CC(C)(C)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1 CHEMBL17157 Potency 0.7 nM
CSc1cccc(NC(=S)N(CCCN2CCN(C)CC2)Cc2cccs2)c1 CHEMBL1607827 Potency 3.2 nM
FC(F)(F)c1ccc2c(c1)N1CCCC1CN2 CHEMBL1498452 Potency 3.5 nM
COc1ccc2c(c1)C=C([C@@H]1C[C@H]3CN(c4ccccc4)C(=O)[C@]34CCCN14)CO2 CHEMBL600769 Potency 4.5 nM
CCCNC(=O)NS(=O)(=O)c1cnccc1Sc1ccc(Cl)cc1 CHEMBL1542395 Potency 4.5 nM
CN[C@H](CC(C)C)C(=O)N[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H]2C(=O)N[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)O)c4cc(O)cc(O)c4-c4cc3ccc4O)[C@H](O)c3ccc(c(Cl)c3)Oc3cc2cc(c3O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O[C@H]2C[C@](C)(N)[C@H](O)[C@H](C)O2)Oc2ccc(cc2Cl)[C@H]1O CHEMBL1200628 Potency 4.5 nM
Cc1ccc(Sc2ncccc2C(=O)O)cc1C CHEMBL1576608 Potency 5.0 nM
Cc1[nH]c2ccccc2c1CCN(Cc1cccs1)C(S)=Nc1ccccc1 CHEMBL1441067 Potency 5.0 nM
CCO/C(O)=C(\C(=N)NCCCO)C(=O)c1ccccc1 CHEMBL2369196 Potency 5.0 nM
COc1ccc2c(-c3ccc(C4(C#N)CC4)cc3)c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc2c1 CHEMBL4207222 IC50 5.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(C#N)(c3ccccc3)CC2)CC1 CHEMBL4206892 Ki 5.5 nM
Oc1c2nc3ccc(Br)cc3c-2ncn1CCCn1ccnc1 CHEMBL1300462 Potency 5.6 nM
O=C(Nc1cc(C(F)(F)F)ccc1Cl)C(=O)N1CCCCC1 CHEMBL1328800 Potency 5.6 nM
CCCCC(=O)Nc1ccc(C(=O)Nc2cc(C(F)(F)F)ccc2Cl)cc1 CHEMBL1361393 Potency 5.6 nM
CCOC(=O)c1sc(-c2ccccc2)cc1NC(=O)c1ccc(S(=O)(=O)N(CCOC)CCOC)cc1 CHEMBL1376427 Potency 5.6 nM
C/C(CC(=O)Nc1ccccn1)=N\NC(=O)c1cccc(C)c1 CHEMBL3189457 Potency 6.0 nM
CN(C)S(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2-c2ccc(C3(C#N)CC3)cc2)CC1 CHEMBL4212671 IC50 6.0 nM
CN(C)C(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(C#N)(c3ccccc3)CC2)CC1 CHEMBL4207514 IC50 6.0 nM
N#CC1(c2ccc(-c3c(C(=O)N4CCN(C(=O)C5CC5)CC4)cnc4ccc(F)cc34)cc2)CC1 CHEMBL4211904 IC50 6.0 nM
CC(C)(C#N)c1ccc(-c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccc(F)cc23)cc1 CHEMBL4215704 IC50 6.0 nM
COc1ccc2ncc(C(=O)N3CCN(S(C)(=O)=O)CC3)c(-c3ccc(C4(C#N)CC4)cc3)c2c1 CHEMBL4209722 IC50 7.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(Cl)cc3c2-c2ccc(C3(C#N)CC3)cc2)CC1 CHEMBL4207617 IC50 7.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2-c2ccc(C3(C#N)CCC3)cc2)CC1 CHEMBL4206606 IC50 7.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(C#N)(c3ccccc3F)CC2)CC1 CHEMBL4202680 IC50 7.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2-c2ccc(C3(C#N)CC3)cc2)CC1 CHEMBL4206272 IC50 7.0 nM
CN(C)CCNS(=O)(=O)N(C)C CHEMBL1492006 Potency 7.1 nM
CC(=O)c1ccc(NC(S)=NCCCN2CCOCC2)cc1 CHEMBL1336893 Potency 7.1 nM
CC(C)CCP(=O)(O)c1ccccc1 CHEMBL1327135 Potency 7.5 nM
Nc1ccc(S(=O)(=O)N2CCCCC2c2cccnc2)cc1 CHEMBL1489143 Potency 7.9 nM
Cc1ccc(NC(=O)CCC(=O)OC(C(=O)c2ccc(C)c(C)c2)c2ccccc2)c(C)c1 CHEMBL1507858 Potency 7.9 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3cc(F)c(F)cc3c2-c2ccc(C3(C#N)CC3)cc2)CC1 CHEMBL4212891 IC50 8.0 nM
CN(C)C(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2-c2ccc(C3(C#N)CC3)cc2)CC1 CHEMBL4218688 IC50 8.0 nM
N#CC1(c2ccccc2)CCN(c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4213848 IC50 8.0 nM
CCOc1cc(/C=N/NC(=O)COc2ccc(Cl)cc2)ccc1OS(=O)(=O)c1ccccc1 CHEMBL3189647 Potency 8.9 nM
COc1c2occc2c(OC)c2c(=O)cc(C)oc12 CHEMBL44746 Potency 8.9 nM
CC#CC(C)C(OCOC)C(CC(C)Cc1cc(Br)cc(OCc2ccccc2)c1OC)OC CHEMBL1355293 Potency 8.9 nM
COc1ccc(-c2nnc(SCc3ccccc3)n2N)cc1 CHEMBL1575066 Potency 8.9 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3c(F)cc(F)cc3c2-c2ccc(C3(C#N)CC3)cc2)CC1 CHEMBL4213604 IC50 9.0 nM
CC(C)(C#N)c1ccc(-c2c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc3ccc(F)cc23)c(F)c1 CHEMBL4217115 IC50 9.0 nM
