C[C@@H]1COCCN1c1nc(-c2c(F)ncc3[nH]ccc23)cc2c1ncn2C CHEMBL3355476 IC50 0.1 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccc(CNC5CCOCC5)cc4)no3)n2)cc1 CHEMBL4444602 Ki 0.14 nM
CNCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)on2)cc1 CHEMBL3989870 Ki 0.165 nM
C[C@@H]1COCCN1c1nc(-c2cncc3[nH]ccc23)cc2c1ncn2[C@@H](C)S(C)(=O)=O CHEMBL3355474 IC50 0.2 nM
CCNCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)on2)cc1 CHEMBL4533440 Ki 0.21 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccc(CN)cc4)no3)n2)cc1 CHEMBL4443525 Ki 0.27 nM
C[C@@H]1Cn2ncc(-c3ccc(S(C)(=O)=O)cc3)c2CN1c1ccnc2[nH]ccc12 CHEMBL3355072 IC50 0.3 nM
C[C@@H]1Cn2ncc(C3CCN(S(C)(=O)=O)CC3)c2CN1c1cc(Cl)nc2[nH]ccc12 CHEMBL3355074 IC50 0.4 nM
C[C@@H]1COCCN1c1nc(-c2cncc3[nH]ccc23)cc2c1ncn2C CHEMBL3355475 IC50 0.4 nM
CN(C)S(=O)(=O)c1ccc(-c2cnc3ccc(-c4ccnc5[nH]ccc45)nn23)cc1 CHEMBL3355069 IC50 0.5 nM
C[C@@H]1Cn2ncc(-c3ccc(S(=O)(=O)N(C)C)cc3)c2CN1c1ccnc2[nH]ccc12 CHEMBL3355071 IC50 0.5 nM
C[C@@H]1COCCN1c1nc(-c2nncc3[nH]ccc23)cc2c1ncn2C CHEMBL3355480 IC50 0.5 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccc([C@@H]5COCCN5)cc4)no3)n2)cc1 CHEMBL3642117 Ki 0.503 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccc([C@@H](C)N)cc4)no3)n2)cc1 CHEMBL4566104 Ki 0.53 nM
CNCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)on2)c(Cl)c1 CHEMBL4448538 Ki 0.75 nM
CN(C)S(=O)(=O)c1ccc(-c2cnn3c2CN(c2ccnc4[nH]ccc24)CC3)cc1 CHEMBL3355070 IC50 1.0 nM
C[C@@H]1Cn2ncc(C3CCN(S(C)(=O)=O)CC3)c2CN1c1ccnc2[nH]ccc12 CHEMBL3355073 IC50 1.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)cc2c1ncn2CS(C)(=O)=O CHEMBL3355473 IC50 1.0 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-n2c(N)nc3ccccc32)n1 CHEMBL4288033 IC50 1.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3nnc(-c4ccccc4)s3)n2)cc1 CHEMBL4434665 Ki 1.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccccc4)no3)n2)cc1 CHEMBL4440048 Ki 1.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3nnc(-c4ccccc4)o3)n2)cc1 CHEMBL4467820 Ki 1.0 nM
C[C@@H]1COCCN1c1nc(-n2c(N)nc3ccccc32)nc2c(S(C)(=O)=O)csc12 CHEMBL5394792 IC50 1.0 nM
C[C@@H]1COCCN1c1nc(-n2c(N)nc3cc(F)ccc32)nc2c(S(C)(=O)=O)csc12 CHEMBL5417125 IC50 1.2 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccc([C@H](C)N)cc4)no3)n2)cc1 CHEMBL4467848 Ki 1.24 nM
CNc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)c2scc(S(C)(=O)=O)c2n1 CHEMBL5434673 IC50 1.5 nM
C[C@@H]1Cn2ncc(C3CCN(S(C)(=O)=O)CC3)c2CN1c1ccnc2[nH]cnc12 CHEMBL3352844 IC50 2.0 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-c2cncc3[nH]ccc23)n1 CHEMBL4281240 IC50 2.0 nM
CNc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)cc(C2(S(C)(=O)=O)CC2)n1 CHEMBL4291436 IC50 2.0 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-n2c(N)nc3cc(F)ccc32)n1 CHEMBL4286105 IC50 2.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc(-c4ccccc4)on3)n2)cc1 CHEMBL4530813 Ki 2.0 nM
C[C@@H]1COCCN1c1cc(C(C)(O)C(C)(C)C)c2ccnc(-c3ccn[nH]3)c2n1 CHEMBL4635442 IC50 2.0 nM
C[C@@H]1COCCN1c1nc(-n2c(N)nc3c(F)cccc32)nc2c(S(C)(=O)=O)csc12 CHEMBL5397045 IC50 2.0 nM
CC(=O)N1Cc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C1(C)C CHEMBL5424025 IC50 2.0 nM
CCC(=O)N1Cc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C1(C)C CHEMBL5432859 IC50 2.0 nM
C[C@@H]1COCCN1c1nc(-n2cnc3ccccc32)nc2c(S(C)(=O)=O)csc12 CHEMBL5438872 IC50 2.3 nM
CNCc1ccc(-c2cc(-c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)on2)cc1Cl CHEMBL4541587 Ki 2.4 nM
C=S(N)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(-n3c(N)nc4ccccc43)n2)CC1 CHEMBL3648331 IC50 2.578 nM
C[C@@H]1COCCN1c1nc(-n2c(C(F)F)nc3ccccc32)nc2c(S(C)(=O)=O)csc12 CHEMBL5400072 IC50 2.8 nM
