O=C(Cc1ccc(Cl)cc1)NNC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL57104 EC50 0.19 nM
O[C@@](Cc1nc(CC2(C(F)(F)F)CC2)c[nH]1)(c1ccc(-n2cccn2)cc1)C(F)(F)F CHEMBL1672354 pEC50 0.2109 nM
CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](N)Cc1ccccc1)C(C)C)C(N)=O CHEMBL525577 Ki 0.36 nM
CC(C)(C(N)=O)c1cccc2c1N(S(=O)(=O)c1ccc(OC(F)(F)F)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2023112 IC50 0.5 nM
NC(=O)C1(c2cccc3c2N(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)Cc2ccc(C(F)(F)F)nc2N3)CCC1 CHEMBL2023113 IC50 0.5 nM
CC(C)(O)c1nc(C2(c3cccc4c3N(S(=O)(=O)c3ccc(OC(F)(F)F)cc3)Cc3ccc(C(F)(F)F)nc3N4)CCC2)no1 CHEMBL2023111 IC50 0.6 nM
CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3cccc(-c4noc(CO)n4)c32)cc1 CHEMBL2164581 IC50 0.7 nM
CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3ccc4ncccc4c32)cc1 CHEMBL2179918 IC50 0.7 nM
Cn1cc(-c2cccc3c2N(S(=O)(=O)c2ccc(C(C)(C)C)cc2)Cc2ccc(C(F)(F)F)nc2N3)cn1 CHEMBL2164577 IC50 0.76 nM
CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3cccc(-c4noc(C(C)(C)O)n4)c32)cc1 CHEMBL2164223 IC50 0.9 nM
Cc1cccc2c1N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179911 IC50 0.9 nM
CC(C)(C)Cc1cnc(CCc2ccc(-c3cccc(F)c3C(=O)O)cc2)n1CCOc1cccc(O)c1 CHEMBL4435571 EC50 0.9 nM
COC(=O)c1c(F)cccc1-c1ccc(CCc2ncc(CC(C)(C)C)n2CCC(=O)O)cc1 CHEMBL4461212 EC50 1.0 nM
CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(N)=O CHEMBL413893 IC50 1.1 nM
CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3cccc(-c4ncon4)c32)cc1 CHEMBL2164580 IC50 1.1 nM
C[C@H](O)c1nc(-c2cccc3c2N(S(=O)(=O)c2ccc(C(C)(C)C)cc2)Cc2ccc(C(F)(F)F)nc2N3)no1 CHEMBL2164582 IC50 1.2 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1ccc(Cl)nc1N2 CHEMBL2179908 IC50 1.2 nM
Cc1ccc(Oc2cccc(CC(=O)N3CCNc4nc(C(F)(F)F)ccc4C3)c2)cc1 CHEMBL3115400 EC50 1.3 nM
O=C(Cc1cccnc1)NNC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL56369 EC50 1.4 nM
CC(C)(O)c1nc(C(C)(C)c2cccc3c2N(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)Cc2ccc(C(F)(F)F)nc2N3)no1 CHEMBL2023110 IC50 1.4 nM
CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3cccc(C4CCNCC4)c32)cc1 CHEMBL2164578 IC50 1.4 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2164575 IC50 1.4 nM
CC(C)(O)c1nc(-c2cccc3c2N(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)Cc2ccc(C(F)(F)F)nc2N3)no1 CHEMBL2023109 EC50 1.4 nM
O=C(N/N=C/c1ccco1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL57438 EC50 1.5 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)C)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179473 IC50 1.6 nM
O=C(O)C[C@@H]1c2ccc(C(F)(F)F)nc2NCCN1C(=O)Cc1cccc(Oc2ccccc2)c1 CHEMBL3115386 EC50 1.6 nM
CC(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3cccc(-c4noc(C(C)(C)O)n4)c32)cc1 CHEMBL2164224 IC50 1.7 nM
