Cn1ncc2c(NC(C)(C)C)nc(NC[C@@H](N)c3ccc(F)c(F)c3)nc21 CHEMBL5436586 IC50 4.62 nM
Cn1ncc2c(NCC3CC34CC4)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5413030 IC50 6.1 nM
Cn1ncc2c(NCC3CC3(C)C)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5415042 IC50 6.1 nM
Cn1ncc2c(NC3CC4(C3)CC(F)(F)C4)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5438358 IC50 6.1 nM
Cn1ncc2c(NC3CC4(CCC4)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5436795 IC50 8.0 nM
[2H]C([2H])([2H])n1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5432793 IC50 13.9 nM
Cn1ncc2c(NC3CC(C)(C)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5404773 IC50 14.0 nM
Cn1ncc2c(NCC3CC(C(F)(F)F)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5413152 IC50 17.0 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)c(F)c3)nc(NCC3(N)CC3)nc21 CHEMBL5414651 IC50 20.67 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)nc3)nc(NCC(C)(N)c3ccccc3)nc21 CHEMBL5418361 IC50 21.7 nM
Cn1ncc2c(NC3CC4(CC4)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5395461 IC50 24.0 nM
Cn1ncc2c(NC3CC4(C3)CC(F)(F)C4)nc(NCC(N)c3ccccc3)nc21 CHEMBL5396743 IC50 25.6 nM
Cn1ncc2c(NC3CC(Cl)(Cl)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5417536 IC50 25.8 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)c3cccc(Br)c3)nc21 CHEMBL5426579 IC50 27.8 nM
Cn1ncc2c(NCC3CC34CCC4)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5437313 IC50 28.0 nM
CC(C)Nc1nc(NC[C@H](N)c2cccc(Br)c2)nc2c1cnn2C CHEMBL5409071 IC50 28.4 nM
Cn1ncc2c(Nc3ccc(Cl)cc3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5428172 IC50 28.6 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5421954 IC50 29.9 nM
Cn1ncc2c(Nc3ccc(Cl)c(Cl)c3)nc(NCC3(N)CC3)nc21 CHEMBL5412120 IC50 33.3 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)nc3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5406803 IC50 33.4 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC(C)(N)c3ccccc3)nc21 CHEMBL5424258 IC50 36.1 nM
CC(C)Oc1ccc(Nc2nc(NC[C@H](N)c3ccccc3)nc3c2cnn3C)cc1 CHEMBL5414639 IC50 38.0 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)nc3)nc(NC[C@@](C)(N)c3ccccc3)nc21 CHEMBL5394381 IC50 38.1 nM
[2H]C([2H])([2H])n1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC(N)c3ccccc3)nc21 CHEMBL5428789 IC50 38.5 nM
Cn1ncc2c(NC(C)(C)C(F)(F)F)nc(NC[C@H](N)c3cccc(Br)c3)nc21 CHEMBL5399891 IC50 38.5 nM
Cn1ncc2c(NCC3CC3(Cl)Cl)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5419599 IC50 39.0 nM
