COc1ccccc1-n1nc(C2CC(C)(C)OC(C)(C)C2)cc1-c1ccc(Cl)cc1 CHEMBL4279774 IC50 1.0 nM
COc1ccccc1-n1nc(C2CC(C)(C)OC(C)(C)C2)cc1-c1ccc(C#N)cc1 CHEMBL4292697 IC50 1.0 nM
CCN(CC)c1ccccc1-n1nc(C2CC(C)(C)OC(C)(C)C2)cc1-c1ccc(Cl)cc1 CHEMBL4288564 IC50 1.0 nM
COc1ccccc1-n1nc(C2CCOC(C)(C)C2)cc1-c1ccc(Cl)cc1 CHEMBL4290426 IC50 2.0 nM
COc1ccccc1-n1nc(C2C[C@H](C)O[C@@H](C)C2)cc1-c1ccc(Cl)cc1 CHEMBL4289288 IC50 2.0 nM
CCOc1ccc(-c2cc(C3CC(C)(C)OC(C)(C)C3)nn2-c2ccccc2OC)cc1 CHEMBL4282095 IC50 2.0 nM
COc1ccccc1-n1nc([C@H]2C[C@@H](C)O[C@@H](C)C2)cc1-c1ccc(Cl)cc1 CHEMBL4278633 IC50 3.0 nM
COc1ccccc1-n1nc(C2=CC(C)(C)OC(C)(C)C2)cc1-c1ccc(Cl)cc1 CHEMBL4293756 IC50 3.0 nM
CCOc1ccc(-c2cc(C3CC(C)(C)OC(C)(C)C3)nn2-c2ccccc2OC)cn1 CHEMBL4283590 IC50 5.0 nM
COc1ccccc1-n1nc(C2CC(C)(C)OC(C)(C)C2)cc1-c1csc(Cl)c1 CHEMBL4277584 IC50 6.0 nM
COc1ccccc1-n1nc(C2CC(C)(C)OC(C)(C)C2)cc1-c1ccc(C)nc1 CHEMBL4294178 IC50 6.0 nM
COc1ccccc1-n1nc([C@@H]2CCO[C@H](C(C)C)C2)cc1-c1ccc(Cl)cc1 CHEMBL4285527 IC50 7.0 nM
CC1(C)CC(c2cc(-c3ccc(Cl)cc3)n(-c3ccncc3)n2)CC(C)(C)O1 CHEMBL4291986 IC50 7.0 nM
COc1ccccc1-n1nc(C2CC(C)(C)OC(C)(C)C2)cc1-c1ccnc(Cl)c1 CHEMBL4280661 IC50 11.0 nM
CC1(C)CC(c2cc(-c3ccc(Cl)cc3)n(-c3ccccn3)n2)CC(C)(C)O1 CHEMBL4284117 IC50 12.0 nM
C[C@@H](O)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@@H]4C[C@@H](O)CN4C(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC[C@H](NC(=O)[C@H](CSSC[C@@H](C(=O)N[C@@H](Cc4ccc(O)cc4)C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC1=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](CO)NC3=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N2 CHEMBL1651027 IC50 20.0 nM
COc1ccccc1-n1nc([C@@H]2CCO[C@@H](C(C)C)C2)cc1-c1ccc(Cl)cc1 CHEMBL4285877 IC50 20.0 nM
CS(=O)(=O)c1ccc(C(=O)N2CCC(N(C3CC3)S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)c(C(F)(F)F)c1 CHEMBL3092205 IC50 21.0 nM
CSCC[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@H]3CSSC[C@@H](C(N)=O)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC3=O)[C@@H](C)O)NC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N2)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O CHEMBL4292404 IC50 22.0 nM
CS(=O)(=O)c1cc(C(F)(F)F)ccc1C(=O)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 CHEMBL3092201 IC50 27.0 nM
COc1ccccc1-n1nc(C2CCOCC2)cc1-c1ccc(Cl)cc1 CHEMBL4292985 IC50 30.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)Cc1ccc(C(C)(C)C)cc1 CHEMBL304309 IC50 36.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)Cc1ccc(C(C)(C)C)cc1 CHEMBL299749 IC50 40.0 nM
C[C@H]1[C@H](N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CN1C(=O)c1ccc(S(C)(=O)=O)cc1Cl CHEMBL3092218 IC50 48.0 nM