CNc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)c2scc(S(=O)(=O)C3CC3)c2n1 CHEMBL5421836 IC50 2.8 nM
C[C@@H]1COCCN1c1nc(-c2cc(C(F)(F)F)cc3[nH]ccc23)nc2c(S(C)(=O)=O)csc12 CHEMBL5399336 IC50 2.9 nM
CC(C)(c1cc(N2CCOCC2)nc(-c2cccc3[nH]ccc23)n1)S(C)(=O)=O CHEMBL2325703 IC50 3.0 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-n3c(N)nc4ccccc43)n2)CC1 CHEMBL4291783 IC50 3.0 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-c2cccc3[nH]ccc23)n1 CHEMBL2325697 IC50 3.0 nM
COc1ccc(C(=O)N2Cc3c(N4CCOC[C@H]4C)nc(-c4cccc5[nH]ccc45)nc3C2(C)C)cc1 CHEMBL5422058 IC50 3.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)c1cccc(S(C)(=O)=O)c1)C2(C)C CHEMBL5423608 IC50 3.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c(S(C)(=O)=O)csc12 CHEMBL5423686 IC50 3.1 nM
C[C@@H]1COCCN1c1nc(-c2cc(F)cc3[nH]ccc23)nc2c(S(C)(=O)=O)csc12 CHEMBL5417397 IC50 3.1 nM
Cc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)c2scc(S(C)(=O)=O)c2n1 CHEMBL5418001 IC50 3.5 nM
C[C@@H]1COCCN1c1nc(-c2cc(Cl)cc3[nH]ccc23)nc2c(S(C)(=O)=O)csc12 CHEMBL5406933 IC50 3.6 nM
C[C@@H]1COCCN1c1nc(-n2c(N)nc3ccc(F)cc32)nc2c(S(C)(=O)=O)csc12 CHEMBL5414136 IC50 3.7 nM
C[C@H]1COCCN1c1cc(C2([S@@](C)(=N)=O)CC2)nc(-c2ccnc3[nH]ccc23)n1 CHEMBL3956836 IC50 3.747 nM
CCc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)c2scc(S(C)(=O)=O)c2n1 CHEMBL5419522 IC50 3.8 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)CCOCC1 CHEMBL2325705 IC50 4.0 nM
C[C@@H]1COCCN1c1cc(C2([S@](C)(=N)=O)CC2)nc(-c2cc[nH]c3nccc2-3)n1 CHEMBL4285417 IC50 4.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3ncc(-c4ccccc4)o3)n2)cc1 CHEMBL4558884 Ki 4.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766793 Ki 4.0 nM
COc1cccc(C(=O)N2Cc3c(N4CCOC[C@H]4C)nc(-c4cccc5[nH]ccc45)nc3C2(C)C)c1 CHEMBL5427147 IC50 4.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)c1ccc3c(c1)OCCO3)C2(C)C CHEMBL5415921 IC50 4.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)c1ccc(S(C)(=O)=O)cc1)C2(C)C CHEMBL5408725 IC50 4.0 nM
CC(=O)c1cccc(C(=O)N2Cc3c(N4CCOC[C@H]4C)nc(-c4cccc5[nH]ccc45)nc3C2(C)C)c1 CHEMBL5412749 IC50 4.0 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=N)=O)CC2)nc(-c2ccnc3[nH]ccc23)n1 CHEMBL5184230 IC50 4.0 nM
CCS(=O)(=O)c1csc2c(N3CCOC[C@H]3C)nc(-n3c(NC)nc4ccccc43)nc12 CHEMBL5431164 IC50 4.5 nM
C[C@@H]1COCCN1c1nc(-c2c(F)ncc3[nH]ccc23)nc2c(S(C)(=O)=O)csc12 CHEMBL5416256 IC50 4.7 nM
O=S(=O)(c1ccccc1)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)CC1 CHEMBL2325711 IC50 5.0 nM
CS(=O)(=O)Cn1cnc2c(N3CCOCC3)nc(-c3cccc4[nH]ccc34)cc21 CHEMBL3355472 IC50 5.0 nM
Nc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2[C@H]1C[C@H](N2CCC2)C1 CHEMBL551064 Kd apparent 5.0 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-c2ccnc3[nH]ccc23)n1 CHEMBL4286472 IC50 5.0 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cncc4[nH]ccc34)n2)CC1 CHEMBL4278556 IC50 5.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3noc(-c4ccccc4)n3)n2)cc1 CHEMBL4445532 Ki 5.0 nM
C[C@@H]1COCCN1c1cc(N2CCN(S(C)(=O)=O)CC2)c2ccnc(-c3ccn[nH]3)c2n1 CHEMBL4638048 IC50 5.0 nM
C[C@@H]1COCCN1c1nc(-c2c[nH]c3ccccc23)nc2c(S(C)(=O)=O)csc12 CHEMBL5402654 IC50 5.0 nM
COc1cccc(C(=O)N2CCc3c(N4CCOC[C@H]4C)nc(-c4cccc5[nH]ccc45)nc3C2(C)C)c1 CHEMBL5416225 IC50 5.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)c1ccc3c(c1)OCO3)C2(C)C CHEMBL5425498 IC50 5.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)c1ccc(OC(F)F)cc1)C2(C)C CHEMBL5423097 IC50 5.0 nM
C[C@@H]1COCCN1c1nc(-c2ccnc3[nH]ccc23)nc2c(S(C)(=N)=O)csc12 CHEMBL5395096 IC50 5.4 nM
CNc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)c2scc(S(C)(=N)=O)c2n1 CHEMBL5422586 IC50 5.5 nM
