CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4205005 IC50 3.4 nM
CN1C(=O)C(C)(C)c2cc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)ccc21 CHEMBL4203101 IC50 3.8 nM
O=C(Nc1cc(F)cc(F)c1)N1CCC2(CC1)C(=O)N(c1ccc(F)c(Cl)c1)C2c1ccccn1 CHEMBL1210565 IC50 4.0 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(Cl)cc3)n2)cc1 CHEMBL4204077 IC50 4.1 nM
CC1(c2ccc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)cc2)COC1 CHEMBL4215974 IC50 4.3 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(OC(F)(F)F)cc3)n2)cc1 CHEMBL4204507 IC50 5.1 nM
O=C(Cc1ccc2cc[nH]c2c1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4212039 IC50 5.3 nM
CC(C)c1ccc(CC(=O)Nc2ccn(CC3CCC(F)(F)CO3)n2)cc1 CHEMBL4205399 IC50 5.5 nM
C[C@@H]1CN(Cc2ccccc2)c2nc(F)ccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3906825 IC50 6.0 nM
CC(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4207031 IC50 6.0 nM
O=C(Cc1ccc(C2CC(F)(F)C2)cc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4206509 IC50 6.1 nM
CC(C)OCc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CC(C)(C)CC2 CHEMBL4202587 IC50 6.6 nM
O=C(Cc1ccc(N2CCC(F)(F)C2)nc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4214862 IC50 6.7 nM
Cc1cc(CC(=O)Nc2ccn(Cc3ccc(C#N)cn3)n2)ccc1OCC(F)(F)F CHEMBL4208907 IC50 7.0 nM
CC(C)(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(C#N)cn3)n2)cc1 CHEMBL4218608 IC50 7.5 nM
CCc1cc(CC(=O)Nc2ccn(Cc3ccc(C#N)cn3)n2)ccc1OCC(F)(F)F CHEMBL4207291 IC50 7.8 nM
COc1c(F)cc(Cn2ccc(NC(=O)Cc3ccc(N(C)C)cc3)n2)cc1F CHEMBL4216687 IC50 7.8 nM
CC(C)c1ccc(CC(=O)N[C@H](C)c2ccc(OCC(F)(F)F)cn2)cc1 CHEMBL1684950 IC50 8.2 nM
Cn1ncc2cc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)ccc21 CHEMBL4203847 IC50 8.4 nM
Cn1ncc2cc(CC(=O)Nc3cnn(Cc4ccc(F)c(F)c4)n3)ccc21 CHEMBL4209481 IC50 8.6 nM
C[C@@H]1CN(Cc2cccc(F)c2F)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3906199 IC50 9.0 nM
CC1(C)OCC(c2ccc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)cc2)O1 CHEMBL4203748 IC50 10.0 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(OC(F)F)cc3)n2)cc1 CHEMBL4209376 IC50 10.0 nM
Cc1ccc(Cn2ccc(NC(=O)Cc3ccc(N(C)C)cc3)n2)cc1 CHEMBL4213335 IC50 10.0 nM
C[C@@H]1CN(Cc2ccccc2F)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3924174 IC50 11.0 nM
O=C(Cc1ccc(OC2CC(F)(F)C2)cc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4211105 IC50 11.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cc(F)ccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3936835 IC50 12.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ccccc1Cn1cccn1)CCC(C)(C)C2 CHEMBL4205453 IC50 12.0 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(F)cc3)n2)cc1 CHEMBL4208950 IC50 12.0 nM
C[C@@H]1CN(Cc2ccc(C(F)(F)F)o2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3969822 IC50 13.0 nM
O=C(Cc1ccc(C2(F)COC2)cc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4208626 IC50 13.0 nM
COc1ccc(CNC(=O)N2[C@H](C)CN(Cc3ccccc3)c3ccccc3[C@@H]2C)cc1 CHEMBL3934860 IC50 14.0 nM
C[C@@H]1CN(Cc2cccc(F)c2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3896161 IC50 14.0 nM
C[C@@H]1CN(Cc2ccc(C(F)(F)F)o2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3931239 IC50 14.0 nM
O=C(Cc1ccc2[nH]ccc2c1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4207159 IC50 14.0 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(C#N)c(F)c3)n2)cc1 CHEMBL4218161 IC50 14.0 nM
C[C@@H]1CN(Cc2cnc(C(F)(F)F)s2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3918060 IC50 15.0 nM
Cn1c(=O)oc2cc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)ccc21 CHEMBL4207979 IC50 15.0 nM
O=C(Nc1ccc(F)cc1)N1N=C(c2ccc(Br)cc2)CC1c1ccc(F)cc1 CHEMBL3894794 IC50 16.0 nM
O=C(Nc1cccc(C(F)(F)F)c1)N1CCC2(CC1)C(=O)N(c1ccc(F)c(F)c1)C2c1ccccn1 CHEMBL1210629 IC50 17.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3913893 IC50 17.0 nM
O=C(Nc1cc(F)cc(F)c1)N1CCC2(CC1)C(=O)N(c1cccc(Cl)c1)C2c1ccccn1 CHEMBL1210766 IC50 18.0 nM
