CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CNc1ccc2oc(-c3ccc(N(C)C)cc3)nc2c1)C(C)C CHEMBL4751195 Ki 0.08 nM
CCCCCN(C)CNCC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1cc(C(C)(C)C)nc(NCc2nonc2C)c1=O CHEMBL180669 IC50 0.1 nM
O=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL213759 Ki 0.2 nM
CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H](C=O)CC(=O)O)C(C)C CHEMBL417149 IC50 0.2 nM
CC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1cccc(NC(=O)[C@H](CC(=O)O)NC(C)=O)c1=O CHEMBL178116 IC50 0.3 nM
O=C1C(=O)N(Cc2cn(CCF)nn2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccc(F)cc3F)cc21 CHEMBL456799 EC50 0.5 nM
CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CCCc1ccccc1)C(C)C CHEMBL443565 IC50 0.771 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(OCCOS(=O)(=O)c2ccc(C)cc2)cc1 CHEMBL216071 Ki 0.8 nM
O=C(Nc1ccc(N2CCOCC2)cc1)n1sc2ccccc2c1=O CHEMBL3233630 IC50 1.15 nM
CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H]1CC(=O)OC1O)C(C)C CHEMBL430648 IC50 1.2 nM
O=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL439753 Ki app 1.2 nM
O=C1C(=O)N(Cc2ccc(I)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL384023 Ki 1.2 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2C CHEMBL216819 Ki 1.2 nM
O=C1C2=NCC3(CCC3)CN2c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL595807 IC50 1.29 nM
CCCCCN(C)CC(=O)C(CC(=O)O)NC(=O)C(CC)n1cc(C(C)(C)C)nc(NCc2nonc2C)c1=O CHEMBL179503 Ki 1.4 nM
CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)c1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)CCCc1ccccc1 CHEMBL352426 IC50 1.8 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(O[Si](C)(C)C(C)(C)C)cc1 CHEMBL387041 Ki 1.9 nM
CC(C)C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)OCc1ccccc1)C(=O)N[C@H]1CC(=O)OC1O CHEMBL100588 IC50 2.3 nM
O=C1C(=O)N(Cc2ccc(F)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COC3CCOCC3)cc21 CHEMBL456593 EC50 2.3 nM
O=C1C2=NCC3(CCCC3)CN2c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL594384 IC50 2.32 nM
CN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)ccc21 CHEMBL293034 IC50 2.4 nM
CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4cccnc4)ccc3N2C1 CHEMBL606626 IC50 2.4 nM
COC[C@@H]1CCCN1S(=O)(=O)c1cc(Br)c2c(c1)C(=O)C(=O)N2CCCCO CHEMBL3359197 IC50 2.6 nM
CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COC)cc(F)c21 CHEMBL3359202 IC50 2.9 nM
CC(C)(C)OC(=O)CN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)ccc21 CHEMBL60671 pIC50 2.999 nM
COC(=O)C[C@H](NC(C)=O)C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)C3 CHEMBL420407 IC50 3.0 nM
CCn1nc(-c2ccc(OC)cc2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL2086889 IC50 3.0 nM
O=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL1762353 IC50 3.1 nM
O=C1C(=O)N(Cc2ccccc2[N+](=O)[O-])c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133146 IC50 3.1 nM
CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@H](C=O)CC(=O)O)C(C)C CHEMBL225647 Ki 3.2 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C1=NCC3(CCC3)CN12 CHEMBL603644 IC50 3.3 nM
COc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CC[C@H]4COc4cccnc4)ccc32)cc1 CHEMBL1762350 IC50 3.3 nM
CC(=O)N[C@@H](C(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H]1CC(=O)OC1O)C(C)C CHEMBL328412 IC50 3.5 nM
O=C1C(=O)N(Cc2ccc(Br)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL227036 IC50 3.6 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCC(O)CF CHEMBL493375 IC50 3.6 nM
O=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3cccnc3)cc21 CHEMBL1762349 IC50 3.6 nM
CC(C)CC(NC(=O)[C@H](CCC(=O)O)Oc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O CHEMBL101545 IC50 3.8 nM
O=C1C(=O)N(Cc2ccc(O)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL227035 pIC50 3.89 nM
COc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4cccnc4)ccc32)cc1 CHEMBL372322 pIC50 3.89 nM
Cc1nc2ccc(S(=O)(=O)N3CCOCC3)cc2c2c1C(=O)N(c1c(C)nn(C)c1C)C2=O CHEMBL360360 IC50 4.0 nM
O=C1C(=O)N(Cc2ccc(O)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL200927 Ki 4.0 nM
O=C1C(=O)N(Cc2ccncc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL300369 pIC50 4.198 nM
CSc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4cccnc4)ccc32)cc1 CHEMBL198755 pIC50 4.365 nM
O=C1C(=O)N(Cc2nnnn2Cc2ccccc2)c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133149 IC50 4.4 nM
CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4cncc(Cl)c4)ccc3N2C1 CHEMBL593476 IC50 4.43 nM
O=C1C(=O)N(Cc2cn(CCF)nn2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL1762363 IC50 4.5 nM
C=CCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)ccc21 CHEMBL64219 IC50 4.6 nM
CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COCCF)ccc21 CHEMBL2348701 IC50 4.79 nM
COc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4ccccc4)ccc32)cc1 CHEMBL200677 Ki 4.8 nM
