Cc1cc(C)n(NC(=O)C2CC(=O)N(c3cc(C)c(S(N)(=O)=O)c(C)c3Cl)C2)n1 CHEMBL4461481 Kd 0.011 nM
COC(=O)C1CC(=O)N(c2cc(C)c(S(N)(=O)=O)c(C)c2Cl)C1 CHEMBL4473602 Kd 0.016 nM
Cc1cc(N2CC(C(=O)NNC(=S)Nc3ccccc3)CC2=O)c(Cl)c(C)c1S(N)(=O)=O CHEMBL4464359 Kd 0.016 nM
Cc1cc(N2CC(c3n[nH]c(=S)n3-c3ccccc3)CC2=O)c(Cl)c(C)c1S(N)(=O)=O CHEMBL4539340 Kd 0.019 nM
Cc1cc(N2CC(C(=O)N/N=C/c3ccccc3)CC2=O)c(Cl)c(C)c1S(N)(=O)=O CHEMBL4463683 Kd 0.038 nM
NS(=O)(=O)c1c(F)c(F)c(SCCO)c(F)c1F CHEMBL2333416 Kd 0.05 nM
COc1ccc(/C=N/NC(=O)C2CC(=O)N(c3cc(C)c(S(N)(=O)=O)c(C)c3Cl)C2)cc1 CHEMBL4441730 Kd 0.057 nM
CC(C)(C)c1cc(=O)[nH]c(SCC(=O)c2ccc(S(N)(=O)=O)cc2)n1 CHEMBL2010994 Kd 0.058 nM
Cc1cc(N2CC(C(=O)N/N=C/c3ccc([N+](=O)[O-])cc3)CC2=O)c(Cl)c(C)c1S(N)(=O)=O CHEMBL4555622 Kd 0.063 nM
NS(=O)(=O)c1cc(C(=O)O)c(SCCc2ccccc2)cc1Cl CHEMBL4578934 Kd 0.07 nM
Cc1cc(N2CC(C(=O)N/N=C/c3ccc(Br)cc3)CC2=O)c(Cl)c(C)c1S(N)(=O)=O CHEMBL4475315 Kd 0.076 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1SCCc1ccccc1 CHEMBL4466140 Kd 0.09 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(SCCc2ccccc2)cc1Br CHEMBL4515586 Kd 0.1 nM
Cc1cc(N2CC(c3n[nH]c(=S)o3)CC2=O)c(Cl)c(C)c1S(N)(=O)=O CHEMBL4457904 Kd 0.11 nM
NS(=O)(=O)c1cc(C(=O)O)c(SC2CCCCC2)cc1Cl CHEMBL4543024 Kd 0.12 nM
NC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1SCCc1ccccc1 CHEMBL4456851 Kd 0.13 nM
NS(=O)(=O)c1ccc(NC(=O)C2CC(=O)N(c3ccccc3Br)C2)cc1 CHEMBL4553790 Kd 0.14 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Br)cc1SCCc1ccccc1 CHEMBL4468834 Kd 0.14 nM
Cc1cc(N2CC(C(=O)NNC(=S)Nc3ccccc3)CC2=O)cc(C)c1S(N)(=O)=O CHEMBL4577993 Kd 0.15 nM
NC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1SC1CCCCC1 CHEMBL4586089 Kd 0.15 nM
NS(=O)(=O)c1ccc(C(=O)CSc2ncccn2)cc1Cl CHEMBL2443188 Kd 0.17 nM
NS(=O)(=O)c1ccc(C(=O)Cn2cnc3ccccc32)cc1Cl CHEMBL3798446 Kd 0.19 nM
Cc1cc(NCC(CC(=O)O)c2n[nH]c(=S)n2-c2ccccc2)c(Cl)c(C)c1S(N)(=O)=O CHEMBL4517728 Kd 0.2 nM
NS(=O)(=O)c1c(F)c(F)c(SCCc2ccccc2)c(F)c1F CHEMBL2333406 Kd 0.22 nM
Cc1cc(S(N)(=O)=O)c(C)cc1N1CC(C(=O)N/N=C/c2ccc([N+](=O)[O-])cc2)CC1=O CHEMBL4555586 Kd 0.22 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(NCc2ccccc2)cc1Cl CHEMBL4168966 Kd 0.23 nM
Cc1cc(N2CC(C(=O)NN)CC2=O)c(Cl)c(C)c1S(N)(=O)=O CHEMBL4458989 Kd 0.23 nM
Cc1cc(N2CC(C(=O)N/N=C/c3ccc(Cl)cc3)CC2=O)c(Cl)c(C)c1S(N)(=O)=O CHEMBL4573916 Kd 0.23 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1SC1CCCCC1 CHEMBL4451500 Kd 0.23 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(SC2CCCCC2)cc1Br CHEMBL4539233 Kd 0.23 nM
NS(=O)(=O)c1c(F)c(F)c(Sc2nc3ccccc3s2)c(F)c1F CHEMBL2333411 Kd 0.25 nM
Cc1cc(N2CC(C(=O)O)CC2=O)c(Cl)c(C)c1S(N)(=O)=O CHEMBL4452277 Kd 0.25 nM
NC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Sc1ccccc1 CHEMBL4569008 Kd 0.25 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(SC2CCCCC2)cc1Cl CHEMBL4450545 Kd 0.26 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Br)cc1SC1CCCCC1 CHEMBL4446052 Kd 0.28 nM
Cc1cc(S(N)(=O)=O)c(C)cc1N1CC(C(=O)N/N=C/c2ccccc2)CC1=O CHEMBL4444784 Kd 0.29 nM