C[C@@H]1CN(Cc2ccc(F)c(F)c2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3968363 IC50 18.0 nM
N#Cc1ccc(Cn2ccc(NC(=O)Cc3ccc(C4(C(F)(F)F)CC4)cc3)n2)nc1 CHEMBL4217292 IC50 18.0 nM
Cc1cc(CC(=O)Nc2ccn(Cc3ccc(C#N)cn3)n2)ccc1OCCC(F)(F)F CHEMBL4204573 IC50 18.0 nM
CC(C)COc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)C[C@H](C)[C@@H](C)C2 CHEMBL4214109 IC50 20.0 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(C#N)cc3)n2)cc1 CHEMBL4204611 IC50 20.0 nM
O=C(Nc1ccc(F)cc1)N1N=C(c2ccncc2)C[C@H]1c1ccc(F)cc1 CHEMBL3962647 IC50 21.0 nM
CCOc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CC(C)(C)CC2 CHEMBL4213830 IC50 21.0 nM
CCOCc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CC(C)(C)CC2 CHEMBL4215213 IC50 21.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ccccc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4212744 IC50 21.0 nM
CC(C)COc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CC(C(F)(F)F)CC2 CHEMBL4202418 IC50 21.0 nM
CCc1c(C)c(C(=O)NCc2ccccc2OCC(C)C)n(C)c1Cl CHEMBL4213589 IC50 21.0 nM
Cn1ncc2cc(CC(=O)Nc3nn(Cc4ccc(F)c(F)c4)cc3C#N)ccc21 CHEMBL4205068 IC50 21.0 nM
O=C(Cc1ccc(N2CC[C@H](F)C2)nc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4209946 IC50 21.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cc(F)cc(F)c2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3945715 IC50 22.0 nM
CC(C)c1ccc(CC(=O)Nc2nc(Cc3ccc(F)c(F)c3)cs2)cc1 CHEMBL4216756 IC50 22.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ncccc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4211734 IC50 23.0 nM
CC(C)c1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1 CHEMBL4218617 IC50 23.0 nM
COc1ccc(CNC(=O)N2[C@H](C)CN(Cc3ccc(C(F)(F)F)o3)c3cnccc3[C@@H]2C)cc1 CHEMBL3938021 IC50 24.0 nM
O=C(Nc1ccc(F)cc1)N1N=C(c2ccccc2)CC1c1ccc(F)cc1 CHEMBL3981633 IC50 25.0 nM
[2H]C([2H])(c1ccccc1)N1C[C@@H](C)N(C(=O)Nc2cccnc2)[C@@H](C)c2ccccc21 CHEMBL3921765 IC50 25.0 nM
COCc1ccccc1CNC(=O)c1sc(Br)c2c1CCC(C)(C)C2 CHEMBL4204934 IC50 25.0 nM
Cc1onc(CNC(=O)c2c3c(c(Cl)n2C)CC(C)(C)CC3)c1Cn1cccn1 CHEMBL4216691 IC50 25.0 nM
Cc1cc(CC(=O)Nc2ccn(Cc3ccc(C#N)cn3)n2)ccc1OC(F)(F)F CHEMBL4212176 IC50 25.0 nM
CC(C)COc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CCC2 CHEMBL4218528 IC50 27.0 nM
CCc1c(C)c(Cl)n(C)c1C(=O)NCc1ccccc1OCC(C)C CHEMBL4210232 IC50 27.0 nM
Cc1ccc2c(n1)N(Cc1ccccc1)C[C@@H](C)N(C(=O)NCc1ccccc1)[C@H]2C CHEMBL3897825 IC50 28.0 nM
O=C1N(c2ccc(F)c(Cl)c2)C(c2ccccn2)C12CCN(c1nc3cc(F)c(C(F)(F)F)cc3[nH]1)CC2 CHEMBL1210902 IC50 29.0 nM
C[C@@H]1CN(Cc2cnc(C(F)(F)F)s2)c2ccccc2[C@H](C)N1C(=O)CCc1cccnc1 CHEMBL3902886 IC50 30.0 nM
O=C(NCc1ccc(N2CCC(F)(F)C2)nc1)c1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4218220 IC50 30.0 nM
O=C(NCc1ccc(N2CCCC2)nc1)c1coc(Cc2ccc(OC(F)(F)F)cc2)n1 CHEMBL4205975 IC50 30.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3897240 IC50 31.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ncccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3943761 IC50 31.0 nM
CC(C)(C)c1ccc(CC(=O)Nc2ncn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4205754 IC50 31.0 nM
COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CCc2cc(F)ccc2[C@@H]1C(C)C CHEMBL45816 IC50 32.0 nM
O=C(Cc1ccc(OC2COC2)cc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4204873 IC50 32.0 nM
O=C(Nc1ccc(F)cc1)N1N=C(c2ccncc2)CC1c1ccc(F)cc1 CHEMBL3892579 IC50 33.0 nM
COc1ccc([C@]2(CCO)CC(c3cccnc3)=NN2C(=O)Nc2ccc(Br)cc2)cc1 CHEMBL3928071 IC50 33.0 nM
COc1ccc(CN2C[C@@H](C)N(C(=O)NCc3ccccc3)[C@@H](C)c3ccccc32)cn1 CHEMBL3940280 IC50 33.0 nM
Cn1c(C#N)c2c(c1C(=O)NCc1ncccc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4210625 IC50 33.0 nM
CC1(COc2ccc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)cc2)COC1 CHEMBL4206219 IC50 34.0 nM
CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1)C(=O)OC#N CHEMBL1210983 IC50 35.0 nM