CC(C)(C#N)c1ccc(-c2c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc3ccc(F)cc23)cc1 CHEMBL4214724 IC50 9.0 nM
CCn1cc([C@@H]2C[C@H]3CN(Cc4cccc(Cl)c4)C(=O)[C@]34CCCN24)cn1 CHEMBL1330916 Potency 10.0 nM
OC(COCC1COc2ccccc2O1)CN1CCCCC1 CHEMBL1509142 Potency 10.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccsc3c2N2CCC(C#N)(c3ccccc3)CC2)CC1 CHEMBL4207953 IC50 10.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(C=O)(c3ccccc3)CC2)CC1 CHEMBL4210671 IC50 10.0 nM
O=C1C(=O)N(Cc2ccccc2)c2ccccc21 CHEMBL115581 IC50 10.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3c(F)cc(F)cc3c2N2CCC(C#N)(c3ccccc3)CC2)CC1 CHEMBL4215957 IC50 11.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(C#N)(c3ccc(F)cc3)CC2)CC1 CHEMBL4205368 IC50 11.0 nM
CC(=O)C1(c2ccccc2)CCN(c2c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4205805 IC50 11.0 nM
CCN(Cc1ccncc1)C(=O)C1CCN(S(=O)(=O)c2cccs2)CC1 CHEMBL1569332 Potency 11.2 nM
CSc1nncc(-c2ccc(F)c(F)c2)n1 CHEMBL1415854 Potency 11.2 nM
Cc1ccc(S(=O)(=O)/C=C\C#N)cc1 CHEMBL1562420 Potency 11.2 nM
C=CC(=O)c1ccc2ccccc2c1 CHEMBL154580 Potency 11.2 nM
O=C(CN(c1ccc(F)cc1)S(=O)(=O)c1ccccc1)NCCSC1CCCCC1 CHEMBL1464178 Potency 11.9 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3cc(F)c(F)cc3c2N2CCC(C#N)(c3ccccc3)CC2)CC1 CHEMBL4205051 IC50 12.0 nM
COc1ccc2ncc(C(=O)N3CCN(S(C)(=O)=O)CC3)c(N3CCC(C#N)(c4ccccc4)CC3)c2c1 CHEMBL4213304 IC50 12.0 nM
N#CC1(c2ccccc2)CCN(c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccsc23)CC1 CHEMBL4210811 IC50 12.0 nM
CC(C)(C)c1ccc(-c2c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc3ccc(F)cc23)cc1 CHEMBL4207423 IC50 12.0 nM
CCC1(C#N)CCN(c2c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4216229 IC50 12.0 nM
O=C(CCl)NN=C(c1ccccc1)c1ccccc1 CHEMBL1556750 Potency 12.6 nM
C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12 CHEMBL274826 Potency 12.6 nM
CSc1ccc2c(c1)N(CCC1CCCCN1C)c1ccccc1S2 CHEMBL1200916 Potency 12.6 nM
CSc1ccccc1C(=O)Nc1nccs1 CHEMBL1406724 Potency 12.6 nM
N#CC1(c2ccc(-c3c(C(=O)N4CCN(C(=O)C5CC5)CC4)cnc4ccc(Cl)cc34)cc2)CC1 CHEMBL4204486 IC50 13.0 nM
CC1(C)CC=C(c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4202477 IC50 13.0 nM
N#CC1(CC2CC2)CCN(c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4204489 IC50 13.0 nM
O=C(c1cnc2ccc(Cl)cc2c1N1CCC2(CC1)OCCO2)N1CCN(C(=O)C2CC2)CC1 CHEMBL4214314 IC50 13.0 nM
COc1ccc2c(N3CCC(C#N)(c4ccccc4)CC3)c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc2c1 CHEMBL4216465 IC50 14.0 nM
N#CC1(c2ccccc2)CCN(c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccc(Cl)cc23)CC1 CHEMBL4203073 IC50 14.0 nM
CN(C)S(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(C#N)(c3ccccc3)CC2)CC1 CHEMBL4213024 IC50 14.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2-c2ccc(C3(C#N)CCCC3)cc2)CC1 CHEMBL4208724 IC50 14.0 nM
CC(C)(C)c1ccc(-c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccc(F)cc23)cc1 CHEMBL4214162 IC50 14.0 nM
CCOC(=O)N1CCN(C(=O)c2oc(=O)c3ccccc3c2-c2ccc(C)cc2)CC1 CHEMBL1347603 Potency 14.1 nM
O=C(NC(=S)N1CCCc2ccccc21)c1ccccc1 CHEMBL1392444 Potency 14.1 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(Cl)cc3c2N2CCC(C#N)(c3ccccc3)CC2)CC1 CHEMBL4214533 IC50 15.0 nM
CCC1(C#N)CCN(c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4209360 IC50 15.0 nM
CO[C@@H]1COC(=O)CCC[C@@H](C)[C@H](OC)COC(=O)[C@H](Cc2ccccc2)NC(=O)C/C=C\[C@H]1C CHEMBL1514398 Potency 15.8 nM
Cc1ccccc1OCCNc1ccc(C(F)(F)F)cc1[N+](=O)[O-] CHEMBL1526262 Potency 15.8 nM
CC(C)NC[C@@H](O)COc1cccc2ccccc12 CHEMBL275742 Potency 15.8 nM
CNC(=O)c1ccccc1NC(=O)c1cccc(S(=O)(=O)N2CCCCC2)c1 CHEMBL1539436 Potency 15.8 nM
CN(C)C(=O)CSc1nnc(-c2ccncc2)n1Cc1ccco1 CHEMBL1324679 Potency 15.8 nM
