CCCCc1cc(=O)n2nc(NCc3c(F)cc(Br)cc3F)c(C#N)c2[nH]1 CHEMBL3617086 pIC50 10.0 nM
CCCCc1cc(=O)n2nc(N[C@H](C)c3ccc(Br)cc3F)c(C#N)c2[nH]1 CHEMBL3617084 pIC50 12.59 nM
CCCCc1cc(=O)n2nc(NCc3ccc(Br)cc3F)c(C#N)c2[nH]1 CHEMBL3617083 pIC50 12.59 nM
CCCCc1cc(=O)n2nc(NCc3c(F)cc(Cl)cc3F)c(C#N)c2[nH]1 CHEMBL3617085 pIC50 15.85 nM
CCCCc1cc(=O)n2nc(NCc3ccc(Cl)cc3F)c(C#N)c2[nH]1 CHEMBL3617082 pIC50 15.85 nM
CCCc1cc(=O)n2nc(N[C@H](C)c3ccc(Br)cc3F)c(C#N)c2[nH]1 CHEMBL3617080 pIC50 19.95 nM
CCCc1cc(=O)n2nc(NCc3ccc(Br)cc3)c(C#N)c2[nH]1 CHEMBL3617095 pIC50 25.12 nM
CCCc1cc(=O)n2nc(NCc3ccc(Br)cc3F)c(C#N)c2[nH]1 CHEMBL3617079 pIC50 25.12 nM
N#Cc1c(NCc2ccc(Cl)cc2)nn2c(=O)cc(Cc3ccoc3)[nH]c12 CHEMBL3617102 pIC50 31.62 nM
CCCCc1cc(=O)n2nc(NCc3ccc(Cl)cc3)c(C#N)c2[nH]1 CHEMBL3617098 pIC50 39.81 nM
CCCc1cc(=O)n2nc(NCc3c(F)cc(Cl)cc3F)c(C#N)c2[nH]1 CHEMBL3617078 pIC50 50.12 nM
CCCc1cc(=O)n2nc(NCc3ccc(Cl)cc3F)c(C#N)c2[nH]1 CHEMBL3617077 pIC50 50.12 nM
CNC(=O)c1ccc2c(c1)nc(-c1ccccn1)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Br)s2)C1 CHEMBL3808902 pIC50 50.12 nM
CNC(=O)c1ccc2c(c1)nc(-c1ccccc1)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Br)s2)C1 CHEMBL3809839 pIC50 50.12 nM
NC(=O)c1ccc2c(c1)nc(-c1ccccn1)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Br)s2)C1 CHEMBL3808971 pIC50 63.1 nM
CCCc1cc(=O)n2nc(NCc3ccc(Cl)cc3)c(C#N)c2[nH]1 CHEMBL3617094 pIC50 79.43 nM
CNC(=O)c1ccc2c(c1)nc(-c1cccs1)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Br)s2)C1 CHEMBL3810317 pIC50 79.43 nM
N#Cc1c(NCc2ccc(Cl)cc2)nn2c(=O)cc(Cc3ccccc3)[nH]c12 CHEMBL3617096 pIC50 100.0 nM
CNC(=O)c1ccc2c(c1)nc(-c1ccsc1)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Br)s2)C1 CHEMBL3809282 pIC50 100.0 nM
CC(C)CCc1cc(=O)n2nc(NCc3ccc(Cl)cc3)c(C#N)c2[nH]1 CHEMBL3617100 pIC50 125.89 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c2ccccc2c1Cl CHEMBL4551635 IC50 130.0 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)c3ccccc3)[nH]c2=O)c2ccccc2c1Cl CHEMBL5219436 IC50 150.0 nM
CCCc1cc(=O)n2nc(NCc3ccc(Br)cn3)c(C#N)c2[nH]1 CHEMBL3617075 pIC50 158.49 nM
CNC(=O)c1ccc2c(c1)nc(-c1ccccc1SC)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Br)s2)C1 CHEMBL3809237 pIC50 158.49 nM
COc1cc(C#N)c(Oc2ccccc2C)cc1-n1c(=O)cc(C(F)(F)F)[nH]c1=O CHEMBL5220178 IC50 162.0 nM