Cn1ccc2cc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)cnc21 CHEMBL4204295 IC50 35.0 nM
C[C@@H]1CN(Cc2ccccc2)c2nc(Cl)ccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3915799 IC50 36.0 nM
Cc1cccc(Cn2ccc(NC(=O)Cc3ccc(N(C)C)cc3)n2)c1 CHEMBL4208413 IC50 36.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)CCc1cccnc1 CHEMBL3941448 IC50 38.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ccccc1Cn1cncn1)CCC(C)(C)C2 CHEMBL4217174 IC50 38.0 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1 CHEMBL4217227 IC50 38.0 nM
CCOCc1ccccc1CNC(=O)c1sc(Br)c2c1CCC(C)(C)C2 CHEMBL4210633 IC50 39.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1cccnc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4213286 IC50 39.0 nM
CS(=O)(=O)c1ccc(C2CC(c3ccccc3)=NN2C(=O)Nc2ccc(F)cc2)cc1 CHEMBL3964030 IC50 40.0 nM
O=C(Nc1ccc(F)c(F)c1)N1CCC2(CC1)C(=O)N(c1ccc(F)c(Cl)c1)C2c1ccccn1 CHEMBL1210628 IC50 41.0 nM
O=C(Nc1cc(F)cc(F)c1)N1CCC2(CC1)CN(c1ccc(F)c(Cl)c1)C2c1ccccn1 CHEMBL1210564 IC50 41.0 nM
C[C@@H]1CN(Cc2cccc(C(F)(F)F)n2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3949063 IC50 42.0 nM
C[C@@H]1CN(Cc2cnc(C(F)(F)F)s2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3972616 IC50 42.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ccccc1OCCC(F)(F)F)CCC(C)(C)C2 CHEMBL4216897 IC50 42.0 nM
O=C1N(c2cccc(Cl)c2)C(c2ccccn2)C12CCN(c1nc3cc(F)c(C(F)(F)F)cc3[nH]1)CC2 CHEMBL1210899 IC50 44.0 nM
C[C@@H]1CN(CCOC(C)(C)C)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3939715 IC50 44.0 nM
C[C@@H]1CN(Cc2ccc(C(F)(F)F)o2)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3926060 IC50 44.0 nM
CC(C(=O)Nc1ccn(Cc2ccc(F)cc2)n1)c1ccc(N(C)C)cc1 CHEMBL4209751 IC50 44.0 nM
CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1)C(=O)OC CHEMBL1210267 IC50 45.0 nM
CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1)C(=O)OC(C)C CHEMBL1210370 IC50 45.0 nM
O=C(Nc1cccc(F)c1)N1N=C(c2ccc(Br)cc2)CC1c1ccc(F)cc1 CHEMBL3966141 IC50 46.0 nM
CN(C)c1ccc(CC(=O)Nc2ccn(Cc3ccc(F)c(F)c3)n2)cn1 CHEMBL4211393 IC50 46.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)C1CCOCC1 CHEMBL3979902 IC50 47.0 nM
COc1ccc(Cn2ccc(NC(=O)Cc3ccc(N(C)C)cc3)n2)cc1 CHEMBL4216279 IC50 47.0 nM
COc1ccc(CNC(=O)N2[C@H](C)CN(Cc3ccccc3)c3cnccc3[C@@H]2C)cc1 CHEMBL3956823 IC50 48.0 nM
C[C@@H]1CN(Cc2cccnc2F)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3978193 IC50 49.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)CN1CCOCC1 CHEMBL3984489 IC50 51.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cccc(F)c2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3984761 IC50 52.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cccc(F)c2[C@H](C)N1C(=O)CCc1cccnc1 CHEMBL3912958 IC50 52.0 nM
COc1ccc(C2=NN(C(=O)Nc3ccc(Cl)cc3)[C@](CCO)(c3cccnc3)C2)cc1 CHEMBL3966824 IC50 55.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)Cc1cncs1 CHEMBL3950196 IC50 55.0 nM
COc1ccc(CNC(=O)N2[C@H](C)CN(CCC(C)C)c3cnccc3[C@@H]2C)cc1 CHEMBL3910085 IC50 55.0 nM
CC(C)COc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CCC(C)(C)C2 CHEMBL4215580 IC50 55.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ncccc1N1CC[C@H](F)C1)CCC(C)(C)C2 CHEMBL4208356 IC50 56.0 nM
N#Cc1cccc(NC(=O)N2CCC3(CC2)C(=O)N(c2cccc(Cl)c2)C3c2ccccn2)c1 CHEMBL1210693 IC50 57.0 nM
COc1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1C CHEMBL4209075 IC50 57.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)N1CCOCC1 CHEMBL3977114 IC50 58.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cccc(F)c2[C@H](C)N1C(=O)NC1COC1 CHEMBL3926201 IC50 59.0 nM
O=C1N(c2ccc(F)c(Cl)c2)C(c2ccccn2)C12CCN(c1nc3cc(F)c(Cl)cc3[nH]1)CC2 CHEMBL1210901 IC50 60.0 nM
COCCOc1ccc(C2(CCO)CC(c3ccccc3)=NN2C(=O)Nc2ccc(F)cc2)cc1 CHEMBL3969496 IC50 60.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3889862 IC50 61.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NC1COC1 CHEMBL3898772 IC50 61.0 nM
