O=c1cc(-c2ccccc2)c2ccc(Sc3cc(F)cc(C(O)(C(F)(F)F)C(F)(F)F)c3)cc2o1 CHEMBL377821 IC50 0.5 nM
O=c1cc(-c2ccc(F)cc2)c2cc(Sc3cc(F)cc(C(O)(C(F)(F)F)C(F)(F)F)c3)ccc2o1 CHEMBL205800 IC50 0.5 nM
O=c1cc(-c2ccoc2)c2ccc(Sc3cc(F)cc(C(O)(C(F)(F)F)C(F)(F)F)c3)cc2o1 CHEMBL377094 IC50 0.8 nM
CCC(O)(CC)c1cc(F)cc(OCc2ccc3c(-c4ccoc4)cc(=O)oc3c2)c1 CHEMBL204365 IC50 0.9 nM
CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12 CHEMBL16596 IC50 1.6 nM
O=c1cc(-c2ccc(F)cc2)c2ccc(COc3cc(F)cc(C(O)(C(F)(F)F)C(F)(F)F)c3)cc2o1 CHEMBL205189 IC50 1.9 nM
N#Cc1cc(-c2ccoc2)c2ccc(COc3cc(F)cc([C@]4(O)C[C@H]5CO[C@@H](C4)O5)c3)cc2n1 CHEMBL207057 IC50 2.3 nM
CCC(O)(c1cc(F)cc(OCc2ccc3c(-c4ccc(F)cc4)cc(=O)oc3c2)c1)c1nccs1 CHEMBL205222 IC50 2.7 nM
COC1(c2cc(F)cc(OCc3cc(-c4ccccc4)n(-c4ccc(S(C)(=O)=O)cc4)n3)c2)CCOCC1 CHEMBL423638 IC50 3.0 nM
CC1Cc2c(OCc3ccc4ccccc4n3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL50170 IC50 3.0 nM
CC1Cc2c(CCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)Cc2nnn[nH]2)n3Cc2ccc(Cl)cc2)S1 CHEMBL81812 IC50 3.0 nM
O=C(O)CCC[C@H](O)/C=C\C=C\C=C\[C@H](O)C/C=C\CCCCC(F)(F)F CHEMBL194522 EC50 3.0 nM
O=c1cc(-c2ccoc2)c2ccc(COc3cc(F)cc([C@]4(O)C[C@H]5CO[C@@H](C4)O5)c3)cc2o1 CHEMBL207109 IC50 3.0 nM
CCC(O)(c1cc(F)cc(OCc2ccc3c(-c4ccoc4)cc(=O)oc3c2)c1)c1ccccn1 CHEMBL204633 IC50 3.7 nM
O=c1cc(-c2ccccc2)c2ccc(COc3cc(F)cc([C@]4(O)C[C@H]5CO[C@@H](C4)O5)c3)cc2o1 CHEMBL204781 IC50 3.7 nM
O=C(Nc1cccc2ccccc12)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 CHEMBL3238463 IC50 4.0 nM
O=c1cc(-c2ccc(Cl)cc2)c2ccc(Sc3cc(F)cc(C(O)(C(F)(F)F)C(F)(F)F)c3)cc2o1 CHEMBL206632 IC50 4.3 nM
Cc1cccc(OC(=O)c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2)c1 CHEMBL3238207 IC50 6.0 nM
CCCc1cc(F)c2oc(Cc3ccc(OC)cc3)c(C)c2c1O CHEMBL280055 IC50 7.0 nM
O=C(O)CSC(CCCc1ccc(Cl)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1 CHEMBL32842 IC50 7.0 nM
Oc1ccc(-c2ccc3ccccc3c2)cc1O CHEMBL5398068 IC50 7.0 nM
Oc1ccc(-c2cccc3c2sc2ccccc23)cc1O CHEMBL5421129 IC50 7.0 nM
CCC(O)(c1cn(Cc2ccc3c(-c4ccccc4)c(C(=O)OC)sc3c2)nn1)C(F)(F)F CHEMBL1290649 IC50 7.9 nM
CC(C)(C)Sc1c(CC(C)(C)C(=O)[O-])n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12 CHEMBL313489 IC50 8.0 nM
C/C(=N\O[C@H](c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O CHEMBL2093045 IC50 8.0 nM
CCC(OCCc1c2c3c(c(OCc4ccc(-c5ccccc5)cn4)ccc3n1Cc1ccc(Cl)cc1)CC(C)S2)C(=O)O CHEMBL275634 IC50 8.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)Cc2nnn[nH]2)n3Cc2ccc(Cl)cc2)S1 CHEMBL275887 IC50 8.0 nM
COC(=O)CNC(=O)C(=O)c1cn(S(=O)(=O)c2ccc(C)cc2)c2ccccc12 CHEMBL3113612 IC50 8.0 nM
Oc1ccc(-c2cccc3c2SC2C=CC=CC2S3)cc1O CHEMBL5395696 IC50 8.0 nM
Cc1ccc(S(=O)(=O)n2cc(C(=O)C(=O)NCC(=O)O)c3ccccc32)cc1 CHEMBL3113617 Ki 8.4 nM
C/C(=N\OC(CCCc1ccc(F)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1)C(=O)O CHEMBL349526 IC50 9.0 nM
Cc1ccc(S(=O)(=O)n2cc(C(=O)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C(=O)O)c3ccccc32)cc1 CHEMBL3113618 Ki 9.9 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(COc2ccccc2CC(=O)O)n3Cc2cccc(Cl)c2)S1 CHEMBL140915 IC50 10.0 nM
COC1(c2cccc(OCc3ccc4ccccc4c3)c2)CCOCC1 CHEMBL88084 IC50 10.0 nM
CC(C)(CC(O/N=C/C(=O)O)c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccccc1 CHEMBL159516 IC50 10.0 nM
CCCCC(CCCC)C(O/N=C/C(=O)O)c1ccc(OCc2ccc3ccccc3n2)cc1 CHEMBL159297 IC50 10.0 nM
C/C(=N\OCC#N)c1ccc(Sc2cc([C@@]3(C)COC(C)(C)O3)cs2)cc1 CHEMBL129970 IC50 10.0 nM
Cc1cccc(NC(=O)c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2)c1 CHEMBL3238465 IC50 10.0 nM
COc1ccc(-c2sc(-c3ccc(Cl)cc3)nc2O)cc1 CHEMBL3353726 IC50 10.0 nM
CCOc1ccc2ccccc2c1-c1ccc(O)c(O)c1 CHEMBL5413117 IC50 10.0 nM
Oc1ccc(-c2c3ccccc3cc3ccccc23)cc1O CHEMBL5401317 IC50 10.0 nM
CCCc1cc(Cl)c2oc(Cc3ccc(OC)cc3)c(C)c2c1O CHEMBL17815 IC50 11.0 nM
CC1Cc2c(SCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)Cc2nnn[nH]2)n3Cc2ccc(Cl)cc2)S1 CHEMBL94307 IC50 11.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)CC(=O)NS(C)(=O)=O)n3Cc2ccc(Cl)cc2)S1 CHEMBL96253 IC50 11.0 nM
CCC(O)(c1cn(Cc2ccc3c(-c4ccccc4)c(C(C)=O)sc3c2)nn1)C(F)(F)F CHEMBL1289215 IC50 11.0 nM
O=c1cc(-c2ccc(F)cc2)c2ccc(COc3cc(F)cc([C@]4(O)C[C@H]5CO[C@@H](C4)O5)c3)cc2o1 CHEMBL204890 IC50 11.6 nM
CCCc1cc(C)c2oc(Cc3ccc(OC)cc3)c(C)c2c1O CHEMBL18394 IC50 12.0 nM
COc1ccc(COc2ccc3c4c2CC(C)Sc4c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)nc1 CHEMBL96611 IC50 12.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)CC(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL96844 IC50 12.0 nM