CNc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)cc(C2([S@](C)(=N)=O)CC2)n1 CHEMBL3648329 IC50 5.607 nM
CNc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)c2scc(S(=O)(=O)C(C)C)c2n1 CHEMBL5422401 IC50 5.7 nM
C[C@@H]1COCCN1c1nc(-c2ccnc3[nH]ccc23)nc2c(S(C)(=O)=O)csc12 CHEMBL5425632 IC50 5.8 nM
CC(C)(C)S(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766796 IC50 6.0 nM
CC(CN(C)C)S(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766797 Ki 6.0 nM
C[C@@H]1COCCN1c1nc(-c2cnc(N)nc2)cc2c1ncn2CS(C)(=O)=O CHEMBL3355478 IC50 6.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cn(-c4ccccc4)nn3)n2)cc1 CHEMBL3695214 Ki 6.0 nM
C=CC(=O)N1CCc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C1(C)C CHEMBL5412022 IC50 6.0 nM
CC(=O)c1ccc(C(=O)N2Cc3c(N4CCOC[C@H]4C)nc(-c4cccc5[nH]ccc45)nc3C2(C)C)cc1 CHEMBL5412393 IC50 6.0 nM
CNc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)c2scc(P(C)(C)=O)c2n1 CHEMBL5432830 IC50 6.2 nM
CCP(=O)(CC)c1csc2c(N3CCOC[C@H]3C)nc(-n3c(NC)nc4ccccc43)nc12 CHEMBL5402268 IC50 6.2 nM
CS(=O)(=O)C1(c2cc(N3CC4CCC(C3)O4)nc(-c3cccc4[nH]ccc34)n2)CC1 CHEMBL2325699 IC50 7.0 nM
C[C@@H]1COCCN1c1cc(-c2ccnn2C)c2ccnc(-c3ccn[nH]3)c2n1 CHEMBL4647810 IC50 7.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)C1CCC1)C2(C)C CHEMBL5426255 IC50 7.0 nM
COc1ccc(C(=O)N2Cc3c(N4CCOC[C@H]4C)nc(-c4cccc5[nH]ccc45)nc3C2(C)C)cc1OC CHEMBL5396739 IC50 7.0 nM
C[C@@H]1COCCN1c1nc(-c2ccnc3[nH]ccc23)nc2c(C(C)(C)O)csc12 CHEMBL5414995 IC50 7.9 nM
CC(CCO)S(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766798 IC50 8.0 nM
Cc1cc(-c2nc(N3CCOCC3)cc(C3(S(C)(=O)=O)CC3)n2)c2cc[nH]c2c1 CHEMBL2325720 IC50 8.0 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)CC1 CHEMBL2325704 IC50 8.0 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-n2c(N)nc3ccc(F)cc32)n1 CHEMBL4294006 IC50 8.0 nM
C[C@@H]1COCCN1c1cc(-c2cccnc2F)c2ccnc(-c3ccn[nH]3)c2n1 CHEMBL4642221 IC50 8.0 nM
Nc1nn2cc(F)cnc2c1C(=O)Nc1cncc(F)c1N1CCC(C(=O)N2CCN(C3COC3)CC2)CC1 CHEMBL4650286 IC50 8.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)C1CC1)C2(C)C CHEMBL5398150 IC50 8.0 nM
CC(C)C(=O)N1Cc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C1(C)C CHEMBL5401874 IC50 8.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)C1CC1)C2(C)C CHEMBL5406541 IC50 8.0 nM
C=S(N)(=O)C(C)(C)c1cc(N2CCOC[C@H]2C)nc(-n2c(NC)nc3ccccc32)n1 CHEMBL3648334 IC50 8.428 nM
CNc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)c2scc([S+](C)[O-])c2n1 CHEMBL5424696 IC50 8.5 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)CCNCC1 CHEMBL2325706 IC50 9.0 nM
C[C@@H]1COCCN1c1cc(N(C)c2ccc(F)cc2)c2ccnc(-c3ccn[nH]3)c2n1 CHEMBL4632518 IC50 9.0 nM
CCC(=O)N1CCc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C1(C)C CHEMBL5425941 IC50 9.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)c1ccccc1)C2(C)C CHEMBL5419225 IC50 9.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)Cc1cccs1)C2(C)C CHEMBL5423544 IC50 9.0 nM
COc1ccc(C(=O)N2CCc3c(N4CCOC[C@H]4C)nc(-c4cccc5[nH]ccc45)nc3C2(C)C)cc1 CHEMBL5426919 IC50 9.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ncc23)nc2c(S(C)(=O)=O)csc12 CHEMBL5430998 IC50 9.6 nM
CCC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766795 IC50 10.0 nM
Nc1ncc(-c2ccc(S(=O)(=O)[C@@H]3CCOC3)cc2)nc1C(=O)Nc1ccccc1 CHEMBL1766799 IC50 10.0 nM
CNc1cnc2[nH]ccc2c1-c1nc2c(c(C(C)(C)O)n1)OC[C@@H]1COC[C@@H](C)N21 CHEMBL4295245 IC50 10.0 nM
CNc1nccn1-c1nc2c(c(C(C)(C)S(C)(=O)=O)n1)OC[C@@H]1COC[C@@H](C)N21 CHEMBL4287971 IC50 10.0 nM
C[C@@H]1COC[C@H]2COc3c(nc(N(C)c4ccn[nH]4)nc3C(C)(C)S(C)(=O)=O)N21 CHEMBL4282665 IC50 10.0 nM
CCNc1cnc2[nH]ccc2c1-c1nc2c(c(C(C)(C)S(C)(=O)=O)n1)OC[C@@H]1COC[C@@H](C)N21 CHEMBL4293269 IC50 10.0 nM
