CC1=C(CC(=O)O)c2cc(F)ccc2/C1=C\c1ccc([S+](C)[O-])cc1 CHEMBL15770 Potency 0.01995 nM
CCCCCN(CCCCC)C(=O)C(CCC(=O)[O-])NC(=O)c1ccc(Cl)c(Cl)c1 CHEMBL1255589 Potency 0.02818 nM
CN[C@@H](C)[C@H](O)c1ccccc1 CHEMBL1523964 Potency 0.02818 nM
CN1C(C)(C)CCCC1(C)C CHEMBL1256139 Potency 0.0398 nM
C[N+](C)(C)CCO CHEMBL1256479 Potency 0.04467 nM
NCC(O)(CS(=O)(=O)O)c1ccc(Cl)cc1 CHEMBL1256573 Potency 0.0501 nM
NC(=O)CN1CCCC1=O CHEMBL36715 Potency 0.0562 nM
COc1cc2c(CCNC(C)=O)c[nH]c2cc1Cl CHEMBL34730 Potency 0.0562 nM
NCCc1c[nH]cn1 CHEMBL1533310 Potency 0.07079 nM
O=C1CC[C@@]2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)[C@H]1O5 CHEMBL2373589 Potency 0.07079 nM
Cc1cccc(C#Cc2ccccc2)n1 CHEMBL1255868 Potency 0.0794 nM
O=C(O)c1ccccc1Nc1ccccc1 CHEMBL23832 Potency 0.1 nM
CCCC(CCC)C(=O)[O-] CHEMBL433 Potency 0.1 nM
NC(C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(Cl)CS[C@H]12)c1ccccc1 CHEMBL8867 Potency 0.1 nM
O=C([O-])/C=C/C(O)c1ccc(Cl)cc1 CHEMBL1329790 Potency 0.2 nM
O=c1c(-c2ccc(O)cc2)coc2cc(O)cc(O)c12 CHEMBL44 Potency 0.2 nM
CC(C)c1cc(F)cc2c1C[C@](CCN(C)CCCc1nc3ccccc3[nH]1)(OC(=O)C1CC1)CC2 CHEMBL1528565 Potency 0.2 nM
CCCN1CCC[C@H](c2cccc(O)c2)C1 CHEMBL1255841 Potency 0.2 nM
N[C@@]1(C(=O)O)CC[C@@H](C(=O)O)C1 CHEMBL34453 Potency 0.2 nM
Nc1nc(SCc2ccc([N+](=O)[O-])cc2)c2ncn([C@@H]3O[C@H](CO)[C@H](O)[C@H]3O)c2n1 CHEMBL1592139 Potency 0.3 nM
CCCCC1C(=O)N(c2ccccc2)N(c2ccccc2)C1=O CHEMBL101 Potency 0.3 nM
O=C1CCC(N2C(=O)c3ccccc3C2=O)C(=O)N1 CHEMBL468 Potency 0.3 nM
N=C(N)N[C@@H](CCC(=O)O)C(=O)O CHEMBL1256283 Potency 0.3 nM
N[C@@H](CCl)C(=O)O CHEMBL1256132 Potency 0.4 nM
Cc1cccc(C)c1OCC(N)C(C)C CHEMBL1480136 Potency 0.4 nM
FC(F)(F)c1cc(CO[C@H]2CCCN[C@H]2c2ccccc2)cc(C(F)(F)F)c1 CHEMBL1256740 Potency 0.4 nM
C[N+]1(C)CCN(c2ccccc2)CC1 CHEMBL47814 Potency 0.4 nM
CCCn1c(=O)c2nc(C3CCCC3)[nH]c2n(CCCOC(=O)c2ccc(S(=O)(=O)F)cc2)c1=O CHEMBL327708 Potency 0.4 nM
CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@H](C=O)Cc1ccccc1 CHEMBL286722 Potency 0.4 nM
CCCN(CCC)C1Cc2cc(OC)c(OC)cc2C1 CHEMBL1256838 Potency 0.4 nM
Clc1cccc(N2CCNCC2)c1 CHEMBL1256029 Potency 0.4 nM
C=CCN1CCC2(C)c3cc(O)ccc3CC1C2C CHEMBL1256959 Potency 0.4 nM
CC(C)C[C@H](N)CSSC[C@@H](N)CC(C)C CHEMBL1523894 Potency 0.4 nM
NC1CCc2cc(O)c(O)cc2C1 CHEMBL1255656 Potency 0.4 nM
CCCCCCCCCCCCCCC/C=C/[C@@H](O)[C@H](NC(=O)CCCCCCCCCCCCC)OC CHEMBL1322478 Potency 0.5 nM
CCN1CCC[C@H]1CNC(=O)c1cc(S(N)(=O)=O)ccc1OC CHEMBL267044 Potency 0.5 nM
CNCC[C@@H](Oc1ccc(C(F)(F)F)cc1)c1ccccc1 CHEMBL1256757 Potency 0.5 nM
CCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)nc(NCCc4ccc(CCC(=O)O)cc4)nc32)[C@H](O)[C@H]1O CHEMBL1605057 Potency 0.6 nM
NC1CCN(c2cccc(Cl)n2)CC1 CHEMBL1256322 Potency 0.6 nM
CCCN1CCC[C@@H](c2cccc(C#N)c2)C1 CHEMBL1255935 Potency 0.6 nM
S=C(NC1CCCCC1)N1CCC(c2cnc[nH]2)CC1 CHEMBL1256702 Potency 0.6 nM
CCCOc1ccccc1-c1nc2[nH]nnc2c(=O)[nH]1 CHEMBL28079 Potency 0.6 nM
COCCc1ccc(OCC(O)CNC(C)C)cc1 CHEMBL2062335 Potency 0.6 nM
Cc1ccccc1N1C(=O)c2cc(S(N)(=O)=O)c(Cl)cc2NC1C CHEMBL878 Potency 0.6 nM
NCCC(=O)NCCc1c[nH]cn1 CHEMBL1255583 Potency 0.7 nM
O=C(O)CCC(=O)N1CCCC1C(=O)O CHEMBL302840 Potency 0.7 nM
O=C1NCC2(CCN(CCc3ccccc3)CC2)O1 CHEMBL1256849 Potency 0.7 nM
COc1ccc(CCN)cc1O CHEMBL1526852 Potency 0.8 nM
C[N+](C)(C)CCOC(N)=O CHEMBL14 Potency 0.8 nM
Cc1cccc(C(=O)NCN2CCN(c3ccccc3C#N)CC2)c1 CHEMBL1256874 Potency 0.8 nM
CCOC(=O)[N-]c1c[n+](N2CCOCC2)no1 CHEMBL1329455 Potency 0.8 nM
NC1(C(=O)O)CCCCC1 CHEMBL1256358 Potency 0.8 nM
CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(F)ccc1-2 CHEMBL407 Potency 0.8 nM
CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 CHEMBL1256389 Potency 0.8 nM
COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccccc1 CHEMBL1256943 Potency 0.8 nM
CCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@H]1O CHEMBL1364534 Potency 0.8 nM
O=C(O)CCCc1ccc(N(CCCl)CCCl)cc1 CHEMBL515 Potency 0.8 nM
Nc1ccc(CCNc2ncnc3c2ncn3C2OC(CO)C(O)C2O)cc1 CHEMBL326958 Potency 0.8 nM
CNCCc1c[nH]c2ccc(O)cc12 CHEMBL1256286 Potency 0.9 nM
C1CCC(/N=C(\NC23CC4CC(CC(C4)C2)C3)N2CCOCC2)CC1 CHEMBL541543 Potency 0.9 nM
Oc1ccc(C2CNCc3sccc32)cc1O CHEMBL1256191 Potency 0.9 nM
CC(Cc1ccc(OCC(=O)[O-])cc1)NCC(O)c1cccc(Cl)c1 CHEMBL1445411 Potency 0.9 nM
O=C(O)Cc1c[nH]cn1 CHEMBL1256325 Potency 0.9 nM
CCN(CC)c1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)([O-])OP(=O)([O-])C(Br)(Br)P(=O)([O-])O)[C@@H](O)[C@H]1O CHEMBL1318512 Potency 0.9 nM
CNc1ncnc2c1ncn2[C@H]1C[C@H](OP(=O)(O)O)[C@@H](COP(=O)(O)O)O1 CHEMBL1096400 Potency 0.9 nM
NC(=O)CNCCC(c1ccccc1)c1ccccc1 CHEMBL1255662 Potency 1.0 nM
NNC(=O)c1ccc(O)cc1 CHEMBL124267 Potency 1.0 nM
N[C@@H](Cn1cc(I)c(=O)[nH]c1=O)C(=O)O CHEMBL121915 Potency 1.0 nM
CCN(CC)C(=O)c1ccc(O)c(OC)c1 CHEMBL1229908 Potency 1.0 nM
O=C(c1ccccc1)c1ccc2n1CCC2C(=O)O CHEMBL1201124 Potency 1.0 nM
CC(N)=O CHEMBL16081 Potency 1.1 nM
OC[C@H]1O[C@@H](n2cnc3cncnc32)[C@H](O)[C@@H]1O CHEMBL1399702 Potency 1.1 nM
Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])[C@H](O)[C@H]1O CHEMBL1608159 Potency 1.1 nM
O=C(CCCN1CCC2(CC1)C(=O)NCN2c1ccccc1)c1ccc(F)cc1 CHEMBL1256875 Potency 1.1 nM
N[C@@H]1CONC1=O CHEMBL771 Potency 1.1 nM
Cc1nc2c(OCc3ccccc3)cccn2c1CC#N CHEMBL47529 Potency 1.1 nM
CSc1ccc(C(=O)c2[nH]c(=O)[nH]c2C)cc1 CHEMBL249856 Potency 1.3 nM
CN(C)C(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL1707 Potency 1.3 nM
c1ccc2c(c1)OCC(C1=NCCN1)O2 CHEMBL543467 Potency 1.3 nM
O=[N+]([O-])c1cccc2cn[nH]c12 CHEMBL247378 Potency 1.4 nM
NC(N)=Nc1nc(CSCC/C(N)=N/S(N)(=O)=O)cs1 CHEMBL902 Potency 1.6 nM
NCCS CHEMBL1256137 Potency 1.6 nM
Nc1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1 CHEMBL1489 Potency 1.6 nM
COc1ccc2[nH]cc(CCNC(C)=O)c2c1 CHEMBL45 Potency 1.6 nM
CCN1CCCC1CNC(=O)c1cc(S(N)(=O)=O)ccc1OC CHEMBL26 Potency 1.6 nM
COc1ccc(CCN(C)CCc2ccc(OC)c(OC)c2)cc1OC CHEMBL1256839 Potency 1.6 nM
O=C1C=CC(=O)C=C1 CHEMBL8320 Potency 1.6 nM
O=C(O)c1cc([N+](=O)[O-])ccc1NCCCc1ccccc1 CHEMBL1256759 Potency 1.8 nM
COC(=O)Nc1nc2cc(C(=O)c3cccs3)ccc2[nH]1 CHEMBL9514 Potency 2.0 nM
CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)[O-])=C(CSc3nc(=O)c([O-])nn3C)CSC12)c1csc(N)n1 CHEMBL1414236 Potency 2.0 nM
CC(N)Cc1c[nH]c2ccc(O)cc12 CHEMBL1256710 Potency 2.0 nM
O=C(O)c1cc(=O)cc(C(=O)O)[nH]1 CHEMBL252909 Potency 2.2 nM
C[C@H](O)C(=O)C1=Nc2c(nc(N)[nH]c2=O)NC1 CHEMBL1255653 Potency 2.2 nM
O=C1NC(=O)C(c2ccccc2)(c2ccccc2)N1 CHEMBL16 Potency 2.2 nM
CN1CCC2(CCN3CCc4c(oc5ccccc45)C3C2)N(C)C1=O CHEMBL1405759 Potency 2.2 nM
CC[N+](C)(C)c1cccc(O)c1 CHEMBL1128 Potency 2.5 nM
N[C@H](CO)C(=O)O CHEMBL285123 Potency 2.5 nM
CC(C)[N+]1(C)C2CCC1CC(C(=O)OC(CO)c1ccccc1)C2 CHEMBL1394801 Potency 2.5 nM
CC(C)(C)c1onc(O)c1CC(N)C(=O)O CHEMBL113180 Potency 2.5 nM
Cc1cn([C@H]2C[C@@H](N=[N+]=[N-])[C@@H](CO)O2)c(=O)[nH]c1=O CHEMBL26318 Potency 2.5 nM
O=C([O-])Cc1ccccc1Nc1c(Cl)cccc1Cl CHEMBL1034 Potency 2.5 nM
CC1(C)CCC(NC(=O)[C@@H](N)CCC(=O)O)CC1 CHEMBL1255840 Potency 2.5 nM