Cc1ccc(Oc2cccc(CC(=O)N3CCNc4nc(C(F)(F)F)ccc4[C@H]3CC(=O)O)c2)cn1 CHEMBL3115390 EC50 1.7 nM
O=C(O)C[C@@H]1c2ccc(C(F)(F)F)nc2NCCN1C(=O)Cc1cccc(Oc2ccc(F)cc2)c1 CHEMBL3115388 EC50 1.7 nM
CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3cccc(-c4cccnc4)c32)cc1 CHEMBL2164576 IC50 1.72 nM
C[C@@H](O)c1nc(-c2cccc3c2N(S(=O)(=O)c2ccc(C(C)(C)C)cc2)Cc2ccc(C(F)(F)F)nc2N3)no1 CHEMBL2164222 IC50 1.9 nM
CC(C)(C)Cc1cnc(CCc2ccc(-c3cccc(F)c3C(=O)O)cc2)n1CCNS(C)(=O)=O CHEMBL4448589 EC50 2.0 nM
C[C@H](NC(=O)Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144501 EC50 2.1 nM
CNC(=O)C1(c2cccc3c2N(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)Cc2ccc(C(F)(F)F)nc2N3)CCC1 CHEMBL2023114 IC50 2.1 nM
O=C(Cc1cc2ccccc2[nH]1)NNC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL294647 EC50 2.2 nM
CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3cccc(O)c32)cc1 CHEMBL2179916 IC50 2.2 nM
C=CC(C)(C)C(OC(=O)c1ccco1)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5406411 pIC50 2.773 nM
O=C(CNCc1ccc(Cl)cc1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL57039 EC50 2.9 nM
CC(C)(C)Cc1cnc(CCc2ccc(-c3cccc(F)c3C(=O)O)cc2)n1CCO CHEMBL4580739 EC50 3.0 nM
COC(=O)c1c(F)cccc1-c1ccc(CCc2ncc(CC(C)(C)C)n2Cc2ccc(C(=O)O)cc2)cc1 CHEMBL4593256 EC50 3.0 nM
O=C(Cc1ccccc1)NNC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL57559 EC50 3.1 nM
CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3cccc(Cl)c32)cc1 CHEMBL2179912 IC50 3.2 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(OC(F)(F)F)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179476 IC50 3.3 nM
O=C(O)C[C@@H]1c2ccc(C(F)(F)F)nc2NCCN1C(=O)Cc1cccc(C(=O)OCC2CC2)c1 CHEMBL3356412 EC50 3.4 nM
O=C(Cc1cccc(Oc2ccc(F)cc2)c1)N1CCNc2nc(C(F)(F)F)ccc2C1 CHEMBL3115399 EC50 3.6 nM
C[C@H](NCc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144492 EC50 4.0 nM
CCCCOC(=O)c1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3[C@H]2CC(=O)O)c1 CHEMBL3356411 EC50 4.0 nM
CC(C)COC(=O)c1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3[C@H]2CC(=O)O)c1 CHEMBL3356410 EC50 4.2 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1ccc(C#N)nc1N2 CHEMBL2179907 IC50 4.4 nM
C=CC(C)(C)C(OC(=O)c1ccccc1)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5398098 pEC50 4.786 nM
CC(C)(C)Cc1c[nH]c(CC(C)(O)c2ccc(-n3cccn3)cc2)n1 CHEMBL1672353 IC50 5.0 nM
CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3ccc(C(C)(C)O)c(F)c32)cc1 CHEMBL2179915 IC50 5.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccc3OCc3nnn[nH]3)cc2)n1 CHEMBL1094054 IC50 5.3 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(N3CCCC[C@@H]3C(=O)O)cc2)n1 CHEMBL1088409 IC50 5.3 nM
Cc1ccc2c(n1)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179917 IC50 5.3 nM
CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3ccccc32)cc1 CHEMBL2179914 IC50 5.5 nM