Cc1sc(C(=O)NCc2ccccc2C(F)(F)F)c2c1[C@@H]1[C@H](C2)C1(C)C CHEMBL4202762 IC50 61.0 nM
C[C@@H]1CN(CC2CCCC2)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3915547 IC50 62.0 nM
CC(C)CCN1C[C@@H](C)N(C(=O)CCc2cccnc2)[C@@H](C)c2ccccc21 CHEMBL3916048 IC50 62.0 nM
CC(C)c1ccc(CC(=O)Nc2ccn(CCOCC(F)(F)F)n2)cc1 CHEMBL4210292 IC50 62.0 nM
CCOc1ccccc1CNC(=O)c1sc(Br)c2c1CCC(C)(C)C2 CHEMBL4215557 IC50 64.0 nM
Cn1c(C#N)c2c(c1C(=O)NCc1cccnc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4206268 IC50 65.0 nM
CC(C)CCN1C[C@@H](C)N(C(=O)CCc2cccnc2)[C@@H](C)c2c(F)cccc21 CHEMBL3921940 IC50 66.0 nM
O=C(Nc1ccccc1)N1N=C(c2ccc(Br)cc2)CC1c1ccc(F)cc1 CHEMBL3901517 IC50 68.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ncc(Cl)cc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3934795 IC50 68.0 nM
O=C(Nc1ccc(F)cc1)N1N=C(c2ccccc2)CC1(CO)c1ccc(F)cc1 CHEMBL3947301 IC50 70.0 nM
O=C1N(c2ccc(F)c(Cl)c2)C(c2ccccn2)C12CCN(c1nc3ccc(Cl)cc3[nH]1)CC2 CHEMBL1210900 IC50 71.0 nM
CN(C)c1ccc(CNC(=O)c2nc(Cc3ccc(F)c(F)c3)cs2)cc1 CHEMBL4210341 IC50 71.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cncc(F)c2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3933865 IC50 72.0 nM
C[C@@H]1CN(Cc2cccc(F)c2F)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3942836 IC50 72.0 nM
CC(C)(C)NC(=O)CN1CCC(CNC(=O)c2cc(F)cc(Cl)c2)CC1 CHEMBL3934636 IC50 73.0 nM
CC(C)c1ccc(CNC(=O)c2ccn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4203931 IC50 74.0 nM
CC(C)C(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)C[C@H](O)c2cc(F)ccc2[C@@H]1C(C)C CHEMBL3608943 IC50 76.0 nM
C[C@H](NC(=O)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1)c1ccc(F)cc1 CHEMBL1210442 IC50 82.0 nM
COc1cccc2nc(CCCN(C)CC[C@]3(OC(=O)C(C)C)C[C@H]4CCC[C@@H]3c3ccccc34)[nH]c12 CHEMBL3609819 IC50 84.0 nM
Cn1ncc2cc(CNC(=O)c3cnn(Cc4ccc(F)c(F)c4)n3)ccc21 CHEMBL4217691 IC50 90.0 nM
CC(C)CCN1C[C@@H](C)N(C(=O)Nc2cccnc2)[C@@H](C)c2ccccc21 CHEMBL3985310 IC50 91.0 nM
C[C@@H]1CN(CCOC(C)(C)C)c2ccccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3977684 IC50 91.0 nM
C[C@@H](NC(=O)Cc1ccc(C2CC2)cc1)c1ccc(OCC(F)(F)F)cn1 CHEMBL1684954 IC50 92.0 nM
C[C@@H]1CN(Cc2cnc(C(F)(F)F)s2)c2cccc(F)c2[C@H](C)N1C(=O)CCc1cccnc1 CHEMBL3930876 IC50 93.0 nM
O=c1n(CCCCc2cccc(F)c2)c2ccccc2n1C1CCN(CCCCc2cccc(F)c2)CC1 CHEMBL5399702 IC50 93.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ncc(F)cc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3925915 IC50 95.0 nM
C[C@@H]1CN(Cc2ccccc2F)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3972450 IC50 95.0 nM
O=C(NCc1ccc(C2(F)COC2)cc1)c1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4213283 IC50 100.0 nM
CN(C)c1ccc(CNC(=O)c2csc(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4205450 IC50 100.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cnccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3895005 IC50 102.0 nM
CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)CN(C(C)C)C2c1ccc(Cl)cc1)C(=O)OC CHEMBL1210027 IC50 104.0 nM
C[C@@H]1CN(Cc2ccccc2)c2nc(C(F)(F)F)ccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3916909 IC50 104.0 nM
CC(C)C(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)C[C@@H](O)c2cc(F)ccc2[C@@H]1C(C)C CHEMBL3608942 IC50 107.0 nM
CN(CC(=O)Nc1cccc(S(=O)(=O)N(Cc2ccccc2)c2cccc(Cl)c2)c1)C(=O)OCc1ccccc1 CHEMBL403689 IC50 110.0 nM
O=C(Nc1ccc(F)cc1)N1N=C(c2cc[n+]([O-])cc2)CC1c1ccc(F)cc1 CHEMBL3893662 IC50 110.0 nM
Cn1c(Cl)c2c(c1C(=O)NCc1ccncc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4204013 IC50 110.0 nM
Cn1c(C(=O)NCc2cccnc2OCC(F)(F)F)c2c(c1C(F)(F)F)CC(C)(C)CC2 CHEMBL4211150 IC50 110.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccc(F)cc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3914936 IC50 112.0 nM
CC(C)C(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)C[C@H](OCc2ccccc2)c2cc(F)ccc2[C@@H]1C(C)C CHEMBL3608316 IC50 113.0 nM