COC[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)c2c(c1)C(=O)C(=O)N2CCCF CHEMBL3359200 IC50 4.8 nM
CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4CN4CCOCC4)ccc3N2C1 CHEMBL593222 IC50 4.99 nM
CCOc1ccc(OCC(=O)O)cc1CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1c(F)cccc1Cl)C(C)C CHEMBL167882 IC50 5.0 nM
COc1ccc(S(C)(=O)=O)cc1CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1c(F)cccc1Cl)C(C)C CHEMBL166754 IC50 5.0 nM
COc1ccc(S(C)(=O)=O)cc1CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)C(C)C CHEMBL425699 IC50 5.0 nM
CCCCCCN(C)CC(=O)C(CC(=O)O)NC(=O)C(CC)n1cc(C(C)(C)C)nc(NCc2nonc2C)c1=O CHEMBL366927 Ki 5.0 nM
CC(C)[C@H](OC(=O)Nc1cc(Cl)ccc1Cl)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL181241 IC50 5.0 nM
COc1ccc(Br)cc1[C@@H](O)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)C(C)C CHEMBL183379 IC50 5.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CCCc1ccccc1)n1cc(C(C)(C)C)nc(Nc2nnn[nH]2)c1=O CHEMBL248508 IC50 5.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(Br)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL387556 IC50 5.1 nM
O=C1C(=O)N(CC2CCCCC2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL64895 IC50 5.2 nM
O=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL197549 IC50 5.2 nM
CCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COC)ccc21 CHEMBL493926 IC50 5.3 nM
O=C1C(=O)N(Cc2ccc(F)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccncn3)cc21 CHEMBL515506 EC50 5.5 nM
O=C1C(=O)N(Cc2cn(CCF)nn2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3cccnc3)cc21 CHEMBL1762362 IC50 5.6 nM
O=C1C(=O)N(Cc2cccc(F)n2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL371687 pIC50 5.754 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(I)cc1 CHEMBL217457 Ki 5.9 nM
CCCCCCN(C)CNCC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1cc(C(C)(C)C)nc(NCc2nonc2C)c1=O CHEMBL361825 IC50 6.0 nM
CCCCCCN(C)CNCC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1cc(CC)nc(NCc2nonc2C)c1=O CHEMBL369290 IC50 6.0 nM
CC(C)[C@H](OC(=O)Nc1cccc(F)c1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL181719 IC50 6.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C1=NCC(C)(C)CN12 CHEMBL594873 IC50 6.0 nM
COc1ccc(CN2C(=O)C(=C(C#N)C#N)c3cc(S(=O)(=O)N4CC[C@H]4COc4cccnc4)ccc32)cc1 CHEMBL1762357 IC50 6.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)C2CC2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4228386 IC50 6.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)C2CCC2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4224765 IC50 6.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)C2CCCC2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4225291 IC50 6.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL197672 IC50 6.0 nM
CCCCCCN(C)CC(=O)C(CC(=O)O)NC(=O)[C@H](CC)n1cc(C(C)(C)C)nc(NCc2nonc2C)c1=O CHEMBL5280661 IC50 6.0 nM
O=C1C(=O)N(Cc2ccc(Br)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133253 IC50 6.2 nM
O=C1C(=O)N(Cc2ccc([N+](=O)[O-])cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133148 IC50 6.3 nM
CCCCCCN(C)CC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1cc(C(C)(C)C)nc(Nc2nnn[nH]2)c1=O CHEMBL248310 IC50 6.6 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(C2CO2)cc1 CHEMBL523666 IC50 6.6 nM
CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4ccccc4)ccc3N2C1 CHEMBL592983 IC50 7.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)c2cccs2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4228658 IC50 7.0 nM
CC(C)[C@H](NC(=O)COc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1cccc2ccccc12 CHEMBL118738 Ki 7.1 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3cccnc3)cc21 CHEMBL1762356 IC50 7.1 nM
O=C1C(=O)N(Cc2ccc(Cl)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133254 IC50 7.1 nM
Cc1ncccc1OC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C1=NCC(C)(C)CN12 CHEMBL593714 IC50 7.18 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL1762360 IC50 7.5 nM
N#CC(C#N)=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL226828 IC50 7.6 nM
COc1ccc(CN2C(=O)C(=C(C#N)C#N)c3cc(S(=O)(=O)N4CCC[C@H]4COc4cccnc4)ccc32)cc1 CHEMBL427284 IC50 7.8 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(O)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL226881 IC50 7.8 nM
CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4ccccn4)ccc3N2C1 CHEMBL595814 IC50 7.81 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCc2nonc2C)c1=O CHEMBL433771 IC50 7.9 nM
CCOc1ccc(/C=C/C(=O)OC)cc1CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1c(F)cccc1Cl)C(C)C CHEMBL81038 IC50 7.95 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(OCCBr)cc1 CHEMBL216447 Ki 8.0 nM
O=C1C(=O)N(Cc2ccc(I)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133258 IC50 8.1 nM
O=C1Nc2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc2C1=O CHEMBL62993 Ki 8.3 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(OCCF)cc1 CHEMBL215480 IC50 8.3 nM