CNc1cnc2[nH]ccc2c1-c1nc2c(c(C(C)(C)S(C)(=O)=O)n1)OC[C@@H]1COC[C@@H](C)N21 CHEMBL4284592 IC50 10.0 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-n2c(N)nc3c(F)cccc32)n1 CHEMBL4280793 IC50 10.0 nM
Cc1nc(S(C)(=N)=O)ccc1-c1cc(N2CCOC[C@H]2C)nc2c(-c3ccn[nH]3)nccc12 CHEMBL4637776 IC50 10.0 nM
C[C@@H]1COCCN1c1cc(-c2cnc3n2CCC3)c2ccnc(-c3ccn[nH]3)c2n1 CHEMBL4633890 IC50 10.0 nM
CC(C)C(=O)N1CCc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C1(C)C CHEMBL5439160 IC50 10.0 nM
C=S(N)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(-n3c(NC)nc4cc(F)ccc43)n2)CC1 CHEMBL3648341 IC50 10.07 nM
C[C@@H]1COCCN1c1cc(C2([S@+](C)[O-])CC2)nc(-c2ccnc3[nH]ccc23)n1 CHEMBL4284359 IC50 11.0 nM
CCS(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766792 IC50 12.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)C(C)(C)C)C2(C)C CHEMBL5399603 IC50 12.0 nM
Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4cnc(N)nc4)ccc3ncc21 CHEMBL3935310 IC50 12.9 nM
C=S(N)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)n2)CC1 CHEMBL3648330 IC50 12.92 nM
CC(C)S(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)CC1 CHEMBL2325708 IC50 13.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2ccc(-c3ccnn3C)cc12 CHEMBL5178459 IC50 13.0 nM
CC(=O)N1CCc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C1(C)C CHEMBL5440718 IC50 13.0 nM
CC(=O)Nc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)c2scc(S(C)(=O)=O)c2n1 CHEMBL5413056 IC50 13.2 nM
C=S(N)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(-c3cncc4[nH]ccc34)n2)CC1 CHEMBL3648333 IC50 13.76 nM
CCCS(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766794 IC50 14.0 nM
CC(C)(C#N)c1ccc(N2C(=O)OCc3cnc4ccc(-c5cnc6ccccc6c5)cc4c32)cc1 CHEMBL3334621 IC50 14.0 nM
CC(=O)Nc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)cc(C2(S(C)(=O)=O)CC2)n1 CHEMBL4277395 IC50 14.0 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=N)=O)CC2)nc(-c2cncc3[nH]ccc23)n1 CHEMBL4211377 IC50 14.0 nM
C[C@@H]1COCCN1c1cc(C2CCOCC2)c2ccnc(-c3ccn[nH]3)c2n1 CHEMBL4636395 IC50 14.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)c1cccc(F)c1)C2(C)C CHEMBL5393965 IC50 14.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)C1CC1)C2 CHEMBL5419053 IC50 14.0 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cc(F)cc4[nH]ccc34)n2)CC1 CHEMBL2325439 IC50 15.0 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)c2ccnc(-c3ccn[nH]3)c2n1 CHEMBL4647939 IC50 15.0 nM
CC(C)C(=O)N1CCc2c(nc(-c3cccc4[nH]ccc34)nc2N2CCOC[C@H]2C)C1 CHEMBL5398694 IC50 15.0 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cc(Cl)cc4[nH]ccc34)n2)CC1 CHEMBL2325440 IC50 16.0 nM
CNCc1ccc(C2=NOC(c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)C2)cc1 CHEMBL2409217 Ki 16.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(C3CC(c4ccccc4)=NO3)n2)cc1 CHEMBL2409216 Ki 16.0 nM
C[C@@H]1COCCN1c1cc(C2([S@@+](C)[O-])CC2)nc(-c2ccnc3[nH]ccc23)n1 CHEMBL4294647 IC50 16.0 nM
C=S(N)(=O)C(C)(C)c1cc(N2CCOC[C@H]2C)nc(-n2c(NC)nc3cc(F)ccc32)n1 CHEMBL3648340 IC50 16.18 nM
CCCS(=O)(=O)c1csc2c(N3CCOC[C@H]3C)nc(-n3c(NC)nc4ccccc43)nc12 CHEMBL5431183 IC50 16.8 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-n2c(N)nc3c(Cl)cccc32)n1 CHEMBL4284450 IC50 17.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)C(C)(C)C)C2(C)C CHEMBL5399632 IC50 17.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)C1CCC1)C2(C)C CHEMBL5424546 IC50 17.0 nM
Cc1cccc(C(=O)N2CCc3c(N4CCOC[C@H]4C)nc(-c4cccc5[nH]ccc45)nc3C2(C)C)c1 CHEMBL5395664 IC50 17.0 nM
C[C@@H]1COCCN1c1nc(-c2ccnc3[nH]ccc23)nc2ccsc12 CHEMBL5419026 IC50 17.8 nM
CS(=O)(=O)C1(c2cc(C3=CCOCC3)nc(-c3cccc4[nH]ccc34)n2)CC1 CHEMBL4287961 IC50 18.0 nM
