N=C(N)c1cc2ccc(OC(=O)c3cccs3)cc2s1 CHEMBL2220483 IC50 1.6 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2cccc(C=O)c2)c1 CHEMBL4244141 Ki 6.0 nM
Cc1cc([C@H]2CN(c3ccc4c(N)nncc4c3)CCN2c2cccc(F)c2)no1 CHEMBL5435382 IC50 7.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2Cc1cc(F)ccc1F CHEMBL205904 Ki 10.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=NS(=O)(=O)c1cccc(NC(N)=O)c1)c1cccc(-c2c(C)cc(NC(=N)N)cc2N)c1 CHEMBL4242095 Ki 11.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2NC(=O)CCCS(C)(=O)=O)c1 CHEMBL399284 Ki 14.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2Cc1c(Cl)cccc1Cl CHEMBL377090 Ki 20.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2N)c1 CHEMBL401398 Ki 20.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2NC(=O)NCCCCCC(=O)O)c1 CHEMBL403782 Ki 22.0 nM
N=C(N)Nc1ccc(C(=O)Oc2ccc3cc(C(=N)N)ccc3c2)cc1 CHEMBL273264 IC50 29.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2Cc1cc([N+](=O)[O-])ccc1F CHEMBL377281 Ki 30.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2Cc1ccccc1 CHEMBL438807 Ki 30.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2ccccc2C)c1 CHEMBL413993 Ki 30.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2cccc(NS(=O)(=O)c3ccc(F)cc3F)c2)cs1 CHEMBL4239924 Ki 30.0 nM
Cc1cc([C@H]2CN(c3cc(F)c4c(N)nncc4c3)CCN2c2cccc(F)c2)no1 CHEMBL5417464 IC50 36.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2Cc1c(F)cccc1F CHEMBL382350 Ki 40.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2cccc(C)n2)c1 CHEMBL252004 Ki 40.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2ccccc2Cl)c1 CHEMBL252998 Ki 40.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2NC(=O)CCCCC(=O)O)c1 CHEMBL252203 Ki 42.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2CC=C(C)C CHEMBL206020 Ki 50.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2CO)c1 CHEMBL253646 Ki 50.0 nM
CCCc1c(-c2csc(-c3cc(C(=N)N)sc3SC)n2)cnn1-c1ccccc1 CHEMBL319394 Ki 60.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2NC(=O)NCCc2nn[nH]n2)c1 CHEMBL254283 Ki 64.0 nM
CCCOc1c(-c2csc(-c3cc(C(=N)N)sc3SC)n2)cnn1-c1ccccn1 CHEMBL317917 Ki 70.0 nM
C=CCn1cnc2cc(S(=O)(=O)c3cc(C(=N)N)sc3SC)cc(Br)c21 CHEMBL381771 Ki 70.0 nM
CCCc1c(-c2csc(-c3cc(C(=N)N)sc3SC)n2)cnn1-c1ccccn1 CHEMBL3901198 Ki 70.0 nM
CCOc1c(-c2csc(-c3cc(C(=N)N)sc3SC)n2)cnn1-c1ccccc1 CHEMBL321341 Ki 90.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Cl)c2c(c1)ncn2Cc1c(F)cccc1F CHEMBL382443 Ki 100.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Cl)c2ncn(Cc3c(F)cccc3F)c2c1 CHEMBL205385 Ki 100.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2NC(=O)CS(C)(=O)=O)c1 CHEMBL252619 Ki 120.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2ccccc2CO)c1 CHEMBL252794 Ki 120.0 nM
C=Cc1ccccc1-c1cccc(S(=O)(=O)c2cc(C(=N)N)sc2SC)c1 CHEMBL253430 Ki 140.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2cnn(-c3ccccc3)c2)cs1 CHEMBL322834 Ki 150.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2c(C)cccc2C(=O)O)c1 CHEMBL400375 Ki 150.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2cccc(O)c2)c1 CHEMBL252793 Ki 150.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2ncn(Cc3c(Cl)cccc3Cl)c2c1 CHEMBL426490 Ki 160.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2ncn(Cc3cc([N+](=O)[O-])ccc3F)c2c1 CHEMBL381097 Ki 170.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2ncn(Cc3c(F)cccc3F)c2c1 CHEMBL205804 Ki 170.0 nM
C[C@H]1CN(c2ccc3c(N)nncc3c2)CCN1c1cccc(F)c1 CHEMBL5418327 IC50 170.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2ncn(-c3ccccc3)c2c1 CHEMBL205342 Ki 180.0 nM
CCCc1nn(C)cc1-c1csc(-c2cc(C(=N)N)sc2SC)n1 CHEMBL106388 Ki 190.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2ccc(O)cc2)c1 CHEMBL400497 Ki 190.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2ncn(CC=C(C)C)c2c1 CHEMBL380315 Ki 200.0 nM