O=C1C(=O)N(Cc2ccc(F)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL198682 pIC50 8.318 nM
COc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CC[C@H]4COc4ccccc4)ccc32)cc1 CHEMBL200813 pIC50 8.318 nM
Cc1ccc(S(=O)(=O)OCCOc2ccc(CN3C(=O)C(=O)c4cc(S(=O)(=O)N5CCC[C@H]5COc5ccccc5)ccc43)cc2)cc1 CHEMBL386510 Ki 8.6 nM
O=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL1762346 IC50 8.6 nM
O=C1C(=O)N(Cc2ccc(F)cc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL200886 pIC50 8.71 nM
CCCCCCCCN(C)CNCC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1ccnc(NCc2nonc2C)c1=O CHEMBL178514 IC50 9.0 nM
COc1ccc(-c2nc(C)no2)cc1CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)C(C)C CHEMBL360880 IC50 9.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(OC)cc1 CHEMBL217777 Ki 9.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cnnn1Cc1ccccc1 CHEMBL1683316 IC50 9.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)Oc2ccccc2Cl)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4227628 IC50 9.0 nM
O=C1C(=O)N(Cc2cccc(F)n2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL372994 IC50 9.1 nM
CCCCCCN(C)CC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1cc(C(C)(C)C)nc(NCc2nonc2C)c1=O CHEMBL1160520 IC50 9.17 nM
C=Cc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COC)ccc32)cc1 CHEMBL513663 IC50 9.3 nM
O=C1C(=O)N(Cc2ccccc2F)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL200493 pIC50 9.333 nM
O=C1C(=O)N(Cc2ccccc2I)c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133256 IC50 9.6 nM
O=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL200785 IC50 9.7 nM
O=C1C(=O)N(Cc2ccc(Br)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL376112 pIC50 9.772 nM
CC(C)(C)[Si](C)(C)Oc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4ccccc4)ccc32)cc1 CHEMBL217821 Ki 9.8 nM
CC(C)C[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@H](C=O)CC(=O)O CHEMBL90307 IC50 10.0 nM
COc1ccc(C(C)=O)cc1CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)C(C)C CHEMBL167071 IC50 10.0 nM
C=CCOc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COC)ccc32)cc1 CHEMBL467252 IC50 10.0 nM
CC(C)C[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)O CHEMBL3940506 IC50 10.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccc2ccccc2n1)NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)C(=O)N[C@H](/C=C(\Cl)S(C)(=O)=O)CC(=O)O CHEMBL3673259 IC50 10.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccc2ccccc2n1)NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)C(=O)N[C@H](/C=C/S(C)(=O)=O)CC(=O)O CHEMBL3673263 IC50 10.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccc2ccccc2n1)NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)C(=O)N[C@H](/C=C/S(=O)(=O)Oc1ccccc1)CC(=O)O CHEMBL3673267 IC50 10.0 nM
CCCCCC(=O)N1CCC(C(=O)N[C@@H](CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)CC1 CHEMBL4226868 IC50 10.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)C2CC(F)(F)C2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4228438 IC50 10.0 nM
COC(=O)c1cncc(OC[C@@H]2CCCN2S(=O)(=O)c2ccc3c(c2)C(=O)C2=NCC(C)(C)CN23)c1 CHEMBL603437 IC50 10.14 nM
O=C1C(=O)N(Cc2ccc(F)nc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL200653 pIC50 10.23 nM
CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4cc(Cl)ccn4)ccc3N2C1 CHEMBL606369 IC50 10.24 nM
CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4ccc(F)cc4)ccc3N2C1 CHEMBL592987 IC50 10.77 nM
O=C1C(=O)N(Cc2ccc(F)nc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL370012 IC50 10.9 nM
O=C1C(=O)N(Cc2ccc(OCCOCCF)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL1762351 IC50 10.9 nM
CCCCCCN(C)CNCC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1ccnc(NCc2nonc2C)c1=O CHEMBL359598 IC50 11.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2C[C@H](O)CO CHEMBL511723 IC50 11.0 nM
O=C1C(=O)N(Cc2cn(CCF)nn2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL1762361 IC50 11.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)c2ccc(Cl)cc2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4228922 IC50 11.0 nM
CSc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CC[C@H]4COc4ccccc4)ccc32)cc1 CHEMBL382084 pIC50 11.22 nM
O=C1C(=O)N(Cc2cccc(I)c2)c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133257 IC50 11.6 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CC[C@H](F)CO CHEMBL2381343 IC50 11.8 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCc2cncs2)c1=O CHEMBL180273 IC50 12.0 nM
CC(C)[C@H](OC(=O)Nc1ccc(Oc2ccccc2)cc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL181341 IC50 12.0 nM
COc1ccc(-c2nc(C)no2)cc1[C@@H](O)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)C(C)C CHEMBL361111 IC50 12.0 nM
CC(=O)Oc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4ccccc4)ccc32)cc1 CHEMBL200476 IC50 12.0 nM
