O=C(OCC#CCSc1nnc(-c2cccc3ccccc23)o1)c1ccco1 CHEMBL1270410 Potency 2.2 nM
COc1ccc(C(=O)OCC#CCSc2nnc(-c3cccc4ccccc34)o2)cc1 CHEMBL1269896 Potency 3.2 nM
CC(=O)c1c(N2CCC(C(N)=O)CC2)nc(=S)n(-c2ccccc2)c1C CHEMBL1331888 Potency 3.2 nM
O=C(Nc1nc[nH]n1)c1ccc(Cl)c(S(=O)(=O)Nc2ccc(Cl)cc2)c1 CHEMBL1339179 Potency 6.3 nM
O=c1cc(-c2ccccc2)oc2cc(O)c(O)cc12 CHEMBL300814 Potency 7.9 nM
Cc1cc(C)nc(NC2=NCC(=O)N2c2ccccc2)n1 CHEMBL1430985 Potency 8.9 nM
COc1cc(CC(=O)Nc2ncc(C)s2)cc(OC)c1OC CHEMBL1578957 Potency 25.1 nM
O=C(CSCC(=O)Nc1ccccc1)N/N=C/c1c(O)ccc2ccccc12 CHEMBL3191182 Potency 25.1 nM
COCC(C)NC(=O)NC1(C(F)(F)F)Oc2ccc(Cl)cc2O1 CHEMBL1308557 Potency 31.6 nM
COCCNC(=O)NC1(C(F)(F)F)Oc2ccc(Cl)cc2O1 CHEMBL1531156 Potency 35.5 nM
Oc1ccc(C2=Nn3c(nnc3-c3ccco3)SC2)cc1O CHEMBL1543965 Potency 39.8 nM
COc1ccc(-n2nnnc2SCC(=O)c2ccc(O)c(O)c2)cc1 CHEMBL254255 Potency 44.7 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3nc4c(ccc5ccccc54)s3)cc2)c1O CHEMBL4869861 IC50 50.0 nM
Cc1ccc(S(=O)(=O)c2cc3c(=O)n4ccccc4nc3n(CC3CCCO3)c2=N)cc1C CHEMBL1549610 Potency 56.2 nM
CCn1c(SCC(=O)c2ccc(O)c(O)c2)nnc1-c1ccccc1 CHEMBL1334710 Potency 56.2 nM
CC1(CCc2ccccc2)N=C(S)N(c2ccc(Cl)cc2)N1 CHEMBL1601374 Potency 70.8 nM
C=CCN1C(=O)/C(=C\c2ccco2)C(C(=O)OC)=C1C CHEMBL1407135 Potency 70.8 nM
COc1ccccc1-n1c(O)cc(=O)nc1SCC(=O)Nc1ccc(C)cc1 CHEMBL1447541 Potency 79.4 nM
Cc1oc2c(O)c(O)ccc2c(=O)c1-c1cnn(-c2ccccc2)c1 CHEMBL1560296 Potency 89.1 nM
O=C1CCN(c2ccccc2)N1 CHEMBL7660 IC50 100.0 nM
CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 CHEMBL52 IC50 110.0 nM
COc1cccc(-n2c(SCc3cc(=O)oc4cc(O)c(O)cc34)nc3ccccc3c2=O)c1 CHEMBL1499658 Potency 125.9 nM
O=C(NC1(C(F)(F)F)Oc2ccc(Cl)cc2O1)N1CCC2(CC1)OCCO2 CHEMBL1605701 Potency 125.9 nM
CC(C)c1ccc(O)c(=O)c(O)c1 CHEMBL1324842 Potency 141.3 nM
O=[N+]([O-])/C=C/c1cn(Cc2ccc(Cl)cc2)c2ccccc12 CHEMBL1566706 Potency 141.3 nM
O=C(O)c1cc(C(=O)C(=O)c2cc(C(=O)O)c(O)c3ccccc23)c2ccccc2c1O CHEMBL222808 IC50 150.0 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3cccc(C(C)C)c3)cc2)c1O CHEMBL3113197 IC50 160.0 nM
Nc1nc(-c2ccc(Br)s2)c(Br)s1 CHEMBL1595951 Potency 177.8 nM
O=c1c(-c2ccc3c(c2)OCCO3)coc2cc(O)cc(O)c12 CHEMBL1365850 Potency 177.8 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3nc(-c4ccccc4)cs3)cc2)c1O CHEMBL3113193 IC50 180.0 nM
Oc1c(Cl)cc(C(c2cc(Cl)c(O)c(Cl)c2)C(c2cc(Cl)c(O)c(Cl)c2)c2cc(Cl)c(O)c(Cl)c2)cc1Cl CHEMBL238624 IC50 210.0 nM