CCn1nccc1-c1ccc2nc(-c3cccc4[nH]ccc34)nc(N3CCOC[C@H]3C)c2c1 CHEMBL5179068 IC50 18.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(S(C)(=O)=O)C2(C)C CHEMBL5402160 IC50 18.0 nM
COC(=O)N1CCc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C1(C)C CHEMBL5419395 IC50 18.0 nM
CCOC(=O)N1CCc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C1(C)C CHEMBL5428095 IC50 18.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)c1ccc(F)cc1)C2(C)C CHEMBL5435065 IC50 18.0 nM
COc1cc(C(=O)N2Cc3c(N4CCOC[C@H]4C)nc(-c4cccc5[nH]ccc45)nc3C2(C)C)cc(OC)c1OC CHEMBL5395004 IC50 19.0 nM
CC(O)c1csc2c(N3CCOC[C@H]3C)nc(-c3ccnc4[nH]ccc34)nc12 CHEMBL5394774 IC50 19.2 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-n2c(N)nc3cc(Cl)ccc32)n1 CHEMBL4287852 IC50 21.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3cnc(-c4ccccc4)o3)n2)cc1 CHEMBL4473876 Ki 21.0 nM
Cn1c(=O)n(-c2ccc(C(C)(C)C#N)cc2)c2c3cc(-c4cnc5ccccc5c4)ccc3ncc21 CHEMBL1879463 IC50 21.0 nM
C[C@@H]1COCCN1c1cc(C2([S@@](C)(=N)=O)CC2)nc(-c2ccnc3[nH]ccc23)n1 CHEMBL3648328 IC50 21.82 nM
CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3nc4ccccc4s3)n2)cc1 CHEMBL1766803 IC50 22.0 nM
CCS(=O)(CC)=Nc1cc(N2CCOC[C@H]2C)nc2c(-c3ccn[nH]3)nccc12 CHEMBL4639847 IC50 22.0 nM
C[C@@H]1COCCN1c1cc(C#Cc2cccnc2)c2ccnc(-c3ccn[nH]3)c2n1 CHEMBL4635106 IC50 22.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)Cc1ccccc1)C2(C)C CHEMBL5406878 IC50 22.0 nM
CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3cc4ccccc4[nH]3)n2)cc1 CHEMBL1766804 IC50 23.0 nM
COc1cc(-c2nc(N3CCOCC3)cc(C3(S(C)(=O)=O)CC3)n2)c2cc[nH]c2c1 CHEMBL2325695 IC50 23.0 nM
CNc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)cc(C2([S@@](C)(=N)=O)CC2)n1 CHEMBL4281973 IC50 23.0 nM
CCC(=O)N1CCc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C12CCC2 CHEMBL5423295 IC50 23.0 nM
N#Cc1ccccc1-c1cnc(N)c(C(=O)Nc2ccccc2)n1 CHEMBL1766765 IC50 24.0 nM
CNc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)c2scc(SC)c2n1 CHEMBL5422986 IC50 24.2 nM
Cc1nccn1-c1cc(N2CCOC[C@H]2C)nc2c(-c3ccn[nH]3)nccc12 CHEMBL4649777 IC50 25.0 nM
Cn1nccc1-c1ccc2nc(-c3cccc4[nH]ccc34)nc(N3C4CCC3COC4)c2c1 CHEMBL5198456 IC50 25.0 nM
CS(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766779 IC50 26.0 nM
Nc1ncc(-c2ccc(C(=O)N3CCCCC3)cc2)nc1C(=O)Nc1ccccc1 CHEMBL1766789 IC50 26.0 nM
COc1ccc(-c2ccc3ncc(-c4ccc(C(N)=O)cc4)n3n2)cc1OC CHEMBL3355068 IC50 26.0 nM
c1cc(-c2cc3c(ncn3CC3CC3)c(N3CCOCC3)n2)c2cc[nH]c2c1 CHEMBL3352848 IC50 26.0 nM
CC(C)S(=O)(=O)c1ccc(-c2cnc(N)c(-c3nc(-c4ccccc4)no3)n2)cc1 CHEMBL4593939 Ki 26.0 nM
Cc1cc2c(-c3nc(N4CCOCC4)cc(C4(S(C)(=O)=O)CC4)n3)cccc2[nH]1 CHEMBL2325718 IC50 28.0 nM
CCP(=O)(CC)c1cc(N2CCOC[C@H]2C)nc2c(-c3ccn[nH]3)nccc12 CHEMBL4634477 IC50 28.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)C1CC1)C21CCC1 CHEMBL5420569 IC50 28.0 nM
C=S(N)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(-n3c(NC)nc4ccc(F)cc43)n2)CC1 CHEMBL3648339 IC50 28.99 nM
C[C@@H]1Cn2ncc(C3CCN(S(C)(=O)=O)CC3)c2CN1c1ccnc2[nH]ncc12 CHEMBL3355075 IC50 29.0 nM
CC(C)C(=O)N1CCc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C12CCC2 CHEMBL5398034 IC50 29.0 nM
CC(=O)N1CCc2c(nc(-c3cccc4[nH]ccc34)nc2N2CCOC[C@H]2C)C1 CHEMBL5418740 IC50 29.0 nM
CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3nc4ccccc4[nH]3)n2)cc1 CHEMBL1766801 IC50 30.0 nM
CS(=O)(=O)Cc1cc(N2CCOCC2)nc(-c2cccc3[nH]ccc23)n1 CHEMBL2030442 IC50 30.0 nM
C[C@@H]1COCCN1c1nc(-c2ccnc3[nH]ccc23)nc2c(C(N)=O)csc12 CHEMBL5429107 IC50 31.5 nM
Cc1noc(C)c1-c1ccc2nc(-c3cccc4[nH]ccc34)nc(N3CCOC[C@H]3C)c2c1 CHEMBL5188748 IC50 32.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)CN(C)C)C2(C)C CHEMBL5439862 IC50 32.0 nM
O=S(=O)(c1ccccn1)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)CC1 CHEMBL2325712 IC50 33.0 nM
