O=C(Cc1ccc(C2CC(F)(F)C2)cc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4206509 IC50 1.0 nM
CCc1cc(CC(=O)Nc2ccn(Cc3ccc(C#N)cn3)n2)ccc1OCC(F)(F)F CHEMBL4207291 IC50 1.1 nM
O=C(Cc1ccc(N2CCC(F)(F)C2)nc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4214862 IC50 1.1 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(Cl)cc3)n2)cc1 CHEMBL4204077 IC50 1.1 nM
CC(C)c1ccc(CC(=O)N[C@H](C)c2ccc(OCC(F)(F)F)cn2)cc1 CHEMBL1684950 IC50 1.2 nM
CN1C(=O)C(C)(C)c2cc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)ccc21 CHEMBL4203101 IC50 1.3 nM
O=C(Cc1ccc(OC2CC(F)(F)C2)cc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4211105 IC50 1.4 nM
CC(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4207031 IC50 1.4 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4205005 IC50 1.5 nM
O=C(Cc1ccc2cc[nH]c2c1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4212039 IC50 1.9 nM
Cc1cc(CC(=O)Nc2ccn(Cc3ccc(C#N)cn3)n2)ccc1OCC(F)(F)F CHEMBL4208907 IC50 2.2 nM
CC(C)c1ccc(CC(=O)Nc2ccn(CC3CCC(F)(F)CO3)n2)cc1 CHEMBL4205399 IC50 2.2 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(OC(F)(F)F)cc3)n2)cc1 CHEMBL4204507 IC50 2.2 nM
Cc1cc(CC(=O)Nc2ccn(Cc3ccc(C#N)cn3)n2)ccc1OC(F)(F)F CHEMBL4212176 IC50 2.3 nM
O=C(Cc1ccc2[nH]ccc2c1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4207159 IC50 2.3 nM
CC1(c2ccc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)cc2)COC1 CHEMBL4215974 IC50 2.4 nM
O=C(Cc1ccc(N2CC[C@H](F)C2)nc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4209946 IC50 2.5 nM
Cc1cc(CC(=O)Nc2ccn(Cc3ccc(C#N)cn3)n2)ccc1OCCC(F)(F)F CHEMBL4204573 IC50 2.6 nM
CC(C)(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(C#N)cn3)n2)cc1 CHEMBL4218608 IC50 2.8 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(C#N)c(F)c3)n2)cc1 CHEMBL4218161 IC50 3.1 nM
COc1c(F)cc(Cn2ccc(NC(=O)Cc3ccc(N(C)C)cc3)n2)cc1F CHEMBL4216687 IC50 3.2 nM
CC1(C)OCC(c2ccc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)cc2)O1 CHEMBL4203748 IC50 3.4 nM
Cn1ncc2cc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)ccc21 CHEMBL4203847 IC50 3.4 nM
Cn1c(=O)oc2cc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)ccc21 CHEMBL4207979 IC50 3.4 nM
Cn1ncc2cc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)ccc21 CHEMBL4209481 IC50 3.5 nM
CC1(COc2ccc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)cc2)COC1 CHEMBL4206219 IC50 3.5 nM
C[C@@H]1CN(Cc2ccccc2F)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3924174 IC50 4.0 nM
C[C@@H]1CN(Cc2ccc(C(F)(F)F)o2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3931239 IC50 4.0 nM
O=C(CC(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1 CHEMBL599833 IC50 4.0 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(F)cc3)n2)cc1 CHEMBL4208950 IC50 4.2 nM
O=C(Cc1ccc(C2(F)COC2)cc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4208626 IC50 4.3 nM
CC(C)c1ccc(CC(=O)Nc2nc(Cc3ccc(F)c(F)c3)cs2)cc1 CHEMBL4216756 IC50 4.5 nM
O=C(Cc1ccc(OC2COC2)cc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4204873 IC50 4.6 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3913893 IC50 5.0 nM
C[C@@H]1CN(Cc2cccc(F)c2F)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3906199 IC50 5.0 nM
CC(C)(C)c1ccc(CC(=O)Nc2ncn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4205754 IC50 5.0 nM
CC(C)c1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1 CHEMBL4218617 IC50 5.1 nM
C[C@@H]1CN(Cc2ccccc2)c2cc(F)ccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3936835 IC50 6.0 nM
CC(C(=O)Nc1ccn(Cc2ccc(F)cc2)n1)c1ccc(N(C)C)cc1 CHEMBL4209751 IC50 6.2 nM
N#Cc1ccc(Cn2ccc(NC(=O)Cc3ccc(C4(C(F)(F)F)CC4)cc3)n2)nc1 CHEMBL4217292 IC50 6.4 nM
O=C(NCc1ccc(N2CCC(F)(F)C2)nc1)c1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4218220 IC50 6.5 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(OC(F)F)cc3)n2)cc1 CHEMBL4209376 IC50 6.8 nM
C[C@@H]1CN(Cc2ccc(C(F)(F)F)o2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3969822 IC50 7.0 nM