O=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccc(F)cc3F)cc21 CHEMBL1762364 IC50 12.0 nM
CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H]1CC(=O)OC1O)C(C)C)C(C)C CHEMBL1835210 IC50 12.0 nM
CC(C)C(=O)N1CCC(C(=O)N[C@@H](CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)CC1 CHEMBL4226499 IC50 12.0 nM
CC(C)(C)C(=O)N1CCC(C(=O)N[C@@H](CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)CC1 CHEMBL4224702 IC50 12.0 nM
O=C1C(=O)N(Cc2ccc(F)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL372607 pIC50 12.02 nM
O=C1C(=O)N(Cc2cn(CCF)nn2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL456798 IC50 12.2 nM
CSc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4ccccc4)ccc32)cc1 CHEMBL200220 pIC50 12.3 nM
O=C1C(=O)N(Cc2ccc(F)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccc(F)cc3F)cc21 CHEMBL516941 EC50 12.4 nM
Cc1cccnc1OC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C1=NCC(C)(C)CN12 CHEMBL592988 IC50 12.57 nM
O=C1C(=O)N(Cc2ccc(OCCBr)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL385930 Ki 12.6 nM
O=C1C(=O)N(Cc2ccc(F)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COCc3cn(CCF)nn3)cc21 CHEMBL518382 EC50 12.6 nM
O=C1C(=O)N(Cc2cccc([N+](=O)[O-])c2)c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133147 IC50 12.8 nM
CC(C)C[C@H](NC(=O)CNc1cccc2ccccc12)C(=O)N[C@H](C=O)CC(=O)O CHEMBL90224 IC50 13.0 nM
CC(C)CC(NC(=O)CNc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O CHEMBL322631 IC50 13.0 nM
CCCCCCN(C)CNCC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1cc(C(C)C)nc(NCc2nonc2C)c1=O CHEMBL180646 IC50 13.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CNCN1CCc2ccccc2C1)n1ccnc(NCc2nonc2C)c1=O CHEMBL360788 IC50 13.0 nM
CCCCCN(C)CNCC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1ccnc(NCc2nonc2C)c1=O CHEMBL181623 IC50 13.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1I)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3977587 Ki 13.0 nM
C[C@H](NC(=O)C(=O)NC1CCCCC1)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3917557 Ki 13.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CC(O)CCl CHEMBL515299 IC50 13.3 nM
O=C1C(=O)N(Cc2cn(CCF)nn2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccc(F)cc3F)cc21 CHEMBL1762366 IC50 13.4 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C1=NCC3(CCCCC3)CN12 CHEMBL604054 IC50 13.61 nM
O=C1C(=O)N(Cc2ccc(OCCOCCOCCF)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL1762352 IC50 13.7 nM
COc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4CF)ccc32)cc1 CHEMBL3133259 IC50 13.7 nM
COc1ccc(OC[C@@H]2CCCN2S(=O)(=O)c2ccc3c(c2)C(=O)C2=NCC(C)(C)CN23)cc1 CHEMBL595590 IC50 13.83 nM
O=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133252 IC50 13.9 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CCCc1ccccc1)n1cc(C(C)(C)C)nc(NCc2nonc2C)c1=O CHEMBL180623 IC50 14.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CN[C@@H](C)c1ccccc1)n1ccnc(NCc2nonc2C)c1=O CHEMBL181274 IC50 14.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CNCN1Cc2ccccc2C1)n1ccnc(NCc2nonc2C)c1=O CHEMBL367356 IC50 14.0 nM
CC(C)[C@H](OC(=O)Nc1ccc(F)c(F)c1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL178300 IC50 14.0 nM
CC(C)[C@H](OC(=O)Nc1ccc(Cl)cc1Cl)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL360037 IC50 14.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL91423 Ki 14.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)c2ccccc2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4228349 IC50 14.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)OC2CCCC2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4226345 IC50 14.0 nM
Cc1ccccc1OC(=O)N1CCC(C(=O)N[C@@H](CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)CC1 CHEMBL4228290 IC50 14.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)Oc2ccccc2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4227309 IC50 14.0 nM
CCOC(=O)N1CCN(C[C@@H]2CCCN2S(=O)(=O)c2ccc3c(c2)C(=O)C2=NCC(C)(C)CN23)CC1 CHEMBL593223 IC50 14.32 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cn(-c2ccc3c(c2)OCCO3)nn1 CHEMBL1683178 Ki 14.5 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C1=NCC3(CCCC3)CN12 CHEMBL595778 IC50 14.83 nM
CCCCN(C)CNCC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1ccnc(NCc2nonc2C)c1=O CHEMBL179551 IC50 15.0 nM
Cc1ccccc1N1C(=O)c2c(C)nc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C1=O CHEMBL183437 IC50 15.0 nM
CC(C)[C@H](NC(=O)OCc1cc(Cl)ccc1Cl)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL186358 IC50 15.0 nM
CC(=O)N1N=C(c2cc(F)ccc2F)C[C@H]1c1cccc(O)c1 CHEMBL195232 IC50 15.0 nM
CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H]1CC(=O)OC1O)C(C)C)C(C)C CHEMBL1835209 IC50 15.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1-c1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL371926 Ki 15.0 nM
O=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccc(F)cc3F)cc21 CHEMBL1762365 IC50 15.2 nM
