c1ccc2c(c1)Nc1nc3ccccc3c3ccnc-2c13 CHEMBL5289699 EC50 0.01 nM
Brc1ccc(-c2nc3ccc(Br)cn3n2)cc1 CHEMBL5203882 EC50 0.03 nM
O=Cc1c2[nH]c3ccccc3c2cc2[nH]c3ccccc3c12 CHEMBL472031 Kd 0.07 nM
Cc1ccc(NC(=O)c2cc3ccccc3n(C)c2=O)cc1 CHEMBL5285977 EC50 0.0971 nM
Cc1cc(Cl)cc2c1oc1cc(Cl)cc(Cl)c12 CHEMBL4580482 Kd 0.13 nM
C[C@@H]1CCCc2c1cc(C(=O)Nc1ccccc1)c(=O)n2C CHEMBL5270440 EC50 0.137 nM
C[C@H]1CCCc2c1cc(C(=O)Nc1ccccc1)c(=O)n2C CHEMBL5266782 EC50 0.161 nM
C[C@@H]1CCc2c1cc(C(=O)Nc1cc3ccccc3[nH]1)c(=O)n2C CHEMBL5265853 EC50 0.189 nM
c1ccc2c(c1)[nH]c1cc3c(cc12)[nH]c1ccccc13 CHEMBL509307 Kd 0.19 nM
O=C1Nc2ccccc2/C1=C1/Nc2ccccc2C1=O CHEMBL1276127 EC50 0.2 nM
FC(F)(F)c1ccc(/C=C/c2cc(Cl)cc(Cl)c2)cc1 CHEMBL179510 Ki 0.2 nM
Cn1c(=O)c(C(=O)Nc2ccc(F)cc2)cc2ccccc21 CHEMBL5271031 EC50 0.214 nM
Cn1c2ccccc2c2cc3[nH]c4ccccc4c3c(C=O)c21 CHEMBL4646273 EC50 0.26 nM
[O-][n+]1c(-c2ccc(Br)cc2)nc2ccc(Br)cn21 CHEMBL5190861 EC50 0.27 nM
C[C@H]1CCc2c(cc(C(=O)Nc3ccccc3)c(=O)n2C)C1 CHEMBL5284079 EC50 0.275 nM
C[C@@H]1Cc2cc(C(=O)Nc3ccccc3)c(=O)n(C)c2C1 CHEMBL5274394 EC50 0.297 nM
COc1ccc(NC(=O)c2cc3ccccc3n(C)c2=O)cc1 CHEMBL5280290 EC50 0.304 nM
[O-][n+]1c(-c2ccc(Br)cc2)nc2ccc(Cl)cn21 CHEMBL5021347 EC50 0.34 nM
CC1CCc2c1cc(C(=O)Nc1ncc(F)s1)c(=O)n2C CHEMBL5270280 EC50 0.34 nM
Cn1c(=O)c(C(=O)Nc2ccc(F)cn2)cc2ccccc21 CHEMBL5275365 EC50 0.389 nM
FC(F)(F)c1ccc(-c2nc3ccc(Br)cn3n2)cc1 CHEMBL5194336 EC50 0.44 nM
Clc1cc2c(cc1Br)Oc1cc(Br)c(Cl)cc1O2 CHEMBL137408 pEC50 0.4467 nM
Cn1c(=O)c(C(=O)Nc2ccc(F)cc2)cc2cccnc21 CHEMBL5267272 EC50 0.468 nM
O=C(Nc1ccc(F)cc1)c1cc2cccc3c2n(c1=O)CC3 CHEMBL5269910 EC50 0.511 nM
O=C1c2cc(Br)c(Cl)cc2C[C@H]2c3ccccc3CCN12 CHEMBL5186309 EC50 0.7 nM
Clc1ccc(-c2nc3ccc(Br)cn3n2)cc1 CHEMBL5181725 EC50 0.83 nM
C[C@@H](CO)NC(=O)c1cc(-c2ccc(OC(F)(F)F)cc2)nc(-c2cccnc2)n1 CHEMBL5281742 IC50 0.885 nM
Brc1ccc2c(c1)Oc1cc(Br)c(Br)cc1O2 CHEMBL136453 pEC50 1.169 nM
O=C(c1cccc(C(F)(F)F)n1)c1c[nH]c2ccccc12 CHEMBL4750416 EC50 1.2 nM
Clc1cc2c(cc1Cl)Oc1cc(Br)c(Br)cc1O2 CHEMBL136430 pEC50 1.479 nM
