O=C(O)CN1C(=O)S/C(=C/c2cccc([N+](=O)[O-])c2)C1=O CHEMBL2260162 IC50 0.13 nM
O=C1NC(=O)/C(=C\c2cccc(O)c2)S1 CHEMBL2260155 IC50 0.15 nM
O=C(O)CN1C(=O)S/C(=C\c2ccc(Oc3ccccc3)cc2)C1=O CHEMBL1645381 IC50 0.17 nM
COC(=O)CN1C(=O)S/C(=C/c2cccc(Oc3ccccc3)c2)C1=O CHEMBL2260152 IC50 0.26 nM
O=C1NC(=O)/C(=C/c2cccc(Oc3ccccc3)c2)S1 CHEMBL1645384 IC50 0.28 nM
O=C(O)CN1C(=O)S/C(=C/c2ccc(O)cc2)C1=O CHEMBL2260158 IC50 0.49 nM
O=C(O)CN1C(=O)S/C(=C/c2ccc(-c3ccccc3)cc2)C1=O CHEMBL2260153 IC50 0.66 nM
O=C(O)CN1C(=O)S/C(=C/c2ccc([N+](=O)[O-])cc2)C1=O CHEMBL2260163 IC50 0.82 nM
Cc1c(S(=O)(=O)c2ccc(=O)[nH]n2)oc2ccc(Cl)cc12 CHEMBL240725 IC50 0.84 nM
O=C(O)Cc1nn(Cc2nc3cccc(Cl)c3s2)c(=O)c2ccccc12 CHEMBL20207 IC50 1.0 nM
O=C(O)/C=C/CN1C(=O)S/C(=C/c2ccc(O)cc2)C1=O CHEMBL2260159 IC50 1.19 nM
COC(=O)CN1C(=O)S/C(=C/c2cccc(N)c2)C1=O CHEMBL2260161 IC50 1.32 nM
O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c(=O)c2ccccc12 CHEMBL10372 IC50 1.9 nM
O=C(O)Cc1nn(Cc2nc3c(F)cccc3s2)c(=O)c2ccccc12 CHEMBL20024 IC50 2.0 nM
O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c(=O)c2ncccc12 CHEMBL69956 IC50 2.1 nM
Cc1c(S(=O)(=O)c2ccc(O)nn2)oc2ccc(F)cc12 CHEMBL198096 IC50 3.0 nM
O=C(O)Cc1nn(Cc2nc3cc(Br)ccc3s2)c(=O)c2ccccc12 CHEMBL20169 IC50 3.1 nM
O=C(O)Cc1nn(Cc2nc3ccc(C(F)(F)F)cc3s2)c(=O)c2ccccc12 CHEMBL20740 IC50 3.1 nM
O=C(O)Cc1nn(Cc2nc3cc(F)cc(F)c3o2)c(=O)c2ccccc12 CHEMBL143234 IC50 3.2 nM
Cc1c(CC(=O)O)nn(Cc2nc3cc(F)cc(F)c3s2)c(=O)c1C CHEMBL73560 IC50 3.2 nM
Cc1c(CC(=O)O)nn(Cc2nc(-c3cccc(F)c3F)no2)c(=O)c1C CHEMBL71966 IC50 3.3 nM
O=C(O)Cc1nn(Cc2nc3c(Cl)cccc3s2)c(=O)c2ccccc12 CHEMBL20015 IC50 3.5 nM
O=C(O)Cc1nn(Cc2nc3cc(F)cc(F)c3s2)c(=O)c2c1CCCC2 CHEMBL304995 IC50 4.0 nM
O=C(O)Cc1nn(Cc2nc3cc(Cl)cc(Cl)c3s2)c(=O)c2ccccc12 CHEMBL278991 IC50 4.0 nM
O=C(O)CN1C(=O)S/C(=C/c2cccc(O)c2)C1=O CHEMBL2260156 IC50 4.17 nM
O=C(O)Cc1nn(Cc2nc3cc(F)ccc3s2)c2ccc(Cl)cc12 CHEMBL73505 IC50 4.6 nM
O=C(O)Cc1nn(Cc2nc3c(F)ccc(F)c3s2)c(=O)c2ccccc12 CHEMBL282689 IC50 5.0 nM
O=C(O)Cc1nn(Cc2nc3cc(Cl)cc(F)c3s2)c(=O)c2ccccc12 CHEMBL20518 IC50 5.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2ccccc21 CHEMBL363387 IC50 5.0 nM
COc1ccc2c(Cc3nc4c(F)c(F)cc(F)c4s3)cn(CC(=O)O)c2c1 CHEMBL190931 IC50 5.0 nM
Cc1c(S(=O)(=O)c2ccc(O)nn2)oc2ccc(C(F)(F)F)cc12 CHEMBL370123 IC50 5.0 nM
O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c(=O)c2c1CCCC2 CHEMBL68580 IC50 5.2 nM
Cc1cc(C)c2sc(Cn3nc(CC(=O)O)c4ccccc4c3=O)nc2c1 CHEMBL20161 IC50 5.9 nM
Cc1cccc2c(Cc3nc4c(F)c(F)cc(F)c4s3)cn(CC(=O)O)c12 CHEMBL192886 IC50 6.0 nM
CCc1c(S(=O)(=O)c2ccc(O)nn2)oc2ccc(Cl)cc12 CHEMBL440567 IC50 6.0 nM
O=C(O)COc1cc(Cl)ccc1C(=O)NCc1cccc([N+](=O)[O-])c1 CHEMBL241577 IC50 6.0 nM
O=C(O)COc1cc(F)ccc1C(=S)NCc1cccc([N+](=O)[O-])c1 CHEMBL5286261 IC50 6.0 nM
Nc1cccc(/C=C2/SC(=O)NC2=O)c1 CHEMBL2260160 IC50 6.14 nM
O=C(O)CN1C(=O)S/C(=C/c2cccc3ccccc23)C1=O CHEMBL2260154 IC50 6.18 nM
O=C(O)Cc1nn(Cc2nc3cc(F)cc(Cl)c3s2)c(=O)c2ccccc12 CHEMBL416001 IC50 6.2 nM
O=C(O)CN1C(=O)/C(=C/c2cccc(OCCc3ccccc3)c2)SC1=S CHEMBL4459307 Ki 6.2 nM
O=C(O)Cc1nn(Cc2nc3cc(F)cc(F)c3s2)c(=O)c2ccccc12 CHEMBL20637 IC50 6.3 nM
Cc1ccccc1-c1noc(Cn2nc(CC(=O)O)c3ccccc3c2=O)n1 CHEMBL422647 IC50 6.4 nM
O=C(O)Cc1nn(Cc2nc(-c3ccccc3Br)no2)c(=O)c2ccccc12 CHEMBL341864 IC50 6.5 nM
COc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)NC(C)C)cc1 CHEMBL2440411 IC50 6.7 nM
O=C(O)Cc1nn(Cc2nc3cc(F)ccc3s2)c(=O)c2ccccc12 CHEMBL283996 IC50 6.9 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2ccc(F)cc21 CHEMBL371991 IC50 7.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cccc(F)c21 CHEMBL192167 IC50 7.0 nM
N#Cc1cc(C(=O)NCc2cccc([N+](=O)[O-])c2)c(OCC(=O)O)cc1F CHEMBL241367 IC50 7.0 nM
O=C(O)Cc1nn(Cc2nc3cc(Cl)ccc3s2)c(=O)c2ccccc12 CHEMBL20197 IC50 7.1 nM
C[C@@H]1C[C@]2(NC(=O)NC2=O)c2cc(Cl)cnc2O1 CHEMBL56453 IC50 7.5 nM
Cc1c(Cc2nc3c(F)c(F)cc(F)c3s2)c2ccccc2n1CC(=O)O CHEMBL364235 IC50 8.0 nM
Cc1ccc2c(c1)c(Cc1nc3c(F)c(F)cc(F)c3s1)cn2CC(=O)O CHEMBL191508 IC50 8.0 nM
COc1ccc2c(c1)c(Cc1nc3c(F)c(F)cc(F)c3s1)cn2CC(=O)O CHEMBL192255 IC50 8.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cc(N3CCOCC3)ccc21 CHEMBL370478 IC50 8.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2ccc(Cl)cc21 CHEMBL371162 IC50 8.0 nM
O=C(O)Cn1cc(CCc2nc3c(F)c(F)cc(F)c3s2)c2ccccc21 CHEMBL193155 IC50 8.0 nM
O=C(O)Cn1c(=O)n(Cc2ccc(Br)cc2F)c(=O)c2ccc(Cl)cc21 CHEMBL10413 IC50 8.0 nM
O=C1NC(=O)/C(=C/c2cccc3ccccc23)S1 CHEMBL1348329 IC50 8.96 nM
NC(=O)[C@@H]1C[C@]2(NC(=O)NC2=O)c2cc(F)ccc2O1 CHEMBL84446 IC50 9.0 nM
O=C(O)Cn1cc(Cc2nc3cc(F)ccc3s2)c2ccccc21 CHEMBL193569 IC50 9.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cccc(Cl)c21 CHEMBL189801 IC50 9.0 nM
CC(/C=C1\SC(=S)N(CC(=O)O)C1=O)=C\c1ccccc1 CHEMBL56337 IC50 10.0 nM
O=C(O)Cc1nn(Cc2nc3cccc(C(F)(F)F)c3s2)c(=O)c2ccccc12 CHEMBL20220 IC50 10.0 nM
O=C(O)Cc1nn(Cc2nc3c(F)c(F)ccc3s2)c(=O)c2ccccc12 CHEMBL422927 IC50 10.0 nM
O=C(O)Cc1nn(Cc2nc3cccnc3s2)c(=O)c2ccccc12 CHEMBL19289 IC50 10.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2cc(Cl)c(Cl)cc12 CHEMBL19958 IC50 10.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cc(Cl)ccc21 CHEMBL192263 IC50 10.0 nM