O=S(=O)(C1CCOCC1)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)CC1 CHEMBL2325709 IC50 33.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2ccc(-c3cncn3C)cc12 CHEMBL5192680 IC50 33.0 nM
C=S(N)(=O)C(C)(C)c1cc(N2CCOC[C@H]2C)nc(-n2c(NC)nc3ccc(F)cc32)n1 CHEMBL3648338 IC50 33.13 nM
C[C@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-c2cccc3[nH]ccc23)n1 CHEMBL2325696 IC50 34.0 nM
CS(=O)(=O)Cn1cnc2c(N3C4CCC3COC4)nc(-c3cncc4[nH]ccc34)cc21 CHEMBL3355477 IC50 34.0 nM
C[C@@H]1COCCN1c1cc(C=S(C)(N)=O)nc(-c2ccnc3[nH]ccc23)n1 CHEMBL3648327 IC50 34.03 nM
Nc1ccc(-c2ccc3ncc4ccc(=O)n(-c5cccc(C(F)(F)F)c5)c4c3c2)cn1 CHEMBL1765602 EC50 35.0 nM
CC(=O)N1CCc2c(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)nc2C12CCC2 CHEMBL5433823 IC50 35.0 nM
CC(=O)c1csc2c(N3CCOC[C@H]3C)nc(-c3ccnc4[nH]ccc34)nc12 CHEMBL5419094 IC50 35.3 nM
CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3nc4ccccc4o3)n2)cc1 CHEMBL1766802 IC50 36.0 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3ccnc4[nH]ccc34)n2)CC1 CHEMBL4281158 IC50 37.0 nM
CC(C)Oc1cc(N2CCOC[C@H]2C)nc2c(-c3ccn[nH]3)nccc12 CHEMBL4636667 IC50 38.0 nM
CCC(=O)N1CCc2c(nc(-c3cccc4[nH]ccc34)nc2N2CCOC[C@H]2C)C1 CHEMBL5438125 IC50 38.0 nM
O=C(NC1CC1)c1cn2c(N3CCOCC3)nc(-c3cccc4[nH]ccc34)cc2n1 CHEMBL3355471 IC50 39.0 nM
C=S(N)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(-n3c(NC)nc4ccccc43)n2)CCOCC1 CHEMBL3648335 IC50 39.77 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cc(C(N)=O)cc4[nH]ccc34)n2)CC1 CHEMBL2325438 IC50 41.0 nM
C[C@@H]1Cc2ncn(C3CCN(S(C)(=O)=O)CC3)c2CN1c1ccnc2[nH]ccc12 CHEMBL3355079 IC50 41.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)c1ccc(OC(F)(F)F)cc1)C2(C)C CHEMBL5415262 IC50 42.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)c1cccc(Cl)c1)C2(C)C CHEMBL5428343 IC50 43.0 nM
Cn1nccc1-c1ccc2nc(-c3cccc4[nH]ccc34)nc(N3CC4CCC(C3)O4)c2c1 CHEMBL5192689 IC50 45.0 nM
O=S(=O)(C1CCNCC1)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)CC1 CHEMBL2325710 IC50 46.0 nM
C[C@@H]1COCCN1c1nc(-n2nnc3ccccc32)nc2c(S(C)(=O)=O)csc12 CHEMBL5436733 IC50 47.0 nM
CN(C)C(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1Cl CHEMBL1766790 IC50 48.0 nM
O=c1[nH]c2cnc3ccc(-c4cccnc4)cc3c2n1C1CCOCC1 CHEMBL4159181 IC50 51.0 nM
COc1ccc(C(=O)N2CCc3c(nc(-c4cccc5[nH]ccc45)nc3N3CCOC[C@H]3C)C2)cc1 CHEMBL5404032 IC50 51.0 nM
C=S(N)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(-c3cccc4[nH]ccc34)n2)CCOCC1 CHEMBL3648336 IC50 51.12 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)CN1CCN(C)CC1)C2(C)C CHEMBL5410944 IC50 52.0 nM
C[C@@H]1COCCN1c1nc(-c2ccnc3[nH]ccc23)nc2c(C#N)csc12 CHEMBL5440035 IC50 52.6 nM
CN(C)C(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766787 IC50 54.0 nM
Nc1ncc(-c2ccc(C(=O)N3CCCC3)cc2)nc1C(=O)Nc1ccccc1 CHEMBL1766788 IC50 54.0 nM
Cn1c(=O)n(C2CC2)c2c3cc(-c4cnc5[nH]ccc5c4)ccc3ncc21 CHEMBL3914044 IC50 55.3 nM
C[S+]([O-])c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766791 IC50 56.0 nM
CS(=O)(=O)c1ccc(-c2cc(N3CCOCC3)nc3c(-c4ccn[nH]4)nccc23)cc1 CHEMBL4640028 IC50 59.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3c2CCN3)nc2c(S(C)(=O)=O)csc12 CHEMBL5414755 IC50 59.2 nM
CN1CCC(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)(S(C)(=O)=O)CC1 CHEMBL2325707 IC50 61.0 nM
C=S(N)(=O)C(C)(C)c1cc(N2CCOC[C@H]2C)nc(-n2c(NC)nc3c(F)cccc32)n1 CHEMBL3648337 IC50 62.55 nM
C[C@@H]1Cn2ncc(C3CCN(S(C)(=O)=O)CC3)c2C(=O)N1c1ccnc2[nH]ccc12 CHEMBL3355080 IC50 64.0 nM
COc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCN(C(C)=O)CC2)c(=O)n4C)cn1 CHEMBL3946658 IC50 64.4 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cc(C#N)cc4[nH]ccc34)n2)CC1 CHEMBL2325724 IC50 66.0 nM
