CCc1c(CCC(=O)O)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12 CHEMBL2323508 IC50 0.09 nM
COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(CCl)cc1 CHEMBL2323472 IC50 0.12 nM
COc1ccc2c(c1)c(C)c(CCC(=O)O)n2C(=O)c1ccc(Cl)cc1 CHEMBL2323507 IC50 0.13 nM
COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(C)cc1 CHEMBL179587 IC50 0.16 nM
COc1ccc2c(c1)c1c(n2C(=O)c2ccc(Cl)cc2)CCC(C(=O)O)C1 CHEMBL2323522 IC50 0.16 nM
COc1ccc2c(c1)c(CC(=O)NS(=O)(=O)C(F)(F)F)cn2C(=O)c1ccc(Cl)cc1 CHEMBL2323490 IC50 0.21 nM
COc1ccc2c(c1)c(CCC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL178687 IC50 0.22 nM
COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(C(F)(F)F)cc1 CHEMBL2323474 IC50 0.27 nM
Cc1ccc2[nH]c(C(=O)N3CCC(CC(C)(C)O)CC3)cc2c1 CHEMBL2413849 IC50 0.34 nM
COc1ccc2c(c1)c(C)c(CCC(=O)NS(C)(=O)=O)n2C(=O)c1ccc(Cl)cc1 CHEMBL2323511 IC50 0.34 nM
Cc1cc(C2=CC[C@H]3[C@@H]4CCc5cc(C(=O)N(C)CCC(=O)O)ccc5[C@H]4CC[C@]23C)cnn1 CHEMBL4110932 IC50 0.5 nM
COc1ccc2c(c1)c(CC(=O)NS(=O)(=O)C(F)(F)F)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL2323481 IC50 0.74 nM
C[C@H](CC(=O)O)NC(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cncc(F)c3)=CC[C@@H]12 CHEMBL4113242 IC50 0.8 nM
COc1ccc2c(c1)c(CC(=O)O)cn2C(=O)c1ccc(Cl)cc1 CHEMBL503179 IC50 0.96 nM
C[C@@H](CC(=O)O)NC(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cncc(F)c3)=CC[C@@H]12 CHEMBL3914633 IC50 1.2 nM
CN(CCC(=O)O)C(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cncc(F)c3)=CC[C@@H]12 CHEMBL4108488 IC50 1.3 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)NCC5(C(=O)O)CCOCC5)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1 CHEMBL4110197 IC50 1.4 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)N[C@@H]5CCC[C@@H]5C(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1 CHEMBL4114888 IC50 1.8 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)N5CCC[C@H]5C(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1 CHEMBL4110193 IC50 1.9 nM
CC(C)(O)CC1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 CHEMBL2413850 IC50 2.1 nM
CN(CCC(=O)O)C(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cccnc3)=CC[C@@H]12 CHEMBL4106472 IC50 2.5 nM
CCC(C(=O)O)c1ccc(-c2ccc(C)c(F)c2)c(C(F)(F)F)c1 CHEMBL5421222 IC50 2.85 nM
CC1(C)CC[C@@]2(CC[C@H]3[C@@H]4CCc5ccccc5[C@H]4CC[C@@]32C)OC1=O CHEMBL477677 IC50 2.9 nM
O=C(N1CCOCC1)N1CCN(c2ccc(Cl)cc2Cl)CC1 CHEMBL3103330 IC50 3.0 nM
Cc1noc(C)c1COc1ccccc1C(=O)Nc1ccccc1Cl CHEMBL5441020 IC50 3.04 nM
CC1(C)CC[C@@]2(CC[C@H]3[C@@H]4CCc5cc(C(N)=O)ccc5[C@H]4CC[C@@]32C)OC1=O CHEMBL521703 IC50 3.2 nM
CC(C)(CNC(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cncc(F)c3)=CC[C@@H]12)C(=O)O CHEMBL4109884 IC50 3.6 nM
CCC(C(C)=O)c1ccc(-c2cc(Cl)cc(Cl)c2)c(C(F)(F)F)c1 CHEMBL5412756 IC50 3.78 nM
O=C(O)C1(c2ccc(-c3cc(Cl)cc(Cl)c3)c(F)c2)CC1 CHEMBL5438441 IC50 3.78 nM
CN(CCC(=O)O)C(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cncc(C(F)(F)F)c3)=CC[C@@H]12 CHEMBL4112723 IC50 4.2 nM
COc1cncc(C2=CC[C@H]3[C@@H]4CCc5cc(C(=O)N(C)CCC(=O)O)ccc5[C@H]4CC[C@]23C)c1 CHEMBL4109088 IC50 4.4 nM
O=C(c1cc2ccccc2[nH]1)N1CCC(CCO)CC1 CHEMBL2413860 IC50 4.5 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)NCC(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1 CHEMBL4111690 IC50 4.9 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)N5CCC[C@@H]5C(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1 CHEMBL4107895 IC50 5.3 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3cc(Br)ccc3C2)c1 CHEMBL2172122 pIC50 6.026 nM
CC1CC[C@@]2(CC[C@H]3[C@@H]4CCc5ccccc5[C@H]4CC[C@@]32C)OC1=O CHEMBL514854 IC50 6.1 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)NCCCC(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1 CHEMBL4111336 IC50 6.8 nM
CC1(C)CC[C@@]2(CCC3C4CCc5cc(C(N)=O)ccc5C4CC[C@]32C)OC1=O CHEMBL4106762 Ki 6.9 nM
COc1cncc(C2=CC[C@H]3[C@@H]4CCc5cc(C(=O)NCCC(=O)O)ccc5[C@H]4CC[C@]23C)c1 CHEMBL4109717 IC50 6.9 nM
COc1cncc(C2=CC[C@H]3[C@@H]4CCc5cc(C(=O)NCCCC(=O)O)ccc5[C@H]4CC[C@]23C)c1 CHEMBL4114361 IC50 7.3 nM
Cc1c(Cl)cccc1Nc1ccccc1C(=O)O CHEMBL121626 Ki 8.0 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)NCCC(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1 CHEMBL4112035 IC50 8.3 nM
CC(C)(NC(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cncc(F)c3)=CC[C@@H]12)C(=O)O CHEMBL4107023 IC50 8.5 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)NCCC(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(C(F)(F)F)c1 CHEMBL4113533 IC50 8.5 nM
CC1Cc2ccccc2CN1S(=O)(=O)c1cccc(C(=O)O)c1 CHEMBL2172110 pIC50 8.511 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3cc(Cl)ccc3C2)c1 CHEMBL2172121 IC50 8.7 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3c(cccc3[N+](=O)[O-])C2)c1 CHEMBL2172112 IC50 8.9 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)NCC5(C(=O)O)CCCC5)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1 CHEMBL4113686 IC50 8.9 nM
COc1ccccc1NC(=O)c1ccccc1OCc1c(C)noc1C CHEMBL5393759 IC50 8.92 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)NCC5(C(=O)O)CC5)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1 CHEMBL4106813 IC50 9.2 nM
COCCOc1cc2c(cc1OC(N)=O)[C@H]1CC[C@@]3(C)[C@@H](CC[C@@]34CCC(C)(C)C(=O)O4)[C@@H]1CC2 CHEMBL490978 IC50 9.5 nM
O=S(=O)(c1cccc(-c2nn[nH]n2)c1)N1CCc2ccccc2C1 CHEMBL2172067 IC50 9.5 nM
COc1cncc(C2=CC[C@H]3[C@@H]4CCc5cc(C(=O)NCC(C)(C)C(=O)O)ccc5[C@H]4CC[C@]23C)c1 CHEMBL4106458 IC50 9.8 nM
C[C@]12CC[C@@H]3c4ccccc4CC[C@H]3[C@@H]1CC[C@@]21CCCC(=O)O1 CHEMBL514995 IC50 10.0 nM