NC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1SCc1ccccc1 CHEMBL4456084 Kd 0.29 nM
COC(=O)C1CC(=O)N(c2cc(C)c(S(N)(=O)=O)c(C)c2)C1 CHEMBL4441652 Kd 0.3 nM
Cc1cc(N2CC(c3n[nH]c(=S)n3-c3ccccc3)CC2=O)cc(C)c1S(N)(=O)=O CHEMBL4558457 Kd 0.3 nM
COCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1SC1CCCCC1 CHEMBL4450456 Kd 0.3 nM
NS(=O)(=O)c1cc(C(=O)O)c(NC2CCCCCCC2)cc1Cl CHEMBL4160627 Kd 0.33 nM
NC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1S(=O)(=O)CCc1ccccc1 CHEMBL4441818 Kd 0.33 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1S(=O)(=O)C1CCCCC1 CHEMBL4450306 Kd 0.34 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Br)cc1S(=O)(=O)C1CCCCC1 CHEMBL4454599 Kd 0.34 nM
NS(=O)(=O)c1c(F)c(F)c(S(=O)(=O)CCc2ccccc2)c(F)c1F CHEMBL2333407 Kd 0.4 nM
NS(=O)(=O)c1c(F)c(F)c(NCCc2ccc(O)cc2)c(F)c1F CHEMBL2333405 Kd 0.4 nM
NS(=O)(=O)c1c(F)c(F)c(SCc2ccccc2)c(F)c1F CHEMBL2333403 Kd 0.4 nM
COC(=O)C1CC(=O)N(c2cc(C)c(S(N)(=O)=O)cc2C)C1 CHEMBL4465027 Kd 0.4 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1SCc1ccccc1 CHEMBL4444201 Kd 0.4 nM
CNc1c(F)c(S(N)(=O)=O)c(F)c(F)c1S(=O)(=O)CCc1ccccc1 CHEMBL3799577 Kd 0.42 nM
NS(=O)(=O)c1ccc(C(=O)Cn2cnc3ccccc32)cc1 CHEMBL3797385 Kd 0.43 nM
NS(=O)(=O)c1cc(C(=O)NCc2ccccc2)c(SC2CCCCC2)cc1Cl CHEMBL4442511 Kd 0.45 nM
Cc1cc(S(N)(=O)=O)c(C)cc1N1CC(C(=O)O)CC1=O CHEMBL4577083 Kd 0.46 nM
NS(=O)(=O)c1ccc(NC(=O)C2CC(=O)N(c3ccccc3)C2)cc1 CHEMBL4516072 Kd 0.47 nM
NS(=O)(=O)c1ccc(N2CC(C(=O)N/N=C/c3ccccc3)CC2=O)cc1 CHEMBL4474251 Kd 0.48 nM
NS(=O)(=O)c1c(F)c(F)c(NC23CC4CC(CC(C4)C2)C3)c(F)c1F CHEMBL2333397 Kd 0.5 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(SCc2ccccc2)cc1Cl CHEMBL4565224 Kd 0.52 nM
CCCSc1c(F)c(F)c(S(N)(=O)=O)c(F)c1F CHEMBL2333418 Kd 0.53 nM
NS(=O)(=O)c1ccc(C(=O)CSc2ncccn2)cc1 CHEMBL2011156 Kd 0.53 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1S(=O)(=O)c1ccccc1 CHEMBL4583164 Kd 0.53 nM
Cc1cc(C)n(C(=O)C2CC(=O)N(c3cc(C)c(S(N)(=O)=O)c(C)c3)C2)n1 CHEMBL4567916 Kd 0.55 nM
Cc1cc(NC(=O)C2CC(=O)N(c3ccccc3)C2)cc(C)c1S(N)(=O)=O CHEMBL4448119 Kd 0.56 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(SCc2ccccc2)cc1Br CHEMBL4468310 Kd 0.57 nM
COC(=O)C1CC(=O)N(c2ccc(S(N)(=O)=O)cc2)C1 CHEMBL4567746 Kd 0.63 nM
NS(=O)(=O)c1cc(C(=O)NC2CCCCC2)c(SCc2ccccc2)cc1Cl CHEMBL4451503 Kd 0.63 nM
Cc1cc(N2CC(C(=O)O)CC2=O)cc(C)c1S(=O)(=O)Cl CHEMBL4439634 Kd(app) 0.63 nM
NS(=O)(=O)c1cc(C(=O)NCCCO)c(NCc2ccccc2)cc1Cl CHEMBL4170792 Kd 0.64 nM
NS(=O)(=O)c1cc(C(=O)NCc2ccccc2)c(S(=O)(=O)C2CCCCC2)cc1Cl CHEMBL4573963 Kd 0.68 nM
COCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1NC1CCCCC1 CHEMBL4162451 Kd 0.69 nM
Nc1c(F)cc(S(=O)(=O)Nc2nnc(S(N)(=O)=O)s2)cc1Cl CHEMBL71611 Ki 0.7 nM
COCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1NCc1ccccc1 CHEMBL4170371 Kd 0.72 nM
NS(=O)(=O)c1cc(C(=O)NCCCO)c(SC2CCCCC2)cc1Cl CHEMBL4475073 Kd 0.76 nM
NS(=O)(=O)c1cc(C(=O)NCCCO)c(NC2CCCCC2)cc1Cl CHEMBL4165543 Kd 0.77 nM