CS(=O)(=O)c1ccc(C(=O)N2CCC(N(C3CC3)S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)c(OC(F)(F)F)c1 CHEMBL3092206 IC50 48.0 nM
COc1cccc(OC)c1CN1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 CHEMBL2180892 IC50 60.0 nM
CS(=O)(=O)c1cc(C(F)(F)F)ccc1C(=O)N1CCC2(CCN(S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)C1 CHEMBL3092220 IC50 72.0 nM
CC(C1CCN(C(=O)c2ccc(S(C)(=O)=O)cc2OC(F)(F)F)CC1)S(=O)(=O)c1cccc(C(F)(F)F)c1 CHEMBL3092223 IC50 88.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N1CCCCC1)N(C)Cc1ccc(C(C)(C)C)cc1 CHEMBL300261 IC50 90.0 nM
CC(C)(C1CCN(C(=O)c2ccc(S(C)(=O)=O)cc2OC(F)(F)F)CC1)S(=O)(=O)c1cccc(C(F)(F)F)c1 CHEMBL3092197 IC50 92.0 nM
CCCCOc1cccc(C(F)(F)CNCC(=O)N(C)C)c1 CHEMBL3978361 Ki 100.0 nM
CCCCCCOc1cccc(C(F)(F)CNCC(=O)N(C)C)c1 CHEMBL3954509 Ki 100.0 nM
CN(C)C(=O)CNCC(F)(F)c1cccc(OCCCC(F)(F)F)c1 CHEMBL3894280 Ki 100.0 nM
COC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)NCc1ccc(Oc2ccccc2)cc1 CHEMBL355833 IC50 120.0 nM
COCC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)NCc1ccc(Oc2ccccc2)cc1 CHEMBL355254 IC50 120.0 nM
O=C(c1ccccc1OC(F)(F)F)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 CHEMBL2180894 IC50 120.0 nM
CCCN(C1CCN(Cc2c(OC)cccc2OC)CC1)S(=O)(=O)c1cccc(C(F)(F)F)c1 CHEMBL2180891 IC50 120.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)Cc1ccc(Br)cc1 CHEMBL430996 IC50 130.0 nM
CC(C)(C)OC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)NCc1ccc(Oc2ccccc2)cc1 CHEMBL74345 IC50 140.0 nM
CC(C)(C)OC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)NC1CCN(c2ccccc2)CC1 CHEMBL76163 IC50 150.0 nM
CC(C)CCN(c1ccc(NCCC(C)(C)C)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC(=O)N2CCCCCC2)CC1 CHEMBL79649 IC50 180.0 nM
CC(C)CCN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC(=O)N2CCCCCC2)CC1 CHEMBL80994 IC50 190.0 nM
Cc1cc(C)cc(-c2cc3cc(C(C)(C)C(=O)NC(C)(C)C)ccc3n2CC(=O)NC(C)(C)C)c1 CHEMBL1643724 IC50 190.0 nM
CS(=O)(=O)c1ccc(F)cc1C(=O)N1CCC2(CCN(S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)C1 CHEMBL3092214 IC50 190.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)C1CCCCC1 CHEMBL422741 IC50 200.0 nM
COCCN1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)NCc1ccc(Oc2ccccc2)cc1 CHEMBL554925 IC50 200.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)C1CCCCC1 CHEMBL423302 IC50 200.0 nM
CCCCOc1cccc(C(F)(F)CNCC(=O)N2CCCC2)c1 CHEMBL3903255 Ki 200.0 nM
O=C(CNCC(F)(F)c1cccc(OCCCC(F)(F)F)c1)N1CCCC1 CHEMBL3977403 Ki 200.0 nM
CCC(C)N1C(=O)CSC1c1cnccc1-c1ccc(Br)cc1 CHEMBL231820 IC50 210.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)Cc1ccc(Cl)cc1 CHEMBL303039 IC50 230.0 nM