CC(C)(C)COC(=O)c1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3[C@H]2CC(=O)O)c1 CHEMBL3356413 EC50 5.6 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)(C)C#N)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179478 IC50 5.7 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)(C)F)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179477 IC50 5.7 nM
Cc1ccc2c(c1)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179913 IC50 5.8 nM
O=C(NNCc1ccc(Cl)cc1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL56626 EC50 6.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccc3OCc3nc(=S)[nH][nH]3)cc2)n1 CHEMBL1086672 IC50 6.1 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(N3CCCC[C@@H]3c3nnn[nH]3)cc2)n1 CHEMBL1088410 IC50 6.2 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3cccc(C)n3)cc2)n1 CHEMBL1091985 IC50 6.3 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(F)(F)F)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179474 IC50 6.8 nM
O=C(Cc1cccc(Oc2cccc(F)c2)c1)N1CCNc2nc(C(F)(F)F)ccc2C1 CHEMBL3115398 EC50 6.8 nM
O=C(Cc1cccc(Oc2ccccc2F)c1)N1CCNc2nc(C(F)(F)F)ccc2C1 CHEMBL3115397 EC50 6.9 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3cccc(N)n3)cc2)n1 CHEMBL1092381 IC50 7.3 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3cccnc3)cc2)n1 CHEMBL1091599 IC50 7.5 nM
C[C@H](NC(=O)Cc1ccc2c(c1)OCO2)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144493 EC50 7.8 nM
O=C(Cc1cccc(OC2CCCCC2)c1)N1CCNc2nc(C(F)(F)F)ccc2C1 CHEMBL3115381 EC50 8.1 nM
CC(C)(O)c1nc(-c2cccc3c2N(S(=O)(=O)c2ccc(C(F)(F)F)cc2)Cc2ccc(C(F)(F)F)nc2N3)no1 CHEMBL2164225 IC50 8.3 nM
O=C(Cc1cccc(Oc2ccccc2)c1)N1CCNc2nc(C(F)(F)F)ccc2C1 CHEMBL3115395 EC50 8.5 nM
CC(C)(C)CC(=O)Oc1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3[C@H]2CC(=O)O)c1 CHEMBL3356407 EC50 8.7 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1cc(F)c(Cl)nc1N2 CHEMBL2179910 IC50 8.9 nM
O=C(CC1NCCc2ccccc21)NNC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL292646 EC50 9.3 nM
Cc1ccc(Oc2cccc(CC(=O)N3CCNc4nc(C(F)(F)F)ccc4C3)c2)cn1 CHEMBL3115373 EC50 9.5 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3cnsc3)cc2)n1 CHEMBL1082471 IC50 10.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc3c(c2)CNC(=O)c2ccccc2-3)n1 CHEMBL1087443 IC50 10.0 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(F)(F)F)s1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179480 IC50 10.0 nM
Cc1ccc2c(n1)Nc1ccc(C)c(C)c1N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)C2 CHEMBL2179484 IC50 10.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccc3C(=O)O)cc2)n1 CHEMBL1089721 IC50 11.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccns3)cc2)n1 CHEMBL1093459 IC50 11.0 nM
CC(O)(Cc1nc(CC2(C(F)(F)F)CC2)c[nH]1)c1ccc(-n2cccn2)cc1 CHEMBL1671874 IC50 11.0 nM