O=C1C(=O)N(Cc2ccc(F)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133255 IC50 15.2 nM
CCCCCCN(C)CNCC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1cc(C(C)(CC)CC)nc(NCc2nonc2C)c1=O CHEMBL362074 IC50 16.0 nM
COc1ccc(I)cc1[C@@H](O)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)C(C)C CHEMBL183619 IC50 16.0 nM
COC(=O)CN1C(=O)c2c(C)nc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C1=O CHEMBL183151 IC50 16.0 nM
Cc1nc2ccc(C#N)cc2c2c1C(=O)N(c1c(C)nn(C)c1C)C2=O CHEMBL359879 IC50 16.0 nM
COc1ccc(C(C)=O)cc1[C@@H](O)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)C(C)C CHEMBL360046 IC50 16.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)Oc2ccccc2F)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4228280 IC50 16.0 nM
O=C1C(=O)N(Cc2ccc(F)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cc(F)cc(F)c3)cc21 CHEMBL456592 EC50 16.8 nM
CCCN(C)CNCC(=O)[C@H](CC(=O)O)NC(=O)C(CC)n1ccnc(NCc2nonc2C)c1=O CHEMBL181763 IC50 17.0 nM
CC(C)[C@H](OC(=O)Nc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL180263 IC50 17.0 nM
C#CC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)C(C)C)c1cc(Br)ccc1OC CHEMBL183109 IC50 17.0 nM
O=C1C(=O)N(Cc2ccc(F)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccc(F)c3)cc21 CHEMBL461249 EC50 17.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2C[C@H]1CO1 CHEMBL513297 IC50 17.0 nM
CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COC)cc(I)c21 CHEMBL3359186 IC50 17.4 nM
COc1ccc(Br)cc1CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)C(C)C CHEMBL82932 IC50 17.7 nM
CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@H]1CCC[C@H]2SC[C@@H](C(=O)N[C@H]3CC(=O)OC3O)N2C1=O CHEMBL329917 IC50 18.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCCn2cncn2)c1=O CHEMBL181948 IC50 18.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cn(-c2ccc(C(F)(F)F)cc2)nn1 CHEMBL1683176 IC50 18.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)c2cc3ccccc3s2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4227888 IC50 18.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)C2CCC(F)(F)CC2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4227988 IC50 18.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL1762358 IC50 18.3 nM
O=C1Nc2ccc(S(=O)(=O)N3CCC[C@H]3CNc3ccccc3)cc2C1=O CHEMBL1907830 Ki app 19.0 nM
CC(C)[C@H](OC(=O)Nc1ccc(F)cc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL181717 IC50 19.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2C[C@H](O)CF CHEMBL524017 IC50 19.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COP(C)(=O)c1ccccc1 CHEMBL88795 Ki 19.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)c2noc3ccccc23)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4228603 IC50 19.0 nM
O=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3CF)cc21 CHEMBL3133251 IC50 19.2 nM
O=C[C@@H](NC(=O)c1cnc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)nc1)C(=O)O CHEMBL117075 Ki 20.0 nM
O=C[C@H](CC(=O)O)NC(=O)c1cnc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)nc1 CHEMBL144423 Ki 20.0 nM
O=C(O)C[C@H](NC(=O)c1ccc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)s1)C(=O)CSCc1ccccc1Cl CHEMBL146453 Ki 20.0 nM
O=C(O)C[C@H](NC(=O)c1cnc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)nc1)C(=O)CSCc1ccccc1Cl CHEMBL149307 Ki 20.0 nM
O=C(O)C[C@H](NC(=O)c1ccc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)s1)C(=O)CSCc1cccnc1 CHEMBL357676 Ki 20.0 nM
CC(C)[C@H](OC(=O)NCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL178602 IC50 20.0 nM
CC(C)[C@H](OC(=O)Nc1ccccc1)C(=O)NC(CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL181976 IC50 20.0 nM
CC(C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)C(=O)N[C@H](/C=C/S(C)(=O)=O)CC(=O)O CHEMBL3673265 IC50 20.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)c2ccc(Cl)s2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4227032 IC50 20.0 nM
COc1ccccc1OC(=O)N1CCC(C(=O)N[C@@H](CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)CC1 CHEMBL4227101 IC50 20.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)c2ccon2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4224986 IC50 20.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4226512 IC50 20.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(Br)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL436989 IC50 20.1 nM
COC[C@@H]1CCCN1S(=O)(=O)c1cc(I)c2c(c1)C(=O)C(=O)N2CCCF CHEMBL3359187 IC50 20.1 nM
O=C1Nc2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccncc3)cc2C1=O CHEMBL197237 IC50 20.4 nM
CC(C)CC(NC(=O)[C@@H](CCC(=O)O)Oc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O CHEMBL100643 IC50 21.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CNCN1CCCCC1)n1cc(C(C)(C)C)nc(NCc2nonc2C)c1=O CHEMBL434147 IC50 21.0 nM
COCCNS(=O)(=O)c1ccc2nc(C)c3c(c2c1)C(=O)N(c1c(C)nn(C)c1C)C3=O CHEMBL362837 IC50 21.0 nM
