6 nM
c1ccc2c(c1)OCC(C1=NCCN1)O2 CHEMBL10316 pIC50 19.5 nM
CNc1cc[n+](CC(=O)Nc2ccc3c(c2)ncn3-c2c(C)nsc2C)cc1 CHEMBL5414112 IC50 21.0 nM
c1ccc([C@H]2CCCC[C@@H]2NC2=NCCO2)cc1 CHEMBL297228 Log Ki 22.39 nM
Fc1ccc2c(c1)CC(CC1CN=CN1)C2 CHEMBL90997 Ki 23.0 nM
[11CH3]OCc1cccnc1N1CCN(C[C@H]2COc3ccccc3O2)CC1 CHEMBL4297337 Kd 23.0 nM
CO[C@@H]1c2ccccc2[C@H]2C[C@]21c1c[nH]cn1 CHEMBL1256502 pKi 23.99 nM
CC(CN1c2ccccc2Sc2ccccc21)N(C)C CHEMBL643 Ki 24.0 nM
CN1CCN2c3ccccc3Cc3ccccc3C2C1 CHEMBL6437 Ki 24.0 nM
Cc1cc(C)nc(NS(=O)(=O)c2ccc(NCc3c(Cl)cccc3Cl)cc2)n1 CHEMBL5426976 IC50 24.0 nM
CNc1cc[n+](CCNC(=O)c2ccn3c(-c4c(C)noc4C)cnc3c2)cc1 CHEMBL5395039 IC50 24.0 nM
c1ccc2c(c1)CCCC2NC1=NCCCO1 CHEMBL306377 Log Ki 25.12 nM
COc1cc2nc(N3CCN(C(=O)C4CCCO4)CC3)nc(N)c2cc1OC CHEMBL611 Ki 26.0 nM
N#Cc1cccc(Oc2ncccc2C(=O)NCCN2CCCN(CC3COc4ccccc4O3)CC2)c1 CHEMBL515331 Ki 27.5 nM
O=C(NCCCCCCCNC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL543232 Ki 27.6 nM
COc1cccc(OC)c1OCCNCC1COc2ccccc2O1 CHEMBL25554 Ki 28.0 nM
CC(C)(C)Nc1ncccc1C(=O)NCCN1CCCN(CC2COc3ccccc3O2)CC1 CHEMBL477608 Ki 28.0 nM
COc1ccccc1-n1cnc2cc(NC(=O)CN(C)C)ccc21 CHEMBL5439467 IC50 28.0 nM
CCCN1C[C@H](CSC)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL531 Ki 29.0 nM
COc1ccc(CCN(CCCc2ccccc2)CCc2ccc3c(c2)OCO3)cc1OC CHEMBL3735756 Ki 29.0 nM
COc1ccccc1-n1cnc2cc(NC(C)=O)ccc21 CHEMBL1714607 IC50 29.0 nM
CNc1cc[n+](CCNC(=O)c2ccn3c(-c4c(C)cnn4C)cnc3c2)cc1 CHEMBL5415183 IC50 29.0 nM
CN1[C@@H]2CC[C@H]1C[C@@H](OC(c1ccccc1)c1ccccc1)C2 CHEMBL1201203 Ki 30.0 nM
COc1cc2c(cc1OC)C1=NOC(CN3CCN(C/C=C(\C)c4ccccc4)CC3)C1CO2 CHEMBL327875 Ki 31.0 nM
CN(C)CCC=C1c2ccccc2COc2ccccc21 CHEMBL1628227 Ki 32.0 nM
c1ccc(CCC[C@H]2CCCC[C@@H]2NC2=NCCO2)cc1 CHEMBL50720 Log Ki 32.36 nM
Brc1c(NC2=NCCN2)ccc2nccnc12 CHEMBL844 Log Ki 34.67 nM
CCn1nccc1-n1cnc2cc(NC(=O)C[n+]3ccc(NC)cc3)ccc21 CHEMBL5434845 IC50 39.0 nM
c1ccc(C[C@H]2C3CCC(C3)[C@H]2NC2=NCCO2)cc1 CHEMBL295186 Log Ki 40.74 nM
c1ccc(C[C@H]2CCCC[C@@H]2NC2=NCCO2)cc1 CHEMBL50719 Log Ki 40.74 nM
COc1cc2c(cc1OC)C1=NOC(CN3CCN(CCCc4ccccc4)CC3)C1CO2 CHEMBL90419 Ki 42.0 nM
COc1cc2c(cc1OC)C1=NOC(CN3CCN(C/C=C/c4ccccc4)CC3)C1CO2 CHEMBL93489 Ki 42.0 nM
Ic1c(NC2=NCCN2)ccc2nccnc12 CHEMBL70676 Log Ki 42.66 nM
C1COC(NC(C2CC2)C2CC2)=N1 CHEMBL289480 pKi 42.66 nM
COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12 CHEMBL723 Ki 43.0 nM
CNCCC=C1c2ccccc2CCc2ccccc21 CHEMBL445 Ki 43.0 nM
O=C(NCCCCCCCCCNC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL539606 Ki 44.7 nM
Cc1ccc2c(c1)c1c(n2CCc2ccc(C)nc2)CCN(C)C1 CHEMBL589390 Ki 45.77 nM
OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1 CHEMBL716 Ki 45.8 nM
O=C(NCCCCCCCCNC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL538808 Ki 46.0 nM
CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc21 CHEMBL415 Ki 46.0 nM
Nc1ccc(CNc2ccncc2)c(F)c1 CHEMBL5397377 EC50 46.0 nM
[2H]c1c([2H])c([2H])c([C@@H]2C[C@@H](N3CCN(C([2H])([2H])[2H])C(C)(C)C3)c3cc(Cl)ccc32)c([2H])c1[2H] CHEMBL5191141 Ki 47.0 nM
c1ccc(OC(C2=NCCN2)c2ccccc2)cc1 CHEMBL494885 pKi 47.86 nM
Brc1c(NC2=NCCN2)ccc2c1NCCN2 CHEMBL74283 Log Ki 48.98 nM
COc1cc2c(cc1OC)C1=NOC(CN3CCN(Cc4ccc5ccccc5c4)CC3)C1CO2 CHEMBL94129 Ki 49.0 nM
O=C(NCCN1CCCN(CC2COc3ccccc3O2)CC1)c1cccnc1Oc1ccccc1 CHEMBL477816 Ki 49.0 nM