O=C(Cc1cccc(Oc2ccccc2)c1)N1CCNc2nc(C(F)(F)F)ccc2C1CCO CHEMBL3115384 EC50 11.0 nM
CC(C)(C)Cc1cnc(CCc2ccc(-c3cccc(F)c3C(=O)O)cc2)n1CCC(=O)O CHEMBL4451347 EC50 11.0 nM
COC(=O)c1c(F)cccc1-c1ccc(CCc2ncc(CC(C)(C)C)n2CCNS(C)(=O)=O)cc1 CHEMBL4464287 EC50 11.0 nM
O=C(Cc1cccc(Oc2ccccc2)c1)N1CCNc2nc(C(F)(F)F)ccc2C1CO CHEMBL3115382 EC50 12.0 nM
CC(C)CC(=O)Oc1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3[C@H]2CC(=O)O)c1 CHEMBL3356404 EC50 12.0 nM
CC(C)(C)Cc1cnc(CCc2ccc(-c3cccc(F)c3C(=O)O)cc2)n1Cc1ccc(C(=O)O)cc1 CHEMBL4522752 EC50 12.0 nM
COc1cc(C(O)CC=C(C)C)c(OC)c2c1/C(=N/O)C=C/C2=N\O CHEMBL5430646 pIC50 12.47 nM
O=C(O)CC1c2ccc(C(F)(F)F)nc2NCCN1C(=O)Cc1cccc(Oc2ccccc2)c1 CHEMBL3115385 EC50 13.0 nM
COC(=O)c1c(F)cccc1-c1ccc(CCc2ncc(CC(C)(C)C)n2CCOc2cccc(O)c2)cc1 CHEMBL4557722 EC50 13.0 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1csc(C(F)(F)F)c1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179481 IC50 14.0 nM
C=CC(C)(C)C(OC(=O)c1ccccn1)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5404444 pEC50 14.69 nM
O=C(NNCc1ccccc1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL56562 EC50 15.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3cccc(C(=O)O)n3)cc2)n1 CHEMBL1091554 EC50 15.0 nM
c1ccc(-c2nnn[nH]2)c(-c2ccc(CCc3nc(CC4CCCC4)c[nH]3)cc2)c1 CHEMBL1099034 IC50 15.0 nM
C=CC(C)(C)C(OC(=O)c1cccnc1)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5425677 pEC50 15.67 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccc(F)cn3)cc2)n1 CHEMBL1093184 IC50 16.0 nM
O=C(CNCCc1ccccc1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL57068 EC50 17.0 nM
CC(C)(C)Cc1c[nH]c(CC(C)(O)c2ccc(-c3ccc(F)cn3)cc2)n1 CHEMBL1672352 IC50 17.0 nM
CC(C)COc1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3[C@H]2CC(=O)O)c1 CHEMBL3115389 EC50 17.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccn3)cc2)n1 CHEMBL1091720 IC50 18.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(N3CCCc4cn[nH]c43)cc2)n1 CHEMBL1088553 IC50 18.0 nM
CC(C)(O)c1nc(-c2cccc3c2N(S(=O)(=O)c2ccc(OC(F)F)cc2)Cc2ccc(C(F)(F)F)nc2N3)no1 CHEMBL2164226 IC50 18.0 nM
O=C(CC1NCCc2ccccc21)NNC(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL175651 EC50 19.0 nM
CCCCC(=O)Oc1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3[C@H]2CC(=O)O)c1 CHEMBL3356405 EC50 19.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc3c(c2)CN(C)C(=O)c2ccccc2-3)n1 CHEMBL1087200 IC50 20.0 nM
Cc1ccc2c(c1C)N(S(=O)(=O)C1=NC(C(C)(C)C)C=[S+]1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179479 IC50 20.0 nM
O=C(CNCc1cccnc1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL292176 EC50 21.0 nM
O=C(CNCc1ccccc1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL417767 EC50 21.0 nM
COC(=O)c1c(F)cccc1-c1ccc(CCc2ncc(CC(C)(C)C)n2CCO)cc1 CHEMBL4482945 EC50 21.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccc3OCc3ncn[nH]3)cc2)n1 CHEMBL1086673 IC50 22.0 nM