C[C@@H]1CN(Cc2ccccc2)c2nc(F)ccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3906825 IC50 7.0 nM
Cc1ccc(Cn2ccc(NC(=O)Cc3ccc(N(C)C)cc3)n2)cc1 CHEMBL4213335 IC50 7.0 nM
Cn1ccc2cc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)cnc21 CHEMBL4204295 IC50 7.1 nM
COc1ccc(CNC(=O)N2[C@H](C)CN(Cc3ccccc3)c3ccccc3[C@@H]2C)cc1 CHEMBL3934860 IC50 8.0 nM
C[C@@H]1CN(Cc2cccc(F)c2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3896161 IC50 8.0 nM
Cc1cccc(Cn2ccc(NC(=O)Cc3ccc(N(C)C)cc3)n2)c1 CHEMBL4208413 IC50 8.1 nM
COC(=O)C(CCCN(C)CCCc1nc2ccccc2[nH]1)(c1ccc(Br)cc1)C(C)C CHEMBL468397 IC50 8.17 nM
O=C(Cc1ccc(OCC(F)(F)F)nc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4214341 IC50 10.0 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(C#N)cc3)n2)cc1 CHEMBL4204611 IC50 11.0 nM
COc1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1C CHEMBL4209075 IC50 11.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cc(F)cc(F)c2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3945715 IC50 12.0 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(F)c(F)c3)n2)cn1 CHEMBL4211393 IC50 12.0 nM
C[C@@H]1CN(Cc2ccc(F)c(F)c2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3968363 IC50 13.0 nM
C[C@@H]1CN(Cc2cnc(C(F)(F)F)s2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3918060 IC50 13.0 nM
COc1ccc(CNC(=O)N2[C@H](C)CN(Cc3ccc(C(F)(F)F)o3)c3cnccc3[C@@H]2C)cc1 CHEMBL3938021 IC50 13.0 nM
O=C(Cc1ccc(OC(F)(F)F)cc1)Nc1ccn(Cc2ccccc2)n1 CHEMBL4215146 IC50 13.0 nM
CC(C)c1ccc(CC(=O)Nc2ccn(CCOCC(F)(F)F)n2)cc1 CHEMBL4210292 IC50 14.0 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1 CHEMBL4217227 IC50 14.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ncccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3943761 IC50 15.0 nM
O=C(Cc1ccc(C2CC2)nc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4202684 IC50 15.0 nM
C[C@@H]1CN(Cc2ccccc2)c2nc(Cl)ccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3915799 IC50 16.0 nM
Cn1ncc2cc(CC(=O)Nc3nn(Cc4ccc(F)c(F)c4)cc3C#N)ccc21 CHEMBL4205068 IC50 17.0 nM
CN(C)c1ccc(CNC(=O)c2nc(Cc3ccc(F)c(F)c3)cs2)cc1 CHEMBL4210341 IC50 17.0 nM
Cc1ccc2c(n1)N(Cc1ccccc1)C[C@@H](C)N(C(=O)NCc1ccccc1)[C@H]2C CHEMBL3897825 IC50 18.0 nM
O=C(NCc1ccc(N2CCCC2)nc1)c1coc(Cc2ccc(OC(F)(F)F)cc2)n1 CHEMBL4205975 IC50 18.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cccc(F)c2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3984761 IC50 20.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1Br CHEMBL4206919 IC50 20.0 nM
CC(C)c1ccc(CC(=O)NC(C)c2ccn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4206470 IC50 22.0 nM
CC(C)CCN1C[C@@H](C)N(C(=O)Nc2cccnc2)[C@@H](C)c2ccccc21 CHEMBL3985310 IC50 23.0 nM
C[C@@H]1CN(CC2CCCC2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3915547 IC50 23.0 nM
COc1ccc(Cn2ccc(NC(=O)Cc3ccc(N(C)C)cc3)n2)cc1 CHEMBL4216279 IC50 23.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)C1CCOCC1 CHEMBL3979902 IC50 24.0 nM
CC(C)c1ccc(CNC(=O)c2ccn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4203931 IC50 24.0 nM
CC(C)(C)CCN1CC[C@H](CNC(=O)c2cc(Cl)cc(Cl)c2)[C@H](F)C1 CHEMBL493677 IC50 25.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3897240 IC50 25.0 nM
C[C@@H]1CN(Cc2cccc(C(F)(F)F)n2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3949063 IC50 25.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)N1CCOCC1 CHEMBL3977114 IC50 26.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NC1COC1 CHEMBL3898772 IC50 26.0 nM
[2H]C([2H])(c1ccccc1)N1C[C@@H](C)N(C(=O)Nc2cccnc2)[C@@H](C)c2ccccc21 CHEMBL3921765 IC50 27.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2F)c(-c2ccccc2)c1Br CHEMBL4209876 IC50 28.0 nM
O=C(Nc1ccc(F)cc1)N1N=C(c2ccncc2)CC1c1ccc(F)cc1 CHEMBL3892579 IC50 29.0 nM
CC(C)CCN1C[C@@H](C)N(C(=O)CCc2cccnc2)[C@@H](C)c2ccccc21 CHEMBL3916048 IC50 29.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)CCc1cccnc1 CHEMBL3941448 IC50 31.0 nM