Cc1ccc(Nc2nc(NCC3(N)CC3)nc3c2cnn3C)cc1Cl CHEMBL5409304 IC50 39.8 nM
Cn1ncc2c(Nc3ccc(OC(F)F)cc3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5411060 IC50 40.8 nM
[2H]C([2H])([2H])n1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC(C)(N)c3ccccc3)nc21 CHEMBL5396303 IC50 42.8 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)c3cccc(C#N)c3)nc21 CHEMBL5437091 IC50 42.8 nM
[2H]C([2H])([2H])n1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC3(N)CCC3)nc21 CHEMBL5427210 IC50 45.0 nM
[2H]C([2H])([2H])n1ncc2c(Nc3ccc(C(F)(F)F)nc3)nc(NCC(C)(N)c3ccccc3)nc21 CHEMBL5409361 IC50 46.6 nM
[2H]C([2H])([2H])n1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC3(N)CC3)nc21 CHEMBL5425295 IC50 50.0 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC(N)c3ccccc3)nc21 CHEMBL5414798 IC50 50.12 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC3(N)CCC3)nc21 CHEMBL5396955 IC50 50.5 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)nc3)nc(NCC(N)c3ccccc3)nc21 CHEMBL5397822 IC50 50.7 nM
CC1CC(Nc2nc(NC[C@H](N)c3ccccc3)nc3c2cnn3C)C1 CHEMBL5422318 IC50 50.7 nM
C#Cc1cccc(C(N)CNc2nc(NC(C)(C)C)c3cnn(C)c3n2)c1 CHEMBL5407431 IC50 51.8 nM
Cn1ncc2c(Nc3ccc(OC(F)(F)F)cc3)nc(NCC(C)(N)c3ccccc3)nc21 CHEMBL5418972 IC50 52.1 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC(N)c3ccccc3Cl)nc21 CHEMBL5398749 IC50 55.93 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC3(N)CC3)nc21 CHEMBL5407630 IC50 56.55 nM
Cn1ncc2c(Nc3ccc(Cl)cc3)nc(NCC3(N)CC3)nc21 CHEMBL5403322 IC50 57.4 nM
Cn1ncc2c(Nc3ccc(Cl)c(F)c3)nc(NCC3(N)CC3)nc21 CHEMBL5423762 IC50 59.1 nM
COc1ccc(Nc2nc(NCC3(N)CC3)nc3c2cnn3C)cc1Cl CHEMBL5403703 IC50 60.8 nM
Cn1ncc2c(NC(C)(C)C(F)(F)F)nc(NC[C@H](N)c3cccc(C#N)c3)nc21 CHEMBL5400372 IC50 61.7 nM
Cn1ncc2c(NC3CCCC3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5406947 IC50 62.0 nM
Cc1ccc(CNc2nc(NCC(N)c3ccccc3)nc3c2cnn3C)cc1Cl CHEMBL5432964 IC50 62.55 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC(N)C3CCCCC3)nc21 CHEMBL5426909 IC50 65.4 nM
[2H]C([2H])([2H])n1ncc2c(NC(C)(C)C)nc(NC[C@@H](N)c3ccccc3F)nc21 CHEMBL5434851 IC50 69.02 nM
Cn1ncc2c(Nc3ccc(OC(F)F)cc3)nc(NCC(C)(N)c3ccccc3)nc21 CHEMBL5397652 IC50 69.4 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)c3cccc(C4CC4)c3)nc21 CHEMBL5435395 IC50 70.0 nM
CC1CC1CNc1nc(NC[C@H](N)c2ccccc2)nc2c1cnn2C CHEMBL5405603 IC50 70.4 nM
Cn1ncc2c(Nc3ccc(F)cc3)nc(NCC(N)c3ccccc3)nc21 CHEMBL5400285 IC50 71.7 nM
Cn1ncc2c(NCC3CCC3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5418948 IC50 74.0 nM