CCOc1ccc(C(=O)CCN2CCCCC2)cc1 CHEMBL1471745 Potency 15.8 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2-c2ccc(C3(C#N)CC3)cc2F)CC1 CHEMBL4209616 IC50 16.0 nM
N#CC1(c2ccc(-c3c(C(=O)N4CCN(C(=O)C5CC5)CC4)cnc4ccsc34)cc2)CC1 CHEMBL4204849 IC50 17.0 nM
CC1(C#N)CCN(c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccsc23)CC1 CHEMBL4214428 IC50 17.0 nM
COc1ccc(S(=O)(=O)c2cnc3ccc(OC)cc3c2N2CCC3(CC2)OCCO3)cc1 CHEMBL1341327 IC50 17.0 nM
Cc1c(C(=O)c2cccc3ccccc23)c2cccc3c2n1[C@H](CN1CCOCC1)CO3 CHEMBL188 Potency 17.8 nM
O=C(CN1CCCC1)Nc1ccccc1C(=O)c1ccccc1 CHEMBL1507462 Potency 17.8 nM
O=C(CCN1CCc2ccccc2C1)c1ccc2c(c1)OCCO2 CHEMBL1429775 Potency 17.8 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC3(CC2)C(=O)Cc2ccccc23)CC1 CHEMBL4209231 IC50 18.0 nM
CC(C)OCCCN=C(S)NNC(=O)c1ccc(Cl)c(Cl)c1 CHEMBL1594492 Potency 18.9 nM
O=C(c1cnc2ccc(F)cc2c1N1CCC2(CCCCC2)CC1)N1CCN(C(=O)C2CC2)CC1 CHEMBL4210851 IC50 19.0 nM
COc1ccc2ncc(C(=O)N3CCN(C(=O)C4CC4)CC3)c(N3CCC4(CC3)OCCO4)c2c1 CHEMBL4216402 IC50 19.0 nM
O=C(c1cnc2ccc(F)cc2c1N1CCC2(CC1)OCCO2)N1CCN(C(=O)C2CC2)CC1 CHEMBL4203770 IC50 19.0 nM
O=C1C=CC(=O)N1c1cccc(-c2ccccc2)c1 CHEMBL567622 Potency 20.0 nM
CCOc1ccccc1NC(=O)Nc1ccc(Cl)cc1 CHEMBL1321591 Potency 20.0 nM
CC1(C)C2CC=C(/C=N/NC(=O)C3CC3)C1C2 CHEMBL3212784 Potency 20.0 nM
Cc1ccc(S(=O)(=O)Nc2cccnc2Oc2ccc(Cl)cc2)cc1 CHEMBL1364014 Potency 20.0 nM
Cc1cccc2c1N(CC(=O)OC(C)C)C(=O)C2=O CHEMBL1480935 Potency 20.0 nM
CCN(CC)C(=O)CN1C(=O)C(=O)c2ccccc21 CHEMBL445719 Potency 20.0 nM
CCOC(=O)CSc1nnc2c(n1)C1(C)CCC2C1(C)C CHEMBL1388301 Potency 20.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccsc3c2-c2ccc(C3(C#N)CC3)cc2)CC1 CHEMBL4210133 IC50 20.0 nM
CCOC(=O)CSc1nc2c(sc3ccccc32)c(=O)n1CCCN1CCCC1 CHEMBL3416562 IC50 20.0 nM
CN(C)C(=S)SSC(=S)N(C)C CHEMBL120563 IC50 20.0 nM
CC1(C)CC=C(c2c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4202537 IC50 21.0 nM
COc1ccc2c(N3CCC4(CC3)OCCO4)c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc2c1 CHEMBL4218208 IC50 21.0 nM
Cc1cc(F)cc2c(N3CCC4(CC3)OCCO4)c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc12 CHEMBL4217482 IC50 22.0 nM
CN1CCN(C(=S)SCC(=O)Nc2nc(-c3ccccc3)c(-c3ccccc3)o2)CC1 CHEMBL1371065 Potency 22.4 nM
Cc1cc(C)n(CCN(C)Cc2nc(Cc3ccccc3F)no2)n1 CHEMBL1572778 Potency 22.4 nM
COc1ccc(-c2nc(-c3ccc4c(c3)OCO4)[nH]c2-c2ccc(OC)cc2)cc1 CHEMBL1582537 Potency 22.4 nM
COc1cc(OC)c(-c2nnc3n(CCc4ccccc4)c(=O)c4ccccc4n23)cc1OC CHEMBL1610058 Potency 22.4 nM
CCOc1ccccc1N1CCN(Cc2cccc(OC)c2OC)CC1 CHEMBL1571798 Potency 22.4 nM
C=CC=O CHEMBL721 Potency 22.4 nM
O=c1c2ccccc2sn1-c1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCCC1 CHEMBL1338317 Potency 22.4 nM
COc1ccc(CN2CCC(CO)(CCOc3ccccc3)CC2)cc1C CHEMBL1505415 Potency 22.4 nM
CC1CCC(=NNC(=O)Cc2ccccc2)CC1 CHEMBL1562053 Potency 22.4 nM
CN(C)CCC(=O)c1ccc2c(c1)OCO2 CHEMBL1408170 Potency 22.4 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(C#N)(c3ccc(Cl)cc3)CC2)CC1 CHEMBL4217083 IC50 23.0 nM
O=C(c1cnc2c(F)cc(F)cc2c1N1CCC2(CC1)OCCO2)N1CCN(C(=O)C2CC2)CC1 CHEMBL4211363 IC50 23.0 nM
O=C(CN(Cc1ccccc1)S(=O)(=O)c1ccccc1)N/N=C/c1ccc([N+](=O)[O-])cc1 CHEMBL3199019 Potency 23.8 nM
OCCNCCCOc1cc(Cl)ccc1Cl CHEMBL1569108 Potency 23.8 nM
CCOCCn1c(CCCO)nc2ccccc21 CHEMBL1586555 Potency 23.8 nM
CC(C)(c1cc(Br)c(O)c(Br)c1)c1cc(Br)c(O)c(Br)c1 CHEMBL184450 Potency 23.8 nM
CN(C)C(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(C)(C#N)CC2)CC1 CHEMBL4217795 IC50 24.0 nM
CN(C)S(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(C)(C#N)CC2)CC1 CHEMBL4213536 IC50 25.0 nM
COC(=O)c1cccnc1 CHEMBL379845 Potency 25.1 nM
COC(=O)N1CCC2(CCCN(Cc3ccccc3)C2)CC1 CHEMBL1553939 Potency 25.1 nM
NC(=O)C1CC(=O)N(c2ccc(OCc3c(Cl)cccc3Cl)cc2)C1 CHEMBL1560311 Potency 25.1 nM
FC(F)(F)c1ccccc1-n1ccnc1 CHEMBL277525 Potency 25.1 nM