C=CCn1cnc2c(Br)cc(S(=O)(=O)c3cc(C(=N)N)sc3SC)cc21 CHEMBL377934 Ki 210.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2ncn(Cc3cc(F)ccc3F)c2c1 CHEMBL438267 Ki 240.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2ccc(C)cc2)c1 CHEMBL252591 Ki 250.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2ccccc2)c1 CHEMBL252393 Ki 260.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2-c1ccccc1 CHEMBL204679 Ki 310.0 nM
CCCc1c(-c2csc(-c3cc(C(=N)N)sc3SC)n2)cnn1C CHEMBL318576 Ki 330.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2[C@@H](C)c1ccccc1 CHEMBL205578 Ki 330.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2ncn(C)c2c1 CHEMBL205657 Ki 330.0 nM
COc1ccc(-c2cccc(S(=O)(=O)c3cc(C(=N)N)sc3SC)c2)cc1 CHEMBL415092 Ki 350.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(Br)c1 CHEMBL398527 Ki 360.0 nM
Nc1nncc2cc(N3CCN(c4cccc(F)c4)CC3)ccc12 CHEMBL5407328 IC50 370.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2[C@H](C)c1ccccc1 CHEMBL205354 Ki 380.0 nM
Nc1nncc2cc(N3CCN(c4cccc(Cl)c4)CC3)ccc12 CHEMBL5410431 IC50 390.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1ccc2c(c1)ncn2Cc1ccccc1 CHEMBL204889 Ki 400.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2ncn(Cc3ccccc3)c2c1 CHEMBL379523 Ki 400.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2C CHEMBL380325 Ki 400.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2[nH]cnc2c1 CHEMBL205698 Ki 400.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1ccc2ccccc2c1 CHEMBL380318 Ki 410.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2ccc(C)cc2)cs1 CHEMBL29304 Ki 420.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1ccc2ncn(Cc3ccccc3)c2c1 CHEMBL204936 Ki 420.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2ccc(Cl)cc2)cs1 CHEMBL286243 Ki 436.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2csc3ccccc23)cs1 CHEMBL28875 Ki 450.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2cnn(C)c2)cs1 CHEMBL102417 Ki 460.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2ccccc2O)c1 CHEMBL252592 Ki 460.0 nM
COc1cccc(-c2csc(-c3cc(C(=N)N)sc3SC)n2)c1 CHEMBL29205 Ki 470.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2ccc3ccccc3c2)cs1 CHEMBL29290 Ki 490.0 nM
COc1cccc(-c2cccc(S(=O)(=O)c3cc(C(=N)N)sc3SC)c2)c1 CHEMBL399262 Ki 490.0 nM
CSc1sc(C(=N)N)cc1-c1nc(COc2ccccc2)cs1 CHEMBL287292 Ki 520.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2cnn(-c3ccccc3)c2OCC2CCC2)cs1 CHEMBL102835 Ki 530.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2ccccc2)cs1 CHEMBL281899 Ki 560.0 nM
Cc1cccc(N2CCN(c3ccc4c(N)nncc4c3)CC2)c1 CHEMBL5418278 IC50 560.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1ccc2c(c1)ncn2Cc1ccccn1 CHEMBL382447 Ki 580.0 nM
Nc1nncc2cc(N3CCN(c4ccccc4)CC3)ccc12 CHEMBL5437582 IC50 580.0 nM
COc1ccccc1-c1cccc(S(=O)(=O)c2cc(C(=N)N)sc2SC)c1 CHEMBL401087 Ki 610.0 nM
COc1ccc(-c2csc(-c3cc(C(=N)N)sc3SC)n2)c(OC)c1 CHEMBL286267 Ki 640.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2cccs2)cs1 CHEMBL31549 Ki 700.0 nM
CSc1sc(C(=N)N)cc1S(=O)(=O)c1ccccc1 CHEMBL205489 Ki 750.0 nM
C[C@@H]1CN(c2ccc3c(N)nncc3c2)CCN1c1cccc(F)c1 CHEMBL5432292 IC50 820.0 nM
COc1ccccc1-c1csc(-c2cc(C(=N)N)sc2SC)n1 CHEMBL283080 Ki 850.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2ccccc2C)cs1 CHEMBL28949 Ki 850.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2ccc(Cl)c([N+](=O)[O-])c2)cs1 CHEMBL413764 Ki 860.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2cnccc2Cl)cs1 CHEMBL28723 Ki 870.0 nM
COc1ccc(-c2csc(-c3cc(C(=N)N)sc3SC)n2)cc1 CHEMBL28618 Ki 900.0 nM
CC(C)[C@@H](NC(=O)Cc1c(Cl)cccc1Cl)C(=O)N1CC=CC1C(=O)NCc1ccc(C(=N)N)s1 CHEMBL4247936 IC50 900.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2cccc(C)c2)cs1 CHEMBL286498 Ki 960.0 nM
CSc1sc(C(=N)N)cc1-c1nc(-c2ccc([N+](=O)[O-])cc2)cs1 CHEMBL29006 Ki 1000.0 nM