C=C1CCCC2C1(C)CCC(C)C2(C)CCC1=CC(=O)OC1O CHEMBL5290007 IC50 12.73 nM
CCCc1cc(Cl)c2oc(Cc3ccc(OC)cc3OC)c(C)c2c1O CHEMBL18946 IC50 13.0 nM
C/C(=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCCC1)C(=O)O CHEMBL422010 IC50 13.0 nM
COc1cc(/C=C/c2cc(/C=C/c3ccc(O)c(OC)c3)[nH]n2)ccc1O CHEMBL180239 IC50 13.0 nM
COc1cc(/C=C/c2cc(-c3ccc(O)c(OC)c3)[nH]n2)ccc1O CHEMBL2413471 IC50 13.0 nM
COc1cc(/C=C/c2cc(/C=C/c3cc(CC=C(C)C)c(O)c(OC)c3)[nH]n2)cc(CC=C(C)C)c1O CHEMBL3290441 IC50 13.0 nM
CC(=O)N(O)C/C=C/c1cccc(Oc2ccccc2)c1 CHEMBL314360 IC50 13.0 nM
COC1(c2cccc(COc3ccc4c(-c5ccccc5)c5c(cc4c3)C(=O)OC5)c2)CCOCC1 CHEMBL129292 IC50 14.0 nM
CCCCC(CCCC)C(O/N=C(\C)C(=O)O)c1ccc(OCc2ccc3ccccc3n2)cc1 CHEMBL355374 IC50 14.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2nc3cc(F)ccc3s2)cc1Cl)C1CCCCC1 CHEMBL348398 IC50 14.0 nM
C/C(=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1Cl)C1CCCCC1)C(=O)O CHEMBL350807 IC50 14.0 nM
COC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)C(=O)c1cn(S(=O)(=O)c2ccc(C)cc2)c2ccccc12 CHEMBL3113613 IC50 14.0 nM
CC1=CCCC2C1(C)CCC(C)C2(C)CCC1=CC(=O)OC1O CHEMBL5284118 IC50 14.38 nM
C/C(=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O CHEMBL159721 IC50 15.0 nM
N#Cc1cc(-c2ccoc2)c2ccc(OCc3cccc(C4(O)CCOCC4)n3)cc2c1 CHEMBL99217 IC50 15.0 nM
C/C(=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCC1)C(=O)O CHEMBL161720 IC50 16.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(-c3ccccc3)cn2)S1 CHEMBL92469 IC50 16.0 nM
C=C1C(O)CCC2C1(C)CCC(C)C2(C)CCC1=CC(=O)OC1O CHEMBL5267222 IC50 16.54 nM
C/C(CCCCCC(=O)O)=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 CHEMBL163164 IC50 17.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 CHEMBL160054 IC50 17.0 nM
C/C(CCC(=O)O)=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 CHEMBL159376 IC50 17.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCCC1 CHEMBL346031 IC50 18.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)CCC(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL96353 IC50 19.0 nM
CCC(O)(c1cn(Cc2ccc3c(-c4ccccc4)c(CO)sc3c2)nn1)C(F)(F)F CHEMBL1289093 IC50 19.0 nM
c1ccc2c(c1)Nc1ccccc1O2 CHEMBL276850 IC50 20.0 nM
C=CCc1cc(Cl)c2oc(Cc3ccc(OC)cc3)c(C)c2c1O CHEMBL278034 IC50 20.0 nM
CN(O)C(=O)CCSc1nc2cc(Cl)ccc2s1 CHEMBL110928 EC50 20.0 nM
O=C(O)c1ccc(CN(Cc2cccc(F)c2)c2ccc(OCc3ccc4ccccc4n3)cc2)cc1 CHEMBL310584 IC50 20.0 nM
CN(O)C(=O)NCCSc1nc2cc(Cl)ccc2s1 CHEMBL320274 EC50 20.0 nM
CCCc1cc(Cl)c2oc(Cc3ccc(OC)cc3)c(CCC)c2c1O CHEMBL18989 IC50 20.0 nM
COC1(c2cccc(OCc3ccc4c(-c5ccccc5)c5c(cc4c3)C(=O)OC5)c2)CCOCC1 CHEMBL150169 IC50 20.0 nM
COC1(c2cc(F)cc(OCc3ccc4c(ccc(=O)n4C)c3)c2)CCOCC1 CHEMBL20403 IC50 20.0 nM
COC1(c2cc(Sc3ccc4c(c3)CCC(=O)N4C)sc2C)CCOCC1 CHEMBL341040 IC50 20.0 nM
COC1(c2cc(OCc3ccc4c(ccc(=O)n4C)c3)cc(F)c2C)CCOCC1 CHEMBL129341 IC50 20.0 nM
C/C(CCC(=O)O)=N/OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 CHEMBL2110176 IC50 20.0 nM
COC1(c2cc(Sc3ccc(/C(C)=N/O)cc3)cc(F)c2C)CCOCC1 CHEMBL125792 IC50 20.0 nM
O=C(O)/C(CCc1ccccc1)=N/OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 CHEMBL161965 IC50 20.0 nM
Cc1cc(C(O/N=C/C(=O)O)C2CCCCC2)ccc1OCc1ccc2ccccc2n1 CHEMBL160015 IC50 20.0 nM
C/C(=N\OC(c1ccc(OCc2ccc3ccccc3n2)c(C)c1)C1CCCCC1)C(=O)O CHEMBL161132 IC50 20.0 nM
C/C(=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1C2CC3CC(C2)CC1C3)C(=O)O CHEMBL348939 IC50 20.0 nM
C/C(=N\OCC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O CHEMBL348996 IC50 20.0 nM
COc1cc(OCc2ccc3ccccc3n2)ccc1C(O/N=C/C(=O)O)C1CCCCC1 CHEMBL159537 IC50 20.0 nM
C/C(=N\OC(c1ccc(OCc2nc(-c3ccccc3)cs2)cc1)C1CCCCC1)C(=O)O CHEMBL161830 IC50 20.0 nM
C/C(=N\OC(c1ccc(OCc2ccc3cc(F)ccc3n2)cc1)C1CCCCC1)C(=O)O CHEMBL159817 IC50 20.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCOC(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL13931 IC50 20.0 nM
N#Cc1cc(-c2ccoc2)c2ccc(OCc3cccc(C4(O)CC5COC(C4)O5)n3)cc2c1 CHEMBL278293 IC50 20.0 nM
CCC(OCCc1c2c3c(c(OCc4ccc(-c5ccccc5)cn4)ccc3n1Cc1ccc(Cl)cc1)CC(C)S2)C(=O)NS(C)(=O)=O CHEMBL16285 IC50 20.0 nM
CC1Cc2c(OCc3cc4ccccc4cn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL430487 IC50 20.0 nM
O=C1/C(=C/c2ccc(Cl)cc2)N=C(c2ccccc2)N1c1ccc(-c2nc3ccccc3o2)cc1 CHEMBL5280920 IC50 20.0 nM
Oc1ccc(-c2ccc(Cl)cc2)cc1O CHEMBL5418840 IC50 20.0 nM
