Nc1nccc2c1ncn2[C@@H]1C=C(CO)[C@@H](O)[C@H]1O CHEMBL154745 Ki 0.01 nM
C=C(C=O)OC(C=O)n1cnc2c(N)ncnc21 CHEMBL280595 Ki 0.5 nM
Nc1ncc(F)c2c1ncn2[C@@H]1CC[C@@H](O)[C@H]1O CHEMBL3290657 IC50 1.3 nM
Nc1ncnc2c1ncn2[C@@H]1C=C(CO)[C@@H](O)[C@H]1O CHEMBL8771 IC50 1.5 nM
Nc1ncnc2c1ncn2[C@@H]1CC[C@@H](O)[C@H]1O CHEMBL301499 IC50 1.5 nM
Nc1nccn2c([C@@H]3CC[C@@H](O)[C@H]3O)cnc12 CHEMBL3290650 IC50 1.5 nM
CNCCNC(=O)CN(CC(=O)N(C)N1Cc2ccccc2C1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1 CHEMBL3322562 Ki 1.5 nM
Nc1ncc(Cl)c2c1ncn2[C@@H]1CC[C@@H](O)[C@H]1O CHEMBL3290658 IC50 2.2 nM
Nc1ncc(F)c2c1ncn2[C@@H]1C(F)C[C@@H](O)[C@H]1O CHEMBL3290668 IC50 2.7 nM
Nc1ncnc2c1ncn2C(C=O)OC(C=O)CO CHEMBL281476 Ki 3.3 nM
Nc1nccc2c1ncn2[C@@H]1C[C@H](CO)[C@@H](O)[C@H]1O CHEMBL268272 Ki 4.0 nM
Nc1ncnc2c1ncn2[C@H]1[C@H](O)[C@H](O)[C@@H](CO)[C@H]1F CHEMBL2115462 IC50 8.0 nM
CCNCCNC(=O)CN(CC(=O)N(C)N1Cc2ccccc2C1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1 CHEMBL3597832 IC50 8.5 nM
Nc1ncc(F)c2c1ncn2[C@@H]1C[C@H](O)[C@@H](O)[C@H]1O CHEMBL3290663 IC50 9.4 nM
CN(C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)N1Cc2ccccc2C1 CHEMBL3322547 IC50 13.0 nM
Nc1ccnc2c1ncn2[C@@H]1C[C@H](CO)[C@@H](O)[C@H]1O CHEMBL281337 IC50 18.0 nM
C=C[C@H]1C[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL50728 Ki 22.0 nM
C[C@H]1C[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL50306 Ki 27.0 nM
Nc1ncc(F)c2c1ncn2[C@@H]1C=C[C@@H](O)[C@H]1O CHEMBL3290665 IC50 28.0 nM
Nc1nccc2c1ncn2C1C=C(CO)C(O)C1O CHEMBL284846 IC50 31.0 nM
Nc1nccc2c1ncn2C1C=C[C@@H](O)[C@H]1O CHEMBL147260 Ki app 35.0 nM
Cc1cnc(N)c2ncn([C@@H]3CC[C@@H](O)[C@H]3O)c12 CHEMBL3290659 IC50 36.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](C=O)[C@@H](O)[C@H]1O CHEMBL308037 Ki 39.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@@H](C=O)[C@@H](O)[C@H]1O CHEMBL77518 Ki 39.0 nM
Nc1ncnc2c1ncn2[C@@H](C=O)O[C@@H](C=O)CO CHEMBL2374428 IC50 40.0 nM
Nc1ncnc2c1ncn2[C@@H]1C=C[C@@H](O)[C@H]1O CHEMBL299961 Ki app 41.0 nM
Nc1ncc(F)c2c1ncn2[C@@H]1C[C@H](F)[C@@H](O)[C@H]1O CHEMBL3290662 IC50 41.0 nM
COC(=O)N1CCN(N(C)C(=O)CN(CC(=O)NCCN2CCCC2)c2cc(Cl)ccc2Oc2ccc(Cl)cc2)CC1 CHEMBL3322550 IC50 44.0 nM
CC(C)NCCNC(=O)CN(CC(=O)N(C)C1Cc2ccccc2C1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1 CHEMBL3322556 IC50 49.0 nM
CN(C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)N1CCN(S(C)(=O)=O)CC1 CHEMBL3322549 IC50 49.0 nM
CC(C)N(CCNC(=O)CN(CC(=O)N(C)C1Cc2ccccc2C1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C(=O)OC(C)(C)C CHEMBL3597818 IC50 49.0 nM
CN(C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 CHEMBL3322540 IC50 52.0 nM
CCNCCNC(=O)CN(CC(=O)N(C)C1Cc2ccccc2C1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1 CHEMBL3322555 IC50 60.0 nM
CCN(CCNC(=O)CN(CC(=O)N(C)C1Cc2ccccc2C1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C(=O)OC(C)(C)C CHEMBL3597817 IC50 60.0 nM
CNCCNC(=O)CN(CC(=O)N(C)C1Cc2ccccc2C1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1 CHEMBL3322554 IC50 70.0 nM