NS(=O)(=O)c1cc(C(=O)NCc2ccccc2)c(S(=O)(=O)c2ccccc2)cc1Cl CHEMBL4517317 Kd 0.77 nM
NS(=O)(=O)c1ccc(NC(=O)C2CC(=O)N(c3cccc(Br)c3)C2)cc1 CHEMBL4462447 Kd 0.8 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(S(=O)(=O)c2ccccc2)cc1Cl CHEMBL4443095 Kd 0.82 nM
CC(C)(C)Nc1c(F)c(S(N)(=O)=O)c(F)c(F)c1S(=O)(=O)CCc1ccccc1 CHEMBL3798473 Kd 0.83 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(Sc2ccccc2)cc1Cl CHEMBL4553519 Kd 0.9 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Sc1ccccc1 CHEMBL4574321 Kd 0.9 nM
COC(=O)CCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1SC1CCCCC1 CHEMBL4588838 Kd 0.9 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(Sc2ccccc2)cc1Br CHEMBL4593681 Kd 0.9 nM
NS(=O)(=O)c1c(F)c(F)c(N2CCCCC2)c(F)c1F CHEMBL3797893 Kd 0.91 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Br)cc1S(=O)(=O)c1ccccc1 CHEMBL4576689 Kd 0.92 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Br)cc1Sc1ccccc1 CHEMBL4437818 Kd 0.93 nM
NS(=O)(=O)c1cc(C(=O)O)c(Cl)cc1Cl CHEMBL120886 Kd 0.95 nM
Cc1cc(N2CC(C(=O)NN3CC(C(=O)O)CC3=O)CC2=O)cc(C)c1S(N)(=O)=O CHEMBL4590754 Kd 0.99 nM
NS(=O)(=O)c1c(F)c(F)c(Oc2ccccc2)c(F)c1F CHEMBL2333402 Kd 1.0 nM
NS(=O)(=O)c1c(F)c(F)c(S(=O)(=O)CCO)c(NCc2ccccc2)c1F CHEMBL4085190 Kd 1.0 nM
NS(=O)(=O)c1c(F)c(F)c(SCCO)c(F)c1NC1CCCCCCC1 CHEMBL3359179 Kd 1.0 nM
COC(=O)CCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1SCc1ccccc1 CHEMBL4572161 Kd 1.0 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Br)cc1SCc1ccccc1 CHEMBL4436290 Kd 1.1 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(S(=O)(=O)C2CCCCC2)cc1Br CHEMBL4582964 Kd 1.1 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(NC2CCCCC2)cc1Cl CHEMBL4176828 Kd 1.2 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1NCc1ccccc1 CHEMBL4163518 Kd 1.2 nM
NS(=O)(=O)c1cc(C(=O)NCc2ccccc2)c(NCc2ccccc2)cc1Cl CHEMBL4176862 Kd 1.2 nM
Cc1cc(N2CC(C(=O)O)CC2=O)cc(C)c1S(N)(=O)=O CHEMBL4439909 Kd 1.2 nM
Cc1cc(C)n(NC(=O)C2CC(=O)N(c3cc(C)c(S(N)(=O)=O)c(C)c3)C2)n1 CHEMBL4449149 Kd 1.2 nM
NS(=O)(=O)c1cc(C(=O)NC2CCCCC2)c(SC2CCCCC2)cc1Cl CHEMBL4551069 Kd 1.2 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c([S+]([O-])c2ccccc2)cc1Br CHEMBL4566236 Kd 1.2 nM
NS(=O)(=O)c1cc(C(=O)NCCCC(=O)O)c(SC2CCCCC2)cc1Cl CHEMBL4513684 Kd 1.2 nM
CCCc1cnc(SCC(=O)c2ccc(S(N)(=O)=O)c(Cl)c2)nc1 CHEMBL2443190 Kd 1.25 nM
NS(=O)(=O)c1cc(C(=O)O)c(Br)cc1Br CHEMBL4165127 Kd 1.3 nM
COCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Sc1ccccc1 CHEMBL4470832 Kd 1.3 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(S(=O)(=O)C2CCCCC2)cc1Cl CHEMBL4459385 Kd 1.3 nM
NS(=O)(=O)c1cc(C(=O)NCc2ccccc2)c(Sc2ccccc2)cc1Cl CHEMBL4562296 Kd 1.4 nM
NS(=O)(=O)c1c(F)c(F)c(Sc2ccccc2)c(F)c1F CHEMBL2333815 Kd 1.5 nM
NS(=O)(=O)c1cc(C(=O)NCCCO)c(Sc2ccccc2)cc1Cl CHEMBL4475496 Kd 1.6 nM
COCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1S(=O)(=O)c1ccccc1 CHEMBL4592616 Kd 1.7 nM
CCCCc1cnc(SCC(=O)c2ccc(S(N)(=O)=O)c(Cl)c2)nc1 CHEMBL2443192 Kd 1.82 nM