CC(C)=CCc1c(O)cc(-c2cc3ccc(O)cc3o2)cc1O CHEMBL2018876 IC50 210.0 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3nc4ccc(F)cc4s3)cc2)c1O CHEMBL3113198 IC50 220.0 nM
COc1ccc(C(=O)NNc2ccccc2)cc1OC CHEMBL1566678 Potency 223.9 nM
CCOC(=O)C(C)Oc1ccccc1C1NC(=O)NC(C)=C1C(=O)Nc1ccc(C)c(C)c1 CHEMBL1540789 Potency 223.9 nM
N#C/C(=N\Nc1cc(Cl)cc(Cl)c1)c1nnc2n1CCCCC2 CHEMBL3197254 Potency 223.9 nM
Cc1nnc(NC(=O)c2ccc3ccccc3c2)o1 CHEMBL1312186 Potency 223.9 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3nc4c(C)cccc4s3)cc2)c1O CHEMBL3113169 IC50 240.0 nM
O=C(N/N=C/c1cc(Br)ccc1O)C(=O)Nc1ccccc1OC(F)(F)C(F)F CHEMBL3190293 Potency 251.2 nM
O=C(N/N=C/c1c(O)ccc2ccccc12)c1cccc(C(F)(F)F)c1 CHEMBL1988042 Potency 251.2 nM
COC1=CC2=C[C@@H]3[C@@]4(C)CCCC(C)(C)[C@@H]4CC[C@]3(C)OC2=CC1=O CHEMBL463805 IC50 260.0 nM
COc1ccc2nc(NS(=O)(=O)c3ccc(NCc4cccc(OC)c4O)cc3)sc2c1 CHEMBL3113192 IC50 260.0 nM
COc1cc2c(cc1O)O[C@@]1(C)CC[C@H]3C(C)(C)CCC[C@]3(C)[C@H]1[C@@H]2OC CHEMBL459185 IC50 280.0 nM
CC1(CCc2ccccc2)N=C(S)N(c2ccccc2)N1 CHEMBL1402668 Potency 281.8 nM
O=c1cc(-c2ccccc2Cl)oc2c(NS(=O)(=O)c3cc(Cl)cc(Cl)c3O)ccc(O)c12 CHEMBL223453 Potency 281.8 nM
O=C(COc1ccccc1C(=O)N/N=C\c1ccc(O)c(O)c1)N/N=C/c1ccc(O)c(O)c1 CHEMBL1979849 Potency 281.8 nM
COc1ccc2c(c1)OCC(Cc1ccc(O)c(OC)c1)C2=O CHEMBL1356623 Potency 281.8 nM
COc1ccc(-c2noc(CSc3nnc(CCc4ccccc4)n3-c3ccccc3)n2)cc1OC CHEMBL1333962 Potency 281.8 nM
O=C(/C(=N/N=C/c1ccc(O)c(O)c1O)c1ccccc1)c1ccccc1 CHEMBL1995550 Potency 281.8 nM
C=CCc1cccc(C2Nc3ccccc3C(=O)N2O)c1O CHEMBL1448849 Potency 316.2 nM
O=C(N/N=C/c1ccc(O)c(O)c1)C1c2ccccc2Oc2ccccc21 CHEMBL3199413 Potency 316.2 nM
C/C(=N\c1ccccc1)C1=C(O)OCC1=O CHEMBL3210691 Potency 316.2 nM
COc1ccc(-n2c(COc3cccc(C)c3)nnc2SCC(=O)NCc2ccco2)cc1 CHEMBL1465924 Potency 316.2 nM
CC(=O)c1cc2c(O)c(O)ccc2o1 CHEMBL1370800 Potency 316.2 nM
Cc1cc2c(C(C)C)c(O)c(O)c(C=O)c2c(O)c1-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O CHEMBL51483 Potency 316.2 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3ccc4ccccc4c3)cc2)c1O CHEMBL3113180 IC50 330.0 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3nc4ccccc4s3)cc2)c1O CHEMBL3113165 IC50 340.0 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3cccs3)cc2)c1O CHEMBL3113168 IC50 350.0 nM
COc1c(O)c(O)cc2c1oc1c3cc(C)ccc3oc(=O)c21 CHEMBL1532186 Potency 354.8 nM
C[C@H](Cc1cc(O)c(O)cc1[N+](=O)[O-])[C@@H](C)Cc1cc(O)c(O)cc1[N+](=O)[O-] CHEMBL92359 IC50 360.0 nM
C[C@H](Cc1cc(O)c(O)cc1Cl)[C@@H](C)Cc1cc(O)c(O)cc1Cl CHEMBL314941 IC50 360.0 nM