Cc1ccc2c(Cc3nc4c(F)c(F)cc(F)c4s3)cn(CC(=O)O)c2c1 CHEMBL192927 IC50 10.0 nM
O=CC(O)CO CHEMBL173813 IC50 10.0 nM
COc1ccc2c(C(=S)N(C)CC(=O)O)cccc2c1C(F)(F)F CHEMBL436 IC50 10.0 nM
O=C(O)CN1C(=O)S/C(=C\c2ccc(OCc3ccccc3)cc2)C1=O CHEMBL1645382 IC50 10.7 nM
O=C(O)CN1C(=O)S/C(=C\c2cccc(Oc3ccccc3)c2)C1=O CHEMBL1645380 IC50 10.7 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2c(Cl)cccc21 CHEMBL193277 IC50 11.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cc(F)ccc21 CHEMBL193254 IC50 11.0 nM
O=C(O)COc1cc(F)ccc1C(=O)NCc1nc2c(F)c(F)cc(F)c2s1 CHEMBL399598 IC50 11.0 nM
COc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)Nc2ccccn2)cc1 CHEMBL1172665 IC50 11.0 nM
O=C1NC(=O)C2(N1)c1cc(F)ccc1-c1c(-c3cn(C4CCCC4)nn3)cc(F)cc12 CHEMBL5418720 IC50 11.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2cc(C(F)(F)F)ccc12 CHEMBL20693 IC50 12.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2ccc(Br)cc12 CHEMBL416370 IC50 12.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(F)c(Cl)cc2O1 CHEMBL303218 IC50 12.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cc(OCc3ccccc3)ccc21 CHEMBL192399 IC50 12.0 nM
O=C(Nc1ccccn1)c1cc2ccc(O)cc2o/c1=N\c1ccc(I)cc1 CHEMBL2440426 IC50 12.0 nM
O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1ccc(F)cc12 CHEMBL273910 IC50 12.2 nM
O=C(O)Cc1nn(CC(=O)Nc2cccc(Cl)c2)c(=O)c2ccccc12 CHEMBL143633 IC50 13.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cc(Br)ccc21 CHEMBL192434 IC50 13.0 nM
Cc1ccc2oc(S(=O)(=O)c3ccc(O)nn3)c(C)c2c1 CHEMBL198148 IC50 13.0 nM
O=C1NC(=O)C2(N1)c1ccc(OCCO)cc1-c1ccc(F)cc12 CHEMBL5421140 IC50 13.0 nM
O=C(/C=C/c1ccc(O)c(O)c1)OC[C@@H]1O[C@H](Oc2c(-c3ccc(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)[C@@H](O)[C@H](O)[C@H]1O CHEMBL2263318 IC50 13.4 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cccc(Br)c21 CHEMBL193030 IC50 14.0 nM
O=C1NC(=O)C2(N1)c1cc(F)ccc1-c1cc(OC3COC3)c(F)cc12 CHEMBL5431713 IC50 14.0 nM
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL50 IC50 14.8 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2cc(Cl)ccc12 CHEMBL20796 IC50 15.0 nM
O=C(O)Cc1nn(Cc2nc3cccc(Br)c3s2)c(=O)c2ccccc12 CHEMBL21038 IC50 15.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2ccc(N3CCOCC3)cc21 CHEMBL192762 IC50 15.0 nM
O=C1C[C@@]2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1cccn12 CHEMBL334830 IC50 15.0 nM
COc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)NCCCc2cccc(O)c2)cc1 CHEMBL4089816 IC50 15.0 nM
O=C(O)Cc1cc(F)cc2c1-c1ccc(F)cc1C21NC(=O)NC1=O CHEMBL5431549 IC50 15.0 nM
O=C1NC(=O)C2(N1)c1cc(F)ccc1-c1cc(C3CC3)c(F)cc12 CHEMBL5400501 IC50 15.0 nM
Cc1c(CC(=O)O)nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c(=O)c1C CHEMBL69350 IC50 16.0 nM
O=C(O)CN1C(=O)S/C(=C\c2cccc(OCCc3ccccc3)c2)C1=O CHEMBL4448571 Ki 16.0 nM
O=C1NC(=O)C2(N1)c1cc(F)ccc1-c1c(F)cccc12 CHEMBL5400147 IC50 16.0 nM
COc1ccc2c(c1)-c1ccc(F)cc1C21NC(=O)NC1=O CHEMBL5414059 IC50 16.0 nM
O=C1NC(=O)C2(N1)c1ccccc1-c1ccc(Cl)cc12 CHEMBL5438141 IC50 16.0 nM
O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)cc(F)c3s2)c(=O)c2ccccc12 CHEMBL19701 IC50 17.0 nM
O=C(O)CCn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2ccccc21 CHEMBL193839 IC50 17.0 nM
Cc1cc(=O)n(Cc2nc3cc(C(F)(F)F)ccc3s2)nc1CC(=O)O CHEMBL303210 IC50 18.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2ccc(C(F)(F)F)cc12 CHEMBL283787 IC50 18.0 nM
O=C1NC(=O)C2(N1)c1cc(F)ccc1-c1c(OCC(=O)N3CCC3)cc(F)cc12 CHEMBL5414200 IC50 18.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2ccccc12 CHEMBL21091 IC50 19.0 nM
O=C(O)Cc1nn(CC(=O)Nc2cccc(C(F)(F)F)c2)c(=O)c2ccccc12 CHEMBL344057 IC50 19.0 nM
O=C(O)Cc1nn(Cc2nc(-c3cccc(F)c3F)no2)c(=O)c2ccccc12 CHEMBL143098 IC50 19.0 nM
O=C(O)c1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)Nc2ccccn2)cc1 CHEMBL2440423 IC50 19.0 nM
O=C1NC(=O)C2(N1)c1ccc(OCC(=O)N3CCC3)cc1-c1ccc(F)cc12 CHEMBL5413369 IC50 19.0 nM
O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1ccccc12 CHEMBL62685 IC50 19.4 nM
O=C(O)Cc1nn(Cc2nc3c(Cl)ccc(Cl)c3s2)c(=O)c2ccccc12 CHEMBL282263 IC50 20.0 nM
COc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)NCCO)cc1 CHEMBL2440415 IC50 20.0 nM
O=C(O)Cc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)Nc2ccccn2)cc1 CHEMBL2440427 IC50 20.0 nM
O=C(O)Cc1nn(Cc2cc(F)cc(Br)c2)c(=O)c2ccccc12 CHEMBL4436968 IC50 20.0 nM
O=C1NC(=O)/C(=C/c2ccc(O)cc2)S1 CHEMBL87706 IC50 20.2 nM
O=C(O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c2ccccc12 CHEMBL7679 IC50 21.0 nM
COc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)Nc2ccccn2)c(OC)c1 CHEMBL1171546 IC50 21.0 nM
CN1C(=O)Nc2ccc(Cl)cc2[C@@]12NC(=O)NC2=O CHEMBL292723 IC50 22.0 nM
O=C(O)Cc1nn(CC(=O)Nc2cccc(F)c2)c(=O)c2ccccc12 CHEMBL139666 IC50 22.0 nM
O=C1NC(=O)C2(N1)c1cc(F)ccc1-c1ccc(Br)cc12 CHEMBL5417323 IC50 22.0 nM
O=C(O)COc1cc2c(cc1F)C1(NC(=O)NC1=O)c1cc(F)ccc1-2 CHEMBL5399554 IC50 22.0 nM
O=C(O)Cc1nn(Cc2nc(-c3ccccc3Cl)no2)c(=O)c2ccccc12 CHEMBL345068 IC50 23.0 nM
O=S(=O)(c1ccc(O)nn1)c1oc2ccccc2c1-c1ccccc1 CHEMBL197878 IC50 23.0 nM
COc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)NCc2ccccc2)cc1 CHEMBL2440417 IC50 24.0 nM