O=C(NNCc1ccco1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL418147 EC50 24.0 nM
C[C@H](NCCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144491 EC50 25.0 nM
O=C(Cc1cccc(Oc2ccccc2)c1)N1Cc2ccc(C(F)(F)F)nc2Nc2ccccc21 CHEMBL3115394 EC50 25.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(N3CCCC[C@@H]3c3ncn[nH]3)cc2)n1 CHEMBL1088411 IC50 26.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccc3OCc3nc(N)n[nH]3)cc2)n1 CHEMBL1086674 IC50 27.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(N3CCCCC3)cc2)n1 CHEMBL1091918 IC50 28.0 nM
CC(C)(C)c1ccc(S(=O)(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3cccc(-c4noc(=O)[nH]4)c32)cc1 CHEMBL2164579 IC50 29.0 nM
O=C(CN1CCC(Cc2ccccc2)CC1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL60537 EC50 30.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccc3O)cc2)n1 CHEMBL1088684 IC50 31.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccc3OCc3nc(=O)[nH][nH]3)cc2)n1 CHEMBL1086684 IC50 31.0 nM
C[C@H](NC(=O)Cc1cccnc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144500 EC50 32.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-n3cccn3)cc2)n1 CHEMBL1089521 IC50 33.0 nM
O=C(O)c1cc(F)c(F)cc1-c1ccc(CCc2nc(CC3CCCCC3)c[nH]2)cc1 CHEMBL1092730 IC50 36.0 nM
CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)COCC(=O)Nc1ccc(CC(CNCCN)CNCCN)cc1)C(C)C)C(N)=O CHEMBL414307 IC50 37.0 nM
CC(C)(C)CCc1cnc(CCc2ccc(-c3ccccc3C(=O)O)cc2)[nH]1 CHEMBL1089382 EC50 39.0 nM
COC(=O)c1c(F)cccc1-c1ccc(CCc2ncc(CC(C)(C)C)n2CC(=O)O)cc1 CHEMBL4514194 EC50 39.0 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1cccnc1N2 CHEMBL2179482 IC50 40.0 nM
CC(C)OC(=O)c1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3[C@H]2CC(=O)O)c1 CHEMBL3356409 EC50 40.0 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(CC3CCCCC3)[nH]2)cc1 CHEMBL1099032 EC50 41.0 nM
O=C(Cc1cccc(OC2CCCC2)c1)N1CCNc2nc(C(F)(F)F)ccc2C1 CHEMBL3115380 EC50 41.0 nM
O=C(O)C[C@@H]1c2ccc(C(F)(F)F)nc2NCCN1C(=O)Cc1cccc(OC(=O)CC2CC2)c1 CHEMBL3356406 EC50 42.0 nM
CCC(C)(C)Cc1cnc(CCc2ccc(-c3ccccn3)cc2)n1CC(=O)O CHEMBL4449347 EC50 42.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3csnn3)cc2)n1 CHEMBL1089511 IC50 45.0 nM
C[C@H](NCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144495 EC50 46.0 nM
CC(C)(C)c1ccc(CC(=O)N2Cc3ccc(C(F)(F)F)nc3Nc3ccccc32)cc1 CHEMBL3115392 EC50 48.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3cccc(O)n3)cc2)n1 CHEMBL1093170 IC50 51.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3cnccn3)cc2)n1 CHEMBL1089512 IC50 51.0 nM
CCC(C)(C)NC(=O)NS(=O)(=O)c1cnccc1N[C@@H]1C[C@H]2CC[C@@H]1C2 CHEMBL1762250 EC50 51.0 nM