Cn1ncc2c(NC3CCC3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5424189 IC50 75.5 nM
Cn1ncc2c(NC(C)(C)C3CC3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5394966 IC50 77.5 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC3(N)CCCCC3)nc21 CHEMBL5404571 IC50 77.9 nM
Cn1ncc2c(NC3CC(C)(F)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5432858 IC50 84.3 nM
Cn1ncc2c(Nc3ccc(Cl)c(Cl)c3)nc(NCC(C)(N)c3ccccc3)nc21 CHEMBL5434249 IC50 86.6 nM
Cn1ncc2c(NCc3cccc(Br)c3)nc(NCC(N)c3ccccc3)nc21 CHEMBL5406888 IC50 87.2 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC3(N)CCCC3)nc21 CHEMBL5420967 IC50 88.0 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC(N)c3ccccn3)nc21 CHEMBL5395607 IC50 89.4 nM
Cn1ncc2c(Nc3ccc(OC(F)F)cc3)nc(NCC(N)c3ccccc3)nc21 CHEMBL5434389 IC50 89.5 nM
Cn1ncc2c(NC(C)(C)C)nc(NC[C@H](N)c3ccc(C#N)cc3)nc21 CHEMBL5409742 IC50 90.0 nM
COc1ccc(Nc2nc(NC[C@H](N)c3ccccc3)nc3c2cnn3C)cc1 CHEMBL5412279 IC50 95.8 nM
Cn1ncc2c(NCc3ccc(F)c(Cl)c3)nc(NCC(N)c3ccccc3)nc21 CHEMBL5435217 IC50 109.0 nM
Cn1ncc2c(N[C@H]3C[C@H](F)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5397264 IC50 109.0 nM
Cn1ncc2c(NC34CC(c5ccccc5)(C3)C4)nc(NCC3(N)CC3)nc21 CHEMBL5438668 IC50 111.0 nM
Cn1ncc2c(NC3CC(F)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5431373 IC50 112.0 nM
Cn1ncc2c(Nc3ccc(OC(F)(F)F)cc3)nc(NCC3(N)CCCC3)nc21 CHEMBL5417959 IC50 115.0 nM
Cn1ncc2c(Nc3ccc(OC(F)F)nc3)nc(NCC(C)(N)c3ccccc3)nc21 CHEMBL5395540 IC50 116.0 nM
Cn1ncc2c(Nc3ccc(F)c(F)c3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5407649 IC50 118.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5418593 IC50 118.0 nM
CC(C)[C@@H](C)Nc1nc(NC[C@H](N)c2ccccc2)nc2c1cnn2C CHEMBL5422726 IC50 120.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)C3CCCCC3)nc21 CHEMBL5430681 IC50 123.0 nM
Cn1ncc2c(NC3(C)CCCC3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5402784 IC50 123.0 nM
Cn1ncc2c(NC3(C)CCC3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5423041 IC50 125.0 nM
Cn1ncc2c(NC34CC(C3)C4)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5394870 IC50 128.0 nM
Cn1ncc2c(NC3CC(C#N)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5395698 IC50 129.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)c3ccc(C4CC4)cc3)nc21 CHEMBL5417681 IC50 130.0 nM
Cn1ncc2c(NCc3ccc(Br)cc3)nc(NCC(N)c3ccccc3)nc21 CHEMBL5441017 IC50 132.0 nM
[2H]C([2H])([2H])n1ncc2c(NC(C)(C)C)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5415782 IC50 133.0 nM
