Cc1cc2c(cc1N1C(=O)c3cccc4c(CCCO)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4086276 IC50 6.0 nM
CCCOc1cc(OCCCCN(C)C)cc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)c1 CHEMBL3774575 Kd 12.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4c(Cl)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4075478 IC50 37.0 nM
COc1cc(C#N)ccc1S(=O)(=O)Nc1ccc2c(c1)cc(C)c(=O)n2C CHEMBL3752151 IC50 46.0 nM
Cc1cc2cc(NS(=O)(=O)c3ccc(C#N)cc3)ccc2n(C)c1=O CHEMBL4102050 IC50 48.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4c(Br)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4086958 IC50 51.0 nM
COC1CCN(c2ccc3c4c(cccc24)C(=O)N(c2cc4c(cc2C)n(C)c(=O)n4C)C3=O)CC1 CHEMBL4104538 IC50 53.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4c(N5CCOCC5)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4067968 IC50 61.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4cc(N)cc(c34)C1=O)n(C)c(=O)n2C CHEMBL4076603 IC50 63.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4c(N5CCC(O)CC5)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4065133 IC50 66.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4c(CCCCO)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4059651 IC50 70.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4c(N5CCN(CCN(C)C)CC5)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4064164 IC50 74.0 nM
COc1cc2c(cc1NS(=O)(=O)c1ccc(C#N)cc1OC)cc(C)c(=O)n2C CHEMBL4103077 IC50 80.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4c(N5CCN(CC6CC6)CC5)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4076067 IC50 80.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4cc([N+](=O)[O-])cc(c34)C1=O)n(C)c(=O)n2C CHEMBL4068180 IC50 82.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4c(N(C)CCN5CCCC5)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4091912 IC50 84.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4c(N5CCN(C)CC5)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4072812 IC50 93.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4cccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4098824 IC50 94.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4c(N5CCCCC5)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4092917 IC50 95.0 nM
COc1cc2c(cc1NS(=O)(=O)c1ccc(C#N)cc1)cc(C)c(=O)n2C CHEMBL4059962 IC50 100.0 nM
CN(C)c1cc2c(cc1N1C(=O)c3cccc4cccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4064292 IC50 100.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4cc(O)cc(c34)C1=O)n(C)c(=O)n2C CHEMBL4077317 IC50 102.0 nM
CN1C[C@H](Nc2cnn(C)c(=O)c2Br)C[C@H](c2ccccc2)C1 CHEMBL4069412 Ki 110.0 nM
COc1cc2c(cc1N1C(=O)c3cccc4cccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4080780 IC50 115.0 nM
CCCNc1ccc2c3c(cccc13)C(=O)N(c1cc3c(cc1C)n(C)c(=O)n3C)C2=O CHEMBL4062266 IC50 121.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4cc(Br)cc(c34)C1=O)n(C)c(=O)n2C CHEMBL4081145 IC50 124.0 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)N[C@@](C)(C4CC4)C3=O)ccc2Br)C1 CHEMBL4449894 pKd 125.89 nM
Cc1cc2c(cc1N1C(=O)c3cccc4c(N5CCCC5)ccc(c34)C1=O)n(C)c(=O)n2C CHEMBL4063112 IC50 126.0 nM
COc1cc2c(cc1NS(=O)(=O)c1ccc(Br)cc1C)n(C)c(=O)n2C CHEMBL3770173 IC50 127.6 nM
COc1ccccc1S(=O)(=O)Nc1ccc2c(c1)cc(C)c(=O)n2C CHEMBL4069814 IC50 130.0 nM
Cc1cc(=O)n(C)c2ccc(NS(=O)(=O)c3ccc(C#N)cc3)cc12 CHEMBL4061727 IC50 150.0 nM
Cn1c(=O)ccc2cc(S(=O)(=O)Nc3ccc(C#N)cc3)ccc21 CHEMBL4064071 IC50 150.0 nM
Cn1c(=O)n(C)c2cc(N3C(=O)c4cccc5cccc(c45)C3=O)c(Br)cc21 CHEMBL4075962 IC50 153.0 nM
COc1cc2c(cc1NS(=O)(=O)c1ccccc1)cc(C)c(=O)n2C CHEMBL4087315 IC50 190.0 nM
Cn1c(=O)ccc2cc(NS(=O)(=O)c3ccc(C#N)cc3)ccc21 CHEMBL4076056 IC50 200.0 nM
Cn1c(=O)ccc2cc(NS(=O)(=O)c3ccc(Cl)c(Cl)c3)ccc21 CHEMBL4099455 IC50 230.0 nM
Cc1cc2c(cc1N1C(=O)c3cccc4cc(C#N)cc(c34)C1=O)n(C)c(=O)n2C CHEMBL4099171 IC50 248.0 nM
Cn1c(=O)ccc2cc(NS(=O)(=O)c3cccc(C#N)c3)ccc21 CHEMBL4103432 IC50 270.0 nM
CN1CCN(c2cc3c(cc2N2C(=O)c4cccc5cccc(c45)C2=O)n(C)c(=O)n3C)CC1 CHEMBL4064184 IC50 366.0 nM
COc1cc2c(ccc(=O)n2C)cc1NS(=O)(=O)c1ccccc1 CHEMBL4084805 IC50 380.0 nM
Cc1cncc(-c2cnc(N[C@@H]3CCN(C)C[C@H]3OCC3CCS(=O)(=O)CC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL3590408 pKi 398.11 nM
COc1cc(OC)c2c(=O)[nH]c(-c3ccc(OCCOc4ccccc4C(N)=O)cc3)nc2c1 CHEMBL5205994 IC50 440.0 nM
Cn1c(=O)n(C)c2cc(N3C(=O)c4cccc5cccc(c45)C3=O)ccc21 CHEMBL4077619 IC50 450.0 nM
Cn1c(=O)ccc2cc(NS(=O)(=O)c3ccc(C#N)c(Cl)c3)ccc21 CHEMBL4081438 IC50 450.0 nM
COc1cc(C#N)ccc1S(=O)(=O)Nc1cc(F)c2c(c1)cc(C)c(=O)n2C CHEMBL4105505 IC50 510.0 nM
COc1ccccc1C(=O)Nc1cc2c(cc1N1CCCC1)n(C)c(=O)n2C CHEMBL3356143 Kd 512.86 nM
COc1cc2c(ccc(=O)n2C)cc1NS(=O)(=O)c1ccc(C#N)cc1 CHEMBL4102751 IC50 520.0 nM