O=C(Nc1ccc(F)c(F)c1)N1CCC2(CC1)C(=O)N(c1cccc(Cl)c1)C2c1ccccn1 CHEMBL1210692 IC50 116.0 nM
O=C(Nc1ccc(F)cc1)N1N=C(c2ccccc2)CC1(CCO)c1ccccc1 CHEMBL3946972 IC50 120.0 nM
Cn1cnc2ccc(CC(=O)Nc3ccn(Cc4ccc(F)c(F)c4)n3)cc21 CHEMBL4211522 IC50 120.0 nM
CC(C)C(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)C[C@@H](OCc2ccccc2)c2cc(F)ccc2[C@@H]1C(C)C CHEMBL3608941 IC50 132.0 nM
CC(C)N1CC2(CCN(C(=O)Nc3cc(F)cc(F)c3)CC2)C1c1ccc(Cl)cc1 CHEMBL1210081 IC50 138.0 nM
C[C@H](NC(=O)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1)c1ccccc1 CHEMBL1209965 IC50 139.0 nM
COc1ccc(C2(CCO)CC(c3cccnc3)=NN2C(=O)Nc2ccc(Br)cc2)cc1 CHEMBL3898970 IC50 140.0 nM
CC(C)c1ccc(CC(=O)NC(C)c2ccn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4206470 IC50 140.0 nM
O=C(Cc1ccc(OCC(F)(F)F)nc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4214341 IC50 140.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2CN1C(=O)NCc1ccccc1 CHEMBL3959377 IC50 141.0 nM
CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)CN(c1cccc(F)c1)C2c1ccc(Cl)cc1)C(=O)OC CHEMBL1210266 IC50 146.0 nM
CC(C)C(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CCc2cc(F)ccc2[C@@H]1C(C)C CHEMBL3609822 IC50 149.0 nM
O=c1n(CCCCc2ccccc2)c2ccccc2n1C1CCN(CCCCc2cccc(F)c2)CC1 CHEMBL5430690 IC50 151.0 nM
O=C(CCCc1ccccc1)N1CCC(n2c(=O)n(CCCCc3ccccc3)c3ccccc32)CC1 CHEMBL5399421 IC50 153.0 nM
O=C(Cc1ccc(OC(F)(F)F)cc1)Nc1ccn(Cc2ccccc2)n1 CHEMBL4215146 IC50 155.0 nM
O=c1[nH]c2ccccc2n1C1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 CHEMBL1423 IC50 157.0 nM
CCOCc1ccc(CNC(=O)c2sc(C)c3c2C[C@H]2[C@@H]3C2(C)C)cc1 CHEMBL4209762 IC50 160.0 nM
CN(C)c1ccc(Cc2nc3cn(Cc4ccc(F)cc4)nc3[nH]2)cc1 CHEMBL4205371 IC50 160.0 nM
CC(C)c1ccc(CC(=O)NCc2ccn(Cc3ccc(F)c(F)c3)n2)cc1 CHEMBL4209235 IC50 160.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(Cc2ccccc2)c(-c2ccccc2)c1C(F)F CHEMBL4209062 IC50 170.0 nM
CC(C)N1CC2(CCN(C(=O)Nc3cc(F)cc(F)c3)CC2)C1c1ccc(F)cc1 CHEMBL1210203 IC50 172.0 nM
CC(C)N1CC2(CCN(C(=O)Nc3ccc(F)c(F)c3)CC2)C1c1ccc(Cl)cc1 CHEMBL1210080 IC50 174.0 nM
CC(C)CN1CC2(CCN(C(=O)Nc3cc(F)cc(F)c3)CC2)C1c1ccc(Cl)cc1 CHEMBL1210140 IC50 177.0 nM
CC(C)CCCN(c1cccc(Cl)c1)S(=O)(=O)c1cccc(NC(=O)CN(C)C(=O)OCc2ccccc2)c1 CHEMBL269980 IC50 180.0 nM
CC1=C(C(=O)OC(C)C)C(c2cccc(Cl)c2)N(CCCN(C)C(=O)c2ccc(Oc3ccccc3)cc2)C(=O)N1 CHEMBL257288 IC50 180.0 nM
CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1)C(=O)NC CHEMBL1210371 IC50 182.0 nM
N#Cc1cccc(NC(=O)N2CCC3(CC2)C(=O)N(c2cccc(F)c2)C3c2ccc(Cl)cc2)c1 CHEMBL1210506 IC50 183.0 nM
CC(C)C(=O)O[C@@]1(CCN(C)CCCc2nc3ccccc3[nH]2)C[C@H]2CCC[C@@H]1c1ccccc12 CHEMBL3609818 IC50 184.0 nM
Cc1ccccc1Cn1ccc(NC(=O)Cc2ccc(N(C)C)cc2)n1 CHEMBL4217744 IC50 190.0 nM
CCCC[C@@H]1C[C@@](CCN(C)CCCc2nc3ccccc3[nH]2)(OC(=O)COC)[C@@H](C(C)C)c2ccc(F)cc21 CHEMBL3609824 IC50 193.0 nM
CC1(C)C[C@@H](CN2CCC(F)(CNC(=O)c3cc(Cl)cc(Cl)c3)CC2)CCO1 CHEMBL488817 Activity 196.0 nM
C[C@@H]1CN(C(=O)NCc2ccccc2)[C@@H](C)c2ccccc2N1Cc1ccccc1 CHEMBL3904762 IC50 198.0 nM
O=C(Nc1ccncc1)N1N=C(c2ccccc2)CC1c1ccc(F)cc1 CHEMBL3960151 IC50 202.0 nM
C[C@@H]1CN(Cc2ccccc2)c2c(F)cccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3908881 IC50 205.0 nM
COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)CC(C)(C)c2cc(F)ccc2[C@@H]1C(C)C CHEMBL3609823 IC50 207.0 nM
C[C@@H]1CN(c2ccccc2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3969267 IC50 209.0 nM
CN(CCCc1nc2ccccc2[nH]1)CC[C@@]1(OC(=O)C2CC2)C[C@@H]2CC[C@H]1c1ccccc12 CHEMBL3608946 IC50 210.0 nM
CCOc1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1 CHEMBL4203473 IC50 210.0 nM
Cc1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1 CHEMBL4212175 IC50 210.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cccnc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3963167 IC50 212.0 nM
CN1CC2(CCN(C(=O)Nc3cc(F)cc(F)c3)CC2)C1c1ccc(Cl)cc1 CHEMBL1210137 IC50 214.0 nM