O=C(CCC1CCCCC1)Nc1c2c(nn1-c1ccc(F)cc1)C[S+]([O-])C2 CHEMBL1323526 Potency 25.1 nM
COc1ccccc1C(=O)ON=C1c2ccccc2-c2ccccc21 CHEMBL1345723 Potency 25.1 nM
Fc1cccc(Cl)c1/C=N/n1c(S)nnc1-c1cccnc1 CHEMBL3192940 Potency 25.1 nM
Fc1ccc(-c2ccc(Nc3cccc(F)c3)nn2)cc1 CHEMBL1403162 Potency 25.1 nM
O=C(CCN1CCCCC1)c1ccc2c(c1)OCO2 CHEMBL1606959 Potency 25.1 nM
CC(C)NC1(C(N)=O)CCN(Cc2ccccc2)CC1 CHEMBL1325282 Potency 25.1 nM
O=C(CCNc1cccc(F)c1)c1cc2ccccc2o1 CHEMBL1468094 Potency 25.1 nM
CCOC(=O)CN1C(=O)C(=O)c2cccc(C)c21 CHEMBL1387501 Potency 25.1 nM
CN(C)c1ccc(/C=C/C(=O)c2ccccc2)cc1[N+](=O)[O-] CHEMBL1444221 Potency 25.1 nM
COc1cccc(/C=c2/s/c(=C(\C#N)C(=O)N3CCOCC3)n(-c3ccccc3)c2=O)c1 CHEMBL3209557 Potency 25.1 nM
CC(=O)c1ccc(NC2c3ncccc3C(=O)N2Cc2ccc(F)cc2)cc1 CHEMBL1589251 Potency 25.1 nM
CC(C)C(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(C)(C#N)CC2)CC1 CHEMBL4204569 IC50 27.0 nM
O=C(c1cnc2ccc(F)cc2c1N1CCC2(CCCC2)CC1)N1CCN(C(=O)C2CC2)CC1 CHEMBL4215797 IC50 28.0 nM
COc1ccc2ncc(CN3CCN(C(=O)C4CC4)CC3)c(N3CCC4(CC3)OCCO4)c2c1 CHEMBL4213071 IC50 28.0 nM
O/C(=C\c1ccc2ccccc2n1)c1ccc(O)cc1O CHEMBL1497391 Potency 28.2 nM
CC(C)N(C(=O)CN1C(=O)C(=O)c2ccccc21)c1ccccc1 CHEMBL1492228 Potency 28.2 nM
Cc1cc(S(=O)(=O)N2CCC(N3CCCCC3)CC2)ccc1-n1cnnn1 CHEMBL1303550 Potency 28.2 nM
CC(C)N(C(=O)CCl)c1ccccc1 CHEMBL1394829 Potency 28.2 nM
Cc1ccc(NC(=O)c2nn(C34CC5CC(CC(C5)C3)C4)cc2[N+](=O)[O-])cc1 CHEMBL1519076 Potency 28.2 nM
N#CCSc1nc2sc3c(c2c(=O)n1C1CCCCC1)CCCC3 CHEMBL1384601 Potency 28.2 nM
CCN(CC)CCCCCOc1ccccc1OC CHEMBL1546320 Potency 28.2 nM
COc1ccc(NC(=O)Cn2c(=O)n(CC3CCCO3)c(=O)c3ccccc32)c(OC)c1 CHEMBL1307421 Potency 28.2 nM
CC(C)(C)NC(=O)CN(Cc1cccs1)C(=O)CN1C(=O)C(=O)c2ccccc21 CHEMBL1589395 Potency 28.2 nM
COc1ccc(C(=O)CCN(C)C)c2ccccc12 CHEMBL1574278 Potency 28.2 nM
S=C(N/N=C/c1ccc2c(c1)OCO2)NC1CC2CCC1C2 CHEMBL3189493 Potency 28.2 nM
O=S(=O)(c1cc(-c2nc3ccccc3s2)ccc1Cl)N1CCOCC1 CHEMBL1457305 Potency 29.9 nM
CN(C1CCCC1)C1CCN(C(=O)CNC(=O)/C=C/c2ccccc2)CC1 CHEMBL1495950 Potency 29.9 nM
CC(=O)c1ccc2c(c1)C1C(Cl)C(Sc3ccccc3[N+](=O)[O-])CC1C(c1ccccc1[N+](=O)[O-])N2 CHEMBL1517128 Potency 31.6 nM
Cn1c(SCC(=O)Nc2ccc3c(c2)OCCO3)nnc1-c1ccco1 CHEMBL1458854 Potency 31.6 nM
Sc1nnc(SCc2ccccc2Cl)c2nc[nH]c12 CHEMBL1332182 Potency 31.6 nM
CCOC(=O)c1ccc(NC(S)=NCCCN2CCCC2=O)cc1 CHEMBL1594660 Potency 31.6 nM
COc1cccc(-c2nccc(NCc3cccs3)n2)c1 CHEMBL1436355 Potency 31.6 nM
Cn1nnc(NC(=O)c2ccc([N+](=O)[O-])cc2Cl)n1 CHEMBL1490127 Potency 31.6 nM
COC(=O)c1nnc(C(=O)N(C)Cc2ccccc2)c2[nH]c3ccccc3c12 CHEMBL1442357 Potency 31.6 nM
C=CS(=O)(=O)c1ccc(Oc2ccc(S(=O)(=O)C=C)cc2)cc1 CHEMBL1454183 Potency 31.6 nM
CC1(C)CC(=O)C(C2(O)C(=O)N(Cc3ccccc3)c3ccccc32)CO1 CHEMBL1523545 Potency 31.6 nM
NCCCCCc1nnc(SCC(=O)c2ccc(Cl)cc2)o1 CHEMBL1506836 Potency 31.6 nM
COc1ccc(CN=C(S)Nc2ccc(F)c(Cl)c2)cc1 CHEMBL1310988 Potency 31.6 nM
Cc1cc(C(=O)CCl)c(C)n1CCc1ccccc1 CHEMBL1525315 Potency 31.6 nM
Cc1ccccc1C(=O)N1CCN(c2ccc(NC(=O)c3ccco3)cc2Cl)CC1 CHEMBL1588024 Potency 31.6 nM
CCC(=O)N(C)/C=C1\Sc2ccccc2C1=O CHEMBL1392924 Potency 31.6 nM
CC1(C#N)CCN(c2c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc3ccsc23)CC1 CHEMBL4209516 IC50 32.0 nM
CC1(C#N)CCN(c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4213542 IC50 33.0 nM
O=C(c1cnc2ccc(F)cc2c1N1CCC2(CCCCC2)C1)N1CCN(C(=O)C2CC2)CC1 CHEMBL4215656 IC50 35.0 nM
COc1cc2ncc(C(=O)N3CCN(C(=O)C4CC4)CC3)c(N3CCC4(CC3)OCCO4)c2cc1OC CHEMBL4211021 IC50 35.0 nM
Cc1ccc2ncc(C(=O)N3CCN(C(=O)C4CC4)CC3)c(N3CCC4(CC3)OCCO4)c2c1 CHEMBL4215984 IC50 35.0 nM
Cc1cccc2c1N(CCCOc1ccccc1)C(=O)C2=O CHEMBL1567384 Potency 35.5 nM
O=C(CCN1CCCC1Cc1ccccc1)c1ccc2c(c1)OCCO2 CHEMBL1379139 Potency 35.5 nM
COc1cccc(-c2ccc3ncnc(NCCN4CCOCC4)c3c2)c1 CHEMBL1322216 Potency 35.5 nM
