Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O CHEMBL4872300 Kd 6.3 nM
Cn1ncc(Nc2ccc(CCN)cc2)c(Br)c1=O CHEMBL4861491 Kd 9.3 nM
CC1=C(Nc2ccc(S(=O)(=O)N3CCN(C)CC3)cc2F)NC2C=CC(c3cnn(C4CC4)c3)=CN2C1=O CHEMBL4873093 IC50 16.0 nM
CCCNc1cc(-c2ccc3c(ccn3CCCN(C)C)c2)nc(S(C)(=O)=O)n1 CHEMBL4860578 IC50 16.0 nM
Cc1c(Nc2ccc(S(=O)(=O)N3CCN(C)CC3)cc2F)nc2ccc(-c3cnn(C4CC4)c3)cn2c1=O CHEMBL4780673 IC50 16.0 nM
CN(C)CCCn1ccc2cc(-c3nc(S(C)(=O)=O)nc4[nH]ccc34)ccc21 CHEMBL4873042 IC50 26.9 nM
CCNc1cc(-c2ccc3c(ccn3CCCN(C)C)c2)nc(S(C)(=O)=O)n1 CHEMBL4870170 IC50 28.8 nM
CNc1cc(-c2ccc3c(ccn3CCCN(C)C)c2)nc(S(C)(=O)=O)n1 CHEMBL4867072 IC50 32.7 nM
CNc1cc(-c2ccc3c(ccn3CCN(C)C)c2)nc(S(C)(=O)=O)n1 CHEMBL4868713 IC50 36.9 nM
CN(C)CCCc1ccc(Nc2cnn(C)c(=O)c2Cl)cc1 CHEMBL4848701 IC50 56.0 nM
COc1cc(-c2cn(C)c(=O)c(C)c2C)ccc1C1(N2CCN(C)CC2)CC1 CHEMBL5209881 IC50 58.0 nM
CCCNc1cc(-c2ccc3c(c2)c(C)cn3CCCN(C)C)nc(S(C)(=O)=O)n1 CHEMBL4866637 IC50 58.6 nM
CNc1cc(-c2ccc3c(ccn3CCCN(C)C)c2)nc([S+](C)[O-])n1 CHEMBL4851594 IC50 59.3 nM
CCCNc1cc(-c2cc(OC)c3c(ccn3CCCN(C)C)c2)nc(S(C)(=O)=O)n1 CHEMBL4862619 IC50 63.8 nM
CCCCNc1cc(-c2ccc3c(ccn3CCCN(C)C)c2)nc(S(C)(=O)=O)n1 CHEMBL4852588 IC50 113.8 nM
CN(C)CCCOc1ccc(-c2cc(NCCCn3cccn3)nc(S(C)(=O)=O)n2)cc1 CHEMBL4461619 Kd 120.0 nM
CN1C[C@H](Nc2cnn(C)c(=O)c2Br)C[C@H](c2ccccc2)C1 CHEMBL4069412 Ki 130.0 nM
CCCNc1cc(-c2ccc3c(ccn3CCCN(C)C)c2)nc([S+](C)[O-])n1 CHEMBL4853486 IC50 145.4 nM
Cc1cn(CCCN(C)C)c2ccc(-c3nc(S(C)(=O)=O)nc4[nH]ccc34)cc12 CHEMBL4861221 IC50 157.3 nM
CN(C)CCc1ccc(Nc2cnn(C)c(=O)c2Cl)cc1 CHEMBL4848138 IC50 170.0 nM
N#CCn1ncc(Nc2ccc(CN)cc2)c(Cl)c1=O CHEMBL4863631 Kd 200.0 nM
Cn1ncc(Nc2ccccc2CN)c(Cl)c1=O CHEMBL4101756 IC50 220.0 nM
Cn1ncc(Nc2ccc3c(c2)CCNC3)c(Cl)c1=O CHEMBL4850516 IC50 250.0 nM
CCC(C)Nc1cc(-c2ccc3c(ccn3CCCN(C)C)c2)nc(S(C)(=O)=O)n1 CHEMBL4863921 IC50 287.6 nM
Cn1ncc(Nc2ccc(CN)cc2)c(Cl)c1=O CHEMBL4866748 IC50 290.0 nM
CN(C)Cc1ccc(Nc2cnn(C)c(=O)c2Cl)cc1 CHEMBL4870218 IC50 310.0 nM
Cn1ncc(Nc2ccc3c(c2)CNCC3)c(Cl)c1=O CHEMBL4848082 IC50 370.0 nM
CN1C[C@H](Nc2nc3c(c(=O)n2C)CCC3)C[C@H](c2ccccc2)C1 CHEMBL4846718 Kd 428.0 nM
CCn1ncc(Nc2ccc(CN)cc2)c(Cl)c1=O CHEMBL4877696 IC50 550.0 nM
CNc1cc(-c2ccc3[nH]ccc3c2)nc(S(C)(=O)=O)n1 CHEMBL4861375 IC50 698.3 nM
Cn1ncc(Nc2ccc(F)cc2)c(Cl)c1=O CHEMBL4850913 IC50 700.0 nM
CC(C)n1ncc(Nc2ccc(CN)cc2)c(Cl)c1=O CHEMBL4863529 IC50 790.0 nM
Cn1ncc(Nc2cccc(CN)c2)c(Cl)c1=O CHEMBL4855881 IC50 800.0 nM
CN1C[C@H](Nc2nc3cc[nH]c3c(=O)n2C)C[C@H](c2ccc3c(c2)OCCO3)C1 CHEMBL4574669 Kd 917.0 nM
Cn1ncc(Nc2ccccc2)c(Cl)c1=O CHEMBL4065579 IC50 950.0 nM
CC(=O)NCc1ccc(Nc2cnn(C)c(=O)c2Cl)cc1 CHEMBL4877118 IC50 970.0 nM