CC(C)C(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)C[C@@H]2CCC[C@H]1c1ccccc12 CHEMBL3608947 IC50 217.0 nM
Cn1nc(C(=O)NCc2ccccc2OCC(F)(F)F)c(Br)c1-c1ccccc1 CHEMBL4215680 IC50 220.0 nM
O=C(Cc1ccc(C2CC2)nc1)Nc1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4202684 IC50 220.0 nM
CC[C@H](NC(=O)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1)c1ccccc1 CHEMBL1209967 IC50 224.0 nM
CO[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)C[C@@H]2CC[C@H]1c1ccccc12 CHEMBL3609820 IC50 224.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cnc(Cl)cc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3986638 IC50 224.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cnccc2[C@H](C)N1C(=O)CCc1ccc(F)cc1 CHEMBL3951580 IC50 225.0 nM
[2H]C([2H])(c1ccccc1)N1C[C@@H](C)N(C(=O)NCc2ccccc2)[C@@H](C)c2ccncc21 CHEMBL3980491 IC50 230.0 nM
Cc1ccc2c(c1)N(Cc1ccccc1)C[C@@H](C)N(C(=O)Nc1cccnc1)[C@H]2C CHEMBL3903942 IC50 231.0 nM
CC(C)OC(=O)CN(c1cccc(Cl)c1)S(=O)(=O)c1cccc(NC(=O)CN(C)C(=O)OCc2ccccc2)c1 CHEMBL272128 IC50 240.0 nM
Cc1ccc(C2(CCN(C)C)CC(c3ccccc3)=NN2C(=O)Nc2ccc(F)cc2)cc1 CHEMBL3930559 IC50 240.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cncc(F)c2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3898062 IC50 240.0 nM
CC(C)COc1ccccc1CNC(=O)c1c(Cl)c(C2CC2)c(Cl)n1C CHEMBL4209272 IC50 240.0 nM
C[C@H]1c2ccccc2N(Cc2ccccc2)CCN1C(=O)NCc1ccccc1 CHEMBL3890307 IC50 241.0 nM
N#Cc1cccc(N2C(=O)C3(CCN(C(=O)Nc4cc(F)cc(F)c4)CC3)C2c2ccccn2)c1 CHEMBL1209968 IC50 247.0 nM
COC(=O)[C@H](COC(C)(C)C)NC(=O)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1 CHEMBL1210372 IC50 251.0 nM
CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)CN(C(C)C)C2c1ccc(F)cc1)C(=O)OC CHEMBL1210202 IC50 256.0 nM
CC(C)c1ccc(Cc2nnc(-c3ccn(Cc4ccc(F)c(F)c4)n3)[nH]2)cc1 CHEMBL4213632 IC50 260.0 nM
CCC(=CCc1c(O)cc2c(c1O)C(=O)CC(c1ccc(O)cc1)O2)CC CHEMBL4248823 IC50 260.0 nM
O=C(CC1c2ccccc2N=C(SCCCCCN2CCCC2)N1c1ccc(-c2ccc(F)cc2)cc1)NCc1ccccc1 CHEMBL4642980 IC50 260.0 nM
CCNCCc1c(C(=O)NCc2ccccc2OCC(F)(F)F)nn(-c2ccccc2)c1-c1ccccc1 CHEMBL4209001 IC50 280.0 nM
O=C(Cc1ccc(Cl)cc1)Nc1ccn(Cc2ccccc2)n1 CHEMBL4206874 IC50 280.0 nM
Fc1ccc(NC(=S)N2N=C(c3ccc(Br)cc3)CC2c2ccc(F)cc2)cc1 CHEMBL3897833 IC50 281.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2F)c(C2CC2)c1Br CHEMBL4204051 IC50 290.0 nM
CC(C)(C)NC(=O)NCCN1CCN(CC(=O)Nc2cc(Cl)cc(Cl)c2)CC1 CHEMBL2338405 IC50 300.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2F)c(-c2ccccc2)c1Br CHEMBL4209876 IC50 300.0 nM
COc1cccc2c1[C@H](C)N(C(=O)Nc1cccnc1)[C@H](C)CN2Cc1ccccc1 CHEMBL3917820 IC50 305.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1CCO CHEMBL4213393 IC50 310.0 nM
CC(C)(C)CCN1CC2C(CNC(=O)c3cc(Cl)cc(Cl)c3)C2C1 CHEMBL4535646 IC50 310.0 nM
O=C(NC1CCCCC1)N1N=C(c2ccc(Br)cc2)CC1c1ccc(F)cc1 CHEMBL3942685 IC50 316.0 nM
CO[C@H]1C[C@@](CCN(C)CCCc2nc3ccccc3[nH]2)(OC(=O)C(C)C)[C@@H](C(C)C)c2ccc(F)cc21 CHEMBL3608940 IC50 318.0 nM
O=C(Nc1ccc(F)cc1)N1N=C(c2ccncc2)C[C@@H]1c1ccc(F)cc1 CHEMBL3920575 IC50 320.0 nM
CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)CN(C1CC1)C2c1ccc(Cl)cc1)C(=O)OC CHEMBL1210984 IC50 325.0 nM
Cc1ccc(C2(CCO)CC(c3ccncc3)=NN2C(=O)Nc2ccc(F)cc2)cc1 CHEMBL3910259 IC50 330.0 nM
Cn1cc2c(c1C(=O)NCc1cccnc1OCC(F)(F)F)CCC(C)(C)C2 CHEMBL4203828 IC50 330.0 nM
O=C(NCc1ccc2[nH]ccc2c1)c1ccn(Cc2ccc(F)c(F)c2)n1 CHEMBL4208810 IC50 330.0 nM
C[C@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3978731 IC50 340.0 nM
CCOC(=O)C1=C(C)NC(=O)N(CCC(=O)NNC(=S)NC(c2ccccc2)c2ccccc2)C1c1cccc([N+](=O)[O-])c1 CHEMBL4077901 IC50 340.0 nM
CC(C)Oc1ccccc1CNC(=O)c1sc(Br)c2c1CCC(C)(C)C2 CHEMBL4206884 IC50 340.0 nM
CC(C)C(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)C[C@@H]2CC[C@H]1c1ccccc12 CHEMBL3608945 IC50 350.0 nM
COCC1(c2ccc(C)cc2)CC(c2ccccc2)=NN1C(=O)Nc1ccc(F)cc1 CHEMBL3941425 IC50 350.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1Br CHEMBL4206919 IC50 350.0 nM