CC(=O)OC(C)C[N+](C)(C)C CHEMBL1200764 Potency 2.5 nM
CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C CHEMBL710 Potency 2.8 nM
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C3C(C[C@H](O)C21C)C1(C)CC[C@@H](O)CC1C[C@H]3O CHEMBL1594626 Potency 2.8 nM
CC(C)Cc1ccc([C@H](C)C(=O)O)cc1 CHEMBL175 Potency 2.8 nM
NC(N)=NOCC[C@H](N)C(=O)O CHEMBL1551643 Potency 2.8 nM
CC1C(=O)N(C)C(=O)c2[nH]cnc21 CHEMBL1556654 Potency 2.8 nM
CC[C@@H]1C(=O)OC[C@@H]1Cc1cncn1C CHEMBL1200330 Potency 2.8 nM
Oc1ccc(O)cc1 CHEMBL537 Potency 2.8 nM
NCCCCC(=O)O CHEMBL1256511 Potency 2.8 nM
C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2CC[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CO CHEMBL253144 Potency 2.8 nM
CCN(CCCl)Cc1ccccc1Br CHEMBL1255650 Potency 2.8 nM
OC1CCCCC1N1CCC(c2ccccc2)CC1 CHEMBL1256846 Potency 2.8 nM
COc1c2c(nc3ccccc13)OC(C(C)(O)CO)C2 CHEMBL1255737 Potency 2.8 nM
Nc1nc2c(nc(Br)n2C2O[C@H]3CO[P@@](=O)([O-])O[C@@H]3C2O)c(=O)[nH]1 CHEMBL1436268 Potency 2.8 nM
CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])[C@H](O)[C@H]3O)c2n1 CHEMBL1590552 Potency 2.8 nM
Clc1cccc(Cl)c1NC1=NCCN1 CHEMBL1705 Potency 2.8 nM
CCCC[N+]1(C)C2CC(OC(=O)C(CO)c3ccccc3)CC1C1OC12 CHEMBL21823 Potency 2.8 nM
O=C([O-])c1cc2cc(Cc3cccnc3)ccc2o1 CHEMBL36028 Potency 2.8 nM
N[C@H]1CONC1=O CHEMBL448864 Potency 2.8 nM
N=C(N)NCCCCN CHEMBL1256618 Potency 2.8 nM
CN(C)CCOC(=O)COc1ccc(Cl)cc1 CHEMBL1256131 Potency 2.8 nM
NC(=O)c1ccccc1 CHEMBL267373 Potency 2.8 nM
CC(=O)c1ccc(S(=O)(=O)NC(=O)NC2CCCCC2)cc1 CHEMBL1589 Potency 2.8 nM
NC(=O)C(=O)[O-] CHEMBL1256289 Potency 2.8 nM
N[C@@H](Cn1oc(=O)[nH]c1=O)C(=O)O CHEMBL279956 Potency 2.8 nM
C=CCn1c(=O)c2c(nc(-c3ccc(S(=O)(=O)O)cc3)n2C)n(C)c1=O CHEMBL88584 Potency 2.8 nM
N[C@@H](Cc1ccc(O)c(I)c1)C(=O)O CHEMBL479789 Potency 2.8 nM
CC(=O)Oc1ccccc1C(=O)O CHEMBL25 Potency 2.8 nM
NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1O CHEMBL245019 Potency 2.8 nM
O=C(O)c1cc(O)c2c(Cl)cc(Cl)cc2n1 CHEMBL50267 Potency 2.8 nM
COc1ccc(C(=O)NCc2cccnc2)cc1C(=O)NCc1cccnc1 CHEMBL1257015 Potency 2.8 nM
CC(=O)SCC[N+](C)(C)C CHEMBL1256181 Potency 2.8 nM
OCc1cc(C(O)CNCCCCCCOCCCCc2ccccc2)ccc1O CHEMBL1082607 Potency 2.8 nM
C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)[C@@H]([C@@H]6COC(=O)C6)CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)[C@H](O)[C@H](O)[C@H]1O CHEMBL1255733 Potency 2.8 nM
CCN(CC)CCNC(=O)c1ccc(NC(C)=O)cc1 CHEMBL1256805 Potency 2.8 nM
CSC(=N)N CHEMBL1358112 Potency 2.8 nM
CC(C)NC[C@H](O)COc1ccc(CC(N)=O)cc1 CHEMBL343633 Potency 2.8 nM
N[C@@H](COP(=O)(O)O)C(=O)O CHEMBL284377 Potency 2.8 nM
C1CCc2nnnn2CC1 CHEMBL116943 Potency 2.8 nM
CN1CCC23CCCC[C@H]2C1Cc1ccc(O)cc13 CHEMBL1333622 Potency 2.8 nM
COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)C(C2)N(CC2CC2)CCC314 CHEMBL2373666 Potency 2.8 nM
CCSC(=N)N CHEMBL1255945 Potency 2.8 nM
NC(=O)CC[C@H](N)C(=O)O CHEMBL930 Potency 2.8 nM
CNCC(O)c1ccc(O)cc1 CHEMBL33720 Potency 2.8 nM
CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C CHEMBL1255750 Potency 2.8 nM
C#CCN(C)Cc1ccccc1 CHEMBL1200425 Potency 2.8 nM
CCC(=O)N1CCN(C(=O)c2ccccc2)CC1 CHEMBL309176 Potency 2.8 nM
CC(=O)/C(C)=N/O CHEMBL1255578 Potency 2.8 nM
CC(C)(C)NCC(O)COc1nsnc1N1CCOCC1 CHEMBL1556000 Potency 3.2 nM
CCS(=O)(=O)Nc1cccc(C(=C2CCCCC2)c2c[nH]cn2)c1 CHEMBL362863 Potency 3.2 nM
NNCc1cccc(O)c1 CHEMBL1256625 Potency 3.2 nM
O=C(O)/C(=C/c1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccccc1 CHEMBL180427 Potency 3.2 nM