CC1(C)Oc2ccc(NC(=O)C3COc4ccccc4O3)cc2O1 CHEMBL1579773 Potency 35.5 nM
O=C1CCCC2=C1C(c1ccccc1)C1C(=O)c3ccccc3C1=N2 CHEMBL1371186 Potency 35.5 nM
COc1ccc(/N=C2/C(=O)N3CCCc4cccc2c43)cc1 CHEMBL3207319 Potency 35.5 nM
COc1ccc(Oc2ccc(N/C=C/C(=O)C(C)(C)C)cc2)cc1 CHEMBL1425141 Potency 35.5 nM
Cc1ccc(NC(=O)NCCCc2ccccc2)cc1 CHEMBL1490884 Potency 35.5 nM
N#CC1=C2SCC(O)(c3ccccc3)N2C(=O)CC1c1cccs1 CHEMBL1347618 Potency 35.5 nM
O=C(CCl)N(c1ccccc1)C1CCCCC1 CHEMBL1387688 Potency 35.5 nM
COc1ccc(O)c(/C=N/N=C2/C(=O)Nc3ccccc32)c1 CHEMBL3191877 Potency 35.5 nM
N#CC1=C(N)OC2=C(CC/C2=C\c2ccc(F)cc2)C1c1ccc(F)cc1 CHEMBL1550933 Potency 37.7 nM
C=CS(=O)(=O)N1CCN(c2c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4213628 IC50 38.0 nM
CC1CN(C(=O)C(C)Sc2nc3ccccc3s2)CC(C)O1 CHEMBL1340444 Potency 39.8 nM
Cc1ccccc1-c1nccc(NCc2cccs2)n1 CHEMBL1370189 Potency 39.8 nM
COc1cc(C(=O)CCN2CCC(c3ccccc3)C2)cc(OC)c1OC CHEMBL1300980 Potency 39.8 nM
CC(=O)NC1C(=O)N(CC(C)C)c2ccccc21 CHEMBL1610946 Potency 39.8 nM
O=C(Cc1ccccc1)Nc1cccc([N+](=O)[O-])c1 CHEMBL213884 Potency 39.8 nM
O=C(NCCc1ccccc1)/C(=C\c1ccc([N+](=O)[O-])cc1)NC(=O)c1ccccc1 CHEMBL1363067 Potency 39.8 nM
COc1ccc(Cl)cc1NC(=O)CN(C(=O)c1ccco1)C1CCCCC1 CHEMBL1520645 Potency 39.8 nM
COC(=O)CNC(=O)[C@@]1(C)C=C[C@@H](Cc2ccccc2)N1C(=O)OC CHEMBL1573319 Potency 39.8 nM
CC(C)OC(=O)C1C(=O)CC(C)(O)C(C(=O)OC(C)C)C1c1cccc([N+](=O)[O-])c1 CHEMBL1374328 Potency 39.8 nM
CCc1cc2ccc(C)cc2nc1SCC(=O)Nc1cnc(O)nc1O CHEMBL1334596 Potency 39.8 nM
COc1ccc(COc2ccccc2C(=O)Nc2ccccn2)cc1[N+](=O)[O-] CHEMBL1390441 Potency 39.8 nM
CN(C)CCC(=O)c1cccc(Br)c1 CHEMBL1585823 Potency 39.8 nM
CCCCCN1C(=O)C(=O)c2ccccc21 CHEMBL3128209 IC50 40.0 nM
S=C(SSC(=S)N1CCOCC1)N1CCOCC1 CHEMBL121556 IC50 40.0 nM
CC(C)CCn1c(CN2CCN(C(=O)C3CC3)CC2)nc2c1c(=O)n(C)c(=O)n2C CHEMBL4215649 IC50 41.0 nM
O=C(c1cnc2ccc(F)cc2c1N1CCC2(CCCO2)CC1)N1CCN(C(=O)C2CC2)CC1 CHEMBL4206479 IC50 43.0 nM
COc1ccc(CNC(=O)c2c(-c3cc(Cl)c(OC)c(Cl)c3)noc2C)cc1 CHEMBL1369838 Potency 44.7 nM
O=C(CCl)N(c1ccccc1)c1ccccc1 CHEMBL1603760 Potency 44.7 nM
O=C(CN1CCN(C(=O)c2cccs2)CC1)NC1CCCCC1 CHEMBL1578786 Potency 44.7 nM
COC(=O)c1ccc(Oc2nc3c(c(=O)n(C)c(=O)n3C)n2CCC(C)C)cc1 CHEMBL1609093 Potency 44.7 nM
Cn1ccnc1SCCNC(=O)CCc1nnc(CCCCc2ccccc2)o1 CHEMBL1422389 Potency 44.7 nM
CC1CC2(CCCCC2)N2C(=O)C(=O)c3cccc1c32 CHEMBL1403270 Potency 44.7 nM
CCCCOc1ccc(C(=O)CCN2CCCCC2)cc1 CHEMBL1200478 Potency 44.7 nM
Cc1ccc(N(CC(=O)Nc2ccc3c(c2)OCCO3)S(C)(=O)=O)cc1 CHEMBL1403111 Potency 44.7 nM
CC(=O)Nc1ccc(C(=O)CCl)cc1 CHEMBL1408847 Potency 44.7 nM
O=[N+]([O-])c1ccc(N/N=C2/CCCCC2c2ccccn2)cc1 CHEMBL3199587 Potency 44.7 nM
CC(Oc1ccccc1)C(=O)N=Nc1c(O)[nH]c2ccc(Br)cc12 CHEMBL1602104 Potency 44.7 nM
C=CCn1c(SCC#N)nc2sc(CC)cc2c1=O CHEMBL1549138 Potency 44.7 nM
Cc1cccc(C)c1NC(=O)COc1ccc2c(C)c(Cc3ccccc3)c(=O)oc2c1C CHEMBL1349928 Potency 44.7 nM
C=CCOC(=O)C1=C(C)N=C(S)NC1/C=C/c1ccccc1 CHEMBL1587090 Potency 44.7 nM
O=C(c1cnc2ccc(F)cc2c1N1C[C@H]2CCCC[C@H]2C1)N1CCN(C(=O)C2CC2)CC1 CHEMBL4210664 IC50 45.0 nM
CC1(C)CCN(c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4213440 IC50 46.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC3(CC2)Cc2ccccc2C3=O)CC1 CHEMBL4214148 IC50 47.0 nM
O=C1C(=O)N(CCCc2ccccc2)c2ccccc21 CHEMBL1328547 IC50 50.0 nM
O=C(c1cnc2cc(F)c(F)cc2c1N1CCC2(CC1)OCCO2)N1CCN(C(=O)C2CC2)CC1 CHEMBL4218736 IC50 50.0 nM
S=C(SSC(=S)N1CCCCC1)N1CCCCC1 CHEMBL121516 IC50 50.0 nM
O=C(NC(c1ccccc1)c1ccccc1)c1nc[nH]c1C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 CHEMBL1555433 Potency 50.1 nM
COc1ccc(C2Nc3ccccc3C(=O)N2c2ccccc2)cc1Cn1cc([N+](=O)[O-])cn1 CHEMBL1457777 Potency 50.1 nM
O=C(CSC1=NCCN1)NC1CCCCCC1 CHEMBL1422728 Potency 50.1 nM
O=C(CN1CCCCC1)NC(=O)NC1CCCC1 CHEMBL1459867 Potency 50.1 nM
