COc1cc(-c2cn(C)c(=O)c3cnccc23)cc(OC)c1CN(C)C CHEMBL3823478 Kd 0.3 nM
Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O CHEMBL4872300 Kd 0.76 nM
COc1cc(-c2cn(C)c(=O)c3cnccc23)cc(OC)c1CN1CCN(CCCCCOc2cc(-c3scnc3C)ccc2CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)CC1 CHEMBL5182441 DC50 4.5 nM
Cc1c(NCc2ccccc2N2CCN(C)CC2)cnn(C)c1=O CHEMBL4648548 pKi 25.12 nM
COc1cc(-c2cn(C)c(=O)c(C)c2C)cc(OC)c1CN(C)C CHEMBL3823599 IC50 41.0 nM
COc1cc(-c2cn(C)c(=O)c3cnccc23)c(OC)cc1CN(C)C CHEMBL3823101 Kd 73.0 nM
Cc1cc2cc(NS(=O)(=O)c3ccc(C#N)cc3)ccc2n(C)c1=O CHEMBL4102050 IC50 82.0 nM
COc1cc(-c2cn(C)c(=O)c3cnccc23)c(OC)cc1CN(C)CC(=O)NCCOCCOCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O CHEMBL4643109 pIC50 100.0 nM
C/C=C/Cn1cc(-c2cc(OC)c(C(=O)N3CCOCC3)cc2OC)c2cc[nH]c2c1=O CHEMBL4635496 pKd 100.0 nM
COc1cc(-c2cn(C)c(=O)c3ccccc23)cc(OC)c1CN(C)C CHEMBL3824146 IC50 108.0 nM
C/C=C/Cn1cc(-c2cc(OC)c(C(=O)N3CCOCC3)cc2OC)c2cc(C)[nH]c2c1=O CHEMBL5268484 Kd 110.0 nM
Cc1[nH]c(C(=O)Nc2cc(S(=O)(=O)N3CCOCC3)ccc2OCCCCCCCC(=O)NO)c2c1C(=O)CCCC2 CHEMBL5083849 Kd 125.0 nM
COc1cc(C#N)ccc1S(=O)(=O)Nc1ccc2c(c1)cc(C)c(=O)n2C CHEMBL3752151 IC50 140.0 nM
CCn1cc(-c2cccc(C(F)(F)F)c2)c2sc(C(=N)NC3CCS(=O)(=O)CC3)cc2c1=O CHEMBL3769507 Kd 148.0 nM
COc1ccc(-c2ccc3c(C)cc(=O)n(C)c3c2)c(C)n1 CHEMBL5413197 Ki 170.0 nM
COc1cc(-c2cn(C)c(=O)c3cncnc23)cc(OC)c1CN(C)C CHEMBL3824312 IC50 188.0 nM
C/C=C/Cn1cc(-c2ccc(C(=O)N3CCOCC3)cc2)c2cc[nH]c2c1=O CHEMBL5270178 Kd 200.0 nM
COc1cc(-c2cc(C)c(=O)n(C)c2)cc(OC)c1CN(C)C CHEMBL3822990 IC50 230.0 nM
COc1ccc(S(=O)(=O)n2ccc(/C=C/C(=O)NO)c2)cc1NC(=O)c1[nH]c(C)c2c1CCCCC2=O CHEMBL5080049 Kd 230.0 nM
COc1cc(-c2cc(C)c(=O)n(C)c2C)cc(OC)c1CN(C)C CHEMBL3823697 IC50 240.0 nM
COc1ccc(-c2cn(C)c(=O)c3ccccc23)c(OC)n1 CHEMBL5434122 Ki 310.0 nM
CC(=O)c1cc(-c2cc(C(=O)NC3CC3)ccc2C)c2ncccn12 CHEMBL4065619 pKd 316.23 nM
C/C=C/Cn1cc(-c2ccc(C(C)(C)O)cc2OC)c2cc[nH]c2c1=O CHEMBL5282240 Kd 340.0 nM
COc1ccc(-c2ccc3c(C)cc(=O)n(C)c3c2)c(OC)n1 CHEMBL5412877 Kd 340.0 nM
CC(=O)c1cc(-c2cccc3nccn23)c2cc(N3CCOCC3)ccn12 CHEMBL3740819 Kd 368.0 nM
CCOC(=O)Nc1cc(-c2ccc(C)c(NS(C)(=O)=O)c2)nn2c(C)nnc12 CHEMBL3133807 Kd 392.0 nM
Cc1[nH]c(-c2cc(N)ccc2Cl)c2c1C(=O)CCCC2 CHEMBL5439294 Kd 430.0 nM
CCCCc1c(NCc2ccccc2N2CCN(C)CC2)cnn(C)c1=O CHEMBL4639574 pKi 501.19 nM
C/C=C/Cn1cc(-c2cc(OC)c(C(C)(C)O)cc2OC)c2cc(C)[nH]c2c1=O CHEMBL5289762 Kd 520.0 nM
COc1ccccc1C(=O)Nc1cc2c(cc1N1CCCC1)n(C)c(=O)n2C CHEMBL3356143 Kd 812.83 nM
Cc1cc(C)cc(-c2cn(C)c(=O)c3ccccc23)c1 CHEMBL5407972 Ki 860.0 nM
Cc1cc(=O)n(C)c2cc(N3C(=O)CC[C@H](NS(=O)(=O)CC(C)C)[C@H]3c3ccc(Cl)cc3)ccc12 CHEMBL3753082 Kd 909.0 nM