CCCc1cc(=O)n2nc(COc3ccc(Cl)cc3)c(C#N)c2[nH]1 CHEMBL3617105 pIC50 199.53 nM
CCCc1cc(=O)n2nc(NCc3ccc(Cl)c(C)c3)c(C#N)c2[nH]1 CHEMBL3617071 pIC50 199.53 nM
Cc1c(C(=O)Nc2nncs2)sc2nc[nH]c(=O)c12 CHEMBL3794222 pIC50 199.53 nM
CCCc1cc(=O)n2nc(OCc3ccc(Cl)cc3)c(C#N)c2[nH]1 CHEMBL3617106 pIC50 251.19 nM
CCCc1cc(=O)n2nc(NCCc3ccc(Cl)cc3)c(C#N)c2[nH]1 CHEMBL3617103 pIC50 251.19 nM
CC(C)Cc1cc(=O)n2nc(NCc3ccc(Cl)cc3)c(C#N)c2[nH]1 CHEMBL3617099 pIC50 251.19 nM
CCCc1cc(=O)n2nc(NCc3ccc(C)cc3)c(C#N)c2[nH]1 CHEMBL3617070 pIC50 251.19 nM
Cc1cc2cc(C)c(SCC(=O)O)nc2cc1C CHEMBL3794419 pIC50 251.19 nM
NC(=O)c1ccc2c(c1)nc(-c1ccccn1)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Cl)s2)C1 CHEMBL3809321 pIC50 251.19 nM
N#Cc1ccc(C(=O)N[C@H]2CCC[C@@H](n3c(-c4ccccn4)nc4cc(C(N)=O)ccc43)C2)s1 CHEMBL3809916 pIC50 251.19 nM
O=C(NC1CC1)c1ccc2c(c1)nc(-c1ccccn1)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Br)s2)C1 CHEMBL3808894 pIC50 251.19 nM
Cc1ccccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c2ccccc2c1C#N CHEMBL5219349 IC50 270.0 nM
CCCc1cc(=O)n2nc(NCc3ccc(Cl)c(F)c3)c(C#N)c2[nH]1 CHEMBL3617076 pIC50 316.23 nM
CCCc1cc(=O)n2nc(CC(=O)N3CCCC3)c(C#N)c2[nH]1 CHEMBL3617088 pIC50 501.19 nM
NC(=O)c1ccc2c(c1)nc(-c1cccnc1)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Br)s2)C1 CHEMBL3808495 pIC50 501.19 nM
CCCc1cc(=O)n2nc(CCc3ccc(Cl)cc3)c(C#N)c2[nH]1 CHEMBL3617107 pIC50 630.96 nM
CCCc1cc(=O)n2nc(NCc3ccc(Br)cc3)nc2[nH]1 CHEMBL3617092 pIC50 630.96 nM
CCCc1cc(=O)n2nc(NCc3ccc(Cl)cc3OC)c(C#N)c2[nH]1 CHEMBL3617072 pIC50 630.96 nM
CNC(=O)c1ccc2c(c1)nc(-c1csc(C)n1)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Br)s2)C1 CHEMBL3809574 pIC50 630.96 nM
CC(C)NC(=O)c1ccc2c(c1)nc(-c1ccccn1)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Br)s2)C1 CHEMBL3808975 pIC50 630.96 nM
CCCc1cc(=O)n2nc(C(=O)Nc3ccc(Cl)cc3)c(C#N)c2[nH]1 CHEMBL3617087 pIC50 794.33 nM
CNC(=O)c1ccc2c(c1)nc(-c1nccs1)n2[C@@H]1CCC[C@H](NC(=O)c2ccc(Br)s2)C1 CHEMBL3808530 pIC50 794.33 nM
CCCc1cc(=O)n2nc(NC(=O)c3ccc(Cl)cc3)c(C#N)c2[nH]1 CHEMBL3617108 pIC50 1000.0 nM
Cc1c(C(=O)Nc2ccccc2CC(=O)O)sc2nc[nH]c(=O)c12 CHEMBL3794532 pIC50 1000.0 nM
O=C(N[C@H]1CCC[C@@H](n2c(-c3ccccn3)nc3ccccc32)C1)c1ccc(Br)s1 CHEMBL3809820 pIC50 1000.0 nM