Oc1ccc(-c2cccc(Cl)c2)cc1O CHEMBL5413658 IC50 20.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2nc(-c3ccccc3)cs2)cc1)C1CCCCC1 CHEMBL162667 IC50 21.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1C2CC3CC(C2)CC1C3 CHEMBL163544 IC50 21.0 nM
O=C(O)/C(=N/OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)c1cccs1 CHEMBL350823 IC50 21.0 nM
CC[C@](O)(c1cn(Cc2ccc3c(-c4ccc(F)cc4)c(C(N)=O)sc3c2)nn1)C(F)(F)F CHEMBL1289558 IC50 21.0 nM
O=C1OCc2c1cc1cc(OCc3ccc(-c4ccccc4)cn3)ccc1c2-c1ccccc1 CHEMBL305306 IC50 22.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2nc3ccccc3s2)cc1Br)C1CCCCC1 CHEMBL163806 IC50 22.0 nM
C/C(=N\OC(CC(C)(C)c1ccccc1)c1ccc(OCc2ccc3ccccc3n2)cc1)C(=O)O CHEMBL351319 IC50 22.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCOC(C)C(=O)NS(C)(=O)=O)n3Cc2ccc(Cl)cc2)S1 CHEMBL277746 IC50 22.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL295761 IC50 22.0 nM
COC1CC(O)(c2cccc(COc3ccc4c(-c5ccccc5)c5c(cc4c3)C(=O)OC5)c2)CCO1 CHEMBL131135 IC50 23.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCOc2ccccc2CC(=O)O)n3Cc2cccc(F)c2)S1 CHEMBL141645 IC50 23.0 nM
O=C(O)/C(=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)c1cccs1 CHEMBL2110173 IC50 23.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3CCCc2ccccc2)S1 CHEMBL275474 IC50 23.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL96423 IC50 23.0 nM
CCNC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 CHEMBL120582 IC50 24.0 nM
CCCC1Oc2c(C)c(C)c(O)c(C)c2S1 CHEMBL290579 IC50 25.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2cnc3ccccc3n2)cc1)C1CCCCC1 CHEMBL163758 IC50 25.0 nM
CC(Cc1ccc(O)c(O)c1)C(C)Cc1ccc(O)c(O)c1 CHEMBL52 IC50 25.0 nM
O=C1OCc2c1cc1cc(OCc3cccc(C4(O)CCOCC4)c3)ccc1c2-c1ccoc1 CHEMBL129018 IC50 26.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(COc2ccccc2CC(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL341562 IC50 26.0 nM
CCCc1cc(Cl)c2oc(Cc3ccc(Cl)cc3)c(C)c2c1O CHEMBL18694 IC50 26.0 nM
O=C1OCc2c1cc1cc(OCc3cccc(C4(O)CCOCC4)c3)ccc1c2-c1ccsc1 CHEMBL339993 IC50 27.0 nM
C/C(=N\OC(c1ccc(OCc2ccc3ccccc3n2)c(Cl)c1)C1CCCCC1)C(=O)O CHEMBL163222 IC50 27.0 nM
O=C(O)/C=N/OC(CC1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1 CHEMBL159765 IC50 27.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2nc3cccnc3s2)cc1)C1CCCCC1 CHEMBL350839 IC50 27.0 nM
CC1Cc2c(OCc3cccc(-c4ccccc4)n3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL317482 IC50 27.0 nM
N#Cc1cc(-c2ccoc2)c2ccc(COc3cc(F)cc(C4(O)CC5COC(C4)O5)c3)cc2n1 CHEMBL22789 IC50 27.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2nc3ccccc3s2)cc1Cl)C1CCCCC1 CHEMBL163392 IC50 28.0 nM
C/C(=N\OC(c1ccc(OCc2nc3ccccc3s2)cc1Cl)C1CCCCC1)C(=O)O CHEMBL351626 IC50 28.0 nM
COc1ccc(Cn2c(CC(C)(C)C(=O)O)c3c4c(c(OCc5ccc(-c6ccccc6)cn5)ccc42)CC(C)S3)cc1 CHEMBL329217 IC50 28.0 nM
CC1Cc2c(OCc3cccs3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL96169 IC50 28.0 nM
COc1cccc(Cn2c(CC(C)(C)C(=O)O)c3c4c(c(OCc5ccc(-c6ccccc6)cn5)ccc42)CC(C)S3)c1 CHEMBL96767 IC50 28.0 nM
CC[C@](O)(c1cn(Cc2ccc3c(-c4ccccc4)c(C(N)=O)sc3c2)nn1)C(F)(F)F CHEMBL1289447 IC50 28.0 nM
CCCCCCCCCCCCCc1c(O)c(O)cc(OC)c1OC CHEMBL4085835 IC50 28.0 nM
C/C(=N\OC(CC1CCCCC1)c1ccc(OCc2ccc3ccccc3n2)cc1)C(=O)O CHEMBL159302 IC50 29.0 nM
CCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O CHEMBL3416359 IC50 29.0 nM
CC(c1ccccc1)N(O)C(=O)Cc1ccc(OCc2ccccc2)cc1 CHEMBL444315 IC50 30.0 nM
N#Cc1cc(-c2ccoc2)c2ccc(OCc3cccc(C4(O)CCOCC4)c3)cc2c1 CHEMBL99469 IC50 30.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CSc2ccccc2C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL342680 IC50 30.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCSc2ccccc2C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL337576 IC50 30.0 nM
CCCc1cc(Cl)c2oc(Cc3ccccc3)c(C)c2c1O CHEMBL18820 IC50 30.0 nM
COC1(c2cccc(OCc3ccc4c(ccc(=O)n4C)c3)c2)CCOCC1 CHEMBL316091 IC50 30.0 nM
C/C(=N\OC(Cc1ccccc1)c1ccc(OCc2ccc3ccccc3n2)cc1)C(=O)O CHEMBL346110 IC50 30.0 nM
CC/C(=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O CHEMBL161584 IC50 30.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCC1 CHEMBL159988 IC50 30.0 nM
COC1(c2cc(Sc3ccc(N(C)C(C)=O)cc3)cc(F)c2C)CCOCC1 CHEMBL340420 IC50 30.0 nM
C/C(=N\OCC#N)c1ccc(Sc2ncc([C@@]3(C)COC(C)(C)O3)s2)cc1 CHEMBL554262 IC50 30.0 nM
Cc1ccc2nc(-c3ccc(OCc4ccccc4)cc3)c(NC3CCCCC3)n2c1 CHEMBL1958141 IC50 30.0 nM
O=C(Nc1ccc(-c2csc(Nc3ccc(O)cc3)n2)cc1)C12CC3CC(CC(C3)C1)C2 CHEMBL3099680 IC50 30.0 nM
O=C(Nc1cccc(-c2ccccc2)c1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 CHEMBL3238471 IC50 30.0 nM