O=C(N1CCOCC1)N1CCN(c2ccc(I)cc2)CC1 CHEMBL3103349 IC50 10.0 nM
COc1ccc2[nH]c(C(=O)N3CCC(CC(C)(C)O)CC3)cc2c1 CHEMBL4513510 IC50 10.0 nM
O=C(O)C1(c2ccc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)c(F)c2)CC1 CHEMBL5398653 IC50 10.66 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3c(Cl)cccc3C2)c1 CHEMBL2172113 pIC50 10.96 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3c(Br)cccc3C2)c1 CHEMBL2172114 pIC50 10.96 nM
CC1CCCCN1S(=O)(=O)c1ccc(N2CCCC2=O)cc1 CHEMBL2333520 IC50 11.0 nM
CN(CCC(=O)O)C(=O)c1ccc2c(c1)CC[C@H]1[C@@H]3[C@@H](O)C=C(c4cncc(F)c4)[C@@]3(C)CC[C@H]21 CHEMBL4111431 IC50 11.0 nM
COc1ccc(OCc2c(C)noc2C)c(C(=O)Nc2ccccc2)c1 CHEMBL5434454 IC50 11.54 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3ccc(Br)cc3C2)c1 CHEMBL2172087 IC50 12.0 nM
CC(O)CC1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 CHEMBL2413851 IC50 12.0 nM
O=C(N1CCOCC1)N1CCN(c2ccc(Br)cc2)CC1 CHEMBL3103348 IC50 12.0 nM
O=C(O)c1cccc(S(=O)(=O)C2CCc3ccccc3C2)c1 CHEMBL3935879 pIC50 12.88 nM
Cc1ccc2c(c1)CN(S(=O)(=O)c1cccc(C(=O)O)c1)CC2 CHEMBL2172220 pIC50 12.88 nM
COCCOc1cc2c(cc1C#N)[C@H]1CC[C@@]3(C)[C@@H](CC[C@@]34CCC(C)(C)C(=O)O4)[C@@H]1CC2 CHEMBL490979 IC50 13.0 nM
CNC(=O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL2172072 IC50 13.0 nM
O=C(c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1)N1CCOCC1 CHEMBL2172069 IC50 13.0 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL1566492 IC50 13.0 nM
CC(=O)CC1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 CHEMBL2413852 IC50 13.0 nM
O=C(N1CCOCC1)N1CCN(c2ccc(Cl)cc2CO)CC1 CHEMBL3103332 IC50 13.0 nM
Cc1cc(Cl)ccc1N1CCN(C(=O)N2CCOCC2)CC1 CHEMBL3103331 IC50 13.0 nM
Cc1cc(C(C)C(=O)O)ccc1-c1ccc(F)c(F)c1 CHEMBL5439018 IC50 13.3 nM
COc1cc(C(C)C(=O)O)ccc1-c1cc(C(F)(F)F)cc(C(F)(F)F)c1 CHEMBL5409615 IC50 13.49 nM
CN(C)C(=O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL2172073 IC50 14.0 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3ccc(I)cc3C2)c1 CHEMBL2172088 IC50 14.0 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3c(I)cccc3C2)c1 CHEMBL2172115 IC50 14.0 nM
Cc1ccc(-c2ccc(C3(C(=O)O)CC3)cc2F)cc1F CHEMBL5422070 IC50 14.27 nM
CC1CCCN(S(=O)(=O)c2ccc(N3CCCC3=O)cc2)C1 CHEMBL2333523 IC50 15.0 nM
CC(C(=O)O)c1ccc(-c2ccc([N+](=O)[O-])cc2)c(C(F)(F)F)c1 CHEMBL5413682 IC50 15.26 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3c(O)cccc3C2)c1 CHEMBL2172116 pIC50 15.85 nM
COc1cccc2c1CCN(S(=O)(=O)c1cccc(C(=O)O)c1)C2 CHEMBL2172117 pIC50 15.85 nM
COc1cccc(NC(=O)c2ccccc2OCc2c(C)noc2C)c1 CHEMBL1475833 IC50 15.97 nM
CC1CC[C@@]2(CC[C@H]3[C@@H]4CCc5cc(O)ccc5[C@H]4CC[C@@]32C)OC1=O CHEMBL478490 IC50 16.0 nM
C[C@]12C[C@H](F)[C@@H]3c4ccc(C(=O)NCCCC(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1 CHEMBL3931031 IC50 16.8 nM
Cc1ccc2c(c1)CCN(S(=O)(=O)c1cccc(C(=O)O)c1)C2 CHEMBL2172118 pIC50 16.98 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3ccc([N+](=O)[O-])cc3C2)c1 CHEMBL2172084 pIC50 16.98 nM
CCC(C(=O)O)c1ccc(-c2cc(OC)cc(OC)c2)c(C(F)(F)F)c1 CHEMBL5436517 IC50 17.32 nM
Cc1noc(C)c1COc1ccccc1C(=O)Nc1cccc(Cl)c1 CHEMBL5407958 IC50 17.4 nM
CN(CCC(=O)O)C(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cncnc3)=CC[C@@H]12 CHEMBL4114196 IC50 17.8 nM
O=C(N1CCOCC1)N1CCN(c2ccc(Cl)cc2)CC1 CHEMBL3103347 IC50 18.0 nM
CC1CC(=O)O[C@]2(CC[C@H]3[C@@H]4CCc5cc(O)ccc5[C@H]4CC[C@@]32C)C1 CHEMBL478491 IC50 19.0 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3cccc(Cl)c3C2)c1 CHEMBL2172091 IC50 19.0 nM
C[C@@H]1CCCCN1S(=O)(=O)c1ccc(N2CCCC2=O)cc1 CHEMBL2333522 IC50 19.0 nM
CCC(C(=O)O)c1ccc(-c2cccc([N+](=O)[O-])c2)c(C(F)(F)F)c1 CHEMBL5437831 IC50 19.72 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3ccc(Cl)cc3C2)c1 CHEMBL2172086 pIC50 19.95 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@]21CCCC(=O)O1 CHEMBL515655 IC50 20.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2ccccc2)c(OCc2cccc(O)c2)c1 CHEMBL3337721 IC50 20.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1ccccc1C(F)(F)F CHEMBL4640154 IC50 20.0 nM
CC(C(=O)O)c1ccc(-c2cccc(C(F)(F)F)c2)c(F)c1 CHEMBL5427233 IC50 20.0 nM
CC(C(=O)O)c1ccc(-c2ccc(C=O)cc2)c(C(F)(F)F)c1 CHEMBL5406588 IC50 20.0 nM
CC(C(=O)O)c1ccc(-c2ccc(Cl)c(Cl)c2)c(C(F)(F)F)c1 CHEMBL5419326 IC50 20.0 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3ccc(F)cc3C2)c1 CHEMBL2172085 pIC50 20.89 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)N5CCC(C(=O)O)CC5)cc4CC[C@H]3[C@@H]1CC=C2c1cncc(F)c1 CHEMBL4109713 IC50 21.0 nM
CCc1ccccc1NC(=O)c1cc2cccc(O)c2oc1=N CHEMBL4642187 IC50 21.0 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3cc([N+](=O)[O-])ccc3C2)c1 CHEMBL2172119 pIC50 21.88 nM
C[C@H]1CCC[C@H](C)N1S(=O)(=O)c1ccc(N2CCCC2=O)cc1 CHEMBL2333525 IC50 22.0 nM
O=C(N1CCOCC1)N1CCN(c2ccc(C(F)(F)F)cc2)CC1 CHEMBL3103346 IC50 22.0 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)NCCCC(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncnc1 CHEMBL4110314 IC50 23.5 nM
Cc1ccc(C(=O)NCc2ccccc2)c(OCc2c(C)noc2C)c1 CHEMBL5430200 IC50 23.68 nM
COc1ccc(NC(=O)c2ccccc2OCc2c(C)noc2C)cc1 CHEMBL5427510 IC50 23.87 nM
O=C1CCCN1c1ccc(S(=O)(=O)N2CCc3ccccc3C2)cc1 CHEMBL2172076 IC50 24.0 nM
CC1c2ccccc2CCN1S(=O)(=O)c1cccc(C(=O)O)c1 CHEMBL2172109 IC50 24.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1ccc(C(F)(F)F)cc1 CHEMBL4642852 IC50 24.0 nM
CN(CCC(=O)O)C(=O)c1ccc2c(c1)CC[C@H]1[C@@H]3[C@H](O)C=C(c4cncc(F)c4)[C@@]3(C)CC[C@H]21 CHEMBL4113965 IC50 24.2 nM
COc1ccc(OCc2c(C)noc2C)c(C(=O)Nc2ccccc2OC)c1 CHEMBL5395625 IC50 24.38 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3sccc3C2)c1 CHEMBL2172224 IC50 25.0 nM