Brc1cc2c(cc1Br)Oc1cc(Br)c(Br)cc1O2 CHEMBL341968 pEC50 1.5 nM
CNC(=O)c1csc(C(=O)c2c[nH]c3ccccc23)n1 CHEMBL5198290 EC50 1.6 nM
Brc1cc(Br)c2c(c1)Oc1cc(Br)c(Br)cc1O2 CHEMBL137055 pEC50 2.0 nM
N#Cc1cccc(C(=O)c2c[nH]c3ccccc23)n1 CHEMBL4764225 EC50 2.0 nM
O=c1c2cccc3cccc(c32)c2nc3ccc(Cl)cc3n12 CHEMBL4536502 IC50 2.6 nM
c1ccc2c(c1)cc1ccc3cccc4ccc2c1c34 CHEMBL31184 EC50 5.0 nM
O=C1/C(=C2\Nc3ccccc3C2=O)Nc2ccccc21 CHEMBL599552 EC50 5.0 nM
Brc1cc2c(cc1Br)Oc1c(cc(Br)c(Br)c1Br)O2 CHEMBL137665 pEC50 6.607 nM
O=c1cc(-c2ccccc2)oc2ccc3ccccc3c12 CHEMBL26260 EC50 8.4 nM
Clc1cc2c(cc1Cl)Oc1cc(Cl)c(Cl)cc1O2 CHEMBL30327 EC50 9.0 nM
Brc1cccc(-c2nc3ccc(Br)cn3n2)c1 CHEMBL5199691 EC50 9.6 nM
Clc1cc2c(cc1Cl)Oc1cc(Br)c(Cl)cc1O2 CHEMBL138223 pEC50 11.51 nM
COc1ccc(/C=C\c2cc(Cl)cc(Cl)c2)cc1 CHEMBL178967 Ki(app) 12.0 nM
CCCCOc1ccc(/C=C\c2cc(OC)cc(OC)c2)cc1 CHEMBL426049 Ki(app) 12.0 nM
CCOc1ccc(/C=C\c2cc(OC)cc(OC)c2)cc1 CHEMBL179243 Ki(app) 12.0 nM
Clc1ccc(/C=C\c2cc(Cl)cc(Cl)c2)cc1 CHEMBL361413 Ki(app) 12.0 nM
COc1ccc(/C=C\c2cc(OC)cc(OC)c2)cc1 CHEMBL311636 Ki(app) 12.0 nM
O=c1c(Cc2c[nH]c3ccccc23)nccc2c1[nH]c1ccccc12 CHEMBL5267667 EC50 12.0 nM
C#CCN1C(=O)/C(=C/c2n[nH]c3ccccc23)NC1=S CHEMBL5410096 EC50 15.0 nM
Clc1cc2oc3c(Cl)c(Cl)c(Cl)cc3c2cc1Cl CHEMBL335558 pEC50 15.14 nM
Brc1ccc2c(c1)Oc1ccc(Br)cc1O2 CHEMBL135555 pEC50 15.49 nM
Brc1cc2c(cc1Br)Oc1c(Br)c(Br)cc(Br)c1O2 CHEMBL422101 pEC50 16.98 nM
CSc1ncc(C(=O)Nc2ccc(Cl)cc2)c(C)n1 CHEMBL1520832 EC50 22.2 nM
N#Cc1ccc2nc(-c3ccc(Br)cc3)nn2c1 CHEMBL5198934 EC50 23.0 nM
COc1ccc(-c2nc3cc(F)ccc3s2)cc1OC CHEMBL373251 IC50 25.0 nM
Clc1ccc2c(c1)oc1c(Cl)c(Cl)c(Cl)cc12 CHEMBL336463 pEC50 25.12 nM
CC(C)c1c(O)cc(/C=C/c2ccccc2)cc1O CHEMBL259571 EC50 27.0 nM
O=c1c(O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12 CHEMBL150 IC50 28.0 nM
Cc1ccccc1/N=N/c1ccc(NC(=O)c2ccnn2C)c(C)c1 CHEMBL1743245 IC50 30.0 nM
OCc1csc(C(O)c2c[nH]c3ccccc23)n1 CHEMBL5185943 EC50 32.0 nM
C=CCN1C(=O)/C(=C/c2n[nH]c3ccccc23)NC1=S CHEMBL5418753 EC50 35.0 nM
CC(CO)NC(=O)c1cc(-c2ccc(Cl)cc2)nn(-c2cccc(F)c2)c1=O CHEMBL5266911 IC50 39.9 nM