CNc1cc[n+](CCNC(=O)c2ccn3c(-c4c(C)noc4C)cnc3c2)c(C)c1 CHEMBL5414548 IC50 49.0 nM
COc1ccccc1-n1cnc2cc(NC(=O)CCc3cccnc3)ccc21 CHEMBL5405285 IC50 55.0 nM
COc1ccccc1N1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 CHEMBL51433 Ki 56.0 nM
CC(=O)c1ccc2c(c1)N(CCCN1CCN(CCO)CC1)c1ccccc1S2 CHEMBL1085 AC50 56.0 nM
Cn1c(=O)cnn(CCCCN2CCN(c3ccccc3OCCF)CC2)c1=O CHEMBL2413153 Ki 56.2 nM
CNc1cc[n+](CCNC(=O)c2ccc3c(c2)ncn3-c2c(C)noc2C)cc1 CHEMBL5425371 IC50 59.0 nM
CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc21 CHEMBL285802 AC50 60.5 nM
CCCc1ccccc1COC1=NCCN1 CHEMBL569933 pEC50 61.66 nM
CC(Oc1c(Cl)cccc1Cl)C1=NCCN1 CHEMBL17860 pKi 67.61 nM
CCCN[C@H]1CCc2nc(N)sc2C1 CHEMBL301265 Ki 67.7 nM
N=C(N)N/N=C/c1c(Cl)cccc1Cl CHEMBL420 Ki 68.0 nM
CC(=O)c1ccc2c(c1)N(CCCN1CCC(CCO)CC1)c1ccccc1S2 CHEMBL1584 AC50 68.0 nM
Clc1c(NC2=NCCN2)ccc2nccnc12 CHEMBL72753 Log Ki 69.18 nM
c1ccc(Oc2ncccc2COCCN2CCCN(CC3COc4ccccc4O3)CC2)cc1 CHEMBL491419 Ki 69.5 nM
CNc1cc[n+](CC(=O)Nc2cnc3c(c2)ncn3-c2ccccc2OC)cc1 CHEMBL5425547 IC50 71.0 nM
Fc1ccc2cnn(N=C3NCCN3)c2c1 CHEMBL3343699 Ki 72.0 nM
c1ccc(CN2CCN(CC3CCc4ccccc4O3)CC2)cc1 CHEMBL179648 Ki 72.8 nM
c1ccc2sc(SSc3nc4ccccc4s3)nc2c1 CHEMBL508112 Ki 74.0 nM
CN1CCN(CC/C=C2/c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1 CHEMBL1201 AC50 78.0 nM
c1ccc2c(c1)cnn2N=C1NCCN1 CHEMBL1186220 Ki 79.0 nM
Cc1nc2ccccn2c(=O)c1CCN1CCc2oc3ccc(Cl)cc3c2C1 CHEMBL165677 pIC50 79.43 nM
CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc21 CHEMBL809 Ki 82.8 nM
CCNc1cc[n+](CCNC(=O)c2ccn3c(-c4c(C)noc4C)cnc3c2)cc1 CHEMBL5421131 IC50 86.0 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)CC2)C1c1ccc(Cl)c([N+](=O)[O-])c1 CHEMBL327931 Log Ki 91.2 nM
CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 CHEMBL296660 Log Ki 91.2 nM
CCc1c(C)[nH]c2c1C(=O)C(CN1CCOCC1)CC2 CHEMBL460 AC50 93.1 nM
CCc1cc[n+](CCNC(=O)c2ccn3c(-c4c(C)noc4C)cnc3c2)cc1 CHEMBL5408602 IC50 94.0 nM
Clc1cccc(Cl)c1NC1=NCCN1 CHEMBL1705 Ki 94.09 nM
Cc1nc2ccccc2c(Nc2ccc(N3CCN(C)CC3)cc2)c1Cc1ccccc1 CHEMBL384925 Ki 96.0 nM
COc1ccccc1-n1cnc2cc(NC(=O)CCc3ccncc3)ccc21 CHEMBL5429032 IC50 97.0 nM
c1nc(C2CCCc3sccc32)c[nH]1 CHEMBL284213 Ki 99.0 nM
COc1ccccc1N1CCN(CCN2C(=O)c3ccccc3C(C)(C)C2=O)CC1 CHEMBL362051 IC50 99.0 nM
Cc1sc(C)c2c1CCC=C2c1c[nH]cn1 CHEMBL284795 Ki 100.0 nM
Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1 CHEMBL715 pKi 100.0 nM
CNc1ccc[n+](CCNC(=O)c2ccn3c(-c4c(C)noc4C)cnc3c2)c1 CHEMBL5422664 IC50 100.0 nM
O=C(CCCN1CC=C(n2c(=O)[nH]c3ccccc32)CC1)c1ccc(F)cc1 CHEMBL1108 Ki 101.0 nM
C(=C/c1ccccc1)\C[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 CHEMBL297827 Log Ki 102.33 nM
COc1cc(C(C)=O)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1 CHEMBL14376 AC50 105.5 nM
Cc1nn(C)c(C)c1-c1cccc2c1CC[C@H](N(C)C)C2 CHEMBL2164327 Ki 108.05 nM
N=C(N)NC(=O)Cc1c(Cl)cccc1Cl CHEMBL862 Ki 114.0 nM
COC(=O)C1=CO[C@@H](C)[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@H]3C[C@H]12 CHEMBL122404 Ki 116.0 nM
COc1ccccc1N1CCN(C[C@H]2CN=C3c4ccccc4NC(=O)N32)CC1 CHEMBL1788222 Ki 116.0 nM
CCCN(CCc1cccs1)[C@H]1CCc2c(O)cccc2C1 CHEMBL1303 AC50 130.0 nM
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1 CHEMBL540612 Ki 131.74 nM
C[C@@H](CO)NC(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1 CHEMBL119443 Ki 132.0 nM