C=CC(C)(C)C(OC(=O)CC(C)C)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5414271 pEC50 52.48 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccc3OCC(=O)O)cc2)n1 CHEMBL1088686 EC50 54.0 nM
CC(C)(C)NC(=O)NS(=O)(=O)c1cnccc1N[C@@H]1C[C@H]2CC[C@@H]1C2 CHEMBL1762247 EC50 55.0 nM
NC(=O)CC[C@H](NC(=O)Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144499 EC50 57.0 nM
CCCCOc1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3C2)c1 CHEMBL3115377 EC50 59.0 nM
C=CC(C)(C)C(OC(=O)c1cncc(F)c1)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5422040 pEC50 59.98 nM
O=S(=O)(Nc1nc(C2CCC2)n[nH]1)c1cnccc1NC1CC2CCC1C2 CHEMBL1762274 IC50 68.0 nM
CC(C)C(=O)Oc1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3[C@H]2CC(=O)O)c1 CHEMBL3356403 EC50 68.0 nM
CC(C)(C)Cc1cnc(CCc2ccc(-c3cccc(F)c3C(=O)O)cc2)n1CC(=O)O CHEMBL4476111 EC50 69.0 nM
O=C(CN1CCN(Cc2ccccc2)CC1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL293820 EC50 70.0 nM
CC(C)COc1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3C2)c1 CHEMBL3115378 EC50 70.0 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(S(C)(=O)=O)cc1)Cc1ccc(C(F)(F)F)nc1N2 CHEMBL2179475 IC50 73.0 nM
CCC(C)(CC)Cc1cnc(CCc2ccc(-c3ccccc3C(=O)O)cc2)[nH]1 CHEMBL1093080 EC50 76.0 nM
C[C@H](NC(=O)Cc1cc2ccccc2[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144490 EC50 79.0 nM
C=CC(C)(C)C(OC(=O)c1ccc(C)cc1)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5431181 pEC50 81.66 nM
CC(C)(C)Cc1c[nH]c(C(C)(O)Cc2ccc(-c3ccc(F)cn3)cc2)n1 CHEMBL1672351 IC50 82.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccc3OCc3cnn[nH]3)cc2)n1 CHEMBL1087442 IC50 83.0 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(Cc3cccc(F)c3F)[nH]2)cc1 CHEMBL1084696 EC50 87.0 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(CC3CCCCCC3)[nH]2)cc1 CHEMBL1099033 EC50 88.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-n3cncn3)cc2)n1 CHEMBL1089522 EC50 89.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-n3ncnn3)cc2)n1 CHEMBL1091917 EC50 89.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-n3ccnn3)cc2)n1 CHEMBL1089523 EC50 93.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3cccnc3C(=O)O)cc2)n1 CHEMBL1091553 EC50 95.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccncc3)cc2)n1 CHEMBL1091984 EC50 95.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3cccc(C#N)n3)cc2)n1 CHEMBL1093183 EC50 95.0 nM
c1ccc(-c2ccc(CCc3nc(CC4CCCC4)c[nH]3)cc2)nc1 CHEMBL1091598 EC50 98.0 nM
C=CC(C)(C)C(OC(=O)c1cccnc1Br)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5405083 pEC50 101.39 nM
CC(C)(C)Cc1cnc(CCc2ccc(-c3ccccc3C(=O)O)cc2)[nH]1 CHEMBL1089383 EC50 106.0 nM
CC(C)CCc1cnc(CCc2ccc(-c3ccccc3C(=O)O)cc2)[nH]1 CHEMBL1091468 EC50 119.0 nM
Cc1ccccc1Cc1cnc(CCc2ccc(-c3ccccc3C(=O)O)cc2)[nH]1 CHEMBL1082543 EC50 127.0 nM
CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccc3OCc3nc(C(F)(F)F)n[nH]3)cc2)n1 CHEMBL1087066 IC50 127.0 nM
