CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCOCC2)c(=O)n4C)cn1 CHEMBL3960662 IC50 0.04 nM
CC(C)n1c(=O)n(C)c2cnc3cc(F)c(-c4ccc(OCCCN5CCCCC5)nc4)cc3c21 CHEMBL4594429 IC50 0.09 nM
O=c1cc(N2CCOCC2)nc(N2CCCCC[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4850755 Ki 0.1 nM
CO[C@H]1CC[C@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(OCCCN(C)C)nc5)cc4c32)C1 CHEMBL3923182 IC50 0.152 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(OCCCN6CCCC6)nc5)cc4c32)C1 CHEMBL3936943 IC50 0.17 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(OCCCN6CCCCC6)nc5)cc4c32)C1 CHEMBL3960323 IC50 0.2 nM
O=c1cc(N2CCOCC2)nc(N2C[C@H]3C[C@H]3[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4858310 Ki 0.2 nM
COc1cc2ncc3c(c2cc1-c1cn(C)nc1C)n(-c1c(F)cncc1OC)c(=O)n3C CHEMBL5314413 IC50 0.2 nM
CO[C@@H]1CC[C@@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(OCCCN(C)C)nc5F)cc4c32)C1 CHEMBL4115047 IC50 0.208 nM
CO[C@H]1CC[C@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(NCCCN6CCCCC6)nc5)cc4c32)C1 CHEMBL3952396 IC50 0.22 nM
Cn1c(=O)n([C@@H]2CCCOC2)c2c3cc(-c4ccc(OCCCN5CCCC5)nc4)ccc3ncc21 CHEMBL4110135 IC50 0.233 nM
Cn1c(=O)n([C@H]2CCCOC2)c2c3cc(-c4ccc(OCCCN5CCCC5)nc4)ccc3ncc21 CHEMBL3947316 IC50 0.238 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n([C@H]2C[C@@H](O)C2)c(=O)n4C)cn1 CHEMBL3889770 IC50 0.24 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(OCCCN(C)C)nc5)cc4c32)C1 CHEMBL3936734 IC50 0.249 nM
CNCCCOc1ccc(-c2ccc3ncc4c(c3c2)n([C@H]2C[C@@H](OC)C2)c(=O)n4C)cn1 CHEMBL3954517 IC50 0.249 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(OCCCN6CCC6)nc5)cc4c32)C1 CHEMBL3979811 IC50 0.29 nM
C[C@H](Nc1c(C(N)=O)nnc2ccc(-c3ccc(OCCCN(C)C)nc3)cc12)C1CCOCC1 CHEMBL4217549 IC50 0.29 nM
O=c1cc(N2CCOCC2)cc(N2C[C@@H]3C[C@@H]3[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4862803 Ki 0.3 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCOCC2)c(=O)n4C)c(F)n1 CHEMBL3927821 IC50 0.301 nM
Cn1c(=O)n(C2CCC2)c2c3cc(-c4ccc(OCCCN5CCCC5)nc4)ccc3ncc21 CHEMBL3890876 IC50 0.31 nM
CO[C@H]1CC[C@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(OCCCN(C)C)nc5)cc4c32)C1 CHEMBL3929864 IC50 0.31 nM
CO[C@@H]1CC[C@@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(OCCCN(C)C)nc5)cc4c32)C1 CHEMBL4112870 IC50 0.315 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)NCCN5CC(F)C5)cc4)cc3c21 CHEMBL5191923 IC50 0.32 nM
CO[C@H]1CC[C@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(OCCCN(C)C)nc5F)cc4c32)C1 CHEMBL3898641 IC50 0.324 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n([C@H]2CCCOC2)c(=O)n4C)cn1 CHEMBL3890490 IC50 0.329 nM
CO[C@H]1CC[C@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(OCCCN6CCCC6)nc5)cc4c32)C1 CHEMBL3904625 IC50 0.334 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n([C@H]2CCCOC2)c(=O)n4C)c(F)n1 CHEMBL3935033 IC50 0.365 nM
C[C@@H]1CCN(c2nc(N3CCOCC3)cc(=O)[nH]2)[C@H]1Cc1ccccc1 CHEMBL4852400 Ki 0.4 nM
CN(C)CCCOc1ccc(-c2ccc3ncn(-c4ccc5c(c4)N(S(=O)(=O)C4CC4)CC5)c3n2)cn1 CHEMBL5408388 IC50 0.41 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(OCCCN6CCCC6)nc5)cc4c32)C1 CHEMBL3895211 IC50 0.418 nM
Cn1c(=O)n(C2CCC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)ccc3ncc21 CHEMBL3970378 IC50 0.434 nM
Cn1c(=O)n([C@H]2C[C@@H](O)C2)c2c3cc(-c4ccc(OCCCN5CCCC5)nc4)ccc3ncc21 CHEMBL3898165 IC50 0.447 nM
CN(C)CCCOc1ccc(-c2ccc3ncn(-c4ccc5c(c4)N(S(C)(=O)=O)CC5)c3n2)cn1 CHEMBL5429597 IC50 0.48 nM
Cn1c(=O)n([C@H]2CCOC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)ccc3ncc21 CHEMBL3964241 IC50 0.493 nM
Cc1cn(C)nc1[C@H](C)Nc1c(C(N)=O)nnc2ccc(-c3ccc(OCCCN4CCCC4)nc3)cc12 CHEMBL4210045 IC50 0.5 nM
CC1(CNc2ccc3c(c2)Cc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)COC1 CHEMBL4763842 IC50 0.5 nM
O=c1cc(-c2cccc3c2Sc2ccc(O)cc2C3)oc(N2CCOCC2)c1 CHEMBL4792191 IC50 0.5 nM
O=c1cc(-c2cccc3c2Sc2ccc(OCCN4C[C@H]5C[C@@H]4CO5)cc2C3)oc(N2CCOCC2)c1 CHEMBL4763108 IC50 0.5 nM
O=c1cc(-c2cccc3c2Sc2ccc(OCCN4CCC(F)(F)C4)cc2C3)oc(N2CCOCC2)c1 CHEMBL4748079 IC50 0.5 nM
C[C@@H]1CN(CCOc2ccc3c(c2)Cc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)C[C@H](C)O1 CHEMBL4788241 IC50 0.5 nM
O=c1cc(-c2cccc3c2Sc2ccc(OCC4CCOCC4)cc2C3)oc(N2CCOCC2)c1 CHEMBL4781601 IC50 0.5 nM
COc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4792737 Ki 0.5 nM
CO[C@@H]1CC[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(OCCCN(C)C)nc5)cc4c32)C1 CHEMBL4114446 IC50 0.507 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n([C@@H]2CCCOC2)c(=O)n4C)c(F)n1 CHEMBL4109764 IC50 0.552 nM
Cn1c(=O)n([C@H]2CCCOC2)c2c3cc(-c4ccc(OCCCN5CCCC5)nc4F)ccc3ncc21 CHEMBL3906409 IC50 0.554 nM
CNCCCOc1ccc(-c2ccc3ncc4c(c3c2)n([C@H]2CCCOC2)c(=O)n4C)cn1 CHEMBL3890358 IC50 0.555 nM
CS(=O)(=O)N1CCc2ccc(-n3cnc4ccc(-c5ccc(OCCCN6CCCC6)nc5)nc43)cc21 CHEMBL5404153 IC50 0.56 nM
Cn1c(=O)n([C@H]2CCCOC2)c2c3cc(-c4ccc(OCCCN5CCCC5)nc4)c(F)cc3ncc21 CHEMBL3890119 IC50 0.563 nM
CNCCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCOCC2)c(=O)n4C)cn1 CHEMBL3984782 IC50 0.567 nM
CO[C@H]1C[C@@H](n2c(=O)[nH]c3cnc4ccc(-c5ccc(OCCCN6CCCC6)nc5)cc4c32)C1 CHEMBL3955034 IC50 0.589 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc5c(c4)N(S(C)(=O)=O)CCC5)c3n2)cc1 CHEMBL5399607 IC50 0.59 nM
CNCCCOc1ccc(-c2ccc3ncc4c(c3c2)n([C@@H]2CCCOC2)c(=O)n4C)cn1 CHEMBL4114155 IC50 0.592 nM
COCc1ccc(-c2cc3c(N[C@@H](C)c4ccn(C)n4)c(C(N)=O)cnc3cc2F)cn1 CHEMBL4166405 IC50 0.6 nM
O=C(Nc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2)C1CC1 CHEMBL4794627 IC50 0.6 nM
CC(=O)Nc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4790714 IC50 0.6 nM
O=c1cc(-c2cccc3c2Sc2ccc(OCCN4CC(F)C4)cc2C3)oc(N2CCOCC2)c1 CHEMBL4786685 IC50 0.6 nM
C[C@H](CN1CCOCC1)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4745255 IC50 0.6 nM
C[C@H](O)COc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4763102 IC50 0.6 nM
O=c1cc(N2CCOCC2)nc(N2C[C@@H]3C[C@@H]3[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4857803 Ki 0.6 nM
CN(C)CCCOc1ccc(-c2ccc3ncn(-c4ccc5c(c4)N(S(C)(=O)=O)CCC5)c3n2)cn1 CHEMBL5433386 IC50 0.6 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4F)cc3c21 CHEMBL5183158 IC50 0.65 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc5c(c4)N(S(C)(=O)=O)CC5)c3c2)cc1 CHEMBL5436153 IC50 0.68 nM
Cn1c(=O)n([C@@H]2CCCOC2)c2c3cc(-c4ccc(OCCCN5CCCC5)nc4)c(F)cc3ncc21 CHEMBL4114060 IC50 0.69 nM
CNC(=O)c1nnc2ccc(-c3ccc(OCCCN(C)C)nc3)cc2c1N[C@@H](C)C1CCOCC1 CHEMBL4218854 IC50 0.7 nM
O=c1cc(-c2cccc3c2Sc2ccc(OCCN4CCC(F)(F)CC4)cc2C3)oc(N2CCOCC2)c1 CHEMBL4783324 IC50 0.7 nM
CN1CCN(CCOc2ccc3c(c2)Cc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)CC1 CHEMBL4777914 IC50 0.7 nM
C[C@@H](COc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2)N1CCOCC1 CHEMBL4784220 IC50 0.7 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)c(F)c4)cc3c21 CHEMBL5181829 IC50 0.71 nM
Cn1c(=O)n([C@@H]2CCOC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)ccc3ncc21 CHEMBL4110616 IC50 0.715 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCC2)c(=O)n4C)c(F)n1 CHEMBL3974856 IC50 0.722 nM
CO[C@@H]1CC[C@@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(NCCCN6CCCCC6)nc5)cc4c32)C1 CHEMBL4115552 IC50 0.741 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4ccc(-c5ccc(OCCCN(C)C)nc5F)cc4c32)C1 CHEMBL3958682 IC50 0.76 nM
CS(=O)(=O)N1CCc2ccc(-n3cnc4ccc(-c5ccc(OCCCN6CCCCC6)nc5)nc43)cc21 CHEMBL5438530 IC50 0.76 nM
Cn1c(=O)n([C@@H]2CCCOC2)c2c3cc(-c4ccc(OCCCN5CCC5)nc4)ccc3ncc21 CHEMBL4109786 IC50 0.765 nM