O=C(NCc1ccccc1-n1cccn1)c1nn(-c2ccccc2)c(-c2ccccc2)c1Br CHEMBL4208390 IC50 32.0 nM
C[C@@H]1CN(Cc2cnc(C(F)(F)F)s2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3972616 IC50 33.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)Cc1cncs1 CHEMBL3950196 IC50 34.0 nM
Cn1ncc2cc(CNC(=O)c3cnn(Cc4ccc(F)c(F)c4)n3)ccc21 CHEMBL4217691 IC50 34.0 nM
C[C@@H]1CN(CCOC(C)(C)C)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3939715 IC50 35.0 nM
Cc1ccc(C(c2ccccc2)N2CCN(C(=O)CC(c3ccccc3)c3ccccc3)CC2)c(C)c1 CHEMBL599015 IC50 35.0 nM
CCOc1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1 CHEMBL4203473 IC50 35.0 nM
Cc1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1 CHEMBL4212175 IC50 35.0 nM
CCC(CC)(CNC(=O)C1CCN(Cc2ccccc2F)CC1)c1ccc(F)cc1 CHEMBL1819515 IC50 36.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)CN1CCOCC1 CHEMBL3984489 IC50 36.0 nM
CC(C)(C)NC(=O)CN1CCC(CNC(=O)c2cc(F)cc(Cl)c2)CC1 CHEMBL3934636 IC50 37.0 nM
C[C@@H]1CN(Cc2ccc(C(F)(F)F)o2)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3926060 IC50 37.0 nM
C[C@@H]1CN(Cc2cccc(F)c2F)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3942836 IC50 38.0 nM
O=c1[nH]c2ccccc2n1C1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL1423 Kd 40.0 nM
C[C@@H]1CN(Cc2cnc(C(F)(F)F)s2)c2ccccc2[C@H](C)N1C(=O)CCc1cccnc1 CHEMBL3902886 IC50 40.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cccc(F)c2[C@H](C)N1C(=O)NC1COC1 CHEMBL3926201 IC50 40.0 nM
CN(C)CCCCCN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(-c2ccccc2)cc1 CHEMBL394956 IC50 41.0 nM
CN(C)CCCCCN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(-c2ccccc2)cc1 CHEMBL3144390 IC50 41.0 nM
O=C(Cc1ccc(Cl)cc1)Nc1ccn(Cc2ccccc2)n1 CHEMBL4206874 IC50 41.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3889862 IC50 42.0 nM
O=C(Cc1cccc(Cl)c1)Nc1ccn(Cc2ccccc2)n1 CHEMBL4211644 IC50 44.0 nM
COc1ccc(CN2C[C@@H](C)N(C(=O)NCc3ccccc3)[C@@H](C)c3ccccc32)cn1 CHEMBL3940280 IC50 45.0 nM
CC(C)CCN1C[C@@H](C)N(C(=O)CCc2cccnc2)[C@@H](C)c2c(F)cccc21 CHEMBL3921940 IC50 45.0 nM
O=C(NCc1ncccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1Br CHEMBL4203516 IC50 45.0 nM
CN(C)c1ccc(CNC(=O)c2csc(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4205450 IC50 45.0 nM
Cn1cnc2ccc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)cc21 CHEMBL4211522 IC50 45.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1CCO CHEMBL4213393 IC50 46.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cccc(F)c2[C@H](C)N1C(=O)CCc1cccnc1 CHEMBL3912958 IC50 47.0 nM
C[C@@H]1CN(Cc2ccccc2F)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3972450 IC50 47.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1C(F)F CHEMBL4204992 IC50 49.0 nM
CCNCCc1c(C(=O)NCc2ccccc2OCC(F)(F)F)nn(-c2ccccc2)c1-c1ccccc1 CHEMBL4209001 IC50 52.0 nM
C[C@@H]1CN(Cc2cccnc2F)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3978193 IC50 53.0 nM
O=C(NCc1ccc(C2(F)COC2)cc1)c1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4213283 IC50 53.0 nM
COC(=O)C(CCCN(C)CCCc1nc2cc(C)c(C)cc2[nH]1)(c1ccc(Br)cc1)C(C)C CHEMBL468409 IC50 53.02 nM
CC(C)COc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CC(C(F)(F)F)CC2 CHEMBL4202418 IC50 54.0 nM
Cc1cccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)c1 CHEMBL4207290 IC50 54.0 nM
O=C(CC(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2cccc(Cl)c2)CC1 CHEMBL599404 IC50 55.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1CO CHEMBL4211289 IC50 55.0 nM
CC(C)c1ccc(CC(=O)NCc2ccn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4209235 IC50 55.0 nM
COC(=O)C(CCC(=O)N(C)CCCc1nc2ccccc2[nH]1)(c1ccc(Br)cc1)C(C)C CHEMBL3115194 IC50 56.0 nM
C[C@@H]1CN(Cc2ccccc2)c2nc(C(F)(F)F)ccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3916909 IC50 57.0 nM
O=C(NCc1cccnc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1Br CHEMBL4211809 IC50 58.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1cc(-c2ccccc2)n(-c2ccccc2)n1 CHEMBL4212371 IC50 59.0 nM