CN(CCNC(=O)CN(CC(=O)N(C)C1Cc2ccccc2C1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C(=O)OC(C)(C)C CHEMBL3597816 IC50 70.0 nM
C=C1C(CO)C(O)C(O)C1n1cnc2c(N)ncnc21 CHEMBL53931 IC50 80.0 nM
CN(C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1CCc2ccccc2C1 CHEMBL3322541 IC50 81.0 nM
Nc1nccc2c1ncn2C/C=C\[C@@H](O)CO CHEMBL296880 Ki 90.0 nM
CO/N=C/[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL606276 Ki 94.6 nM
Nc1ncnc2c1ncn2C1O[C@H](/C=C/I)[C@@H](O)[C@H]1O CHEMBL608056 Ki 96.0 nM
Nc1nc(F)nc2c1ncn2[C@@H]1CC[C@@H](O)[C@H]1O CHEMBL3290655 IC50 98.0 nM
Nc1ncnc2c1ncn2C1O[C@H](/C=N/OCc2ccccc2)[C@@H](O)[C@H]1O CHEMBL605902 Ki 101.0 nM
Nc1ncnc2c1ncn2CC=C(CO)CO CHEMBL49908 Ki 110.0 nM
Nc1ncnc2c1ncn2[C@@H]1C[C@H](CO)[C@@H](O)[C@H]1O CHEMBL49935 Ki 110.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](/C=C/Cl)[C@@H](O)[C@H]1O CHEMBL2092790 Ki 110.0 nM
CN(C(=O)CN(CC(=O)NC[C@@H]1CCCN1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 CHEMBL3322559 IC50 110.0 nM
CN(C(=O)CN(CC(=O)NC[C@@H]1CCCN1C(=O)OC(C)(C)C)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 CHEMBL3597821 IC50 110.0 nM
CCO/N=C/[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL605900 Ki 111.0 nM
Nc1ncnc2c1ncn2C/C=C\CO CHEMBL45537 Ki 125.0 nM
CN(C)CCNC(=O)CN(CC(=O)N(C)C1Cc2ccccc2C1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1 CHEMBL3322553 IC50 130.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](/C=C/Br)[C@@H](O)[C@H]1O CHEMBL2092789 Ki 134.0 nM
CN(C(=O)CN(CC(=O)NCC1CCCCN1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 CHEMBL3322561 IC50 150.0 nM
CN(C(=O)CN(CC(=O)NCC1CCCCN1C(=O)OC(C)(C)C)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 CHEMBL3597823 IC50 150.0 nM
Nc1ncnc2c1ncn2[C@@H]1C[C@H](O)[C@@H](O)[C@H]1O CHEMBL129014 Ki 160.0 nM
Nc1nccc2c1ncn2CC#CCO CHEMBL49511 Ki 160.0 nM
Nc1nccc2c1ncn2CC=C(CO)CO CHEMBL50600 Ki 166.0 nM
C/C(=C/Cn1cnc2c(N)ncnc21)CO CHEMBL415930 Ki 170.0 nM
Nc1ncnc2c1ncn2[C@H]1[C@H](O)[C@H](O)[C@@H](CO)[C@@H]1F CHEMBL2115031 IC50 180.0 nM
Nc1nc(F)c(F)c2c1ncn2[C@@H]1CC[C@@H](O)[C@H]1O CHEMBL3290660 IC50 189.0 nM
Nc1ncnc2c1ncn2[C@@H]1C=C(CCl)[C@@H](O)[C@H]1O CHEMBL419393 IC50 195.0 nM
Nc1nccc2c1ncn2C/C=C\CO CHEMBL49737 Ki 200.0 nM
Nc1ncnc2c1ncn2C/C=C\[C@@H](O)CO CHEMBL416457 Ki 200.0 nM
CN(C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)N1CCc2ccccc2C1 CHEMBL3322548 IC50 200.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@@H](C=NO)[C@@H](O)[C@H]1O CHEMBL3349025 Ki 224.0 nM
CN(C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1CCN(S(C)(=O)=O)CC1 CHEMBL3322545 IC50 230.0 nM
Nc1ncnc2c1ncn2[C@@H]1C(F)=C(CO)[C@@H](O)[C@H]1O CHEMBL64718 IC50 240.0 nM
Nc1ncnc2c1ncn2[C@@H]1C[C@@H](C=O)[C@@H](O)[C@H]1O CHEMBL77965 Ki 273.0 nM
Nc1ncnc2c1ncn2C[C@H](O)CO CHEMBL494759 IC50 280.0 nM
Nc1ncnc2c1ncn2C1O[C@H](C(=O)OCCCl)[C@@H](O)[C@H]1O CHEMBL610148 Ki 320.0 nM
CN(C(=O)CN(CC(=O)NCCN1CCCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 CHEMBL3322552 IC50 320.0 nM
Nc1ncnc2c1ncn2C/C=C/CO CHEMBL49917 Ki 330.0 nM