CCS(=O)(=O)N1CCc2ccc(-n3cnc4ccc(-c5ccc(OCCCN(C)C)nc5)nc43)cc21 CHEMBL5399096 IC50 0.77 nM
CN(C)CCCOc1ccc(-c2cc3c(cc2F)ncc2c3n(C3CCOCC3)c(=O)n2C)cn1 CHEMBL3986918 IC50 0.78 nM
Cn1c(=O)n([C@H]2CCCOC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)c(F)cc3ncc21 CHEMBL3972724 IC50 0.799 nM
O=c1cc(-c2cccc3c2Sc2ccccc2C3)oc(N2CCOCC2)c1 CHEMBL4569967 IC50 0.8 nM
CCCCNC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN(C)C)nc3)cc2n1 CHEMBL5438394 IC50 0.8 nM
CS(=O)(=O)N1CCCc2ccc(-n3cnc4ccc(-c5ccc(OCCCN6CCCC6)nc5)nc43)cc21 CHEMBL5417382 IC50 0.85 nM
Cc1cn(C)nc1[C@H](C)Nc1c(C(N)=O)nnc2ccc(-c3ccc(OCCCN(C)C)nc3)cc12 CHEMBL4212961 IC50 0.9 nM
C[C@@H]1CN(c2cc(=O)[nH]c(N3C[C@@H]4C[C@@H]4[C@@H]3Cc3ccccc3)n2)CCO1 CHEMBL4853948 Ki 0.9 nM
CN(C)CCCOc1ccc(-c2ccc3ncc(N(C)C(=O)NC4CCCCC4)nc3c2)cn1 CHEMBL5411336 IC50 0.9 nM
CN(C)CCCOc1ccc(-c2ccc3ncc(N(C)C(=O)Nc4ccccc4Cl)nc3c2)cn1 CHEMBL5434323 IC50 0.9 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)NCCN5CCC5)cc4)cc3c21 CHEMBL5170132 IC50 0.92 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n([C@@H]2CCCOC2)c(=O)n4C)cn1 CHEMBL4111966 IC50 0.935 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2(C)CCOCC2)c(=O)n4C)cn1 CHEMBL3961688 IC50 0.96 nM
CS(=O)(=O)N1CCCc2ccc(-n3cnc4ccc(-c5ccc(OCCCN6CCCCC6)nc5)nc43)cc21 CHEMBL5437608 IC50 0.96 nM
CNCCCOc1ccc(-c2ccc3ncn(-c4ccc5c(c4)N(S(C)(=O)=O)CC5)c3n2)cn1 CHEMBL5422787 IC50 0.98 nM
CN(C)CCCOc1ccc(-c2cc3c(cc2F)ncc2c3n([C@@H]3CCCOC3)c(=O)n2C)cn1 CHEMBL4110596 IC50 1.0 nM
C[C@@H](CN1C[C@H]2C[C@@H]1CO2)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4797110 IC50 1.0 nM
C[C@@H](CN1CCOCC12COC2)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4751373 IC50 1.0 nM
C[C@@H](CN1CCOCC1)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4742203 IC50 1.0 nM
C[C@H](COc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2)N1CCOCC1 CHEMBL4797559 IC50 1.0 nM
C[C@@H]1CN([C@H](C)COc2ccc3c(c2)Cc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)C[C@H](C)O1 CHEMBL4761765 IC50 1.0 nM
COC[C@@H](C)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4752634 IC50 1.0 nM
O=c1cc(-c2cccc3c2Sc2ccc(OC4COC4)cc2C3)oc(N2CCOCC2)c1 CHEMBL4760480 IC50 1.0 nM
O=c1cc(N2CCOCC2)cc(N2CCCCC[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4872830 Ki 1.0 nM
Oc1cc(N2CCOCC2)nc(N2CCC[C@@H]2Cc2ccccc2)n1 CHEMBL4878312 Ki 1.0 nM
C[C@@H]1CN(c2cc(N3CCCCC[C@@H]3Cc3ccccc3)[nH]c(=O)c2)CCO1 CHEMBL4845919 Ki 1.0 nM
C[C@@H]1CN(c2cc(=O)[nH]c(N3CCCCC[C@@H]3Cc3ccccc3)n2)CCO1 CHEMBL4852763 Ki 1.0 nM
CCc1ncc(S(=O)(=O)Nc2cc(-c3ccc4ncc5c(c4c3)C3(CCC3)C(=O)N5C)cnc2OCCCN(C)C)s1 CHEMBL5175568 IC50 1.0 nM
CN(C)CCCOc1ncc(-c2ccc3ncc4c(c3c2)C2(CCC2)C(=O)N4C)cc1NS(=O)(=O)C(F)(F)F CHEMBL5205796 IC50 1.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(OCCCN(C)C)nc4)cc3c21 CHEMBL5435260 IC50 1.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5cccs5)cc4)c3c2)cc1 CHEMBL5437024 IC50 1.0 nM
CC(=O)Nc1cccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc32)c1 CHEMBL5433726 IC50 1.0 nM
CN(C)CCCOc1ccc(-c2ccc3ncc(N(C)C(=O)NC4CCCC4)nc3c2)cn1 CHEMBL5402194 IC50 1.0 nM
CCN(CC)CCCOc1ccc(-c2ccc3ncc(N(C)C(=O)NC(C)C)nc3c2)cn1 CHEMBL5423087 IC50 1.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN4CCCCC4)nc3F)cc2n1 CHEMBL5438262 IC50 1.0 nM
CN(C)CCCOc1ccc(-c2cc3c(cc2F)ncc2c3n([C@H]3CCCOC3)c(=O)n2C)c(F)n1 CHEMBL3891448 IC50 1.02 nM
CO[C@H]1C[C@@H](n2c(=O)[nH]c3cnc4ccc(-c5ccc(OCCCN(C)C)nc5)cc4c32)C1 CHEMBL3898563 IC50 1.03 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(OCCCN(C)C)nc5)cc4c32)C1 CHEMBL3950905 IC50 1.05 nM
Cn1c(=O)n([C@H]2C[C@@H](O)C2)c2c3cc(-c4ccc(OCCCN5CCC5)nc4)ccc3ncc21 CHEMBL3984179 IC50 1.05 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n([C@@H]2CCOC2)c(=O)n4C)cn1 CHEMBL4110389 IC50 1.07 nM
Cn1c(=O)n([C@H]2CCCOC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)ccc3ncc21 CHEMBL3932205 IC50 1.09 nM
Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)c(F)cc3ncc21 CHEMBL3946515 IC50 1.1 nM
C[C@H](Nc1c(C(N)=O)nnc2ccc(-c3ccc(OCCCN4CCCC4)nc3)cc12)c1ccn(C)n1 CHEMBL4208569 IC50 1.1 nM
Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4ccc(OCCCN5CCCC5)nc4)ccc3ncc21 CHEMBL3963290 IC50 1.12 nM
CN(C)CCCOc1ccc(-c2cc3c(cc2F)ncc2c3n([C@H]3CCCOC3)c(=O)n2C)cn1 CHEMBL3912673 IC50 1.14 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN4CCCCC4)nc3)cc2n1 CHEMBL5419324 IC50 1.15 nM
Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)ccc3ncc21 CHEMBL3946340 IC50 1.2 nM
CN(C)C1CN(CC(=O)Nc2ccc(-c3ccc4ncn(-c5ccc6c(c5)N(S(C)(=O)=O)CC6)c4c3)cc2)C1 CHEMBL5432184 IC50 1.2 nM
Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4ccc(OCCCN5CCC5)nc4)ccc3ncc21 CHEMBL3912416 IC50 1.33 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N(C)CCN(C)C)cc4)cc3c21 CHEMBL5191914 IC50 1.33 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n([C@H]2CCOC2)c(=O)n4C)c(F)n1 CHEMBL3955067 IC50 1.34 nM
O=c1cc(-c2cccc3c2Sc2ccc(OCCN4CCCC45CCOC5)cc2C3)oc(N2CCOCC2)c1 CHEMBL4756577 IC50 1.4 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n([C@@H]2CCOC2)c(=O)n4C)c(F)n1 CHEMBL4108353 IC50 1.44 nM
CO[C@@H]1CC[C@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(OCCCN(C)C)nc5)cc4c32)C1 CHEMBL3923162 IC50 1.45 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2COC2)c(=O)n4C)cn1 CHEMBL3924247 IC50 1.46 nM
CNCCCOc1ccc(-c2ccc3ncn(-c4ccc5c(c4)N(S(C)(=O)=O)CCC5)c3n2)cn1 CHEMBL5414690 IC50 1.5 nM
CC(C)n1c(=O)n(C)c2cnc3ccc(-c4ccc(OCCCN5CCCC5)nc4)cc3c21 CHEMBL5171429 IC50 1.59 nM
CS(=O)(=O)Nc1cccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN5CC(F)C5)cc4)cc32)c1 CHEMBL5408220 IC50 1.6 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3n2)n(C2CCOCC2)c(=O)n4C)cn1 CHEMBL4163629 IC50 1.7 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc3c21 CHEMBL5171246 IC50 1.7 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN4CCCC4)nc3)cc2n1 CHEMBL5425392 IC50 1.75 nM
Cn1c(=O)n([C@@H]2CCCOC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)ccc3ncc21 CHEMBL4112039 IC50 1.78 nM
C[C@H](Nc1c(C(N)=O)nnc2ccc(-c3ccc(OCCCN4CCCC4)nc3)cc12)C1CCOCC1 CHEMBL4213503 IC50 1.8 nM
C[C@@H](Nc1c(C(N)=O)cnc2ccc(-c3cccnc3)cc12)c1ccc(Cl)cc1 CHEMBL4565988 IC50 2.0 nM
C[C@@H]1CN(C[C@H](C)Oc2ccc3c(c2)Cc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)C[C@H](C)O1 CHEMBL4754219 IC50 2.0 nM
C[C@H](CN1C[C@@H](C)O[C@@H](C)C1)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4794132 IC50 2.0 nM
C[C@@H](CN1CCOC2(CC2)C1)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4759581 IC50 2.0 nM
O=c1cc(N2CCOCC2)cc(N2C[C@H]3C[C@H]3[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4874640 Ki 2.0 nM
C[C@@H]1CN(c2cc(=O)[nH]c(N3C[C@H]4C[C@H]4[C@@H]3Cc3ccccc3)n2)CCO1 CHEMBL4867495 Ki 2.0 nM
CN1CCN(C(=O)Nc2ccc(-c3ccc4ncc5c(c4c3)n(C3CCOCC3)c(=O)n5C)cn2)CC1 CHEMBL5201821 IC50 2.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5CCC(NC(=O)OC(C)(C)C)CC5)cc4)cc3c21 CHEMBL5195854 IC50 2.0 nM
C[C@@H]1CN(CC(=O)Nc2ccc3c(c2)Cc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)C[C@H](C)O1 CHEMBL2140173 Ki 2.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(N)nc4)cc3c21 CHEMBL5438059 IC50 2.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(OCCCN5CCCCC5)nc4)cc3c21 CHEMBL5400360 IC50 2.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(OCCCN5CCCC5)nc4)cc3c21 CHEMBL5414607 IC50 2.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(OCCCN5CCN(C)CC5)nc4)cc3c21 CHEMBL5430425 IC50 2.0 nM
CCCS(=O)(=O)Nc1cccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc32)c1 CHEMBL5438075 IC50 2.0 nM