Cc1ccc(CNc2nc(NCC(N)c3cccnc3)nc3c2cnn3C)cc1Cl CHEMBL5414184 IC50 135.0 nM
C[C@H](Nc1nc(NC[C@H](N)c2ccccc2)nc2c1cnn2C)C(F)(F)F CHEMBL5441123 IC50 136.0 nM
Cn1ncc2c(Nc3ccc(C(F)F)cc3)nc(NCC3(N)CC3)nc21 CHEMBL5413894 IC50 138.0 nM
CN(C)c1ccc(Nc2nc(NC[C@H](N)c3ccccc3)nc3c2cnn3C)cc1 CHEMBL5416578 IC50 141.0 nM
Cn1ncc2c(Nc3ccc(OC(F)F)nc3)nc(NCC(N)c3ccccc3)nc21 CHEMBL5415625 IC50 149.0 nM
Cn1ncc2c(NCC3CCC3(F)F)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5433896 IC50 149.0 nM
Cn1ncc2c(NCC(C)(C)C)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5403028 IC50 154.1 nM
Cn1ncc2c(NCC3CCC3F)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5423784 IC50 164.0 nM
Cn1ncc2c(Nc3cnc(C(F)(F)F)nc3)nc(NCC(C)(N)c3ccccc3)nc21 CHEMBL5393830 IC50 168.0 nM
Cn1ncc2c(NC34CC(F)(C3)C4)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5404190 IC50 168.0 nM
[2H]C([2H])([2H])n1ncc2c(NC(C)(C)C)nc(NCC(N)c3ccccc3)nc21 CHEMBL5404233 IC50 169.0 nM
Cn1ncc2c(Nc3ccc(F)cc3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5399384 IC50 169.0 nM
Cn1ncc2c(NC3CC(F)(F)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5409630 IC50 172.0 nM
Cn1ncc2c(Nc3ccc(OC(F)(F)F)cc3)nc(NCC3(N)CC3)nc21 CHEMBL5401274 IC50 176.0 nM
COc1ccc(CNc2nc(NCC(N)c3ccccc3)nc3c2cnn3C)c(OC)c1 CHEMBL5419982 IC50 178.0 nM
Cn1ncc2c(Nc3cc(F)c(Cl)c(F)c3)nc(NCC3(N)CC3)nc21 CHEMBL5436348 IC50 179.0 nM
C#CCCC1(CCOc2ccc(CNc3nc(NCC4(N)CC4)nc4c3cnn4C)cc2Cl)N=N1 CHEMBL5424716 IC50 179.0 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC(N)C3CC3)nc21 CHEMBL5403119 IC50 180.0 nM
C[C@@H](Nc1nc(NC[C@H](N)c2ccccc2)nc2c1cnn2C)C1CC1 CHEMBL5406082 IC50 180.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NC[C@H](N)c3ccccc3F)nc21 CHEMBL5427212 IC50 180.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NC[C@@H](N)c3ccccc3F)nc21 CHEMBL5424457 IC50 181.0 nM
Cn1ncc2c(NC34CC(C3)C4)nc(NCC(N)c3ccccc3)nc21 CHEMBL5435051 IC50 189.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)c3ccccc3)nc21 CHEMBL5420933 IC50 196.0 nM
Cn1ncc2c(Nc3ccc(OC(F)F)cc3)nc(NCC3(N)CC3)nc21 CHEMBL5422232 IC50 201.0 nM
Cn1ncc2c(Nc3ccc(OC(F)F)cc3)nc(NCC3(N)CCC3)nc21 CHEMBL5399881 IC50 201.0 nM
Cn1ncc2c(NC34CC(C#N)(C3)C4)nc(NCC(N)c3ccccc3)nc21 CHEMBL5437493 IC50 202.0 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NC[C@@H](N)c3ccccc3)nc21 CHEMBL5434235 IC50 202.4 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)nc3)nc(NC[C@@H](N)c3ccccc3)nc21 CHEMBL5403849 IC50 209.0 nM
COc1cc(Nc2nc(NCC3(N)CC3)nc3c2cnn3C)ccc1Cl CHEMBL5425531 IC50 211.0 nM