Cc1cc(S(N)(=O)=O)c(C)cc1N1CC(C(=O)NN)CC1=O CHEMBL4454574 Kd 1.9 nM
NS(=O)(=O)c1ccc(Nc2ncnc(Cl)c2[N+](=O)[O-])cc1 CHEMBL1233722 Kd 2.0 nM
NS(=O)(=O)c1c(F)c(F)c(Sc2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)c(F)c1F CHEMBL2333399 Kd 2.0 nM
NS(=O)(=O)c1c(F)c(F)c(S(=O)(=O)CCO)c(NC2CCCCCCC2)c1F CHEMBL3359181 Kd 2.0 nM
CCc1cnc(SCC(=O)c2ccc(S(N)(=O)=O)c(Cl)c2)nc1 CHEMBL2443206 Kd 2.08 nM
NS(=O)(=O)c1c(F)c(F)c(N/N=C/c2ccccc2)c(F)c1F CHEMBL2333415 Kd 2.2 nM
CCCS(=O)(=O)c1c(F)c(F)c(S(N)(=O)=O)c(F)c1NC1CCCCCCC1 CHEMBL3798303 Kd 2.2 nM
NS(=O)(=O)c1ccc(NC(=O)C2CC(=O)N(c3ccc(Br)cc3)C2)cc1 CHEMBL4570038 Kd 2.2 nM
NS(=O)(=O)c1cc(C(=O)NCCCO)c(S(=O)(=O)C2CCCCC2)cc1Cl CHEMBL4558287 Kd 2.2 nM
NS(=O)(=O)c1cccc(C(=O)Cn2cnc3ccccc32)c1 CHEMBL3799296 Kd 2.3 nM
COCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1S(=O)(=O)C1CCCCC1 CHEMBL4579465 Kd 2.4 nM
COC(=O)CCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1S(=O)(=O)C1CCCCC1 CHEMBL4514121 Kd 2.4 nM
NS(=O)(=O)c1c(F)c(F)c(SC2=S=Nn3c2nc2ccccc23)c(F)c1F CHEMBL2333398 Kd 2.5 nM
Cc1cc(C)nc(Sc2c(F)c(F)c(S(N)(=O)=O)c(F)c2F)n1 CHEMBL2333410 Kd 2.5 nM
Cc1cc(N2CC(C(=O)N/N=C/c3ccc([N+](=O)[O-])cc3)CC2=O)cc(C)c1S(N)(=O)=O CHEMBL4560953 Kd 2.5 nM
NS(=O)(=O)c1cc(C(=O)NC2CCCCC2)c(Cl)cc1Cl CHEMBL4173501 Kd 2.6 nM
COC(=O)CCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Sc1ccccc1 CHEMBL4465972 Kd 2.6 nM
NS(=O)(=O)c1cc(C(=O)NC2CCCCC2)c(S(=O)(=O)C2CCCCC2)cc1Cl CHEMBL4469236 Kd 2.7 nM
CC(=O)OCCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Sc1ccccc1 CHEMBL4565560 Kd 3.0 nM
NS(=O)(=O)c1cc(C(=O)NCCCC(=O)O)c(SCc2ccccc2)cc1Cl CHEMBL4445515 Kd 3.0 nM
COc1ccc(/C=N/NC(=O)C2CC(=O)N(c3cc(C)c(S(N)(=O)=O)c(C)c3)C2)cc1 CHEMBL4558235 Kd 3.1 nM
NS(=O)(=O)c1cc(C(=O)NC2CCCCC2)c(Sc2ccccc2)cc1Cl CHEMBL4573894 Kd 3.2 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Br)cc1SCCO CHEMBL4521683 Kd 3.2 nM
NS(=O)(=O)c1cc(C(=O)NCCCO)c(S(=O)(=O)c2ccccc2)cc1Cl CHEMBL4463844 Kd 3.2 nM
NS(=O)(=O)c1cc(C(=O)NC2CCCCC2)c(S(=O)(=O)c2ccccc2)cc1Cl CHEMBL4466735 Kd 3.2 nM
Cc1cc(C)c(CSc2c(F)c(F)c(S(N)(=O)=O)c(F)c2F)c(C)c1 CHEMBL2333409 Kd 3.3 nM
NS(=O)(=O)c1c(F)c(F)c(S(=O)(=O)c2ccccc2)c(F)c1F CHEMBL2333816 Kd 3.3 nM
Cc1cc(N2CC(C(=O)N/N=C/c3ccccc3)CC2=O)cc(C)c1S(N)(=O)=O CHEMBL4474833 Kd 3.3 nM
NS(=O)(=O)c1cccc(C(=O)CSc2ncccn2)c1 CHEMBL2443189 Kd 4.0 nM
NS(=O)(=O)c1cc(C(=O)NC2CCCCC2)c(SCCO)cc1Cl CHEMBL4464996 Kd 4.0 nM
CC1Cc2ccccc2N1NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 CHEMBL406 Kd 4.11 nM
NS(=O)(=O)c1cc(C(=O)Cn2cnc3ccccc32)c(SCCc2ccccc2)cc1Cl CHEMBL4214894 Kd 4.17 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Br)cc1Br CHEMBL4166643 Kd 4.2 nM
NNC(=O)C1CC(=O)N(c2ccc(S(N)(=O)=O)cc2)C1 CHEMBL4593434 Kd 4.4 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Br)cc1NC1CCCCC1 CHEMBL4177268 Kd 4.5 nM
NS(=O)(=O)c1cc(C(=O)NCc2ccccc2)c(Cl)cc1Cl CHEMBL4165570 Kd 4.7 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(Br)cc1Br CHEMBL4168997 Kd 4.7 nM