CNCCCC12CCC(c3ccccc31)c1ccccc12 CHEMBL21731 Ki 133.0 nM
O=C(NCCCCCNC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL555190 Ki 134.3 nM
Clc1ccccc1CN1CCc2sccc2C1 CHEMBL833 Ki 139.0 nM
COc1ccc2c3c([nH]c2c1)CNCC3 CHEMBL6310 Ki 140.0 nM
CN(C)C/C=C(/c1ccc(Br)cc1)c1cccnc1 CHEMBL37744 AC50 140.0 nM
OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1 CHEMBL567 AC50 140.0 nM
Cc1sc(C)c2c1CCCC2c1c[nH]cn1 CHEMBL30739 Ki 141.0 nM
c1ccc(CCC[C@H]2C3CCC(C3)[C@H]2NC2=NCCO2)cc1 CHEMBL48341 Log Ki 141.25 nM
CC(C)=CCOc1ccc(Cl)c2c1CCN(C)CC2 CHEMBL114166 Ki 142.0 nM
CN1CCC[C@@H]1CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1 CHEMBL1626 Ki 142.0 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1 CHEMBL43491 Ki 145.0 nM
CN1CCN(CCCN2c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1 CHEMBL609109 AC50 150.0 nM
CNc1cc[n+](CCNC(=O)c2ccc3c(c2)nnn3-c2c(C)noc2C)cc1 CHEMBL5401268 IC50 157.0 nM
Fc1cccc2cnn(N=C3NCCN3)c12 CHEMBL3343700 Ki 158.0 nM
COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(-c4ccco4)cc13)CC2 CHEMBL392991 Ki 160.0 nM
Clc1ccc(N2CCN(Cc3c[nH]c4ncccc34)CC2)cc1 CHEMBL267014 Ki 160.0 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1 CHEMBL43860 Ki 162.0 nM
CC(Oc1ccccc1Cl)C1=NCCN1 CHEMBL1956191 pEC50 162.18 nM
CC(Oc1ccccc1)C1=NCCN1 CHEMBL273485 pKi 165.96 nM
CC(OC1=NCCN1)c1ccccc1 CHEMBL571314 pKi 165.96 nM
O=C(NCCCCCCNC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL542527 Ki 166.2 nM
C=CCN(CC=C)CCc1c[nH]c2ccc(Cl)cc12 CHEMBL3752900 pKi 169.82 nM
C#CCN(C)[C@H](C)Cc1ccccc1 CHEMBL972 Ki 172.0 nM
CSc1ccc2c(c1)N(CCC1CCCCN1C)c1ccccc1S2 CHEMBL479 Ki 174.0 nM
O=c1n(CCCN2CCN(c3cccc(Cl)c3)CC2)nc2ccccn12 CHEMBL621 Ki 178.0 nM
CN1CCCC(CN2c3ccccc3Sc3ccccc32)C1 CHEMBL395110 Ki 181.0 nM
Cc1cccc(C)c1OC(C)C1=NCCN1 CHEMBL155866 pKi 181.97 nM
O=C(NCCCCNC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL539824 Ki 188.6 nM
c1ccc2c(CC3=NCCN3)cccc2c1 CHEMBL761 AC50 190.0 nM
CC(Oc1ccccc1C1CCCCC1)C1=NCCN1 CHEMBL451229 pKi 190.55 nM
CC(Oc1ccccc1C1CCCC1)C1=NCCN1 CHEMBL495096 pKi 190.55 nM
O=c1ccc2ccc(OCCCCN3CCN(c4cccc5sccc45)CC3)cc2[nH]1 CHEMBL2105760 Ki 191.49 nM
CCc1nn(CCCN2CCN(c3cccc(Cl)c3)CC2)c(=O)n1CCOc1ccccc1 CHEMBL1200492 Ki 192.4 nM
COc1cc2nc(C)c(CCN3CCc4oc5ccccc5c4C3)c(=O)n2cc1OC CHEMBL162058 pIC50 194.98 nM
CC1=C(C(=O)O)C(c2ccc3c(c2)OCO3)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(C)N1 CHEMBL313251 Log Ki 199.53 nM
CC(Oc1c(-c2ccccc2)cccc1-c1ccccc1)C1=NCCN1 CHEMBL1956203 pEC50 199.53 nM
CN1CCC2C(C1)c1cccc3c1N2c1ccccc1CS3 CHEMBL3217984 pKi 199.53 nM
CC1=C(C(N)=O)C(c2ccc3c(c2)OCO3)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(C)N1 CHEMBL312871 Log Ki 204.17 nM
Cc1cc(C(C)(C)C)cc(C)c1CC1=NCCN1 CHEMBL312448 AC50 207.8 nM
CC[C@@H](CO)NC(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1 CHEMBL1201356 Ki 210.0 nM
CC(Oc1ccccc1-c1cccs1)C1=NCCN1 CHEMBL223829 Log Ki 213.8 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL91022 Log Ki 218.78 nM
c1cnc2cc(NC3=NCCN3)ccc2n1 CHEMBL49395 Log Ki 218.78 nM
C=CCN(CC=C)CCc1c[nH]c2ccc(F)cc12 CHEMBL3754496 pKi 218.78 nM
CN1CCN2c3ncccc3Cc3ccccc3C2C1 CHEMBL654 pIC50 223.87 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(COCCN=[N+]=[N-])N1 CHEMBL98063 Ki 229.0 nM
C=CCN(CC=C)CCc1c[nH]c2ccc(Br)cc12 CHEMBL3754166 pKi 229.09 nM