Clc1cc2oc3cc(Cl)c(Cl)cc3c2cc1Cl CHEMBL136710 pEC50 41.02 nM
Clc1cc2c(oc3c(Cl)c(Cl)c(Cl)cc32)c(Cl)c1Cl CHEMBL343049 pEC50 46.77 nM
CN1C(=O)/C(=C/c2n[nH]c3ccccc23)NC1=S CHEMBL5419477 EC50 49.0 nM
CCS(=O)(=O)c1ccc2oc(-c3ccc4ccccc4c3)nc2c1 CHEMBL1773683 Kd 50.0 nM
O=C1/C(=C/c2n[nH]c3ccccc23)NC(=S)N1C1CC1 CHEMBL5406192 EC50 52.0 nM
Cn1cc(Cc2[nH]c3ccccc3c2C=O)c2ccccc21 CHEMBL3319501 EC50 55.0 nM
[O-][n+]1c(-c2ccc(Br)cc2)nc2cc(Br)ccn21 CHEMBL5195426 EC50 62.0 nM
Clc1ccc2c(oc3c(Cl)cc(Cl)c(Cl)c32)c1Cl CHEMBL136782 pEC50 67.76 nM
COc1ccccc1NC(=O)c1ccc(C(=O)Nc2ccccc2OC)nc1 CHEMBL1462325 EC50 68.63 nM
Clc1ccc2c(c1)Oc1cc(Cl)c(Cl)cc1O2 CHEMBL136335 pEC50 70.96 nM
Clc1cc2oc3cc(Cl)c(Cl)c(Cl)c3c2cc1Cl CHEMBL137304 pEC50 74.13 nM
N#Cc1ccc2nc(-c3ccc(Br)cc3)[n+]([O-])n2c1 CHEMBL5183442 EC50 77.0 nM
Clc1cc2c(cc1Cl)Oc1c(cc(Cl)c(Cl)c1Cl)O2 CHEMBL137220 pEC50 79.43 nM
O=C(NCC(O)C(F)(F)F)c1cc(-c2ccc(OC(F)(F)F)cc2)nn(-c2cccnc2)c1=O CHEMBL5271453 IC50 82.2 nM
[O-][n+]1c(-c2ccc(Br)cc2)nc2cc(F)ccn21 CHEMBL5207451 EC50 83.0 nM
Cn1cc(Cc2cc3ccccc3[nH]2)c2ccccc21 CHEMBL3319505 EC50 86.0 nM
c1ccc2c(Cc3c[nH]c4ccccc34)c[nH]c2c1 CHEMBL446452 Kd 90.0 nM
Brc1cc(Br)c2c(c1)Oc1cc(Br)cc(Br)c1O2 CHEMBL135026 pEC50 92.9 nM
O=Cc1c(Cc2c[nH]c3ccc(Cl)cc23)[nH]c2ccccc12 CHEMBL3319498 EC50 93.0 nM
COc1ccc2[nH]cc(Cc3cc4ccccc4[nH]3)c2c1 CHEMBL3319504 EC50 94.0 nM
COc1ccc(Cn2cc(C(=O)c3nccs3)c3ccccc32)cc1 CHEMBL5179114 EC50 110.0 nM
Cc1cc(Nc2ccc(Br)cc2)n2nc(C)nc2n1 CHEMBL597452 EC50 116.66 nM
Clc1ccc2oc3c(Cl)c(Cl)c(Cl)c(Cl)c3c2c1 CHEMBL344919 pEC50 119.95 nM
CC(C)n1cnc2c(NCCc3ccc(O)cc3)nc(-c3csc4ccccc34)nc21 CHEMBL4303221 IC50 127.0 nM
Clc1ccc(-c2cc(Cl)c(Cl)c(Cl)c2)cc1Cl CHEMBL342696 pEC50 130.02 nM
CN1C(=O)/C(=C/c2c[nH]c3ccccc23)NC1=S CHEMBL5439352 EC50 143.0 nM
Clc1ccc2nc(-c3ccc(Br)cc3)nn2c1 CHEMBL5173018 EC50 156.0 nM
Clc1cc2c(cc1Cl)Oc1c(ccc(Cl)c1Cl)O2 CHEMBL137849 pEC50 159.96 nM
CC(=O)O/N=C1C(=C2/C(=O)Nc3cc(Br)ccc32)/Nc2ccccc2/1 CHEMBL430226 EC50 160.0 nM
O=C1NC(=S)N/C1=C\c1n[nH]c2ccccc12 CHEMBL5434388 EC50 163.0 nM