CN(C)c1cccc(C(=O)N2CCC(N(C3CC3)S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)c1 CHEMBL2180898 IC50 240.0 nM
CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL468019 Activity 250.0 nM
O=C(Nc1ncc([N+](=O)[O-])s1)C(c1ccccc1)c1ccccc1 CHEMBL468026 Activity 250.0 nM
CC(C)=CCN(CC(C)(C)NC(=O)[C@H](CC(C)C)NC(=O)N1CCCCCC1)c1ccc(OCc2ccccc2)cc1 CHEMBL336328 IC50 260.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC1CCN(Cc2ccccc2)CC1)N(C)Cc1ccc(C(C)(C)C)cc1 CHEMBL52649 IC50 270.0 nM
CS(=O)(=O)c1ccc(C(=O)N2CC(N(C3CC3)S(=O)(=O)c3cccc(C(F)(F)F)c3)C2)c(C(F)(F)F)c1 CHEMBL3092217 IC50 270.0 nM
CCCCN(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C CHEMBL173060 IC50 280.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)Cc1ccc(N(C)C)cc1 CHEMBL68088 IC50 280.0 nM
CC(C)CCN(c1ccc(NCC2CCCCC2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC(=O)N2CCCCCC2)CC1 CHEMBL81861 IC50 290.0 nM
O=C(N[C@@H](CSCC1CCCCC1)C(=O)NCc1ccc(Oc2ccccc2)cc1)[C@@H]1CSCN1 CHEMBL353606 IC50 290.0 nM
CS(=O)(=O)c1ccc(C(=O)N2CCC(N(C3CC3)S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)c(Cl)c1 CHEMBL3092204 IC50 290.0 nM
CC(C)CCN[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C CHEMBL275612 IC50 300.0 nM
O=C(c1ccc(OC(F)(F)F)cc1)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 CHEMBL2180896 IC50 300.0 nM
CCCCOc1cccc(C(F)(F)CNCC(=O)N(CC)CC)c1 CHEMBL3897897 Ki 300.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC1CCN(Cc2ccccc2)CC1)N(C)CC1CCCCC1 CHEMBL402674 IC50 310.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NCCN1CCCCC1)N(C)Cc1ccc(C(C)(C)C)cc1 CHEMBL52699 IC50 310.0 nM
CS(=O)(=O)c1ccc(C(=O)N2CCC3(CCN(S(=O)(=O)c4cccc(C(F)(F)F)c4)CC3)C2)c(C(F)(F)F)c1 CHEMBL3092219 IC50 310.0 nM
CC(C)CCN(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C CHEMBL277085 IC50 320.0 nM
CC(C)CCN1C(C)CCCC1C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)OC(C)(C)C CHEMBL13674 IC50 320.0 nM
CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)OC(C)(C)C CHEMBL135329 IC50 320.0 nM
CC(C)CCN(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C CHEMBL292011 IC50 320.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N1CCCCC1)N(C)CC1CCCCC1 CHEMBL300478 IC50 320.0 nM
CC(C)(C)OC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)NC1CCN(Cc2ccccc2)CC1 CHEMBL73525 IC50 330.0 nM
C=CCOC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)NCc1ccc(Oc2ccccc2)cc1 CHEMBL170698 IC50 330.0 nM
CC(C)=CCN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC(=O)N2CCCCCC2)CC1 CHEMBL311867 IC50 340.0 nM