Cc1cc(NCC(CC(=O)O)c2n[nH]c(=S)n2-c2ccccc2)cc(C)c1S(N)(=O)=O CHEMBL4465434 Kd 4.8 nM
NS(=O)(=O)c1c(F)c(F)c(NCc2ccccc2)c(F)c1F CHEMBL2333404 Kd 5.0 nM
CC(C)(C)c1cc(=O)[nH]c(SCC(=O)c2ccc(S(N)(=O)=O)c(Cl)c2)n1 CHEMBL2443200 Kd 5.0 nM
Cc1cc(N2CC(C(=O)N/N=C/c3ccc(Br)cc3)CC2=O)cc(C)c1S(N)(=O)=O CHEMBL4443078 Kd 5.0 nM
NS(=O)(=O)c1cc(C(=O)CSc2ncccn2)ccc1Cl CHEMBL2011155 Kd 5.6 nM
NS(=O)(=O)c1cc(C(=O)Nn2cnc3ccccc32)c(SC2CCCCC2)cc1Cl CHEMBL4205449 Kd 5.68 nM
CCc1nc2ccccc2n1CC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 CHEMBL1272243 Kd 5.68 nM
Cc1nc2ccccc2n1CC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 CHEMBL1272188 Kd 5.68 nM
CC(=O)Nc1nnc(S(N)(=O)=O)s1 CHEMBL20 Ki 5.7 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Cl CHEMBL4160149 Kd 5.7 nM
NC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Cl CHEMBL4175740 Kd 5.8 nM
NS(=O)(=O)c1cc(C(=O)NCCCC(=O)O)c(Sc2ccccc2)cc1Cl CHEMBL4584546 Kd 6.0 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(S(=O)(=O)Cc2ccccc2)cc1Br CHEMBL4513913 Kd 6.1 nM
NS(=O)(=O)c1cc(C(=O)Cn2ccnc2-c2ccccc2)ccc1Cl CHEMBL4204892 Kd 6.45 nM
NS(=O)(=O)c1c(F)c(F)c(SCC(=O)O)c(F)c1F CHEMBL2333419 Kd 6.7 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(S(=O)(=O)Cc2ccccc2)cc1Cl CHEMBL4441901 Kd 7.0 nM
COC(=O)CCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Cl CHEMBL4165896 Kd 7.1 nM
NS(=O)(=O)c1cc(C(=O)CN2CCCc3ccccc32)ccc1Cl CHEMBL4203615 Kd 7.47 nM
NS(=O)(=O)c1cc(C(=O)NCCCC(=O)O)c(Cl)cc1Cl CHEMBL4168586 Kd 7.6 nM
NS(=O)(=O)c1cc(C(=O)NCCO)c(Cl)cc1Cl CHEMBL4172331 Kd 7.9 nM
Cc1cc(C)nc(SCC(=O)c2ccc(S(N)(=O)=O)c(Cl)c2)n1 CHEMBL2443204 Kd 8.1 nM
COc1ccc(CNc2c(F)c(F)c(F)c(F)c2S(N)(=O)=O)cc1 CHEMBL3799945 Kd 8.7 nM
NS(=O)(=O)c1cc(C(=O)CN2CCc3ccccc32)ccc1Cl CHEMBL4215863 Kd 8.87 nM
CCc1nccn1CC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 CHEMBL4208414 Kd 8.87 nM
NS(=O)(=O)c1cc(C(=O)NCCCO)c(Cl)cc1Cl CHEMBL4173471 Kd 8.9 nM
NS(=O)(=O)c1cc(C(=O)Cn2cnc3ccccc32)ccc1Cl CHEMBL1272187 Kd 9.46 nM
COCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Cl CHEMBL4166964 Kd 10.0 nM
Cc1cc2ncn(CC(=O)c3ccc(Cl)c(S(N)(=O)=O)c3)c2cc1C CHEMBL4205044 Kd 10.9 nM
CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 CHEMBL220491 Ki 11.0 nM
Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL78755 Ki 11.0 nM
NS(=O)(=O)c1cc(C(=O)Cn2ccnc2)c(Cl)cc1Cl CHEMBL4211504 Kd 11.4 nM
Cc1nc(SCC(=O)c2ccc(S(N)(=O)=O)cc2)[nH]c(=O)c1Cc1ccccc1 CHEMBL2010990 Kd 13.0 nM
CCOc1ccc2nc(S(N)(=O)=O)sc2c1 CHEMBL18 Kd 13.0 nM
NS(=O)(=O)c1cc(C(=O)Cn2c(Cc3ccccc3)nc3ccccc32)ccc1Cl CHEMBL1272242 Kd 13.0 nM
NS(=O)(=O)c1c(F)c(F)c(NCCCCCC(=O)O)c(F)c1F CHEMBL2333814 Kd 14.0 nM
CC(=O)OCCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1Cl CHEMBL4162133 Kd 14.0 nM
Cc1cc(N2CC(C(=O)NN)CC2=O)cc(C)c1S(N)(=O)=O CHEMBL4449430 Kd 15.0 nM
NS(=O)(=O)c1cccc(-c2nnc(-c3ccc(Cl)cc3Cl)o2)c1 CHEMBL4754146 Ki 15.4 nM
NS(=O)(=O)c1cccc(-c2nnc(-c3ccc([N+](=O)[O-])cc3)o2)c1 CHEMBL4788629 Ki 16.2 nM
NS(=O)(=O)c1cccc(-c2nnc(-c3ccc(Cl)cc3)o2)c1 CHEMBL4460034 Ki 16.4 nM