O=C(O)c1cccc(S(=O)(=O)C2CCc3sccc3C2)c1 CHEMBL3944826 IC50 25.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1ccc(F)cc1 CHEMBL4644092 IC50 25.0 nM
Cc1noc(C)c1COc1ccccc1C(=O)Nc1ccccc1 CHEMBL5408898 IC50 26.11 nM
Cc1noc(C)c1COc1ccccc1C(=O)Nc1ccc(Cl)cc1 CHEMBL5414860 IC50 26.44 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3cc(O)ccc3C2)c1 CHEMBL2172124 pIC50 26.92 nM
Cc1ccc(NC(=O)c2cc3cccc(O)c3oc2=N)cc1 CHEMBL4648793 IC50 27.0 nM
CC1(C)CC[C@@]2(CC[C@H]3[C@@H]4CCc5cc(O)ccc5[C@H]4CC[C@@]32C)OC1=O CHEMBL515032 IC50 28.0 nM
N#Cc1ccc2c(c1)CCN(S(=O)(=O)c1cccc(C(=O)O)c1)C2 CHEMBL2172120 pIC50 28.84 nM
COc1ccc2c(c1)CN(S(=O)(=O)c1cccc(C(=O)O)c1)CC2 CHEMBL2172090 pIC50 28.84 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1cccc(F)c1 CHEMBL4634960 IC50 29.0 nM
C[C@]12CC[C@@H]3c4ccc(C(=O)NCCC(=O)O)cc4CC[C@H]3[C@@H]1CC=C2c1cncnc1 CHEMBL4110768 IC50 29.7 nM
COc1ccc(Nc2ccccc2C(=O)O)c([N+](=O)[O-])c1 CHEMBL2043307 IC50 30.0 nM
O=C(O)c1cccc(Nc2ccc([N+](=O)[O-])cc2)c1 CHEMBL1682200 IC50 30.0 nM
O=C(O)c1cccc(Nc2ccc(C(F)(F)F)cc2[N+](=O)[O-])c1 CHEMBL2041555 IC50 30.0 nM
O=C(O)c1ccccc1Nc1cc(C(F)(F)F)ccc1[N+](=O)[O-] CHEMBL3899044 IC50 30.0 nM
CC(C)c1ccccc1NC(=O)c1cc2cccc(O)c2oc1=N CHEMBL4641899 IC50 30.0 nM
CC(=O)c1cccc(-c2ccc(C(C)C(=O)O)cc2C(F)(F)F)c1 CHEMBL5393766 IC50 30.0 nM
CCC(C(=O)O)c1ccc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(F)c1 CHEMBL5395406 IC50 30.0 nM
O=C(N1CCOCC1)N1CCN(c2ccc(Br)cn2)CC1 CHEMBL3103334 IC50 31.0 nM
CC[C@@H](C(=O)O)c1ccc2cc(OC)ccc2c1 CHEMBL4435662 Ki 31.0 nM
O=C(O)[C@@H]1CCCN(S(=O)(=O)c2ccc3ccccc3c2)C1 CHEMBL2172078 pIC50 31.62 nM
COCCC1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 CHEMBL2413853 IC50 33.0 nM
N#Cc1ccc2c(c1)CN(S(=O)(=O)c1cccc(C(=O)O)c1)CC2 CHEMBL2172089 pIC50 33.88 nM
CCc1cccc(NC(=O)c2cc3cccc(O)c3oc2=N)c1 CHEMBL4646593 IC50 34.0 nM
O=C(NCCc1ccncc1)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL2172075 IC50 35.0 nM
O=C(O)c1cccc(Nc2ccc(S(F)(F)(F)(F)F)cc2)c1 CHEMBL3623737 IC50 35.0 nM
Oc1ccc2c(O)ncc(-c3cc(F)c(F)c(F)c3)c2c1 CHEMBL4439327 IC50 35.0 nM
O=C(O)c1ccccc1Nc1ccc(S(F)(F)(F)(F)F)cc1 CHEMBL3623738 IC50 36.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1ccccc1 CHEMBL4639909 IC50 36.0 nM
COc1ccc(C(=O)Nc2ccccc2)c(OCc2c(C)noc2C)c1 CHEMBL5422118 IC50 36.88 nM
Cc1ccc2[nH]c(C(=O)N3CCC(CCO)CC3)cc2c1 CHEMBL2413863 IC50 37.0 nM
COc1ccc(OCc2c(C)noc2C)c(C(=O)NCc2ccccc2)c1 CHEMBL5423738 IC50 37.66 nM
COc1ccc2c(c1)CCN(S(=O)(=O)c1cccc(C(=O)O)c1)C2 CHEMBL2172125 IC50 38.0 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3cc(I)ccc3C2)c1 CHEMBL2172123 pIC50 38.9 nM
O=C(O)c1ccccc1Nc1cccc([N+](=O)[O-])c1 CHEMBL2043300 IC50 40.0 nM
CC(C)(C)c1ccc(Nc2ccccc2C(=O)O)cc1 CHEMBL2043305 IC50 40.0 nM
CC(=O)c1ccc(Nc2cccc(C(=O)O)c2)c(C(=O)O)c1 CHEMBL2041554 IC50 40.0 nM
COc1ccc(Nc2cccc(C(=O)O)c2)c([N+](=O)[O-])c1 CHEMBL2041556 IC50 40.0 nM
O=C(O)c1cccc(Nc2ccc([N+](=O)[O-])cc2OC(F)(F)F)c1 CHEMBL2041557 IC50 40.0 nM
CC(=O)c1ccc(C(=O)O)c(Nc2ccccc2C(=O)O)c1 CHEMBL3973623 IC50 40.0 nM
COc1ccc([N+](=O)[O-])c(Nc2ccccc2C(=O)O)c1 CHEMBL3945188 IC50 40.0 nM
CC(C(=O)O)c1ccc(-c2ccc(C(F)(F)F)cc2)c(F)c1 CHEMBL193971 IC50 40.0 nM
CCC(C(=O)O)c1ccc(-c2cccc(C(N)=O)c2)c(C(F)(F)F)c1 CHEMBL5436664 IC50 40.0 nM
CCC(C(=O)O)c1ccc(-c2ccc3cc(OC)ccc3c2)c(C(F)(F)F)c1 CHEMBL5405863 IC50 40.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccccc3)c2)cc1 CHEMBL5411357 IC50 40.0 nM
C#Cc1ccc2c(c1)CN(S(=O)(=O)c1cccc(C(=O)O)c1)CC2 CHEMBL2172221 pIC50 41.69 nM
O=C(O)c1cncc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL2172093 pIC50 41.69 nM
CN1CC(c2ccc(S(=O)(=O)N3CCc4ccccc4C3)cc2)CC1=O CHEMBL3953458 pIC50 41.69 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@]21CCCCC(=O)O1 CHEMBL478280 IC50 42.0 nM
CCc1ccc(NC(=O)c2cc3cccc(O)c3oc2=N)cc1 CHEMBL4641012 IC50 45.0 nM
CC(C)(CNC(=O)c1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)C(c3cncnc3)=CC[C@@H]12)C(=O)O CHEMBL4114865 IC50 45.5 nM
CC(C)=CCc1cc(/C=C/C(=O)O)ccc1OC(=O)CCc1ccccc1 CHEMBL511708 Ki 46.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1cccc(Cl)c1 CHEMBL4639417 IC50 46.0 nM
O=C(O)c1cccc(S(=O)(=O)N2Cc3ccccc3C2)c1 CHEMBL1443272 pIC50 46.77 nM
CC(C)c1cccc(NC(=O)c2cc3cccc(O)c3oc2=N)c1 CHEMBL4637597 IC50 47.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1cc(F)c(F)c(F)c1 CHEMBL4634140 IC50 47.0 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@]21CC=CC(=O)O1 CHEMBL477676 IC50 49.0 nM
O=C(O)c1ccccc1Nc1cccc(C(F)(F)F)c1 CHEMBL23588 IC50 50.0 nM
CC(=O)c1ccc(Nc2cccc(C(=O)O)c2)cc1 CHEMBL1682201 IC50 50.0 nM
COc1ccc2cc([C@@H](C)C(=O)O)ccc2c1 CHEMBL1618254 IC50 50.0 nM
CSc1ccc2cc([C@@H](C)C(=O)O)ccc2c1 CHEMBL4437291 IC50 50.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1cccc(C(F)(F)F)c1 CHEMBL4633866 IC50 50.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3cccc(F)c3)c2)cc1 CHEMBL5417484 IC50 50.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(-c4ccccc4)cc3)c2)cc1 CHEMBL5432550 IC50 50.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc4ncnn4c3)c2)cc1 CHEMBL5436074 IC50 51.0 nM
Cc1ccccc1NC(=O)c1cc2cccc(O)c2oc1=N CHEMBL4636345 IC50 52.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1ccc(Cl)cc1 CHEMBL4641799 IC50 52.0 nM
Nc1cccc2c1CCN(S(=O)(=O)c1cccc(C(=O)O)c1)C2 CHEMBL2172111 pIC50 52.48 nM
O=C(O)c1cccc(Nc2ccc([N+](=O)[O-])c3c([N+](=O)[O-])cccc23)c1 CHEMBL4758386 IC50 53.0 nM