Brc1ccc(-c2nc3c(Br)cccn3n2)cc1 CHEMBL5203209 EC50 172.0 nM
COc1ccccc1NC(=O)c1ccc2c(c1)nnn2C CHEMBL1372374 EC50 195.21 nM
Clc1cc(Cl)c2c(c1)oc1c(Cl)c(Cl)c(Cl)cc12 CHEMBL334374 pEC50 199.99 nM
Clc1cc2oc3c(Cl)c(Cl)cc(Cl)c3c2cc1Cl CHEMBL342648 pEC50 199.99 nM
Clc1ccc2oc3c(Cl)c(Cl)c(Cl)cc3c2c1 CHEMBL137477 pEC50 199.99 nM
O=c1cc(-c2c(F)cccc2F)oc2ccc3ccccc3c12 CHEMBL600169 EC50 200.0 nM
[O-][n+]1c(-c2ccc(Br)cc2)nc2cccc(Br)n21 CHEMBL5194855 EC50 205.0 nM
c1ccc2[nH]c(Cc3c[nH]c4ccccc34)cc2c1 CHEMBL3319502 EC50 215.0 nM
CCN1C(=O)/C(=C/c2n[nH]c3ccccc23)NC1=S CHEMBL5416301 EC50 219.0 nM
Clc1ccc2c(c1)oc1cc(Cl)c(Cl)c(Cl)c12 CHEMBL136729 pEC50 219.28 nM
Clc1cc(Cl)c2oc3cc(Cl)c(Cl)cc3c2c1 CHEMBL136882 pEC50 219.79 nM
Clc1cc2c(cc1Cl)Oc1c(Cl)cccc1O2 CHEMBL136184 pEC50 219.79 nM
COc1ccc2[nH]cc(Cc3[nH]c4ccccc4c3C=O)c2c1 CHEMBL3319500 EC50 230.0 nM
Clc1cc2oc3c(Cl)c(Cl)c(Cl)c(Cl)c3c2cc1Cl CHEMBL342717 pEC50 230.14 nM
NS(=O)(=O)c1ccc(-c2ccc(/C=C3\SC(=O)NC3=O)o2)cc1 CHEMBL232148 EC50 237.15 nM
Clc1cc2c(oc3cc(Cl)c(Cl)c(Cl)c32)c(Cl)c1Cl CHEMBL343494 pEC50 269.77 nM
COc1ccccc1-c1cc(=O)c2c(ccc3ccccc32)o1 CHEMBL599550 EC50 270.0 nM
O=Cc1c(Cc2c[nH]c3ccccc23)[nH]c2ccccc12 CHEMBL3319497 EC50 270.0 nM
[O-][n+]1c(-c2ccc(Br)cc2)nc2cc(Cl)ccn21 CHEMBL5195658 EC50 271.0 nM
Clc1cc2c(cc1Cl)Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1O2 CHEMBL136116 pEC50 279.9 nM
Nc1cc2c3c(cccc3c1)C(=O)N(CCN1CCCC1)C2=O CHEMBL1487460 EC50 286.1 nM
Brc1ccc2c(c1)Oc1ccccc1O2 CHEMBL139414 pEC50 295.12 nM
O=C(O)c1cc(=O)c2ccccc2[nH]1 CHEMBL299155 EC50 300.0 nM
O=Cc1c(Cc2c[nH]c3c(Cl)cccc23)[nH]c2ccccc12 CHEMBL3319499 EC50 320.0 nM
O=c1cc(-c2ccccc2F)oc2ccc3ccccc3c12 CHEMBL599338 EC50 330.0 nM
Clc1cc2c(oc3c(Cl)cccc32)c(Cl)c1Cl CHEMBL136843 pEC50 349.95 nM
Clc1cc2oc3c(Cl)cccc3c2c(Cl)c1Cl CHEMBL134683 pEC50 349.95 nM
Cc1nc(N)nc(Nc2ccc(Cl)cc2)c1Br CHEMBL1430231 EC50 350.94 nM
NNc1nc(O)c2c3c(sc2n1)-c1ccccc1CC3 CHEMBL1516375 EC50 373.01 nM
[O-][n+]1c(-c2ccc(Br)cc2)nc2c(Br)cccn21 CHEMBL5208085 EC50 374.0 nM