O=C(Nc1ccccn1)c1cc2ccc(O)cc2o/c1=N\c1ccc(O)cc1 CHEMBL2440422 IC50 24.0 nM
O=c1ccc(S(=O)(=O)c2cc3ccccc3o2)n[nH]1 CHEMBL241777 IC50 25.0 nM
O=C(O)Cc1nn(Cc2nc3c(C(F)(F)F)cccc3s2)c(=O)c2ccccc12 CHEMBL280168 IC50 25.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2ccc(-c3ccccc3)cc21 CHEMBL195065 IC50 25.0 nM
O=c1ccc(S(=O)(=O)c2cc3cc(Cl)ccc3o2)n[nH]1 CHEMBL240722 IC50 25.0 nM
O=C(Nc1ccccn1)c1cc2ccc(O)cc2o/c1=N\c1ccc(Br)cc1 CHEMBL2440425 IC50 25.0 nM
O=C(O)CN1C(=O)/C(=C/c2cccc(Oc3ccccc3)c2)SC1=S CHEMBL1172417 IC50 25.0 nM
O=C(O)Cc1nn(Cc2nc3cc(F)cc(F)c3s2)c(=O)c2cccnc12 CHEMBL305064 IC50 26.0 nM
COc1ccc2c(CC(=O)O)nn(Cc3nc4ccccc4s3)c(=O)c2c1 CHEMBL19906 IC50 26.0 nM
Cc1ccc2sc(Cn3nc(CC(=O)O)c4ccccc4c3=O)nc2c1 CHEMBL19966 IC50 26.0 nM
O=C(O)Cc1nn(Cc2nc3ccc(Br)cc3s2)c(=O)c2ccccc12 CHEMBL20004 IC50 26.0 nM
CC(c1nc2cc(Cl)ccc2s1)n1nc(CC(=O)O)c2ccccc2c1=O CHEMBL20009 IC50 26.0 nM
O=S(=O)(Cc1c(F)cccc1Cl)c1ccc(O)nn1 CHEMBL371307 IC50 26.0 nM
Cc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)Nc2ccccn2)cc1 CHEMBL2440424 IC50 26.0 nM
O=C(O)Cc1nn(Cc2nc3cc(Br)ccc3o2)c(=O)c2ccccc12 CHEMBL358792 IC50 27.0 nM
Cc1ccc2c(=O)n(Cc3nc4ccccc4s3)nc(CC(=O)O)c2c1 CHEMBL284018 IC50 27.0 nM
COc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)NC2CCCCC2)cc1 CHEMBL2440414 IC50 27.0 nM
O=C1NC(=O)C2(N1)c1cc(F)ccc1-c1ccc(F)cc12 CHEMBL269455 IC50 27.0 nM
O=C(O)Cc1nn(Cc2noc(-c3ccccc3Cl)n2)c(=O)c2ccccc12 CHEMBL2111988 IC50 28.0 nM
O=C(O)Cc1nn(CC(=O)Nc2cc(C(F)(F)F)ccc2Br)c(=O)c2ccccc12 CHEMBL142599 IC50 28.0 nM
COc1ccc2c(=O)n(Cc3nc4ccccc4s3)nc(CC(=O)O)c2c1 CHEMBL19759 IC50 28.0 nM
COc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)NCC(C)C)cc1 CHEMBL2440413 IC50 28.0 nM
CCCCNC(=O)c1cc2ccc(O)cc2o/c1=N\c1ccc(OC)cc1 CHEMBL2440412 IC50 28.0 nM
O=C(O)COc1cc(F)ccc1C(=O)NCc1nc2cc(C(F)(F)F)ccc2s1 CHEMBL240721 IC50 29.0 nM
COc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)NCCCO)cc1 CHEMBL2440416 IC50 29.0 nM
O=C1NC(=O)C(c2cc(Cl)ccc2S(=O)(=O)NCc2ccccc2)N1 CHEMBL19187 IC50 30.0 nM
O=C(O)Cc1nn(Cc2nc3cc(F)cc(F)c3s2)c2ccccc12 CHEMBL308216 IC50 30.0 nM
Cc1cc2c(cc1Cl)C1(NC(=O)NC1=O)N(C)C(=O)N2 CHEMBL63974 IC50 30.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2c(F)cccc12 CHEMBL20440 IC50 30.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cc(Oc3ccccc3)ccc21 CHEMBL363850 IC50 30.0 nM
O=C(O)COc1cc(F)ccc1C(=S)NCc1ccc(Br)cc1F CHEMBL395347 IC50 30.0 nM
O=C(O)COc1cc(Cl)ccc1C(=O)NCc1ccc(Br)cc1F CHEMBL1230062 IC50 30.0 nM
O=C(O)CN1C(=O)/C(=C/c2cccc(OCCCCc3ccccc3)c2)SC1=S CHEMBL5428185 Ki 30.0 nM
O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3o2)c(=O)c2ccccc12 CHEMBL142989 IC50 31.0 nM
O=C(O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c2c1CCCC2 CHEMBL66006 IC50 32.0 nM
O=C(O)Cc1nn(Cc2nc3cc(Cl)cc(Cl)c3o2)c(=O)c2ccccc12 CHEMBL142790 IC50 32.0 nM
O=C(O)Cc1c(O)c(F)cc2c1-c1ccc(F)cc1C21NC(=O)NC1=O CHEMBL5397238 IC50 32.0 nM
O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c2ccccc12 CHEMBL306244 IC50 33.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2cc([N+](=O)[O-])ccc12 CHEMBL20116 IC50 33.0 nM
O=C(O)Cc1nn(Cc2nc(-c3ccccc3)cs2)c(=O)c2ccccc12 CHEMBL140199 IC50 34.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2ccc(Cl)cc12 CHEMBL20005 IC50 34.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)cccc3s2)c2ccccc21 CHEMBL372902 IC50 34.0 nM
O=S(=O)(c1ccc(O)nn1)c1oc2ccc(Cl)cc2c1-c1ccccc1 CHEMBL425920 IC50 34.0 nM
COc1ccc(/N=c2\oc3cc(O)ccc3cc2C(=O)Nc2cccc(C)n2)cc1OC CHEMBL1169757 IC50 34.0 nM
O=C(Nc1ccccn1)c1cc2ccc(O)cc2o/c1=N\c1ccccc1 CHEMBL2440428 IC50 34.0 nM
O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c2ccc(Cl)cc12 CHEMBL68705 IC50 35.0 nM
O=S(=O)(Cc1cccc(Cl)c1Cl)c1ccc(O)nn1 CHEMBL197805 IC50 35.0 nM
O=C(O)COc1cc(Cl)ccc1C(=O)NCc1nc2cc(C(F)(F)F)ccc2s1 CHEMBL240720 IC50 35.0 nM
COc1ccc(OC)c(/N=c2\oc3cc(O)ccc3cc2C(=O)Nc2ccccn2)c1 CHEMBL1169756 IC50 36.0 nM
CN1C(=O)Nc2c(Cl)cc(Cl)cc2C12NC(=O)NC2=O CHEMBL416870 IC50 37.0 nM
O=C(O)Cc1nn(Cc2cn3ccc(Cl)cc3n2)c(=O)c2ccccc12 CHEMBL344526 IC50 37.0 nM
CC(c1nc2cc(C(F)(F)F)ccc2s1)n1nc(CC(=O)O)c2ccccc2c1=O CHEMBL283151 IC50 37.0 nM
O=C1NC(=O)C2(CN(Cc3nc4ccccc4s3)c3ccc(Cl)cc32)N1 CHEMBL20685 IC50 37.0 nM
COC(=O)CN1C(=O)S/C(=C/c2ccc(O)cc2)C1=O CHEMBL2260157 IC50 39.1 nM
COc1cc(/C=C2\SC(=S)N(CC(=O)O)C2=O)ccc1OCc1ccccc1 CHEMBL4554837 IC50 40.0 nM
O=C(O)CNC(=O)c1ccc(N2C(=O)/C(=C/c3cn(-c4ccccc4)nc3-c3cccc(F)c3)SC2=S)cc1 CHEMBL5273049 IC50 40.0 nM
O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c(=O)c2cccnc12 CHEMBL309132 IC50 41.0 nM
O=C(O)Cc1nn(Cc2nc3cc(O)ccc3s2)c(=O)c2ccccc12 CHEMBL417643 IC50 41.0 nM
CN1C(=O)Nc2c(F)cccc2C12NC(=O)NC2=O CHEMBL303779 IC50 42.0 nM
Cc1cccc2c(CC(=O)O)nn(Cc3nc4c(ccc5ccccc54)s3)c(=O)c12 CHEMBL20304 IC50 42.0 nM
CC(c1nc2ccccc2s1)n1nc(CC(=O)O)c2ccccc2c1=O CHEMBL282017 IC50 43.0 nM
O=S(=O)(Cc1cccc(C(F)(F)F)c1F)c1ccc(O)nn1 CHEMBL446704 IC50 44.0 nM
O=C1NC(=O)C2(N1)c1cc(F)ccc1-c1ccc(C3CCC3)cc12 CHEMBL5396251 IC50 44.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2cc3ccccc3cc12 CHEMBL69537 IC50 46.0 nM
CN1C(=O)Nc2c([N+](=O)[O-])cc(Cl)cc2C12NC(=O)NC2=O CHEMBL66476 IC50 46.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2ccc([N+](=O)[O-])cc12 CHEMBL278522 IC50 46.0 nM