C[C@@H](NC(=O)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1)c1ccccc1 CHEMBL1209966 IC50 351.0 nM
C[C@@H]1c2ccccc2N(Cc2ccccc2)C[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3951718 IC50 358.0 nM
COCC(=O)O[C@]1(CCN(C)CCCc2nc3ccccc3[nH]2)C[C@@H]2CC[C@H]1c1ccccc12 CHEMBL3608944 IC50 361.0 nM
Cn1nc(C(=O)NCc2ccccc2OCC(F)(F)F)c(C(F)F)c1-c1ccccc1 CHEMBL4211471 IC50 370.0 nM
Cc1sc(C(=O)NCc2cccc(OC(F)(F)F)c2)c2c1[C@@H]1[C@H](C2)C1(C)C CHEMBL4214944 IC50 370.0 nM
CC(C)COc1ccccc1CNC(=O)c1c2c(c(Cl)n1C)CN(C(=O)OC(C)(C)C)C2 CHEMBL4206782 IC50 370.0 nM
CCc1c(Br)c(C(=O)NCc2ccccc2OCC(F)(F)F)nn1-c1ccccc1 CHEMBL4215724 IC50 380.0 nM
O=C(NCc1ncccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1Br CHEMBL4203516 IC50 380.0 nM
CC(C)NC(=O)N1N=C(c2ccc(Br)cc2)CC1c1ccc(F)cc1 CHEMBL3923714 IC50 382.0 nM
O=C(Nc1cc(F)cc(F)c1)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1 CHEMBL1210505 IC50 390.0 nM
CCC(=CCc1c(O)cc2c(c1O)C(=O)CC(c1ccccc1O)O2)CC CHEMBL4249364 IC50 390.0 nM
O=C(NCc1ccccc1)N1CCN(Cc2ccccc2)c2ccccc2C1 CHEMBL3979642 IC50 392.0 nM
O=C(Nc1ccccn1)N1N=C(c2ccc(Br)cc2)CC1c1ccc(F)cc1 CHEMBL3969020 IC50 393.0 nM
O=C(Nc1cc(F)cc(F)c1)N1CCC2(CC1)CN(C1CC1)C2c1ccc(Cl)cc1 CHEMBL1210205 IC50 398.0 nM
CC(C)C(=O)O[C@@]1(CCN(C)CCCc2nc3ccccc3[nH]2)C[C@H]2CC[C@@H]1c1ccccc12 CHEMBL3609817 IC50 398.0 nM
CC(C)(C)NC(=O)NCCN1CCC(CNC(=O)c2cc(Cl)cc(Cl)c2)C1 CHEMBL2338409 IC50 400.0 nM
O=C(NCc1ccccc1-n1cccn1)c1nn(-c2ccccc2)c(-c2ccccc2)c1Br CHEMBL4208390 IC50 400.0 nM
CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)CN(C)C2c1ccc(Cl)cc1)C(=O)OC CHEMBL1210136 IC50 410.0 nM
CN1CC2(CCN(C(=O)Nc3cc(F)cc(F)c3)CC2)C1c1ccc(F)cc1 CHEMBL1210204 IC50 410.0 nM
CC1CC(c2ccccc2)=NN1C(=O)Nc1ccc(F)cc1 CHEMBL3973610 IC50 410.0 nM
CS(=O)(=O)c1ccc(C2CC(c3ccncc3)=NN2C(=O)Nc2ccc(F)cc2)cc1 CHEMBL3919508 IC50 410.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccc(F)cc2)c(-c2ccccc2)c1Br CHEMBL4206356 IC50 410.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1CO CHEMBL4211289 IC50 410.0 nM
COc1cc2c(cc1F)N(Cc1ccccc1)C[C@@H](C)N(C(=O)Nc1cccnc1)[C@H]2C CHEMBL3899835 IC50 414.0 nM
CC(C)OC(=O)CN(c1cccc(Cl)c1)S(=O)(=O)c1cccc(NC(=O)CCNC(=O)OCc2ccccc2)c1 CHEMBL272127 IC50 420.0 nM
O=C(NCCc1ccccc1)N1N=C(c2ccc(Br)cc2)CC1c1ccc(F)cc1 CHEMBL3932660 IC50 420.0 nM
CS(=O)(=O)c1ccc(C2(CCO)CC(c3ccccc3)=NN2C(=O)Nc2ccc(F)cc2)cc1 CHEMBL3937064 IC50 420.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cc(Br)ccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3974104 IC50 428.0 nM
Cc1ccc(C2(CCN3CCOCC3)CC(c3ccccc3)=NN2C(=O)Nc2ccc(F)cc2)cc1 CHEMBL3902564 IC50 430.0 nM
COc1ccc(NC(=O)N2N=C(c3ccc(Br)cc3)CC2c2ccc(F)cc2)cc1 CHEMBL3933724 IC50 447.0 nM
O=C1CC(c2ccc(O)cc2)Oc2cc(O)c(CC=C3CCCC3)c(O)c21 CHEMBL4238346 IC50 460.0 nM
O=c1n(CCCCc2ccccc2)c2ccccc2n1C1CCN(CCCCc2ccccc2)CC1 CHEMBL5396601 IC50 461.0 nM
C[C@H]1c2ccccc2N(Cc2ccccc2)[C@@H](C)CN1C(=O)NCc1ccccc1 CHEMBL3950664 IC50 464.0 nM
COCc1ccc(CNC(=O)c2sc(Br)c3c2CCC(C)(C)C3)cc1 CHEMBL4217576 IC50 470.0 nM
C[C@@H]1CN(Cc2ccccn2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3976890 IC50 479.0 nM
CC(C)CCc1c(O)cc2c(c1O)C(=O)CC(c1ccc(O)cc1)O2 CHEMBL4251381 IC50 480.0 nM
CC(C)(C)NC(=O)NCCN1CCCC(NC(=O)c2cc(Cl)cc(Cl)c2)C1 CHEMBL2337979 IC50 500.0 nM
CC(C)(C)NC(=O)NCCN1CCCC(CNC(=O)c2cc(Cl)cc(Cl)c2)C1 CHEMBL2338407 IC50 500.0 nM
CC(C)(C)NC(=O)NCCN1CCC(CNC(=O)c2cc(Cl)cc(Cl)c2)CC1 CHEMBL2338406 IC50 500.0 nM
CC(C)(C)NC(=O)NCCN1CCN(CC(=O)NC23CC4CC(CC(C4)C2)C3)CC1 CHEMBL2338400 IC50 500.0 nM
C[C@@H]1CN(Cc2cccnc2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3950824 IC50 500.0 nM
O=C1CC(c2ccc(O)cc2)Oc2cc(O)c(CCC3CCCC3)c(O)c21 CHEMBL4240812 IC50 500.0 nM
O=C(NCc1ccccc1)c1cc(-c2ccccc2)n(-c2ccccc2)n1 CHEMBL4216796 IC50 510.0 nM
O=C(Nc1cc(F)cc(F)c1)N1CCC2(CC1)C(=O)N(c1cncc(Cl)c1)C2c1ccccn1 CHEMBL1210835 IC50 519.0 nM
COc1ccc2c(c1)[C@H](C)N(C(=O)Nc1cccnc1)[C@H](C)CN2Cc1ccccc1 CHEMBL3925393 IC50 530.0 nM