COc1ccc(CCn2c(=S)[nH]c3cc(C(=O)NCc4ccco4)ccc3c2=O)cc1OC CHEMBL1500167 Potency 50.1 nM
COCc1cc(O)nc(SCCS(=O)(=O)c2ccc(Cl)cc2Cl)n1 CHEMBL1518475 Potency 50.1 nM
O=C(Nc1nc[nH]n1)c1ccc(S(=O)(=O)N2CCOCC2)cc1 CHEMBL1412551 Potency 50.1 nM
COc1ccc(Nc2cc(C(=O)NCc3ccco3)c3ccccc3n2)cc1 CHEMBL1560232 Potency 50.1 nM
O=C(NC1CCCCC1)c1ccc(S(=O)(=O)c2ccccc2Cl)c([N+](=O)[O-])c1 CHEMBL1464834 Potency 50.1 nM
O=C1C(=O)N(Cc2cccc([N+](=O)[O-])c2)c2ccccc21 CHEMBL1543770 Potency 50.1 nM
NNC(=O)C(=O)Nc1ccc(O)cc1 CHEMBL1597788 Potency 50.1 nM
C#CCNC(=O)c1ccc(OCc2ccccc2)cc1Cl CHEMBL1559489 Potency 50.1 nM
COc1cc(CNCCO)cc(Cl)c1OCc1ccc(Cl)cc1Cl CHEMBL1542560 Potency 50.1 nM
O=C1C(=O)N(Cc2ccc(Cl)c(Cl)c2)c2ccccc21 CHEMBL375126 Potency 50.1 nM
CCOC(=O)c1c(C)nn(S(=O)(=O)c2ccc(Br)cc2)c1NCc1ccccc1 CHEMBL1585036 Potency 50.1 nM
COc1ccc(NS(=O)(=O)c2ccc3[nH]c(COc4ccc(Cl)c(C)c4)nc3c2)cc1 CHEMBL1404507 Potency 50.1 nM
CCOc1ccc(CN(C)C(=O)CCl)cc1 CHEMBL1444473 Potency 50.1 nM
COc1ccc(-c2cc(C(=O)O)no2)cc1 CHEMBL1413079 Potency 50.1 nM
Cc1cc(=O)oc2cc(OCC(=O)OCC(=O)Nc3ccc4ccccc4c3)ccc12 CHEMBL1367342 Potency 50.1 nM
COc1ccc(OC)c(N2C(=O)NC(=O)/C(=C/c3ccc([N+](=O)[O-])s3)C2=O)c1 CHEMBL1509826 Potency 50.1 nM
CC(C)Sc1nnc(NC(=O)C2CC2)s1 CHEMBL1431427 Potency 50.1 nM
N#CNC(=N)Nc1ccc(Cl)cc1 CHEMBL1329926 Potency 56.2 nM
O=C(Cn1cnc2c(nnn2Cc2ccccc2F)c1=O)OCc1ccccc1 CHEMBL1576567 Potency 56.2 nM
O=C(NCC1CCCO1)C(c1ccc(F)cc1)N(Cc1ccc(F)cc1)C(=O)Cn1nnc(-c2cccs2)n1 CHEMBL1568396 Potency 56.2 nM
COc1ccccc1/N=C/C1=C(O)OC2(CCCCC2)OC1=O CHEMBL3210648 Potency 56.2 nM
CC(C)(C)c1ccc(S(=O)(=O)/C=C\C#N)cc1 CHEMBL1441136 Potency 56.2 nM
CC(C)(C)Nc1oc(-c2ccccc2)nc1-c1cccc2ccccc12 CHEMBL1593183 Potency 56.2 nM
O=[N+]([O-])c1cc(C(F)(F)F)cc([N+](=O)[O-])c1NCCN=C(S)Nc1cccc(F)c1 CHEMBL1610987 Potency 56.2 nM
Cc1ccc(S(=O)(=O)/C=C/C#N)cc1 CHEMBL403183 Potency 56.2 nM
O=Cc1ccc(N2CCCCCC2)cc1 CHEMBL1345502 Potency 56.2 nM
CCOc1ccc(NC(=O)N2CCC(NC(=O)C(Cc3ccc(OC)c(OC)c3)NC(C)=O)CC2)cc1 CHEMBL1428570 Potency 56.2 nM
O=c1c2ccccc2sn1-c1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1 CHEMBL1371792 Potency 56.2 nM
c1ccc(CCNc2ncnc3scc(C4COc5ccccc5O4)c23)cc1 CHEMBL1408029 Potency 56.2 nM
O=S(=O)(c1cccc(Cl)c1)N1CCCC1 CHEMBL1334769 Potency 56.2 nM
Cc1cc(C)nc(SCc2cc(=O)c(OC(=O)c3cccc([N+](=O)[O-])c3)co2)n1 CHEMBL1589651 Potency 56.2 nM
CCCOc1ccc(C(=O)CCN2CCCCC2)cc1 CHEMBL1588844 Potency 56.2 nM
CCN(CC)c1ccc(C=O)cc1 CHEMBL3416563 IC50 57.0 nM
CC(C)c1ccc(C(=O)N2CCN(CCC(=O)N(Cc3ccccc3C(F)(F)F)c3cn(C)c(=O)n(C)c3=O)CC2)cc1 CHEMBL5191150 IC50 59.0 nM
CCOc1ccc(C(=O)N2CCCN(C(=O)c3ccc(OCC)cc3)CC2)cc1 CHEMBL1418894 Potency 59.7 nM
CC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc21 CHEMBL284328 Potency 59.7 nM
Cc1ccc(NC(=S)N(CCN2CCCCC2)Cc2ccco2)cc1Cl CHEMBL1479092 Potency 59.7 nM
O=C1C(=O)N(Cc2ccccc2)c2ccc(Cl)cc21 CHEMBL336693 IC50 60.0 nM
CC1(C#N)CCN(c2c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc3sccc23)CC1 CHEMBL4205142 IC50 60.0 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC3(CC2)CC(=O)c2ccccc23)CC1 CHEMBL4218564 IC50 61.0 nM
C=CCN1C(=O)/C(=N/n2cnnc2)c2ccccc21 CHEMBL1983168 Potency 63.1 nM
O=C(CCl)N(c1ccccc1)C1CCS(=O)(=O)C1 CHEMBL1418980 Potency 63.1 nM
CC(C)OC(=O)CN1C(=O)C(=O)c2ccccc21 CHEMBL1299266 Potency 63.1 nM
C/C(N)=C(/C#N)C(=O)COC(=O)CCSc1ccccc1Cl CHEMBL3191686 Potency 63.1 nM
CCOC(=O)c1ccc(N2C(=O)C=CC2=O)cc1 CHEMBL1519298 Potency 63.1 nM
CC1(C)CC(=O)CC(C2(O)C(=O)N(Cc3ccccc3)c3ccccc32)O1 CHEMBL1599808 Potency 63.1 nM
CCOC(=O)CNC(=O)c1cc(C)oc1C CHEMBL1335623 Potency 63.1 nM
COc1ccc(C(=O)CCN2CCCCCC2)cc1 CHEMBL1580341 Potency 63.1 nM
O=Nc1ccc(Nc2ccccc2)cc1 CHEMBL1600998 Potency 63.1 nM
CN(c1ccccc1)S(=O)(=O)c1ccc(NC(=O)c2ccco2)cc1 CHEMBL1326280 Potency 63.1 nM