COc1ccc(Cc2sc(-c3ccc(Cl)cc3)nc2O)cc1 CHEMBL3353725 IC50 30.0 nM
Oc1ccc(Nc2nc(-c3ccc(Cl)cc3)cs2)cc1 CHEMBL1076555 IC50 30.0 nM
Oc1ccc(Nc2nc(-c3ccc(Cl)c(Cl)c3)cs2)cc1 CHEMBL1081482 IC50 30.0 nM
CCOc1ccc(-c2csc(Nc3ccc(O)cc3)n2)cc1 CHEMBL3318370 IC50 30.0 nM
Oc1ccccc1Nc1nc(-c2ccc(Cl)cc2)cs1 CHEMBL3318371 IC50 30.0 nM
CCCCCCCCCCCc1c(O)c(O)cc(OC)c1OC CHEMBL4093584 IC50 30.0 nM
CC1(C)Cc2c(-c3ccccc3)c(-c3occ4ccccc34)c(CC(=O)O)n2C1 CHEMBL5271431 IC50 30.0 nM
Oc1ccc(-c2cc3ccccc3o2)cc1O CHEMBL5425532 IC50 30.0 nM
CCCCCCCCCCCCc1c(O)c(O)cc(OC)c1OC CHEMBL4103758 IC50 30.0 nM
O=C1C(Cc2ccc[nH]2)c2ccccc2N1c1c(Cl)cccc1Cl CHEMBL5404346 IC50 30.0 nM
CC1=CCCC2C1(C)CCC(C)C2(C)CC/C(=C\C(=O)O)CO CHEMBL5283932 IC50 30.51 nM
CCCc1ccc2oc(Cc3ccc(OC)cc3)c(C)c2c1O CHEMBL18050 IC50 31.0 nM
O=C(O)c1ccc(/C=N/OC(c2ccc(OCc3ccc4ccccc4n3)cc2)C2CCCCC2)cc1 CHEMBL163931 IC50 31.0 nM
O=C(O)/C(=N/OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)c1ccccc1 CHEMBL422536 IC50 31.0 nM
CCOC(=O)c1c(CCc2cccc(Cl)c2)[nH]c2c1cc(O)c1ccccc12 CHEMBL482849 IC50 31.0 nM
CC[C@](O)(c1cn(Cc2ccc3c(-c4cccc(F)c4)c(C(N)=O)sc3c2)nn1)C(F)(F)F CHEMBL1289557 IC50 31.0 nM
CC(=NOC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O CHEMBL2110175 IC50 32.0 nM
C/C(=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1)c1cccs1)C(=O)O CHEMBL159535 IC50 33.0 nM
C/C(=N\OC(c1cc2cc(OCc3ccc4ccccc4n3)ccc2s1)C1CCCCC1)C(=O)O CHEMBL160086 IC50 33.0 nM
CCC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL96424 IC50 33.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3CC2CCCCC2)S1 CHEMBL319661 IC50 33.0 nM
O=C(Nc1cccc(Cl)c1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 CHEMBL3238466 IC50 33.0 nM
CCCNC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 CHEMBL120347 IC50 34.0 nM
C/C(=N\O[C@H](c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)[O-] CHEMBL2110174 IC50 34.0 nM
COc1ccc(NC(=O)c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2)cc1 CHEMBL3238468 IC50 34.0 nM
CCOC(=O)/C=C/c1ccc2c(c1)Nc1ccccc1O2 CHEMBL273714 IC50 35.0 nM
O=C(O)/C(Cc1ccccc1)=N/OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 CHEMBL161612 IC50 35.0 nM
CC(C)c1ccc(-c2csc(COc3ccc(C(O/N=C/C(=O)O)C4CCCCC4)cc3)n2)cc1 CHEMBL423605 IC50 35.0 nM
CC1Cc2c(OCc3ccccn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL96412 IC50 35.0 nM
CNC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 CHEMBL118929 IC50 36.0 nM
N#Cc1cc(-c2ccoc2)c2ccc(OCc3cccc(C4(O)CC5COC(C4)O5)n3)cc2n1 CHEMBL22751 IC50 36.0 nM
C=CCNC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 CHEMBL120454 IC50 37.0 nM
NC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 CHEMBL116719 IC50 37.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL96342 IC50 37.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCC(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL328967 IC50 38.0 nM
CC(=O)N(O)C(=O)/C=C/c1cccc(Oc2ccccc2)c1 CHEMBL529218 IC50 38.0 nM
CN(O)C(=O)CCSc1nc2ccccc2s1 CHEMBL108204 EC50 39.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCOc2ccccc2CC(=O)O)n3Cc2cccc(Cl)c2)S1 CHEMBL140204 IC50 40.0 nM
COC1(c2cc(F)cc(OCc3ccc4c(c3)sc(=O)n4C)c2)CCOCC1 CHEMBL330120 IC50 40.0 nM
CC(/C=C/C(=O)O)=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 CHEMBL163434 IC50 40.0 nM
C/C(=N\OC(c1cc2ccc(OCc3ccc4ccccc4n3)cc2s1)C1CCCCC1)C(=O)O CHEMBL164251 IC50 40.0 nM
CN1C(=O)COc2ccc(Sc3cc(C4(C)COC(C)(C)O4)cs3)cc21 CHEMBL339228 IC50 40.0 nM
COC1(c2cc(Sc3ccc4c(c3)OCC(=O)N4C)cc(F)c2C)CCOCC1 CHEMBL129698 IC50 40.0 nM
CC(=O)N(C)c1ccc(Sc2cc([C@@]3(C)COC(C)(C)O3)cs2)cc1 CHEMBL130996 IC50 40.0 nM
C/C(=N\O)c1ccc(Sc2cc([C@@]3(C)COC(C)(C)O3)cs2)cc1 CHEMBL131014 IC50 40.0 nM
C/C(=N\O)c1ccc(Sc2cc(C3(C)COC(C)(C)O3)cs2)cc1 CHEMBL128464 IC50 40.0 nM
COC1(c2cc(S(=O)(=O)c3ccc4c(ccc(=O)n4C)c3)ccc2C)CCOCC1 CHEMBL129863 IC50 40.0 nM
CC[C@@H](CSCc1c2c3c(c(OCc4ccc(-c5ccccc5)cn4)ccc3n1Cc1ccc(Cl)cc1)CC(C)S2)C(=O)O CHEMBL278632 IC50 40.0 nM
COc1cc(/C=C2\CCn3c2nc2ccccc2c3=O)cc(OC)c1O CHEMBL518103 IC50 40.0 nM
CCC(O)(c1cn(Cc2ccc3c(-c4ccccc4)csc3c2)nn1)C(F)(F)F CHEMBL1290766 IC50 40.0 nM
Cc1ccc2nc(-c3cccc(OCc4ccccc4)c3)c(NC3CCCCC3)n2c1 CHEMBL1958143 IC50 40.0 nM
CCCCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O CHEMBL3416361 IC50 40.0 nM
CCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O CHEMBL3416357 IC50 40.0 nM
C/C(=C\CC/C(C)=C/CC[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1)CCC=C(CO)CO CHEMBL4847874 IC50 40.0 nM