Cc1cccc(NC(=O)c2cc3cccc(O)c3oc2=N)c1 CHEMBL4649502 IC50 55.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1ccccc1Cl CHEMBL4640248 IC50 56.0 nM
O=C(O)c1ccccc1Nc1cccc(S(F)(F)(F)(F)F)c1 CHEMBL3623735 IC50 57.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1ccc(C(F)(F)F)cc1C(F)(F)F CHEMBL4640782 IC50 58.0 nM
O=C(CO)N1CCN(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)CC1 CHEMBL3103323 IC50 59.0 nM
COc1ccc(C(=O)O)c(Nc2cccc(C(F)(F)F)c2)c1 CHEMBL2043310 IC50 60.0 nM
O=C(O)c1cccc(Nc2ccc(C(F)(F)F)cc2)c1 CHEMBL1682202 IC50 60.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)cc(C(=O)NCc2ccc(N(C)C)cc2)c1 CHEMBL4467043 IC50 60.0 nM
CSc1ccc2cc(C(C)C(=O)O)ccc2c1 CHEMBL4551048 IC50 60.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1cccc(O)c1 CHEMBL82085 IC50 60.0 nM
COc1ccccc1-c1ccc(C(C)C(=O)O)cc1C(F)(F)F CHEMBL5430302 IC50 60.0 nM
COc1cccc(-c2ccc(C(C)C(=O)O)cc2C(F)(F)F)c1 CHEMBL5398973 IC50 60.0 nM
COc1cc(C(C)C(=O)O)ccc1-c1ccc(Cl)c(Cl)c1 CHEMBL5426142 IC50 60.0 nM
CCC(C(=O)O)c1ccc(-c2cccc([N+](=O)[O-])c2)c(F)c1 CHEMBL5401215 IC50 60.0 nM
CCC(C(=O)O)c1ccc(-c2ccc(Cl)c(Cl)c2)c(C(F)(F)F)c1 CHEMBL5422601 IC50 60.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(Cl)cc3)c2)cc1 CHEMBL5412889 IC50 60.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(F)cc3)c2)cc1 CHEMBL5437220 IC50 60.0 nM
O=C(O)C(=O)Nc1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL2172065 pIC50 61.66 nM
CC(C)=CCc1ccc(/C=C/C(=O)O)cc1NC(=O)CCc1ccccc1 CHEMBL4470997 pIC50 63.1 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1ccccc1F CHEMBL4642678 IC50 64.0 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1C[C@@H]1CCCC(=O)O[C@@H]12 CHEMBL477880 IC50 66.0 nM
O=C(O)c1cn(S(=O)(=O)c2ccc(Br)cc2)c2ccccc12 CHEMBL2172108 pIC50 67.61 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3ccc(-c4nn[nH]n4)cc3C2)c1 CHEMBL2172083 IC50 68.0 nM
COc1ccc(Cn2nnc(O)c2C(=O)Nc2cccc(-c3ccccc3)c2)cc1 CHEMBL5194388 IC50 69.0 nM
O=C(O)c1ccccc1Nc1ccc(Cl)cc1 CHEMBL2043303 IC50 70.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)cc(C(=O)NCCc2ccccc2)c1 CHEMBL4473138 IC50 70.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)cc(C(=O)NCc2ccc(C)cc2)c1 CHEMBL4467986 IC50 70.0 nM
COc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(CC=C(C)C)c2)cc1 CHEMBL4592947 IC50 70.0 nM
CSc1ccc2cc([C@H](C)C(=O)O)ccc2c1 CHEMBL1236131 IC50 70.0 nM
CCc1cnn2c(NCc3ccc[n+]([O-])c3)cc(N3CCCC[C@H]3CCO)nc12 CHEMBL2103840 Ki(app) 70.0 nM
CC(C)(C(=O)O)c1ccc(-c2cc(Cl)cc(Cl)c2)c(F)c1 CHEMBL5413689 IC50 70.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccccc3F)c2)cc1 CHEMBL5405662 IC50 70.0 nM
Cc1noc(C)c1COc1ccc(Cl)cc1C(=O)Nc1ccccc1 CHEMBL5396688 IC50 71.7 nM
COC(=O)C1CC[C@@]2(CC[C@H]3[C@@H]4CCc5cc(O)ccc5[C@H]4CC[C@@]32C)OC1=O CHEMBL478282 IC50 72.0 nM
COc1ccc(C(=O)NCc2ccccc2)c(OCc2c(C)noc2C)c1 CHEMBL5407337 IC50 75.47 nM
CC(C)=CCc1ccc(/C=C/C(=O)O)cc1NC(=O)CCc1cccc(F)c1 CHEMBL4459691 IC50 76.0 nM
Cc1noc(C)c1COc1ccc([N+](=O)[O-])cc1C(=O)NCc1ccccc1 CHEMBL5408394 IC50 76.22 nM
O=C(NN1CCOCC1)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL3923444 pIC50 77.62 nM
CC(C)=CCc1ccc(/C=C/C(=O)O)cc1OC(=O)CCc1ccccc1 CHEMBL4457540 pIC50 79.43 nM
O=C(O)c1cccc(Nc2ccc([N+](=O)[O-])c3ccccc23)c1 CHEMBL2023820 IC50 80.0 nM
COc1ccc(C(=O)O)c(Nc2cccc([N+](=O)[O-])c2)c1 CHEMBL2043313 IC50 80.0 nM
COc1ccc(C(=O)O)c(Nc2ccc(C(C)(C)C)cc2)c1 CHEMBL2040884 IC50 80.0 nM
COC(=O)c1cccc(Nc2ccc([N+](=O)[O-])c3ccccc23)c1 CHEMBL3950016 IC50 80.0 nM
CC(C(=O)O)c1ccc(-c2cccc(C(=O)O)c2)c(C(F)(F)F)c1 CHEMBL5403794 IC50 80.0 nM
CCC(C(=O)O)c1ccc(-c2ccc3c(c2)OCO3)c(C(F)(F)F)c1 CHEMBL5396002 IC50 80.0 nM
C/C=C\Cc1cc(/C=C/C(=O)O)cc(C(=O)NCc2ccc(C)cc2)c1 CHEMBL5409789 IC50 80.0 nM
CC(C)=CCOc1cc(/C=C/C(=O)O)cc(C(=O)NCc2ccc(C)cc2)c1 CHEMBL5409918 IC50 80.0 nM
Cc1noc(C)c1COc1cc(Cl)ccc1C(=O)NCc1ccccc1 CHEMBL5439765 IC50 80.34 nM
COc1ccccc1CCC(=O)Nc1cc(/C=C/C(=O)O)ccc1CC=C(C)C CHEMBL4457830 IC50 81.0 nM
CC(=O)c1ccc(Nc2cccc(C(=O)O)c2)c2ccccc12 CHEMBL4795494 IC50 82.0 nM
O=C(O)c1cccc(Nc2cccc(S(F)(F)(F)(F)F)c2)c1 CHEMBL3623736 IC50 86.0 nM
COc1cccc(CCC(=O)Nc2cc(/C=C/C(=O)O)ccc2CC=C(C)C)c1 CHEMBL4561928 IC50 89.0 nM
COc1ccc(Nc2ccccc2C(=O)O)cc1 CHEMBL1596993 IC50 90.0 nM
CC(C(=O)O)c1ccc(-c2cccc([N+](=O)[O-])c2)c(F)c1 CHEMBL5410510 IC50 90.0 nM
Cc1cc(C(C)C(=O)O)ccc1-c1ccc(Cl)c(Cl)c1 CHEMBL5401700 IC50 90.0 nM
CCC(C(=O)O)c1ccc(-c2ccc([N+](=O)[O-])cc2)c(C(F)(F)F)c1 CHEMBL5439918 IC50 90.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(Br)cc3)c2)cc1 CHEMBL5402185 IC50 90.0 nM
CC(C)=CCc1ccc(/C=C/C(=O)O)cc1NC(=O)CCc1ccc(F)cc1 CHEMBL4581405 IC50 91.0 nM
COc1ccc(CCC(=O)Nc2cc(/C=C/C(=O)O)ccc2CC=C(C)C)cc1 CHEMBL4543354 IC50 94.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(Oc4ccccc4)cc3)c2)cc1 CHEMBL5427873 IC50 94.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc4nccnc4c3)c2)cc1 CHEMBL5401206 IC50 94.0 nM
Cc1noc(C)c1COc1ccccc1C(=O)NCc1ccccc1 CHEMBL5404386 IC50 95.88 nM
Cc1noc(C)c1COc1ccc(Cl)cc1C(=O)NCc1ccccc1 CHEMBL5437111 IC50 96.47 nM
CC(C)=CCc1ccc(/C=C/C(=O)O)cc1NC(=O)/C=C/c1ccccc1 CHEMBL4453512 IC50 98.0 nM
CC(C)=CCc1ccc(/C=C/C(=O)O)cc1NC(=O)CCc1ccccc1F CHEMBL4442981 IC50 98.0 nM
O=C1CC(c2ccccc2O)Oc2ccccc21 CHEMBL75897 IC50 100.0 nM
COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL6 IC50 100.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)cc(C(=O)NCCc2ccc(F)cc2)c1 CHEMBL4538670 IC50 100.0 nM
CCOc1ccc2cc(C(C)C(=O)O)ccc2c1 CHEMBL4457933 IC50 100.0 nM
CC(C(=O)O)c1ccc(-c2ccc3ccccc3c2)c(C(F)(F)F)c1 CHEMBL5404373 IC50 100.0 nM