CN(C)c1ccc(Cc2nc3cn(Cc4ccc(F)cc4)nc3[nH]2)cc1 CHEMBL4205371 IC50 60.0 nM
O=C(CC(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2cccc(Cl)c2Cl)CC1 CHEMBL599832 IC50 63.0 nM
COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CCc2cc(F)ccc2[C@@H]1C(C)C CHEMBL45816 IC50 64.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ncc(F)cc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3925915 IC50 65.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccc(F)cc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3914936 IC50 68.0 nM
O=C(NCc1ccc2[nH]ccc2c1)c1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4208810 IC50 70.0 nM
C=Cc1c(C(=O)NCc2ccccc2OCC(F)(F)F)nn(-c2ccccc2)c1-c1ccccc1 CHEMBL4216669 IC50 71.0 nM
COc1ccc(CNC(=O)N2[C@H](C)CN(CCC(C)C)c3cnccc3[C@@H]2C)cc1 CHEMBL3910085 IC50 76.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ncc(Cl)cc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3934795 IC50 78.0 nM
COc1ccc(CNC(=O)N2[C@H](C)CN(Cc3ccccc3)c3cnccc3[C@@H]2C)cc1 CHEMBL3956823 IC50 79.0 nM
O=C(CC(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 CHEMBL596946 IC50 81.0 nM
CCC(CC)(CNC(=O)C1CCN(Cc2ccc(F)cc2)CC1)c1ccc(F)cc1 CHEMBL1819517 IC50 82.0 nM
CCc1c(C)c(C(=O)NCc2ccccc2OCC(C)C)n(C)c1Cl CHEMBL4213589 IC50 82.0 nM
CCC(CC)(CNC(=O)C1CCN(Cc2ccccc2)CC1)c1ccc(F)cc1 CHEMBL1819509 IC50 85.0 nM
CCOc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CC(C)(C)CC2 CHEMBL4213830 IC50 87.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccc(F)cc2)c(-c2ccccc2)c1Br CHEMBL4206356 IC50 88.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(CC(F)(F)F)c(-c2ccccc2)c1Br CHEMBL4210724 IC50 88.0 nM
C[C@@H](NC(=O)Cc1ccc(C2CC2)cc1)c1ccc(OCC(F)(F)F)cn1 CHEMBL1684954 IC50 89.0 nM
CCC(CC)(CNC(=O)C1CCN(CCc2ccccc2)CC1)c1ccc(F)cc1 CHEMBL1819511 IC50 89.0 nM
CCC(CC)(CNC(=O)C1CCN(CCc2ccccc2F)CC1)c1ccc(F)cc1 CHEMBL1819521 IC50 90.0 nM
CC1(C)C[C@@H](CN2CCC(F)(CNC(=O)c3cc(Cl)cc(Cl)c3)CC2)CCO1 CHEMBL488817 Activity 93.0 nM
CCC(CC)(CNC(=O)C1CCN(Cc2cccc(OC)c2)CC1)c1ccc(F)cc1 CHEMBL1819519 IC50 94.0 nM
COC(=O)C(CCCN1CCN(c2ccccc2OC)CC1)(c1ccc(Br)cc1)C(C)C CHEMBL513338 IC50 95.0 nM
CC(C)COc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)C[C@H](C)[C@@H](C)C2 CHEMBL4214109 IC50 98.0 nM
CCC1CCCCN1CCCNC(=O)c1ccc2c(=O)n(Cc3ccc(Cl)cc3)c(=S)[nH]c2c1 CHEMBL223908 IC50 100.0 nM
CCOC(=O)C(CCCN(C)CCCc1nc2cc(C)c(C)cc2[nH]1)(c1ccccc1)C(C)C CHEMBL468217 IC50 100.0 nM
O[C@@H](COc1ccc(F)cc1)CN1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 CHEMBL2334601 IC50 100.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2F)c(C2CC2)c1Br CHEMBL4204051 IC50 100.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2CN1C(=O)NCc1ccccc1 CHEMBL3959377 IC50 102.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cncc(F)c2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3898062 IC50 107.0 nM
C[C@@H]1CN(CCOC(C)(C)C)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3977684 IC50 108.0 nM
O=C(CC1c2ccccc2N=C(N2CCCCC2)N1c1ccccc1)NCc1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 CHEMBL251949 IC50 110.0 nM
CCc1c(Br)c(C(=O)NCc2ccccc2OCC(F)(F)F)nn1-c1ccccc1 CHEMBL4215724 IC50 110.0 nM
C[C@@H]1CN(Cc2cnc(C(F)(F)F)s2)c2cccc(F)c2[C@H](C)N1C(=O)CCc1cccnc1 CHEMBL3930876 IC50 115.0 nM
CCC(CC)(CNC(=O)C1CCN(Cc2ccccc2OC)CC1)c1ccc(F)cc1 CHEMBL1819518 IC50 120.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ccccc1Cn1cccn1)CCC(C)(C)C2 CHEMBL4205453 IC50 120.0 nM
NCCCCCNC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(-c2ccccc2)cc1 CHEMBL425534 IC50 130.0 nM
CC(C)(CNC(=O)C1CCN(Cc2ccccc2)CC1)c1ccc(F)cc1 CHEMBL1819508 IC50 130.0 nM
CCC(CC)(CNC(=O)C1CCN(Cc2cccc(F)c2)CC1)c1ccc(F)cc1 CHEMBL1819516 IC50 130.0 nM
CCC(CC)(CNC(=O)C1CCN(CCc2cccc(F)c2)CC1)c1ccc(F)cc1 CHEMBL1819522 IC50 130.0 nM
O=C(NCc1ccccc1F)c1cc(-c2ccccc2)n(-c2ccccc2)n1 CHEMBL4207469 IC50 130.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3895005 IC50 138.0 nM