COC1c2c(-c3ccccc3)c(-c3ccc(Cl)cc3)c(CC(=O)O)n2CC1(C)C CHEMBL5268642 IC50 40.0 nM
Oc1ccc(-c2ccc3c(c2)OCCO3)cc1O CHEMBL5441068 IC50 40.0 nM
NC(=O)N(O)CC1=Cc2cc(Oc3ccc(F)cc3)ccc2OC1 CHEMBL330889 IC50 42.0 nM
COc1cccc(-c2c3c(cc4ccccc24)C(=O)OC3)c1 CHEMBL63662 IC50 42.0 nM
CCCCc1ccc(COc2ccc3c4c2CC(C)Sc4c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)nc1 CHEMBL329529 IC50 42.0 nM
O=C(O)[C@@H](c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCCC1 CHEMBL5275767 IC50 42.0 nM
O=C(O)/C(Cc1ccc(O)cc1)=N/OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 CHEMBL349246 IC50 43.0 nM
CNC(=O)N(O)CC1=Cc2cc(Oc3ccc(F)cc3)ccc2OC1 CHEMBL333219 IC50 45.0 nM
CN(O)C(=O)NCCCSc1nc2ccccc2s1 CHEMBL419745 EC50 45.0 nM
Cc1cc(/C=C/c2ccsc2)cc(C)c1O CHEMBL58979 IC50 45.0 nM
CCOC(=O)c1c(-c2cccc(Cl)c2)[nH]c2c1cc(O)c1ccccc12 CHEMBL519337 IC50 45.0 nM
CCOC(=O)c1c(Cc2ccc(Cl)c(Cl)c2)[nH]c2c1cc(O)c1ccccc12 CHEMBL4291851 IC50 45.0 nM
COc1ccc(Cc2oc3c(Cl)cc(C)c(O)c3c2C)cc1 CHEMBL18250 IC50 46.0 nM
CC1Cc2c(OCCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)Cc2nnn[nH]2)n3Cc2ccc(Cl)cc2)S1 CHEMBL92426 IC50 46.0 nM
O=C(O)/C=N/OCC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 CHEMBL349764 IC50 47.0 nM
C/C(=N\OC(c1ccc(OCc2nc3cc(F)ccc3s2)cc1Cl)C1CCCCC1)C(=O)O CHEMBL158767 IC50 48.0 nM
NC(=O)N(O)CCC#Cc1ccc(OCCN2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 CHEMBL187637 IC50 48.0 nM
CC(C)NC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 CHEMBL331062 IC50 49.0 nM
CCOC(=O)c1c(CCc2ccc(Cl)cc2)[nH]c2c1cc(O)c1ccccc12 CHEMBL520798 IC50 49.0 nM
O=C(c1ccc(OCc2ccccc2)cc1)N(O)CCc1ccccc1 CHEMBL293296 IC50 50.0 nM
C[C@@H](C#Cc1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O CHEMBL1907933 IC50 50.0 nM
O=C(c1cc(-c2ccoc2)c2ccc(OCc3cccc(C4(O)CCOCC4)c3)cc2c1)c1nccs1 CHEMBL127779 IC50 50.0 nM
OC1(c2cccc(COc3ccc4c(-c5ccoc5)cc(C5=NCCS5)cc4c3)c2)CCOCC1 CHEMBL128300 IC50 50.0 nM
CN(O)C(=O)/C=C/c1cccc(Oc2ccccc2)c1 CHEMBL146730 IC50 50.0 nM
Oc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL278041 IC50 50.0 nM
NS(=O)(=O)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL17210 IC50 50.0 nM
Nc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL17736 IC50 50.0 nM
O=[N+]([O-])c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL17331 IC50 50.0 nM
NCc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL17445 IC50 50.0 nM
CCC(OC)(c1cccc(OCc2ccc3c(-c4ccccc4)c4c(cc3c2)C(=O)OC4)c1)c1nccs1 CHEMBL151726 IC50 50.0 nM
COC1(c2cc(F)cc(OCc3ccc4c(c3)ncc(=O)n4C)c2)CCOCC1 CHEMBL89864 IC50 50.0 nM
C/C(=N\OC(Cc1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O CHEMBL159647 IC50 50.0 nM
C/C(=N\OCC#N)c1ccc(S(=O)(=O)c2cc([C@@]3(C)COC(C)(C)O3)cs2)cc1 CHEMBL129448 IC50 50.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCOC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL278027 IC50 50.0 nM
C[C@@H](C#Cc1ccc(Oc2ccc(F)cc2)o1)CN(O)C(N)=O CHEMBL1907812 IC50 50.0 nM
Cc1ccc2nc(-c3cccc(Oc4ccccc4)c3)c(NC3CCCCC3)n2c1 CHEMBL1958140 IC50 50.0 nM
Clc1ccc(-c2csc(Nc3ccc4c(c3)OCO4)n2)cc1 CHEMBL2023847 IC50 50.0 nM
Clc1ccc(-c2csc(Nc3ccc(N4CCOCC4)cc3)n2)cc1 CHEMBL3318382 IC50 50.0 nM
CCCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O CHEMBL3416360 IC50 50.0 nM
CC(C)=CCC/C(C)=C/Cc1c(O)cc2c(c1O)C(=O)C[C@@H](c1ccc(O)c(O)c1)O2 CHEMBL223256 IC50 50.0 nM
COc1cc(/C=C/c2ccc(O)c(O)c2)cc(OC)c1 CHEMBL332610 IC50 50.0 nM
C/C(=C\CC/C(C)=C/CC[C@]1(C)CCc2cc(O)cc(C)c2O1)CC/C=C(\C)C(=O)NCc1ccccc1 CHEMBL4743283 IC50 50.0 nM
C/C(=C\CC/C(C)=C/CC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1)CCC=C(CO)CO CHEMBL3092679 IC50 50.0 nM
Oc1ccc(-c2ccccc2)cc1O CHEMBL475398 IC50 50.0 nM
COc1ccc(COc2ccc3c4c2CC(C)Sc4c(CSc2ccccc2C(=O)O)n3Cc2ccc(Cl)cc2)nc1 CHEMBL415530 IC50 52.0 nM
CCCCC(O/N=C/C(=O)O)c1ccc(OCc2ccc3ccccc3n2)cc1 CHEMBL159909 IC50 52.0 nM
NC(=O)N(O)CC1COc2ccc(Oc3ccccc3)cc2C1 CHEMBL422430 IC50 53.0 nM
Cc1cc(/C=C/c2cccs2)cc(C)c1O CHEMBL56798 IC50 54.0 nM
CC1Cc2c(OCc3ccccn3)ccc3c2c(c(CSc2ccccc2C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL138551 IC50 55.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CSCCC(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL279871 IC50 55.0 nM
CCC(O)(c1cn(Cc2ccc3c(-c4ccccc4)c(C(N)=O)sc3c2)nn1)C(F)(F)F CHEMBL1289446 IC50 55.0 nM
O=C(O)/C=N/OC(c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1)C1CCCCC1 CHEMBL161303 IC50 56.0 nM
CC1=NN(CCOc2ccc3c(c2)Nc2ccccc2S3)C(=O)C1 CHEMBL158243 IC50 57.0 nM