O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c(=O)c2cc3ccccc3cc12 CHEMBL4458061 IC50 46.0 nM
O=S(=O)(c1ccc(O)nn1)c1oc2ccccc2c1-c1ccc(F)cc1 CHEMBL372136 IC50 49.0 nM
CS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL277520 IC50 50.0 nM
CCCCCS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL19427 IC50 50.0 nM
O=C(O)Cc1nn(C/C(S)=N/c2cccc(Cl)c2)c(=O)c2ccccc12 CHEMBL140012 IC50 50.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(Cl)c(Br)cc2O1 CHEMBL304302 IC50 50.0 nM
O=S(=O)(c1ccc(O)nn1)c1c(Cl)cccc1Cl CHEMBL197712 IC50 50.0 nM
O=C(O)CN1C(=O)/C(=C/c2cccc(OCCCc3ccccc3)c2)SC1=S CHEMBL5421281 IC50 50.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(Cl)c(Cl)cc2O1 CHEMBL70014 IC50 50.9 nM
CN1C(=O)Nc2ccc(Br)cc2C12NC(=O)NC2=O CHEMBL303058 IC50 52.0 nM
O=C(O)Cc1nn(C/C(S)=N/c2cccc(C(F)(F)F)c2)c(=O)c2ccccc12 CHEMBL140750 IC50 52.0 nM
O=C(O)Cn1cc(Cc2nc3cc(C(F)(F)F)ccc3s2)c2ccc(Br)cc21 CHEMBL191570 IC50 52.0 nM
O=S(=O)(Cc1c(Cl)cccc1Cl)c1ccc(O)nn1 CHEMBL372641 IC50 52.0 nM
O=C(O)CN1C(=O)/C(=C/c2ccc(OCc3ccccc3)cc2)SC1=S CHEMBL185623 IC50 52.0 nM
O=C1NC(=O)C2(N1)c1ccccc1-c1c(F)cccc12 CHEMBL5397588 IC50 52.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cc(-c3ccccc3)ccc21 CHEMBL192182 IC50 53.0 nM
O=C(O)CN1C(=O)/C(=C/c2cccc(OCc3ccccc3)c2)SC1=S CHEMBL184768 IC50 53.0 nM
O=C(O)COc1ccc2c(c1)-c1ccc(F)cc1C21NC(=O)NC1=O CHEMBL5400944 IC50 53.0 nM
O=S(=O)(Cc1cccc(Cl)c1F)c1ccc(O)nn1 CHEMBL198250 IC50 54.0 nM
O=C(O)Cn1cc(Cc2nc3cccc(F)c3s2)c2ccccc21 CHEMBL364313 IC50 55.0 nM
O=S(=O)(c1ccc(O)nn1)c1cccc(Cl)c1Cl CHEMBL198764 IC50 55.0 nM
Cc1c(S(=O)(=O)c2ccc(O)nn2)sc2ccc(Cl)cc12 CHEMBL371914 IC50 55.0 nM
O=C(O)Cn1c2c(c3cc(C(=O)O)ccc31)CCN(Cc1ccccc1)C2=S CHEMBL1944862 Kis 55.0 nM
CN1C(=O)Nc2ccc(Cl)cc2C12NC(=O)NC2=O CHEMBL65372 IC50 56.0 nM
O=C1NC(=O)C2(N1)c1cc(Cl)ccc1-c1ccc(Cl)cc12 CHEMBL5420064 IC50 56.0 nM
O=C(O)Cn1c2ccccc2c2nnc(S)nc21 CHEMBL1405739 IC50 57.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c2ccc(Cl)cc12 CHEMBL67591 IC50 58.0 nM
COc1cc2c(cc1Cl)C1(NC(=O)NC1=O)N(C)C(=O)N2 CHEMBL65385 IC50 59.0 nM
CSc1ccc2sc(Cn3nc(CC(=O)O)c4ccccc4c3=O)nc2c1 CHEMBL418007 IC50 60.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(Cl)c(OCc3ccccc3)cc2O1 CHEMBL69938 IC50 60.0 nM
O=C(O)CN1C(=O)/C(=C/c2ccc(Oc3ccccc3)cc2)SC1=S CHEMBL1645387 IC50 60.0 nM
Cc1cccc(-c2nn(-c3ccccc3)cc2/C=C2\SC(=S)N(c3ccc(C(=O)NCC(=O)O)cc3)C2=O)c1 CHEMBL5271166 IC50 60.0 nM
Cc1c(S(=O)(=O)c2ccc(Cl)cc2)c2c(NS(C)(=O)=O)cccc2n1CC(=O)O CHEMBL1917450 IC50 63.0 nM
CN1C(=O)Nc2ccc(F)cc2[C@@]12NC(=O)NC2=O CHEMBL63778 IC50 64.0 nM
NC(=O)COc1cccc(/C=C2\SC(=S)N(CC(=O)O)C2=O)c1 CHEMBL3262475 IC50 64.0 nM
O=C(O)Cc1nn(Cc2nc3cc(Br)ccc3s2)c2ccc(Cl)cc12 CHEMBL421487 IC50 65.0 nM
O=C(O)Cn1c2ccccc2c2n[nH]c(=O)nc21 CHEMBL4582264 IC50 66.0 nM
CCOC(=O)N1CCc2c(c3cc(OC)ccc3n2CC(=O)O)C1 CHEMBL4206601 Ki 66.1 nM
O=C1NC(=O)[C@@]2(CCOc3ccc(F)cc32)N1 CHEMBL266497 IC50 67.0 nM
O=C(O)Cc1nn(Cc2nc3cc(F)c(F)cc3s2)c(=O)c2ccccc12 CHEMBL20306 IC50 68.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc([N+](=O)[O-])c(F)cc2O1 CHEMBL69769 IC50 70.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2ccc(C(=O)O)cc2O1 CHEMBL70190 IC50 70.0 nM
COc1c(Cl)cc2c(c1Cl)NC(=O)N(C)C21NC(=O)NC1=O CHEMBL292998 IC50 72.0 nM
O=S(=O)(Cc1cccc(C(F)(F)F)c1)c1ccc(O)nn1 CHEMBL433987 IC50 72.0 nM
O=C1C[C@@]2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1ccc(F)cc12 CHEMBL292963 IC50 72.6 nM
CN1C(=O)Nc2ccc([N+](=O)[O-])cc2C12NC(=O)NC2=O CHEMBL63429 IC50 73.0 nM
O=S(=O)(c1ccc(O)nn1)c1cc(Cl)ccc1Cl CHEMBL371901 IC50 73.0 nM
CN1C(=O)c2ccc(F)cc2C2(CC(=O)NC2=O)C1=O CHEMBL10615 IC50 73.2 nM
CN1C(=O)Nc2cc(Cl)c(Cl)cc2C12NC(=O)NC2=O CHEMBL303362 IC50 74.0 nM
O=C(O)Cc1nn(Cc2nc3ccc(Cl)cc3s2)c(=O)c2ccccc12 CHEMBL20581 IC50 76.0 nM
O=C(O)Cc1nn(Cc2nc3cc(Cl)ccc3o2)c(=O)c2ccccc12 CHEMBL143211 IC50 78.0 nM
O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H]1[C@H](O)C[C@@](O)(C(=O)O)C[C@H]1OC(=O)/C=C/c1ccc(O)c(O)c1 CHEMBL249448 IC50 78.0 nM
COc1cccc(/C=C2\SC(=S)N(CC(=O)O)C2=O)c1 CHEMBL1645388 IC50 78.0 nM
CN1C(=O)c2ccc(Cl)cc2C2(CC(=O)NC2=O)C1=O CHEMBL10382 IC50 78.2 nM
COc1ccc2c(c1)c1c(n2CC(=O)O)C(=S)N(Cc2ccccc2)CC1 CHEMBL1944855 Kis 79.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc([N+](=O)[O-])ccc2O1 CHEMBL69546 IC50 80.0 nM
O=C(O)CN1C(=O)/C(=C/c2cccc(OCCCOc3ccccc3)c2)SC1=S CHEMBL5415620 IC50 80.0 nM
O=C(O)Cc1nn(CSc2nc3ccccc3s2)c(=O)c2ccccc12 CHEMBL281407 IC50 81.0 nM
O=C(O)Cc1nn(Cc2nc3cc(O)cc(O)c3s2)c(=O)c2ccccc12 CHEMBL21136 IC50 87.0 nM
O=c1ccc(S(=O)(=O)c2cc3cc(Cl)cc(Cl)c3o2)n[nH]1 CHEMBL239440 IC50 87.0 nM
O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H]1C[C@](O)(C(=O)O)C[C@@H](OC(=O)/C=C/c2ccc(O)c(O)c2)[C@H]1O CHEMBL249447 IC50 88.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3o2)c(=O)c2ccccc12 CHEMBL142274 IC50 89.0 nM
Cc1cc2c(cc1[N+](=O)[O-])[C@](O)(CC(=O)O)C[C@@H](C)O2 CHEMBL302804 IC50 90.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(F)c(Br)cc2O1 CHEMBL68963 IC50 90.0 nM
CC(C)c1c(S(=O)(=O)c2ccc(O)nn2)oc2ccc(Cl)cc12 CHEMBL372193 IC50 92.0 nM