C=CCNC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN(C)C)nc3)cc2n1 CHEMBL5407799 IC50 2.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN(C)C)nc3)cc2n1 CHEMBL5415162 IC50 2.0 nM
CC1CCC(NC(=O)N(C)c2cnc3ccc(-c4ccc(OCCCN(C)C)nc4)cc3n2)CC1 CHEMBL5414867 IC50 2.0 nM
CN(C)CCCOc1ccc(-c2cc3c(cc2F)ncc2c3n(C3(C)CCOCC3)c(=O)n2C)cn1 CHEMBL3951966 IC50 2.03 nM
COc1ccc(-c2ccc(-n3cnc4ccc(-c5ccc(NC(=O)NCCN(C)C)cc5)nc43)cc2)cc1 CHEMBL5429786 IC50 2.1 nM
CN1CCC(NC(=O)Nc2ccc(-c3ccc4ncn(-c5cccc(NS(C)(=O)=O)c5)c4c3)cc2)C1 CHEMBL5409888 IC50 2.1 nM
O=c1cc(-c2cccc3c2Sc2ccccc2S3)oc(N2CCOCC2)c1 CHEMBL222102 Ki 2.2 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5ccccc5)cc4)c3n2)cc1 CHEMBL5413347 IC50 2.2 nM
COc1cc(OC)cc(-c2ccc(-n3cnc4ccc(-c5ccc(NC(=O)NCCN(C)C)cc5)cc43)cc2)c1 CHEMBL5433108 IC50 2.3 nM
CO[C@H]1CC[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(OCCCN(C)C)nc5)cc4c32)C1 CHEMBL4110808 IC50 2.43 nM
CN1CCCC(NC(=O)Nc2ccc(-c3ccc4ncn(-c5cccc(NS(C)(=O)=O)c5)c4c3)cc2)C1 CHEMBL5415802 IC50 2.5 nM
CN(C)CCCOc1ccc(-c2ccc3ncn(-c4ccc5c(c4)N(S(C)(=O)=O)CC5)c3c2)cn1 CHEMBL5404392 IC50 2.5 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(OCCCN(C)C)nc5F)cc4c32)C1 CHEMBL3898577 IC50 2.6 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4cccc(NS(C)(=O)=O)c4)c3c2)c(F)c1 CHEMBL5399076 IC50 2.6 nM
CN1CCN(CCC(=O)Nc2ccc3c(c2)Sc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)CC1 CHEMBL4159350 IC50 3.0 nM
CC(C)(O)C1CCN(CCOc2ccc3c(c2)Cc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)CC1 CHEMBL4791332 IC50 3.0 nM
CN1CC[C@@H](Oc2ccc3c(c2)Cc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)C1 CHEMBL4788818 IC50 3.0 nM
O=c1cc(N2CCOCC2)cc(N2CC[C@@H](F)[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4866506 Ki 3.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)c(F)c4F)cc3c21 CHEMBL5179580 IC50 3.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(Br)cc4)c3c2)cc1 CHEMBL5404077 IC50 3.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5ccco5)cc4)c3c2)cc1 CHEMBL5403116 IC50 3.0 nM
CCCNC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN(C)C)nc3)cc2n1 CHEMBL5439932 IC50 3.0 nM
COc1ccc(NC(=O)N(C)c2cnc3ccc(-c4ccc(OCCCN(C)C)nc4)cc3n2)cc1 CHEMBL5412929 IC50 3.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN4CCOCC4)nc3)cc2n1 CHEMBL5419474 IC50 3.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN4CCN(C)CC4)nc3)cc2n1 CHEMBL5429982 IC50 3.0 nM
O=c1[nH]c2cnc3ccc(-c4ccc(OCCCN5CCCCC5)nc4)cc3c2n1C1CCOCC1 CHEMBL3972478 IC50 3.01 nM
Cn1c(=O)n(C2COC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)ccc3ncc21 CHEMBL3899194 IC50 3.02 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCC2)c(=O)n4C)cn1 CHEMBL3943165 IC50 3.15 nM
O=c1cc(-c2cccc3c2Sc2ccc(OC4CCOCC4)cc2C3)oc(N2CCOCC2)c1 CHEMBL4747809 IC50 3.2 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4[nH]c(=O)n(C5CCOCC5)c4c3c2)cn1 CHEMBL3907190 IC50 3.22 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4cccc(NS(C)(=O)=O)c4)c3c2)cc1F CHEMBL5414060 IC50 3.3 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)NCCN5CC(F)(F)C5)cc4)cc3c21 CHEMBL5198342 IC50 3.31 nM
CC(CN(C)C)NC(=O)Nc1ccc(-c2ccc3ncn(-c4cccc(NS(C)(=O)=O)c4)c3c2)cc1 CHEMBL5408860 IC50 3.6 nM
CN(C)CCCOc1ccc(-c2cc3c(cc2F)ncc2c3n(C3COC3)c(=O)n2C)cn1 CHEMBL3957991 IC50 3.8 nM
C[C@H](Nc1c(C(N)=O)nnc2ccc(-c3ccc(OCCCN(C)C)nc3)cc12)c1ccn(C)n1 CHEMBL4217902 IC50 3.9 nM
CNC(=O)c1nnc2ccc(-c3ccc(OCCCN(C)C)nc3)cc2c1N[C@@H](C)c1nn(C)cc1C CHEMBL4213919 IC50 3.9 nM
CN(C)CCOC(=O)Nc1ccc(-c2ccc3ncn(-c4cccc(NS(C)(=O)=O)c4)c3c2)cc1 CHEMBL5427491 IC50 3.9 nM
CC(C)n1c(=O)n(C)c2cnc3ccc(-c4ccc(OCCCN(C)C)nc4)cc3c21 CHEMBL5182423 IC50 3.98 nM
O=c1cc(-c2cccc3c2Sc2ccc(OC4CN(CC(F)F)C4)cc2C3)oc(N2CCOCC2)c1 CHEMBL4788662 IC50 4.0 nM
CO[C@@H](C)COc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4760622 IC50 4.0 nM
COc1ccc2c(c1)Cc1cccc(-c3cc(N4CCOCC4)cc(=O)[nH]3)c1S2 CHEMBL4879094 Ki 4.0 nM
C[C@@H]1CN(c2cc(N3C[C@@H]4C[C@@H]4[C@@H]3Cc3ccccc3)[nH]c(=O)c2)CCO1 CHEMBL4856420 Ki 4.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)NC5CCN(C)CC5)cc4)cc3c21 CHEMBL5172175 IC50 4.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5CC(N(C)C)C5)cc4)cc3c21 CHEMBL5209089 IC50 4.0 nM
C[C@H](c1ccc(F)cc1)n1nnc2cnc3ccc(-c4ccc(N)nc4)cc3c21 CHEMBL5431045 IC50 4.0 nM
C[C@H](c1cccc(F)c1)n1nnc2cnc3ccc(-c4ccc(N)nc4)cc3c21 CHEMBL5394989 IC50 4.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(C5=CCCCC5)cc4)c3c2)cc1 CHEMBL5404241 IC50 4.0 nM
COCc1ccc(-c2ccc3ncc(C(N)=O)c(N[C@@H](C)C4CCOCC4)c3c2)cn1 CHEMBL4218734 IC50 4.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN4CCCC4)nc3F)cc2n1 CHEMBL5406188 IC50 4.0 nM
COc1cc(-c2ccc(-n3cnc4ccc(-c5ccc(NC(=O)NCCN(C)C)cc5)cc43)cc2)cc(OC)c1OC CHEMBL5427404 IC50 4.4 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2COC2)c(=O)n4C)c(F)n1 CHEMBL3932835 IC50 4.76 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5cccc([N+](=O)[O-])c5)cc4)c3c2)cc1 CHEMBL5400086 IC50 4.8 nM
Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4ccc(OCCC[N+](C)(C)[O-])nc4)ccc3ncc21 CHEMBL4162142 IC50 5.0 nM
COC[C@H]1c2cc(OC)ccc2Sc2c(-c3cc(=O)cc(N4CCOCC4)o3)cccc21 CHEMBL4783046 IC50 5.0 nM
COc1cccc([C@@H](C)n2nnc3cnc4ccc(-c5ccc(N)nc5)cc4c32)c1 CHEMBL5437498 IC50 5.0 nM
CS(=O)(=O)N1CCc2ccc(-n3cnc4ccc(-c5ccc(OCCCN)nc5)nc43)cc21 CHEMBL5426792 IC50 5.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3cnc(OCCCN4CCCCC4)cc3F)cc2n1 CHEMBL5412263 IC50 5.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4cccc(N(C)S(C)(=O)=O)c4)c3c2)cc1 CHEMBL5431231 IC50 5.5 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(NCCN(C)C)nc5)cc4c32)C1 CHEMBL4175071 IC50 6.0 nM
O=c1cc(N2CCOCC2)cc(N2CCC[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4873212 Ki 6.0 nM
O=c1cc(N2CCOCC2)cc(N2CCC(F)(F)[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4858974 Ki 6.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(N5CCN(C)CC5)nc4)cc3c21 CHEMBL5427702 IC50 6.0 nM
CCNC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN(C)C)nc3)cc2n1 CHEMBL5400114 IC50 6.0 nM
C[C@@H]1CN(CC(=O)Nc2ccc3c(c2)Sc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)C[C@H](C)O1 CHEMBL3765783 IC50 6.3 nM
C[C@@H]1CC(NC(=O)Cc2ccc3c(c2)Sc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)C[C@H](C)O1 CHEMBL4780892 IC50 6.3 nM
Cn1c(=O)n(-c2ccc(C(C)(C)C#N)cc2)c2c3cc(-c4cnc5ccccc5c4)ccc3ncc21 CHEMBL1879463 IC50 7.0 nM
CCN1CC(Oc2ccc3c(c2)Cc2cccc(-c4cc(=O)cc(N5CCOCC5)o4)c2S3)C1 CHEMBL4740512 IC50 7.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5CCC(N(C)C)C5)cc4)cc3c21 CHEMBL5171104 IC50 7.0 nM
COc1cccc(-c2ccc(-n3cnc4ccc(-c5ccc(NC(=O)NCCN(C)C)cc5)cc43)cc2)c1 CHEMBL5407685 IC50 7.1 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(C#N)cc12 CHEMBL4593348 IC50 8.0 nM
O=c1cc(N2CCOCC2)cc(N2CCCC[C@@H]2Cc2ccccc2)[nH]1 CHEMBL4846084 Ki 8.0 nM
Nc1ccc(-c2ccc3ncc4nnn(Cc5ccccc5)c4c3c2)cn1 CHEMBL5440480 IC50 8.0 nM
Cc1nc2ccc(-c3ccc(NC(=O)NCCN(C)C)cc3)cc2n1-c1cccc(NS(=O)(=O)C2CC2)c1 CHEMBL5429485 IC50 8.0 nM
CN(C)CCCOc1ccc(-c2ccc3ncc(N(C)C(=O)NC4CC4)nc3c2)cn1 CHEMBL5416391 IC50 8.0 nM
CN(C)CCCOc1ccc(-c2ccc3ncc(N(C)C(=O)N[C@]45C[C@@H]6C[C@@H](C[C@H](C6)C4)C5)nc3c2)cn1 CHEMBL5437395 IC50 8.0 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(NC(=O)CCCN(C)C)nc5)cc4c32)C1 CHEMBL4161022 IC50 8.2 nM
CCC(CC)CNc1c(C(N)=O)cnc2cc(F)c(-c3cnc(NCCN4CCCC4)nc3)cc12 CHEMBL4167277 IC50 8.6 nM