NCCCCCN1C(Nc2ccc(-c3ccccc3)cc2)=Nc2ccccc2C1CC(=O)NCc1ccccc1 CHEMBL185318 pIC50 139.96 nM
CCC(CC)(CNC(=O)C1CCN(CCc2cccc(OC)c2)CC1)c1ccc(F)cc1 CHEMBL1819525 IC50 140.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cncc(F)c2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3933865 IC50 140.0 nM
CCOCc1ccccc1CNC(=O)c1sc(Br)c2c1CCC(C)(C)C2 CHEMBL4210633 IC50 140.0 nM
O=C(CC(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2ccccc2Cl)CC1 CHEMBL598592 IC50 141.0 nM
CC(C)(C)OC(=O)NCCCCCNC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(-c2ccccc2)cc1 CHEMBL51435 pIC50 159.96 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccc(F)cc2)c(-c2ccccc2)c1C(F)F CHEMBL4218615 IC50 160.0 nM
Cc1ccc(S(=O)(=O)Nc2ccc(CNC(=O)CC3c4ccccc4N=C(N4CCCCC4)N3c3ccccc3)cc2)cc1 CHEMBL112601 pIC50 169.82 nM
CC(C)(C)OC(=O)NCCCCCN1C(Nc2ccc(-c3ccccc3)cc2)=Nc2ccccc2C1CC(=O)NCc1ccccc1 CHEMBL362667 pIC50 169.82 nM
CCC(CC)(CNC(=O)C1CCN(CCc2ccccc2OC)CC1)c1ccc(F)cc1 CHEMBL1819524 IC50 170.0 nM
CC(C)COc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CCC2 CHEMBL4218528 IC50 170.0 nM
COc1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1 CHEMBL4210726 IC50 170.0 nM
C[C@@H]1CN(Cc2ccccc2)c2c(F)cccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3908881 IC50 178.0 nM
CCC(CC)(CNC(=O)C1CCN(CCc2ccc(F)cc2)CC1)c1ccc(F)cc1 CHEMBL1819523 IC50 180.0 nM
CCOCc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CC(C)(C)CC2 CHEMBL4215213 IC50 180.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1cccnc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4213286 IC50 180.0 nM
CC(C)c1ccc(Cc2nnc(-c3ccn(Cc4ccc(F)c(F)c4)n3)[nH]2)cc1 CHEMBL4213632 IC50 180.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cc(OCC(F)(F)F)ccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3974827 IC50 187.0 nM
COc1cccc2c1[C@H](C)N(C(=O)Nc1cccnc1)[C@H](C)CN2Cc1ccccc1 CHEMBL3917820 IC50 188.0 nM
COC(=O)C(CCCN(C)CCCc1nc2ccccc2[nH]1)(c1ccc(OC)cc1)C(C)C CHEMBL468227 IC50 190.0 nM
O=C(CCCNCC1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 CHEMBL1215314 IC50 190.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2F)c(-c2ccccc2)c1C(F)F CHEMBL4214199 IC50 190.0 nM
C[C@H]1c2ccccc2N(Cc2ccccc2)CCN1C(=O)NCc1ccccc1 CHEMBL3890307 IC50 193.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cnccc2[C@H](C)N1C(=O)CCc1ccc(F)cc1 CHEMBL3951580 IC50 196.0 nM
CCC(CC)(CNC(=O)C1CCN(Cc2ccc(OC)cc2)CC1)c1ccc(F)cc1 CHEMBL1819520 IC50 200.0 nM
O=C(NCc1ccccc1)c1cc(-c2ccccc2)n(-c2ccccc2)n1 CHEMBL4216796 IC50 200.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1CCNC1CC1 CHEMBL4205063 IC50 200.0 nM
CC(C)OCc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CC(C)(C)CC2 CHEMBL4202587 IC50 200.0 nM
O=c1n(CCCCc2ccccc2)c2ccccc2n1C1CCN(CCCCc2ccccc2)CC1 CHEMBL5396601 IC50 209.0 nM
CCOc1ccccc1CNC(=O)c1sc(Br)c2c1CCC(C)(C)C2 CHEMBL4215557 IC50 210.0 nM
C[C@@H]1CN(C(=O)NCc2ccccc2)[C@@H](C)c2ccccc2N1Cc1ccccc1 CHEMBL3904762 IC50 211.0 nM
O=c1n(CCCCc2ccccc2)c2ccccc2n1C1CCN(CCCCc2cccc(F)c2)CC1 CHEMBL5430690 IC50 211.0 nM
O=c1n(CCCCc2cccc(F)c2)c2ccccc2n1C1CCN(CCCCc2cccc(F)c2)CC1 CHEMBL5399702 IC50 217.0 nM
O=C(NCC1(c2ccc(F)cc2)CCCC1)C1CCN(Cc2ccccc2)CC1 CHEMBL1819501 IC50 220.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cnc(Cl)cc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3986638 IC50 220.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2cccc(F)c2)c(-c2ccccc2)c1Br CHEMBL4211241 IC50 220.0 nM
Cc1ccc2c(c1)N(Cc1ccccc1)C[C@@H](C)N(C(=O)Nc1cccnc1)[C@H]2C CHEMBL3903942 IC50 227.0 nM
COC(=O)CC1c2ccccc2N=C(N(C)CCCCCN(C)C)N1c1ccc(-c2ccccc2)cc1 CHEMBL400229 IC50 230.0 nM
O[C@H](COc1ccc(F)cc1)CN1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 CHEMBL2334265 IC50 230.0 nM
CCOCc1ccc(CNC(=O)c2sc(C)c3c2C[C@H]2[C@@H]3C2(C)C)cc1 CHEMBL4209762 IC50 230.0 nM
CCC(CC)(CNC(=O)C1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1 CHEMBL1819512 IC50 240.0 nM