COc1cc2ccccc2cc1C(=O)Nc1ccc(C)cc1 CHEMBL1509929 EC50 393.66 nM
Clc1cc(Cl)c2c(c1)oc1cc(Cl)c(Cl)c(Cl)c12 CHEMBL134370 pEC50 399.94 nM
Clc1ccc2oc3c(Cl)c(Cl)ccc3c2c1 CHEMBL334874 pEC50 449.78 nM
O=c1cc(-c2ccccn2)oc2ccc3ccccc3c12 CHEMBL599551 EC50 450.0 nM
CCCC(=O)Nc1nn(C)c2nc3cc(C)ccc3cc12 CHEMBL1529540 EC50 458.05 nM
Cc1ccc2cc3c(NC(=O)CC(C)C)nn(C)c3nc2c1 CHEMBL1506957 EC50 476.31 nM
CN1CCN(CCCNC(=O)c2cc3c(-c4ccc(Cl)cc4)nn(C)c3s2)CC1 CHEMBL1544647 EC50 482.93 nM
Cc1ccc2cc3c(ccc4ccccc43)c3c2c1CC3 CHEMBL40583 EC50 490.0 nM
CC#CCN1C(=O)/C(=C/c2n[nH]c3ccccc23)NC1=S CHEMBL5399322 EC50 528.0 nM
C#CCn1cc(/C=N/NC(=O)c2cc3ccccc3o2)c2ccccc21 CHEMBL3193884 EC50 544.01 nM
O=C(Nc1cccc(Cl)c1)c1cccnn1 CHEMBL1551329 EC50 583.2 nM
CN1C(=O)/C(=C/c2cc3ccccc3[nH]2)NC1=S CHEMBL5419189 EC50 613.0 nM
Brc1ccc(-c2nc3cccc(Br)n3n2)cc1 CHEMBL5207284 EC50 625.0 nM
Brc1ccc(-c2nc3cc(Br)ccn3n2)cc1 CHEMBL5197557 EC50 625.0 nM
COc1cccc(-c2nc3ccccc3c(=S)[nH]2)c1 CHEMBL3823873 EC50 630.0 nM
Fc1ccc2nc(-c3ccc(Br)cc3)nn2c1 CHEMBL5196574 EC50 658.0 nM
Clc1ccc(-c2ccc(Cl)c(Cl)c2)cc1Cl CHEMBL344161 pEC50 709.58 nM
Cc1nnc(N2C(=O)c3cccc4c([N+](=O)[O-])ccc(c34)C2=O)s1 CHEMBL1533640 EC50 733.46 nM
[O-][n+]1c(-c2ccc(Br)cc2)nc2ccc(C(F)(F)F)cn21 CHEMBL5172120 EC50 759.0 nM
Clc1cc(Cl)c2c(c1)Oc1cc(Cl)c(Cl)cc1O2 CHEMBL136222 pEC50 794.33 nM
CN(C)CCCN1C(=O)c2cccc3cccc(c23)C1=O CHEMBL295786 EC50 814.96 nM
Cc1ccc2nc(-c3ccc(Br)cc3)[n+]([O-])n2c1 CHEMBL5206725 EC50 842.0 nM
CN(C)c1nc(N)nc(-c2nc3ccccc3s2)n1 CHEMBL1386446 EC50 844.89 nM
Cn1c(N)c(C(=O)Nc2ccccc2F)sc1=S CHEMBL1557667 EC50 856.5 nM
CN1C(=O)/C(=C/c2cn(C)c3ccccc23)NC1=S CHEMBL5426272 EC50 858.0 nM
O=C(NC(=S)Nc1ccc(F)c(Cl)c1)C1CC1 CHEMBL1488455 EC50 860.52 nM
Cn1c(C(=O)N2CCC(C(N)=O)CC2)cc2cc(Cl)ccc21 CHEMBL1383935 EC50 910.0 nM
COc1ccc(NC(=O)c2cccc3c(Br)cccc23)cc1 CHEMBL1413196 EC50 965.0 nM
Cc1cc(C)n2cc(-c3ccc(Cl)cc3)c(C(=O)O)c2n1 CHEMBL1393674 EC50 994.0 nM
Clc1ccc2oc3cc(Cl)c(Cl)cc3c2c1 CHEMBL136844 pEC50 1000.0 nM
CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)n1ccnc1 CHEMBL522782 EC50 1000.0 nM