CN1C(=O)Nc2cc(Cl)ccc2C12NC(=O)NC2=O CHEMBL291854 IC50 94.0 nM
O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)cc(Cl)c3s2)c(=O)c2ccccc12 CHEMBL19893 IC50 94.0 nM
O=C(NCCc1ccc(O)cc1)c1cc2ccc(O)cc2oc1=O CHEMBL3318218 IC50 98.0 nM
O=C(O)Cn1cc(Cc2nc3cc(C(F)(F)F)ccc3s2)c2ccccc21 CHEMBL410917 IC50 99.0 nM
O=C1NC(=O)C(c2cc(Cl)ccc2S(=O)(=O)NCCCc2ccccc2)N1 CHEMBL19711 IC50 100.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3o2)c2ccc(Cl)cc12 CHEMBL69907 IC50 100.0 nM
CN1C(=O)Nc2ccc(F)cc2C12NC(=O)NC2=O CHEMBL66588 IC50 100.0 nM
O=C(O)Cc1nn(Cc2nc3c(O)cccc3s2)c(=O)c2ccccc12 CHEMBL20441 IC50 100.0 nM
COc1cccc2sc(Cn3nc(CC(=O)O)c4ccccc4c3=O)nc12 CHEMBL19373 IC50 100.0 nM
O=C(O)Cc1nn(Cc2nc3cc(F)cc(C(F)(F)F)c3s2)c(=O)c2ccccc12 CHEMBL20115 IC50 100.0 nM
O=C(O)Cc1nn(Cc2nc3c(Cl)c(Cl)ccc3s2)c(=O)c2ccccc12 CHEMBL283364 IC50 100.0 nM
CCc1cc2c(cc1Cl)[C@](O)(CC(=O)O)C[C@@H](C)O2 CHEMBL305985 IC50 100.0 nM
Cc1ccc2c(c1)c(Cc1nc3cc(C(F)(F)F)ccc3s1)cn2CC(=O)O CHEMBL192453 IC50 100.0 nM
O=C(O)Cn1c(-c2ccccc2)c(Cc2nc3c(F)c(F)cc(F)c3s2)c2ccccc21 CHEMBL364699 IC50 100.0 nM
CC1=N/C(=C\c2ccc3ccccc3c2)C(=O)N1CC(=O)O CHEMBL3964987 IC50 100.0 nM
O=C(O)CN1C(=O)/C(=C/c2ccc(OCCc3ccccc3)cc2)SC1=S CHEMBL4436037 IC50 104.0 nM
N#Cc1ccc(CNC(=O)c2ccc(Cl)cc2OCC(=O)O)cc1[N+](=O)[O-] CHEMBL5288197 Ki 107.0 nM
Cc1ccccc1CC(=O)Nc1cc(C)c(S(=O)(=O)NCC(=O)O)c(C)c1 CHEMBL240719 IC50 108.0 nM
O=C(O)Cc1nn(Cc2nc3cc(F)cc(F)c3s2)c2ccc(Cl)cc12 CHEMBL419254 IC50 110.0 nM
O=C(O)Cc1nn(Cc2cc3c(Cl)cccc3s2)c(=O)c2ccccc12 CHEMBL142879 IC50 110.0 nM
O=C(O)Cc1nn(Cc2nc3cc(Cl)c(F)cc3s2)c(=O)c2ccccc12 CHEMBL20253 IC50 110.0 nM
CC(C)c1ccc2c(CC(=O)O)nn(Cc3nc4ccccc4s3)c(=O)c2c1 CHEMBL282435 IC50 110.0 nM
CC(C)c1ccc2c(=O)n(Cc3nc4ccccc4s3)nc(CC(=O)O)c2c1 CHEMBL277928 IC50 110.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc([N+](=O)[O-])c(Cl)cc2O1 CHEMBL303474 IC50 110.0 nM
COc1cccc(S(=O)(=O)c2c(C)n(CC(=O)O)c3ccc(C)cc23)c1 CHEMBL1917448 IC50 115.0 nM
O=S(=O)(Cc1ccccc1Cl)c1ccc(O)nn1 CHEMBL373040 IC50 118.0 nM
CN1C(=O)Nc2cc(Cl)c([N+](=O)[O-])cc2C12NC(=O)NC2=O CHEMBL66637 IC50 120.0 nM
O=C(O)Cc1nn(Cc2cc3ccccc3s2)c(=O)c2ccccc12 CHEMBL342339 IC50 120.0 nM
O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)c(O)cc3s2)c(=O)c2ccccc12 CHEMBL20884 IC50 120.0 nM
O=C(O)CN1C(=O)/C(=C/C=C/c2ccccc2)SC1=S CHEMBL1384494 IC50 125.0 nM
CNS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL19744 IC50 130.0 nM
C[C@@H]1C[C@]2(NC(=O)NC2=O)c2cc(Cl)c[n+]([O-])c2O1 CHEMBL56424 IC50 130.0 nM
CN1C(=O)Nc2c(N)cc(Cl)cc2C12NC(=O)NC2=O CHEMBL65181 IC50 130.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(C#N)c(F)cc2O1 CHEMBL441254 IC50 130.0 nM
O=C(O)Cn1cc(Cc2nc3cc(C(F)(F)F)ccc3s2)c2cc(Cl)ccc21 CHEMBL371122 IC50 130.0 nM
CC1=N/C(=C\c2cc(C)c(O)c(C)c2)C(=O)N1CC(=O)O CHEMBL3956034 IC50 130.0 nM
COc1ccc(/C=C2\SC(=S)N(CC(=O)O)C2=O)cc1OCC(N)=O CHEMBL3262477 IC50 139.0 nM
O=S(=O)(c1ccc(O)nn1)c1ccc(Br)cc1F CHEMBL307279 IC50 140.0 nM
CN1C(=O)Nc2c(cc(F)c(F)c2F)C12NC(=O)NC2=O CHEMBL63640 IC50 140.0 nM
O=C1NC(=O)C2(CN(Cc3ccc(F)cc3)c3ccc(F)cc32)N1 CHEMBL281620 IC50 140.0 nM
Cc1c(S(=O)(=O)c2ccc(O)nn2)oc2ccccc12 CHEMBL198331 IC50 140.0 nM
O=C(O)/C=C/c1ccc(O)cc1 CHEMBL66879 IC50 140.0 nM
O=C1CC2(C(=O)N1)C(=O)N(Cc1nc3cc(C(F)(F)F)ccc3s1)C(=O)c1ccc(F)cc12 CHEMBL10552 IC50 144.1 nM
NS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL279878 IC50 150.0 nM
O=S(=O)(c1ccc(O)nn1)c1cc2ccccc2s1 CHEMBL73415 IC50 150.0 nM
O=C(O)Cc1nn(Cc2cc3cc(F)ccc3s2)c(=O)c2ccccc12 CHEMBL357460 IC50 150.0 nM
O=C(O)Cc1nn(Cc2cc3cc(Cl)ccc3o2)c(=O)c2ccccc12 CHEMBL143551 IC50 150.0 nM
Cc1cc2c(C(C)C)c(O)c(O)c3c2c(c1-c1c(C)cc2c(C(C)C)c(O)c(O)c4c2c1OC4=O)OC3=O CHEMBL110030 Ki 150.0 nM
O=S(=O)(c1ccc(O)nn1)c1cccc2ccccc12 CHEMBL194582 IC50 150.0 nM
C[C@@H]1O[C@@H](Oc2c(-c3ccc(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)[C@H](O)[C@H](O)[C@H]1O CHEMBL82242 IC50 150.0 nM
O=C(O)CN1C(=O)S/C(=C\c2ccc(O)cc2)C1=O CHEMBL486917 IC50 150.0 nM
CN1C(=O)N(Cc2cc(Cl)ccc2F)C(=O)[C@]12C(=O)N(CC(=O)O)c1ccc(Cl)cc12 CHEMBL2042239 IC50 150.0 nM
O=C(O)Cc1nn(Cc2nc(-c3ccccn3)no2)c(=O)c2ccccc12 CHEMBL357206 IC50 156.0 nM
O=C(O)Cc1nn(Cc2nc(-c3ccccc3)no2)c(=O)c2ccccc12 CHEMBL143231 IC50 160.0 nM
Cc1ccc2sc(S(=O)(=O)c3ccc(O)nn3)cc2c1 CHEMBL197841 IC50 160.0 nM
CC(C(=O)O)n1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2ccccc21 CHEMBL193307 IC50 163.0 nM
O=S(=O)(c1ccc(O)nn1)c1ccccc1Cl CHEMBL72699 IC50 170.0 nM
O=C(O)Cc1nn(CC(=O)Nc2cc(F)cc(F)c2O)c(=O)c2ccccc12 CHEMBL143863 IC50 170.0 nM
O=C(O)Cc1nn(Cc2nc3c(Cl)cc(Cl)cc3s2)c(=O)c2ccccc12 CHEMBL20575 IC50 170.0 nM
CCCS(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 CHEMBL1917584 IC50 172.0 nM
O=S(=O)(c1cccc(C(F)(F)F)c1)c1ccc(O)nn1 CHEMBL194905 IC50 175.0 nM
O=C(O)COc1ccccc1C(=O)NCc1ccc(Br)cc1F CHEMBL241572 IC50 176.0 nM
CCS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL19495 IC50 180.0 nM
O=C(NCCCc1cccc(O)c1)c1cc2ccc(O)cc2oc1=O CHEMBL4071421 IC50 180.0 nM
CCCCCNS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL19532 IC50 190.0 nM
O=S(=O)(c1ccc(O)nn1)c1ccc(Cl)cc1Cl CHEMBL74183 IC50 190.0 nM