O=C1[C@@H]2[C@H]3CC[C@H](C3)[C@@H]2C(=O)N1C[C@@H]1CCCC[C@H]1CN1CCN(c2nsc3ccccc23)CC1 CHEMBL1237021 AC50 230.0 nM
CN1CCCC(n2nc(Cc3ccc(Cl)cc3)c3ccccc3c2=O)CC1 CHEMBL1200809 Ki 230.35 nM
NC[C@H](O)c1ccc(O)c(O)c1 CHEMBL5087452 Ki 234.7 nM
CN1C2CCC1CC(OC(c1ccc(F)cc1)c1ccc(F)cc1)C2 CHEMBL543113 Ki 235.5 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(CCCCOC)N1 CHEMBL99864 Ki 237.0 nM
COc1ccccc1N1CCN(CCCCn2ncc(=O)n(C)c2=O)CC1 CHEMBL2413154 Ki 238.0 nM
CC(Oc1ccccc1C(F)(F)F)C1=NCCN1 CHEMBL1956193 pEC50 239.88 nM
COc1ccccc1N1CCN(CCCSc2nnc(-c3ccccc3)n2C)CC1 CHEMBL4083252 Ki 241.0 nM
NC1=Nc2ccc(Cl)cc2CN1 CHEMBL2436555 Ki 243.0 nM
COc1cc2[nH]c(C)c(CCN3CCN(c4ccccc4)CC3)c2cc1OC CHEMBL2107011 AC50 250.0 nM
Clc1cc(Cl)c(OCC#CI)cc1Cl CHEMBL1289 Ki 251.0 nM
CC(Oc1ccccc1C(C)C)C1=NCCN1 CHEMBL266613 pEC50 251.19 nM
COc1cc2c3c(c1OC)-c1cc4c(cc1CC3N(C)CC2)OCO4 CHEMBL467094 Ki 252.0 nM
COc1ccccc1N1CCN(CC2CN3C(=O)Nc4ccccc4C3=N2)CC1 CHEMBL302021 Ki 253.0 nM
Clc1ccc2c(c1)C(N1CCNCC1)=Nc1ccccc1O2 CHEMBL1113 Ki 255.0 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(CC)N1 CHEMBL91550 Log Ki 257.04 nM
CNc1cc(OC)c(C(=O)NC2CCN(Cc3ccccc3)C2C)cc1Cl CHEMBL20734 AC50 260.0 nM
C[C@H](Oc1ccccc1C1CC1)C1=NCCN1 CHEMBL1276220 pKi 263.03 nM
CC(Oc1ccccc1-c1cccc(F)c1)C1=NCCN1 CHEMBL223836 Log Ki 269.15 nM
Cc1ccccc1C(C)OC1=NCCN1 CHEMBL570863 pKi 269.15 nM
CCc1cccc(CC)c1OC(C)C1=NCCN1 CHEMBL157955 pKi 269.15 nM
COc1ccc2cc3[n+](cc2c1OC)CCc1cc2c(cc1-3)OCO2 CHEMBL12089 Ki 274.0 nM
CC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(C)N1 CHEMBL279436 Ki 275.0 nM
C=CCc1cccc(CC=C)c1OC(C)C1=NCCN1 CHEMBL157206 pKi 275.42 nM
CCc1ccccc1OC(C)C1=NCCN1 CHEMBL156336 pKi 281.84 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(COC)N1 CHEMBL100045 Ki 288.0 nM
CC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1C CHEMBL288772 Ki 288.0 nM
CNc1cc[n+](CC(=O)Nc2ccc3c(c2)ncn3-c2ccnn2C)cc1 CHEMBL5420616 IC50 290.0 nM
Clc1ccc2nsnc2c1NC1=NCCN1 CHEMBL1079 AC50 292.2 nM
CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1 CHEMBL221753 Ki 294.0 nM
O=C1NCN(c2ccccc2)C12CCN(CCCOc1ccc(F)cc1)CC2 CHEMBL79834 Ki 294.27 nM
CC(=O)c1ccccc1OC(C)C1=NCCN1 CHEMBL1956202 pEC50 295.12 nM
COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(-c4ccccc4F)cc13)CC2 CHEMBL393597 Ki 299.0 nM
COc1ccccc1N1CCN(CC(O)COc2cccc3ccccc23)CC1 CHEMBL142635 AC50 300.0 nM
C=CCN(CC=C)CCc1c[nH]c2ccccc12 CHEMBL3752576 pKi 302.0 nM
CC(OC1=NCCN1)c1ccccc1C1CC1 CHEMBL576623 pKi 309.03 nM
CC(Oc1ccccc1C1CC1)C1=NCCN1 CHEMBL1276218 pKi 309.03 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 CHEMBL1256844 Ki 310.99 nM
COc1cc2c(cc1OC)C1=NOC(CN3CCN(CC4=Cc5ccccc5C4)CC3)C1CO2 CHEMBL328377 Ki 315.0 nM
Cn1c(=O)cnn(CCCCN2CCN(c3cccc4ccc(O[11CH3])cc34)CC2)c1=O CHEMBL199824 Ki 316.2 nM
C[C@@H](Oc1ccccc1-c1cccc(O)c1)C1=NCCN1 CHEMBL1278084 pKi 316.23 nM
CC(Oc1ccccc1Br)C1=NCCN1 CHEMBL1956192 pEC50 316.23 nM
CC(Oc1ccccc1C=O)C1=NCCN1 CHEMBL1956201 pEC50 316.23 nM
CN(C)CCCN1c2ccccc2CCc2ccccc21 CHEMBL11 AC50 320.0 nM
CCC(=O)c1ccc2c(c1)N(CC(C)N(C)C)c1ccccc1S2 CHEMBL1201210 AC50 320.0 nM
OCCN1CCN(CC/C=C2/c3ccccc3Sc3ccc(Cl)cc32)CC1 CHEMBL53904 AC50 320.0 nM
Cc1cnc2c(Br)c(NC3=NCCN3)ccc2n1 CHEMBL72147 Log Ki 323.59 nM
CN1CCC(=C2c3ccccc3CC(=O)c3sccc32)CC1 CHEMBL534 Ki 324.0 nM
COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(-c4ccccn4)cc13)CC2 CHEMBL246229 Ki 330.0 nM
CSc1ccc(F)cc1NCC1=NCCN1 CHEMBL72768 Log Ki 331.13 nM
CC(C)(C)c1ccc(C(=O)CCCN2CCC(OC(c3ccccc3)c3ccccc3)CC2)cc1 CHEMBL305660 Ki 337.3 nM
C=CCc1ccccc1OC(C)C1=NCCN1 CHEMBL495095 pKi 338.84 nM
C=CCc1ccccc1C(C)OC1=NCCN1 CHEMBL570973 pKi 338.84 nM
C[C@@H](Oc1ccccc1CC1CC1)C1=NCCN1 CHEMBL2089155 pKi 338.84 nM
O=C1CCc2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1 CHEMBL1112 AC50 339.1 nM
CCc1nn(CCCN2CCN(c3cccc(Cl)c3)CC2)c(=O)n1CCOc1ccccc1 CHEMBL623 AC50 340.0 nM
Cn1cc(C(=O)[C@@H]2CCc3[nH]cnc3C2)c2ccccc21 CHEMBL1643895 AC50 340.0 nM
CC(Oc1ccccc1-c1cccc(O)c1)C1=NCCN1 CHEMBL374584 Log Ki 354.81 nM
c1ccc(N2CCN(CCCc3nc4ccccc4s3)CC2)nc1 CHEMBL5400876 Ki 358.0 nM
O=C1COc2cc(CN3CCN(c4ccc(Cl)cc4)CC3)ccc2N1 CHEMBL346389 Ki 368.0 nM
COc1cc2c(cc1OC)C1=NOC(CN3CCN(Cc4csc5ccccc45)CC3)C1CO2 CHEMBL93801 Ki 370.0 nM
COc1cc2c(cc1OC)CN(Cc1cnc(N)n3nc(-c4ccco4)nc13)CC2 CHEMBL246228 Ki 370.0 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL284470 Log Ki 371.54 nM
Brc1c(NC2=NCCN2)ccc2nccnc12 CHEMBL1200389 Ki 372.74 nM
COc1ccccc1N1CCN(C[C@H]2CN=C3c4ccccc4N=C(SC)N32)CC1 CHEMBL1788223 Ki 376.0 nM
CC(C)C1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(C(C)C)N1 CHEMBL313953 Log Ki 380.19 nM
CC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc2c(c1)OCO2 CHEMBL88388 Log Ki 380.19 nM
C=CCOc1cc(F)c(F)cc1C1CC1CN CHEMBL3769968 pKi 380.19 nM
COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC CHEMBL1558 Ki 396.5 nM
CNC[C@H](O)c1ccc(O)c(O)c1 CHEMBL679 Ki 397.0 nM
Cc1ccc(-c2ccccc2OC(C)C2=NCCN2)cc1 CHEMBL426900 Log Ki 398.11 nM
Cc1ccccc1COC1=NCCN1 CHEMBL576819 pKi 398.11 nM
C=CCc1ccccc1O[C@@H](C)C1=NCCN1 CHEMBL1276140 pKi 398.11 nM
CC[C@H]1c2ccccc2N(c2ccccc2)C[C@@]1(C)N CHEMBL4572167 pKi 398.11 nM
OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL47050 Ki 401.0 nM
COc1ccccc1N1CCN(CCCNc2c(C)c(=O)n(C)c(=O)n2C)CC1 CHEMBL420060 Ki 406.0 nM
CC(Oc1ccccc1CC1CC1)C1=NCCN1 CHEMBL1956195 pKi 407.38 nM
C[C@H](Oc1ccccc1CC1CC1)C1=NCCN1 CHEMBL2089156 pKi 407.38 nM
CN1CCc2c(c3cccc4c3n2-c2ccccc2CC4)C1 CHEMBL3104091 Ki 413.0 nM
CC(Oc1ccccc1-c1ccsc1)C1=NCCN1 CHEMBL385310 Log Ki 416.87 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)[C@H]1c1cccc([N+](=O)[O-])c1 CHEMBL405355 Ki 420.0 nM
CC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(C)N1 CHEMBL180561 Ki 420.0 nM
CN1CCN(c2ccc(Nc3c(CO)cnc4cc(Cl)ccc34)cc2)CC1(C)C CHEMBL216464 Ki 420.0 nM
CN1CCN(c2ccnc(NCCc3ccccc3)n2)CC1 CHEMBL4748908 pKi 426.58 nM
CC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL89685 Log Ki 436.52 nM
C=CCN(CC=C)CCc1c[nH]c2ccc(C)cc12 CHEMBL3753318 pKi 436.52 nM
CC(C(O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 CHEMBL305187 AC50 440.0 nM
CCO/N=C/c1ccccc1OC(C)C1=NCCN1 CHEMBL492639 pKi 446.68 nM
C[C@H](Oc1ccccc1-c1ccsc1)C1=NCCN1 CHEMBL1276248 pKi 446.68 nM
CN1CCN(c2ccc3c(c2)CN(C(=O)OCc2ccccc2)C3)CC1 CHEMBL4163428 Ki 454.0 nM
COC(=O)[C@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL31410 Ki 455.0 nM
Cc1ccc(C(=O)C(C)CN2CCCCC2)cc1 CHEMBL1076211 Ki 456.0 nM
CC(Oc1ccccc1-c1cccc(N)c1)C1=NCCN1 CHEMBL222371 Log Ki 478.63 nM
c1ccc(-c2cccc3c2OC(C2=NCCN2)CO3)cc1 CHEMBL522151 pKi 478.63 nM