CC[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(N)nc4)cc3c21 CHEMBL5409310 IC50 9.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4cccnc4)cc3c21 CHEMBL5437044 IC50 9.0 nM
Cc1nc(OCCCN2CCCCC2)ccc1-c1ccc2ncc(N(C)C(=O)NC(C)C)nc2c1 CHEMBL5398961 IC50 9.0 nM
COc1ccc(-c2ccc(-n3cnc4ccc(-c5ccc(NC(=O)NCCN(C)C)cc5)cc43)cc2)cc1 CHEMBL5399889 IC50 9.3 nM
Cc1nc2ccc(-c3ccc(NC(=O)NCCN(C)C)cc3)cc2n1-c1cccc(NS(C)(=O)=O)c1 CHEMBL5423270 IC50 9.5 nM
CN(C)CCCOc1ccc(-c2ccc3ncn(-c4ccc(-c5ccccc5)cc4)c3c2)cn1 CHEMBL5428230 IC50 9.9 nM
COCc1ccc(-c2cc3c(N[C@@H](C)c4nn(C)cc4C)c(C(N)=O)cnc3cc2F)cn1 CHEMBL4215266 IC50 10.0 nM
O=C(CN1CCCC1)Nc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4792283 IC50 10.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(OCCCCN(C)C)nc4)cc3c21 CHEMBL5410373 IC50 10.0 nM
COc1ccc(-c2ccc(-n3cnc4ccc(-c5ccc(OCCCN(C)C)nc5)nc43)cc2)cc1 CHEMBL5409771 IC50 10.0 nM
CS(=O)(=O)Nc1cccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN5CC(F)(F)C5)cc4)cc32)c1 CHEMBL5399614 IC50 10.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCC4CCCN4C)nc3)cc2n1 CHEMBL5418386 IC50 10.0 nM
C[C@@H]1CN(c2cc(N3C[C@H]4C[C@H]4[C@@H]3Cc3ccccc3)[nH]c(=O)c2)CCO1 CHEMBL4869283 Ki 11.0 nM
CN(C)CCCOc1ccc(-c2ccc3ncn(-c4ccc(-c5ccccc5)cc4)c3n2)cn1 CHEMBL5407215 IC50 11.0 nM
COC(=O)N1CCC(n2c(=O)n(C)c3cnc4ccc(-c5ccc(OC)nc5)cc4c32)CC1 CHEMBL3967825 IC50 11.2 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(NS(=O)(=O)C5CC5)cc4)c3c2)cc1 CHEMBL5409366 IC50 12.0 nM
COc1cc2ncnc(-n3nc(-c4ccccn4)nc3N)c2cc1OC CHEMBL2143829 IC50 12.9 nM
CC(=O)Nc1ccc(-c2ccc3ncc4nnn([C@H](C)c5ccccc5)c4c3c2)cn1 CHEMBL5416200 IC50 13.0 nM
COc1ccc(-c2ccc3ncc4nnn([C@H](C)c5ccccc5)c4c3c2)cn1 CHEMBL5436168 IC50 13.0 nM
CN(C)CCCOc1ccc(-c2ccc3ncc(N(C)C(=O)NC(C)(C)C)nc3c2)cn1 CHEMBL5440952 IC50 13.0 nM
CC(=O)c1cccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc32)c1 CHEMBL5417889 IC50 14.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5ccc(F)cc5)cc4)c3c2)cc1 CHEMBL5435162 IC50 14.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(N)cc4)cc3c21 CHEMBL5394320 IC50 15.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4cnc(N)nc4)cc3c21 CHEMBL5440253 IC50 15.0 nM
CC(=O)N(C)c1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4744385 IC50 16.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5CCC(N)CC5)cc4)cc3c21 CHEMBL5175636 IC50 16.0 nM
CCS(=O)(=O)Nc1cccc(-n2c(C)nc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc32)c1 CHEMBL5417183 IC50 16.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCN4CCCCC4)nc3C#N)cc2n1 CHEMBL5439397 IC50 16.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5ccccc5F)cc4)c3c2)cc1 CHEMBL5399805 IC50 17.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5cccc(F)c5)cc4)c3c2)cc1 CHEMBL5401947 IC50 17.0 nM
CC(=O)Nc1ccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc32)cc1 CHEMBL5426509 IC50 18.0 nM
COCc1ccc(-c2cc3c(N[C@@H](C)c4nn(C)cc4F)c(C(N)=O)cnc3cc2F)cn1 CHEMBL4517663 IC50 19.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(OCCN(C)C)nc4)cc3c21 CHEMBL5422063 IC50 19.0 nM
C[C@@H]1COCCN1c1nc(N2CCOC[C@@H]2C)nc2sc(-c3cc[nH]n3)nc12 CHEMBL4518369 IC50 20.0 nM
O=c1cc(-c2cccc3c2Sc2ccc(O[C@@H]4CCN(CC(F)F)C4)cc2C3)oc(N2CCOCC2)c1 CHEMBL4783168 IC50 20.0 nM
CC(C)n1nnc2cnc3ccc(-c4ccc(N)nc4)cc3c21 CHEMBL5398563 IC50 20.0 nM
CN(C)CCN(C)CC(=O)Nc1ccc(-c2ccc3ncn(-c4cccc(NS(C)(=O)=O)c4)c3c2)cc1 CHEMBL5426020 IC50 20.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5ccc(F)c(F)c5)cc4)c3c2)cc1 CHEMBL5406686 IC50 21.0 nM
CN(C)CCCOc1ccc(-c2ccc3nnc4c(c3c2)n(C2CCOCC2)c(=O)n4C)cn1 CHEMBL4172819 IC50 22.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccnc(N)c4)cc3c21 CHEMBL5440917 IC50 22.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(NS(C)(=O)=O)cc4)c3c2)cc1 CHEMBL5396564 IC50 22.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCC4CCCN(C)C4)nc3)cc2n1 CHEMBL5409082 IC50 22.0 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(OCCN(C)C)nc5)cc4c32)C1 CHEMBL4173181 IC50 23.0 nM
CO[C@@H]1CCN(c2cc(N3CCOCC3)cc(=O)[nH]2)[C@H]1Cc1ccccc1 CHEMBL4849786 Ki 23.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(N5C[C@@H]6C[C@H]5CO6)cc4)c3c2)cc1 CHEMBL5423767 IC50 23.0 nM
CN1CCC(COc2ccc(-c3ccc4ncn(-c5ccc6c(c5)N(S(C)(=O)=O)CC6)c4c3)cn2)C1 CHEMBL5412666 IC50 23.0 nM
COc1ccc2c(c1)Cc1cccc(-c3cc(O)nc(N4CCOCC4)n3)c1S2 CHEMBL4874992 Ki 25.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5C[C@@H]6C[C@H]5CN6C)cc4)cc3c21 CHEMBL5195925 IC50 25.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(O)nc4)cc3c21 CHEMBL5439440 IC50 25.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5ccc(F)cc5F)cc4)c3c2)cc1 CHEMBL5440521 IC50 25.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5cc(F)cc(F)c5)cc4)c3c2)cc1 CHEMBL5428074 IC50 25.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCCCN(C)C)nc3)cc2n1 CHEMBL5413082 IC50 26.0 nM
COc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCN(C(C)=O)CC2)c(=O)n4C)cn1 CHEMBL3946658 IC50 26.5 nM
Nc1ccc(-c2ccc3ncc4ccc(=O)n(-c5cccc(C(F)(F)F)c5)c4c3c2)cn1 CHEMBL1765602 EC50 28.0 nM
C[C@@H](CN1CCCC12COC2)Oc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4787824 IC50 30.0 nM
O=c1cc(N2CCOCC2)cc(N2CCCC2Cc2ccccc2)[nH]1 CHEMBL4873551 Ki 30.0 nM
CC(C)C(=O)Nc1ccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc32)cc1 CHEMBL5430514 IC50 30.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCCN(C)C)nc3)cc2n1 CHEMBL5427955 IC50 30.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(Cl)nc4)cc3c21 CHEMBL5423955 IC50 31.0 nM
COc1cccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc32)c1 CHEMBL5426571 IC50 31.0 nM
CC(C)NC(=O)N(C)c1cnc2ccc(-c3ccc(OCC4CCN(C)C4)nc3)cc2n1 CHEMBL5425985 IC50 31.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)c(F)c4Cl)cc3c21 CHEMBL5181690 IC50 32.0 nM
CS(=O)(=O)N1CCc2ccc(-n3cnc4ccc(-c5ccc(OCCCO)nc5)nc43)cc21 CHEMBL5409195 IC50 32.0 nM
C[C@H](Nc1c(C(N)=O)nnc2ccc(-c3ccc(OCCN(C)C)nc3)cc12)c1ccn(C)n1 CHEMBL4205148 IC50 35.0 nM
Cc1ccc(-c2ccc3ncc4nnn([C@H](C)c5ccccc5)c4c3c2)cn1 CHEMBL5408985 IC50 35.0 nM
COc1ccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc32)cc1 CHEMBL5430334 IC50 35.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)c(C)c4F)cc3c21 CHEMBL5189299 IC50 37.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3ccc(CS(C)(=O)=O)nc3)cc12 CHEMBL4576302 IC50 39.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(N)cc4)c3c2)cc1 CHEMBL5430515 IC50 42.0 nM
COCc1ccc(-c2ccc3nnc(C(N)=O)c(N[C@@H](C)c4nn(C)cc4C)c3c2)cn1 CHEMBL4216325 IC50 44.0 nM
CNCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)on2)cc1 CHEMBL3989870 Ki 44.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3ccc(COC)nc3)cc12 CHEMBL4560522 IC50 45.0 nM
C[C@@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(N)nc4)cc3c21 CHEMBL4554781 IC50 45.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(N5CCOCC5)cc4)c3c2)cc1 CHEMBL5402737 IC50 45.0 nM
CCNCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)on2)cc1 CHEMBL4533440 Ki 47.0 nM
CN(C)CCCOc1ccc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)cn1 CHEMBL4876439 IC50 47.0 nM
CNC(=O)c1nnc2ccc(-c3ccc(OCCN(C)C)nc3)cc2c1N[C@@H](C)C1CCOCC1 CHEMBL4205675 IC50 49.0 nM
C[C@@H](Nc1c(C(N)=O)cnc2ccc(C#N)cc12)c1ccc(Cl)cc1 CHEMBL4527822 IC50 49.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3ccc(C)nc3)cc12 CHEMBL4567042 IC50 50.0 nM
COc1ccc2c(c1)C1(CCOCC1)c1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4783459 IC50 50.0 nM
COCc1ccc(-c2cc3c(N[C@@H](C)C4CCOCC4)c(C(N)=O)cnc3cc2F)cn1 CHEMBL4533539 IC50 52.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(O)cc4)cc3c21 CHEMBL5433892 IC50 52.0 nM