CC(O)[C@@H](O)[C@H]1CNc2nc(N)[nH]c(=O)c2N1 CHEMBL1354914 Potency 3.2 nM
CC1(C)CCC=[N+]1[O-] CHEMBL79824 Potency 3.2 nM
Cc1nc(/N=N/c2ccc(C(=O)[O-])cc2)c(COP(=O)([O-])[O-])c(C=O)c1O CHEMBL1257080 Potency 3.2 nM
c1ccc2c(c1)CCCC2C1=NCCN1 CHEMBL1200413 Potency 3.2 nM
C/C(O)=C(\C#N)C(=O)Nc1cc(Br)ccc1Br CHEMBL228043 Potency 3.2 nM
Nc1nc2c(ncn2COC(CO)CO)c(=O)[nH]1 CHEMBL182 Potency 3.2 nM
O=C(O)C1=CCNCC1 CHEMBL540303 Potency 3.2 nM
O=C(C1CCCCC1)N1CC(=O)N2CCc3ccccc3C2C1 CHEMBL976 Potency 3.2 nM
COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC CHEMBL22 Potency 3.2 nM
COc1ccc(CCCOc2cc(CCn3ccnc3)ccc2OC)cc1 CHEMBL1590980 Potency 3.2 nM
CCCN1CCC[C@@H]2Cc3n[nH]cc3C[C@H]21 CHEMBL1336122 Potency 3.2 nM
CCCCc1ccc(C(=O)O)nc1 CHEMBL24510 Potency 3.2 nM
CCN(CC)CC(=O)Nc1c(C)cccc1C CHEMBL541521 Potency 3.2 nM
COc1ccc2c(c1OC)C(=O)OC2[C@H]1c2cc3c(cc2CCN1C)OCO3 CHEMBL1408680 Potency 3.2 nM
CN1CCc2cc(O)c(O)cc2C(c2ccccc2)C1 CHEMBL1256698 Potency 3.2 nM
COc1cc(=O)n(C)c2c(OCC(O)C(C)(C)O)cccc12 CHEMBL1450334 Potency 3.2 nM
CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(Cl)cc(Cl)cn12 CHEMBL432608 Potency 3.2 nM
CC(=O)NCCc1c[nH]c2ccc(O)cc12 CHEMBL33103 Potency 3.2 nM
CC(=N)NCCCC[C@@H](N)C(=O)O CHEMBL1600325 Potency 3.2 nM
CCOC(=O)C12CC1/C(=N/O)c1ccccc1O2 CHEMBL388054 Potency 3.2 nM
OCCN1CCN(CCCN2c3ccccc3C=Cc3ccccc32)CC1 CHEMBL1524185 Potency 3.2 nM
COc1ccc2[nH]cc(CCN)c2c1 CHEMBL1256138 Potency 3.2 nM
CC(C)C[C@H](NC(=O)[C@H](O)[C@H](N)Cc1ccccc1)C(=O)O CHEMBL1257100 Potency 3.2 nM
OC(CCN1CCCCC1)(c1ccccc1)C1CCCCC1 CHEMBL1092 Potency 3.2 nM
CCN1/C(=C/C(C)=O)Sc2ccc(OC)cc21 CHEMBL408982 Potency 3.2 nM
NCCS(=O)O CHEMBL1256480 Potency 3.2 nM
O=C1O/C(=C/Br)CCC1c1cccc2ccccc12 CHEMBL6206 Potency 3.2 nM
CCCN1CCC[C@@H]2Cc3n[nH]cc3C[C@H]21 CHEMBL1256574 Potency 3.5 nM
CN1CCN(C2=Nc3cc(Cl)ccc3Nc3ccccc32)CC1 CHEMBL42 Potency 3.5 nM
COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 CHEMBL1256924 Potency 3.5 nM
OC(CN1CCC(Cc2ccc(F)cc2)CC1)c1ccc(Cl)cc1 CHEMBL28564 Potency 3.5 nM
N=C(N)NN CHEMBL1256292 Potency 3.5 nM
S=C(Nc1ccccc1)Nc1nccs1 CHEMBL1256364 Potency 3.5 nM
Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1O CHEMBL316966 Potency 3.5 nM
Cc1cc(C(C)(C)C)cc(C)c1CC1=NCCN1 CHEMBL1256400 Potency 3.5 nM
CCN(Cc1ccncc1)C(=O)C(CO)c1ccccc1 CHEMBL1200604 Potency 3.5 nM
O=C(O)[C@@H]1C[C@@H](C(=O)O)N1 CHEMBL43528 Potency 3.5 nM
Cc1cc(C(C)(C)C)c(O)c(C)c1CC1=NCCN1 CHEMBL1200791 Potency 3.5 nM
NCCCC(=O)O CHEMBL96 Potency 3.5 nM
COc1ccc(C(=O)N2CCCC2=O)cc1 CHEMBL36994 Potency 4.0 nM
Cc1ccc(Cl)c(Nc2ccccc2C(=O)[O-])c1Cl CHEMBL876 Potency 4.0 nM
NC(Cc1ccc(Cl)cc1)C(=O)O CHEMBL1256351 Potency 4.0 nM
CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 CHEMBL1256844 Potency 4.0 nM
CC1OC1P(=O)([O-])[O-] CHEMBL1520976 Potency 4.5 nM
CC(=O)NCCc1c[nH]c2ccccc12 CHEMBL33171 Potency 4.5 nM
C[C@]12C=CC(=O)C=C1CC[C@H]1[C@@H]3C[C@@H](O)[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@]12F CHEMBL1451 Potency 4.5 nM
CNC(=O)[C@H]1O[C@@H](n2cnc3c(NCc4ccc(N)cc4)ncnc32)[C@H](O)[C@H]1O CHEMBL1395737 Potency 5.0 nM
NC(CCCCCP(=O)(O)O)C(=O)O CHEMBL274440 Potency 5.0 nM
CCCCS(=N)(=O)CC[C@H](N)C(=O)O CHEMBL261642 Potency 5.0 nM
Brc1c(NC2=NCCN2)ccc2nccnc12 CHEMBL844 Potency 5.6 nM
CCCCN1[C@@H]2CC[C@H]1C[C@@H](OC(c1ccc(F)cc1)c1ccc(F)cc1)C2 CHEMBL3216928 Potency 5.6 nM
N#CC(=C(\N)Sc1ccccc1N)/C(C#N)=C(/N)Sc1ccccc1N CHEMBL95758 Potency 5.6 nM
CC(C)(C)c1ccc(S(=O)(=O)/C=C/C#N)cc1 CHEMBL270299 Potency 5.6 nM