NS(=O)(=O)c1cc(C(=O)N2CCOCC2)c(Cl)cc1Cl CHEMBL4173814 Kd 17.0 nM
COC(=O)CCCNC(=O)c1cc(S(N)(=O)=O)c(Cl)cc1S(=O)(=O)Cc1ccccc1 CHEMBL4472400 Kd 17.0 nM
N#Cc1ccc(-c2nnc(-c3cccc(S(N)(=O)=O)c3)o2)cc1 CHEMBL4755773 Ki 17.0 nM
NS(=O)(=O)c1ccc(N2CCN(c3ccc(F)cc3F)C2=O)cc1 CHEMBL4799997 Ki 17.0 nM
CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 CHEMBL218490 Ki 18.0 nM
NS(=O)(=O)c1cc(C(=O)NC2CCCCC2)c([S+]([O-])Cc2ccccc2)cc1Cl CHEMBL4538502 Kd 18.0 nM
NS(=O)(=O)c1cc(C(=O)Cn2ccnc2)ccc1Cl CHEMBL4204729 Kd 18.2 nM
NS(=O)(=O)c1cccc(-c2nnc(-c3cccs3)o2)c1 CHEMBL4791033 Ki 18.4 nM
CC(=O)/N=c1/sc(S(N)(=O)=O)nn1C CHEMBL19 Ki 19.0 nM
CCCCc1cnc(SCC(=O)c2ccc(S(N)(=O)=O)cc2)nc1 CHEMBL2011154 Kd 19.0 nM
NS(=O)(=O)c1cccc(-c2nnc(-c3cccc([N+](=O)[O-])c3)o2)c1 CHEMBL4787403 Ki 19.1 nM
NS(=O)(=O)c1ccc(CNc2nc[nH]c(=O)c2[N+](=O)[O-])cc1 CHEMBL1233732 Kd 20.0 nM
NS(=O)(=O)C(F)(F)F CHEMBL67511 Kd 20.0 nM
CCCc1cnc(SCC(=O)c2ccc(S(N)(=O)=O)cc2)nc1 CHEMBL2011153 Kd 20.0 nM
NS(=O)(=O)c1c(F)c(F)c(SCCC(=O)O)c(F)c1F CHEMBL2333420 Kd 20.0 nM
NS(=O)(=O)c1c(F)c(F)cc(F)c1F CHEMBL2333412 Kd 20.0 nM
Cc1cc(C)[n+](CCc2ccc(S(N)(=O)=O)cc2)c(C)c1 CHEMBL352535 Ki 21.0 nM
NS(=O)(=O)c1cc(Cl)c(Cl)c(S(N)(=O)=O)c1 CHEMBL17 Ki 23.0 nM
NS(=O)(=O)c1cc(C(=O)Nn2cnc3ccccc32)c(Sc2ccccc2)cc1Cl CHEMBL4218335 Kd 23.6 nM
NS(=O)(=O)c1cc(C(=O)NC2CCCCC2)c(S(=O)(=O)Cc2ccccc2)cc1Cl CHEMBL4529297 Kd 24.0 nM
CC(C)(C)c1cc(=O)[nH]c(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)n1 CHEMBL2010993 Kd 25.0 nM
NS(=O)(=O)c1c(F)c(F)c(N2CCOCC2)c(F)c1F CHEMBL2333408 Kd 25.0 nM
Cc1nc(SCC(=O)c2ccc(S(N)(=O)=O)c(Cl)c2)[nH]c(=O)c1Cc1ccccc1 CHEMBL2443196 Kd 25.0 nM
CSc1nc(Cl)c(C=O)c(NCc2ccc(S(N)(=O)=O)cc2)n1 CHEMBL1233735 Kd 28.0 nM
NS(=O)(=O)c1cc(C(=O)NC2CCCCC2)c(S(=O)(=O)CCO)cc1Cl CHEMBL4549561 Kd 28.0 nM
CCc1cnc(SCC(=O)c2ccc(S(N)(=O)=O)cc2)nc1 CHEMBL2011000 Kd 28.6 nM
NS(=O)(=O)c1c(F)c(F)c(S(=O)(=O)CCO)c(F)c1F CHEMBL2333417 Kd 29.0 nM
NS(=O)(=O)c1cccc(-c2nnc(-c3ccccc3)o2)c1 CHEMBL4762313 Ki 30.9 nM
NS(=O)(=O)c1cc(C(=O)Cn2cnc3ccccc32)c(Cl)cc1Cl CHEMBL4207063 Kd 31.0 nM
COc1ccc(OC)c(-c2nnc(-c3cccc(S(N)(=O)=O)c3)o2)c1 CHEMBL4747504 Ki 31.4 nM
Nc1ccc(S(N)(=O)=O)cc1 CHEMBL21 Ki 32.0 nM
CSc1nc(Cl)c(C=O)c(NCCc2ccc(S(N)(=O)=O)cc2)n1 CHEMBL1271467 Kd 33.0 nM
CCCSc1c(F)c(F)c(S(N)(=O)=O)c(NC2CCCCCCC2)c1F CHEMBL3797835 Kd 33.0 nM
Cc1cc(=O)[nH]c(SCC(=O)c2ccc(S(N)(=O)=O)c(Cl)c2)n1 CHEMBL2443194 Kd 33.3 nM
COc1ccc(-c2nnc(-c3cccc(S(N)(=O)=O)c3)o2)c(OC)c1 CHEMBL4798581 Ki 36.7 nM
Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(S(N)(=O)=O)nc2)cc1 CHEMBL3099282 Ki 38.0 nM
COc1cc(-c2nnc(-c3cccc(S(N)(=O)=O)c3)o2)cc(OC)c1OC CHEMBL4743714 Ki 38.5 nM
NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F CHEMBL2333413 Kd 40.0 nM
Cc1nc(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)[nH]c(=O)c1Cc1ccccc1 CHEMBL2010989 Kd 42.0 nM
NS(=O)(=O)c1cc(C(=O)Nn2cnc3ccccc32)c(Cl)cc1Cl CHEMBL4207577 Kd 43.4 nM
NS(=O)(=O)c1cc(C(=O)NCCCC(=O)O)c(S(=O)(=O)Cc2ccccc2)cc1Cl CHEMBL4472135 Kd 45.0 nM