CC(C)[C@H](NC(=O)OCc1ccc(Cl)c(Cl)c1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL186694 IC50 21.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cn(-c2ccccc2)nn1 CHEMBL1683173 IC50 21.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cn(-c2ccc([N+](=O)[O-])cc2)nn1 CHEMBL1683175 IC50 21.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1Cl)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL382967 Ki 21.0 nM
CC(C)(C)c1ccccc1NC(=O)C(=O)N1CCC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)C1 CHEMBL4228595 IC50 21.0 nM
O=C1C(=O)N(Cc2ccnc(F)c2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL373012 IC50 21.3 nM
C[C@H](NC(=O)C(=O)NCc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3926784 Ki 22.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)c2ccccc2Cl)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4227507 IC50 22.0 nM
O=C(Nc1ccc(-c2ccccn2)cc1)n1sc2ccccc2c1=O CHEMBL3233635 IC50 22.1 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL1762354 IC50 22.4 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CNCN1C2CCC1CC2)n1ccnc(NCc2nonc2C)c1=O CHEMBL178674 IC50 23.0 nM
COC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)c1ccc2nc(C)c3c(c2c1)C(=O)N(c1c(C)nn(C)c1C)C3=O CHEMBL362007 IC50 23.0 nM
CC(=O)OCCN1C(=O)c2c(C)nc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C1=O CHEMBL192330 IC50 23.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCCCCCCCCC1CO1 CHEMBL521984 IC50 23.0 nM
Cc1cc(OC[C@@H]2CCCN2S(=O)(=O)c2ccc3c(c2)C(=O)C2=NCC(C)(C)CN23)ccc1F CHEMBL593481 IC50 23.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cn(-c2ccc(-c3ccccc3)cc2)nn1 CHEMBL1683174 IC50 23.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)c2cccc(Cl)c2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4227831 IC50 23.0 nM
CN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)ccc21 CHEMBL371879 IC50 23.3 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCOCCF)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL1762359 IC50 23.3 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CC[C@H](O)CF CHEMBL2381345 IC50 23.3 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(O)cc1 CHEMBL217220 Ki 23.5 nM
CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N1CCCC[C@H]1C(=O)N[C@H]1CC(=O)OC1O)C(C)C)C(C)C CHEMBL1835322 IC50 24.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL262735 Ki 24.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)Oc2ccccc2C(F)(F)F)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4225592 IC50 24.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCOCCF)cc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL1762355 IC50 24.4 nM
O=C1C2=NCC3(CCCCC3)CN2c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL595802 IC50 24.63 nM
CC(C)[C@H](NC(=O)OCc1ccc(Cl)cc1Cl)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL185356 IC50 25.0 nM
O=C(CCC(=O)N1CCCCC1)Nc1ccc2c(c1)C(=O)C(=O)NC2=O CHEMBL438969 IC50 25.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCC(C)F CHEMBL494141 IC50 25.0 nM
C=CCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COC)ccc21 CHEMBL512101 IC50 25.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL91281 Ki 25.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)C(=O)Nc2ccccc2C(F)(F)F)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4226305 IC50 25.0 nM
CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)C=O)C(C)C CHEMBL4782926 Ki 25.0 nM
CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COCC)ccc21 CHEMBL2348698 IC50 25.6 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CC[C@@H](O)CF CHEMBL2381348 IC50 25.9 nM
CC[C@H](C)[C@@H](C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)c1nnc(-c2ccccc2)o1)C3)N(C)C(C)=O CHEMBL71654 Ki 26.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CNCN(C)CC)n1ccnc(NCc2nonc2C)c1=O CHEMBL264344 IC50 26.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCc2nccs2)c1=O CHEMBL181768 IC50 26.0 nM
Cc1cc(OCC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)C(=O)Nc2cccc3ccccc23)C(C)C)cc(=O)o1 CHEMBL3951248 Ki 26.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)Oc2ccc(Cl)cc2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4228543 IC50 26.0 nM
O=C1C(=O)N(Cc2ccc(F)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccc(F)cc3)cc21 CHEMBL516490 EC50 26.1 nM
CCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COC)cc(Br)c21 CHEMBL3359193 IC50 26.2 nM
O=C1C(=O)N(Cc2ccc(OCCOCCOCCF)cc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL1762348 IC50 26.9 nM
CC(=O)OCCN1C(=O)c2c(-c3ccccc3)nc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C1=O CHEMBL193674 IC50 27.0 nM
N#Cc1ccccc1NC(=O)C(=O)N1CCC(C(=O)N[C@@H](CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)CC1 CHEMBL4225476 IC50 27.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)C(=O)Nc2ccccc2F)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4226326 IC50 27.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL226779 IC50 27.8 nM