C[C@@H](c1cccc(F)c1)n1nnc2cnc3ccc(-c4ccc(N)nc4)cc3c21 CHEMBL5401984 IC50 53.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(F)nc4)cc3c21 CHEMBL5428887 IC50 57.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(Cl)cc4)c3n2)cc1 CHEMBL5416917 IC50 58.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccccc4)c3c2)cc1 CHEMBL5439520 IC50 60.0 nM
C[C@H](Nc1c(C(N)=O)nnc2ccc(-c3ccc(NCCN(C)C)nc3)cc12)C1CCOCC1 CHEMBL4217379 IC50 61.0 nM
N#CCN1CCC(n2c(=O)cnc3cnc4ccc(-c5ccc(N)nc5)cc4c32)CC1 CHEMBL4079746 IC50 62.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4cccc(NC(=O)OC(C)(C)C)c4)c3c2)cc1 CHEMBL5422552 IC50 62.0 nM
COCc1ccc(-c2ccc3ncc(C(N)=O)c(N[C@@H](C)c4ccn(C)n4)c3c2)c(F)n1 CHEMBL4548927 IC50 63.0 nM
COc1ccccc1-c1ccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc32)cc1 CHEMBL5395167 IC50 64.0 nM
CN(C)CCCOc1ccc(-c2ccc3ncn(-c4ccccc4)c3c2)cn1 CHEMBL5410182 IC50 66.0 nM
CN1CCC(COc2ccc(-c3ccc4ncn(-c5ccc(-c6ccccc6)cc5)c4c3)cn2)C1 CHEMBL5411299 IC50 66.0 nM
CCC(C)C(=O)Nc1ccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc32)cc1 CHEMBL5436492 IC50 67.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3ccc(CS(C)(=O)=O)cc3)cc12 CHEMBL4519670 IC50 70.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(N5CCCC5)nc4)cc3c21 CHEMBL5440344 IC50 71.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4cccc(N)c4)c3c2)cc1 CHEMBL5424349 IC50 71.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3cccnc3)cc12 CHEMBL4543897 IC50 73.0 nM
COCc1ccc(-c2cc3c(N[C@@H](C)c4ccn(C)n4)c(C(N)=O)cnc3cc2F)c(F)n1 CHEMBL4563993 IC50 73.0 nM
COc1ncc(-c2ccc3ncc4c(c3c2)n(C2CC2)c(=O)n4C)cc1NS(=O)(=O)C1CC1 CHEMBL3970131 IC50 74.1 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(F)cc4)c3c2)cc1 CHEMBL5412153 IC50 75.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5CCN(C)CC5)cc4)cc3c21 CHEMBL5193567 IC50 78.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccccc4F)c3c2)cc1 CHEMBL5416815 IC50 78.0 nM
CC[C@@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(N)nc4)cc3c21 CHEMBL5409323 IC50 79.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccc([C@H](C)N)cc4)no3)n2)cc1 CHEMBL4467848 Ki 82.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3ccc(CO)nc3)cc12 CHEMBL4588822 IC50 87.0 nM
Oc1cc(N2CCC[C@@H]2Cc2ccccc2)nc(N2CCOCC2)n1 CHEMBL4852165 Ki 87.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(C5CCCCC5)cc4)c3c2)cc1 CHEMBL5406261 IC50 89.0 nM
CNCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)on2)c(Cl)c1 CHEMBL4448538 Ki 93.0 nM
COCc1ccc(-c2cc3c(cc2F)ncc2c3n([C@H]3C[C@@H](OC)C3)c(=O)n2C)cn1 CHEMBL4160664 IC50 100.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5CCN(C)CC5)cc4F)cc3c21 CHEMBL5200163 IC50 101.0 nM
COc1ccc([C@H](C)n2nnc3cnc4ccc(-c5ccc(N)nc5)cc4c32)cc1 CHEMBL5433610 IC50 103.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccc([C@@H](C)N)cc4)no3)n2)cc1 CHEMBL4566104 Ki 105.0 nM
COc1ccc2c(c1)Cc1cccc(-c3cc(=O)cc(N4CCOCC4)[nH]3)c1S2 CHEMBL4872482 Ki 110.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(N5CCCCC5)cc4)c3c2)cc1 CHEMBL5397766 IC50 110.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccc(CN)cc4)no3)n2)cc1 CHEMBL4443525 Ki 115.0 nM
CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc4ccccc4[nH]3)n2)cc1 CHEMBL1766804 IC50 120.0 nM
C[C@H](Nc1c(C(N)=O)cnc2ccc(-c3cccnc3)cc12)c1ccn(C)n1 CHEMBL4591401 IC50 124.0 nM
COc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCNCC2)c(=O)n4C)cn1 CHEMBL3938266 IC50 125.0 nM
C[C@@H]1Cn2ncc(-c3ccc(S(C)(=O)=O)cc3)c2CN1c1ccnc2[nH]ccc12 CHEMBL3355072 IC50 130.0 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(C(=O)NCCN(C)C)nc5)cc4c32)C1 CHEMBL4171626 IC50 130.0 nM
NC(=O)c1cnc2ccc(-c3cccnc3)cc2c1NC1CCCCC1 CHEMBL4514524 IC50 132.0 nM
Cn1c(=O)n(C2CC2)c2c3cc(-c4cnc5[nH]ccc5c4)ccc3ncc21 CHEMBL3914044 IC50 135.0 nM
NC(=O)c1cnc2ccc(-c3cccnc3)cc2c1NC1CCCC1 CHEMBL4578468 IC50 137.0 nM
COCc1ccc(-c2cc3c(cc2F)ncc2c3n([C@H]3C[C@@H](O)C3)c(=O)n2C)cn1 CHEMBL4176135 IC50 140.0 nM
COCc1ccc(-c2ccc3nnc(C(N)=O)c(N[C@@H](C)C4CCOCC4)c3c2)cn1 CHEMBL4209427 IC50 140.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5CCN(C(C)C)CC5)cc4)cc3c21 CHEMBL5191601 IC50 158.0 nM
CCN1CCN(C(=O)Nc2ccc(-c3ccc4ncc5c(c4c3)n(CCOC)c(=O)n5C)cc2)CC1 CHEMBL5206081 IC50 159.0 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(CS(C)(=O)=O)nc5)cc4c32)C1 CHEMBL4172761 IC50 160.0 nM
COCc1ccc(-c2cc3c(cc2F)ncc2c3n([C@H]3C[C@H](OC)C3)c(=O)n2C)cn1 CHEMBL4168290 IC50 160.0 nM
COc1ccc2c(c1)Cc1cccc(-c3cc(N4CCOCC4)nc(O)n3)c1S2 CHEMBL4868624 Ki 160.0 nM
CNCCCOc1ccc(-c2ccc3ncc4nnn([C@H](C)c5ccccc5)c4c3c2)cn1 CHEMBL5401617 IC50 166.0 nM
CN(C)CCCOc1ccc(-c2ccc3ncn(-c4ccc(Cl)cc4)c3n2)cn1 CHEMBL5432120 IC50 166.0 nM
CN1CCN(CC(=O)Nc2ccc(-c3ccc4ncn(-c5cccc(NS(C)(=O)=O)c5)c4c3)cc2)CC1 CHEMBL5395018 IC50 166.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(C#N)nc4)cc3c21 CHEMBL5397731 IC50 167.0 nM
C[C@H](Nc1c(C(N)=O)cnc2ccc(-c3cccnc3)cc12)C1CCOCC1 CHEMBL4548199 IC50 168.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(F)cc4)cc3c21 CHEMBL5439217 IC50 174.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccc(CNC5CCOCC5)cc4)no3)n2)cc1 CHEMBL4444602 Ki 189.0 nM
CNCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)on2)cc1Cl CHEMBL4541587 Ki 190.0 nM
COc1ccccc1-n1cnc2ccc(-c3ccc(NC(=O)NCCN(C)C)cc3)cc21 CHEMBL5432048 IC50 197.0 nM
NC(N)=S CHEMBL260876 IC50 200.0 nM
O=C(NC(NC(=S)Nc1ccc(F)c([N+](=O)[O-])c1)C(Cl)(Cl)Cl)C(c1ccccc1)c1ccccc1 CHEMBL1221601 IC50 200.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5CCN(C)CC5)c(F)c4F)cc3c21 CHEMBL5207735 IC50 212.0 nM
Cn1c(=O)n(C2CC2)c2c3cc(-c4cnc(N)nc4)ccc3ncc21 CHEMBL3968419 IC50 216.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4ccc(C(F)(F)F)nc4)cc3c21 CHEMBL5409512 IC50 225.0 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(CO)nc5)cc4c32)C1 CHEMBL4164853 IC50 230.0 nM
CO[C@H]1C[C@@H](n2c(=O)n(C)c3cnc4cc(F)c(-c5ccc(N(C)CCN(C)C)nc5)cc4c32)C1 CHEMBL4164430 IC50 230.0 nM
COCc1ccc(-c2cc3c(cc2F)ncc2c3n([C@H]3CC[C@H](OC)CC3)c(=O)n2C)cn1 CHEMBL4171264 IC50 240.0 nM
Cn1nnc2cnc3ccc(-c4ccc(N)nc4)cc3c21 CHEMBL5406297 IC50 243.0 nM
CN(C)CCCOc1ccc(-c2ccc3ncn(-c4ccc5c(c4)CN(S(C)(=O)=O)CC5)c3n2)cn1 CHEMBL5399829 IC50 249.0 nM
C=C1C(=O)OCC1(C(=O)OCC)C(=O)OCC CHEMBL2181114 IC50 250.0 nM
C[C@@H](c1ccc(F)cc1)n1nnc2cnc3ccc(-c4ccc(N)nc4)cc3c21 CHEMBL5395130 IC50 250.0 nM
COCc1ccc(-c2ccc3nnc(C(N)=O)c(N[C@@H](C)c4ccn(C)n4)c3c2)cn1 CHEMBL4210849 IC50 260.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5ccccc5)c(NS(C)(=O)=O)c4)c3c2)cc1 CHEMBL5430296 IC50 262.0 nM
CN(C)CCNC(=O)N1CCc2cc(-c3ccc4ncn(-c5cccc(NS(C)(=O)=O)c5)c4c3)ccc21 CHEMBL5407439 IC50 264.0 nM
CN(C)CCNC(=O)Cc1ccc(-c2ccc3ncn(-c4cccc(NS(C)(=O)=O)c4)c3c2)cc1 CHEMBL5420352 IC50 280.0 nM
CC(C)C(NS(=O)(=O)c1cccc2nsnc12)C(=O)NCc1ccco1 CHEMBL1508686 Potency 281.8 nM
COc1cccc(CN2CCN(Cc3cc(OC)c(OC)cc3OC)CC2)c1 CHEMBL1436991 Potency 281.8 nM
CN(C)CCCOc1ccc(-c2ccc3ncn(C4CCCCC4)c3c2)cn1 CHEMBL5403773 IC50 283.0 nM
CNC(=O)c1ccc(-c2cnc3cnc(-c4ccccc4)cn23)cc1 CHEMBL5178407 IC50 310.0 nM
COc1cc(OC)cc(C(=O)NC2CC(C)(C)NC(C)(C)C2)c1 CHEMBL1612428 Potency 316.2 nM
O=C1Nc2ccccc2C1Cc1nc2ccccc2c(=O)n1-c1ccccc1 CHEMBL1584455 Potency 316.2 nM
Cc1ccc(-n2c(S)nnc2CC#N)c(C)c1 CHEMBL1484757 Potency 316.2 nM
CN1CCN(Cc2nc(N)nc(Nc3ccc4c(c3)OCCO4)n2)CC1 CHEMBL1327106 Potency 316.2 nM
Cc1ccc(CNC(=O)c2cccc(OCc3c(C)noc3C)c2)cc1 CHEMBL1509355 Potency 316.2 nM