O=C(Nc1ccncc1)c1ccc(S(=O)(=O)Nc2ccccc2)cc1 CHEMBL1601582 Potency 63.1 nM
Cn1cc(C(=O)CCl)c2ccccc21 CHEMBL1544997 Potency 63.1 nM
COc1ccc(OC)c(-n2nnnc2SCC(=O)Nc2ccc3c(c2)OCCO3)c1 CHEMBL1570057 Potency 63.1 nM
CCOc1ccc(C(=O)CCN2CCCCCC2)cc1 CHEMBL1472513 Potency 63.1 nM
CC1(C#N)CCN(c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3sccc23)CC1 CHEMBL4210039 IC50 64.0 nM
O=C(c1cnc2ccc(F)cc2c1N1CCC2(CC1)CC2)N1CCN(C(=O)C2CC2)CC1 CHEMBL4218305 IC50 67.0 nM
O=C(c1cnc2ccccc2c1N1CCC2(CC1)OCCO2)N1CCN(C(=O)C2CC2)CC1 CHEMBL4209073 IC50 68.0 nM
CC(Sc1nc2nn(C3COC3)cc2c(=O)n1-c1ccccc1)c1ccccn1 CHEMBL4849586 IC50 68.0 nM
O=C1C(=O)N(C/C=C/c2ccccc2)c2ccccc21 CHEMBL1453099 IC50 70.0 nM
O=C1C(=O)N(CCc2ccccc2)c2ccccc21 CHEMBL3128205 IC50 70.0 nM
C[C@@H](Sc1nc2c(cnn2C)c(=O)n1-c1ccccc1)c1ccccc1 CHEMBL4876602 IC50 70.0 nM
C/C=C/C(=O)Nc1nnc(-c2ccccc2C)s1 CHEMBL1301143 Potency 70.8 nM
C[C@]12C/C(=C/O)C(=O)C[C@@H]1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(C)O CHEMBL1200585 Potency 70.8 nM
CSc1ccccc1NC(=O)CN(Cc1ccccc1)S(C)(=O)=O CHEMBL1488143 Potency 70.8 nM
O=C(O)[C@H]1C[C@@H](CP(=O)(O)O)CCN1 CHEMBL279731 Potency 70.8 nM
COC(C)=O CHEMBL14079 Potency 70.8 nM
O=C(c1ccccc1)N1CCN(c2ccc(NCc3ccc4c(c3)OCO4)cc2)CC1 CHEMBL1301760 Potency 70.8 nM
Nc1nnnn1/N=C/c1ccc(N2CCCCC2)c([N+](=O)[O-])c1 CHEMBL3198547 Potency 70.8 nM
O=C(CC1(O)C(=O)N(Cc2ccccc2)c2ccccc21)c1ccncc1 CHEMBL1504793 Potency 70.8 nM
O=C(NNc1ncnc2c1cnn2-c1ccccc1)c1ccco1 CHEMBL1464995 Potency 70.8 nM
C/C(CC(=O)Nc1ccc(Cl)cc1Cl)=N\NC(N)=S CHEMBL3194801 Potency 70.8 nM
CC(C)(C)C(=O)Nc1ncccc1C(O)c1cccc(C(F)(F)F)c1 CHEMBL1493914 Potency 70.8 nM
O=C(CCN1C[C@H]2CC[C@H](CC2)C1)c1cccs1 CHEMBL1412225 Potency 70.8 nM
Cc1c(C2CCN(CCc3ccccc3)CC2)noc1-c1ccc(Cl)cc1 CHEMBL444309 Potency 70.8 nM
C[N+](C)(C)CCC(=O)c1cccc2ccccc12 CHEMBL1255936 Potency 70.8 nM
CCOC(=O)c1sc2ncn(/N=C/c3cccnc3)c(=O)c2c1C CHEMBL3199357 Potency 70.8 nM
Cc1ccc(OCCCN2C(=O)C(=O)c3cccc(C)c32)cc1 CHEMBL1505211 Potency 70.8 nM
O=C(Cn1sc2ccccc2c1=O)NC12CC3CC(CC(C3)C1)C2 CHEMBL1471698 Potency 70.8 nM
CC(C)Oc1ccc(C(=O)CCN2CCCCC2)cc1 CHEMBL1508519 Potency 70.8 nM
CN1C(=O)/C(=C\c2ccc(N3CCCCCC3)cc2)C(=O)NC1=S CHEMBL1311010 Potency 70.8 nM
COc1ccc(OC)c(N/C(C)=C/C(=O)c2ccc(Br)cc2)c1 CHEMBL1380428 Potency 75.1 nM
Cc1ccc2c(c1)NC(=O)C(CC(=O)NCCCN1CCN(c3cc(Cl)ccc3C)CC1)O2 CHEMBL1607067 Potency 75.1 nM
CCOC(=O)c1cnc2nc(C)nn2c1N CHEMBL1502326 Potency 75.1 nM
CCOC(=O)c1noc(C)c1C(=O)Nc1nccs1 CHEMBL1520488 Potency 75.1 nM
COc1ccc(CCNS(=O)(=O)c2ccc(F)cc2)cc1OC CHEMBL1443937 Potency 75.1 nM
O=C(CCl)N(Cc1ccccc1)c1ccccc1 CHEMBL1567635 Potency 79.4 nM
O=C(CCl)c1ccccc1 CHEMBL105712 Potency 79.4 nM
Cc1cccc(N2CCN(C(=O)Cc3cn(C)c4ccccc34)CC2)c1C CHEMBL1541016 Potency 79.4 nM
O=C(Nc1nc2ccccc2n1Cc1ccccc1)c1ccc(COc2ccccc2[N+](=O)[O-])o1 CHEMBL1382389 Potency 79.4 nM
Cc1cc2oc(=O)cc(Cn3ncc(Cl)c(Cl)c3=O)c2cc1Cl CHEMBL1421328 Potency 79.4 nM
COc1ccc(-n2c(=S)[nH]c3cc(C(=O)NCc4ccco4)ccc3c2=O)cc1OC CHEMBL1382897 Potency 79.4 nM
CN1[C@@H]2CC[C@H]1CC(OC(=O)[C@@H](CO)c1ccccc1)C2 CHEMBL1363694 Potency 79.4 nM
Cc1cc(C)c2[nH]c(O)c(N=NC(S)=NCC3CCCO3)c2c1 CHEMBL1521485 Potency 79.4 nM
COc1ccc(NC(=O)CSc2ncccc2C(=O)OC(C)C)cc1OC CHEMBL1414585 Potency 79.4 nM
Cc1ccccc1-n1nnnc1SCCCC(=O)c1ccc(F)cc1 CHEMBL1580377 Potency 79.4 nM
CCOC(=O)c1c(NC(=O)CC2S/C(=N\C)N(C)C2=O)sc(C)c1C CHEMBL3210059 Potency 79.4 nM
COc1ccc2cc(CN(CCc3ccccc3)Cc3nnnn3Cc3ccco3)c(O)nc2c1 CHEMBL1481244 Potency 79.4 nM
O=C(NCC(=O)N(c1cccnc1)C(C(=O)NC1CCCC1)c1ccco1)c1cccs1 CHEMBL1601761 Potency 79.4 nM
CC(C)(C)c1cc(O)ccc1O CHEMBL242080 Potency 79.4 nM
CCOC(=O)N1CCN(Cc2nc3c(c(=O)n(C)c(=O)n3C)n2Cc2cccc(C)c2)CC1 CHEMBL1377847 Potency 79.4 nM
COc1ccccc1CN(CC(=O)NCc1ccc2c(c1)OCO2)C(=O)c1ccc2c(c1)OCCO2 CHEMBL1387451 Potency 79.4 nM