CC(C)C1CN(Cc2ccccc2)c2ccccc2CN1C(=O)Nc1cccc(N2CCOCC2)c1 CHEMBL3115369 EC50 131.0 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(CC3CCCC3)[nH]2)cc1 CHEMBL1084942 EC50 133.0 nM
C=CC(C)(C)C(OC(=O)C1CCCO1)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5395420 pEC50 134.59 nM
C[C@H](NC(=O)Cc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144489 EC50 140.0 nM
CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CCNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccc(O)cc1)C(C)C)C(=O)O CHEMBL262992 EC50 151.0 nM
O=C(Cc1cccc(Oc2cccnc2)c1)N1CCNc2nc(C(F)(F)F)ccc2C1 CHEMBL3115371 EC50 156.0 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(Cc3cccc(F)c3)[nH]2)cc1 CHEMBL1088614 EC50 159.0 nM
CC(C)(C)NC(=O)NS(=O)(=O)c1cnccc1N[C@H]1C[C@H]2CC[C@@H]1C2 CHEMBL1762248 EC50 160.0 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(Cc3ccccc3F)[nH]2)cc1 CHEMBL1088062 EC50 177.0 nM
CC(C)(C)COc1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3C2)c1 CHEMBL3115379 EC50 199.0 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(Cc3ccccc3)[nH]2)cc1 CHEMBL1085434 EC50 205.0 nM
COc1ccc2nc(CCc3cc4c(cc3Cl)OCO4)[nH]c2c1 CHEMBL450593 EC50 210.0 nM
CC(C)NC(=O)NS(=O)(=O)c1cnccc1NC1CC2CCC1C2 CHEMBL1348293 EC50 220.0 nM
O=C(NC12CC3CC(CC(C3)C1)C2)NS(=O)(=O)c1cnccc1N[C@@H]1C[C@H]2CC[C@@H]1C2 CHEMBL1762252 EC50 220.0 nM
C=CC(C)(C)C(OCCCCO)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5414856 pEC50 226.46 nM
NC(=O)CC[C@H](NC(=O)CCc1ccc(Cl)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144502 EC50 230.0 nM
CC1(CN2CCC(n3c(=O)[nH]c4ccccc43)CC2)OCc2ccccc2-n2cccc21 CHEMBL5483013 EC50 240.0 nM
FC(F)(F)c1ccc2nc(COc3cc4c(cc3Cl)OCO4)[nH]c2c1 CHEMBL513374 EC50 240.0 nM
CC(C)(C)c1cc(NS(=O)(=O)c2cnccc2N[C@@H]2C[C@H]3CC[C@@H]2C3)[nH]n1 CHEMBL1762271 IC50 250.0 nM
O=C(Cc1cccc(Oc2ccccn2)c1)N1CCNc2nc(C(F)(F)F)ccc2C1 CHEMBL3115401 EC50 254.0 nM
C=CC(C)(C)C(OC(=O)c1ccncc1)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5411592 pEC50 277.33 nM
O=C1NC(=O)C(c2ccccc2-c2ccc(CCC3N=CC(CC4CCCC4)=N3)cc2)S1 CHEMBL1088685 IC50 287.0 nM
O=S(=O)(Nc1nc(C2CCC2)n[nH]1)c1cnccc1N[C@@H]1C[C@H]2CC[C@@H]1C2 CHEMBL1762273 IC50 290.0 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(Cc3ccccc3Cl)[nH]2)cc1 CHEMBL1080581 EC50 292.0 nM
CC(C)(C)NC(=O)NS(=O)(=O)c1cnccc1N[C@H]1C[C@H]2CC[C@]1(C)C2(C)C CHEMBL1762255 IC50 300.0 nM
C[C@H](NC(=O)CC1NCCc2ccccc21)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144496 EC50 310.0 nM
C=CC(C)(C)C(OC(=O)c1ccc(C=O)cc1)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5429857 pEC50 311.17 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(CC3CCOCC3)[nH]2)cc1 CHEMBL1097363 EC50 338.0 nM
COc1ccc2nc(C(C)Cc3cc4c(cc3Cl)OCO4)[nH]c2c1 CHEMBL501895 EC50 350.0 nM