Cc1ccc(CNc2nc(NCC(N)c3ccccn3)nc3c2cnn3C)cc1Cl CHEMBL5409794 IC50 216.6 nM
Cn1ncc2c(NC34CC(F)(C3)C4)nc(NCC(N)c3ccccc3)nc21 CHEMBL5421331 IC50 230.0 nM
Cn1ncc2c(NC(C)(C)C(F)(F)F)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5406664 IC50 240.0 nM
Cn1ncc2c(Nc3ccc(F)cc3)nc(NCC3(N)CC3)nc21 CHEMBL5412041 IC50 242.0 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC3(N)CCOC3)nc21 CHEMBL5425556 IC50 252.0 nM
Cn1ncc2c(NCC(C)(F)F)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5396744 IC50 252.0 nM
Cn1ncc2c(NC3CC3(C)C)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5398637 IC50 252.0 nM
CC(C)Nc1nc(NC[C@H](N)c2ccccc2)nc2c1cnn2C CHEMBL5394904 IC50 253.0 nM
Cn1ncc2c(Nc3cccc(Cl)c3)nc(NCC3(N)CC3)nc21 CHEMBL5395282 IC50 260.0 nM
Cn1ncc2c(Nc3ccc(F)c(Cl)c3)nc(NCC3(N)CC3)nc21 CHEMBL5409225 IC50 262.0 nM
Cn1ncc2c(NCC3CC3(F)F)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5431198 IC50 266.0 nM
Cc1nn(C)c2nc(NCC(N)c3ccccc3)nc(Nc3ccc(C(F)(F)F)cc3)c12 CHEMBL5430673 IC50 270.0 nM
Cc1ccc(CNc2nc(NCC3(N)CC3)nc3c2cnn3C)cc1Cl CHEMBL5397844 IC50 274.9 nM
Cn1ncc2c(NCC3(F)CCC3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5409455 IC50 280.0 nM
Cn1ncc2c(NCC3CC(F)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5399425 IC50 288.0 nM
Cn1ncc2c(NC3CC4(CC(O)C4)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5439599 IC50 290.0 nM
Cn1ncc2c(NC3(C)CCCCC3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5429847 IC50 292.0 nM
[2H]C([2H])([2H])n1ncc2c(NC(C)(C)C)nc(NCC(N)c3ccccc3F)nc21 CHEMBL5412644 IC50 294.0 nM
CC[C@@H](N)CNc1nc(NCc2ccc(C)c(Cl)c2)c2cnn(C)c2n1 CHEMBL5395669 IC50 298.6 nM
Cn1ncc2c(Nc3ccc(OC(F)F)cc3)nc(NCC3(N)CCCC3)nc21 CHEMBL5404421 IC50 305.0 nM
Cn1ncc2c(NCC(F)(F)F)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5430469 IC50 316.0 nM
CC(C)CNc1nc(NC[C@H](N)c2ccccc2)nc2c1cnn2C CHEMBL5425021 IC50 321.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NC[C@H](N)c3ccccc3Cl)nc21 CHEMBL5421063 IC50 321.0 nM
[2H]C([2H])([2H])n1ncc2c(NC(C)(C)C)nc(NCC(C)(N)c3ccccc3)nc21 CHEMBL5394098 IC50 325.0 nM
COc1ccc(Nc2nc(NCC3(N)CC3)nc3c2cnn3C)cc1 CHEMBL5431261 IC50 327.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NC[C@H](N)c3ccc(F)cc3)nc21 CHEMBL5420721 IC50 330.0 nM
CCC(C)(C)Nc1nc(NC[C@H](N)c2ccccc2)nc2c1cnn2C CHEMBL5435876 IC50 330.0 nM
CC(C)Oc1ccc(Nc2nc(NCC3(N)CC3)nc3c2cnn3C)cc1 CHEMBL5425830 IC50 332.0 nM
COC1CC(Nc2nc(NC[C@H](N)c3ccccc3)nc3c2cnn3C)C1 CHEMBL5422427 IC50 343.0 nM