CCC(C(=O)O)c1ccc(-c2ccc(Cl)nc2)c(C(F)(F)F)c1 CHEMBL5428274 IC50 100.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(C)cc3)c2)cc1 CHEMBL5407493 IC50 100.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc4ccccc4c3)c2)cc1 CHEMBL5440460 IC50 100.0 nM
Cc1noc(C)c1COc1ccccc1C(=O)NCCc1ccccc1 CHEMBL1720677 IC50 103.5 nM
C=CCC1CC[C@@]2(CC[C@H]3[C@@H]4CCc5cc(O)ccc5[C@H]4CC[C@@]32C)OC1=O CHEMBL478492 IC50 107.0 nM
O=C(CC1SC(=O)NC1=O)Nc1ccccc1O CHEMBL2172258 Ki 107.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2ccccc2)c(OCc2cccc(F)c2)c1 CHEMBL3337707 IC50 110.0 nM
Cc1ccc(COc2cc(/C=C/C(=O)O)ccc2OC(=O)CCc2ccccc2)cc1 CHEMBL3337705 IC50 110.0 nM
CC(C)=CCc1ccc(/C=C/C(=O)O)cc1NC(=O)CCc1ccc(O)cc1 CHEMBL4441187 IC50 110.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)cc(C(=O)NCc2ccc(OC(F)(F)F)cc2)c1 CHEMBL4532211 IC50 110.0 nM
COc1ccc(CCNC(=O)c2cc(/C=C/C(=O)O)cc(CC=C(C)C)c2)cc1 CHEMBL4547181 IC50 110.0 nM
COc1ccc(Cn2nnc(O)c2C(=O)Nc2cccc(Oc3ccccc3)c2)cc1 CHEMBL5172658 IC50 110.0 nM
Cc1ccc(-c2ccc(C(C)C(=O)O)cc2F)cc1F CHEMBL5437603 IC50 110.0 nM
COc1cc(C(C)C(=O)O)ccc1-c1ccc(C(F)(F)F)cc1 CHEMBL5434084 IC50 110.0 nM
CCC(C(=O)O)c1ccc(-c2cc(C)cc(C)c2)c(C(F)(F)F)c1 CHEMBL5419024 IC50 110.0 nM
CCC(C(=O)O)c1ccc(-c2cncnc2)c(F)c1 CHEMBL5405175 IC50 110.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc4cccnc4c3)c2)cc1 CHEMBL5408308 IC50 110.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc4c(c3)OCCO4)c2)cc1 CHEMBL5411768 IC50 110.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc4c(c3)OCO4)c2)cc1 CHEMBL5408158 IC50 110.0 nM
C/C=C/Cc1cc(/C=C/C(=O)O)cc(C(=O)NCc2ccc(C)cc2)c1 CHEMBL5403375 IC50 110.0 nM
O=C(O)c1cccc(Nc2ccc(Br)cc2)c1 CHEMBL1682204 IC50 120.0 nM
COc1ccc2c(c1)c(C)c(CC(C)(C)C(=O)O)n2C(=O)c1ccc(Cl)cc1 CHEMBL2323509 IC50 120.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)cc(C(=O)OCCc2ccccc2)c1 CHEMBL4545749 IC50 120.0 nM
CCc1ccc2cc(C(C)C(=O)O)ccc2c1 CHEMBL4446810 IC50 120.0 nM
CCC(C(=O)O)c1ccc2cc(OC)ccc2c1 CHEMBL4437071 IC50 120.0 nM
CC[C@H](C(=O)O)c1ccc2cc(OC)ccc2c1 CHEMBL4466610 IC50 120.0 nM
CC(C(=O)O)c1ccc(-c2ccccc2C(F)(F)F)c(F)c1 CHEMBL194686 IC50 120.0 nM
CCC(C(=O)O)c1ccc(-c2cccc(OC)c2)c(F)c1 CHEMBL5427069 IC50 120.0 nM
CCC(C(=O)O)c1ccc(-c2cc(C)cc(C)c2)c(F)c1 CHEMBL5406928 IC50 120.0 nM
CC(C(=O)O)c1ccc(-c2cnc3ccccc3c2)c(F)c1 CHEMBL5406064 IC50 120.0 nM
CC[C@@H](NC(=O)c1cc(/C=C/C(=O)O)cc(-c2ccc(C(C)C)cc2)c1)c1ccccc1 CHEMBL5401567 IC50 120.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)ccc1OC(=O)CCc1ccccc1F CHEMBL4467992 IC50 125.0 nM
COc1cccc(CCC(=O)Oc2ccc(/C=C/C(=O)O)cc2CC=C(C)C)c1 CHEMBL4543333 IC50 126.0 nM
O=C(O)c1cccc(Nc2ccc(Cl)cc2)c1 CHEMBL1682203 IC50 130.0 nM
CC(=O)c1ccc(Nc2ccccc2C(=O)O)cc1 CHEMBL2043302 IC50 130.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)cc(NC(=O)CCc2ccccc2)c1 CHEMBL4460107 IC50 130.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)cc(C(=O)NCc2cccc(OC(F)(F)F)c2)c1 CHEMBL4587755 IC50 130.0 nM
CCOc1ccc2c(c1)CC(C(=O)N(C)Cc1cc(C(=O)O)c(C)o1)CO2 CHEMBL5179823 IC50 130.0 nM
CCC(C(=O)O)c1ccc(-c2ccnc(Cl)c2)c(C(F)(F)F)c1 CHEMBL5408142 IC50 130.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(F)cc3F)c2)cc1 CHEMBL5397612 IC50 130.0 nM
COc1ccc(CCC(=O)Oc2ccc(/C=C/C(=O)O)cc2CC=C(C)C)cc1 CHEMBL4582279 IC50 132.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)ccc1OC(=O)CCc1ccc(F)cc1 CHEMBL4580471 IC50 135.0 nM
COc1ccccc1CCC(=O)Oc1ccc(/C=C/C(=O)O)cc1CC=C(C)C CHEMBL4574718 IC50 135.0 nM
CC(=O)c1cccc(Nc2ccccc2C(=O)O)c1 CHEMBL2043301 IC50 140.0 nM
CC(=O)c1ccc(Nc2ccc(C(F)(F)F)cc2)c(C(=O)O)c1 CHEMBL2040999 IC50 140.0 nM
O=C(O)c1cccc(S(=O)(=O)NCCc2ccc(Cl)cc2)c1 CHEMBL2172096 IC50 140.0 nM
COc1ccc(C(=O)n2c(C)c(CC(=O)O)c3cc(OC)ccc32)cc1 CHEMBL2323473 IC50 140.0 nM
O=C1CCCN1c1ccc(S(=O)(=O)N2CCCCC2)cc1 CHEMBL1726890 IC50 140.0 nM
O=C(c1cc2ccccc2[nH]1)N1CC(CCO)C1 CHEMBL2413855 IC50 140.0 nM
CC(C)=CCc1ccc(/C=C/C(=O)O)cc1NC(=O)CCc1cccc(O)c1 CHEMBL4526918 IC50 140.0 nM
CCC(C(=O)O)c1ccc(-c2cccc(C(=O)O)c2)c(C(F)(F)F)c1 CHEMBL5427755 IC50 140.0 nM
O=C(O)C1(c2ccc(-c3cccc(C(F)(F)F)c3)c(F)c2)CC1 CHEMBL5420885 IC50 140.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)c2)cc1 CHEMBL5422271 IC50 140.0 nM
O=C(O)c1ccccc1Nc1cccc(Cl)c1 CHEMBL22815 IC50 150.0 nM
COc1ccc(C(=O)O)c(Nc2ccc(Br)cc2)c1 CHEMBL2043321 IC50 150.0 nM
O=C(O)c1cccc(Nc2ccccc2[N+](=O)[O-])c1 CHEMBL2041154 IC50 150.0 nM
COc1cc(C(C)C(=O)O)ccc1-c1cccc(C(F)(F)F)c1 CHEMBL5397312 IC50 150.0 nM
CC(C(=O)O)c1ccc(-c2cccnc2)c(F)c1 CHEMBL5413361 IC50 150.0 nM
CC(C(=O)O)c1ccc(-c2ccc3ccccc3c2)c(F)c1 CHEMBL5440432 IC50 150.0 nM
CCC(C(=O)O)c1ccc(-c2ccc3nc(C)ccc3c2)c(C(F)(F)F)c1 CHEMBL5423363 IC50 150.0 nM
O=C(O)C1(c2ccc(-c3cnc4ccccc4c3)c(F)c2)CC1 CHEMBL5436838 IC50 150.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)ccc1OC(=O)CCc1cccc(F)c1 CHEMBL4590593 IC50 156.0 nM
COc1cc2c(cc1OC)CN(S(=O)(=O)c1cccc(C(=O)O)c1)CC2 CHEMBL2172092 pIC50 158.49 nM
O=C(O)c1ccccc1Nc1ccc([N+](=O)[O-])cc1 CHEMBL1574420 IC50 160.0 nM
COc1ccc(C(=O)O)c(Nc2cccc(Cl)c2)c1 CHEMBL2043314 IC50 160.0 nM
Cc1ccc2[nH]c(C(=O)N3CCC(CCCO)CC3)cc2c1 CHEMBL2413861 IC50 160.0 nM
Cc1ccc(COc2cc(/C=C/C(=O)O)ccc2OC(=O)CCc2cccc(F)c2)cc1 CHEMBL3337711 IC50 160.0 nM
CCCCCc1n[nH]c2c1C(c1cc(OC)c(O)c([N+](=O)[O-])c1)C(C#N)=C(N)O2 CHEMBL4290064 IC50 160.0 nM
O=C(O)/C=C/c1cc(OCc2ccccc2)cc(C(=O)NCCc2ccccc2)c1 CHEMBL4568995 IC50 160.0 nM
Cc1noc(C)c1COc1ccccc1C(=O)NCCc1ccc(S(N)(=O)=O)cc1 CHEMBL1894580 IC50 160.0 nM
Cc1noc(C)c1COc1ccc([N+](=O)[O-])cc1C(=O)Nc1ccccc1 CHEMBL5434555 IC50 160.2 nM