COc1cc2c(cc1Cl)[C@](O)(CC(=O)O)C[C@@H](C)O2 CHEMBL68992 IC50 190.0 nM
Cc1c(S(=O)(=O)c2ccc(O)nn2)oc2cc(Cl)ccc12 CHEMBL199100 IC50 190.0 nM
O=C1C[C@]2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1cccn12 CHEMBL335776 IC50 190.0 nM
O=C(O)Cn1c2c(c3cc(I)ccc31)CCN(Cc1ccccc1)C2=S CHEMBL1944854 IC50 190.0 nM
O=C(O)Cn1c2c(c3c(Cl)cc(Cl)cc31)CCN(Cc1ccccc1)C2=S CHEMBL1944857 IC50 190.0 nM
C/C(=N\NC(=S)Nc1cccc(F)c1)c1ccc2c(c1)NC(=O)CO2 CHEMBL4782682 IC50 190.0 nM
O=C(O)COc1cc(Cl)ccc1C(=O)NCc1ccc(I)cc1F CHEMBL5267913 IC50 190.0 nM
NC(=O)COc1ccc(/C=C2\SC(=S)N(CC(=O)O)C2=O)cc1 CHEMBL3262476 IC50 194.0 nM
O=C(O)Cc1nn(CC(=O)Nc2cc(C(F)(F)F)ccc2O)c(=O)c2ccccc12 CHEMBL342974 IC50 200.0 nM
O=C(O)Cc1nn(C/C(S)=N/c2cc(C(F)(F)F)ccc2Br)c(=O)c2ccccc12 CHEMBL141013 IC50 200.0 nM
CCOC(=O)C1=C(O)C(=O)N(Cc2ccncc2)C1 CHEMBL266773 IC50 200.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(F)ccc2O1 CHEMBL71701 IC50 200.0 nM
O=S(=O)(c1ccc(O)nn1)c1cc2cc(Cl)cc(Cl)c2[nH]1 CHEMBL370444 IC50 200.0 nM
O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23 CHEMBL6246 IC50 200.0 nM
CC(C)c1ccc2c(c1)c1c(n2CC(=O)O)C(=S)N(Cc2ccccc2)CC1 CHEMBL1944856 IC50 200.0 nM
O=C(O)Cn1c2c(c3cc(O)ccc31)CCN(Cc1ccccc1)C2=S CHEMBL1944861 IC50 200.0 nM
Cc1ccc(CCCNC(=O)c2cc3ccc(O)cc3oc2=O)cc1 CHEMBL4062779 IC50 200.0 nM
O=C(NCCCc1ccc(O)cc1)c1cc2ccc(O)cc2oc1=O CHEMBL4081954 IC50 204.0 nM
O=S(=O)(c1ccc(O)nn1)c1ccccc1Br CHEMBL74579 IC50 210.0 nM
CC(C(=O)O)c1cc(O)c2c(c1)CCc1ccccc1C2=O CHEMBL77692 IC50 210.0 nM
O=C1NC(=O)C2(N1)c1cc(F)ccc1-c1ccc(C3CC3)cc12 CHEMBL5423635 IC50 212.0 nM
O=C1NC(=O)C(c2cc(Cl)ccc2S(=O)(=O)CCc2ccc(Cl)cc2)N1 CHEMBL19316 IC50 220.0 nM
Cc1ccc2c(c1)NC(=O)N(C)C21NC(=O)NC1=O CHEMBL65659 IC50 220.0 nM
O=C(O)Cc1nn(Cc2nc(-c3ccccc3C(F)(F)F)no2)c(=O)c2ccccc12 CHEMBL141390 IC50 220.0 nM
O=C(COc1cc(O)c2c(=O)cc(-c3ccccc3)oc2c1)OCc1cccc(OCc2c(-c3ccccc3)no[n+]2[O-])c1 CHEMBL1668044 IC50 220.0 nM
O=C(O)Cn1c2c(c3ccccc31)CCN(Cc1ccccc1)C2=S CHEMBL1946959 IC50 220.0 nM
O=C(NCCCc1ccccc1O)c1cc2ccc(O)cc2oc1=O CHEMBL4098452 IC50 220.0 nM
O=C(O)CN1C(=O)/C(=C/c2ccc(OCCCOc3ccccc3)cc2)SC1=S CHEMBL5413872 IC50 220.0 nM
O=C(O)CC1C(=O)N(Cc2ccc(Br)cc2F)C(=O)c2ccc(F)cc21 CHEMBL10350 IC50 226.6 nM
COc1cc(/C=C2\SC(=S)N(CC(=O)O)C2=O)ccc1OCC(N)=O CHEMBL3262478 IC50 228.0 nM
CCCCCCS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL18854 IC50 230.0 nM
O=C1NC(=O)C(c2cc(Cl)ccc2S(=O)(=O)Nc2ccc(F)cc2)N1 CHEMBL274727 IC50 230.0 nM
COc1ccc2sc(Cn3nc(CC(=O)O)c4ccccc4c3=O)nc2c1 CHEMBL19873 IC50 230.0 nM
COc1ccc2oc(S(=O)(=O)c3ccc(=O)[nH]n3)cc2c1 CHEMBL241570 IC50 230.0 nM
O=C(O)Cn1c2c(c3cc(F)ccc31)CCN(Cc1ccccc1)C2=S CHEMBL1946960 IC50 230.0 nM
CCOC(=O)c1ccc2c(c1)C1(NC(=O)NC1=O)N(C)C(=O)N2 CHEMBL304257 IC50 240.0 nM
O=C(O)Cc1nn(Cc2nc(-c3c(F)cccc3Cl)no2)c(=O)c2ccccc12 CHEMBL143241 IC50 240.0 nM
CCOC(=O)C1=C(O)C(=O)N(Cc2ccc(Cl)c(Cl)c2)C1 CHEMBL7415 IC50 240.0 nM
Cc1cc2c(cc1Cl)[C@](O)(CC(=O)O)C[C@@H](C)O2 CHEMBL69689 IC50 240.0 nM
O=S(=O)(c1cccc(Cl)c1)c1ccc(O)nn1 CHEMBL197924 IC50 240.0 nM
O=C(O)Cn1c2c(c3ccc(Cl)cc31)CCN(Cc1ccccc1)C2=S CHEMBL1946966 IC50 240.0 nM
CC1=N/C(=C\c2ccc(Br)cc2)C(=O)N1CC(=O)O CHEMBL3935367 IC50 240.0 nM
CCCS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL443492 IC50 250.0 nM
C[S+]([O-])c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL279274 IC50 250.0 nM
O=C(O)Cc1nn(Cc2cc3cc(Cl)ccc3s2)c(=O)c2ccccc12 CHEMBL141135 IC50 250.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(F)c(F)cc2O1 CHEMBL71820 IC50 250.0 nM
O=S(=O)(Cc1cccc(F)c1F)c1ccc(O)nn1 CHEMBL197806 IC50 257.0 nM
CN1C(=O)Nc2c([N+](=O)[O-])cc([N+](=O)[O-])cc2C12NC(=O)NC2=O CHEMBL65731 IC50 260.0 nM
CCOC(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1 CHEMBL269550 IC50 260.0 nM
O=C(O)CN1C(=O)/C(=C/c2ccc(OCCCc3ccccc3)cc2)SC1=S CHEMBL5404287 IC50 260.0 nM
O=C1NC(=O)C(c2cc(Cl)ccc2S(=O)(=O)Cc2ccc(Cl)cc2)N1 CHEMBL19649 IC50 270.0 nM
Cc1cc(Cl)cc(C2NC(=O)NC2=O)c1S(C)(=O)=O CHEMBL19502 IC50 270.0 nM
CC1=N/C(=C\c2ccc(Cl)cc2)C(=O)N1CC(=O)O CHEMBL3942794 IC50 270.0 nM
O=C(NCCCc1ccc(F)cc1)c1cc2ccc(O)cc2oc1=O CHEMBL4089817 IC50 277.0 nM
O=S(=O)(c1ccc(O)nn1)c1ccc(F)cc1Cl CHEMBL73491 IC50 280.0 nM
CN1C(=O)Nc2ccccc2C12NC(=O)NC2=O CHEMBL65870 IC50 280.0 nM
COc1ccc(Sc2c(C)n(CC(=O)O)c3ccc(C)cc23)cc1 CHEMBL1917444 IC50 282.0 nM
Cc1c(CC(=O)O)nn(Cc2ccc(Br)cc2F)c(=O)c1C CHEMBL68586 IC50 290.0 nM
CCOC(=O)C1=C(O)C(=O)N(C2c3ccccc3-c3ccccc32)C1 CHEMBL7224 IC50 300.0 nM
O=C(O)Cc1nn(Cc2nc3c(ccc4ccccc43)s2)c(=O)c2ccc(Cl)cc12 CHEMBL279275 IC50 300.0 nM
O=C(/C=C/c1ccc(O)c(O)c1)O[C@@H]1C[C@](O)(C(=O)O)C[C@@H](O)[C@H]1O CHEMBL284616 IC50 300.0 nM
CN1C(=O)Nc2ccccc2[C@@]12NC(=O)NC2=O CHEMBL293869 IC50 310.0 nM
CCOC(=O)C1=C(O)C(=O)N(Cc2ccc(Cl)cc2)C1 CHEMBL7183 IC50 310.0 nM
COc1c(-c2c(C)cc3c(C(C)C)c(O)c(O)c(C=O)c3c2OC)c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c12 CHEMBL114289 Ki 310.0 nM
CC1=N/C(=C\c2ccc(OCC(=O)O)cc2)C(=O)N1CC(=O)O CHEMBL3979826 IC50 310.0 nM
O=C(NCCCCc1ccc(O)cc1)c1cc2ccc(O)cc2oc1=O CHEMBL4071420 IC50 314.0 nM
Cc1ccc2nc(Cn3nc(CC(=O)O)c4ccccc4c3=O)sc2c1F CHEMBL20365 IC50 320.0 nM
Cc1ccc2nc(Cn3nc(CC(=O)O)c4ccccc4c3=O)sc2c1 CHEMBL418008 IC50 320.0 nM