CS(=O)(=O)c1ccc(-n2nc(-c3cnc4[nH]ccc4c3)c3c(N)ncnc32)cc1 CHEMBL4207014 IC50 66.0 nM
COC(=O)N1CCC(n2c(=O)n(C)c3cnc4ccc(-c5ccc(OC)nc5)cc4c32)CC1 CHEMBL3967825 IC50 68.6 nM
COc1ncc(-c2ccc3ncc4c(c3c2)n(C2CC2)c(=O)n4C)cc1NS(=O)(=O)C1CC1 CHEMBL3970131 IC50 68.6 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CCN(C(=O)c1cccc(C(F)(F)F)c1)C2(C)C CHEMBL5431596 IC50 72.0 nM
COc1cccc(C(=O)N2CCc3c(nc(-c4cccc5[nH]ccc45)nc3N3CCOC[C@H]3C)C2)c1 CHEMBL5430168 IC50 76.0 nM
CC(C)n1nccc1-c1ccc2nc(-c3cccc4[nH]ccc34)nc(N3CCOC[C@H]3C)c2c1 CHEMBL5192206 IC50 83.0 nM
CS(=O)(=O)C1(c2cc(N3CC4CCC(C3)O4)nc(-c3cncc4[nH]ccc34)n2)CC1 CHEMBL4284647 IC50 86.0 nM
Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4cccnc4)ccc3ncc21 CHEMBL4169828 IC50 87.0 nM
Cn1nccc1-c1ccc2nc(-c3cccc4[nH]ccc34)nc(N3CCOCC3)c2c1 CHEMBL5174833 IC50 89.0 nM
C[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-n2c(N)nc3cccc(F)c32)n1 CHEMBL4277999 IC50 90.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)cc2nccn12 CHEMBL3355470 IC50 95.0 nM
c1cc(-c2cc3nccn3c(N3CCOCC3)n2)c2cc[nH]c2c1 CHEMBL3355469 IC50 96.0 nM
C[C@@H]1COCCN1c1nc(-c2cc(F)cc3[nH]ccc23)nc2ccc(-c3ccnn3C)cc12 CHEMBL5172908 IC50 96.0 nM
Nc1ncc(-c2ccc(C(=O)N3CCC3)cc2)nc1C(=O)Nc1ccccc1 CHEMBL1766786 IC50 100.0 nM
C=C(C)c1csc2c(N3CCOC[C@H]3C)nc(-c3ccnc4[nH]ccc34)nc12 CHEMBL5438078 IC50 108.5 nM
C=S(N)(=O)C1(c2cc(N3CCOC[C@H]3C)nc(-n3c(NC)nc4c(F)cccc43)n2)CC1 CHEMBL3648332 IC50 109.0 nM
NC(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766784 IC50 110.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2c1CN(C(=O)C1CC1)CC2 CHEMBL5415374 IC50 111.0 nM
CSc1nc2ccccc2n1-c1nc(N2CCOC[C@H]2C)c2scc(S(C)(=O)=O)c2n1 CHEMBL5420070 IC50 113.5 nM
C[C@@H]1COCCN1c1nc(-c2ccnc3[nH]ccc23)nc2ccc(-c3ccnn3C)cc12 CHEMBL5190917 IC50 115.0 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cccc4c3CC(=O)N4)n2)CC1 CHEMBL2325715 IC50 120.0 nM
C[C@@H]1COCCN1c1nc(-n2c(=O)[nH]c3ccccc32)nc2c(S(C)(=O)=O)csc12 CHEMBL5410167 IC50 122.7 nM
CC(C)Oc1cc(N2CCOCC2)nc2c(-c3ccn[nH]3)nccc12 CHEMBL4641384 IC50 125.0 nM
C[S+]([O-])c1ccccc1-c1cnc(N)c(C(=O)Nc2ccccc2)n1 CHEMBL1766766 IC50 130.0 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ncc34)n2)CC1 CHEMBL2325716 IC50 130.0 nM
CNC(=O)c1cc(-c2nc(N3CCOCC3)cc(C3(S(C)(=O)=O)CC3)n2)c2cc[nH]c2c1 CHEMBL2325726 IC50 140.0 nM
Nc1ncnc2c1c(-c1cnc3[nH]ccc3c1)nn2C1CCc2ccccc2C1 CHEMBL4207265 IC50 158.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3c2CC(=O)N3)nc2c(S(C)(=O)=O)csc12 CHEMBL5438263 IC50 159.2 nM
Cn1c(=O)n(C2CC2)c2c3cc(-c4cnc(N)nc4)ccc3ncc21 CHEMBL3968419 IC50 162.0 nM
CC[C@@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-c2cccc3[nH]ccc23)n1 CHEMBL2325698 IC50 170.0 nM
Nc1ncc(-c2cccnc2)nc1C(=O)Nc1ccccc1 CHEMBL1765107 IC50 180.0 nM
N#Cc1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766778 IC50 180.0 nM
CNC(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 CHEMBL1766785 IC50 180.0 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]cnc34)n2)CC1 CHEMBL2325717 IC50 180.0 nM
CS(=O)(=O)Cc1cc(N2CCOCC2)nc(-c2cccc3cc[nH]c23)n1 CHEMBL2325701 IC50 180.0 nM
CC1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2ccc(-c3cccnc3)cc12 CHEMBL5199317 IC50 183.0 nM
CS(=O)(=O)Cn1cnc2c(N3C4CCC3COC4)nc(-c3cnc(N)nc3)cc21 CHEMBL3355479 IC50 190.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2ccc(-c3ccc(=O)n(C)c3)cc12 CHEMBL5180045 IC50 194.0 nM
NC(N)=S CHEMBL260876 IC50 200.0 nM
O=C(NC(NC(=S)Nc1ccc(F)c([N+](=O)[O-])c1)C(Cl)(Cl)Cl)C(c1ccccc1)c1ccccc1 CHEMBL1221601 IC50 200.0 nM
C[C@@H]1COCCN1c1nc(-c2c[nH]c3ccccc23)nc2ccc(-c3ccnn3C)cc12 CHEMBL5186625 IC50 215.0 nM