CCCCCCc1n[nH]c2c1C(c1cc(OC)c(O)c([N+](=O)[O-])c1)C(C#N)=C(N)O2 CHEMBL4282842 IC50 168.0 nM
NC(=O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL2172068 pIC50 169.82 nM
COc1ccc(-c2cc(/C=C/C(=O)O)cc(C(=O)NCc3ccc(C)cc3)c2)cc1 CHEMBL5421383 IC50 170.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(C#N)cc3)c2)cc1 CHEMBL5438117 IC50 170.0 nM
Cc1ccc(CNC(=O)c2cc(Br)cc(/C=C/C#N)c2)cc1 CHEMBL5436263 IC50 170.0 nM
CC(C)=CCc1ccc(/C=C/C(=O)O)cc1NC(=O)CCc1cccc(OS(=O)(=O)c2ccc(C)cc2)c1 CHEMBL4452028 IC50 180.0 nM
COc1ccc2cc([C@H](C)C(=O)O)ccc2c1 CHEMBL154 IC50 180.0 nM
Cc1ccc(CNC(=O)c2cc(C#Cc3ccccc3)cc(/C=C/C(=O)O)c2)cc1 CHEMBL5412832 IC50 180.0 nM
Cc1ccc(C(=O)Nc2ccccc2)c(OCc2c(C)noc2C)c1 CHEMBL5399095 IC50 183.9 nM
Cc1noc(C)c1COc1ccc(Cl)cc1C(=O)NCCc1ccccc1 CHEMBL5405458 IC50 185.5 nM
O=C(Nc1cccc(C(F)(F)F)c1)c1c(O)nnn1Cc1ccc(OC(F)(F)F)cc1 CHEMBL4248154 IC50 190.0 nM
CC(C)=CCc1ccc(/C=C/C(=O)O)cc1NC(=O)CCc1ccc(OS(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL4591479 IC50 190.0 nM
COc1ccc(Cc2onc(O)c2C(=O)Nc2cccc(-c3ccccc3)c2)cc1 CHEMBL5174744 IC50 190.0 nM
CCCc1cc(=O)[nH]c(SCC(=O)c2ccc3c(c2)CCCC(=O)N3)n1 CHEMBL5203670 IC50 190.0 nM
Cc1ccc(-c2ccc(C(C)C(=O)O)cc2C(F)(F)F)cc1 CHEMBL5425327 IC50 190.0 nM
CCc1ccc(-c2cc(/C=C/C(=O)O)cc(C(=O)NCc3ccc(C)cc3)c2)cc1 CHEMBL5411601 IC50 190.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(C(C)C)cc3)c2)cc1 CHEMBL5427049 IC50 190.0 nM
Cc1noc(C)c1COc1cc(Cl)ccc1C(=O)Nc1ccccc1 CHEMBL5427074 IC50 194.9 nM
O=C(O)c1cccc(S(=O)(=O)N2CCCc3ccccc32)c1 CHEMBL2172106 pIC50 199.53 nM
CC1CCN(S(=O)(=O)c2ccc(N3CCCC3=O)cc2)CC1 CHEMBL2333524 IC50 200.0 nM
CC(C)=CCc1ccc(NC(=O)CCc2ccccc2)c(/C=C/C(=O)O)c1 CHEMBL4516371 IC50 200.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)ccc1NC(=O)CCc1ccccc1 CHEMBL4441387 IC50 200.0 nM
Cc1oc(CN(C)C(=O)CCc2nc(C3CC3)no2)cc1C(=O)O CHEMBL5180458 IC50 200.0 nM
CSc1cccc(-c2ccc(C(C)C(=O)O)cc2F)c1 CHEMBL5403144 IC50 200.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(C(F)(F)F)cc3)c2)cc1 CHEMBL5403238 IC50 200.0 nM
COC(=O)/C=C/c1cc(Br)cc(C(=O)NCc2ccc(C)cc2)c1 CHEMBL5425839 IC50 200.0 nM
Cc1noc(C)c1COc1cc(Cl)ccc1C(=O)NCCc1ccccc1 CHEMBL5403464 IC50 201.03 nM
O=C(O)c1cccc(S(=O)(=O)N2CCc3ccccc32)c1 CHEMBL2172225 pIC50 208.93 nM
O=C(O)c1cccc(S(=O)(=O)NCCc2cccc(Cl)c2)c1 CHEMBL2172095 pIC50 208.93 nM
COc1ccc(Cn2nnc(O)c2C(=O)Nc2cccc(-c3cccc(O)c3)c2)cc1 CHEMBL5204156 IC50 210.0 nM
Cc1cc(C(C)C(=O)O)ccc1-c1cccc([N+](=O)[O-])c1 CHEMBL5400783 IC50 210.0 nM
CCCCc1n[nH]c2c1C(c1cc(OC)c(O)c([N+](=O)[O-])c1)C(C#N)=C(N)O2 CHEMBL4279383 IC50 213.0 nM
COc1ccc(OCc2c(C)noc2C)c(C(=O)NCCc2ccccc2)c1 CHEMBL5412169 IC50 213.8 nM
O=C(O)c1cccc(S(=O)(=O)NCCc2ccccc2)c1 CHEMBL1871992 pIC50 218.78 nM
Cc1cccc(CCNS(=O)(=O)c2cccc(C(=O)O)c2)c1 CHEMBL2169909 pIC50 218.78 nM
COc1ccc(C(=O)O)c(Nc2ccc(Cl)cc2)c1 CHEMBL2043320 IC50 220.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2ccccc2)c(OCc2ccc(F)cc2)c1 CHEMBL3337458 IC50 220.0 nM
N=c1oc2c(O)cccc2cc1C(=O)Nc1ccc(F)c(F)c1 CHEMBL4648687 IC50 220.0 nM
COc1ccc(Cn2nnc(O)c2C(=O)Nc2cccc(-c3ccc(OC)cc3)c2)cc1 CHEMBL5170149 IC50 220.0 nM
O=C(O)C1(c2ccc(-c3ccc(Cl)c(Cl)c3)c(F)c2)CC1 CHEMBL196945 IC50 220.0 nM
CCCc1n[nH]c2c1C(c1cc(OC)c(O)c([N+](=O)[O-])c1)C(C#N)=C(N)O2 CHEMBL4293881 IC50 227.0 nM
O=C(c1cc2ccccc2[nH]1)N1CCCCC1CCO CHEMBL2413857 IC50 230.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)ccc1OC(=O)CCCc1ccccc1 CHEMBL4587420 IC50 233.0 nM
COc1cc(C2C(C#N)=C(N)Oc3[nH]nc(CCC4CCCC4)c32)cc([N+](=O)[O-])c1O CHEMBL4291554 IC50 237.0 nM
Cc1cccc(Nc2ccccc2C(=O)O)c1 CHEMBL23479 IC50 240.0 nM
COc1ccc(Nc2cc(OC)ccc2C(=O)O)cc1 CHEMBL2043322 IC50 250.0 nM
CC(=O)c1ccc(Nc2ccc(Br)cc2)c(C(=O)O)c1 CHEMBL2041001 IC50 250.0 nM
O=C(O)c1cccc(Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 CHEMBL2041558 IC50 250.0 nM
Cc1c(CC(=O)O)c2cc(F)ccc2n1C(=O)c1ccc(Cl)cc1 CHEMBL2323476 IC50 250.0 nM
CCc1n[nH]c2c1C(c1cc(OC)c(O)c([N+](=O)[O-])c1)C(C#N)=C(N)O2 CHEMBL4286627 IC50 255.0 nM
COc1ccc(Nc2ccc(C(C)=O)cc2C(=O)O)c([N+](=O)[O-])c1 CHEMBL2041006 IC50 260.0 nM
Oc1noc2cccc(Nc3cc(C(F)(F)F)cc(C(F)(F)F)c3)c12 CHEMBL4238437 IC50 260.0 nM
C=CCc1cc(/C=C/C(=O)O)cc(C(=O)NCCc2ccccc2)c1 CHEMBL4577172 IC50 260.0 nM
COc1ccc(Cn2nnc(O)c2C(=O)Nc2cccc(-c3cccc(OC)c3)c2)cc1 CHEMBL5170401 IC50 260.0 nM
CC(C(=O)O)c1ccc(-c2ccc3ncccc3c2)c(F)c1 CHEMBL5398882 IC50 260.0 nM
CCC(C(=O)O)c1ccc(-c2ccc3ccccc3c2)c(F)c1 CHEMBL5437329 IC50 260.0 nM
CC[C@@H](NC(=O)c1cc(/C=C/C(=O)O)cc(-c2ccc(Oc3ccccc3)cc2)c1)c1ccccc1 CHEMBL5435345 IC50 260.0 nM
COc1ccc(Cn2nnc(O)c2C(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 CHEMBL5175151 IC50 270.0 nM
COc1ccccc1-c1ccc(C(C)C(=O)O)cc1C CHEMBL5397522 IC50 270.0 nM
C=CCc1ccc(/C=C/C(=O)O)cc1OC(=O)CCc1ccccc1 CHEMBL4579768 IC50 273.0 nM
CCCc1n[nH]c2c1C(c1ccc(O)c([N+](=O)[O-])c1)C(C#N)=C(N)O2 CHEMBL4287863 IC50 278.0 nM
COc1ccc2c(c1)c1c(n2C(=O)c2cccc(C(F)(F)F)c2)CCC(C(=O)O)C1 CHEMBL2323523 IC50 279.0 nM
CC(C)(C)c1ccc(Nc2cccc(C(=O)O)c2)cc1 CHEMBL1682205 IC50 280.0 nM
CC(=O)c1ccc(Nc2ccc(C(C)(C)C)cc2)c(C(=O)O)c1 CHEMBL2041004 IC50 280.0 nM
CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C CHEMBL717 IC50 280.0 nM
COc1cc(C2C(C#N)=C(N)Oc3[nH]nc(CCC4CCCCC4)c32)cc([N+](=O)[O-])c1O CHEMBL4287291 IC50 287.0 nM
O=C(O)c1cccc(Nc2cccc([N+](=O)[O-])c2)c1 CHEMBL2041158 IC50 290.0 nM
COc1ccc2c(c1)c(C)c(CC(C)C(=O)O)n2C(=O)c1ccc(Cl)cc1 CHEMBL2323510 IC50 290.0 nM
Cc1c(CCC(=O)O)c2cc(F)ccc2n1C(=O)c1ccc(Cl)cc1 CHEMBL2323482 IC50 290.0 nM
COc1cccc(COc2cc(/C=C/C(=O)O)cc(C(=O)NCCc3ccccc3)c2)c1 CHEMBL4442107 IC50 290.0 nM