O=C(/C=C/c1ccc(O)cc1)c1ccc(O)cc1O CHEMBL129795 IC50 320.0 nM
O=C(O)Cn1c2c(c3cc(Br)ccc31)CCN(Cc1ccccc1)C2=S CHEMBL1946965 IC50 320.0 nM
O=C(NCCCc1cc(F)cc(F)c1)c1cc2ccc(O)cc2oc1=O CHEMBL4068704 IC50 320.0 nM
COc1cc(/C=C2\SC(=O)N(CC(=O)O)C2=O)ccc1OCc1ccccc1 CHEMBL4455326 IC50 323.0 nM
O=C(O)Cc1ccc2c(c1)OCc1ccccc1C2=O CHEMBL312109 IC50 330.0 nM
O=C(O)CN1C(=O)/C(=C/c2ccc(OCCCCc3ccccc3)cc2)SC1=S CHEMBL5410568 IC50 330.0 nM
O=C(O)Cc1ccc(=O)n(Cc2nc3cc(C(F)(F)F)ccc3s2)n1 CHEMBL69183 IC50 340.0 nM
O=C(NCCCc1cccc(F)c1)c1cc2ccc(O)cc2oc1=O CHEMBL4060049 IC50 340.0 nM
O=C(O)Cc1nn(Cc2nc3c(ccc4ccccc43)s2)c(=O)c2ccc(Cl)cc12 CHEMBL2079662 IC50 350.0 nM
O=S(=O)(c1ccc(Br)cc1)c1ccc(O)nn1 CHEMBL413566 IC50 350.0 nM
O=C(O)Cn1c2c(c3cc(Cl)ccc31)CCN(Cc1ccccc1)C2=S CHEMBL1944853 IC50 350.0 nM
Cc1ccc(F)c(N(C)S(=O)(=O)C[N+](=O)[O-])c1 CHEMBL5290848 IC50 350.0 nM
COc1ccc2c(c1)NC(=O)N(C)C21NC(=O)NC1=O CHEMBL293475 IC50 360.0 nM
CC(C)(C)[C@@H]1C[C@@](O)(CC(=O)O)c2cc(F)ccc2O1 CHEMBL304798 IC50 360.0 nM
O=S(=O)(c1ccc(C(F)(F)F)cc1)c1ccc(O)nn1 CHEMBL372861 IC50 360.0 nM
O=S(=O)(c1ccc2ccccc2c1)c1ccc(O)nn1 CHEMBL369911 IC50 360.0 nM
CC1=N/C(=C\c2ccc(O)cc2)C(=O)N1CC(=O)O CHEMBL3922733 IC50 360.0 nM
O=C(O)CN1C(=O)S/C(=C\c2ccc(OCCc3ccccc3)cc2)C1=O CHEMBL4483615 IC50 364.0 nM
O=C(CN1C(=O)NC2(C1=O)c1ccccc1-c1ccccc12)Nc1ccc(Cl)cc1Cl CHEMBL4458804 IC50 370.0 nM
CC1=C(CC(=O)O)c2cc(F)ccc2/C1=C\c1ccc([S+](C)[O-])cc1 CHEMBL15770 IC50 374.0 nM
CC(C)S(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL18865 IC50 380.0 nM
CCOC(=O)C1=C(O)C(=O)N(Cc2cccs2)C1 CHEMBL6944 IC50 380.0 nM
O=S(=O)(c1ccc(Cl)cc1)c1ccc(O)nn1 CHEMBL425745 IC50 380.0 nM
CC(C)CN1C(=O)N(C)C2(NC(=O)NC2=O)c2ccccc21 CHEMBL66192 IC50 390.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(Cl)c(F)cc2O1 CHEMBL307121 IC50 390.0 nM
O=S(=O)(c1ccc(O)nn1)c1cccc(F)c1F CHEMBL198004 IC50 390.0 nM
O=C(c1ccccc1)c1ccn(-c2cc(F)c(O)c(F)c2)c1 CHEMBL1673027 IC50 390.0 nM
COc1ccc(CCCNC(=O)c2cc3ccc(O)cc3oc2=O)cc1 CHEMBL4084456 IC50 390.0 nM
Cc1cccc2c1C1(NC(=O)NC1=O)N(C)C(=O)N2 CHEMBL63812 IC50 400.0 nM
CN(C)S(=O)(=O)c1ccc2oc3ccc(C(=O)O)cc3c(=O)c2c1 CHEMBL282245 Ki 400.0 nM
CC1(C)C[C@@](O)(CC(=O)O)c2cc([N+](=O)[O-])ccc2O1 CHEMBL67264 IC50 400.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(Cl)c3ccccc3c2O1 CHEMBL421111 IC50 400.0 nM
O=C(COc1cc(O)c2c(=O)cc(-c3ccccc3)oc2c1)OCc1ccc(OCc2c(-c3ccccc3)no[n+]2[O-])cc1 CHEMBL1668046 IC50 400.0 nM
O=C(/C=C/c1ccc(O)c(O)c1)OCc1ccccc1 CHEMBL133714 IC50 400.0 nM
CCOC(=O)C1=C(O)C(=O)N(Cc2ccc(OC)cc2)C1 CHEMBL414208 IC50 410.0 nM
Cc1ccc2c(c1)c(S(=O)(=O)c1ccc(Cl)cc1)c(C)n2CC(=O)O CHEMBL1917446 IC50 411.0 nM
O=C(O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c2cc3ccccc3cc12 CHEMBL67922 IC50 420.0 nM
O=C(O)Cc1nn(Cc2cc3cccnc3s2)c(=O)c2ccccc12 CHEMBL143872 IC50 420.0 nM
O=C(O)Cc1nn(Cc2nc3cc(Cl)c(Cl)cc3s2)c(=O)c2ccccc12 CHEMBL20925 IC50 420.0 nM
Cc1cccc2c(CC(=O)O)nn(Cc3nc4ccccc4s3)c(=O)c12 CHEMBL19838 IC50 420.0 nM
O=S(=O)(Cc1ccccc1F)c1ccc(O)nn1 CHEMBL199069 IC50 422.0 nM
CN1C(=O)Nc2cc(N3CCOCC3)c([N+](=O)[O-])cc2C12NC(=O)NC2=O CHEMBL61955 IC50 430.0 nM
O=C(O)Cc1nn(CC(=O)Nc2ccccc2Cl)c(=O)c2ccccc12 CHEMBL357074 IC50 430.0 nM
O=C(O)Cc1nn(CC(=O)Nc2ccc(Cl)cc2)c(=O)c2ccccc12 CHEMBL342524 IC50 440.0 nM
CCOC(=O)C1=C(O)C(=O)N(Cc2ccccn2)C1 CHEMBL6828 IC50 440.0 nM
O=S(=O)(c1ccc(O)nn1)c1nc2ccccc2s1 CHEMBL73330 IC50 450.0 nM
O=S(=O)(c1ccc(O)nn1)c1cc2cccc(Cl)c2[nH]1 CHEMBL197678 IC50 450.0 nM
O=C(O)Cc1nn(Cc2csc(-c3ccccc3F)n2)c(=O)c2ccccc12 CHEMBL143387 IC50 460.0 nM
O=C(O)Cc1nn(CCc2nc3cc(C(F)(F)F)ccc3s2)c(=O)c2ccccc12 CHEMBL21101 IC50 460.0 nM
O=C1NC(=O)C(c2cc(Cl)ccc2[S+]([O-])Cc2ccc(Cl)cc2)N1 CHEMBL19781 IC50 470.0 nM
CN1C(=O)Nc2ccc([N+](=O)[O-])c(Cl)c2C12NC(=O)NC2=O CHEMBL63527 IC50 470.0 nM
O=C(O)Cc1nn(Cc2noc(-c3ccccc3C(F)(F)F)n2)c(=O)c2ccccc12 CHEMBL2111987 IC50 470.0 nM
COc1ccccc1-c1noc(Cn2nc(CC(=O)O)c3ccccc3c2=O)n1 CHEMBL356545 IC50 470.0 nM
O=C1NC(=O)C2(CCCCC2)N1S(=O)(=O)c1ccc(Cl)s1 CHEMBL5276874 IC50 470.0 nM
O=S(=O)(c1ccc(F)cc1)c1ccc(O)nn1 CHEMBL425922 IC50 474.0 nM
CN1C(=O)Nc2cc([N+](=O)[O-])ccc2C12NC(=O)NC2=O CHEMBL65316 IC50 480.0 nM
COc1cccc(/C=C2\SC(=O)N(CC(=O)O)C2=O)c1 CHEMBL1645383 IC50 480.0 nM
C[C@@H]1C[C@]2(NC(=O)NC2=O)c2cc(Br)cnc2O1 CHEMBL54342 IC50 500.0 nM
CCOC(=O)C1=C(O)C(=O)N(Cc2ccc(Br)cc2)C1 CHEMBL7603 IC50 500.0 nM
Cc1cc2c(C(C)C)c(O)c(O)c(C=O)c2c(O)c1-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O CHEMBL51483 Ki 500.0 nM
O=S(=O)(Cc1ccccc1C(F)(F)F)c1ccc(O)nn1 CHEMBL197544 IC50 500.0 nM
O=C(O)Cc1nn(Cc2nc3c(ccc4ccccc43)s2)c(=O)c2ccccc12 CHEMBL20756 IC50 510.0 nM
COc1ccc(/C=C2\N=C(C)N(CC(=O)O)C2=O)cc1 CHEMBL3936476 IC50 510.0 nM
C/C(=N\NC(=S)Nc1cccc(Br)c1)c1ccc2c(c1)NC(=O)CO2 CHEMBL4779373 IC50 520.0 nM
O=C(O)Cc1nn(Cc2nc3ccc(Br)cc3o2)c(=O)c2ccccc12 CHEMBL143903 IC50 540.0 nM
O=S(=O)(c1ccc(O)nn1)c1ccccc1F CHEMBL198119 IC50 540.0 nM
CC1=N/C(=C\c2cccc3ccccc23)C(=O)N1CC(=O)O CHEMBL3926455 IC50 540.0 nM
O=C(O)COc1cc(Cl)ccc1C(=O)NCc1ccc(Br)cc1 CHEMBL4128992 IC50 550.0 nM
O=C(O)Cn1cc(Cc2nc3cc(F)c(F)cc3s2)c2ccccc21 CHEMBL191951 IC50 560.0 nM
O=C(/C=C/c1ccc(O)cc1)c1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O[C@@H]2OC[C@](O)(CO)[C@H]2O)cc1O CHEMBL1940910 IC50 560.0 nM