CCN(CC)CCc1c(C(=O)NCc2ccccc2OCC(F)(F)F)nn(-c2ccccc2)c1-c1ccccc1 CHEMBL4204657 IC50 240.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ccccc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4212744 IC50 240.0 nM
CCc1c(C)c(Cl)n(C)c1C(=O)NCc1ccccc1OCC(C)C CHEMBL4210232 IC50 240.0 nM
O=C(CCCc1ccccc1)N1CCC(n2c(=O)n(CCCCc3ccccc3)c3ccccc32)CC1 CHEMBL5399421 IC50 240.0 nM
CCOC(=O)C(CCCN(C)CCCc1nc2ccccc2[nH]1)(c1ccccc1)C(C)C CHEMBL467174 IC50 250.0 nM
COC(=O)C(CCCN(C)CCCc1nc2cc(OC)ccc2[nH]1)(c1ccc(Br)cc1)C(C)C CHEMBL468408 IC50 250.0 nM
CCC(CC)(CNC(=O)C1CCN(CCCCc2ccccc2)CC1)c1ccc(F)cc1 CHEMBL1819513 IC50 250.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(Cc2ccccc2)c(-c2ccccc2)c1C(F)F CHEMBL4209062 IC50 250.0 nM
Cn1nc(C(=O)NCc2ccccc2OCC(F)(F)F)c(C(F)F)c1-c1ccccc1 CHEMBL4211471 IC50 250.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ncccc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4211734 IC50 250.0 nM
Cc1ccccc1Cn1ccc(NC(=O)Cc2ccc(N(C)C)cc2)n1 CHEMBL4217744 IC50 250.0 nM
CN(C)CCCCCSC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(-c2ccc(F)cc2)cc1 CHEMBL4632832 IC50 250.0 nM
C[C@@H]1CN(c2ccccc2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3969267 IC50 256.0 nM
CN(CCCCCN1CCCC1)C1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(-c2ccccc2)cc1 CHEMBL248088 IC50 260.0 nM
CCOC(=O)C(CCCN1CCN(Cc2ccc(F)cc2)CC1)(c1ccccc1)C(C)C CHEMBL513836 IC50 260.0 nM
CCC(CC)(CNC(=O)C1CCN(CCOc2ccccc2)CC1)c1ccc(F)cc1 CHEMBL1819514 IC50 260.0 nM
[2H]C([2H])(c1ccccc1)N1C[C@@H](C)N(C(=O)NCc2ccccc2)[C@@H](C)c2ccncc21 CHEMBL3980491 IC50 260.0 nM
COCc1ccccc1CNC(=O)c1sc(Br)c2c1CCC(C)(C)C2 CHEMBL4204934 IC50 260.0 nM
C[C@@H]1c2ccccc2N(Cc2ccccc2)C[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3951718 IC50 262.0 nM
C[C@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3978731 IC50 279.0 nM
O=C(CCCN1CCN(Cc2ccc(Cl)cc2)CC1)Nc1ccc(Cl)cc1Cl CHEMBL225988 IC50 280.0 nM
COC(=O)C(CCCN1CCN(Cc2cccc(C(F)(F)F)c2)CC1)(c1ccc(Br)cc1)C(C)C CHEMBL512604 IC50 280.0 nM
CC(C)c1ccc(CNCCCC(=O)N2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)cc1 CHEMBL1215391 IC50 280.0 nM
Cn1nc(C(=O)NCc2ccccc2OCC(F)(F)F)c(Br)c1-c1ccccc1 CHEMBL4215680 IC50 280.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cc(Br)ccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3974104 IC50 286.0 nM
C[C@H]1c2ccccc2N(Cc2ccccc2)[C@@H](C)CN1C(=O)NCc1ccccc1 CHEMBL3950664 IC50 293.0 nM
COC(=O)CC1c2ccccc2N=C(Nc2ccc(-c3ccccc3)cc2)N1CCCCCN CHEMBL182332 pIC50 299.92 nM
C[C@@H]1C(=O)N(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3899264 IC50 304.0 nM
O=C(NCc1ccccc1)N1CCN(Cc2ccccc2)c2ccccc2C1 CHEMBL3979642 IC50 305.0 nM
COc1ccc(CNC(=O)CC2c3ccccc3N=C(N3CCN(CCN(C)C)CC3)N2c2ccc(-c3ccccc3)cc2)cc1 CHEMBL3093781 IC50 310.0 nM
CN(C)CCCCN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(-c2ccccc2)cc1 CHEMBL3093776 IC50 310.0 nM
CC(C)COc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CCC(C)(C)C2 CHEMBL4215580 IC50 310.0 nM
COC(=O)C(CCCN1CCN(Cc2ccc(OC)c(OC)c2OC)CC1)(c1ccc(Br)cc1)C(C)C CHEMBL468157 IC50 320.0 nM
COc1ccc(CN2CCC(C(=O)NCC3(c4ccc(F)cc4)CCCCC3)CC2)cc1OC CHEMBL1819500 IC50 320.0 nM
CN(C)CCN1CCN(C2=Nc3ccccc3C(CC(=O)NCc3ccc(F)cc3)N2c2ccc(-c3ccccc3)cc2)CC1 CHEMBL3093780 IC50 320.0 nM
Cc1sc(C(=O)NCc2ccccc2C(F)(F)F)c2c1[C@@H]1[C@H](C2)C1(C)C CHEMBL4202762 IC50 320.0 nM
Cn1c(C#N)c2c(c1C(=O)NCc1cccnc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4206268 IC50 320.0 nM
Cc1sc(C(=O)NCc2cccc(OC(F)(F)F)c2)c2c1[C@@H]1[C@H](C2)C1(C)C CHEMBL4214944 IC50 330.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(Cc2ccccc2)c(-c2ccccc2)c1Br CHEMBL4205006 IC50 335.0 nM
COC(=O)CC1c2ccccc2N=C(N(C)CCCCCN2CCCC2)N1c1ccc(-c2ccccc2)cc1 CHEMBL239375 pIC50 339.63 nM
CCOC(=O)C(CCCN1CCN(Cc2ccc(OC)cc2)CC1)(c1ccccc1)C(C)C CHEMBL467384 IC50 340.0 nM
CN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccc([N+](=O)[O-])cc2)N1c1ccccc1 CHEMBL457084 pIC50 349.95 nM