C(=C/c1ccccn1)\c1ccccn1 CHEMBL67376 Potency 316.2 nM
CC1=NOC2(C1)N(C)c1ccccc1C2(C)C CHEMBL1569269 Potency 316.2 nM
COc1ccc(CNC(=O)c2cnc(C)cn2)cc1 CHEMBL1500967 Potency 316.2 nM
CN=C(S)N(CCc1c(C)[nH]c2ccc(F)cc12)Cc1ccco1 CHEMBL1608923 Potency 316.2 nM
N#Cc1ccccc1-c1cnc(N)c(C(=O)Nc2ccccc2)n1 CHEMBL1766765 IC50 320.0 nM
CNC(=O)c1nnc2ccc(-c3ccc(COC)nc3)cc2c1N[C@@H](C)C1CCOCC1 CHEMBL4205554 IC50 330.0 nM
CN1CCCC1COc1ccc(-c2ccc3ncn(-c4ccc(-c5ccccc5)cc4)c3c2)cn1 CHEMBL5434447 IC50 333.0 nM
NS(=O)(=O)c1cccc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4857669 IC50 341.0 nM
Cc1ccccc1CN1CCN(C(=O)Nc2ccc(-c3ccc4ncn(-c5cccc(NS(C)(=O)=O)c5)c4c3)cc2)CC1 CHEMBL5414536 IC50 343.0 nM
CSCCC(NC(=O)c1ccccc1Br)C(=O)NCc1ccc(F)cc1 CHEMBL1318333 Potency 354.8 nM
Oc1nc(CN2CC=C(c3ccccc3)CC2)nc2scc(-c3ccccc3)c12 CHEMBL1345480 Potency 354.8 nM
Nc1nc(N)c(N=Nc2ccc(C(=O)O)cc2)c(N)n1 CHEMBL1364266 Potency 354.8 nM
Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4cccnc4)ccc3ncc21 CHEMBL4169828 IC50 360.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4cccc(NS(=O)(=O)C5CC5)c4)c3c2)cc1 CHEMBL5394441 IC50 363.0 nM
COCc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCOCC2)c(=O)n4C)cn1 CHEMBL4167508 IC50 370.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3ccc(COC)cc3)cc12 CHEMBL4551177 IC50 373.0 nM
CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3nc4ccccc4[nH]3)n2)cc1 CHEMBL1766801 IC50 380.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5CCN(C)CC5)c(F)c4)cc3c21 CHEMBL5200256 IC50 394.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3noc(-c4ccccc4)n3)n2)cc1 CHEMBL4445532 Ki 400.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3ccncc3)cc12 CHEMBL4569880 IC50 418.0 nM
Cn1nc(C2CCOCC2)c2c3cc(-c4cncc(C(F)F)c4)ccc3ncc21 CHEMBL4870563 IC50 442.0 nM
COCc1ccc(-c2cc3c(cc2F)ncc2c3n(C3CCOCC3)c(=O)n2C)cn1 CHEMBL4162952 IC50 450.0 nM
NC(=O)c1cnc2ccc(-c3cccnc3)cc2c1NCC1CCCCC1 CHEMBL4550293 IC50 456.0 nM
COc1ccc2c(c1)C(C)(C)c1cccc(-c3cc(=O)cc(N4CCOCC4)o3)c1S2 CHEMBL4799437 IC50 480.0 nM
C[C@H](c1ccccc1)n1nnc2cnc3ccc(-c4cnc(N(C)C)nc4)cc3c21 CHEMBL5435448 IC50 482.0 nM
COCc1ccc(-c2cc3c(cc2F)ncc2c3n([C@@H](C)C3CCOCC3)c(=O)n2C)cn1 CHEMBL4170883 IC50 490.0 nM
Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4cnc(N)nc4)ccc3ncc21 CHEMBL3935310 IC50 494.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)c1ccc3c(c1)OCO3)C2(C)C CHEMBL5425498 IC50 516.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3cnn(C)c3)cc12 CHEMBL4549865 IC50 525.0 nM
COC[C@@H]1c2cc(OC)ccc2Sc2c(-c3cc(=O)cc(N4CCOCC4)o3)cccc21 CHEMBL4795477 IC50 530.0 nM
CC(C)(C#N)c1ccc(N2C(=O)OCc3cnc4ccc(-c5cnc6ccccc6c5)cc4c32)cc1 CHEMBL3334621 IC50 545.0 nM
COc1ccc(NC(=O)N2CC(C)OC(C)C2)cc1OC CHEMBL1339102 Potency 562.3 nM
CCOC(=O)N1CCC(NC(=O)Cn2cc3c(n2)CCCCC3)CC1 CHEMBL1563148 Potency 562.3 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3cccnn3)cc12 CHEMBL4585977 IC50 571.0 nM
FC(F)c1ccc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)cc1 CHEMBL4864349 IC50 581.0 nM
C=C1C(=O)OC[C@@H]1C(=O)N1Cc2cc3ccccc3nc2C1 CHEMBL2181113 IC50 600.0 nM
NC(=O)c1cnc2cc(F)c(-c3cccnc3)cc2c1NC1CCOCC1 CHEMBL4540906 IC50 606.0 nM
CCS(=O)(=O)Nc1cccc(-n2cnc3ccc(-c4ccc(NC(=O)NCCN(C)C)cc4)cc32)c1 CHEMBL5409359 IC50 613.0 nM
CN(C)CCNC(=O)Nc1ccc(-c2ccc3ncn(-c4ccc(-c5ccccc5)cc4)c3c2)cc1 CHEMBL5409243 IC50 626.0 nM
Cc1nnsc1C(=O)NCc1c(F)cccc1Cl CHEMBL398682 Potency 631.0 nM
CC(CCc1ccccc1)NC(=O)COC(=O)c1ccc(F)cc1 CHEMBL1466741 Potency 631.0 nM
CN(C)c1ccc(C2N3CC4(C)CN2CC(C)(C3)C4O)cc1 CHEMBL1495783 Potency 631.0 nM
Cc1cc(O)ccc1-c1cnc2ccccc2n1 CHEMBL576353 Potency 631.0 nM
CCN(CC)S(=O)(=O)c1ccc(C(=O)NC2CN3CCC2CC3)cc1 CHEMBL1417635 Potency 631.0 nM
COc1ccc(-c2nn(-c3ccccc3)cc2/C=C/C(=O)O)cc1[N+](=O)[O-] CHEMBL1348796 Potency 631.0 nM
COCCN(Cc1cc2cc3c(cc2nc1Cl)OCO3)C(=O)c1cccc(C)c1 CHEMBL1388724 Potency 631.0 nM
CCN1CC2C3CCC(C)(O3)C2C1 CHEMBL1523249 Potency 631.0 nM
Fc1ccc(-c2nc(-c3cccs3)no2)cc1 CHEMBL1378459 Potency 631.0 nM
COc1ccc(-c2csc(-c3ccc(O)cc3)n2)cc1 CHEMBL1348962 Potency 631.0 nM
O=C(c1cn(Cc2ccccc2F)c2ncccc12)C(F)(F)F CHEMBL1309117 Potency 631.0 nM
Cc1ccc(S(=O)(=O)N2CCOCC2)cc1C(=O)OCC(=O)NC1CCCCC1 CHEMBL1523423 Potency 631.0 nM
Cc1ccn(-c2cccc(-n3ccc(C)n3)n2)n1 CHEMBL1349408 Potency 631.0 nM
CC(=O)c1cccc(CN2CCN(CC=C(C)C)C(CCO)C2)c1 CHEMBL1418628 Potency 631.0 nM
Cc1cc(NC(=O)CN(C)S(=O)(=O)c2cccc(Cl)c2)no1 CHEMBL1429321 Potency 631.0 nM
O=C(Nc1ccc2[nH]cnc2c1)c1ccco1 CHEMBL1547504 Potency 631.0 nM
O=C(COC(=O)/C=C/c1ccc(F)cc1)NCc1ccco1 CHEMBL1586697 Potency 631.0 nM
COc1cc(C(=S)N2CCCC2)ccc1OS(=O)(=O)c1ccc(NC(C)=O)cc1 CHEMBL1508928 Potency 631.0 nM
COc1ccc2nc(O)c(CN(Cc3ccco3)Cc3nnnn3Cc3ccccc3)cc2c1 CHEMBL1367309 Potency 631.0 nM
CCCc1cc(C(=O)Nc2cc(OC)c(Cl)cc2OC)no1 CHEMBL1430610 Potency 631.0 nM
COC(=O)c1cc2ccsc2n1CC(=O)N1CCCc2ccccc21 CHEMBL1367594 Potency 631.0 nM
CCN(CC)C(=O)CN1C(=O)NC2(CCc3ccccc3C2)C1=O CHEMBL1548417 Potency 631.0 nM
O=C(NCc1ccccc1)C1(CC2CC(c3ccccc3)=NO2)CCNCC1 CHEMBL1516109 Potency 631.0 nM
Oc1ccc(-c2nccc(-c3ccc(F)cc3)n2)cc1 CHEMBL1352142 Potency 631.0 nM
Cc1cc(OCc2nc(-c3cccnc3)no2)c(C)cc1Br CHEMBL1446526 Potency 631.0 nM
Brc1ccc(-c2nn[nH]n2)cc1 CHEMBL1471025 Potency 631.0 nM
N#CC(c1ccc(Cl)cc1)c1nc2ccccc2nc1C(F)(F)F CHEMBL1312648 Potency 631.0 nM
CC(=O)c1ccc([N+](=O)[O-])c(CS(=O)(=O)c2ccc(Cl)cc2)c1 CHEMBL1407845 Potency 631.0 nM
O=[N+]([O-])c1ccc(N2CCN(c3ccccc3)CC2)nc1 CHEMBL1564701 Potency 631.0 nM
CC(C)CCN1CCC(C)(NC(=O)c2ccccc2)C1=O CHEMBL1396391 Potency 631.0 nM
O=C(NCCOc1ccccc1)C1CCC(=O)N(CCc2ccc(Cl)cc2)C1 CHEMBL1564961 Potency 631.0 nM
O=CN1CCN(C2CC(=O)N(c3ccc(Br)cc3)C2=O)CC1 CHEMBL1354005 Potency 631.0 nM
COc1ccc(C(=O)N2CCCC2(C#N)c2ccccc2)cc1[N+](=O)[O-] CHEMBL1497336 Potency 631.0 nM
CCCc1ccc(S(=O)(=O)Nc2ccc(C)c(NS(C)(=O)=O)c2)cc1 CHEMBL1575446 Potency 631.0 nM
NC(=O)c1c[nH]c2ccccc12 CHEMBL379099 Potency 631.0 nM
CC(=O)c1cccc(NC(=S)N2CCCC2)c1 CHEMBL1458181 Potency 631.0 nM
O=C(Cn1ccc(=O)[nH]c1=O)Nc1ccc(C(=O)O)c(O)c1 CHEMBL1594682 Potency 631.0 nM
O=[As](O)(c1cccs1)c1cccs1 CHEMBL1566316 Potency 631.0 nM
O=C(Oc1ccc2c(c1)OCO2)c1cc2c(s1)CCC2 CHEMBL1605033 Potency 631.0 nM
Cc1c(C)n(CCc2ccccc2)c2ncnc(NCCCN(C)C)c12 CHEMBL1556095 Potency 631.0 nM
O=C([O-])c1cc(-c2ccco2)nc2ccc(Br)cc12 CHEMBL1576064 Potency 631.0 nM
COc1ccc(OC)c(NC(=O)Cc2c(C(=O)O)n(C)c3ccccc23)c1 CHEMBL1556286 Potency 631.0 nM
CN1CCC(c2c[nH]c3ccccc23)C1 CHEMBL1340424 Potency 631.0 nM
COC(=O)c1ccncc1C(=O)Nc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1 CHEMBL1498254 Potency 631.0 nM
Cc1cc2oc(C(=O)NCc3ccncc3)c(C)c2cc1C CHEMBL1449161 Potency 631.0 nM
CCOC(=O)c1csc(N/N=C2\CCCc3ccccc32)n1 CHEMBL3196251 Potency 631.0 nM
N=c1ccn(Cc2ccc(Cl)cc2)cc1 CHEMBL1459189 Potency 631.0 nM
O=C(c1nc[nH]n1)N1CCN(c2nc(-c3ccccc3)cs2)CC1 CHEMBL1526443 Potency 631.0 nM
O=C(Cn1cnc2ccccc2c1=O)Nc1cccc(S(=O)(=O)N2CCCCC2)c1 CHEMBL1537964 Potency 631.0 nM
Brc1c(C[n+]2ccccc2)nc2ccccn12 CHEMBL1380967 Potency 631.0 nM
S=c1sc2c(N3CCOCC3)ncnc2n1-c1ccccc1 CHEMBL1577013 Potency 631.0 nM
CCOc1ccc(CCNC(=O)CSc2cc(=O)n(C)c3ccccc23)cc1OCC CHEMBL1488394 Potency 631.0 nM
COc1ccc(-c2noc(CCC(=O)O)n2)cc1 CHEMBL1421066 Potency 631.0 nM
COc1ccccc1NC(=O)COC(=O)c1ccc2c(c1)nc(C)n2-c1ccccc1 CHEMBL1568046 Potency 631.0 nM
O=C(Nc1cc(Cl)ccc1N1CCOCC1)c1ccc(F)c(S(=O)(=O)N2CCOCC2)c1 CHEMBL1553753 Potency 631.0 nM
Cc1cccc(S(=O)(=O)N2CCCc3ccccc32)c1 CHEMBL1371962 Potency 631.0 nM
CCn1cc(Br)c(C(=O)NC(=S)Nc2cc([N+](=O)[O-])ccc2C)n1 CHEMBL1538846 Potency 631.0 nM