CC(C)c1ccc(S(=O)(=O)N2C(=O)NC(=O)C23CCCc2ccccc23)cc1 CHEMBL4451105 IC50 560.0 nM
CC(C)[C@@H]1C[C@@](O)(CC(=O)O)c2cc(F)ccc2O1 CHEMBL68091 IC50 570.0 nM
NC(=O)[C@H]1C[C@]2(NC(=O)NC2=O)c2cc(F)ccc2O1 CHEMBL84060 IC50 570.0 nM
O=C(/C=C/c1ccc(O)c(O)c1)OCCc1ccccc1 CHEMBL319244 IC50 570.0 nM
CS(=O)(=O)c1c(C2NC(=O)NC2=O)cc(Cl)cc1C(F)(F)F CHEMBL440790 IC50 580.0 nM
CCCNS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL429059 IC50 580.0 nM
CC1=N/C(=C\c2ccccc2)C(=O)N1CC(=O)O CHEMBL3917477 IC50 580.0 nM
O=S(=O)(c1ccc(O)nn1)c1cc2ccccc2[nH]1 CHEMBL72278 IC50 590.0 nM
O=S(=O)(c1ccccc1)c1ccc(O)nn1 CHEMBL74814 IC50 600.0 nM
O=C(O)C[C@]1(O)CCOc2ccc(F)cc21 CHEMBL68635 IC50 600.0 nM
O=S(=O)(Cc1ccccc1)c1ccc(O)nn1 CHEMBL199028 IC50 600.0 nM
O=c1cc(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL151 IC50 600.0 nM
CS(=O)(=O)c1c(Cl)cc(Cl)cc1C1NC(=O)NC1=O CHEMBL277427 IC50 610.0 nM
CS(=O)(=O)c1ccc(F)cc1C1NC(=O)NC1=O CHEMBL19885 IC50 610.0 nM
CSc1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL278584 IC50 620.0 nM
O=C(O)Cc1nn(Cc2nc3cc(Cl)cc(C(F)(F)F)c3s2)c(=O)c2ccccc12 CHEMBL278583 IC50 620.0 nM
CC[C@@H]1C[C@@](O)(CC(=O)O)c2cc(F)ccc2O1 CHEMBL306591 IC50 620.0 nM
O=C(O)Cc1nn(Cc2nc(-c3ccc(F)cc3F)no2)c(=O)c2ccccc12 CHEMBL356286 IC50 630.0 nM
CC(=O)c1ccc(S(=O)(=O)N2C(=O)NC(=O)C23CCCc2ccccc23)cc1 CHEMBL4539238 IC50 640.0 nM
O=S(=O)(c1ccc(O)nn1)c1cc2ccc(Cl)cc2[nH]1 CHEMBL372815 IC50 645.0 nM
CC(=O)c1ccc2c(c1)[C@](O)(CC(=O)O)C[C@@H](C)O2 CHEMBL69646 IC50 650.0 nM
CC1=N/C(=C\c2ccc(F)cc2)C(=O)N1CC(=O)O CHEMBL3908530 IC50 650.0 nM
COc1ccc(C2CC3(CN(CC(=O)O)C(=O)O3)c3cc(Br)ccc3O2)cc1 CHEMBL5289568 IC50 650.0 nM
O=C(O)Cc1nn(Cc2ncc(-c3ccccc3)o2)c(=O)c2ccccc12 CHEMBL140042 IC50 660.0 nM
COc1cc(C(F)(F)F)c2sc(Cn3nc(CC(=O)O)c4ccccc4c3=O)nc2c1 CHEMBL431108 IC50 660.0 nM
O=C(O)Cn1cc(Cc2nc3ccc(Cl)cc3s2)c2ccccc21 CHEMBL192213 IC50 660.0 nM
O=S(=O)(Cc1ccc(Br)cc1F)c1ccc(O)nn1 CHEMBL197628 IC50 667.0 nM
O=C(O)Cc1nn(Cc2cc(-c3ccccc3)ns2)c(=O)c2ccccc12 CHEMBL357435 IC50 670.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c2ccccc12 CHEMBL70247 IC50 680.0 nM
O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2cc(Br)ccc12 CHEMBL279666 IC50 690.0 nM
O=C(O)Cn1cc(Cc2nc3c(F)cc(F)cc3s2)c2ccccc21 CHEMBL192534 IC50 690.0 nM
CCCCNS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O CHEMBL19064 IC50 700.0 nM
COc1cc(OC)c2sc(Cn3nc(CC(=O)O)c4ccccc4c3=O)nc2c1 CHEMBL19162 IC50 700.0 nM
O=C(O)Cc1ccc2c(c1)SCc1ccccc1C2=O CHEMBL75245 IC50 700.0 nM
CC(=O)Nc1cccc2c1c(S(=O)(=O)c1ccc(Cl)cc1)c(C)n2CC(=O)O CHEMBL1917449 IC50 708.0 nM
O=C(O)Cc1nn(Cc2snc3ccccc23)c(=O)c2ccccc12 CHEMBL143569 IC50 720.0 nM
O=C(/C=C/c1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1)c1ccc(O)cc1O CHEMBL599763 IC50 720.0 nM
O=C(CN1C(=O)NC2(CCCCC2)C1=O)Nc1ccc(Br)cc1 CHEMBL4442588 IC50 720.0 nM
O=C(/C=C/c1cc(O)c(O)cc1[N+](=O)[O-])O[C@H](Cc1cc(O)c(O)cc1[N+](=O)[O-])C(=O)O CHEMBL261703 IC50 741.0 nM
O=C(COc1cc(O)c2c(=O)cc(-c3ccccc3)oc2c1)OCc1c(-c2ccccc2)no[n+]1[O-] CHEMBL470376 IC50 750.0 nM
O=C(O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c2ncccc12 CHEMBL69371 IC50 760.0 nM
O=C(O)Cc1cc(O)c2c(=O)c3ccccc3ccc2c1 CHEMBL77283 IC50 760.0 nM
CN1C(=O)Nc2ccc(Cl)cc2[C@]12NC(=O)NC2=O CHEMBL65701 IC50 770.0 nM
O=C1Cc2ccc3c(c2O1)CCc1ccccc1C3=O CHEMBL311679 IC50 770.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2ccc(Cl)c(Cl)c2O1 CHEMBL65967 IC50 780.0 nM
CC(=O)Nc1cccc2c1c(Sc1ccc(Cl)cc1)c(C)n2CC(=O)O CHEMBL1914489 IC50 794.0 nM
CN1C(=O)N(C)C2(NC(=O)NC2=O)c2ccccc21 CHEMBL66636 IC50 800.0 nM
Cc1ccc2c(c1)C1(NC(=O)NC1=O)N(C)C(=O)N2 CHEMBL291842 IC50 800.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(Cl)ccc2O1 CHEMBL69708 IC50 820.0 nM
O=C(O)Cc1ccc2c(c1)CCc1ccc(O)cc1C2=O CHEMBL538917 IC50 830.0 nM
CCOC(=O)C1=C(O)C(=O)N([C@H](C)c2ccccc2)C1 CHEMBL269089 IC50 840.0 nM
CN1C(=O)Nc2cccc(Cl)c2C12NC(=O)NC2=O CHEMBL63866 IC50 860.0 nM
O=C(O)Cc1nn(Cc2cc3ccccc3[nH]2)c(=O)c2ccccc12 CHEMBL342786 IC50 870.0 nM
O=S(=O)(c1ccc(O)nn1)c1ccc(F)cc1F CHEMBL363415 IC50 870.0 nM
C[C@H]1C[C@]2(NC(=O)NC2=O)c2cc(Cl)cnc2O1 CHEMBL294612 IC50 890.0 nM
CC(=O)Oc1cc(OCC(=O)OCc2c(-c3ccccc3)no[n+]2[O-])cc2oc(-c3ccccc3)cc(=O)c12 CHEMBL1668048 IC50 900.0 nM
O=C1NC(=O)C2(N1)c1ccccc1-c1ccc(C3CC3)cc12 CHEMBL5483061 IC50 903.0 nM
C[C@H]1Oc2ccc(F)cc2[C@](O)(CC(=O)O)[C@H]1C CHEMBL69586 IC50 910.0 nM
O=C(CN1C(=O)NC2(C1=O)c1ccccc1-c1ccccc12)Nc1ccc(Br)cc1 CHEMBL4554231 IC50 930.0 nM
O=C(CN1C(=O)S/C(=C\c2ccc(O)cc2)C1=O)Nc1ccccc1O CHEMBL5429519 IC50 950.0 nM
CCC[C@@H]1C[C@@](O)(CC(=O)O)c2cc(F)ccc2O1 CHEMBL71562 IC50 970.0 nM
CCN1C(=O)Nc2ccccc2C12NC(=O)NC2=O CHEMBL63389 IC50 1000.0 nM
O=C(O)Cc1nn(Cc2cc3cc(Br)ccc3s2)c(=O)c2ccccc12 CHEMBL422824 IC50 1000.0 nM
O=C(O)Cc1nn(Cc2nc3ccc(O)cc3s2)c(=O)c2ccccc12 CHEMBL278832 IC50 1000.0 nM
O=C(O)Cc1ccc2c(=O)c3ccccc3ccc2c1 CHEMBL77601 IC50 1000.0 nM
C[C@@H]1C[C@@](O)(CC(=O)O)c2cc(Cl)cc(Cl)c2O1 CHEMBL303952 IC50 1000.0 nM
O=C(O)Cn1cc(Cc2nc3ccc(F)cc3s2)c2ccccc21 CHEMBL193570 IC50 1000.0 nM
Cc1c(Sc2ccc(Cl)cc2)c2c(NS(C)(=O)=O)cccc2n1CC(=O)O CHEMBL1917433 IC50 1000.0 nM