Oc1cc2c(cc1O)[C@H]1c3ccccc3CN[C@@H]1CC2 CHEMBL1256832 Potency 5.6 nM
CC1(C)C(=O)N(CCN2CCC(C(=O)c3ccc(F)cc3)CC2)c2ccccc21 CHEMBL1256663 Potency 6.3 nM
Nc1cc(=O)nc(N)[nH]1 CHEMBL1255934 Potency 6.3 nM
CC(CN1c2ccccc2Sc2ccccc21)N(C)C CHEMBL1200750 Potency 6.3 nM
CCn1cc(C(=O)[O-])c(=O)c2ccc(C)nc21 CHEMBL1255939 Potency 7.1 nM
COc1cc2c(cc1O)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12 CHEMBL299613 Potency 7.1 nM
COc1cc(-c2ccc(=O)[nH]n2)ccc1OC(F)F CHEMBL313842 Potency 7.1 nM
O=C(O)/C=C/c1c[nH]cn1 CHEMBL1236602 Potency 7.9 nM
C[C@@H]1C(=O)NC2=Nc3cccc(Cl)c3CN21 CHEMBL320341 Potency 7.9 nM
CC(C)NCC(O)c1ccc(O)c(O)c1 CHEMBL1711 Potency 7.9 nM
CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O CHEMBL527 Potency 8.9 nM
OC[C@H]1O[C@@H](n2cnc3c(N[C@H]4CC5CCC4C5)ncnc32)[C@H](O)[C@@H]1O CHEMBL1394945 Potency 8.9 nM
Cc1cccc(C)c1NC1=NCCCS1 CHEMBL1256022 Potency 8.9 nM
CC(C)(C(=O)O)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1 CHEMBL914 Potency 8.9 nM
CCN(CC)CCNC(=O)c1cc(S(C)(=O)=O)ccc1OC CHEMBL1256772 Potency 10.0 nM
Nc1nc(Nc2ccccc2)nc2c1ncn2[C@@H]1O[C@H](CO)[C@H](O)[C@H]1O CHEMBL1436882 Potency 10.0 nM
Cc1ccccc1N1C(=O)c2cc([S+]([O-])ON)c(Cl)cc2NC1C CHEMBL1451377 Potency 10.0 nM
NC12CC3CC(CC(C3)C1)C2 CHEMBL1569 Potency 11.2 nM
Oc1cc(-c2ccccc2)nc2nc(Cl)ccc12 CHEMBL97760 Potency 11.2 nM
C=CC1(C)CC(=O)C2(O)C(C)(O1)C(OC(C)=O)C(O)C1C(C)(C)CCC(O)C12C CHEMBL1358402 Potency 11.2 nM
O=C(O)[C@@H]1C[C@H](C(=O)O)N1 CHEMBL41680 Potency 12.6 nM
COc1ccccc1N1CCN(CCCNc2cc(=O)n(C)c(=O)n2C)CC1 CHEMBL1256716 Potency 12.6 nM
O=[N+]([O-])c1cccc2c(Br)n[nH]c12 CHEMBL479014 Potency 12.6 nM
O=[N+]([O-])c1ccc(CSc2ncnc3c2ncn3[C@@H]2O[C@H](CO)[C@H](O)[C@H]2O)cc1 CHEMBL1475917 Potency 12.6 nM
NCCS(=O)(=O)O CHEMBL239243 Potency 12.6 nM
CC(=O)Oc1cc(C(C)C)c(OCCN(C)C)cc1C CHEMBL1256739 Potency 12.6 nM
O=NN(CCCl)C(=O)NCCCl CHEMBL513 Potency 14.1 nM
CP(=O)(O)C1=CCNCC1 CHEMBL397209 Potency 14.1 nM
c1ccc(-c2ccccn2)nc1 CHEMBL39879 Potency 14.1 nM
CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC CHEMBL107514 Potency 15.8 nM
N[C@@H](CCCC(=O)O)C(=O)O CHEMBL88804 Potency 15.8 nM
Nc1nc(OCc2ccccc2)c2nc[nH]c2n1 CHEMBL407874 Potency 15.8 nM
CCn1c(=O)[nH]c2cc(Cl)c(Cl)cc21 CHEMBL1255655 Potency 15.8 nM
c1ccc([C@H]2CN3CCSC3=N2)cc1 CHEMBL1770 Potency 15.8 nM
C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C CHEMBL983 Potency 15.8 nM
S=C([S-])OC1CC2CC1C1CCCC21 CHEMBL404954 Potency 17.8 nM
O=C(O)c1cc(O)c2ccc(Cl)cc2n1 CHEMBL311389 Potency 17.8 nM
N[C@@H](CCC(=O)N[C@H](CSN=O)C(=O)NCC(=O)O)C(=O)O CHEMBL1527722 Potency 20.0 nM
NNCCc1ccccc1 CHEMBL1200895 Potency 20.0 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O CHEMBL135 Potency 22.4 nM
Cc1[nH]c(=O)c(C#N)cc1-c1ccncc1 CHEMBL189 Potency 22.4 nM
COc1ccc2c(c1)c(CC(=O)O)c(C)n2Cc1ccc(F)cc1 CHEMBL1257014 Potency 22.4 nM
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C(=O)O)C(C)(C)CCC1 CHEMBL38 Potency 22.4 nM
CO[C@@]1(NC(=O)CSCC#N)C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CS[C@@H]21 CHEMBL1201118 Potency 22.4 nM
Clc1ccc(C(c2ccccc2Cl)C(Cl)Cl)cc1 CHEMBL1670 Potency 22.4 nM
Brc1ccc([C@H]2CN3CCSC3=N2)cc1 CHEMBL1256792 Potency 25.1 nM
NC(=S)c1ccc[n+]([C@@H]2O[C@@H](COP(=O)([O-])OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](OP(=O)([O-])O)[C@H]3O)C(O)C2O)c1 CHEMBL1596388 Potency 25.1 nM
O=C1CCCN1CC#CCN1CCCC1 CHEMBL1551988 Potency 25.1 nM
C/N=c1/nc(-c2ccccc2)n(-c2ccccc2)s1 CHEMBL536950 Potency 25.1 nM