CNc1cc[n+](CC(=O)Nc2ccc3c(cnn3-c3ccccc3OC)n2)cc1 CHEMBL5426694 IC50 480.0 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)N(C)CCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL88448 Log Ki 489.78 nM
[2H]c1c([2H])c([2H])c([C@@H]2C[C@@H](N3CCNC(C)(C)C3)c3cc(Cl)ccc32)c([2H])c1[2H] CHEMBL5201983 Ki 490.0 nM
CC(Oc1ccccc1-c1ccccc1)C1=NCCN1 CHEMBL128168 Log Ki 501.19 nM
CC(Oc1ccccc1-c1ccc([N+](=O)[O-])cc1)C1=NCCN1 CHEMBL221523 Log Ki 501.19 nM
c1ccc(OCC2=NCCN2)c(CC2CC2)c1 CHEMBL2431281 pKi 501.19 nM
CCCC1=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCC)=C(CC)N1 CHEMBL316495 Ki 507.0 nM
CN1CCC(=C2c3ccccc3CCc3sccc32)CC1 CHEMBL294951 AC50 510.0 nM
S=C(NCCCc1c[nH]cn1)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1 CHEMBL103769 Ki 511.57 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL91956 Log Ki 512.86 nM
O=C(CCCN1C2CCC1CC(O)(c1ccc(Cl)cc1)C2)c1ccc(F)cc1 CHEMBL210578 Ki 515.5 nM
COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CCCOc2ccc(F)cc2)CC1OC CHEMBL1729 Ki 524.0 nM
c1ccc(C2CC2)c(OCC2=NCCN2)c1 CHEMBL13852 pKi 524.81 nM
Cc1ccccc1N1CCN(CCc2nnc3n2CCCC3)CC1 CHEMBL1201216 Ki 526.0 nM
O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c1ccccc1 CHEMBL279516 Ki 528.0 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3F)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1 CHEMBL295001 Ki 531.0 nM
Cc1cccc(-c2ccccc2OC(C)C2=NCCN2)c1 CHEMBL222973 Log Ki 537.03 nM
CCCc1ccccc1C(C)OC1=NCCN1 CHEMBL576078 pKi 537.03 nM
CCCc1ccccc1OC(C)C1=NCCN1 CHEMBL2431282 pKi 537.03 nM
CNc1cc[n+](CCCNC(=O)c2ccn3c(-c4c(C)noc4C)cnc3c2)cc1 CHEMBL5438427 IC50 545.0 nM
CCCc1ccccc1OCC1=NCCN1 CHEMBL13917 pKi 549.54 nM
Oc1c(Cl)cc(Cl)cc1Sc1cc(Cl)cc(Cl)c1O CHEMBL290106 Ki 560.0 nM
C=CCc1ccccc1O[C@H](C)C1=NCCN1 CHEMBL1276139 pKi 562.34 nM
C[C@@H](Oc1ccccc1C1CC1)C1=NCCN1 CHEMBL1276219 pKi 562.34 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL290860 Ki 570.0 nM
COc1cc2c3c(c1OC)-c1ccccc1[C@@H](O)[C@@H]3NCC2 CHEMBL4285281 Ki 571.0 nM
CN(C)c1ccc(C(=C2C=CC(=[N+](C)C)C=C2)c2ccc(N(C)C)cc2)cc1 CHEMBL64894 Ki 574.0 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])c(OC)c1 CHEMBL313160 Log Ki 575.44 nM
CNC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc2c(c1)OCO2 CHEMBL88628 Log Ki 575.44 nM
Cc1ccc2c(Nc3ccc(N4CCN(C)C(C)C4)cc3)c(C)c(C)nc2c1C CHEMBL217203 Ki 580.0 nM
Cc1cc(C(C)(C)C)c(O)c(C)c1CC1=NCCN1 CHEMBL762 Ki 581.0 nM
COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(-c4cccc(C(=O)NCCN(C)C)c4)cc13)CC2 CHEMBL392771 Ki 584.0 nM
C[C@H](Oc1ccccc1-c1ccccc1)C1=NCCN1 CHEMBL396013 Log Ki 588.84 nM
Cc1ccc2c(Nc3ccc(N4CCN(C)[C@H](C)C4)cc3)c(C)c(C)nc2c1C CHEMBL217567 Ki 600.0 nM
OC1(c2ccc(Cl)cc2)CCN(Cc2c[nH]c3ccccc23)CC1 CHEMBL445102 Ki 602.14 nM
CN1CCC(=C2c3ccccc3CC(=O)c3sccc32)CC1 CHEMBL1633 Ki 602.42 nM
Brc1ccccc1OCC1=NCCN1 CHEMBL2431279 pKi 616.6 nM
O=C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 CHEMBL54 Ki 618.0 nM
C1=C(c2c[nH]cn2)c2ccsc2CC1 CHEMBL286246 Ki 621.0 nM
O=C1NCN(c2ccccc2)C12CCN(CCCC(c1ccc(F)cc1)c1ccc(F)cc1)CC2 CHEMBL46516 AC50 640.0 nM
CCn1ccnc1CC1COc2ccccc2O1 CHEMBL347695 IC50 655.0 nM
Cc1nc2sccn2c(=O)c1CCN1CCC(=C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL267777 Ki 655.32 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)[C@@H]1c1cccc([N+](=O)[O-])c1 CHEMBL2051956 Ki 660.0 nM