CC(C)(C)CC(C)(C)NC(=O)NS(=O)(=O)c1cnccc1N[C@@H]1C[C@H]2CC[C@@H]1C2 CHEMBL1762251 EC50 350.0 nM
O=C(Cc1ccc(Oc2ccccc2)cc1)N1Cc2ccc(C(F)(F)F)nc2Nc2ccccc21 CHEMBL3115393 EC50 368.0 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(C3CCCCC3)[nH]2)cc1 CHEMBL1097362 EC50 375.0 nM
COc1ccc2nc(SCc3cc4c(cc3Cl)OCO4)[nH]c2c1 CHEMBL527650 EC50 380.0 nM
CC(C)Oc1cccc(CC(=O)N2CCNc3nc(C(F)(F)F)ccc3C2)c1 CHEMBL3115376 EC50 381.0 nM
CC(C)(C)NC(=O)NS(=O)(=O)c1cnccc1NC1CCCCC1 CHEMBL1762253 IC50 400.0 nM
Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1cc(Cl)cnc1N2 CHEMBL2179909 IC50 430.0 nM
CC(C)NC(=O)NS(=O)(=O)c1cnccc1N[C@@H]1C[C@H]2CC[C@@H]1C2 CHEMBL1762245 EC50 440.0 nM
COc1ccc2nc(COc3cc4c(cc3Cl)OCO4)[nH]c2c1 CHEMBL469313 EC50 510.0 nM
CC(C)(C)c1cccc(NS(=O)(=O)c2cnccc2N[C@@H]2C[C@H]3CC[C@@H]2C3)c1 CHEMBL1762269 IC50 520.0 nM
COc1cc(C(CC=C(C)C)OCCC(C)C)c(OC)c2c1/C(=N/O)C=C/C2=N\O CHEMBL5421389 pEC50 520.0 nM
CCC(C)(C)C(=O)Nc1n[nH]c2nc(N3CCCCC3)c3c(c12)CCN(Cc1ccccc1)C3 CHEMBL1099135 EC50 543.0 nM
Clc1ccc2nc(COc3cc4c(cc3Cl)OCO4)[nH]c2c1 CHEMBL471016 EC50 570.0 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(CC3CCC3)[nH]2)cc1 CHEMBL1084698 EC50 588.0 nM
CC(C)(C)NC(=O)NS(=O)(=O)c1cnccc1N[C@H]1C[C@@H]2CC[C@H]1C2 CHEMBL1762249 IC50 630.0 nM
CN(C(=O)NS(=O)(=O)c1cnccc1N[C@@H]1C[C@H]2CC[C@@H]1C2)C(C)(C)C CHEMBL1762266 EC50 640.0 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(CCC3CCCCC3)[nH]2)cc1 CHEMBL1099370 EC50 642.0 nM
COC(=O)c1ccccc1-c1ccc(CCc2ncc(CC(C)(C)C)[nH]2)cc1 CHEMBL4544477 EC50 644.0 nM
CC(C)(C)NC(=O)NS(=O)(=O)c1cnccc1N[C@@H]1C[C@H]2CC[C@]1(C)C2(C)C CHEMBL1762254 IC50 660.0 nM
O=C(Nc1n[nH]c2nc(N3CCCCC3)c3c(c12)CCN(Cc1ccccc1)C3)C1CCCC1 CHEMBL1098838 EC50 704.0 nM
NC(=O)CC[C@H](NC(=O)[C@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 CHEMBL3144497 EC50 710.0 nM
CC(C)c1n[nH]c(NS(=O)(=O)c2cnccc2N[C@@H]2C[C@H]3CC[C@@H]2C3)n1 CHEMBL1762272 IC50 770.0 nM
C=CC(C)(C)C(OCCCCCO)c1cc(OC)c2c(c1OC)/C(=N/O)C=C/C2=N\O CHEMBL5403261 pEC50 776.25 nM
N#Cc1cccc(Cc2cnc(CCc3ccc(-c4ccccc4C(=O)O)cc3)[nH]2)c1 CHEMBL1082542 EC50 812.0 nM
CC(C)NC(=O)NS(=O)(=O)c1cnccc1N[C@H]1C[C@H]2CC[C@@H]1C2 CHEMBL1762246 IC50 820.0 nM
COc1cc(C(CC=C(C)C)OC(=O)CC(C)C)c(OC)c2c1/C(=N/O)C=C/C2=N\O CHEMBL5432370 pEC50 822.24 nM
O=C(O)c1ccccc1-c1ccc(CCc2ncc(Cc3cccc(Cl)c3)[nH]2)cc1 CHEMBL1086913 EC50 825.0 nM
CC(C)(C)NC(=O)NS(=O)(=O)c1cnccc1O[C@@H]1C[C@@H]2CC[C@H]1C2 CHEMBL1762262 IC50 880.0 nM
CC(C)(C)Cc1cnc(CCc2ccc(-c3ccccc3C(=O)O)cc2)n1CC(=O)O CHEMBL4590481 EC50 897.0 nM
CC(=O)N1Cc2ccccc2N(Cc2ccccc2)CC1C(C)C CHEMBL3115370 EC50 916.0 nM
COC(=O)c1ccccc1-c1ccc(CCc2ncc(CC(C)(C)C)n2CC(=O)O)cc1 CHEMBL4522974 EC50 968.0 nM
O=C(Cc1cccc(Oc2ccncc2)c1)N1CCNc2nc(C(F)(F)F)ccc2C1 CHEMBL3115372 EC50 977.0 nM
CC(C)(C)NC(=O)NS(=O)(=O)c1cnccc1O[C@@H]1C[C@H]2CC[C@@H]1C2 CHEMBL1762261 IC50 990.0 nM