CS(=O)(=O)c1ccc(Cl)c(C(=O)N2CCC(N(C3CC3)S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)c1 CHEMBL3092202 IC50 340.0 nM
O=C(NCc1ccc(Oc2ccccc2)cc1)[C@H](CSCC1CCCCC1)NC(=O)[C@@H]1CSCN1CCO CHEMBL172384 IC50 350.0 nM
CS(=O)(=O)c1ccc(C(=O)N2CCC(N(C3CC3)S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)c(F)c1 CHEMBL3092203 IC50 350.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)Cc1ccccc1 CHEMBL303609 IC50 360.0 nM
CC(C)COC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)NCc1ccc(Oc2ccccc2)cc1 CHEMBL170618 IC50 360.0 nM
CS(=O)(=O)c1ccc(C(=O)N2CCC(CS(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)c(OC(F)(F)F)c1 CHEMBL3092222 IC50 360.0 nM
CC(C)CCN(C)[C@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C CHEMBL430104 IC50 370.0 nM
CC(C)(C)OC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)N1CCN(Cc2ccccc2)CC1 CHEMBL72446 IC50 370.0 nM
O=C(c1cccc(OC(F)(F)F)c1)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 CHEMBL2180895 IC50 370.0 nM
CS(=O)(=O)c1ccc(F)cc1C(=O)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)C1 CHEMBL3092210 IC50 370.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)CC(C)C CHEMBL369244 IC50 380.0 nM
CC(C)(C)OC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)NCCNCc1ccccc1 CHEMBL308984 IC50 380.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N1CCCCC1)N(C)C1CCCCC1 CHEMBL53176 IC50 380.0 nM
COC(=O)c1cccc(C(=O)N2CCC(N(C3CC3)S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)c1 CHEMBL2180897 IC50 380.0 nM
C[C@@H]1[C@H](N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CN1C(=O)c1cc(F)ccc1S(C)(=O)=O CHEMBL3092212 IC50 380.0 nM
CC(C)N[C@@H](CC(C)(C)C)C(=O)N[C@H]1CC[C@@H]2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)C[C@@H]21 CHEMBL2414787 pIC50 389.05 nM
CC(C)(C)OC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)N1CCN(c2ccccc2)CC1 CHEMBL433125 IC50 390.0 nM
COc1ccc(COC(=O)[C@H](CSCC2CCCCC2)NC(=O)[C@@H]2CSCN2C(=O)OC(C)(C)C)cc1 CHEMBL170453 IC50 390.0 nM
NC(=O)c1ccc(C(=O)N2CCC(N(C3CC3)S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)c(OC(F)(F)F)c1 CHEMBL3092208 IC50 390.0 nM
CC(C)CCN[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)OC(C)(C)C CHEMBL277819 IC50 400.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)CCC(C)(C)C CHEMBL170471 IC50 400.0 nM
CC(C)CCN(c1ccc(NCc2ccccc2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC(=O)N2CCCCCC2)CC1 CHEMBL82536 IC50 400.0 nM
COc1ccc(C(C#N)(CCCN2CCC(NCCOc3ccccc3)CC2)C(C)C)cc1OC CHEMBL190784 IC50 400.0 nM
COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CCc2cc(F)ccc2[C@@H]1C(C)C CHEMBL45816 IC50 416.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N1CCN(Cc2ccccc2)CC1)N(C)CC1CCCCC1 CHEMBL53111 IC50 420.0 nM