CC1(C)O[C@@H]2[C@@H](CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@@H]23)O1 CHEMBL220492 Ki 47.0 nM
Cc1cc2ncn(CC(=O)c3cc(S(N)(=O)=O)c(Cl)cc3Cl)c2cc1C CHEMBL4210750 Kd 47.2 nM
CCCSc1ccc(S(N)(=O)=O)cc1 CHEMBL2333400 Kd 50.0 nM
CCCc1cc(=O)[nH]c(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)n1 CHEMBL2010991 Kd 55.6 nM
Cc1cc(C)o/c(=N/O)c1 CHEMBL1956578 Ki 59.0 nM
NS(=O)(=O)c1ccc(CNc2nc(Cl)nc(NCC(=O)O)n2)cc1 CHEMBL191045 Ki 62.0 nM
CCCc1cc(=O)[nH]c(SCC(=O)c2ccc(S(N)(=O)=O)cc2)n1 CHEMBL2010992 Kd 62.5 nM
O=c1ccc2ccccc2[nH]1 CHEMBL186422 Ki 65.0 nM
CC1(C)O[C@H]2[C@H](O)CN(CCCCCCn3cc(CNc4ccc(S(N)(=O)=O)cc4)nn3)C[C@H]2O1 CHEMBL4643051 Ki 65.3 nM
CCCCc1cnc(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)nc1 CHEMBL2010807 Kd 66.7 nM
COc1ncnc(NCc2ccc(S(N)(=O)=O)cc2)c1[N+](=O)[O-] CHEMBL1233725 Kd 67.0 nM
NS(=O)(=O)c1ccc(C(=O)CSc2ccccc2)cc1 CHEMBL2011158 Kd 67.0 nM
CCCc1cnc(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)nc1 CHEMBL2011152 Kd 67.0 nM
NS(=O)(=O)c1ccc(CCNc2nc(Cl)nc(NCC(=O)O)n2)cc1 CHEMBL189526 Ki 68.0 nM
NS(=O)(=O)c1cc(C(=O)N2CCOCC2)c(Sc2ccccc2)cc1Cl CHEMBL4579206 Kd 69.0 nM
CCOC(=O)c1cnc(SCC(=O)c2ccc(S(N)(=O)=O)c(Cl)c2)[nH]c1=O CHEMBL2443202 Kd 76.9 nM
Nc1nnc(S(N)(=O)=O)s1 CHEMBL265674 Ki 79.0 nM
Cc1cc(C)nc(SCC(=O)c2ccc(S(N)(=O)=O)cc2)n1 CHEMBL2010998 Kd 83.0 nM
CCCc1cc(=O)[nH]c(SCC(=O)c2ccc(S(N)(=O)=O)c(Cl)c2)n1 CHEMBL2443198 Kd 83.3 nM
NS(=O)(=O)c1ccc(C[Se]c2ccc(NC(=O)CN3C(=O)NC4(CCCCCC4)C3=O)cc2)cc1 CHEMBL4464229 Ki 88.4 nM
CSc1nc(Cl)c(C#N)c(Nc2ccc(S(N)(=O)=O)cc2)n1 CHEMBL1272233 Kd 91.0 nM
O/N=c1/ccc2ccccc2o1 CHEMBL1956579 Ki 94.0 nM
Cc1cc2ncn(CC(=O)c3cc(S(N)(=O)=O)c(Cl)cc3Sc3ccccc3)c2cc1C CHEMBL4207242 Kd 94.6 nM
Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 CHEMBL118 Ki 98.0 nM
CSc1nc(Cl)c(C#N)c(NCCc2ccc(S(N)(=O)=O)cc2)n1 CHEMBL1272286 Kd 100.0 nM
NS(=O)(=O)c1cc(C(=O)CSc2nc3cc4c(cc3[nH]2)OCCO4)ccc1Cl CHEMBL1232443 Kd 100.0 nM
NS(=O)(=O)c1cc(C(=O)CSc2nc3cc(Br)ccc3[nH]2)ccc1Cl CHEMBL1271638 Kd 100.0 nM
NS(=O)(=O)c1cc(C(=O)CSc2nc3cnc4ccccc4c3[nH]2)ccc1Cl CHEMBL1271639 Kd 100.0 nM
NS(=O)(=O)c1cc(C(=O)CSc2nc3ccccc3[nH]2)ccc1Cl CHEMBL1271585 Kd 100.0 nM
Cc1cc(=O)[nH]c(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)n1 CHEMBL2010987 Kd 100.0 nM
CCc1cnc(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)nc1 CHEMBL2010999 Kd 110.0 nM
CCCCNC(=O)c1cc(S(N)(=O)=O)c(Br)cc1NCc1ccccc1 CHEMBL4170058 Kd 110.0 nM
NS(=O)(=O)c1nnc(NC(=O)C23CC4CC(CC(C4)C2)C3)s1 CHEMBL1209038 Ki 118.0 nM
NS(=O)(=O)c1ccc(NC(=O)Cc2cccs2)cc1 CHEMBL573127 Ki 125.0 nM
CCOC(=O)c1cnc(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)[nH]c1=O CHEMBL2010995 Kd 125.0 nM
COc1ncnc(NCCc2ccc(S(N)(=O)=O)cc2)c1[N+](=O)[O-] CHEMBL1233768 Kd 130.0 nM
CSc1nc(Cl)c(C#N)c(NCc2ccc(S(N)(=O)=O)cc2)n1 CHEMBL1272285 Kd 140.0 nM
NNc1c(F)c(F)c(S(N)(=O)=O)c(F)c1F CHEMBL2333414 Kd 140.0 nM
NS(=O)(=O)c1nnc(NC(=O)CC23CC4CC(CC(C4)C2)C3)s1 CHEMBL1209039 Ki 147.0 nM