NC(=O)N(O)CCC#Cc1ccc(OCCCCN2CCC(=C3c4ccc(Cl)cc4CCc4cccnc43)CC2)cc1 CHEMBL360202 IC50 57.0 nM
C/C(=C\CC/C(C)=C/CC[C@]1(C)CCc2cc(O)cc(C)c2O1)CC/C=C(\C)C(=O)O CHEMBL4463788 IC50 57.0 nM
CCCCCCc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(OC)c2c1=O CHEMBL69022 IC50 58.0 nM
CCCCC1Oc2c(C)c(C)c(O)c(C)c2S1 CHEMBL36043 IC50 59.0 nM
C/C(CCCC(=O)O)=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 CHEMBL163132 IC50 59.0 nM
CCn1c(=O)ccc2cc(COc3cc(F)cc(C4(OC)CCOCC4)c3)ccc21 CHEMBL459236 IC50 60.0 nM
CC[C@@]1(c2cc(F)cc(OCc3ccc4c(ccc(=O)n4C)c3)c2)CCO[C@H](C)C1 CHEMBL2092747 IC50 60.0 nM
NC(=O)N(O)CC#Cc1ccc(Oc2ccc(F)cc2)o1 CHEMBL264717 IC50 60.0 nM
COC1(c2cc(F)cc(OCc3ccc(-n4ccnc4C)cc3)c2)CCOCC1 CHEMBL163569 IC50 60.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCOc2ccccc2CC(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL437444 IC50 60.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCOc2ccccc2C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL341948 IC50 60.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCOc2ccccc2CC(=O)O)n3Cc2ccc(F)cc2)S1 CHEMBL342684 IC50 60.0 nM
CC(C)c1ccc2c(c1)c(SC(C)(C)C)c(CC(C)(C)C(=O)O)n2Cc1ccc(Cl)cc1 CHEMBL29097 IC50 60.0 nM
O=C(O)[C@@H](c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCC1 CHEMBL88712 IC50 60.0 nM
COC1(c2cc(Sc3ccc4c(c3)CCC(=O)N4C)cc(F)c2C)CCOCC1 CHEMBL129864 IC50 60.0 nM
C/C(=N\OC(c1ccc(OCc2nc3ccccc3s2)cc1)C1CCCCC1)C(=O)O CHEMBL349253 IC50 60.0 nM
CN1C(=O)CCc2ccc(Sc3ncc([C@@]4(C)COC(C)(C)O4)s3)cc21 CHEMBL339227 IC50 60.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2nc3ccccc3s2)cc1)C1CCCCC1 CHEMBL161414 IC50 60.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CCOC(C)c2nn[nH]n2)n3Cc2ccc(Cl)cc2)S1 CHEMBL16334 IC50 60.0 nM
NC(=O)N(O)CCO/N=C/c1ccc(Oc2ccc(F)cc2)o1 CHEMBL60523 IC50 60.0 nM
NC(=O)N(O)CC#Cc1cccc(Oc2ccccc2)c1 CHEMBL291993 IC50 60.0 nM
COc1cc(/C=C2\CCn3c2nc2ccccc2c3=O)cc(OC)c1OC(C)=O CHEMBL464446 IC50 60.0 nM
Clc1ccc2nc(-c3ccc(N4CCCCC4)cc3)c(NC3CCCCC3)n2c1 CHEMBL1957975 IC50 60.0 nM
CC(C)(C)OC(=O)N1CCN(c2ccc(-c3nc4ccc(Cl)cn4c3NC3CCCCC3)cc2)CC1 CHEMBL1957976 IC50 60.0 nM
O=C1N=C(c2ccc3ccccc3c2)S/C1=C\c1ccc(Oc2ccccc2)cc1 CHEMBL2029857 IC50 60.0 nM
CC(C)(C)c1cccc(NC2=NS(=O)(=O)c3cc([N+](=O)[O-])ccc32)c1 CHEMBL3288316 IC50 60.0 nM
Oc1ccc(Nc2nc(-c3ccc(F)cc3)cs2)cc1 CHEMBL3318368 IC50 60.0 nM
Cc1ccc(-c2csc(Nc3ccc(O)cc3)n2)cc1 CHEMBL1081479 IC50 60.0 nM
CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O CHEMBL221137 IC50 60.0 nM
CCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O CHEMBL3416358 IC50 60.0 nM
CC(C)Cc1ccc(C(C)c2nc3cc(CCC(=O)O)ccc3n2Cc2ccccc2Cl)cc1 CHEMBL4251024 IC50 60.0 nM
COc1cc([C@@H]2CC(=O)c3c(cc(O)c(C/C=C(\C)CCC=C(C)C)c3O)O2)cc(O)c1O CHEMBL463675 IC50 60.0 nM
COC1c2c(-c3ccccc3)c(-c3ccc(Cl)cc3)c(C)n2CC1(C)C CHEMBL5277274 IC50 60.0 nM
CN(O)C(=O)C1=Cc2cc(OCc3ccccc3)ccc2OC1 CHEMBL118212 IC50 61.0 nM
CC1=NN(CCOc2ccc3c(c2)Sc2ccccc2N3)C(=O)C1 CHEMBL155521 IC50 61.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(COCc2ccccc2C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL410493 IC50 62.0 nM
CCCCCCCCc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(OC)c2c1=O CHEMBL68593 IC50 62.0 nM
CCC1Oc2c(C)c(C)c(O)c(C)c2S1 CHEMBL285731 IC50 63.0 nM
CCCCNC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 CHEMBL331931 IC50 65.0 nM
COC(=O)c1ccc2c(c1)Nc1ccccc1O2 CHEMBL12681 IC50 65.0 nM
C=CCc1cc(/C=C/c2cccs2)cc(C)c1O CHEMBL56833 IC50 65.0 nM
CC[C@](O)(c1nnc(NCc2ccc3c(-c4ccc(F)cc4)cc(=O)oc3c2)o1)C(F)(F)F CHEMBL2105653 IC50 65.0 nM
O=C(O)c1noc(-c2ccc(OCc3ccc4ccccc4n3)cc2)c1-c1ccc(Cl)cc1 CHEMBL3781006 IC50 65.0 nM
Cc1cc(Nc2ncc(-c3ccc(F)cc3)o2)cc(C)c1O CHEMBL4172824 IC50 65.0 nM
CCN(Cc1ccccc1)C(=O)/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC[C@]1(C)CCc2cc(O)cc(C)c2O1 CHEMBL4757880 IC50 65.0 nM
CC1Cc2c(OCc3ccc(C#N)cn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL327889 IC50 66.0 nM
O=C(O)C1CCC(=NOC(c2ccc(OCc3ccc4ccccc4n3)cc2)C2CCCCC2)CC1 CHEMBL162778 IC50 67.0 nM
CCOC(=O)c1c(-c2ccc(Cl)cc2)[nH]c2c1cc(O)c1ccccc12 CHEMBL519150 IC50 67.0 nM
CCOC(=O)CNC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 CHEMBL119069 IC50 68.0 nM
NC(=O)N(O)CCC#Cc1ccc(OCCCCN2CCN([C@H](c3ccccc3)c3ccc(Cl)cc3)CC2)cc1 CHEMBL186125 IC50 68.0 nM
CC[C@](COC)(OC)c1cc(F)cc(OCc2ccc3c(ccc(=O)n3C)c2)c1 CHEMBL21651 IC50 70.0 nM
CCOC(=O)C1(c2cccc(OCc3ccc4c(ccc(=O)n4C)c3)c2)CCOCC1 CHEMBL20749 IC50 70.0 nM
NC(=O)N(O)CC#Cc1ccc(Cc2ccc(F)cc2)s1 CHEMBL359455 IC50 70.0 nM