CC(CCCN(Cc1ccccc1)Cc1ccccc1)(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1 CHEMBL309614 IC50 430.0 nM
CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N1CCC(N(Cc2ccccc2)c2ccc(OCc3ccccc3)cc2)CC1 CHEMBL135401 IC50 430.0 nM
C[C@H]1[C@H](N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CN1C(=O)c1cc(F)ccc1S(C)(=O)=O CHEMBL3092213 IC50 430.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N1CCN(C)CC1)N(C)Cc1ccc(C(C)(C)C)cc1 CHEMBL53077 IC50 440.0 nM
Cc1ccc(-c2ccncc2[C@H]2SCC(=O)N2CC(C)C)cc1 CHEMBL232849 IC50 440.0 nM
CC(C)C[C@@H](C(=O)N[C@@H]1CC[C@H]2CN(S(=O)(=O)c3cccc(C(F)(F)F)c3)C[C@H]21)N(C)C CHEMBL2414779 IC50 450.0 nM
CS(=O)(=O)c1cc(C#N)ccc1C(=O)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 CHEMBL3092200 IC50 450.0 nM
Oc1c(CN2CCCCCC2)ccc2c1CCN(CCCC(c1ccccc1)c1ccccc1)C2 CHEMBL78017 IC50 460.0 nM
CN(C1CCN(C(=O)c2ccccc2S(C)(=O)=O)CC1)S(=O)(=O)c1cccc(C(F)(F)F)c1 CHEMBL3092215 IC50 460.0 nM
CCN(C1CCN(C(=O)c2ccccc2OC(F)(F)F)CC1)S(=O)(=O)c1cccc(C(F)(F)F)c1 CHEMBL3092216 IC50 470.0 nM
CC(C)=CCN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NCCC(C)C)CC1 CHEMBL135774 IC50 480.0 nM
CC(C)CCN1CCC(C(C)C)CC1C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)OC(C)(C)C CHEMBL13798 IC50 490.0 nM
CC(C)CCN(c1ccc(NCc2ccc(N(C)C)cc2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC(=O)N2CCCCCC2)CC1 CHEMBL81511 IC50 490.0 nM
CC(CCC(O)(c1ccccc1)c1ccccc1)(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1 CHEMBL310428 IC50 490.0 nM
Cc1ccc(-c2ccncc2C2SCC(=O)N2CC(C)C)cc1 CHEMBL245173 IC50 490.0 nM
CCN[C@@H](CC(C)(C)C)C(=O)N[C@H]1CC[C@@H]2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)C[C@@H]21 CHEMBL2414769 IC50 490.0 nM
COc1ccc(CN(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc2ccc(OC(=O)c3ccccc3)cc2)C(=O)NC(C)(C)C)cc1 CHEMBL419805 IC50 500.0 nM
CC(C)(C)OC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)N1CCC(NCc2ccccc2)CC1 CHEMBL306399 IC50 500.0 nM
CC(C)(C)OC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)NCc1ccc(OCc2ccccc2)cc1 CHEMBL170243 IC50 500.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)CC1CCCCC1 CHEMBL50210 IC50 500.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N1CCN(Cc2ccccc2)CC1)N(C)Cc1ccc(C(C)(C)C)cc1 CHEMBL300626 IC50 500.0 nM
CSCC[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CO)NC(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CSSC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N2)NC(=O)[C@H](CSSC[C@@H](C(N)=O)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC3=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O CHEMBL4594214 IC50 500.0 nM