Cc1ccc(-c2nc(N3CCOCC3)cc(C3(S(C)(=O)=O)CC3)n2)c2cc[nH]c12 CHEMBL2325721 IC50 220.0 nM
C[C@@H]1COCCN1c1nc(-n2c(N(C)C)nc3ccccc32)nc2c(S(C)(=O)=O)csc12 CHEMBL5416889 IC50 233.3 nM
CS(=O)(=O)C1(c2cc(N3C4CCC3COC4)nc(-c3cncc4[nH]ccc34)n2)CC1 CHEMBL4292532 IC50 260.0 nM
Nc1nc2c(s1)CC(n1nc(-c3cnc4[nH]ccc4c3)c3c(N)ncnc31)CC2 CHEMBL4207205 IC50 269.0 nM
COc1cccc2c1nc(N)n2-c1nc(N2CCOC[C@H]2C)cc(C2(S(C)(=O)=O)CC2)n1 CHEMBL4279950 IC50 270.0 nM
CC1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2ccc(-c3ccncc3)cc12 CHEMBL5186126 IC50 275.0 nM
COc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCNCC2)c(=O)n4C)cn1 CHEMBL3938266 IC50 281.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2ccc(-c3cccn3C)cc12 CHEMBL5203170 IC50 289.0 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]c(C#N)cc34)n2)CC1 CHEMBL2325723 IC50 300.0 nM
CC(C)Oc1cc(N2C3CCC2COC3)nc2c(-c3ccn[nH]3)nccc12 CHEMBL4641978 IC50 310.0 nM
Nc1ncc(-c2ccc(O)cc2)nc1C(=O)Nc1ccccc1 CHEMBL1766780 IC50 320.0 nM
CC(C)Oc1cc(N2CCOCC2)nc2c(-c3ccc[nH]3)nccc12 CHEMBL4644965 IC50 339.0 nM
CS(=O)(=O)c1cccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)c1 CHEMBL1766773 IC50 340.0 nM
CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3ccccc3)n2)CC1 CHEMBL2325713 IC50 360.0 nM
C[C@H]1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-c2cncc3[nH]ccc23)n1 CHEMBL4289120 IC50 360.0 nM
C[C@@H]1COCCN1c1nc(N2CCOC[C@@H]2C)nc2sc(-c3cc[nH]n3)nc12 CHEMBL4518369 IC50 390.0 nM
FC(F)c1cncc(-c2ccc3ncc4nnc(C5=CCCOCC5)n4c3c2)c1 CHEMBL4851439 IC50 394.0 nM
N#Cc1cccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)c1 CHEMBL1766772 IC50 400.0 nM
CC(C)Oc1cc(N2[C@H](C)COC[C@@H]2C)nc2c(-c3ccn[nH]3)nccc12 CHEMBL4639008 IC50 413.0 nM
Cn1c(=O)n(C2CCOCC2)c2c3cc(-c4cnn(CCCO)c4)ccc3ncc21 CHEMBL3915261 IC50 418.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2ccc(-c3ccnn3C3CCCCO3)cc12 CHEMBL5184308 IC50 435.0 nM
C[C@@H]1Cn2ncc(C3CCN(S(C)(=O)=O)CC3)c2CN1c1ccnc(N)c1 CHEMBL3355076 IC50 440.0 nM
Nc1ncc(-c2cccc(O)c2)nc1C(=O)Nc1ccccc1 CHEMBL1766774 IC50 540.0 nM
COc1ccc2c(c1)nc(N)n2-c1nc(N2CCOC[C@H]2C)cc(C2(S(C)(=O)=O)CC2)n1 CHEMBL4282440 IC50 550.0 nM
Cc1cccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)c1 CHEMBL1766777 IC50 560.0 nM
CC1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2ccc(-c3ccc(N4CCOCC4)nc3)cc12 CHEMBL5176656 IC50 578.0 nM
Cn1ccc2cc(-c3nn(C4CCc5ccccc5C4)c4ncnc(N)c34)cnc21 CHEMBL4213994 IC50 580.0 nM
CC(C)Oc1cc(N2CCOCC2)nc2c(-c3cc[nH]c3)nccc12 CHEMBL4634705 IC50 589.0 nM
Cn1nccc1-c1ccc2nc(-c3cccc4[nH]ccc34)nc(N3CC4CC3CO4)c2c1 CHEMBL5208355 IC50 609.0 nM
Nc1ncc(-c2ccccc2)nc1C(=O)Nc1ccccc1 CHEMBL1766759 IC50 620.0 nM
Nc1ncc(-c2ccncc2)nc1C(=O)Nc1ccccc1 CHEMBL1766764 IC50 640.0 nM
C[C@H](Nc1c(C(N)=O)cnc2ccc(-c3cccnc3)cc12)c1ccn(C)n1 CHEMBL4591401 IC50 640.0 nM
Nc1ncnc2c1c(-c1cnc3[nH]ccc3c1)nn2C1Cc2ccccc2C1 CHEMBL4210861 IC50 654.0 nM
Nc1ncc(-c2ccccc2Cl)nc1C(=O)Nc1ccccc1 CHEMBL1766770 IC50 700.0 nM
C[C@@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2ccc(-c3cnn(C)c3)cc12 CHEMBL5180248 IC50 700.0 nM
C[C@H]1COCCN1c1nc(-c2cccc3[nH]ccc23)nc2ccc(-c3ccnn3C)cc12 CHEMBL5203964 IC50 700.0 nM
CN(C)C(=O)c1cc(-c2nc(N3CCOCC3)cc(C3(S(C)(=O)=O)CC3)n2)c2cc[nH]c2c1 CHEMBL2325725 IC50 720.0 nM
CCC(CC)CNc1c(C(N)=O)cnc2ccc(-c3ccncc3)cc12 CHEMBL4569880 IC50 730.0 nM
CC(C)Oc1cc(N2[C@H](C)COC[C@H]2C)nc2c(-c3ccn[nH]3)nccc12 CHEMBL4637335 IC50 730.0 nM
COc1ccccc1-c1cnc(N)c(C(=O)Nc2ccccc2)n1 CHEMBL1766769 IC50 740.0 nM
CCOC(c1ccc2nc(-c3cccc4[nH]ccc34)nc(N3CCOC[C@H]3C)c2c1)n1cccn1 CHEMBL5172751 IC50 901.0 nM
CC(C)Oc1cc(N2C[C@@H]3C[C@H]2CO3)nc2c(-c3ccn[nH]3)nccc12 CHEMBL4642004 IC50 922.0 nM
CC(C)Oc1cc(N2CCOC[C@@H]2C)nc2c(-c3ccn[nH]3)nccc12 CHEMBL4643415 IC50 1000.0 nM