Nc1ccc(S(N)(=O)=O)nc1 CHEMBL3099281 Ki 155.0 nM
CC(C)(C)c1cc(=O)[nH]c(SCC(=O)c2cccc(S(N)(=O)=O)c2)n1 CHEMBL2443201 Kd 167.0 nM
NC(N)=Nc1nc(CSCC/C(N)=N/S(N)(=O)=O)cs1 CHEMBL902 Ki 171.5 nM
CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1C21c2ccccc2C(=O)N1c1cccc(S(N)(=O)=O)c1 CHEMBL1822700 Ki 236.0 nM
NS(=O)(=O)c1cc(C(=O)CSc2ccccc2)ccc1Cl CHEMBL2011157 Kd 250.0 nM
CCCCc1cnc(SCC(=O)c2cccc(S(N)(=O)=O)c2)nc1 CHEMBL2443193 Kd 278.0 nM
CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1C21c2ccccc2C(=O)N1c1ccc(S(N)(=O)=O)cc1 CHEMBL1822699 Ki 280.0 nM
CCOC(=O)c1cnc(SCC(=O)c2ccc(S(N)(=O)=O)cc2)[nH]c1=O CHEMBL2010996 Kd 286.0 nM
NS(=O)(=O)c1ccc(SCCc2ccccc2)cc1 CHEMBL2333401 Kd 290.0 nM
NS(=O)(=O)c1cc(C(=O)Cn2c(CO)nc3ccccc32)ccc1Cl CHEMBL1272189 Kd 300.0 nM
NS(=O)(=O)c1ccc(CNc2ncnc(NCc3ccccc3)c2[N+](=O)[O-])cc1 CHEMBL1233727 Kd 330.0 nM
Cc1cc(C)nc(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)n1 CHEMBL2010997 Kd 330.0 nM
CCCc1cnc(SCC(=O)c2cccc(S(N)(=O)=O)c2)nc1 CHEMBL2443191 Kd 333.0 nM
Cc1cc(=O)[nH]c(SCC(=O)c2ccc(S(N)(=O)=O)cc2)n1 CHEMBL2010988 Kd 357.0 nM
CCCCc1nc2ccccc2n1CC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 CHEMBL1272298 Kd 400.0 nM
CC(C)c1nc2ccccc2n1CC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 CHEMBL1271477 Kd 400.0 nM
Cc1onc(-c2ccccc2)c1-c1ccc(S(N)(=O)=O)cc1 CHEMBL865 Ki 425.0 nM
CC1(C)O[C@H]2[C@H](O)[C@H]([C@H]3[C@H](O)[C@H]4OC[C@@H](O4)[C@H]3O)N(CCCCCCn3cc(CNc4ccc(S(N)(=O)=O)cc4)nn3)C[C@H]2O1 CHEMBL4649348 Ki 429.1 nM
NS(=O)(=O)Cc1noc2ccccc12 CHEMBL750 Ki 430.0 nM
NS(=O)(=O)c1ccc(NC(=O)Cc2cccs2)c(F)c1 CHEMBL574246 Ki 437.0 nM
CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1C21c2ccccc2C(=O)N1CCc1ccc(S(N)(=O)=O)cc1 CHEMBL1822702 Ki 463.0 nM
NS(=O)(=O)c1ccc(CCNc2nc(F)nc(F)n2)cc1 CHEMBL2443314 Ki 470.0 nM
NS(=O)(=O)c1cc(C(=O)Cn2cnc(-c3ccccc3)c2-c2ccccc2)ccc1Cl CHEMBL4216585 Kd 489.0 nM
NS(=O)(=O)c1ccc(Nc2ncnc(NCc3ccccc3)c2[N+](=O)[O-])cc1 CHEMBL1271521 Kd 500.0 nM
NS(=O)(=O)c1ccc(CCNc2ncnc(NCc3ccccc3)c2[N+](=O)[O-])cc1 CHEMBL1271572 Kd 500.0 nM
CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1C21c2ccccc2C(=O)N1Cc1ccc(S(N)(=O)=O)cc1 CHEMBL1822701 Ki 515.0 nM
CCc1cnc(SCC(=O)c2cccc(S(N)(=O)=O)c2)nc1 CHEMBL2443207 Kd 556.0 nM
COC(=O)CNc1nc(F)nc(NCCc2ccc(S(N)(=O)=O)cc2)n1 CHEMBL2443317 Ki 602.0 nM
NS(=O)(=O)c1ccc(-n2ncc3c2-c2ccc(C(F)(F)F)cc2SC3)cc1 CHEMBL2179306 Ki 714.0 nM
CNc1nc(F)nc(Nc2ccc(S(N)(=O)=O)cc2)n1 CHEMBL2443316 Ki 735.0 nM
CC1CCCC2(C1)NC(=O)N(CC(=O)Nc1ccc([Se]Cc3ccc(S(N)(=O)=O)cc3)cc1)C2=O CHEMBL4448793 Ki 767.0 nM
NS(=O)(=O)c1ccc(NC(=O)CN2C(=O)NC3(CCCCC3)C2=O)cc1 CHEMBL4541654 Ki 808.5 nM
CCCc1cc(=O)[nH]c(SCC(=O)c2cccc(S(N)(=O)=O)c2)n1 CHEMBL2443199 Kd 833.0 nM
CNc1nc(NC)nc(Nc2ccc(S(N)(=O)=O)cc2)n1 CHEMBL186716 Ki 921.0 nM
COc1ccc2c(c1)SCc1cnn(-c3ccc(S(N)(=O)=O)cc3)c1-2 CHEMBL2179308 Ki 938.0 nM
NS(=O)(=O)c1ccc(SCCO)cc1 CHEMBL106848 Kd 1000.0 nM
Cc1cc(C)nc(SCC(=O)c2cccc(S(N)(=O)=O)c2)n1 CHEMBL2443205 Kd 1000.0 nM