CC(C)CN1C(=O)CSC1c1ccncc1-c1ccc(Br)cc1 CHEMBL389993 IC50 500.0 nM
CN(C)C(=O)CNCC(F)(F)c1cccc(OCc2ccccc2)c1 CHEMBL3897000 Ki 500.0 nM
CC(C)=CCN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC2CCCCC2)CC1 CHEMBL336605 IC50 510.0 nM
C=Cc1ccc(-c2ccncc2C2SCC(=O)N2CC(C)C)cc1 CHEMBL233855 IC50 510.0 nM
CC(C)(C1CCN(C(=O)c2cc(F)ccc2S(C)(=O)=O)CC1)S(=O)(=O)c1cccc(C(F)(F)F)c1 CHEMBL3092198 IC50 510.0 nM
COCCn1c(-c2cc(C)cc(C)c2)cc2cc(C(C)(C)C(=O)NC(C)(C)C)ccc21 CHEMBL1643725 IC50 520.0 nM
COC(OC)C1=C(C(=O)OC/C=C/c2ccccc2)C(c2ccc(Cl)c(Cl)c2)C(C(=O)O)=CN1 CHEMBL2030594 IC50 520.0 nM
CN[C@@H](CC(C)C)C(=O)N[C@@H]1CC[C@H]2CN(S(=O)(=O)c3cccc(C(F)(F)F)c3)C[C@H]21 CHEMBL2414777 IC50 520.0 nM
C=Cc1ccc(-c2cnccc2C2SCC(=O)N2CC(C)C)cc1 CHEMBL234915 IC50 530.0 nM
Cc1cc(C)cc(-c2cc3cc(C(C)(C)C(=O)NC(C)(C)C)ccc3n2Cc2c(C)noc2C)c1 CHEMBL1643726 IC50 540.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)Cc1ccccc1Cl CHEMBL67766 IC50 560.0 nM
O=C1CSC(c2cccnc2-c2ccc(C(F)(F)F)cc2)N1C1CCCC1 CHEMBL268157 IC50 560.0 nM
CS(=O)(=O)c1ccc(F)cc1C(=O)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 CHEMBL2180905 IC50 560.0 nM
CC(C)CN1C(=O)CSC1c1ccncc1-c1ccc(Cl)cc1 CHEMBL234490 IC50 580.0 nM
COc1c(Cl)cc(C2C(C(=O)O)=CNC=C2C(=O)OC/C=C/c2ccccc2)cc1Cl CHEMBL2030603 IC50 580.0 nM
CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C CHEMBL334438 IC50 590.0 nM
CC(C)CCN(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N1CCN(Cc2ccccc2)CC1 CHEMBL52679 IC50 590.0 nM
Cc1ccc(-c2cnccc2C2SCC(=O)N2CC(C)C)cc1 CHEMBL234914 IC50 590.0 nM
CC(C)(C)OC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)NCc1ccc([N+](=O)[O-])cc1 CHEMBL172239 IC50 600.0 nM
CC(C)CN1C(=O)CSC1c1cnccc1-c1ccc(Cl)cc1 CHEMBL245171 IC50 600.0 nM
CCOC(=O)C(C)(C)c1ccc2c(c1)c([C@H](C)CO)c(-c1cc(C)cc(C)c1)n2C(=O)OC(C)(C)C CHEMBL1643713 IC50 600.0 nM
CN(C)c1ccc(CNC(=O)[C@H](CSCC2CCCCC2)NC(=O)[C@@H]2CSCN2C(=O)OC(C)(C)C)cc1 CHEMBL366590 IC50 610.0 nM
COc1ccc(COC(=O)[C@H](CSCC2CCCCC2)NC(=O)OC(C)(C)C)cc1 CHEMBL173121 IC50 610.0 nM
COc1ccc(CNC(=O)[C@H](CSCC2CCCCC2)NC(=O)OC(C)(C)C)cc1 CHEMBL65110 IC50 610.0 nM
COc1ccc(CNC(=O)[C@H](CSCC2CCCC2)NC(=O)OC(C)(C)C)cc1 CHEMBL431324 IC50 630.0 nM
O=C1CSC(c2cnccc2-c2ccc(Br)cc2)N1C1CCCC1 CHEMBL232032 IC50 630.0 nM
CC(C)(C)OC(=O)N1CSC[C@H]1C(=O)N[C@@H](CSCC1CCCCC1)C(=O)N1CCC(Nc2ccccc2)CC1 CHEMBL75902 IC50 660.0 nM
CC(C)CCN(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N1CCCCC1 CHEMBL297029 IC50 660.0 nM
CC(C)CN1C(=O)CSC1c1cnccc1-c1ccc(Br)cc1 CHEMBL234938 IC50 660.0 nM
Cc1cc(C)cc(-c2cc3cc(C(C)(C)C(=O)NC(C)(C)C)ccc3n2CC(=O)OC(C)(C)C)c1 CHEMBL1643723 IC50 660.0 nM
