Cc1nnc2c(NC3CCN(CC(C)(C)F)CC3)cc(C(=O)N3[C@@H]4c5ccccc5C[C@H]3C(=O)N[C@@H]4C(C)C)nn12 CHEMBL5079885 pKd 1.259 nM
CO[C@H]1CNC[C@@H](OCC2CCC(F)(F)CC2)[C@@H]1Nc1ncc(-c2cncc(C)c2)c2cc(C)c(=O)[nH]c12 CHEMBL4206758 Kd 1.3 nM
Cc1cncc(-c2ccc(N[C@@H]3CCNC[C@H]3OCC3CCS(=O)(=O)CC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL3590405 pKd 7.943 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)N[C@@](C)(C4CC4)C3=O)ccc2Br)C1 CHEMBL4449894 pKd 10.0 nM
Cc1nnc2c(NCCCN3CCCC3)cc(C(=O)N3[C@@H]4c5ccccc5C[C@H]3C(=O)N[C@@H]4C(C)C)nn12 CHEMBL5087319 IC50 14.0 nM
Cc1cncc(-c2cnc(N[C@@H]3CCN(C)C[C@H]3OCC3CCS(=O)(=O)CC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL3590408 pKi 19.95 nM
Cc1nnc2c(NCCCN3CCC(F)(F)CC3)cc(C(=O)N3[C@@H]4c5ccccc5C[C@H]3C(=O)N[C@@H]4C(C)C)nn12 CHEMBL5093862 pIC50 19.95 nM
Cc1nnc2c(NC3CCN(CC(C)(F)F)CC3)cc(C(=O)N3[C@@H]4c5ccccc5C[C@H]3C(=O)N[C@@H]4C(C)C)nn12 CHEMBL5090369 pIC50 19.95 nM
CNC(=O)[C@@H](Cc1ccc([N+](=O)[O-])cc1)NC(=O)c1cc(-c2ccc(CN[C@H](C)c3ccc(C)cc3)o2)ccc1Cl CHEMBL5397368 IC50 22.0 nM
COc1cc(Cl)c(C(=O)N[C@@H](CN[C@H]2CC[C@@H](N)CC2)Cc2ccc(C#N)cc2)cc1-c1ccc(CN[C@H](C)c2ccc(C)cc2)o1 CHEMBL4536031 IC50 22.0 nM
C[C@@H]1CN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)NC(C)(C4CC4)C3=O)ccc2Br)C[C@H]1C CHEMBL4576280 pIC50 25.12 nM
CN1CCN(c2nc(C(=O)c3ccccc3)c3cnn(C)c3n2)CC1 CHEMBL4529901 IC50 30.0 nM
Cc1cncc(-c2cnc(N[C@@H]3CCNC[C@H]3OCC3CCS(=O)(=O)CC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL3590383 pIC50 31.62 nM
Cc1nnc2c(NC3CCN(C)CC3)cc(C(=O)N3[C@H]4Cc5ccccc5[C@@H]3CNC4=O)nn12 CHEMBL5077167 pIC50 31.62 nM
Cc1cc2c(-c3cncc(N)c3)cnc(N[C@@H]3CCNC[C@H]3OCC3CCCCC3)c2[nH]c1=O CHEMBL3590391 pIC50 39.81 nM
Cc1cncc(-c2ccc(N[C@@H]3CCNC[C@H]3OCC3CCC(F)(F)CC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL4244134 pIC50 39.81 nM
Cc1nnc2c(NCCCN3CCCC3)cc(C(=O)N3[C@H]4Cc5ccccc5[C@@H]3CNC4=O)nn12 CHEMBL5086059 pIC50 39.81 nM
CCc1cc2c(-c3cncc(C)c3)cnc(N[C@@H]3CCNC[C@H]3OCC3CCS(=O)(=O)CC3)c2[nH]c1=O CHEMBL3590407 pIC50 50.12 nM
Cc1cncc(-c2cnc(N[C@@H]3CCNC[C@H]3OC[C@H]3C[C@@H](C)S(=O)(=O)[C@@H](C)C3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL3590406 pIC50 63.1 nM
C[C@H]1NC(=O)[C@@H]2Cc3ccccc3[C@H]1N2C(=O)c1cn(C)c(=O)c2[nH]c3ccc(OC(F)(F)F)cc3c12 CHEMBL5086260 IC50 78.0 nM
Cc1cc2c(-c3cccnc3)cnc(N[C@@H]3CCNC[C@H]3OCC3CCS(=O)(=O)CC3)c2[nH]c1=O CHEMBL3590381 pIC50 100.0 nM
COc1cncc(-c2cnc(N[C@@H]3CCNC[C@H]3OCC3CCS(=O)(=O)CC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL3590385 pIC50 100.0 nM
Cc1cncc(-c2cnc(N[C@@H]3C[C@H]4CC[C@H](N4)[C@H]3CCC3CCC(F)(F)CC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL4242484 pIC50 100.0 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)N[C@](C)(C4CC4)C3=O)ccc2Br)C1 CHEMBL4589592 pIC50 100.0 nM
CO[C@H]1CNC[C@@H](OCC2CCS(=O)(=O)CC2)[C@@H]1Nc1ncc(-c2cncc(C)c2)c2cc(C)c(=O)[nH]c12 CHEMBL4250812 pIC50 125.89 nM
Cc1cncc(-c2cnc(N[C@@H]3CCNC[C@H]3OCC3CCCCC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL3590389 pKd 158.49 nM
Cc1cc2c(-c3cccnc3)cnc(N[C@@H]3CCNC[C@H]3OCC3CCOCC3)c2[nH]c1=O CHEMBL3590380 pIC50 199.53 nM