CN(C(=O)CN(CC(=O)NCCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 CHEMBL3322551 IC50 330.0 nM
CN(CCc1ccccc1)C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1 CHEMBL3322534 IC50 340.0 nM
Nc1ncnc2c1ncn2C1O[C@H](C(=O)OCc2ccccc2)[C@@H](O)[C@H]1O CHEMBL612224 Ki 360.0 nM
Nc1ncnc2c1ncn2[C@H]1[C@H](O)[C@H](O)[C@@H](CCO)[C@H]1F CHEMBL4638533 IC50 360.0 nM
CNc1ncnc2c1ncn2[C@H]1[C@H](O)[C@H](O)[C@@H](CCO)[C@H]1F CHEMBL4635734 IC50 370.0 nM
CN(C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1CCCCC1 CHEMBL3322533 IC50 380.0 nM
Nc1ncnc2c1ncn2Cc1cc(OCC2CCCCC2)cc(O)c1O CHEMBL1098945 IC50 400.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(=O)O)[C@@H](O)[C@H]1O CHEMBL595547 Ki 410.0 nM
Nc1ncnc2c1ncn2[C@@H]1C=C(CCO)[C@@H](O)[C@H]1O CHEMBL310547 IC50 480.0 nM
C/C(=C\Cn1cnc2c(N)ncnc21)CO CHEMBL295729 Ki 500.0 nM
CN(C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)[C@H]1CC[C@H](c2ccccc2)CC1 CHEMBL3322542 IC50 530.0 nM
CN(Cc1ccccc1)C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1 CHEMBL3322532 IC50 530.0 nM
C#C/C=C/[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL611098 Ki 550.0 nM
CCN(CC)C(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL608072 Ki 570.0 nM
CC(C)COC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL610383 Ki 570.0 nM
CC[C@H]1C[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL296392 Ki 586.0 nM
CN(C(=O)CN(CC(=O)NC[C@H]1CCCN1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 CHEMBL3322560 IC50 600.0 nM
CN(C(=O)CN(CC(=O)NC[C@H]1CCCN1C(=O)OC(C)(C)C)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 CHEMBL3597822 IC50 600.0 nM
CCN(C(=O)CN(CC(=O)NCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 CHEMBL3597813 IC50 640.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](C=NO)[C@@H](O)[C@H]1O CHEMBL1288616 Ki 670.0 nM
Nc1ncnc2c1ncn2[C@H]1O[C@@H](/C=N/O)[C@H](O)[C@@H]1O CHEMBL2364569 Ki 670.0 nM
Nc1ncc(F)c2c1ncn2[C@@H]1C[C@@H](F)[C@@H](O)[C@H]1O CHEMBL3290661 IC50 672.0 nM
C#C[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL604208 Ki 681.0 nM
CCCCOC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL610384 Ki 710.0 nM
CNc1ncnc2c1ncn2[C@H]1[C@H](O)[C@H](O)[C@@H](CO)C1(F)F CHEMBL4538845 IC50 760.0 nM
CC(C)OC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O CHEMBL608915 Ki 770.0 nM
Nc1ncnc2c1ncn2[C@@H]1C=C(CO)C(=O)[C@H]1O CHEMBL2368540 Ki 800.0 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CHEMBL477 Km 820.0 nM
Nc1ncc(F)c2c1ncn2[C@@H]1C[C@@H](O)[C@@H](O)[C@H]1O CHEMBL3290649 IC50 878.0 nM
COC(=O)N1CCC(N(C)C(=O)CN(CC(=O)NCCN2CCCC2)c2cc(Cl)ccc2Oc2ccc(Cl)cc2)CC1 CHEMBL3322546 IC50 890.0 nM
Nc1ncnc2c1ncn2[C@@H]1C(F)=C(CCO)[C@@H](O)[C@H]1O CHEMBL3580900 IC50 910.0 nM
CC(C)=CCn1cnc2c(N)ncnc21 CHEMBL298115 IC50 930.0 nM
Nc1ncnc2c1ncn2C/C=C/C(O)CO CHEMBL296107 IC50 950.0 nM
O=C(CN(CC(=O)N1CCC(c2ccccc2)CC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)NCCN1CCCC1 CHEMBL3322535 IC50 970.0 nM
Nc1ncc(F)c2c1ncn2[C@@H]1C(F)=C[C@@H](O)[C@H]1O CHEMBL3290667 IC50 976.0 nM
Nc1ncnc2c1ncn2CC#CCO CHEMBL46348 IC50 1000.0 nM