O=C1C(=O)N(Cc2ccc(OCCOCCF)cc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL1762347 IC50 27.9 nM
CC(C)[C@H](NC(=O)OCc1ccc(F)cc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL433784 IC50 28.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CCCc1ccccc1)n1cc(C(C)(C)C)nc(Nc2ccc3c(c2)OCCO3)c1=O CHEMBL248309 IC50 28.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1F)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL440211 Ki 28.0 nM
COc1ccc(OC)c([C@@H](O)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc2ccccc2)C(C)C)c1 CHEMBL360690 IC50 29.0 nM
CC(C)[C@H](NC(=O)OCc1cccc(F)c1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL425890 IC50 29.0 nM
CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COC)ccc21 CHEMBL521840 IC50 29.0 nM
CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](COC(C)(C)C)C(=O)N[C@H]1CC(=O)OC1O)C(C)C)C(C)C CHEMBL1835208 IC50 29.0 nM
C[C@H](NC(=O)C(=O)NCc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3928643 Ki 29.0 nM
O=C1C(=O)N(Cc2ccnc(F)c2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL196855 IC50 29.2 nM
O=C(O)C[C@H](NC(=O)c1ccc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)nc1)C(=O)CSc1ccccc1Cl CHEMBL147775 Ki 30.0 nM
O=C(O)C[C@H](NC(=O)c1cnc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)s1)C(=O)CSCc1ccccc1Cl CHEMBL435284 Ki 30.0 nM
O=C(O)C[C@H](NC(=O)c1ccc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)s1)C(=O)CSCc1ccncc1 CHEMBL357214 Ki 30.0 nM
CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL23226 IC50 30.0 nM
CC(C)[C@H](NC(=O)Oc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL180927 IC50 30.0 nM
CC(C)[C@H](NC(=O)OCC1CCCC1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL363509 IC50 30.0 nM
CC(C)[C@H](NC(=O)OCc1ccc(F)c(F)c1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL186499 IC50 30.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCCCO CHEMBL522148 IC50 30.0 nM
CC(=O)c1ccc(OC[C@@H]2CCCN2S(=O)(=O)c2ccc3c(c2)C(=O)C2=NCC(C)(C)CN23)cc1 CHEMBL603436 IC50 30.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cn(Cc2ccccc2)nn1 CHEMBL1683179 IC50 30.0 nM
CCOC(=O)/C=C/[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)c1ccccc1)C(C)C CHEMBL2324341 IC50 30.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccccn1)NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)C(=O)N[C@H](/C=C/S(=O)(=O)c1ccccc1)CC(=O)O CHEMBL3678068 IC50 30.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)C(=O)N[C@H](/C=C/S(C)(=O)=O)CC(=O)O CHEMBL3678066 IC50 30.0 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)C1Cc2ccccc2C1)C(=O)N[C@H](/C=C/S(C)(=O)=O)CC(=O)O CHEMBL3673264 IC50 30.0 nM
CC(C)(C)c1ccccc1OC(=O)N1CCC(C(=O)N[C@@H](CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)CC1 CHEMBL4226811 IC50 30.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)C2CCCCC2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4227607 IC50 30.0 nM
O=C1Nc2ccc(S(=O)(=O)N3CCCC3CNc3ccccc3)cc2C1=O CHEMBL59721 pIC50 30.97 nM
C=CCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COC)ccc21 CHEMBL468088 IC50 31.0 nM
O=C(NCCc1ccccc1)n1sc2ccccc2c1=O CHEMBL2391912 IC50 31.0 nM
O=C(NCCc1cccs1)n1sc2ccccc2c1=O CHEMBL3233626 IC50 31.05 nM
COC[C@@H]1CCCN1S(=O)(=O)c1cc(Br)c2c(c1)C(=O)C(=O)N2CCCCF CHEMBL3359196 IC50 31.5 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(O)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL427283 IC50 31.8 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL3934331 Ki 32.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CNCN1CCCC1)n1ccnc(NCc2nonc2C)c1=O CHEMBL424789 IC50 33.0 nM
Cc1nc2ccc(S(N)(=O)=O)cc2c2c1C(=O)N(c1c(C)nn(C)c1C)C2=O CHEMBL359726 IC50 33.0 nM
CC(C)[C@H](NC(=O)CCC(=O)OCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL186691 IC50 33.0 nM
CC(=O)OCCN1C(=O)c2c(/C=C/c3ccc(C(F)(F)F)cc3)nc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C1=O CHEMBL191738 IC50 33.0 nM
CC(=O)OCCN1C(=O)c2c(-c3ccc(F)c(Cl)c3)nc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C1=O CHEMBL426991 IC50 33.0 nM
CC(=O)OCCN1C(=O)c2c(-c3cccnc3)nc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C1=O CHEMBL191944 IC50 33.0 nM
CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1C(=O)NC(C(=O)O)C(=O)CF CHEMBL237310 IC50 33.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1cc(I)c2c(c1)C(=O)C(=O)N2CCCCO CHEMBL3359189 IC50 33.2 nM
CC(C)[C@H](NC(=O)OCc1ccc(Cl)cc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL185677 IC50 34.0 nM
COc1cccc(CCC(=O)n2sc3ccccc3c2=O)c1 CHEMBL3360047 IC50 34.9 nM
CC(C)COC(=O)N[C@H](C(=O)NC(CC(=O)O)C(=O)CF)C(C)C CHEMBL365013 IC50 35.0 nM
CC(C)[C@H](NC(=O)OCc1ccc(F)cc1F)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL185711 IC50 35.0 nM