CC(Oc1ccccc1-c1cccc([N+](=O)[O-])c1)C1=NCCN1 CHEMBL222928 Log Ki 660.69 nM
c1cc(-c2c[nH]cn2)c2ccsc2c1 CHEMBL30534 Ki 663.0 nM
COc1cc(CN[C@H]2C3C4CC5C6C4CC3C6C52)cc(OC)c1OC CHEMBL2432051 Ki 665.0 nM
COc1ccc(NC(=O)c2ccc(-c3ccc(-c4noc(C)n4)cc3C)cc2)cc1OCCN(C)C CHEMBL5089005 Ki 666.5 nM
O=S1(=O)c2cccc3cccc(c23)N1CCCN1CCN(c2ccc(F)cc2)CC1 CHEMBL83894 Ki 666.96 nM
CCCCN1CCC(COC(=O)c2cc(Cl)c(NC)c3c2OCCO3)CC1 CHEMBL1258223 Ki 671.2 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3C#N)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1 CHEMBL42335 Ki 676.0 nM
CSc1ccc(Cl)cc1NCC1=NCCN1 CHEMBL70751 Log Ki 676.08 nM
COc1cc2/c(=N/c3ccc(Br)cc3F)nc[nH]c2cc1OCC1CCN(C)CC1 CHEMBL24828 AC50 682.3 nM
Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL118 Ki 692.0 nM
CNCCC(Oc1ccc(C(F)(F)F)cc1)c1ccccc1 CHEMBL41 Ki 698.0 nM
CC(Oc1ccccc1/C=N/O)C1=NCCN1 CHEMBL493675 pKi 707.95 nM
C[C@@H](Oc1ccccc1-c1ccsc1)C1=NCCN1 CHEMBL1276247 pKi 707.95 nM
C=CCc1ccccc1OCC1=NCCN1 CHEMBL14107 pKi 707.95 nM
NC(=O)C(c1ccccc1)(c1ccccc1)[C@@H]1CCN(CCc2ccc3c(c2)CCO3)C1 CHEMBL1346 AC50 720.0 nM
CN(C)CCc1c[nH]c2ccccc12 CHEMBL3183055 Ki 720.0 nM
COc1cc2c(cc1OC)C1=NOC(CN3CCN(Cc4ccc5ncccc5c4)CC3)C1CO2 CHEMBL90966 Ki 721.0 nM
CCN(CC)CCOc1ccc(/C(=C(/Cl)c2ccccc2)c2ccccc2)cc1 CHEMBL954 Ki 721.0 nM
C=CCN(CC=C)CCc1c[nH]c2ccc(OC)cc12 CHEMBL2391541 pKi 724.44 nM
CC(CCc1ccccc1)NC(C)C(O)c1ccc(O)cc1 CHEMBL114655 AC50 730.0 nM
C[C@@H](Oc1ccccc1-c1cccc([N+](=O)[O-])c1)C1=NCCN1 CHEMBL242693 Log Ki 741.31 nM
COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(-c4ccccc4)cc13)CC2 CHEMBL392992 Ki 752.0 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(COCC(F)(F)F)N1 CHEMBL320736 Ki 753.0 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)OCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL3392246 Ki 758.0 nM
Cc1cccc(C)c1NC(=O)CN1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL92870 AC50 760.0 nM
[2H]C([2H])(Cc1c[nH]c2ccccc12)N(C)C CHEMBL5398630 Ki 760.0 nM
Cc1c(C(=O)c2ccc(Cl)cc2)c2ccc(OC(F)(F)F)cc2n1Cc1cccc(O[C@H](C)C(=O)O)c1 CHEMBL461571 IC50 770.0 nM
CCCCN1CCC(COC(=O)c2cc(F)c(N)c3c2OCCO3)CC1 CHEMBL1258671 Ki 773.0 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1C CHEMBL291166 Ki 776.0 nM
CSc1ccccc1NCC1=NCCN1 CHEMBL540542 Log Ki 776.25 nM
Clc1ccccc1NCC1=NCCN1 CHEMBL51358 pEC50 776.25 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)[C@H]1c1ccc([N+](=O)[O-])cc1 CHEMBL179334 Ki 780.0 nM
C[C@H](Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)NCCOc1ccccc1OCC(F)(F)F CHEMBL24778 Ki 786.05 nM
CCOc1cc(N2CCC3(CC2)C(=O)Nc2ccc(Br)cc23)nnc1C(F)(F)F CHEMBL4483761 IC50 790.0 nM
COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C CHEMBL1219 Ki 793.0 nM
COC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL5483012 Log Ki 794.33 nM
c1ccc(OC2CC2)c(OCC2=NCCN2)c1 CHEMBL2431280 pKi 794.33 nM
O=C(OCCN1CCCC1)N1c2ccccc2Sc2ccccc21 CHEMBL481153 Ki 800.0 nM
COc1cccc(-c2cc3c(CN4CCc5cc(OC)c(OC)cc5C4)ccc(OC)c3o2)c1 CHEMBL246639 Ki 804.0 nM
CCCCCCCCCCCCCCCC[n+]1ccccc1 CHEMBL334255 Ki 812.0 nM
CC(Oc1ccccc1-c1ccc(O)cc1)C1=NCCN1 CHEMBL222798 Log Ki 812.83 nM
CNCc1ccccc1-c1csc([C@H](C)Nc2nc(C)nc3cc(OC)c(OC)cc23)c1 CHEMBL4520788 pKi 812.83 nM
Cc1cc(C(C#N)c2ccc(Cl)cc2)c(Cl)cc1NC(=O)c1cc(I)cc(I)c1O CHEMBL12131 Ki 821.9 nM