O=C(c1ccccc1)c1cc(-c2ccoc2)c2ccc(OCc3cccc(C4(O)CCOCC4)c3)cc2c1 CHEMBL338461 IC50 70.0 nM
COC(=O)c1cc(-c2ccccc2)c2ccc(OCc3cccc(C4(O)CCOCC4)c3)cc2c1 CHEMBL414244 IC50 70.0 nM
OC1(c2cccc(COc3ccc4c(-c5ccoc5)cc(C5=NCCO5)cc4c3)c2)CCOCC1 CHEMBL129056 IC50 70.0 nM
CC1Cc2c(OCc3ccc4ccccc4n3)ccc3c2c(c(CSc2ccccc2C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL140157 IC50 70.0 nM
CC(C)N(O)C(=O)NCCCSc1nc2ccccc2s1 CHEMBL108854 EC50 70.0 nM
COc1ccc(-n2nc(CCC(=O)N(C)O)cc2-c2ccc(Cl)cc2)cc1 CHEMBL316040 EC50 70.0 nM
CN(O)C(=O)CSc1nc2ccccc2s1 CHEMBL108624 EC50 70.0 nM
CC(C)N(O)C(=O)NCCSc1nc2cc(Cl)ccc2s1 CHEMBL110863 EC50 70.0 nM
O=C1OCc2c1cc1cc3c(cc1c2-c1ccc2c(c1)OCO2)OCO3 CHEMBL304236 IC50 70.0 nM
COC1(c2cccc(OCC#Cc3ccccc3)c2)CCOCC1 CHEMBL315848 IC50 70.0 nM
CC(=O)N(C)c1ccc(Sc2ncc([C@@]3(C)COC(C)(C)O3)s2)cc1 CHEMBL128989 IC50 70.0 nM
C/C(=N\O[C@@H](c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O CHEMBL1788266 IC50 70.0 nM
CC(CC(=O)O)SCc1c2c3c(c(OCc4ccc(-c5ccccc5)cn4)ccc3n1Cc1ccc(Cl)cc1)CC(C)S2 CHEMBL16366 IC50 70.0 nM
N#Cc1cc(-c2ccoc2)c2ccc(OCc3cc(C4(O)CCOCC4)ccn3)cc2c1 CHEMBL99942 IC50 70.0 nM
CC(C#Cc1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O CHEMBL59598 IC50 70.0 nM
COc1ccc2cc(/C=C3\SC(c4ccc(Cl)cc4)=NC3=O)ccc2c1 CHEMBL2029849 IC50 70.0 nM
COc1cc(/C=C/C(=O)c2sc(NC(=O)c3ccccc3)nc2C)cc(OC)c1OC CHEMBL4464351 IC50 70.0 nM
COc1cc(/C=C/c2ccc(O)c(OC)c2)cc(OC)c1 CHEMBL119576 IC50 70.0 nM
C/C(=C\CC/C(C)=C/CC[C@]1(C)CCc2c(CN(C)C)c(O)cc(C)c2O1)CC/C=C(\C)C(=O)O CHEMBL4876438 IC50 70.0 nM
C=CCn1cc(Cc2c(O)n(-c3c(Cl)cccc3Cl)c3ccccc23)c2ccccc21 CHEMBL5431302 IC50 70.0 nM
Cc1c(C)c2c(c(C)c1O)SC(c1ccccc1)O2 CHEMBL290417 IC50 71.0 nM
O=C(Nc1ccc2c(c1)CCN2Cc1ccc(F)cc1)NC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3 CHEMBL5408127 IC50 71.0 nM
CSC1(c2cc(F)cc(OCc3ccc(-n4ccnc4C)cc3)c2)CCOCC1 CHEMBL349265 IC50 72.0 nM
CCOC(=O)N(O)CCC#Cc1ccc(OCCCCN2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 CHEMBL179590 IC50 72.0 nM
O=C(Nc1ccc2c(c1)CCN2Cc1ccc(F)cc1)C12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3 CHEMBL5415175 IC50 74.0 nM
COc1ccc(Cc2oc3c(Cl)cc(CCCO)c(O)c3c2C)cc1 CHEMBL18376 IC50 76.0 nM
COc1ccccc1CNC(=O)/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC[C@]1(C)CCc2cc(O)cc(C)c2O1 CHEMBL4746603 IC50 76.0 nM
Oc1ccc(-c2cccc3c2oc2ccccc23)cc1O CHEMBL5427414 IC50 76.0 nM
C/C(=C\CC/C(C)=C/CC[C@]1(C)CCc2cc(O)cc(C)c2O1)CC/C=C(\C)C(=O)NCc1cccnc1 CHEMBL4739891 IC50 77.0 nM
O=C(NCC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3)Nc1ccc2c(c1)CCN2Cc1ccc(F)cc1 CHEMBL5415470 IC50 78.0 nM
CC(/C=C/c1cccc(Oc2ccc(F)cc2)c1)N(O)C(N)=O CHEMBL86676 IC50 80.0 nM
C[C@H](C#Cc1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O CHEMBL90552 IC50 80.0 nM
CCOC1(c2cc(F)cc(OCc3ccc(-n4ccnc4C)cc3)c2)CCOCC1 CHEMBL423452 IC50 80.0 nM
Cn1nnc(-c2cc(-c3ccoc3)c3ccc(OCc4cccc(C5(O)CCOCC5)c4)cc3c2)n1 CHEMBL338132 IC50 80.0 nM
COc1cccc(-c2c3c(cc4cc(OCc5cccc(C6(O)CCOCC6)c5)ccc24)C(=O)OC3)c1 CHEMBL434057 IC50 80.0 nM
C[S+]([O-])c1ccc(-c2nc(-c3cccc(Cl)c3)c(-c3ccncc3)[nH]2)cc1 CHEMBL17389 IC50 80.0 nM
CN(C)Cc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL417087 IC50 80.0 nM
C[S+]([O-])c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 CHEMBL10 IC50 80.0 nM
COC1(c2cc(F)cc(OCc3ccc4c(c3)n(C)c(=O)n4C)c2)CCOCC1 CHEMBL315632 IC50 80.0 nM
COC1(c2cc(F)cc(OCc3ccc4c(c3)C(C)(C)C(=O)N4C)c2)CCOCC1 CHEMBL89526 IC50 80.0 nM
N#Cc1cc(-c2ccoc2)c2ccc(COc3cccc(C4(O)CC5COC(C4)O5)n3)cc2c1 CHEMBL95470 IC50 80.0 nM
CC1Cc2c(OCc3cc(-c4ccccc4)ccn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL319877 IC50 80.0 nM
C[C@H](C#Cc1ccc(Oc2ccc(F)cc2)o1)CN(O)C(N)=O CHEMBL1907824 IC50 80.0 nM
CN(C)c1ccc(-c2nc3ccc(Cl)cn3c2NC2CCCCC2)cc1 CHEMBL1957970 IC50 80.0 nM
Cc1ccc2nc(-c3ccc(Oc4ccccc4)cc3)c(NC3CCCCC3)n2c1 CHEMBL1958142 IC50 80.0 nM
COc1ccc(/C=C2\SC(c3ccc4ccccc4c3)=NC2=O)cc1 CHEMBL2029843 IC50 80.0 nM
COc1ccc(/C=C2\SC(c3ccc4ccccc4c3)=NC2=O)cc1O CHEMBL2029844 IC50 80.0 nM
CCCOc1ccc(/C=C2\SC(c3ccc(Cl)cc3)=NC2=O)cc1 CHEMBL2029845 IC50 80.0 nM
O=C1N=C(c2ccc(Cl)cc2)S/C1=C\c1ccc(Oc2ccccc2)cc1 CHEMBL2029847 IC50 80.0 nM
O=C1N=C(c2ccc(Cl)cc2)S/C1=C\c1ccc(OCc2ccccc2)cc1 CHEMBL2029848 IC50 80.0 nM
COc1ccc(/C=C2/SC(c3ccc(Cl)cc3)=NC2=O)cc1 CHEMBL3353727 IC50 80.0 nM
COc1ccc(/C=C2/SC(c3cccc4ccccc34)=NC2=O)cc1 CHEMBL3353728 IC50 80.0 nM
COc1ccc(C(=O)Nc2nc(C)c(C(=O)/C=C/c3ccc(C)cc3)s2)cc1 CHEMBL4568352 IC50 80.0 nM