CCC(=O)NC(c1cccs1)c1cc(Cl)c2cccnc2c1O CHEMBL1405150 IC50 380.0 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3cccc(C(C)(C)C)c3)cc2)c1O CHEMBL3113191 IC50 390.0 nM
CNC(=S)N/N=C/c1cc(Br)cc(Br)c1O CHEMBL3196548 Potency 398.1 nM
CCCC(O)(CCC)C(=O)NNc1ccccc1 CHEMBL1486778 Potency 398.1 nM
O=C(N/C=C/c1ccc(O)c(Br)c1)/C(Cc1cc(Br)c(O)c(Oc2c(Br)cc(C/C(=N\O)C(=O)NCCc3ccc(O)c(Br)c3)cc2Br)c1)=N/O CHEMBL186752 IC50 400.0 nM
CNC(=O)N(O)CC1=Cc2cc(Oc3ccc(F)cc3)ccc2OC1 CHEMBL333219 IC50 410.0 nM
Oc1c(Br)cc(Br)cc1Oc1c(O)c(Br)c(Br)c(Br)c1Br CHEMBL150098 IC50 410.0 nM
C[C@H](Cc1cc(O)c(O)cc1Br)[C@@H](C)Cc1cc(O)c(O)cc1Br CHEMBL89283 IC50 430.0 nM
CC(=O)NC(c1cccs1)c1cc(Br)c2cccnc2c1O CHEMBL1573436 IC50 430.0 nM
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL50 IC50 440.0 nM
O=C(Oc1ccc(Cl)c2cccnc12)c1cccc([N+](=O)[O-])c1 CHEMBL1492376 Potency 446.7 nM
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCc1ccc(O)c(O)c1 CHEMBL138921 Potency 446.7 nM
CCn1c(SCC(=O)c2ccc(O)c(O)c2)nnc1-c1ccccc1OC CHEMBL1310309 Potency 446.7 nM
O=c1c(-c2ccc(Cl)cc2)coc2c(O)c(O)ccc12 CHEMBL241814 IC50 480.0 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3cnc4ccccc4c3)cc2)c1O CHEMBL3113176 IC50 480.0 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3ccccc3)cc2)c1O CHEMBL3113178 IC50 500.0 nM
O=c1c2ccccc2sn1-c1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCCC1 CHEMBL1338317 Potency 501.2 nM
Cc1ccc(-c2oc3ccccc3c(=O)c2O)cc1 CHEMBL273103 Potency 501.2 nM
O=C(/C=C/c1ccccc1)c1cc(Br)ccc(=O)c1O CHEMBL1418885 Potency 501.2 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3cccc4ccccc34)cc2)c1O CHEMBL3113179 IC50 510.0 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3nc4ccccc4o3)cc2)c1O CHEMBL3113166 Ki 530.0 nM
CCN(c1ccccc1)S(=O)(=O)c1ccc(NCC2COc3ccccc3O2)nc1 CHEMBL1422284 Potency 562.3 nM
CC(Sc1nc2cc([N+](=O)[O-])ccc2n1-c1ccc(F)cc1)C(=O)NCc1ccc2c(c1)OCO2 CHEMBL1339033 Potency 562.3 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3nc4ccccc4[nH]3)cc2)c1O CHEMBL3113167 IC50 570.0 nM
COc1c(O)cc2oc3cc(O)c(CC=C(C)C)c(O)c3c(=O)c2c1CC=C(C)C CHEMBL323197 IC50 580.0 nM
O=c1c(-c2cccc(C(F)(F)F)c2)coc2c(O)c(O)ccc12 CHEMBL238844 IC50 620.0 nM
Cc1cc(O)c(-c2cc(O)c(C)cc2O)cc1O CHEMBL1527565 Potency 631.0 nM
CC(C)C(=O)NC(c1cccs1)c1cc([N+](=O)[O-])c2cccnc2c1O CHEMBL1377316 Potency 631.0 nM
Cc1cc(SCC(=O)N/N=C/c2ccc(O)cc2O)c(C)cc1Br CHEMBL3189613 Potency 631.0 nM
O=c1c(O)c(-c2ccc3c(c2)OCO3)oc2ccccc12 CHEMBL1523114 Potency 631.0 nM
CCCC(=O)NC(c1cccs1)c1cc([N+](=O)[O-])c2cccnc2c1O CHEMBL1546767 Potency 631.0 nM