CC(C)C(=O)c1c(C(C)C)nn2ccccc12 CHEMBL19449 Potency 25.1 nM
C[N+]1(C)CCC(OC(=O)C(c2ccccc2)c2ccccc2)CC1 CHEMBL76897 Potency 25.1 nM
COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OC CHEMBL7917 Potency 28.2 nM
N[C@H](C(=O)O)[C@H](O)C(=O)O CHEMBL1231330 Potency 28.2 nM
O=C(O)C1=CCCN(CCON=C(c2ccccc2)c2ccccc2)C1 CHEMBL545050 Potency 28.2 nM
CN1CCN(C2=Nc3ccccc3Oc3ccc(Cl)cc32)CC1 CHEMBL1201155 Potency 28.2 nM
Oc1ccc(Cn2cc[nH]c2=S)cc1 CHEMBL164747 Potency 28.2 nM
CCCN1C[C@H](CSC)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21 CHEMBL1275 Potency 31.6 nM
Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)C CHEMBL484928 Potency 35.5 nM
O=c1ccn([C@@H]2O[C@H](COP(=O)([O-])OP(=O)([O-])O)[C@@H](O)[C@H]2O)c(=O)[nH]1 CHEMBL1457622 Potency 35.5 nM
Cc1ccc(/C(=C\CN2CCCC2)c2ccccn2)cc1 CHEMBL1200450 Potency 39.8 nM
CC12C(=O)OC(=O)C1(C)C1CCC2O1 CHEMBL8066 Potency 44.7 nM
O=C(O)C1=CCCNC1 CHEMBL1256362 Potency 50.1 nM
CCN(CC)CCNC(=O)c1ccc(N)cc1 CHEMBL605 Potency 50.1 nM
O=c1cc(N2CCOCC2)oc2c(-c3ccccc3)cccc12 CHEMBL1398499 Potency 50.1 nM
C=CCN1CCC23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(O)C1C5 CHEMBL2373638 Potency 56.2 nM
NC(=O)c1cc(N2CC2)c([N+](=O)[O-])cc1[N+](=O)[O-] CHEMBL23330 Potency 56.2 nM
Cc1ccccc1CNc1ncnc2c1ncn2C1OC(CO)C(O)C1O CHEMBL18238 Potency 70.8 nM
Cc1ccc(=O)n(-c2ccccc2)c1 CHEMBL1256391 Potency 70.8 nM
O[Si](CCCN1CCCCC1)(c1ccc(F)cc1)C1CCCCC1 CHEMBL1256647 Potency 70.8 nM
CN(C)CCOC(C)(c1ccccc1)c1ccccn1 CHEMBL1200392 Potency 70.8 nM
COc1ccccc1N1CCN(CCN(C(=O)c2ccc(F)cc2)c2ccccn2)CC1 CHEMBL1355634 Potency 70.8 nM
CC(C)(C)c1onc(OCP(=O)(O)O)c1CC(N)C(=O)O CHEMBL265301 Potency 79.4 nM
Cc1ccc(C(=O)OC(C(=O)O)C(OC(=O)c2ccc(C)cc2)C(=O)O)cc1 CHEMBL2448607 Potency 79.4 nM
C[C@@]1(C2CCCC2)Cc2cc(OCC(=O)O)c(Cl)c(Cl)c2C1=O CHEMBL1406302 Potency 79.4 nM
CC(C)CC(NC(=O)c1cccc(Cl)c1)C(=O)O CHEMBL1348798 Potency 79.4 nM
OCC1O[C@H](O)C(Cl)C(O)C1O CHEMBL1369461 Potency 89.1 nM
CCN(CC)CCOC(=O)c1ccc(N)cc1 CHEMBL1200841 Potency 89.1 nM
N=C(N)c1ccccc1 CHEMBL537204 Potency 89.1 nM
CCCCCCCCCCCCCCSCC(=O)O CHEMBL187734 Potency 89.1 nM
C[Se]C[C@H](N)C(=O)O CHEMBL1256174 Potency 100.0 nM
Cc1ccccc1N1CCN(S(=O)(=O)C[C@]23CCC(CC2NC(=O)[C@@H](N)CCS(C)(=O)=O)C3(C)C)CC1 CHEMBL1450525 Potency 100.0 nM
O=C1CCc2cc(OCCCCc3nnnn3C3CCCCC3)ccc2N1 CHEMBL799 Potency 100.0 nM
C[C@H]1CC2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO CHEMBL1435313 Potency 100.0 nM
C[N+](C)(C)CC=O CHEMBL1256576 Potency 100.0 nM
CN1[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(O)c1ccccc1)C2 CHEMBL1319362 Potency 100.0 nM
O=c1oc(Cl)c(Cl)c2ccccc12 CHEMBL24983 Potency 100.0 nM
C[N+]1(C)[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2 CHEMBL2146143 Potency 100.0 nM
O=C(O)C[C@@H]1C(=O)O[C@@H]2C(COC(=O)c3cc(O)c(O)c(O)c3)O[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@@H](OC(=O)c3cc(O)c(O)c4c3[C@H]1[C@H](O)C(=O)O4)[C@H]2OC(=O)c1cc(O)c(O)c(O)c1 CHEMBL1391063 Potency 100.0 nM
N#Cc1cc(NC(=O)Nc2nnc(-c3ccncc3)s2)ccc1Cl CHEMBL2426190 IC50 100.0 nM
N#Cc1cc(NC(=O)Nc2nnc(-c3ccncc3)s2)ccc1Br CHEMBL2426164 IC50 110.0 nM
CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)C(N)c3ccccc3)[C@H]2SC1 CHEMBL6634 Potency 112.2 nM
Nc1ncnc2c1nc(Sc1ccc(Cl)cc1)n2[C@H]1O[C@@H]2CO[P@@](=O)([O-])O[C@H]2[C@@H]1O CHEMBL1455369 Potency 112.2 nM
COc1ccc(Cc2nc3ccccc3n2CC(=O)N/N=C/c2ccc(C)cc2O)cc1OC CHEMBL3191034 Potency 114.9 nM
Cc1nnc2cc(-c3ccc(C(F)(F)F)cc3)cnn12 CHEMBL1323714 Potency 125.9 nM