CC(C)COc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CN(C(=O)OC(C)(C)C)C2 CHEMBL4206782 IC50 350.0 nM
CC(C)CNCCCC(=O)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 CHEMBL1215248 IC50 360.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cnccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3917185 IC50 360.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2cccc(F)c2)c(-c2ccccc2)c1C(F)F CHEMBL4206873 IC50 360.0 nM
COC(=O)CC1c2ccccc2N=C(Nc2ccc(-c3ccccc3)cc2)N1CCCCCNC(=O)OC(C)(C)C CHEMBL182518 pIC50 369.83 nM
O=C(CCCN1CCN(Cc2ccc(Cl)cc2)CC1)Nc1ccc(Cl)cc1 CHEMBL225857 IC50 370.0 nM
CCCC(CCC)(CNC(=O)C1CCN(Cc2ccccc2)CC1)c1ccc(F)cc1 CHEMBL1819510 IC50 370.0 nM
COc1cc2c(cc1F)N(Cc1ccccc1)C[C@@H](C)N(C(=O)Nc1cccnc1)[C@H]2C CHEMBL3899835 IC50 370.0 nM
O=C(CC(c1ccccc1)c1ccccc1)N1CCN(C2c3ccccc3-c3ccccc32)CC1 CHEMBL3925602 IC50 371.0 nM
CN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccc(N)cc2)N1c1ccccc1 CHEMBL459245 IC50 380.0 nM
Cn1c(C(=O)NCc2cccnc2OCC(F)(F)F)c2c(c1C(F)(F)F)CC(C)(C)CC2 CHEMBL4211150 IC50 380.0 nM
COC(=O)C(CCCN1CCN(Cc2cccc(C)c2)CC1)(c1ccc(Br)cc1)C(C)C CHEMBL468849 IC50 390.0 nM
O=C(NCC1(c2ccc(F)cc2)CCC1)C1CCN(Cc2ccccc2)CC1 CHEMBL1819502 IC50 390.0 nM
COc1ccc(CNC(=O)CC2c3ccccc3N=C(N(C)CCCCCN(C)C)N2c2ccc(-c3ccccc3)cc2)cc1 CHEMBL3093774 IC50 390.0 nM
COc1ccc2c(c1)[C@H](C)N(C(=O)Nc1cccnc1)[C@H](C)CN2Cc1ccccc1 CHEMBL3925393 IC50 390.0 nM
CN(C)CCCCCSC1=Nc2ccccc2C(CC(=O)NCc2ccc(F)cc2)N1c1ccc(-c2ccc(F)cc2)cc1 CHEMBL4648577 IC50 400.0 nM
O=C(CN1CCN(C(c2ccccc2)c2ccccc2)CC1)C1c2ccccc2-c2ccccc21 CHEMBL3922836 IC50 404.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(CC(F)(F)F)c(-c2ccccc2)c1C(F)F CHEMBL4207289 IC50 410.0 nM
CCNCCCC(=O)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 CHEMBL1215247 IC50 420.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)OCc1ccccc1 CHEMBL3936568 IC50 420.0 nM
CN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2)N1c1ccccc1 CHEMBL593659 pIC50 429.54 nM
[2H]C([2H])(c1ccccc1)N1C[C@@H](C)N(C(=O)Nc2cccnc2)[C@@H](C)c2ccncc21 CHEMBL3919009 IC50 441.0 nM
O=C(NCc1ccccc1)[C@@H]1COC(=O)[C@H](Cc2ccc(Cl)cc2)N1 CHEMBL386255 IC50 450.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)N(C)Cc1ccccc1 CHEMBL3951240 IC50 457.0 nM
Cc1ccc(CNC(=O)CC2c3ccccc3N=C(N3CCN(CCN(C)C)CC3)N2c2ccc(-c3ccccc3)cc2)cc1 CHEMBL3093779 IC50 460.0 nM
COCc1ccc(CNC(=O)c2sc(Br)c3c2CCC(C)(C)C3)cc1 CHEMBL4217576 IC50 460.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ccccc1OCCC(F)(F)F)CCC(C)(C)C2 CHEMBL4216897 IC50 460.0 nM
C[C@@H]1CN(Cc2cccnc2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3950824 IC50 476.0 nM
COC(=O)C(CCCN1CCN(Cc2ccc(OC)cc2)CC1)(c1ccc(Br)cc1)C(C)C CHEMBL468156 IC50 480.0 nM
COc1cccc(N2CCN(C[C@H](O)COc3ccc(C(F)(F)F)cc3)CC2)c1 CHEMBL2334271 IC50 480.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ccccc1Cn1cncn1)CCC(C)(C)C2 CHEMBL4217174 IC50 480.0 nM
Cc1ccccc1CC(=O)Nc1ccn(Cc2ccccc2)n1 CHEMBL4215681 IC50 490.0 nM
O=C(NCC1(c2ccc(F)cc2)CCCCC1)C1CCN(Cc2ccccc2)CC1 CHEMBL1819499 IC50 510.0 nM
Cc1onc(CNC(=O)c2c3c(c(Cl)n2C)CC(C)(C)CC3)c1Cn1cccn1 CHEMBL4216691 IC50 510.0 nM
CN(C)CCN1CCN(C2=Nc3ccccc3C(CC(=O)NCc3ccc(N(S(C)(=O)=O)S(C)(=O)=O)cc3)N2c2ccc(-c3ccccc3)cc2)CC1 CHEMBL3233080 IC50 520.0 nM
Fc1ccc(C(c2ccc(F)cc2)N2CCN(C/C=C/c3ccccc3)CC2)cc1 CHEMBL30008 Kd 530.0 nM
CC(C)Oc1ccccc1CNC(=O)c1sc(Br)c2c1CCC(C)(C)C2 CHEMBL4206884 IC50 530.0 nM
Cc1sc(C(=O)NCc2cccc(C(F)(F)F)c2)c2c1[C@@H]1[C@H](C2)C1(C)C CHEMBL4203292 IC50 540.0 nM
CN(C)CCCCCCN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(-c2ccccc2)cc1 CHEMBL3093777 IC50 550.0 nM
COC(=O)CC1c2ccccc2N=C(NCCCCCN)N1c1ccc(-c2ccccc2)cc1 CHEMBL360359 pIC50 559.76 nM