Cc1cccc(Nc2ccccc2C(=O)O)c1C CHEMBL686 Ki 300.0 nM
O=c1cc(-c2ccccc2O)oc2ccccc12 CHEMBL144278 IC50 300.0 nM
CCCCCC(=O)Oc1ccc(/C=C/C(=O)O)cc1CC=C(C)C CHEMBL4454121 IC50 300.0 nM
COc1ccc2c(c1)c(Cc1nonc1O)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL4434843 IC50 300.0 nM
COc1ccc2c(c1)c(Cc1nonc1O)c(C)n2C(=O)c1ccccc1 CHEMBL5290170 IC50 300.0 nM
Cc1ccc(CNC(=O)c2cc(Br)cc(/C=C/C(=O)O)c2)cc1 CHEMBL5406207 IC50 300.0 nM
O=C(Nc1ccc(Cl)cc1C(=O)O)c1cccc(O)c1 CHEMBL2070002 IC50 310.0 nM
COc1ccc(Cn2nnc(O)c2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 CHEMBL4174786 IC50 310.0 nM
Oc1noc2cccc(Nc3cccc(S(F)(F)(F)(F)F)c3)c12 CHEMBL4249650 IC50 310.0 nM
COc1ccc(Cn2nnc(O)c2C(=O)Nc2cccc(-c3ccc(O)cc3)c2)cc1 CHEMBL5206583 IC50 310.0 nM
O=C(O)c1cccc(Nc2cccc(C(F)(F)F)c2)c1 CHEMBL2041153 IC50 320.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2ccccc2)c(OCc2ccccc2F)c1 CHEMBL3337706 IC50 320.0 nM
Cc1noc(C)c1COc1ccc([N+](=O)[O-])cc1C(=O)NCCc1ccccc1 CHEMBL5415646 IC50 321.9 nM
O=C(O)c1cccc(S(=O)(=O)NCCc2ccccc2F)c1 CHEMBL2172094 IC50 330.0 nM
O=C(O)/C=C/c1cc(C(=O)NCCc2ccccc2)cc(-c2cccc(CO)c2)c1 CHEMBL4547925 IC50 330.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(-c3ccc(CN4CCOCC4)c(F)c3)c2)cc1 CHEMBL5402839 IC50 330.0 nM
COc1ccc2c(c1)c1c(n2C(=O)c2ccc(Cl)cc2)CC(C(=O)O)CC1 CHEMBL2323525 IC50 340.0 nM
CC(C(=O)O)c1ccc(-c2cccc3ccccc23)c(F)c1 CHEMBL5414784 IC50 340.0 nM
O=C(c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1)N1CC2(COC2)C1 CHEMBL2172074 pIC50 346.74 nM
CC(C)=CCc1cc(/C=C/C(=O)O)ccc1OC(=O)c1ccccc1 CHEMBL4472272 IC50 348.0 nM
O=C(Nc1ccc(Br)cc1C(=O)O)c1cccc(O)c1 CHEMBL2070005 IC50 350.0 nM
O=C(N1CCN(c2ccc(Cl)cc2)CC1)N1CCc2ccccc2C1 CHEMBL3103324 IC50 350.0 nM
O=C(N1CCOCC1)N1CCN(Cc2ccc(Cl)cc2)CC1 CHEMBL3103335 IC50 350.0 nM
COc1ccc(N2CCN(C(=O)N3CCOCC3)CC2)cc1 CHEMBL3103363 IC50 350.0 nM
Cc1ccc(Nc2ccccc2C(=O)O)cc1 CHEMBL2043304 IC50 360.0 nM
COc1cc(Nc2cccc(C(=O)O)c2)cc(OC)c1 CHEMBL2041559 IC50 360.0 nM
Cc1ccc(N2CCN(C(=O)N3CCOCC3)CC2)cc1 CHEMBL3103362 IC50 360.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2ccccc2)c(OCc2cc(F)cc(F)c2)c1 CHEMBL3337708 IC50 360.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)ccc1OC(=O)Cc1cccc2ccccc12 CHEMBL4470281 IC50 370.0 nM
N=c1oc2cccc(O)c2cc1C(=O)Nc1ccc(F)cc1 CHEMBL4638008 IC50 370.0 nM
O=C(O)C1CCN(S(=O)(=O)c2ccc3ccccc3c2)C1 CHEMBL2172079 IC50 380.0 nM
O=C(O)c1cccc(Nc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])c1 CHEMBL3962195 Ki 380.0 nM
O=C(O)c1cccc(S(=O)(=O)C2CC=CCC2)c1 CHEMBL3907919 pIC50 389.05 nM
O=C(O)C1CCCN(S(=O)(=O)c2ccc3cc4ccccc4cc3c2)C1 CHEMBL2172063 pIC50 389.05 nM
O=C(O)c1cccc(S(=O)(=O)N2CC=CCC2)c1 CHEMBL2172223 IC50 390.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2ccccc2)c(OCc2ccccc2)c1 CHEMBL3337704 IC50 390.0 nM
O=C(O)[C@H]1CCCN(S(=O)(=O)c2ccc3ccccc3c2)C1 CHEMBL2172077 pIC50 398.11 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2cccc(F)c2)c(OCc2cccc(F)c2)c1 CHEMBL3337716 IC50 400.0 nM
COc1ccc(Cn2nnc(O)c2C(=O)Nc2cccc(C(F)(F)F)c2)cc1OC CHEMBL4238142 IC50 400.0 nM
COc1ccc(Cn2nnc(O)c2C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1 CHEMBL5191752 IC50 400.0 nM
Cc1ccc(CNC(=O)c2cc(Br)cc(/C=C/C(=O)N(C)C)c2)cc1 CHEMBL5397146 IC50 400.0 nM
COc1ccc(C(=O)NCCc2ccccc2)c(OCc2c(C)noc2C)c1 CHEMBL5431806 IC50 413.3 nM
CCCCOc1cc(/C=C/C(=O)O)ccc1OC(=O)CCc1ccccc1 CHEMBL3337700 IC50 420.0 nM
CC(=O)Oc1ccc(/C=C/C(=O)O)cc1CC=C(C)C CHEMBL2269701 IC50 440.0 nM
O=C(NN1CCSCC1)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL3984247 pIC50 446.68 nM
O=C(c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1)N1CCSCC1 CHEMBL2172070 IC50 450.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)ccc1OC(=O)CC1CCCCC1 CHEMBL4537068 IC50 453.0 nM
O=C(O)c1cccc(Nc2cccc(Cl)c2)c1 CHEMBL2041160 IC50 460.0 nM
CC(C(=O)O)c1ccc(-c2ccccc2)c(F)c1 CHEMBL563 IC50 460.0 nM
COc1cc(C2C(C#N)=C(N)Oc3[nH]nc(CCCc4ccccc4)c32)cc([N+](=O)[O-])c1O CHEMBL4295234 IC50 469.0 nM
CC(=O)c1ccc(Nc2ccc(C(C)=O)cc2C(=O)O)cc1 CHEMBL2040998 IC50 470.0 nM
Cc1ccc(COc2cc(/C=C/C(=O)O)ccc2OC(=O)CCc2ccc(F)cc2)cc1 CHEMBL3337712 IC50 470.0 nM
O=C(NCCCc1ccc(F)cc1)c1cc2ccc(O)cc2oc1=O CHEMBL4089817 IC50 470.0 nM
COc1ccc(Cn2nnc(O)c2C(=O)Nc2ccc(-c3ccccc3)cc2)cc1 CHEMBL5187723 IC50 470.0 nM
CCC(C(=O)O)c1ccc(-c2ccc(C(=O)O)cc2)c(C(F)(F)F)c1 CHEMBL5416628 IC50 470.0 nM
O=C(c1ccc(Cl)cc1)N1CCN(C(=O)N2CCOCC2)CC1 CHEMBL3103336 IC50 480.0 nM
O=C(Nc1cccc(C(F)(F)F)c1)c1c(O)nnn1Cc1ccccc1 CHEMBL4166887 IC50 480.0 nM
COc1cc(C2C(C#N)=C(N)Oc3[nH]nc(CC(C)(C)C)c32)cc([N+](=O)[O-])c1O CHEMBL4280914 IC50 480.0 nM
COc1ccc(Nc2cccc(C(=O)O)c2)cc1 CHEMBL1682206 IC50 490.0 nM
COc1ccc(C(=O)O)c(Nc2ccc([N+](=O)[O-])cc2)c1 CHEMBL2043318 IC50 500.0 nM
COc1ccc(C(=O)O)c(Nc2ccc(C(C)=O)cc2)c1 CHEMBL2043319 IC50 500.0 nM
O=C(O)c1ccc(Nc2cccc(C(F)(F)F)c2)cc1 CHEMBL2041562 IC50 500.0 nM
O=C(O)c1ccn(S(=O)(=O)c2ccc3ccccc3c2)n1 CHEMBL2172081 IC50 500.0 nM
O=C(O)Cc1cn(C(=O)c2ccc(Cl)cc2)c2ccc(F)cc12 CHEMBL2323488 IC50 500.0 nM
O=C(N1CCOCC1)N1CCN(c2ccc(F)cc2)CC1 CHEMBL1418164 IC50 500.0 nM
Cc1ccc(CNC(=O)c2cc(C#CC3CC3)cc(/C=C/C(=O)O)c2)cc1 CHEMBL5441078 IC50 500.0 nM
C[C@@H]1C(O)=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3C[C@@H]12 CHEMBL4533498 pIC50 501.19 nM
CCCc1nn(C)c2c1C(c1cc(OC)c(O)c([N+](=O)[O-])c1)C(C#N)=C(N)O2 CHEMBL4294478 IC50 510.0 nM
Cc1ccc(Cl)c(Nc2ccccc2C(=O)O)c1Cl CHEMBL509 IC50 512.0 nM
O=C(O)c1cccc(S(=O)(=O)NCCc2cccc(Oc3ccccc3)c2)c1 CHEMBL2172099 pIC50 524.81 nM