C=C(C)[C@H]1CN[C@H](C(=O)O)[C@H]1CC(=O)O CHEMBL275040 Potency 125.9 nM
Clc1cc(I)cc(Cl)c1N=C1NCCN1 CHEMBL1255758 Potency 125.9 nM
C=CCN1C[C@@H](C)N([C@H](c2ccc(C(=O)N(CC)CC)cc2)c2cccc(OC)c2)C[C@@H]1C CHEMBL67378 Potency 125.9 nM
CC12NC(Cc3ccccc31)c1ccccc12 CHEMBL1559482 Potency 141.3 nM
CO[C@H]1CC=C2CCN3CCC4=C(CC(=O)OC4)[C@]23C1 CHEMBL1319741 Potency 141.3 nM
CP(=O)(O)CCCN CHEMBL1256147 Potency 158.5 nM
CCOc1ccc(CCNC(=O)c2nc(-c3cccc(F)c3)n3c2CCCCC3)cc1OCC CHEMBL1394733 Potency 158.5 nM
CC1CCN=C(N)S1 CHEMBL1255839 Potency 177.8 nM
C=C(C)[C@@H]1C2OC(=O)C1[C@]1(O)C[C@H]3O[C@]34C(=O)O[C@H]2[C@]14C CHEMBL2374062 Potency 177.8 nM
N[C@@H](Cc1cnc[nH]1)C(=O)O CHEMBL1256578 Potency 199.5 nM
Cn1cnc([N+](=O)[O-])c1Sc1ncnc2[nH]cnc12 CHEMBL1542 Potency 199.5 nM
CCCn1c(=O)c2c(ncn2C)n(CCC)c1=O CHEMBL278332 Potency 199.5 nM
NCC(CC(=O)O)c1ccc(Cl)cc1 CHEMBL701 Potency 199.5 nM
CCCn1c(=O)[nH]c(=O)c2nc[nH]c21 CHEMBL279898 Potency 199.5 nM
COc1ccc(OC)c(C(O)C(C)N)c1 CHEMBL1201103 Potency 199.5 nM
C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CCC2=O CHEMBL1405 Potency 199.5 nM
CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)O)OCC3 CHEMBL622 Potency 223.9 nM
CCCN(CCC)C1CCc2cccc(O)c2C1 CHEMBL505765 Potency 223.9 nM
COc1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O)cc1 CHEMBL1697 Potency 251.2 nM
CCNC(=O)N1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL1257106 Potency 251.2 nM
CC(C)(C)NCC(O)c1ccccc1Cl CHEMBL1256478 Potency 281.8 nM
Clc1ccc(Cn2c(CN3CCCC3)nc3ccccc32)cc1 CHEMBL3216363 Potency 281.8 nM
CN1CCCC1CCOC(C)(c1ccccc1)c1ccc(Cl)cc1 CHEMBL1408519 Potency 281.8 nM
CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)C(N)C3=CCC=CC3)[C@H]2SC1 CHEMBL1489127 Potency 281.8 nM
CCn1nc(C(=O)O)c(=O)c2cc3c(cc21)OCO3 CHEMBL1208 Potency 281.8 nM
Cn1c(=O)c2nc(-c3ccccc3)[nH]c2n(C)c1=O CHEMBL62350 Potency 281.8 nM
CNC(=O)Oc1ccc2c(c1)[C@]1(C)CCN(C)[C@@H]1N2C CHEMBL94 Potency 281.8 nM
COCCCC/C(=N\OCCN)c1ccc(C(F)(F)F)cc1 CHEMBL1409 Potency 281.8 nM
COc1ccc(CCN(C)Cc2ccc(OCc3ccccc3)c(OC)c2)cc1OC CHEMBL1550052 Potency 281.8 nM
N#Cc1cc(NC(=O)Nc2nnc(-c3ccncc3)s2)ccc1F CHEMBL2426169 IC50 300.0 nM
CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 CHEMBL786 Potency 316.2 nM
CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)C4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1 CHEMBL1434334 Potency 316.2 nM
Oc1cc2c(cc1O)C(c1ccccc1)CNCC2 CHEMBL542700 Potency 316.2 nM
C=C/C(C)=C/[C@@]1(C)SC(=O)C(C)=C1O CHEMBL399043 Potency 316.2 nM
CNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@H]1O CHEMBL1442153 Potency 316.2 nM
NCC1OC(O[C@@H]2[C@H](O)[C@@H](OC3C(O)C(N)CC(N)C3OC3OC(CO)C(O)C(O)C3N)O[C@@H]2CO)C(N)C(O)C1O CHEMBL1554479 Potency 316.2 nM
CC(C)(C)NCC(O)c1cc(O)cc(O)c1 CHEMBL1315867 Potency 316.2 nM
CC(N)(C(=O)O)c1ccc(C(=O)O)cc1 CHEMBL299683 Potency 354.8 nM
NCCc1ccc(O)cc1 CHEMBL1255790 Potency 354.8 nM
C[C@]12C=CC(=O)C=C1CC[C@@H]1C2=CC[C@]2(C)[C@@H](C(=O)CN3CCN(c4cc(N5CCCC5)nc(N5CCCC5)n4)CC3)CC[C@@H]12 CHEMBL1256186 Potency 354.8 nM
CNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@H](O)[C@H]1O CHEMBL1554131 Potency 354.8 nM
CNC(=N)NCCCC(N)C(=O)O CHEMBL1331957 Potency 354.8 nM
Oc1ncnc2[nH]ncc12 CHEMBL1467 Potency 398.1 nM
Nc1ncnc2c1ncn2C1CCCO1 CHEMBL64239 Potency 398.1 nM
O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CCN(CC(=O)O)CC(=O)O CHEMBL780 Potency 446.7 nM
CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1)c1ccccn1 CHEMBL434063 Potency 446.7 nM