CCCCOc1ccc(C(=O)N2CC(C)OC(C)C2)cc1 CHEMBL1413179 Potency 79.4 nM
O=C(C1=C(O)/C(=C/c2ccc(O)cc2)CCC1)C(F)(F)F CHEMBL1407002 Potency 79.4 nM
Cc1ccc2c(c1)C(=O)C(=O)N2CC(=O)OC(C)C CHEMBL1547730 Potency 79.4 nM
CS(=O)(=O)N1CCN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(CO)(c3ccccc3)CC2)CC1 CHEMBL4213430 IC50 80.0 nM
Cn1ncc2c(=O)n(-c3ccccc3)c(SCc3cccc(F)c3)nc21 CHEMBL4213331 IC50 80.0 nM
O=c1c2cn(C3COC3)nc2nc(SCc2cccc(F)c2)n1-c1ccccc1 CHEMBL4210115 IC50 80.0 nM
C[C@H]1CN(C(=O)c2cnc3ccc(F)cc3c2N2CCC(C)(C#N)CC2)CCN1S(C)(=O)=O CHEMBL4217372 IC50 86.0 nM
CCC1(CC)CCN(c2c(C(=O)N3CCN(C(=O)C4CC4)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4218082 IC50 86.0 nM
CS(=O)(=O)CCN(Cc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1)C(=O)CCC(=O)OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1 CHEMBL5094282 IC50 86.42 nM
Cn1ncc2c(N3CCC(C)(C#N)CC3)c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc21 CHEMBL4216949 IC50 87.0 nM
CC1(C#N)CCN(c2c(C(=O)N3CCC(C(=O)C4CC4)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4212955 IC50 89.0 nM
CCC(CC)C(=O)c1c[nH]c(C(=O)OC)c1 CHEMBL1449031 Potency 89.1 nM
CC(C)Oc1ccc(Br)cc1/C=N\NC(N)=S CHEMBL1978383 Potency 89.1 nM
COc1ccccc1N1CCN(c2ccc(Cl)nn2)CC1 CHEMBL1398753 Potency 89.1 nM
O=C(/C=C/Nc1ccc(Nc2ccccc2)cc1)c1cccs1 CHEMBL1604303 Potency 89.1 nM
Cc1cc(C)c2c(-n3cccc3)c(C(=O)NNS(=O)(=O)c3ccc(Br)cc3)sc2n1 CHEMBL1340013 Potency 89.1 nM
COc1ccc(S(=O)(=O)Nc2ccc(S(=O)(=O)N3CCCC3)cc2)cc1 CHEMBL1399022 Potency 89.1 nM
CCC(OC(=O)CN1C(=O)C(=O)c2ccccc21)C(=O)Nc1ccc(S(N)(=O)=O)cc1 CHEMBL1526775 Potency 89.1 nM
O=C(CCN1CCOCC1)c1ccc(Cl)cc1 CHEMBL234180 Potency 89.1 nM
Cc1ccccc1NS(=O)(=O)c1ccc(OCC(=O)NCc2cccnc2)cc1 CHEMBL1302359 Potency 89.1 nM
Cc1onc(-c2ccccc2)c1CNS(=O)(=O)c1cccc(Cl)c1 CHEMBL1333479 Potency 89.1 nM
CC(C)CC(=O)N1CCN(Cc2ccccc2[N+](=O)[O-])CC1 CHEMBL1577509 Potency 89.1 nM
COc1cccc2cc(C(=O)CC3(O)C(=O)N(Cc4ccccc4)c4ccccc43)c(=O)oc12 CHEMBL1596513 Potency 89.1 nM
COc1ccc(OC)c(/N=C/C2=C(O)OC3(CCCCC3)OC2=O)c1 CHEMBL3209691 Potency 89.1 nM
CCOC(=O)N1CCN(CCC(=O)c2ccc(Cl)cc2)CC1 CHEMBL1543548 Potency 89.1 nM
O=C(CN1C(=O)C(=O)c2ccccc21)NCCc1ccccc1 CHEMBL1493615 Potency 89.1 nM
O=C(COC(=O)CN1C(=O)C(=O)c2ccccc21)OCN1C(=O)c2ccccc2C1=O CHEMBL1330829 Potency 89.1 nM
COc1cc(/C=C(\NC(C)=O)C(=O)Nc2cccc(O)c2)ccc1OC(C)=O CHEMBL1370893 Potency 89.1 nM
CSC1(SC2=NCCN2)SC2(NCCN2)S1 CHEMBL1335862 Potency 89.1 nM
C[N+](C)(C)CCC(=O)c1cccc2ccccc12 CHEMBL1358898 Potency 89.1 nM
O=C(O)c1cc(-c2ccc(/C=C3/SC(=S)N(Cc4ccccc4)C3=O)o2)ccc1Cl CHEMBL1546414 Potency 89.1 nM
Cc1cccc2c1N(CCCOc1ccc(C(C)(C)C)cc1)C(=O)C2=O CHEMBL1522544 Potency 89.1 nM
CCN(CC)C(=S)SSC(=S)N(CC)CC CHEMBL964 Potency 89.1 nM
Cc1ccc(NC(=O)CSc2ncc(-c3ccccc3)n2C(=O)c2ccccc2)cc1 CHEMBL1526076 Potency 89.1 nM
Cc1cc(/C=C2\SC(=S)N(Cc3ccco3)C2=O)c(C)n1-c1ccccc1 CHEMBL1511037 Potency 89.1 nM
Cc1ccsc1C(=O)C1CCCN(CCO)C1 CHEMBL1313809 Potency 89.1 nM
O=S(=O)(c1cc(Cl)ccc1Cl)N1CCCC1 CHEMBL1391090 Potency 89.1 nM
O=C(OCn1ncc(Br)c(Br)c1=O)c1ccc(F)cc1 CHEMBL1485010 Potency 89.1 nM
O=C1/C(=N/n2cnnc2)c2ccccc2N1Cc1ccccc1 CHEMBL3209672 Potency 89.1 nM
COc1cccc(-c2csc(N3CCN(C(S)=Nc4ccc(Cl)cc4)CC3)n2)c1 CHEMBL1445687 Potency 89.1 nM
O=C1C(=O)N(CCc2ccccc2)c2ccc(Cl)cc21 CHEMBL3128206 IC50 90.0 nM
CC(Sc1nc2nn(C3(C)COC3)cc2c(=O)n1-c1ccccc1)c1ccccc1 CHEMBL4861872 IC50 93.0 nM
CC1(C#N)CCN(c2c(C(=O)N3CCN(S(C)(=O)=O)CC3)cnc3ccc(F)cc23)CC1 CHEMBL4216370 IC50 94.0 nM
CC(Sc1nc2c(cnn2C)c(=O)n1-c1ccccc1)c1cncnc1 CHEMBL4849624 IC50 94.0 nM
COc1ccc(-n2c(=S)[nH]c3cc(C(=O)Nc4cc(OC)c(OC)c(OC)c4)ccc3c2=O)c(OC)c1 CHEMBL1481464 Potency 94.6 nM
CC(C)CCn1c(CN2CCC(C(N)=O)CC2)nc2c1c(=O)n(C)c(=O)n2C CHEMBL3416554 Ki 96.0 nM