CCOc1ccc(NC(=N)Nc2nc(O)cc(CSc3nnnn3-c3ccccc3)n2)cc1 CHEMBL1302289 Potency 631.0 nM
COc1ccc(N(CC(=O)NCCC2=CCCCC2)S(=O)(=O)c2ccccc2)cc1 CHEMBL1382170 Potency 631.0 nM
Cc1ccc(S(=O)(=O)NCC(=O)NCC(=O)N2CCN(c3ncccn3)CC2)cc1C CHEMBL1500688 Potency 631.0 nM
Cc1onc(-c2c(F)cccc2Cl)c1C(=O)N1CCN(S(C)(=O)=O)CC1 CHEMBL1539635 Potency 631.0 nM
Cc1cccc(C)c1OCC(=O)NNC(=O)CNC(=O)c1ccc(OC(F)F)cc1 CHEMBL1515031 Potency 631.0 nM
Cc1ccc2c(CN(C)Cc3cccc(Cl)c3)cc(=O)oc2c1C CHEMBL1461673 Potency 631.0 nM
O=C(COc1ccccc1[N+](=O)[O-])N1CCCc2ccccc21 CHEMBL1355259 Potency 631.0 nM
COc1ccc(Cl)cc1/C=C/c1ccc2cccc(O)c2n1 CHEMBL1423286 Potency 631.0 nM
Cc1ccc(N2C(=O)NC(=O)/C(=C/NCC3CCCO3)C2=O)c(C)c1 CHEMBL1540844 Potency 631.0 nM
CC1C=CCC2C(=O)N(c3cccc(C(=O)Nc4ccc(Br)cc4)c3)C(=O)C12 CHEMBL1304303 Potency 631.0 nM
CN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 CHEMBL1304373 Potency 631.0 nM
Cc1nn(CC(=O)NC(C)C(C)C)c(C)c1S(=O)(=O)N1CCCCC1 CHEMBL1493053 Potency 631.0 nM
COc1ccc(/C=C(/NC(=O)c2ccco2)C(=O)N2CCc3ccccc32)cc1OC CHEMBL1480859 Potency 631.0 nM
CCOC(=O)N/N=C/c1ccccc1OCc1ccc(Cl)cc1 CHEMBL3212566 Potency 631.0 nM
CCOC(=O)COc1nc(-c2ccccc2)cc(-c2ccco2)c1C#N CHEMBL1463427 Potency 631.0 nM
Cc1cccc2cc3c(NC(=O)CC(C)C)nn(C)c3nc12 CHEMBL1305207 Potency 631.0 nM
CN(C)C(=O)c1nc2ccc(Cl)cn2c1CNCc1cccc(OC(F)(F)F)c1 CHEMBL1503074 Potency 631.0 nM
COc1ccccc1CC(=O)NC(=O)c1ccccc1O CHEMBL1385191 Potency 631.0 nM
COc1ccc(-c2nn(-c3ccccc3)cc2C(=O)O)cc1 CHEMBL1454289 Potency 631.0 nM
Cc1nnc(SCC(=O)NCCOc2ccc(Cl)cc2)n1-c1ccccc1 CHEMBL1376088 Potency 631.0 nM
CN1CCN(CC(=O)Nc2ccc(S(=O)(=O)N(C)C)cc2)CC1 CHEMBL1425280 Potency 631.0 nM
COc1cc(/C=C2\C=CC(=O)O2)cc(OC)c1 CHEMBL1323910 Potency 631.0 nM
CCOc1cc(CN2CCCC(CNC(=O)c3ccc(F)cc3)C2)ccc1OC CHEMBL1306117 Potency 631.0 nM
O=C1NC(=O)N(c2ccc(Cl)cc2)C(=O)/C1=C/c1coc2ccc(O)cc2c1=O CHEMBL1542944 Potency 631.0 nM
CC(C)(C)c1cc(-c2nnc(S)n2-c2ccccc2F)[nH]n1 CHEMBL1572168 Potency 631.0 nM
O=C(CN1CCN(Cc2ccccc2)CC1)Nc1ccc(Cl)cc1 CHEMBL1464591 Potency 631.0 nM
CCN=C(S)N(CCc1c(C)[nH]c2ccc(Cl)cc12)Cc1cccnc1 CHEMBL1599449 Potency 631.0 nM
Cc1ccc(-n2nnnc2SC(C)C(=O)Nc2ccc(Cl)cn2)cc1 CHEMBL1560871 Potency 631.0 nM
CCCOC(=O)c1[nH]c2c(c1C)C(=O)CC(c1cc(OC)c(OC)c(OC)c1)C2 CHEMBL1494575 Potency 631.0 nM
Cc1ccc(Nc2nc(=O)c3cccnc3s2)c(Br)c1 CHEMBL1347154 Potency 631.0 nM
O=C(NCC1CCCO1)C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1 CHEMBL1426712 Potency 631.0 nM
CN(C)S(=O)(=O)Nc1ccccn1 CHEMBL1371711 Potency 631.0 nM
CC(C)(C)n1ncc(Oc2ccccc2[N+](=O)[O-])c(Cl)c1=O CHEMBL1416992 Potency 631.0 nM
O=C(NCc1ccccc1)c1cccnc1Sc1ccccc1 CHEMBL1443887 Potency 631.0 nM
Cc1ccc(-c2noc(CSc3nnnn3-c3ccccc3)n2)cc1 CHEMBL1561768 Potency 631.0 nM
O=C(Nc1ccc(N2CCCC2)cc1)c1ccc(Cl)cc1Cl CHEMBL1483394 Potency 631.0 nM
C/C(CCC1CC(C)OC1=O)=N\NC(N)=S CHEMBL1992234 Potency 631.0 nM
COc1ccc2oc(C(=O)Nc3nnc(C)s3)c(C)c2c1 CHEMBL1435035 Potency 631.0 nM
COc1ccc(-n2c(SC3CCOC3=O)nc3ccccc3c2=O)cc1OC CHEMBL1308025 Potency 631.0 nM
CCCSC1=C(C#N)C(c2cccs2)CC(=O)N1 CHEMBL1535091 Potency 707.9 nM
Cc1onc(-c2c(F)cccc2Cl)c1C(=O)NCc1ccc(F)cc1 CHEMBL1308434 Potency 707.9 nM
Cc1ccc2c(CN3CCOCC3)cc(=O)oc2c1C CHEMBL1378093 Potency 707.9 nM
CCN1C(=O)N(CC)C(=O)C2(Cc3ccccc3N3CCN(c4ccccc4)CC32)C1=O CHEMBL1388485 Potency 707.9 nM
COc1ccccc1CNc1ccc(Br)cn1 CHEMBL1444680 Potency 707.9 nM
CCN1CCN(c2oc(COc3ccc(Cl)cc3)nc2C#N)CC1 CHEMBL1388870 Potency 707.9 nM
COc1cccc2nc(O)c(-c3ccccc3)cc12 CHEMBL1378535 Potency 707.9 nM
O=C1c2cccc3c(O)ccc(c23)C(=O)N1c1ccc(Cl)cc1 CHEMBL1372920 Potency 707.9 nM
Cc1ccnc(NC(=O)c2ccccc2NC(=O)c2ccccc2)c1 CHEMBL1451593 Potency 707.9 nM
CC(C)c1onc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)c1[N+](=O)[O-] CHEMBL1496606 Potency 707.9 nM
CCOC(=O)NC1Cc2ccccc2C1Sc1ccccn1 CHEMBL1507485 Potency 707.9 nM
COC(=O)c1ccc(C(=O)Nc2ccc3[nH]c(-c4ccncc4)nc3c2)cc1 CHEMBL1429053 Potency 707.9 nM
N#CCCN(Cc1ccccc1)C(=O)Nc1ccc2c(c1)CCO2 CHEMBL1309676 Potency 707.9 nM
Cc1cccc(NC(=O)/C(C#N)=C/c2ccc(F)cc2)n1 CHEMBL1524106 Potency 707.9 nM
CC(C)(CN1CCN(c2ccccc2)CC1)NS(=O)(=O)c1ccccc1 CHEMBL1468405 Potency 707.9 nM
O=C(Cn1ccc(C(F)(F)F)n1)Nc1cccc(S(=O)(=O)N2CCCCC2)c1 CHEMBL1585877 Potency 707.9 nM
CCOC(=O)Cc1csc(NC(=O)CSc2nnc(C(C)C)n2C)n1 CHEMBL1350338 Potency 707.9 nM
Cc1cccc(C)c1NC(=O)CSC(=S)N1CCCC1 CHEMBL1508492 Potency 707.9 nM
CCCCC(=O)Nc1c(-c2ccc(OC)c(OC)c2)c(=O)c2ccccc2n1C CHEMBL1327340 Potency 707.9 nM
Cc1ccc2c(c1)s/c(=N\C(=O)C1CC1)n2C CHEMBL3211368 Potency 707.9 nM
O=C(c1cccnc1)C1CCCN(Cc2nc(-c3cnccn3)no2)C1 CHEMBL1351028 Potency 707.9 nM
O=C(Cc1c(Cl)cccc1Cl)NC1=NCCS1 CHEMBL1391113 Potency 707.9 nM
COc1ccc(C)cc1Nc1c2c(nc3ccccc13)CCC2 CHEMBL1327703 Potency 707.9 nM
CCOC(=O)c1cccc(N2C(=O)C3C4C=CC(CC4)C3C2=O)c1 CHEMBL1525084 Potency 707.9 nM
Cc1cc(NC(=O)Nc2cc(Cl)ccc2C)no1 CHEMBL1608622 Potency 707.9 nM
Cn1c(=O)n(C)c2cc(C(=O)Nc3ccc(Br)cc3)ccc21 CHEMBL1312056 Potency 707.9 nM
CC(NC(=O)CNC(=O)c1cccc(Cl)c1)c1ccccc1 CHEMBL1509813 Potency 707.9 nM
CCCCN(CCO)c1ncnc2sc(-c3ccccc3)cc12 CHEMBL1312467 Potency 707.9 nM
COCCN(C(=O)CNC(=O)c1cccs1)C(C(=O)NC1CCCC1)c1cccs1 CHEMBL1510214 Potency 707.9 nM
CCCCCC/C=C/c1ccc([C@H]2[C@H]3C=CC[C@@H](C)[C@@H]3C(=O)N2Cc2ccccc2)c(F)c1 CHEMBL1510351 Potency 707.9 nM
O=C(Cn1c(=O)c2c3c(sc2n(Cc2ccccc2)c1=O)CCCC3)NCCO CHEMBL1549446 Potency 707.9 nM
CCn1c2ccccc2c2c3ncc4cccn4c3ccc21 CHEMBL1328213 Potency 707.9 nM
Cc1ccc(NC(=O)CSc2nnc([C@H](C)NC(=O)OC(C)(C)C)o2)c(C)c1 CHEMBL1352629 Potency 707.9 nM
O=C(Cc1ccccc1)N1CCN(Cc2cccc(Cl)c2)CC1 CHEMBL1471045 Potency 707.9 nM
Cc1ccc(NC(S)=NCCCN2CCOCC2)cc1C CHEMBL1588448 Potency 707.9 nM
O=C1NC(NS(=O)(=O)c2ccc(Cl)cc2)(C(F)(F)F)C(=O)N1CCc1ccccc1 CHEMBL1392981 Potency 707.9 nM
COc1cccc(C(O)c2nc3ccccc3n2C(C)C)c1OC CHEMBL1486615 Potency 707.9 nM
CCCCOc1ccc(CON(C(C)=O)C(C)=O)cc1Cl CHEMBL1526017 Potency 707.9 nM
COC(=O)c1c(NC(=O)C(C)(C)C)sc2c1C(C(=O)OC)CC2 CHEMBL1525975 Potency 707.9 nM
CCN=C(S)N(CCc1c(C)[nH]c2ccc(F)cc12)Cc1cccnc1 CHEMBL1511548 Potency 707.9 nM
O=C(CSc1ccccn1)N/N=C/c1cc([N+](=O)[O-])ccc1O CHEMBL3194704 Potency 707.9 nM
Cc1cc(NC(=O)Nc2ccccc2)n(C(C)(C)C)n1 CHEMBL1354110 Potency 707.9 nM
CCc1ccc(NC(=O)CNCc2ccc(OC)c(OC)c2)cc1 CHEMBL1594143 Potency 707.9 nM
COc1cccc(CNC(=O)C(CC(C)C)NC(=O)c2ccccc2C)c1 CHEMBL1418815 Potency 707.9 nM
COc1ccc(OC)c(S(=O)(=O)N/N=C\c2c[nH]c3ccccc23)c1 CHEMBL3193059 Potency 707.9 nM
Cc1ccc(NC(=O)CSc2nnc(CNC(=O)c3ccco3)n2C)c(C)c1 CHEMBL1526642 Potency 707.9 nM
C=CCOC(=O)Nc1c(C(=O)OC)[nH]c2ccc(Cl)cc12 CHEMBL1409188 Potency 707.9 nM
CC(C)CCNC(=O)c1cc(-c2cccs2)nc2ccccc12 CHEMBL1438151 Potency 707.9 nM
CCOC(=O)c1ccccc1NC(=O)c1ccc2[nH]cnc2c1 CHEMBL1359144 Potency 707.9 nM
CC(C)CNS(=O)(=O)c1cc(C(=O)O)c(Cl)cc1Cl CHEMBL1486440 Potency 707.9 nM
CC(C)Oc1ccccc1C1NC(=O)CCC1[N+](=O)[O-] CHEMBL1407984 Potency 707.9 nM
O=C(O)CCCC(=O)N1N=C(c2ccccc2)CC1c1cccs1 CHEMBL1359268 Potency 707.9 nM
COCCN=C(S)N1CCN(C)CC1 CHEMBL1556160 Potency 707.9 nM
O=C(O)CSc1nnc(C2COc3ccccc3O2)n1-c1ccccc1 CHEMBL1603965 Potency 707.9 nM
CN(C)S(=O)(=O)c1cccc(C(=O)/N=C2/N=C3C=CC(Cl)=CN3Cc3ccccc32)c1 CHEMBL3209647 Potency 707.9 nM
c1ccc2c(c1)nc(Nc1ccc(N3CCCCC3)cc1)c1nncn12 CHEMBL1537118 Potency 707.9 nM
Nc1[nH]nc2c1C1(CCCCC1)Cc1ccccc1-2 CHEMBL1319701 Potency 707.9 nM
O=C(COc1ccc([N+](=O)[O-])cc1)NNC(=O)Nc1ccccc1F CHEMBL1380216 Potency 707.9 nM
O=C(C[n+]1nc(CNc2ccc(Br)cc2)n2c1CCCCC2)c1ccc([N+](=O)[O-])cc1 CHEMBL1458722 Potency 707.9 nM
CCN(CC)S(=O)(=O)c1ccc(Cl)c(NC(=O)CCCCl)c1 CHEMBL1517256 Potency 707.9 nM
CC(C)(C)n1nc2c(c1NC(=O)C1CC(=O)N(c3ccc(Cl)cc3)C1)CS(=O)(=O)C2 CHEMBL1319862 Potency 707.9 nM