COc1ccccc1NC(=O)Nc1nc(-c2cccnc2)nc2ccccc12 CHEMBL70880 Potency 501.2 nM
O=c1c(-c2ccc(O)cc2)coc2cc(O)ccc12 CHEMBL8145 Potency 501.2 nM
Nc1nc2c(ncn2COCCO)c(=O)[nH]1 CHEMBL184 Potency 501.2 nM
O=C(OCC1O[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H](OC(=O)c2cc(O)c(O)c(O)c2)[C@@H]1OC(=O)c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 CHEMBL1500249 Potency 501.2 nM
O=C(NCCNCC(O)COc1ccc(O)cc1)N1CCOCC1 CHEMBL1329567 Potency 562.3 nM
NC(CP(=O)(O)O)C(=O)O CHEMBL88621 Potency 562.3 nM
COc1ccc2c(c1OC)C(=O)OC2[C@@H]1c2c(cc3c(c2OC)OCO3)CCN1C CHEMBL1531754 Potency 562.3 nM
Oc1noc2c1CCNC2 CHEMBL1255746 Potency 562.3 nM
COc1cc(C(O)CN)ccc1O CHEMBL1520394 Potency 562.3 nM
CC(C)N(CCC(C(N)=O)(c1ccccc1)c1ccccn1)C(C)C CHEMBL517 Potency 562.3 nM
NCCCP(=O)(O)O CHEMBL286077 Potency 562.3 nM
O=C(O)CC[N+](=O)[O-] CHEMBL451226 Potency 631.0 nM
NC1(C(=O)O)CCc2cc(C(=O)O)ccc21 CHEMBL313938 Potency 631.0 nM
Cn1c(=O)[nH]c2ncn(C)c2c1=O CHEMBL1158 Potency 631.0 nM
NC(=O)CI CHEMBL276727 Potency 631.0 nM
O=C(Nc1ccc(N2CCOCC2)cc1)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 CHEMBL1565212 Potency 631.0 nM
O=C(COC(=O)c1cccnc1)Nc1cccc2ccccc12 CHEMBL1447101 Potency 707.9 nM
O=C1OCC2OC(O)C(O)C(O)C2OC(=O)c2cc(O)c(O)c(O)c2-c2c(O)c(O)c3oc(=O)c4c(c(O)c(O)c5oc(=O)c2c3c54)-c2c1cc(O)c(O)c2O CHEMBL416615 Potency 707.9 nM
CCn1c(SCC(N)=O)nc2sc3c(c2c1=O)CCN(C)C3 CHEMBL1605563 Potency 707.9 nM
COCc1ccc(C(=O)N(C)CC2CCCN(CCc3ccccc3F)C2)o1 CHEMBL1582667 Potency 707.9 nM
O=S(=O)(NC(=NCc1ccccc1)c1ccccc1)c1ccc(Br)cc1 CHEMBL1490049 Potency 707.9 nM
O=c1cc2oc3cc(O)c(O)cc3c(-c3ccccc3[N+](=O)[O-])c-2cc1O CHEMBL1563898 Potency 707.9 nM
CCOCCOC(=O)c1ccc(NC(=O)C2COc3ccccc3O2)cc1 CHEMBL1470375 Potency 707.9 nM
CCN(CC)CCCNc1cc2nc(/C=C/c3ccc(C(C)C)cc3)n(CCCl)c(=O)c2cc1F CHEMBL4633662 Kd 760.0 nM
O=C(O)C1=CC(=C(c2ccc(O)c(C(=O)O)c2)c2ccc(O)c(C(=O)O)c2)C=CC1=O CHEMBL275938 Potency 794.3 nM
CCOC(=O)C1=C[C@]2(CC)CCCN3CCc4c(n1c1ccccc41)[C@@H]32 CHEMBL71752 Potency 794.3 nM
Cc1cn([C@H]2C=C[C@@H](CO)O2)c(=O)[nH]c1=O CHEMBL991 Potency 794.3 nM
COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC CHEMBL98123 Potency 794.3 nM
C/C(=C\c1ccco1)C1Nc2cccc3cccc(c23)N1 CHEMBL1576658 Potency 794.3 nM
Oc1c(Br)cc(/C=N/n2c(S)nnc2-c2ccccc2)c(Br)c1O CHEMBL3191015 Potency 794.3 nM
Cc1nn(Cc2ccccc2)c(Cl)c1/C=C/C(=O)OCC(=O)N1CCCC1=O CHEMBL1568730 Potency 794.3 nM
Cc1nc2c(=O)n(C)c(=O)nc-2n(C)n1 CHEMBL601757 Potency 794.3 nM
Cc1nn(Cc2ccccc2)c2sc(C(=O)NCc3cccnc3)cc12 CHEMBL1582759 Potency 794.3 nM
CCN(CC)CCCNc1cc2nc(/C=C/c3ccc(C(C)C)cc3)n(Cc3ccc(Br)cc3)c(=O)c2cc1F CHEMBL5423610 IC50 800.0 nM
C=CCN1CCc2cc(O)c(O)cc2C(c2ccccc2)C1 CHEMBL1256885 Potency 891.3 nM
c1ccc(CN2CCC3(CCCc4ccccc43)CC2)cc1 CHEMBL1256916 Potency 891.3 nM
CN(C)S(=O)(=O)c1ccc2c(c1)/C(=C/c1cc3c([nH]1)CCCC3)C(=O)N2 CHEMBL605003 Potency 891.3 nM
CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1 CHEMBL1700 Potency 891.3 nM
CN1CCC[C@H]1c1cccnc1 CHEMBL151515 Potency 891.3 nM
Cc1nc2c([nH]1)c(=O)n(C)c(=O)n2Cc1ccco1 CHEMBL405845 Potency 891.3 nM
CCCCCCCCCC[Si](C)(C)CCC(=O)NC(Cc1ccc(C)cc1)c1ccccc1 CHEMBL40998 Potency 891.3 nM
Cc1ccccc1N1C(=O)/C(=C/c2ccco2)C(=O)NC1=S CHEMBL1455226 Potency 891.3 nM
Cc1ccc(NC(=O)CN2C(=O)S/C(=C\c3ccc(-c4cccc(C(=O)O)c4C)o3)C2=O)cc1C CHEMBL1535723 Potency 891.3 nM
N#Cc1ccc(NC(=O)Nc2nnc(-c3ccncc3)s2)cc1Br CHEMBL2426165 IC50 910.0 nM
CCN(CC)CCCNc1cc2nc3n(c(=O)c2cc1F)CC/C3=C\c1ccc(C(C)C)cc1 CHEMBL4075790 IC50 950.0 nM