COc1cc(SC#N)ccc1/N=C/c1c(C)nn(-c2cccc3ccccc23)c1O CHEMBL3191089 Potency 631.0 nM
NC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 CHEMBL116719 IC50 640.0 nM
Oc1c(Br)c(Br)c(Br)c(Br)c1Oc1ccc(Br)cc1Br CHEMBL362761 IC50 700.0 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3cccc4ccncc34)cc2)c1O CHEMBL3113177 IC50 700.0 nM
Cc1c(/N=C2\SCC(=O)N2c2c(C)n(C)n(-c3ccccc3)c2=O)c(=O)n(-c2ccccc2)n1C CHEMBL3207580 Potency 707.9 nM
Cc1cc(C2CCCCC2)n(O)c(=O)c1 CHEMBL242580 Potency 707.9 nM
C/C(=N\NC(=O)c1cc2c(s1)CCC(C)C2)c1ccncc1 CHEMBL3211218 Potency 707.9 nM
Oc1c(I)cc(Cl)c2cccnc12 CHEMBL497 Potency 707.9 nM
COc1ccc(OC)c(CCNC(=O)Cn2sc3nc(C)cc(C)c3c2=O)c1 CHEMBL1510394 Potency 707.9 nM
Cc1ccc(C)c(N/N=C2\CCCNC2=O)c1 CHEMBL3208287 Potency 707.9 nM
Oc1c(Cl)cc(Cl)cc1Sc1cc(Cl)cc(Cl)c1O CHEMBL290106 Potency 707.9 nM
CCc1cccc2c(C(=O)CSc3nncn3-c3ccccc3OC)c[nH]c12 CHEMBL1393573 Potency 707.9 nM
COc1cccc(CNc2ccc(S(=O)(=O)Nc3cccc(C4CCN(C(=O)OC(C)(C)C)CC4)c3)cc2)c1O CHEMBL3113195 IC50 760.0 nM
O=c1c(-c2cccc(Cl)c2)coc2c(O)c(O)ccc12 CHEMBL241815 IC50 780.0 nM
COc1cc2c(cc1O)O[C@@]1(C)CC[C@H]3C(C)(C)CCC[C@]3(C)C1=C2 CHEMBL463806 IC50 780.0 nM
O=C(O)c1cc2c(cc1S(=O)(=O)O)[C@H]1[C@@H](C3[C@H]2[C@@]2(Cl)C(Cl)=C(Cl)[C@@]3(Cl)C2(Cl)Cl)[C@]2(Cl)C(Cl)=C(Cl)[C@]1(Cl)C2(Cl)Cl CHEMBL2373284 Potency 794.3 nM
O=C1c2ccccc2NC(c2ccc(Cl)cc2Cl)N1O CHEMBL1417610 Potency 794.3 nM
CCOc1ccc(N/N=C(/C#N)C(N)=O)cc1 CHEMBL3193407 Potency 794.3 nM
CCn1c(SCC(=O)c2ccc(O)c(O)c2)nnc1-c1ccc(C)cc1 CHEMBL1350596 Potency 794.3 nM
Cc1ccc(CN=C(S)Nc2ccc(C)c([N+](=O)[O-])c2)cc1 CHEMBL1602768 Potency 794.3 nM
CCN=c1ccc(Br)cc(C(=O)/C=C/c2ccc3c(c2)OCO3)c1O CHEMBL1340514 Potency 794.3 nM
CCC(=O)NC(c1cccs1)c1cc([N+](=O)[O-])c2cccnc2c1O CHEMBL1369893 IC50 800.0 nM
O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12 CHEMBL8260 IC50 860.0 nM
O=c1cc(CO)oc(C(Nc2ccccn2)c2ccc(C(F)(F)F)cc2)c1O CHEMBL1568397 Potency 891.3 nM
O=C(N/N=C/c1ccc(O)c(O)c1)/C(O)=C\C1=NC2(CCCC2)Cc2ccccc21 CHEMBL3195564 Potency 891.3 nM
CCNc1oc(-c2cccc3ccccc23)nc1C#N CHEMBL1571456 Potency 891.3 nM
O=C(CSc1nc(-c2ccccc2O)n[nH]1)N1CCCc2ccccc21 CHEMBL1495091 Potency 891.3 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1ccccc1O CHEMBL1399595 Potency 891.3 nM
CCOC(=O)COc1cc(Br)c(/C=N/Nc2ccccc2)cc1OC CHEMBL1986032 Potency 891.3 nM
COc1ccccc1-c1nnc2n1N=C(c1ccc(O)c(O)c1)CS2 CHEMBL1393480 Potency 891.3 nM
O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)ccc12 CHEMBL31574 IC50 950.0 nM