Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c2ccccc2c1Cl CHEMBL4551635 IC50 27.0 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(S(=O)(=O)c2ccccc2)[nH]c1=O CHEMBL5220763 IC50 60.0 nM
CCCCc1cc(=O)n2nc(NCc3c(F)cc(Cl)cc3F)c(C#N)c2[nH]1 CHEMBL3617085 pIC50 63.1 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c2ccccc2c1C#N CHEMBL5219349 IC50 70.0 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(Cl)cc1C#N CHEMBL5220953 IC50 120.0 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(C(F)(F)c2ccccc2)[nH]c1=O CHEMBL5218588 IC50 145.0 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(C(F)F)[nH]c1=O CHEMBL5220319 IC50 150.0 nM
N#Cc1cc(F)c(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)cc1Oc1ccccc1Cl CHEMBL5218805 IC50 159.0 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(C(F)(F)F)[nH]c1=O CHEMBL5220178 IC50 162.0 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(C2CC2)[nH]c1=O CHEMBL5219314 IC50 180.0 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)c3ccccc3)[nH]c2=O)c2ccccc2c1Cl CHEMBL5219436 IC50 180.0 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(Br)cc1C#N CHEMBL5220903 IC50 200.0 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(C(F)(F)Cl)[nH]c1=O CHEMBL5219261 IC50 200.0 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(Br)[nH]c1=O CHEMBL5220805 IC50 200.0 nM
O=C(NNS(=O)(=O)c1ccccc1C(F)(F)F)c1cc2cc(Cl)ccc2o1 CHEMBL1231666 IC50 230.0 nM
CCCc1cc(=O)n2nc(NCc3c(F)cc(Cl)cc3F)c(C#N)c2[nH]1 CHEMBL3617078 pIC50 251.19 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(C)cc1C#N CHEMBL5220488 IC50 287.0 nM
Cc1cccc(C)c1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(F)cc1C#N CHEMBL5219683 IC50 340.0 nM
Cc1cccc(Cl)c1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(F)cc1C#N CHEMBL5218519 IC50 400.0 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(I)cc1C#N CHEMBL5219699 IC50 413.0 nM
COc1cc(Cl)c(Oc2ccccc2C)cc1-n1c(=O)cc(C(F)(F)F)[nH]c1=O CHEMBL5220057 IC50 438.0 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)ccc1C#N CHEMBL5219137 IC50 507.0 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(F)cc1C#N CHEMBL5220817 IC50 554.0 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(S(C)(=O)=O)[nH]c1=O CHEMBL5219393 IC50 700.0 nM
CCCOc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(C(F)(F)F)[nH]c1=O CHEMBL5219459 IC50 723.0 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(-c2ccccc2)[nH]c1=O CHEMBL5220789 IC50 725.0 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(C(F)(F)C(F)(F)F)[nH]c1=O CHEMBL5219673 IC50 792.0 nM
O=C(NNS(=O)(=O)c1ccccc1C(F)(F)F)c1cc2cc(Cl)ccc2[nH]1 CHEMBL205903 IC50 800.0 nM
N#Cc1cc(F)c(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)cc1Oc1c(F)cccc1F CHEMBL5218966 IC50 800.0 nM
CNC(=O)c1ccn2c(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)c(-c3ccccn3)nc2c1 CHEMBL5220587 IC50 850.0 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(C(N)=O)[nH]c1=O CHEMBL5220979 IC50 900.0 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(OC(F)(F)F)cc1C#N CHEMBL5219169 IC50 925.0 nM
N#Cc1cc(F)c(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)cc1Oc1ccccc1 CHEMBL5219665 IC50 1000.0 nM