CC1=C(C#N)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(C)N1 CHEMBL327775 Log Ki 831.76 nM
Cc1ccccc1-c1ccccc1OC(C)C1=NCCN1 CHEMBL223830 Log Ki 831.76 nM
CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc2ccc(OC)cc12 CHEMBL7568 Ki 833.0 nM
CCCCC1CCN(CCCC(=O)c2ccccc2C)CC1 CHEMBL1242950 Ki 840.0 nM
O=C(CCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1)c1ccc(F)cc1 CHEMBL297302 AC50 850.0 nM
O=c1[nH]c2ccccc2n1CCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1 CHEMBL219916 AC50 850.0 nM
CSc1cc(F)ccc1NCC1=NCCN1 CHEMBL306792 Log Ki 851.14 nM
COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(C(=O)NC4CN5CCC4CC5)cc13)CC2 CHEMBL394218 Ki 857.0 nM
Fc1ccc(C(c2ccc(F)cc2)N2CCN(C/C=C/c3ccccc3)CC2)cc1 CHEMBL30008 Ki 864.0 nM
Cc1ccccc1C(OCCN(C)C)c1ccccc1 CHEMBL900 Ki 865.0 nM
CN(C)C/C=C/C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1 CHEMBL1173655 AC50 870.0 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc2c(c1)OCO2 CHEMBL91415 Log Ki 870.96 nM
CC(Oc1ccccc1/C=N/OCc1ccccc1)C1=NCCN1 CHEMBL495097 pKi 870.96 nM
C=C(C)c1ccccc1OC(C)C1=NCCN1 CHEMBL1956194 pKi 870.96 nM
COc1ccccc1OC(C)C1=NCCN1 CHEMBL1956199 pKi 870.96 nM
CC(C)(C)OC(=O)N1CCCC1CNC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1 CHEMBL4558518 pKi 870.96 nM
CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1 CHEMBL60889 Ki 871.0 nM
Cc1nc2cc(Cl)ccc2c(Nc2ccc(N3CCN(C)C(C)C3)cc2)c1C CHEMBL1689423 Ki 880.0 nM
NC[C@@H]1O[C@H](C23CC4CC(CC(C4)C2)C3)Cc2c1ccc(O)c2O CHEMBL1256876 Ki 889.5 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc2ccccc2c1 CHEMBL92322 Log Ki 891.25 nM
CCC1=C(C(N)=O)C(c2ccc([N+](=O)[O-])cc2)C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)=C(COCCN)N1 CHEMBL323579 Ki 902.0 nM
Cc1cc(C)c2c(Nc3ccc(N4CCN(C)C(C)C4)cc3)c(C)c(C)nc2c1 CHEMBL218730 Ki 910.0 nM
CNC(=O)C1=C(C)NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc([N+](=O)[O-])cc1 CHEMBL284103 Ki 912.0 nM
CO/C(O)=C1\C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(C)cc1 CHEMBL315914 Log Ki 912.01 nM
CC(Oc1ccccc1-c1cccnc1)C1=NCCN1 CHEMBL373535 Log Ki 933.25 nM
Clc1ccccc1NC1=NCCC1 CHEMBL2058633 pKi 933.25 nM
C1=C(c2c[nH]cn2)c2sccc2CC1 CHEMBL30955 Ki 940.0 nM
COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(-c4ccccc4C(F)(F)F)cc13)CC2 CHEMBL246852 Ki 949.0 nM
COc1cccc([C@@H](C)NCCCc2ccccc2Cl)c1 CHEMBL2107572 Ki 954.66 nM
CCCN1CCC(COc2nc3scc(C)c3n3cccc23)CC1 CHEMBL470432 pIC50 954.99 nM
c1ccc(-c2ccccc2OC(C2=NCCN2)c2ccccc2)cc1 CHEMBL523048 pKi 954.99 nM
c1ccc(-c2ccccc2NCC2=NCCN2)cc1 CHEMBL337862 pEC50 954.99 nM
CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3F)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1C CHEMBL295395 Ki 955.0 nM
CSc1ccc(C)cc1NCC1=NCCN1 CHEMBL72441 Log Ki 977.24 nM
CN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 CHEMBL422 AC50 979.8 nM
Clc1ccc2c(c1)CCc1cccnc1C2=C1CCNCC1 CHEMBL1172 Ki 980.0 nM
NCCCCCCn1cc(CCCCN2CCC(c3ccc(-c4cc(C(=O)O)cc5cc(-c6ccc(C(F)(F)F)cc6)ccc45)cc3)CC2)nn1 CHEMBL4216870 Ki 984.0 nM
O=C(NCCCNC(=O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O)[C@@H]1[C@H]2C[C@H]3c4[nH]c5ccccc5c4CCN3C[C@@H]2CC[C@@H]1O CHEMBL540594 Ki 990.0 nM
COc1cc2c(cc1OC)C1=NOC(CN3CCN(Cc4ccccc4)CC3)C1CO2 CHEMBL90843 Ki 995.0 nM