O=[N+]([O-])c1ccc(C2=NN(c3ccccc3)C(c3ccco3)C2)cc1 CHEMBL1526126 Potency 707.9 nM
COc1ccc(OC)c(C2CC(c3ccccc3)=NN2C(S)=Nc2ccccc2)c1 CHEMBL1498597 Potency 707.9 nM
O=c1ccc2c(-c3ccccc3)c3ccc(O)cc3oc-2c1 CHEMBL1605743 Potency 707.9 nM
COc1cc2c(cc1OC)CN(CC(=O)Nc1ccc(F)cc1)CC2 CHEMBL1449492 Potency 707.9 nM
CC(C)c1ccc(S(=O)(=O)/N=C2\C=C(NS(=O)(=O)c3ccccc3)C(=O)c3ccccc32)cc1 CHEMBL3186541 Potency 707.9 nM
N#CC1c2ccccc2C=CN1C(=O)c1ccccc1 CHEMBL1329005 Potency 707.9 nM
COc1ccccc1Nc1nc(N)nc(CN2CCN(Cc3ccc4c(c3)OCO4)CC2)n1 CHEMBL1478532 Potency 707.9 nM
Sc1nnc(Cn2c(-c3ccccn3)nc3ccccc32)n1-c1ccc2c(c1)OCCO2 CHEMBL1381292 Potency 707.9 nM
COc1ccc(COCC(O)CN2CCN(S(=O)(=O)c3ccc(C(C)C)cc3)CC2)cc1 CHEMBL1478757 Potency 707.9 nM
O=C(COC(=O)c1ccccc1)NC1CCCC1 CHEMBL1538444 Potency 707.9 nM
Cc1nn2c(=O)cc(CSc3nc4ccccc4[nH]3)nc2s1 CHEMBL1301856 Potency 707.9 nM
CCn1ncc(C2=NOC(C(=O)N3CCC(C(N)=O)CC3)C2)c1C CHEMBL1518313 Potency 707.9 nM
COc1ccccc1OC(=O)Nc1ccc(Cl)cc1 CHEMBL1320891 Potency 707.9 nM
COc1cc(CCC(C)NCc2ccccc2)ccc1O CHEMBL1302256 Potency 707.9 nM
COC(=O)N/N=C/c1ccccc1OCCOc1ccc(OC)cc1 CHEMBL3207809 Potency 707.9 nM
CCN=C(S)N(CCc1c(C)[nH]c2ccccc12)Cc1cccnc1 CHEMBL1461107 Potency 707.9 nM
COc1ccccc1-n1c(SCC(N)=O)nc2sc3c(c2c1=O)CCC3 CHEMBL1342924 Potency 707.9 nM
CCN1CCN(C(c2ccc(C(F)(F)F)cc2)c2ccc3cccnc3c2O)CC1 CHEMBL1422849 Potency 707.9 nM
c1ccc2nc3c(nc2c1)OCC1CCCCN31 CHEMBL1461600 Potency 707.9 nM
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CSc3nncs3)CC2)cc1 CHEMBL1383301 Potency 707.9 nM
COc1ccc(Cl)cc1NC(=O)CN(C)C(=O)c1sccc1-c1ccccc1 CHEMBL1552048 Potency 707.9 nM
Cn1cc(/C=N/NC(N)=S)c2ccccc21 CHEMBL1818881 Potency 707.9 nM
Cn1c(CNC(=O)OC(C)(C)C)nnc1SCc1c(Cl)cccc1Cl CHEMBL1570839 Potency 707.9 nM
COc1cc(/C=C2/CC/C(=C/c3ccc(O)c(OC)c3)C2=O)ccc1O CHEMBL1322375 Potency 707.9 nM
CN(C)CCCNCC(=O)c1c(-c2ccccc2)n(C)c2ccccc12 CHEMBL1532055 Potency 707.9 nM
O=C(c1ccccc1)c1coc2ccc(O)c(Cl)c12 CHEMBL1384158 Potency 707.9 nM
COc1ccc(N=NC2C(=O)N(c3ccccc3)N=C2C)cc1 CHEMBL1571090 Potency 707.9 nM
Cc1nnc(SCC(=O)NC(=O)Nc2ccc3c(c2)OCCO3)n1N CHEMBL1453532 Potency 707.9 nM
Nc1ccc(S(=O)(=O)N2CCCC2C(=O)O)cc1 CHEMBL1488867 Potency 707.9 nM
O=C(COc1coc(CN2CCN(c3ccccc3)CC2)cc1=O)Nc1ccc(F)cc1 CHEMBL1335308 Potency 707.9 nM
Cc1cc(C)c2c(Cn3ccnc3)cc(=O)oc2c1 CHEMBL1414897 Potency 707.9 nM
CN(CCc1ccccn1)C(=O)c1cc(COc2ccc(F)cc2F)on1 CHEMBL1503156 Potency 707.9 nM
CCN1C/C(=C/c2sccc2C)c2nc3ccccc3c(C(=O)O)c2C1 CHEMBL1335941 Potency 707.9 nM
Cc1ccc(NC(=O)c2cc(=O)c3ccccc3o2)cc1S(=O)(=O)N1CCCCC1 CHEMBL1493793 Potency 707.9 nM
Cc1ccc(N(CC(O)CN2C(=O)NC(C)(C)C2=O)S(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL1335912 Potency 707.9 nM
Fc1cccc(CSc2nc3cc(Cl)c[nH]c-3n2)c1 CHEMBL1581312 Potency 707.9 nM
Cc1ccc(CN2CCN(C(=O)CC(C)C)CC2)cc1 CHEMBL1567711 Potency 707.9 nM
N#CCN1C(=O)C(=O)N(Cc2cccc(Cl)c2)C1=O CHEMBL1503595 Potency 707.9 nM
c1ccc(OCc2nnc3sc(C4COc5ccccc5O4)nn23)cc1 CHEMBL1481770 Potency 707.9 nM
CN(C)c1nc(N2CCN(c3ccc(F)cc3)CC2)c(C#N)c(=O)o1 CHEMBL1464198 Potency 707.9 nM
O=c1c2cc(Br)ccc2nc(-c2ccccc2)n1O CHEMBL1503699 Potency 707.9 nM
COc1ccc2c(c1)c(/N=N/C(=N)S)c(O)n2CC(=O)c1ccccc1 CHEMBL2369260 Potency 707.9 nM
O=C1c2cccc3cccc(c23)N1Cc1ccc(F)cc1 CHEMBL1425512 Potency 707.9 nM
COC(=O)c1sccc1NC(=O)Nc1ccc(C)cc1 CHEMBL1599090 Potency 707.9 nM
COC1=C(N)C(=O)c2nc(-c3nc(C(=O)O)c(C)c(-c4ccc(OC)c(OC)c4O)c3N)ccc2C1=O CHEMBL11417 Potency 707.9 nM
COc1ccc(-c2ccc(CCC(=O)O)n2-c2ccccc2O)cc1 CHEMBL1489748 Potency 707.9 nM
O=C(O)c1ccc(/C=C/c2nc(O)c3ccccc3n2)cc1 CHEMBL1376522 Potency 707.9 nM
CCOc1cc(/C=C/c2nc(O)c3ccccc3n2)ccc1O CHEMBL1324351 Potency 707.9 nM
Cc1c(Cl)c([N+](=O)[O-])nn1CCCC(=O)O CHEMBL1504587 Potency 707.9 nM
CC(C)(CO)NC(=O)c1ccc2c(c1)C(=O)c1ccccc1-2 CHEMBL1582405 Potency 707.9 nM
O=C(COC(=O)/C=C/c1ccco1)NCc1ccccc1Cl CHEMBL1386743 Potency 707.9 nM
CCOC(=O)CN1C(=O)C(=O)N(Cc2c(F)cccc2Cl)C1=O CHEMBL1465120 Potency 707.9 nM
Cc1ccc(SC(CC(=O)c2ccc(F)cc2)C(=O)O)cc1 CHEMBL1416350 Potency 707.9 nM
Cn1cc(C(=O)c2ccc(F)cc2)cc1C=O CHEMBL1582444 Potency 707.9 nM
C1=C(N2CCOCC2)/C(=C/c2nc3ccccc3[nH]2)CC1 CHEMBL1505049 Potency 707.9 nM
O=C(c1ccc(COc2ccc(Br)cc2)o1)N1N=C(C(F)F)CC1(O)C(F)F CHEMBL1495010 Potency 707.9 nM
Cc1ccc(NC(=O)NC(=O)N(C(C)C)S(C)(=O)=O)nc1 CHEMBL1307236 Potency 707.9 nM
CC1(C)C(C=C(Cl)Cl)C1C(=O)N/N=C/c1ccccc1F CHEMBL3191345 Potency 707.9 nM
CC(C)Nc1nc(Oc2ccc(=O)n(-c3ccccc3)n2)nc(N(C)C)n1 CHEMBL1387258 Potency 707.9 nM
CCCNC(=O)c1c(N)n(CC2CCCO2)c2nc3ccccc3nc12 CHEMBL1307406 Potency 707.9 nM
O=C(Cn1nc(Cc2cccnc2)c2ccccc2c1=O)Nc1ccccc1F CHEMBL1337287 Potency 707.9 nM
Cc1ccc(NC(=O)c2cc3ccccc3oc2=N)cc1 CHEMBL1443812 Potency 707.9 nM
Cc1ccc2cc(CN(C(=O)c3cccs3)c3ccccc3)c(O)nc2c1 CHEMBL1583002 Potency 707.9 nM
COc1ccc(/C=N/Nc2cc(C)nc(N3CCOCC3)n2)cc1 CHEMBL3194856 Potency 707.9 nM
O=C1C2C3C=CC(C4CC34)C2C(=O)N1c1cc(Cl)ccn1 CHEMBL1337436 Potency 707.9 nM
COc1cc([N+](=O)[O-])ccc1NC(=O)Oc1ccc(NC(C)=O)cc1 CHEMBL1561788 Potency 707.9 nM
O=C(CCC(=O)c1ccc(F)cc1)Nc1cccc(Br)c1 CHEMBL1456234 Potency 707.9 nM
CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3nc4ccccc4s3)n2)cc1 CHEMBL1766803 IC50 720.0 nM
C[C@@H](Nc1c(C(N)=O)cnc2ccc(-c3cccnc3)cc12)C1CCOCC1 CHEMBL4544394 IC50 730.0 nM
O=C(O)CCC(=O)NN1C(=O)c2ccccc2NC1c1ccco1 CHEMBL1496781 Potency 794.3 nM
N#Cc1c(-c2ccccc2)cc(-c2ccccc2)nc1O CHEMBL1531341 Potency 794.3 nM
O=C1C=C(O)c2c(O)cccc2C1=O CHEMBL1576702 Potency 794.3 nM
COc1ccccc1C(=O)OCC(=O)NC1CCCC1 CHEMBL1556881 Potency 794.3 nM
COc1ccc(C(=O)CSc2nc3ccc[nH]c-3n2)cc1OC CHEMBL1302138 Potency 794.3 nM
CCN1C(=O)C(=NNc2cccc(S(=O)(=O)N(CC)CC)c2)C(=O)N(CC)C1=S CHEMBL1342460 Potency 794.3 nM
COc1ccccc1C(=O)Nc1cccc(S(=O)(=O)N2CCCC2)c1 CHEMBL1579767 Potency 794.3 nM
Cc1[nH]c2c(C)cccc2c1CN1CCC(CO)(Cc2ccccc2)CC1 CHEMBL1344856 Potency 794.3 nM
COc1cccc(Cn2c(N)c(C#N)c3nc4ccccc4nc32)c1OC CHEMBL1454636 Potency 794.3 nM
NS(=O)(=O)c1cccc(NC(=O)COC(=O)Cc2ccc(S(=O)(=O)N3CCCCC3)s2)c1 CHEMBL1404870 Potency 794.3 nM
CCOC(=O)NCCCOc1cc2c(-n3nc(-c4ccccn4)nc3N)ncnc2cc1OC CHEMBL3765373 IC50 800.0 nM
COc1cc2ncnc(-n3nc(-c4ccccn4)nc3N)c2cc1OCCNC(=O)OC(C)(C)C CHEMBL3763939 IC50 800.0 nM
COc1cc2ncnc(-n3nc(-c4ccccn4)nc3N)c2cc1OCCCCNC(=O)OC(C)(C)C CHEMBL3764231 IC50 800.0 nM
CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3nc4ccccc4o3)n2)cc1 CHEMBL1766802 IC50 840.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5CCN(C)CC5)c(F)c4Cl)cc3c21 CHEMBL5200053 IC50 885.0 nM
Cn1ncnc2c(=O)n(C)c(=O)nc1-2 CHEMBL578512 Potency 891.3 nM
CN=C(S)N(CCc1c(C)[nH]c2ccc(Cl)cc12)Cc1cccnc1 CHEMBL1392746 Potency 891.3 nM
COc1ccc(C(CNC(=O)C(Cc2ccccc2)NC(N)=O)N(C)C)cc1 CHEMBL1392786 Potency 891.3 nM
Cc1cc(C)n(-c2nc(NCCCN(C)C)c3c4c(sc3n2)CCCC4)n1 CHEMBL1487117 Potency 891.3 nM
O=C(N/N=C/c1cccc(Cl)c1)C(c1ccncc1)N1CCOCC1 CHEMBL3190372 Potency 891.3 nM
COc1ccc(/C=N/NC(=O)c2sc3nc(C)cc(C)c3c2N)cc1 CHEMBL3208838 Potency 891.3 nM
COC(=O)c1ccccc1OC(=O)c1cc2ccccc2oc1=O CHEMBL1519568 Potency 891.3 nM
O=C(CCN1C(=O)/C(=C/c2ccccc2Cl)SC1=S)NNC(=O)c1cccnc1 CHEMBL1532541 Potency 891.3 nM
CCOC(=O)/C(C#N)=C\c1cn(C)c2ccccc12 CHEMBL1520754 Potency 891.3 nM
COc1cc2ncnc(-n3nc(-c4ccccn4)nc3N)c2cc1OCCCNC(=O)OC(C)(C)C CHEMBL3763565 IC50 900.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3ccnnc3)cc12 CHEMBL4535526 IC50 908.0 nM
COCCn1c(=O)n(C)c2cnc3ccc(-c4ccc(NC(=O)N5CCC(N(C)C)CC5)cc4)cc3c21 CHEMBL5171662 IC50 945.0 nM
NC(=O)c1cnc2ccc(-c3cccnc3)cc2c1NC1CCOCC1 CHEMBL4174323 IC50 950.0 nM
FC(F)c1cccc(-c2ccc3ncc4nnc(C5CCOCC5)n4c3c2)c1 CHEMBL4877926 IC50 951.0 nM