[2H]C([2H])([2H])n1ncc2c(Nc3ccc(C(F)(F)F)nc3)nc(NCC3(N)CC3)nc21 CHEMBL5417287 IC50 344.0 nM
Cc1ccc(CNc2nc(NCC(N)c3ccccc3F)nc3c2cnn3C)cc1Cl CHEMBL5416940 IC50 345.0 nM
Cn1ncc2c(Nc3ccc(F)c(F)c3)nc(NCC3(N)CC3)nc21 CHEMBL5420909 IC50 350.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)c3ccc(F)c(F)c3)nc21 CHEMBL5405449 IC50 350.0 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)nc3)nc(NCC3(N)CCCC3)nc21 CHEMBL5416387 IC50 357.0 nM
Cn1ncc2c(NCc3ccc(Br)cc3)nc(NCC3(N)CC3)nc21 CHEMBL5437586 IC50 369.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)c3ccc(F)cc3)nc21 CHEMBL5428103 IC50 370.0 nM
Cn1ncc2c(NC3CC4(COC4)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5423902 IC50 374.0 nM
CC(C)Nc1nc(NCC(N)c2ccc(Br)cc2)nc2c1cnn2C CHEMBL5441004 IC50 375.0 nM
Cn1ncc2c(NC3(C(F)(F)F)CC3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5419873 IC50 379.0 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC3(N)COC3)nc21 CHEMBL5407271 IC50 383.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)c3ccccc3F)nc21 CHEMBL5414955 IC50 383.0 nM
Cn1ncc2c(NCC(F)F)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5419299 IC50 412.0 nM
Cn1ncc2c(NCc3ccc(F)cc3F)nc(NCC(N)c3ccccc3)nc21 CHEMBL5421751 IC50 423.9 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)nc3)nc(NCC3(N)CC3)nc21 CHEMBL5399899 IC50 424.0 nM
Cn1ncc2c(Nc3ccc(Cl)c(C#N)c3)nc(NCC3(N)CC3)nc21 CHEMBL5396958 IC50 440.0 nM
Cn1ncc2c(Nc3cccc(C(F)F)c3)nc(NCC3(N)CC3)nc21 CHEMBL5394746 IC50 443.0 nM
Cn1ncc2c(Nc3cccc(F)c3)nc(NCC3(N)CC3)nc21 CHEMBL5417994 IC50 444.0 nM
Cn1ncc2c(Nc3ccc(Cl)cc3F)nc(NCC3(N)CC3)nc21 CHEMBL5405699 IC50 446.0 nM
Cn1ncc2c(NC3CCC(C(F)(F)F)CC3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5413188 IC50 450.0 nM
Cn1ncc2c(NC3CCC(F)(F)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5435650 IC50 450.0 nM
Cn1ncc2c(Nc3cc(F)cc(Cl)c3)nc(NCC3(N)CC3)nc21 CHEMBL5429731 IC50 452.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)c3ccccc3Cl)nc21 CHEMBL5429232 IC50 462.0 nM
CNc1nc(NCC(N)c2cccc(Br)c2)nc2c1cnn2C CHEMBL5439003 IC50 470.0 nM
Cn1ncc2c(Nc3ccc(C(F)(F)F)cc3)nc(NCC3(N)CC(F)(F)C3)nc21 CHEMBL5414689 IC50 479.0 nM
Cn1ncc2c(Nc3ccccc3)nc(NCC3(N)CC3)nc21 CHEMBL5395038 IC50 490.0 nM
CC(C)Nc1nc(NCC(N)c2ccccc2)nc2c1cnn2C CHEMBL5410082 IC50 501.0 nM
Cn1ncc2c(NCc3ccc(F)c(Cl)c3)nc(NCC3(N)CC3)nc21 CHEMBL5399222 IC50 505.0 nM
Cn1ncc2c(Nc3cccc(C(F)(F)F)c3)nc(NCC3(N)CC3)nc21 CHEMBL5395570 IC50 509.0 nM
Cn1ncc2c(Nc3cccc(OC(F)F)c3)nc(NCC3(N)CC3)nc21 CHEMBL5394918 IC50 514.0 nM