CS(=O)(=O)c1ccccc1C(=O)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 CHEMBL2180902 IC50 660.0 nM
CC(C)=CCN(c1ccc(CCc2ccccc2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC(=O)N2CCCCCC2)CC1 CHEMBL312235 IC50 670.0 nM
CC(C)=CCN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)[C@@H](N)CC(C)C)CC1 CHEMBL132818 IC50 670.0 nM
CS(=O)(=O)c1ccc(C#N)cc1C(=O)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 CHEMBL3092199 IC50 670.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)CC1CCCCC1 CHEMBL420920 IC50 680.0 nM
CC1=NC(C)=C(C(=O)O)C(c2cccc(Cl)c2)/C1=C(\O)OC/C(C)=C/c1ccccc1 CHEMBL201566 IC50 680.0 nM
Cc1cc(C)cc(-c2cc3cc(C(=O)NC(C)(C)C)ccc3n2CC(C)O)c1 CHEMBL1643720 IC50 680.0 nM
CC(C)CCN(c1ccc(NCc2ccc(O)cc2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC(=O)N2CCCCCC2)CC1 CHEMBL81973 IC50 690.0 nM
CC(C)CN1C(=O)CSC1c1cccnc1-c1ccc(Br)cc1 CHEMBL231799 IC50 700.0 nM
CCCCOc1cccc(C(F)(F)CNCC(=O)N2CCCCC2)c1 CHEMBL3941638 Ki 700.0 nM
CC1(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CCN(C(=O)c2cc(F)ccc2S(C)(=O)=O)CC1 CHEMBL3092209 IC50 710.0 nM
COc1ccc(COC(=O)[C@H](CSCC2CCCCC2)NC(=O)OCC(C)C)cc1 CHEMBL353717 IC50 720.0 nM
CC(CCC(c1ccccc1)c1ccccc1)(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1 CHEMBL84404 IC50 740.0 nM
CCCC[C@H](NC)C(=O)N[C@H]1CC[C@@H]2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)C[C@@H]21 CHEMBL2414782 pIC50 741.31 nM
CC(C)=CCN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC(C)C)CC1 CHEMBL132914 IC50 750.0 nM
O=C(O)C1=CNC=C(C(=O)OC/C=C/c2ccccc2)C1c1ccc(Cl)c(Cl)c1 CHEMBL2030600 IC50 750.0 nM
CN[C@@H](CC(C)C)C(=O)N[C@H]1CC[C@@H]2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)C[C@@H]21 CHEMBL2414780 IC50 750.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N1CCN(Cc2ccccc2)CC1)N(C)C1CCCCC1 CHEMBL52200 IC50 760.0 nM
NC(=O)c1ccc(C(=O)N2CCC(N(C3CC3)S(=O)(=O)c3cccc(C(F)(F)F)c3)CC2)c(C(F)(F)F)c1 CHEMBL3092207 IC50 760.0 nM
CC(C)CN1C(=O)CS[C@@H]1c1cnccc1-c1ccc(C(F)(F)F)cc1 CHEMBL398158 IC50 770.0 nM
CN[C@@H](CC(C)C)C(=O)N[C@@H]1CC[C@H]2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)C[C@H]21 CHEMBL2414778 IC50 770.0 nM
CC(C)CCN1CCC(C)CC1C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)OC(C)(C)C CHEMBL13959 IC50 780.0 nM
CC1=NC(C)=C(C(=O)O)C(c2cccc(Br)c2)/C1=C(\O)OC/C=C/c1ccccc1 CHEMBL369934 IC50 790.0 nM
CN[C@@H](CC(C)(C)C)C(=O)N[C@H]1CC[C@@H]2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)C[C@@H]21 CHEMBL2414785 IC50 790.0 nM
CC(C)CCN(C)[C@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)C(C)C CHEMBL273705 IC50 830.0 nM