Cc1cc(OCc2nc3ccccc3s2)ccc1NC(=O)Nc1cc(Cl)cc(Cl)c1 CHEMBL4464435 IC50 80.0 nM
COc1cccc(CNC(=O)/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC[C@]2(C)CCc3c(C)c(O)cc(C)c3O2)c1 CHEMBL4779142 IC50 80.0 nM
Cc1c(C)c2c(c(C)c1O)CC[C@@](C)(CCCC(C)CCCC(C)CCCC(C)C(=O)O)O2 CHEMBL2151600 IC50 80.0 nM
CCOC(=O)c1c(Cc2ccc(Cl)cc2)[nH]c2c1cc(O)c1ccccc12 CHEMBL490656 IC50 84.0 nM
CN(O)C(=O)/C=C/c1ccc2c(c1)Nc1ccccc1O2 CHEMBL12361 IC50 85.0 nM
NC(=O)N(O)C[C@H]1COc2ccc(Oc3ccc(F)cc3)cc2O1 CHEMBL162497 IC50 85.0 nM
CC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 CHEMBL118914 IC50 86.0 nM
CCCCCCCCCCc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(OC)c2c1=O CHEMBL66340 IC50 86.0 nM
CCCc1cc(/C=C/c2cccs2)cc(OC)c1O CHEMBL434783 IC50 86.0 nM
COc1cc(/C=C/c2cccs2)cc(C)c1O CHEMBL413324 IC50 86.0 nM
CCOC(=O)c1c(Cc2cccc(Cl)c2)[nH]c2c1cc(O)c1ccccc12 CHEMBL490461 IC50 86.0 nM
CC1Oc2ccc(Oc3ccccc3)cc2C=C1CN(O)C(N)=O CHEMBL332092 IC50 87.0 nM
CN(O)C(=O)c1ccc2c(c1)Nc1ccccc1O2 CHEMBL12362 IC50 87.0 nM
O=C(O)/C=N/OC(c1ccc(OCc2nc3cc(F)ccc3s2)cc1)C1CCCCC1 CHEMBL158108 IC50 87.0 nM
O=C1OCc2c1cc1cc(OCc3ccc4ccccc4n3)ccc1c2-c1ccccc1 CHEMBL65345 IC50 88.0 nM
CCCCCCOc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(OC)c2c1=O CHEMBL304280 IC50 88.0 nM
CC1(C)Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL96635 IC50 88.0 nM
CCC(O)(c1cn(Cc2ccc3c(-c4ccccc4)c(C(C)O)sc3c2)nn1)C(F)(F)F CHEMBL1289214 IC50 88.0 nM
NC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OCC1 CHEMBL357336 IC50 89.0 nM
NC(=O)N(O)CCC#Cc1ccc(OCCCCN2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 CHEMBL444083 IC50 89.0 nM
Cc1c(C)c2c(c(C)c1O)SC(CCCO)O2 CHEMBL38172 IC50 90.0 nM
CN(O)C(=O)NCCSc1nc2ccccc2s1 CHEMBL320329 EC50 90.0 nM
C/C(=N\OC(c1ccc(OCc2ccc3ccccc3n2)cc1SC1CCCCC1)C1CCCCC1)C(=O)O CHEMBL157536 IC50 90.0 nM
C/C(=N\O)c1ccc(S(=O)(=O)c2cc([C@@]3(C)COC(C)(C)O3)cs2)cc1 CHEMBL129666 IC50 90.0 nM
CCc1cc(/C=C/c2cccs2)cc(OC)c1O CHEMBL293825 IC50 90.0 nM
CC(/C(F)=C/c1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O CHEMBL294028 IC50 90.0 nM
COC(=O)N(O)CCC#Cc1ccc(OCCCCN2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 CHEMBL366925 IC50 90.0 nM
NC(=O)N(O)CCC#Cc1ccc(OCCCN2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 CHEMBL185825 IC50 90.0 nM
COc1ccc(/C=C2\SC(c3ccc(Cl)cc3)=NC2=O)cc1 CHEMBL1765899 IC50 90.0 nM
COc1ccc(C2=NC(=O)/C(=C/c3ccc(Cl)cc3)S2)cc1 CHEMBL2029832 IC50 90.0 nM
COc1ccc(/C=C2\SC(c3ccc(Br)cc3)=NC2=O)cc1 CHEMBL2029834 IC50 90.0 nM
O=C1N=C(c2ccc(Cl)cc2)S/C1=C\c1cccc(Oc2ccccc2)c1 CHEMBL2029846 IC50 90.0 nM
O=C1N=C(c2ccc(Oc3ccccc3)cc2)S/C1=C\c1ccc(Oc2ccccc2)cc1 CHEMBL2029855 IC50 90.0 nM
O=C(Nc1ccc(OCc2nc3ccccc3s2)cc1)Nc1cc(Cl)cc(Cl)c1 CHEMBL4456287 IC50 90.0 nM
C[C@H](C#Cc1ccc(Cc2ccc(F)cc2)s1)N(O)C(N)=O CHEMBL59356 IC50 90.0 nM
C/C(=C\CC/C(C)=C/CC[C@]1(C)CCc2c(C)c(O)cc(C)c2O1)CCC=C(CO)CO CHEMBL4865488 IC50 90.0 nM
C/C(=C\CC/C(C)=C/CC[C@]1(C)CCc2cc(OC(=O)CCC(=O)O)cc(C)c2O1)CCC=C(CO)CO CHEMBL4856987 IC50 90.0 nM
COc1ccc(C2OCC(=CCC/C(C)=C/CC/C(C)=C/CC[C@]3(C)CCc4c(C)c(O)c(CO)c(C)c4O3)CO2)cc1OC CHEMBL4849927 IC50 90.0 nM
NC(=O)N(O)CC1=Cc2cc(Oc3ccc(F)cc3)ccc2OCC1 CHEMBL355979 IC50 91.0 nM
O=C(O)/C=N/OC(c1ccc(/C=C/c2ccc3ccccc3n2)cc1)C1CCCCC1 CHEMBL159726 IC50 91.0 nM
COc1ccc(/C=C/c2cc(C)c(O)c(C)c2)cc1 CHEMBL54221 IC50 91.0 nM
CCOC(=O)c1c(Cc2c(F)cccc2F)[nH]c2c1cc(O)c1ccccc12 CHEMBL4286295 IC50 94.0 nM
COc1ccc(CNC(=O)/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC[C@]2(C)CCc3cc(O)cc(C)c3O2)cc1 CHEMBL4743535 IC50 94.0 nM
CCCCn1c(CC(C)(C)C(=O)O)c2c3c(c(OCc4ccc(-c5ccccc5)cn4)ccc31)CC(C)S2 CHEMBL317085 IC50 95.0 nM
CCOC(=O)c1c(Cc2ccc(Br)cc2)[nH]c2c1cc(O)c1ccccc12 CHEMBL484482 IC50 95.0 nM
Cc1ccc(S(=O)(=O)n2cc(C(=O)C(=O)N[C@H](CCC(=O)O)C(=O)O)c3ccccc32)cc1 CHEMBL3113620 Ki 95.0 nM
NC(=O)N(O)CCC#Cc1ccc(OCCCN2CCN([C@H](c3ccccc3)c3ccc(Cl)cc3)CC2)cc1 CHEMBL187264 IC50 96.0 nM
CCOC(=O)c1c(Cc2ccc(F)cc2)[nH]c2c1cc(O)c1ccccc12 CHEMBL484277 IC50 96.0 nM
C[C@H](C#Cc1cccc(C(=O)NCCC(c2ccccc2)c2ccc(Cl)c(Cl)c2)c1)N(O)C(N)=O CHEMBL4745687 IC50 96.0 nM
CC1Cc2c(OCc3ccc(-c4ccccc4)cn3)ccc3c2c(c(C(=O)O)n3Cc2ccc(Cl)cc2)S1 CHEMBL330189 IC50 97.0 nM
CCOC(=O)c1c(Cc2ccccc2Cl)[nH]c2c1cc(O)c1ccccc12 CHEMBL523292 IC50 97.0 nM
COc1ccc(CNC(=O)/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC[C@]2(C)CCc3c(C)c(O)cc(C)c3O2)cc1 CHEMBL4745718 IC50 97.0 nM
CNC(=O)N(O)CC1COc2ccc(Oc3ccccc3)cc2O1 CHEMBL165067 IC50 98.0 nM
COc1ccc(Cc2oc3c(Cl)cc(C(C)(C)C)c(O)c3c2C)cc1 CHEMBL278507 IC50 99.0 nM