Cn1ncc2c(NC3CC34CC4)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5420254 IC50 518.0 nM
Cn1ncc2c(NCC(F)(F)F)nc(NCC(N)c3ccccc3)nc21 CHEMBL5403730 IC50 527.0 nM
Cn1ncc2c(NCCC(F)(F)F)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5412028 IC50 540.0 nM
COc1ccc(-c2cccc(Nc3nc(NCCN)nc4c3cnn4C)c2)cc1 CHEMBL5398923 IC50 541.1 nM
Cc1nn(C)c2nc(NCC3(N)CC3)nc(Nc3ccc(C(F)(F)F)cc3)c12 CHEMBL5414881 IC50 545.0 nM
Cn1ncc2c(NCC(C)(C)F)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5434704 IC50 553.0 nM
CNc1nc(NCC(N)c2ccccc2)nc2c1cnn2C CHEMBL5428893 IC50 554.0 nM
COc1cccc(-c2ccc(Nc3nc(NCCN)nc4c3cnn4C)cc2)c1 CHEMBL5407789 IC50 568.1 nM
Cn1ncc2c(N[C@H]3C[C@@H](F)C3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5428386 IC50 576.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(C)(N)c3ccccc3)nc21 CHEMBL5417932 IC50 581.0 nM
Cn1ncc2c(NC3CC(CO)(CCl)C3)nc(NCC(N)c3ccccc3)nc21 CHEMBL5411438 IC50 583.0 nM
Cn1ncc2c(NCc3cccc(Br)c3)nc(NCC3(N)CC3)nc21 CHEMBL5395384 IC50 588.0 nM
COC[C@@H](C)Nc1nc(NC[C@H](N)c2ccccc2)nc2c1cnn2C CHEMBL5407148 IC50 608.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)c3ccccc3Br)nc21 CHEMBL5421709 IC50 609.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NCC(N)c3cccnc3)nc21 CHEMBL5403499 IC50 615.0 nM
Cc1ccc(CNc2nc(NC[C@@H](C)N)nc3c2cnn3C)cc1Cl CHEMBL5397441 IC50 664.5 nM
CNc1nc(NCC(N)c2cccc(C#N)c2)nc2c1cnn2C CHEMBL5409380 IC50 694.0 nM
Cn1ncc2c(Nc3cccc(-c4ccccc4)c3)nc(NCCN)nc21 CHEMBL5397898 IC50 743.6 nM
COc1ccc(CNc2nc(NCC(C)(C)N)nc3c2cnn3C)cc1Cl CHEMBL5397990 IC50 744.3 nM
COc1cccc(-c2cccc(Nc3nc(NCCN)nc4c3cnn4C)c2)c1 CHEMBL5424728 IC50 762.2 nM
Cn1ncc2c(NCc3ccc(-c4ccccc4)cc3)nc(NCC(C)(C)N)nc21 CHEMBL5419836 IC50 765.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NC[C@H](N)c3ccc(F)c(F)c3)nc21 CHEMBL5434257 IC50 800.0 nM
Cn1ncc2c(NC(C)(C)C)nc(NC[C@H](N)C3CCCCC3)nc21 CHEMBL5412192 IC50 800.0 nM
Cc1nn(C)c2nc(NCC(C)(C)N)nc(NCc3ccc(-c4ccccc4)cc3)c12 CHEMBL5427666 IC50 814.2 nM
Cn1ncc2c(NC3CCOCC3)nc(NC[C@H](N)c3ccccc3)nc21 CHEMBL5425850 IC50 851.0 nM
Cc1ccc(CNc2nc(N[C@H]3CCCC[C@H]3N)nc3c2cnn3C)cc1Cl CHEMBL5437436 IC50 898.8 nM
Cn1ncc2c(Nc3ccc(Oc4ccccc4)cc3)nc(NCCN)nc21 CHEMBL5402814 IC50 917.9 nM
CCNc1nc(NCC(N)c2ccccc2)nc2c1cnn2C CHEMBL5403148 IC50 945.0 nM
Cn1ncc2c(Nc3ccc(C#N)cc3)nc(NCC3(N)CC3)nc21 CHEMBL5402054 IC50 976.0 nM
[2H]C([2H])([2H])n1ncc2c(NC(C)(C)C)nc(NC[C@H](N)c3ccccc3F)nc21 CHEMBL5415898 IC50 981.0 nM
Cn1ncc2c(Nc3cc(F)cc(F)c3)nc(NCC3(N)CC3)nc21 CHEMBL5422458 IC50 1000.0 nM