Cc1sc(C(=O)NCc2cccc(C(F)(F)F)c2)c2c1[C@@H]1[C@H](C2)C1(C)C CHEMBL4203292 IC50 530.0 nM
CC(C)OC(=O)CN(c1cccc(Cl)c1)S(=O)(=O)c1cccc(NC(=O)CCc2ccccc2)c1 CHEMBL402197 IC50 540.0 nM
CO[C@@H]1C[C@@](CCN(C)CCCc2nc3ccccc3[nH]2)(OC(=O)C(C)C)[C@@H](C(C)C)c2ccc(F)cc21 CHEMBL3609825 IC50 557.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2cccc(F)c2)c(-c2ccccc2)c1Br CHEMBL4211241 IC50 580.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1CCNC1CC1 CHEMBL4205063 IC50 590.0 nM
CC(C)(C)NC(=O)NCCN1CCC(CO)(CNC(=O)c2cc(Cl)cc(Cl)c2)CC1 CHEMBL2337981 IC50 600.0 nM
CC(C)(C)NC(=O)NCCN1CCC(O)(CNC(=O)c2cc(Cl)cc(Cl)c2)CC1 CHEMBL2337980 IC50 600.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(CC(F)(F)F)c(-c2ccccc2)c1C(F)F CHEMBL4207289 IC50 600.0 nM
O=C(NCc1cccnc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1Br CHEMBL4211809 IC50 600.0 nM
CC(C)CCN1C[C@@H](C)N(C(=O)Nc2cccnc2)[C@@H](C)c2ccncc21 CHEMBL3927924 IC50 604.0 nM
COc1ccc(CC(=O)Nc2ccn(Cc3ccccc3)n2)cc1 CHEMBL4210726 IC50 610.0 nM
CCc1ccc(NC(=O)N2N=C(c3ccc(Br)cc3)CC2c2ccc(F)cc2)cc1 CHEMBL3914689 IC50 613.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2C(=O)N1CCc1ccccc1 CHEMBL3970445 IC50 618.0 nM
CC(C)=CCc1c(O)cc2c(c1O)C(=O)CC(c1ccccc1O)O2 CHEMBL4245811 IC50 640.0 nM
Cc1sc(C(=O)NCc2ccccc2Cl)c2c1[C@@H]1[C@H](C2)C1(C)C CHEMBL4207112 IC50 670.0 nM
C[C@@H]1C(=O)N(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3899264 IC50 682.0 nM
Cc1ccc(C2(CCN3CCN(C)CC3)CC(c3ccccc3)=NN2C(=O)Nc2ccc(F)cc2)cc1 CHEMBL3893591 IC50 690.0 nM
C[C@@H]1CN(Cc2ccccc2)c2nnccc2[C@H](C)N1C(=O)NCc1ccccc1 CHEMBL3961356 IC50 695.0 nM
O=C(Nc1ccc(F)c(F)c1)N1CCC2(CC1)C(=O)N(c1cccc(Cl)c1)C2c1cccc[n+]1[O-] CHEMBL1210767 IC50 698.0 nM
O=C(Cc1cccc(Cl)c1)Nc1ccn(Cc2ccccc2)n1 CHEMBL4211644 IC50 750.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cc(OCC(F)(F)F)ccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3974827 IC50 790.0 nM
CC[C@H](C)[C@H](NC(=O)N1CCC2(CC1)C(=O)N(C)C2c1ccc(Cl)cc1)C(=O)OC CHEMBL1210138 IC50 800.0 nM
CC(C)(C)NC(=O)NCCN1CCC(NC(=O)c2cc(Cl)cc(Cl)c2)C1 CHEMBL2337978 IC50 800.0 nM
CC(C)(C)NC(=O)NCCN1CC(NC(=O)c2cc(Cl)cc(Cl)c2)C1 CHEMBL2337977 IC50 800.0 nM
[2H]C([2H])(c1ccccc1)N1C[C@@H](C)N(C(=O)Nc2cccnc2)[C@@H](C)c2ccncc21 CHEMBL3919009 IC50 815.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(-c2ccccc2)c(-c2ccccc2)c1C(F)F CHEMBL4204992 IC50 820.0 nM
COC(=O)[C@H](C)NC(=O)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1 CHEMBL1210985 IC50 827.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)N(C)Cc1ccccc1 CHEMBL3951240 IC50 835.0 nM
C[C@@H]1CN(Cc2ccccc2)c2ccccc2[C@H](C)N1C(=O)OCc1ccccc1 CHEMBL3936568 IC50 841.0 nM
C=Cc1c(C(=O)NCc2ccccc2OCC(F)(F)F)nn(-c2ccccc2)c1-c1ccccc1 CHEMBL4216669 IC50 850.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cc(C#N)ccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3944657 IC50 860.0 nM
C[C@@H]1CN(Cc2ccccc2)c2cnccc2[C@H](C)N1C(=O)Nc1cccnc1 CHEMBL3917185 IC50 860.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1nn(CC(F)(F)F)c(-c2ccccc2)c1Br CHEMBL4210724 IC50 890.0 nM
CC(C)(C)CS(=O)(=O)NCCN1CCN(CC(=O)NC23CC4CC(CC(C4)C2)C3)CC1 CHEMBL2338404 IC50 900.0 nM
CC1=NN(C(=O)Nc2ccc(F)cc2)C(c2ccc(F)cc2)C1 CHEMBL3911637 IC50 900.0 nM
CN1C(=O)C2(CCN(C(=O)Nc3cc(F)cc(F)c3)CC2)C1c1ccc(Cl)cc1 CHEMBL1210139 IC50 920.0 nM
CCN1C[C@@H](C)N(C(=O)NCc2ccccc2)[C@@H](C)c2ccccc21 CHEMBL3950065 IC50 922.0 nM
Cc1ccccc1CNC(=O)c1sc(C)c2c1C[C@H]1[C@@H]2C1(C)C CHEMBL4207625 IC50 990.0 nM
CC(C)(C)NC(=O)CN1CCN(CC(=O)NC23CC4CC(CC(C4)C2)C3)CC1 CHEMBL2337984 IC50 1000.0 nM
O=C(NCc1ccccc1OCC(F)(F)F)c1cc(-c2ccccc2)n(-c2ccccc2)n1 CHEMBL4212371 IC50 1000.0 nM
C=C(C)[C@H](CC=C(C)C)Cc1c(O)cc(O)c2c1O[C@H](c1ccc(O)cc1O)CC2=O CHEMBL243148 IC50 1000.0 nM
CC(C)=CCc1c(O)cc(O)c2c1O[C@H](c1ccc(O)cc1)CC2=O CHEMBL376915 IC50 1000.0 nM
CC(C)=CCc1c(O)cc2c(c1O)C(=O)CC(c1ccc(O)cc1)O2 CHEMBL1537093 IC50 1000.0 nM