CO[C@H]1CNC[C@@H](OCC2CCOCC2)[C@@H]1Nc1ncc(-c2cncc(C)c2)c2cc(C)c(=O)[nH]c12 CHEMBL4246358 pIC50 199.53 nM
C[C@H]1NC(=O)[C@@H]2Cc3ccccc3[C@H]1N2C(=O)c1cn(C)c(=O)c2[nH]c3ccccc3c12 CHEMBL5074983 pIC50 199.53 nM
COc1cncc(-c2cnc(N[C@@H]3CCNC[C@H]3OCC3CCOCC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL3590384 pIC50 251.19 nM
Cc1cncc(-c2cnc(N[C@@H]3CCNC[C@H]3OCC3CCOCC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL3590382 pIC50 251.19 nM
Cc1cncc(-c2cnc(N[C@@H]3C[C@H]4CC[C@H](N4)[C@H]3CCC3CCOCC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL4241003 pIC50 251.19 nM
Cc1cncc(-c2cnc(N[C@@H]3C[C@H]4CC[C@H](N4)[C@H]3CCC3CCS(=O)(=O)CC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL4246286 pIC50 251.19 nM
Cc1cncc(-c2ccc(N[C@@H]3C[C@H]4CC[C@H](N4)[C@H]3CCC3CCS(=O)(=O)CC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL4246741 pIC50 251.19 nM
C[C@@H]1CN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)CNC3=O)ccc2Cl)C[C@H]1C CHEMBL4464650 pIC50 251.19 nM
C[C@@]1(C2CC2)NC(=O)N(CC(=O)Nc2ccc(Br)c(S(=O)(=O)N3CCCC3)c2)C1=O CHEMBL4565203 pIC50 251.19 nM
Cc1nnc2c(N)cc(C(=O)N3[C@H]4Cc5ccccc5[C@@H]3CNC4=O)nn12 CHEMBL5084768 pIC50 251.19 nM
CC1(C2CC2)NC(=O)N(CC(=O)Nc2ccc(Br)c(S(=O)(=O)N3CCCCC3)c2)C1=O CHEMBL4583297 pIC50 316.23 nM
Cc1nnc2c(NC3CCN(C)CC3)cc(C(=O)N3[C@H]4Cc5ccccc5[C@@H]3CNC4=O)cn12 CHEMBL5092181 IC50 370.0 nM
Cn1cc(C(=O)N2[C@H]3Cc4ccccc4[C@@H]2CNC3=O)c2c([nH]c3ccccc32)c1=O CHEMBL5083025 pIC50 398.11 nM
CC(C)[C@H]1NC(=O)[C@@H]2Cc3ccccc3[C@H]1N2C(=O)c1cn(C)c(=O)c2[nH]c3ccccc3c12 CHEMBL5093167 pIC50 398.11 nM
Cc1cc2ccnc(N[C@@H]3CCNC[C@H]3OCC3CCS(=O)(=O)CC3)c2[nH]c1=O CHEMBL3590396 pIC50 501.19 nM
O=C(CN1C(=O)CNC1=O)Nc1ccc(Cl)c(S(=O)(=O)N2CCC(C3CC3)C2)c1 CHEMBL4521850 pIC50 501.19 nM
CC1CCCN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)CNC3=O)ccc2Br)C1 CHEMBL4522533 pIC50 630.96 nM
CCC1CCN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)CNC3=O)ccc2Cl)C1 CHEMBL4463848 pIC50 630.96 nM
Cc1cc2c(-c3cncc(CO)c3)cnc(NC3CCN(CCCN)CC3)c2[nH]c1=O CHEMBL4860188 pIC50 630.96 nM
Cc1cc2c(-c3cncc(N)c3)cnc(NC3CCNCC3)c2[nH]c1=O CHEMBL3585459 pIC50 794.33 nM
Cc1cc2c(-c3cncnc3)cnc(N[C@@H]3CCNC[C@H]3OCC3CCOCC3)c2[nH]c1=O CHEMBL3590386 pIC50 794.33 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)CNC3=O)ccc2Cl)C1 CHEMBL4457036 pIC50 794.33 nM
CN(C)CC1CCN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)CNC3=O)ccc2Cl)C1 CHEMBL4445372 pIC50 1000.0 nM
C[C@@H]1CCN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)CNC3=O)ccc2Cl)C1 CHEMBL4555757 pIC50 1000.0 nM
O=C(CN1C(=O)CNC1=O)Nc1ccc(Cl)c(S(=O)(=O)N2CCC3(CC3)C2)c1 CHEMBL4464057 pIC50 1000.0 nM
COCC1CCN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)CNC3=O)ccc2Cl)C1 CHEMBL4464309 pIC50 1000.0 nM
CC1(C2CC2)NC(=O)N(CC(=O)Nc2ccc(Cl)c(S(=O)(=O)N3CCCC3)c2)C1=O CHEMBL4587991 pIC50 1000.0 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)Cc3noc4ccccc34)ccc2Br)C1 CHEMBL4470476 pIC50 1000.0 nM
COCc1cnnn1CC(=O)Nc1ccc(Br)c(S(=O)(=O)N2CC[C@H](C)C2)c1 CHEMBL4454840 pIC50 1000.0 nM
Cc1cncc(-c2cnc(NC3CCN(CCCN)CC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL4878541 pIC50 1000.0 nM