O=C(N1CCOCC1)N1CCN(c2ccc(Cl)nc2)CC1 CHEMBL3103333 IC50 530.0 nM
COc1cc(C2C(C#N)=C(N)Oc3[nH]nc(C)c32)cc([N+](=O)[O-])c1O CHEMBL4294539 IC50 533.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2ccc(F)cc2)c(OCc2cccc(F)c2)c1 CHEMBL3337717 IC50 540.0 nM
Cc1ccc(COc2cc(/C=C/C(=O)O)ccc2OC(=O)CCc2c(F)cc(F)cc2F)cc1 CHEMBL3337713 IC50 540.0 nM
O=C(O)/C=C/c1ccc(-c2cccc(CO)c2)c(NC(=O)CCc2ccccc2)c1 CHEMBL4581432 IC50 540.0 nM
CC(C(=O)O)c1ccc(-c2cccc(C(=O)O)c2)c(F)c1 CHEMBL5418560 IC50 540.0 nM
O=C(O)C1CCCN(S(=O)(=O)c2ccc(-c3ccccc3Cl)cc2)C1 CHEMBL2172060 pIC50 549.54 nM
Oc1noc2cccc(Nc3cccc(C(F)(F)F)c3)c12 CHEMBL4245231 IC50 550.0 nM
O=C(O)c1cccc(Nc2ccccc2C(F)(F)F)c1 CHEMBL2041156 IC50 560.0 nM
CC(=O)c1cccc(Nc2cccc(C(=O)O)c2)c1 CHEMBL2041159 IC50 560.0 nM
CC(C)COc1cc(/C=C/C(=O)O)ccc1OC(=O)CCc1ccccc1 CHEMBL3337701 IC50 560.0 nM
COc1cccc(Nc2ccccc2C(=O)O)c1 CHEMBL1328677 IC50 570.0 nM
COc1cccc(Nc2cc(OC)ccc2C(=O)O)c1 CHEMBL2043315 IC50 570.0 nM
O=C(N1CCOCC1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1 CHEMBL3103356 IC50 570.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2ccccc2)c(OCCc2ccccc2)c1 CHEMBL3337710 IC50 570.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2c(F)cc(F)cc2F)c(OCc2cccc(F)c2)c1 CHEMBL3337718 IC50 580.0 nM
CC(=O)c1ccc(Nc2ccc(Cl)cc2)c(C(=O)O)c1 CHEMBL2041000 IC50 600.0 nM
O=C(O)c1cccc(S(=O)(=O)Nc2ccc3ccccc3c2)c1 CHEMBL2172107 IC50 600.0 nM
COc1ccc(Nc2ccc(C(C)=O)cc2C(=O)O)cc1 CHEMBL2041002 IC50 610.0 nM
CC(=O)c1ccc(Nc2cc(C(=O)O)cc(C(=O)O)c2)c(C(=O)O)c1 CHEMBL2041152 IC50 610.0 nM
Cc1cccc(-c2ccc(C(C)C(=O)O)cc2F)c1 CHEMBL5421708 IC50 630.0 nM
COc1ccc(C(=O)O)c(Nc2cccc(C)c2)c1 CHEMBL2043316 IC50 640.0 nM
Cc1ccc(CCNS(=O)(=O)c2cccc(C(=O)O)c2)cc1 CHEMBL2172100 IC50 640.0 nM
CC(=O)c1cccc(Nc2ccc(C(C)=O)cc2C(=O)O)c1 CHEMBL2040993 IC50 650.0 nM
COc1ccc2cc(CC(=O)O)ccc2c1 CHEMBL1105 IC50 650.0 nM
C#Cc1ccc(N2CCN(C(=O)N3CCOCC3)CC2)cc1 CHEMBL3103345 IC50 660.0 nM
COc1cc(C2C(C#N)=C(N)Oc3[nH]nc(CCC(C)C)c32)cc([N+](=O)[O-])c1O CHEMBL4286233 IC50 676.0 nM
O=C(O)c1cccc(Oc2ccccc2)c1 CHEMBL663 IC50 680.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)cc(CC=C(C)C)c1O CHEMBL456309 Ki 680.0 nM
CCCc1nn(-c2ccccc2F)c2c1C(c1cc(OC)c(O)c([N+](=O)[O-])c1)C(C#N)=C(N)O2 CHEMBL4277845 IC50 683.0 nM
CCCCCCCc1n[nH]c2c1C(c1cc(OC)c(O)c([N+](=O)[O-])c1)C(C#N)=C(N)O2 CHEMBL4293449 IC50 684.0 nM
COc1ccc(C(=O)O)c(Nc2ccc(C(=O)O)cc2)c1 CHEMBL2040851 IC50 690.0 nM
CCCCC/C=C\C/C=C\CCCCCCCC(=O)O CHEMBL267476 IC50 690.0 nM
CCCCC/C=C/C/C=C/C/C=C/C/C=C/CCCC(=O)O CHEMBL267484 IC50 690.0 nM
Cc1ccc(Nc2cccc(C(=O)O)c2)cc1 CHEMBL1682207 IC50 700.0 nM
O=C(N1CCOCC1)N1CCN(c2ccccc2C(F)(F)F)CC1 CHEMBL3103359 IC50 700.0 nM
COc1cc(C(C)C(=O)O)ccc1-c1cccc([N+](=O)[O-])c1 CHEMBL5419770 IC50 700.0 nM
COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(F)cc1 CHEMBL178499 IC50 710.0 nM
CC(=O)c1ccc(Nc2cccc(C(F)(F)F)c2)c(C(=O)O)c1 CHEMBL2040887 IC50 730.0 nM
COc1cc(C2C(C#N)=C(N)Oc3[nH]nc(CCCC(C)C)c32)cc([N+](=O)[O-])c1O CHEMBL4278318 IC50 730.0 nM
CCC(C(=O)O)c1ccc(-c2ccc3cc(OC)ccc3c2)c(F)c1 CHEMBL5431359 IC50 730.0 nM
O=C(O)C1CCCN(S(=O)(=O)c2cccc(-c3ccccc3Cl)c2)C1 CHEMBL2172061 IC50 740.0 nM
COc1cccc(CCNS(=O)(=O)c2cccc(C(=O)O)c2)c1 CHEMBL2172097 IC50 740.0 nM
Cc1ccc2[nH]c(C(=O)N3CCN(CCO)CC3)cc2c1 CHEMBL2413859 IC50 770.0 nM
Cc1ccc(COc2cc(/C=C/C(=O)O)ccc2OC(=O)CCc2ccc(O)cc2)cc1 CHEMBL3337714 IC50 770.0 nM
CCCc1nn(C2CCOC2)c2c1C(c1cc(OC)c(O)c([N+](=O)[O-])c1)C(C#N)=C(N)O2 CHEMBL4279326 IC50 778.0 nM
Cc1ccc2[nH]c(C(=O)N3CCC(CO)CC3)cc2c1 CHEMBL2413864 IC50 790.0 nM
COc1ccc(C(=O)O)c(Nc2ccc(C)cc2)c1 CHEMBL2043323 IC50 800.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2cccc(O)c2)c(OCc2cccc(F)c2)c1 CHEMBL3337719 IC50 800.0 nM
CC(C(=O)O)c1ccc2cc(S(C)(=O)=O)ccc2c1 CHEMBL4459662 IC50 820.0 nM
O=C(Nc1ccc([N+](=O)[O-])cc1C(=O)O)c1cccc(O)c1 CHEMBL2070004 IC50 840.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2ccc(O)cc2)c(OCc2cccc(F)c2)c1 CHEMBL3337720 IC50 840.0 nM
C=C(C)COc1cc(/C=C/C(=O)O)ccc1OC(=O)CCc1ccccc1 CHEMBL3337703 IC50 850.0 nM
CCC1=C(C)CN(C(=O)NCCc2ccc(S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)cc2)C1=O CHEMBL1481 IC50 850.0 nM
CC(C(=O)O)c1ccc(-c2ccc(C(C)(C)C)cc2)c(F)c1 CHEMBL5426283 IC50 850.0 nM
CC(C)=CCc1cc(/C=C/C(=O)O)ccc1NC(=O)CCCc1ccccc1 CHEMBL4468606 IC50 866.0 nM
Cc1cc(C)cc(Nc2ccc(C(=O)O)cc2)c1 CHEMBL2041777 IC50 870.0 nM
Cc1ccc(CNC(=O)c2cc(/C=C/C(=O)O)cc(CC(C)c3ccccc3)c2)cc1 CHEMBL5424035 IC50 880.0 nM
COc1cc(Nc2ccccc2C(=O)O)cc(OC)c1 CHEMBL2043308 IC50 890.0 nM
O=C(O)/C=C/c1ccc(OC(=O)CCc2ccccc2)c(OCc2ccc(Cl)cc2)c1 CHEMBL3337709 IC50 890.0 nM
CN(C)CCNC(=O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 CHEMBL2172071 pIC50 891.25 nM
COc1cc(Nc2ccc(C(C)=O)cc2C(=O)O)cc(OC)c1 CHEMBL2041008 IC50 900.0 nM
Cc1ccc(COc2cc(/C=C/C(=O)O)ccc2OC(=O)CCc2cccc(O)c2)cc1 CHEMBL3337715 IC50 910.0 nM
CC(C)(C)c1ccc(Nc2ccc(C(=O)O)cc2)cc1 CHEMBL2041775 IC50 930.0 nM
O=C(O)c1cccc(Nc2ccccc2)c1 CHEMBL1682198 IC50 940.0 nM
COc1ccc2c(c1)c(Cc1nn(C)nc1O)c(C)n2C(=O)c1ccc(Cl)cc1 CHEMBL4590005 IC50 940.0 nM
Cc1cc(C(C)C(=O)O)ccc1-c1cccc(C(=O)O)c1 CHEMBL5403302 IC50 940.0 nM
CC(=O)c1ccccc1Nc1cccc(C(=O)O)c1 CHEMBL2041155 IC50 960.0 nM
COc1cccc(COc2cc(/C=C/C(=O)O)ccc2OC(=O)CCc2ccccc2)c1 CHEMBL3337722 IC50 960.0 nM
CCOc1cc(/C=C/C(=O)O)ccc1OC(=O)CCc1ccccc1 CHEMBL3337697 IC50 970.0 nM
O=C(O)c1cccc(Nc2ccccc2C(=O)O)c1 CHEMBL348522 IC50 980.0 nM
CC(=O)c1ccc(Nc2cccc([N+](=O)[O-])c2)c(C(=O)O)c1 CHEMBL2040893 IC50 980.0 nM
Cc1ccc(C(=O)NCCc2ccccc2)c(OCc2c(C)noc2C)c1 CHEMBL5427727 IC50 992.6 nM