CCN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)[C@H](CC(C)C)NC(=O)N2CCCCCC2)CC1 CHEMBL135637 IC50 830.0 nM
CC1=NC(C)=C(C(=O)O)C(c2cccc(Cl)c2)/C1=C(\O)OC/C=C/C1CCCCC1 CHEMBL201984 IC50 830.0 nM
CN[C@@H](Cc1ccccc1)C(=O)N[C@H]1CC[C@@H]2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)C[C@@H]21 CHEMBL2414786 IC50 860.0 nM
Cc1cc(C)cc(-c2cc3cc(C(C)(C)C(=O)N(C)C)ccc3n2CC(C)O)c1 CHEMBL1643714 IC50 870.0 nM
CC(C)(C)C[C@H](N)C(=O)N[C@H]1CC[C@@H]2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)C[C@@H]21 CHEMBL2414784 IC50 870.0 nM
COc1ccc(COC(=O)[C@H](CSCC2CCCCC2)NC(=O)[C@@H]2CCCN2C(=O)OC(C)(C)C)cc1 CHEMBL366890 IC50 880.0 nM
CC(C)CCN(C)[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NC1CCN(Cc2ccccc2)CC1 CHEMBL52732 IC50 880.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NCCN1CCCCC1)N(C)C1CCCCC1 CHEMBL301152 IC50 880.0 nM
CCc1ccc(-c2ccncc2C2SCC(=O)N2CC(C)C)cc1 CHEMBL243019 IC50 880.0 nM
CCCN[C@@H](C)c1c(-c2cc(C)cc(C)c2)[nH]c2ccc(C(C)(C)C(=O)N3C4CCC3CC4)cc12 CHEMBL1643712 IC50 880.0 nM
CC1=NC(C)=C(C(=O)O)C(c2cccc(Cl)c2)/C1=C(\O)OC/C=C/c1ccc(C)cc1 CHEMBL203041 IC50 890.0 nM
COc1ccc(COC(=O)[C@H](CSCC2CCCCC2)NC(=O)C2CCCC2)cc1 CHEMBL170403 IC50 920.0 nM
COc1ccc(CNC(=O)[C@H](COCC2CCCCC2)NC(=O)OC(C)(C)C)cc1 CHEMBL65360 IC50 950.0 nM
CCC[C@H](NC)C(=O)N[C@H]1CC[C@@H]2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)C[C@@H]21 CHEMBL2414781 pIC50 954.99 nM
CC(C)(c1ccc(O)c(CN2CCCCCC2)c1)c1ccc(O)c(CN2CCCCCC2)c1 CHEMBL421719 IC50 970.0 nM
CS(=O)(=O)c1ccc(F)cc1C(=O)N1CC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)C1 CHEMBL3092211 IC50 970.0 nM
CC(C)CCN1CCN(C)CC1C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)OC(C)(C)C CHEMBL275614 IC50 1000.0 nM
CC(C)CCN1CCCCC1C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)OC(C)(C)C CHEMBL13944 IC50 1000.0 nM
CC(C)=CCN(c1ccccc1)C1CCN(C(=O)[C@H](CC(C)C)NC(=O)N2CCCCCC2)CC1 CHEMBL79868 IC50 1000.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)Cc1cccc(Cl)c1 CHEMBL69748 IC50 1000.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)Cc1ccc(O)cc1 CHEMBL307098 IC50 1000.0 nM
CC(C)C[C@@H](C(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NCCN1CCCCC1)N(C)CC1CCCCC1 CHEMBL408390 IC50 1000.0 nM
CC(C)=CCN(C[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)N1CCCCCC1)c1ccc(OCc2ccccc2)cc1 CHEMBL135646 IC50 1000.0 nM
CC1=NC(C)=C(C(=O)O)C(c2cccc(Cl)c2)/C1=C(\O)OCc1ccc2ccccc2c1 CHEMBL201860 IC50 1000.0 nM
CC1=NC(C)=C(C(=O)O)C(c2cccc(Cl)c2)/C1=C(\O)OC/C=C/c1ccccc1 CHEMBL382072 IC50 1000.0 nM
COC(OC)C1=C(C(=O)OC/C=C/c2ccccc2)C(c2cc(Cl)cc(Cl)c2)C(C(=O)O)=CN1 CHEMBL2030593 IC50 1000.0 nM