CC(C)(C)OC(=O)NCCCCCNC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccccc1 CHEMBL481134 IC50 570.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1S(=O)(=O)c1cn(C)cn1 CHEMBL3923527 IC50 576.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cc(C#N)ccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3944657 IC50 582.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cccnc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3963167 IC50 597.0 nM
O=C(CCCNCc1ccc([N+](=O)[O-])cc1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 CHEMBL1215316 IC50 600.0 nM
CN(C)C(=O)NCCCN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccc(F)cc2)N1c1ccc(-c2ccccc2)cc1 CHEMBL3233076 IC50 600.0 nM
Cc1sc(C(=O)NCc2ccccc2Cl)c2c1[C@@H]1[C@H](C2)C1(C)C CHEMBL4207112 IC50 600.0 nM
C[C@@H]1CN(Cc2ccccn2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3976890 IC50 605.0 nM
CC(C)CCN1C[C@@H](C)N(C(=O)Nc2cccnc2)[C@@H](C)c2ccncc21 CHEMBL3927924 IC50 613.0 nM
COc1ccc2c(c1)N(Cc1ccccc1)C[C@@H](C)N(C(=O)Nc1cccnc1)[C@H]2C CHEMBL3947185 IC50 627.0 nM
Cc1ccc(S(=O)(=O)Nc2ccc(CNC(=O)CC3c4ccccc4N=C(N(C)C)N3c3ccccc3)cc2)cc1 CHEMBL460646 pIC50 629.51 nM
CCCc1nc(-c2ccccc2)c(CNCCCN2CCN(c3cccc(C(F)(F)F)c3)CC2)o1 CHEMBL1170780 IC50 650.0 nM
COC(=O)C(CCC(=O)N1CCN(c2ccccc2OC)CC1)(c1ccc(Br)cc1)C(C)C CHEMBL3115195 IC50 654.0 nM
O=C(CC1c2ccccc2N=C(SCCCCCN2CCCC2)N1c1ccc(-c2ccccc2)cc1)NCc1ccccc1 CHEMBL4643629 IC50 660.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2C(=O)N1CCc1ccccc1 CHEMBL3970445 IC50 676.0 nM
COC(=O)CC1c2ccccc2N=C(NCCCCCNC(=O)OC(C)(C)C)N1c1ccc(-c2ccccc2)cc1 CHEMBL182968 pIC50 679.2 nM
COc1ccc(CNC(=O)CC2c3ccccc3N=C(N(C)CCCCCCN(C)C)N2c2ccc3ccccc3c2)cc1 CHEMBL3233075 IC50 730.0 nM
COC(=O)C(CCCN1CCN(Cc2ccccc2F)CC1)(c1ccc(Br)cc1)C(C)C CHEMBL511386 IC50 740.0 nM
COc1ccc(C(c2ccc(OC)cc2)N2CCN(C(=O)CC(c3ccccc3)c3ccccc3)CC2)cc1 CHEMBL598603 IC50 745.0 nM
O=C(CCCN1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)Nc1ccc(Cl)cc1Cl CHEMBL225989 IC50 750.0 nM
CN(CC1(c2ccc(F)cc2)CCCCC1)C(=O)C1CCN(Cc2ccccc2)CC1 CHEMBL1819506 IC50 750.0 nM
CCN1C[C@@H](C)N(C(=O)NCc2ccccc2)[C@@H](C)c2ccccc21 CHEMBL3950065 IC50 754.0 nM
O[C@H](COc1ccc(C(F)(F)F)cc1)CN1CCN(Cc2c(F)cccc2Cl)CC1 CHEMBL2334275 IC50 760.0 nM
Cn1cc2c(c1C(=O)NCc1cccnc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4203828 IC50 760.0 nM
CCC(CC)(CNC(=O)C1CCN(CCc2ccc(OC)cc2)CC1)c1ccc(F)cc1 CHEMBL1819526 IC50 770.0 nM
COC(=O)c1coc(CN2CCN(C(=O)CC(c3ccc(F)cc3)c3ccc(Br)cc3)CC2)n1 CHEMBL1645164 IC50 860.0 nM
O=C(CC1(c2ccc(F)cc2)CCCCC1)NC1CCN(Cc2ccccc2)CC1 CHEMBL1819507 IC50 860.0 nM
CCN1C(N2CCCCC2)=Nc2ccccc2C1CC(=O)NCc1ccc([N+](=O)[O-])cc1 CHEMBL590128 pIC50 868.96 nM
Cc1ccccc1CNC(=O)c1sc(C)c2c1C[C@H]1[C@@H]2C1(C)C CHEMBL4207625 IC50 870.0 nM
C[C@@H]1CN(CC2CCCCO2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3948466 IC50 875.0 nM
COC(=O)C(CCCN(C)CCCc1nc2cc(OC)ccc2[nH]1)(c1ccc(OC)cc1)C(C)C CHEMBL468228 IC50 880.0 nM
CN(C)C(=O)NCCCN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccc(F)cc2)N1c1ccc(C2CCCCC2)cc1 CHEMBL4779125 IC50 890.0 nM
O=C(CC1c2ccccc2N=C(N2CCCCC2)N1c1ccccc1)NCc1ccccc1 CHEMBL114695 IC50 900.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ccncc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4204013 IC50 910.0 nM
COc1ccc(C2(C(=O)Nc3ccn(Cc4ccccc4)n3)CC2)cc1 CHEMBL4217085 IC50 920.0 nM
CC1CCCCN1CCCNC(=O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)C2=O CHEMBL558593 IC50 930.0 nM
CCN1C(N2CCCCC2)=Nc2ccccc2C1CC(=O)NCc1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL217660 pIC50 959.4 nM
O=C(NCCN1CCCCC1)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)C2=O CHEMBL537442 IC50 960.0 nM
COC(=O)C(CCCN1CCN(Cc2cccc(F)c2)CC1)(c1ccc(Br)cc1)C(C)C CHEMBL466767 IC50 980.0 nM
CC(C)[C@@H]1N[C@H](C(=O)NCc2ccccc2)COC1=O CHEMBL424892 IC50 990.0 nM
Cc1ccc(CNC(=O)c2sc(C)c3c2C[C@H]2[C@@H]3C2(C)C)cc1 CHEMBL4213521 IC50 1000.0 nM
C=C(C)[C@H](CC=C(C)C)Cc1c(O)cc(O)c2c1O[C@H](c1ccc(O)cc1O)CC2=O CHEMBL243148 IC50 1000.0 nM
CC(C)=CCc1c(O)cc(O)c2c1O[C@H](c1ccc(O)cc1)CC2=O CHEMBL376915 IC50 1000.0 nM
CC(C)=CCc1c(O)cc2c(c1O)C(=O)CC(c1ccc(O)cc1)O2 CHEMBL1537093 IC50 1000.0 nM