C/C=C/OC(=O)Oc1ccc(OCC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)C(=O)Nc2cccc3ccccc23)C(C)C)cc1 CHEMBL3976524 Ki 35.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1Cl)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL194207 Ki 35.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)Oc2cccc(Cl)c2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4225235 IC50 35.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCc2cccs2)c1=O CHEMBL361613 IC50 36.0 nM
CC(C)[C@H](NC(=O)OCc1ccccc1Cl)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL183161 IC50 36.0 nM
CC(C)[C@H](NC(=O)OCc1cccc(Cl)c1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL187104 IC50 36.0 nM
CC(=O)OCCN1C(=O)c2c(-c3ccco3)nc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C1=O CHEMBL370952 IC50 36.0 nM
COC(=O)CCN1C(=O)c2c(C)nc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C1=O CHEMBL180901 IC50 37.0 nM
COC(=O)N[C@H](C(=O)NC(CC(=O)O)C(=O)CF)C(C)C CHEMBL187294 IC50 37.0 nM
CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4ccc(Cl)cc4)ccc3N2C1 CHEMBL607194 IC50 37.0 nM
CC(C)[C@H](NC(=O)OCc1ccccc1F)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL186277 IC50 38.0 nM
C[C@H](NC(=O)C(=O)NC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3927125 Ki 38.0 nM
Cc1ccc(NC(=O)n2sc3ccccc3c2=O)nc1 CHEMBL3233622 IC50 38.15 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)cc(F)cc1F CHEMBL430839 Ki 39.0 nM
O=C[C@H](CC(=O)O)NC(=O)C(CCCCNS(=O)(=O)c1ccc(O)c(C(=O)O)c1)c1ccccc1 CHEMBL331403 Ki app 40.0 nM
Cc1cc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)sc1C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1Cl CHEMBL148162 Ki 40.0 nM
CC(=O)OCCN1C(=O)c2c(C(C)C)nc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C1=O CHEMBL363427 IC50 40.0 nM
CC(=O)OC(C(=O)Nc1cccc2c1C(=O)C(=O)NC2=O)c1ccccc1 CHEMBL439872 IC50 40.0 nM
COc1ccc(CNC(=O)n2sc3ccccc3c2=O)cc1 CHEMBL2391780 IC50 40.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1ccc2ccccc2n1)NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)C(=O)N[C@H](/C=C/S(=O)(=O)c1ccccc1)CC(=O)O CHEMBL3673266 IC50 40.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)C(=O)N[C@H](/C=C/S(C)(=O)=O)CC(=O)O CHEMBL3678069 IC50 40.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)C(=O)Nc2ccccc2)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4228374 IC50 40.0 nM
CC(C)[C@H](NC(=O)[C@H](O)c1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1 CHEMBL183760 IC50 41.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCCCF CHEMBL494140 IC50 41.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1cc(F)c2c(c1)C(=O)C(=O)N2CCCF CHEMBL3359203 IC50 41.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)cccc1F CHEMBL90914 Ki 41.0 nM
O=C(NCc1ccccn1)n1sc2ccccc2c1=O CHEMBL3233623 IC50 41.53 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2 CHEMBL60190 Ki 41.8 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CNCN(C)C)n1ccnc(NCc2nonc2C)c1=O CHEMBL181027 IC50 42.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(OCC2CO2)cc1 CHEMBL494220 IC50 42.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1ccc(O)cc1 CHEMBL3906503 Ki 42.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1-c1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL196266 Ki 42.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 CHEMBL493127 IC50 43.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(C(F)CBr)cc1 CHEMBL467251 IC50 43.0 nM
C[C@H](NC(=O)C(=O)NCc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3961549 Ki 43.0 nM
C[C@H](NC(=O)C(=O)Nc1cccc2c1CCCC2)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3944828 Ki 43.0 nM
CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4CN4CCNCC4)ccc3N2C1 CHEMBL592994 IC50 43.63 nM
O=C1Nc2ccc(S(=O)(=O)N3CCCC3CSc3ccccc3)cc2C1=O CHEMBL63493 pIC50 43.95 nM
Cc1nc2ccc(S(=O)(=O)N3CCOCC3)cc2c2c1C(=O)N(C)C2=O CHEMBL183340 IC50 44.0 nM
C=CCNC(=O)CCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O CHEMBL203900 IC50 44.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cn(-c2ccc(OC)cc2)nn1 CHEMBL1683177 IC50 44.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)c2cccc3ccccc23)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4226046 IC50 44.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCc2ccon2)c1=O CHEMBL362191 IC50 46.0 nM
CC(C)[C@H](NC(=O)OCCCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL363223 IC50 46.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL88540 Ki 46.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1cccc2ccccc12 CHEMBL90268 Ki 46.0 nM
CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COCC(F)(F)F)ccc21 CHEMBL2348860 IC50 46.8 nM
CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COC)cc(Br)c21 CHEMBL3359194 IC50 46.9 nM
O=C(CCc1ccccc1Cl)n1sc2ccccc2c1=O CHEMBL3360052 IC50 47.3 nM
COc1ccc(OC)c(CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc2ccccc2)C(C)C)c1 CHEMBL166513 IC50 48.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCc2nc(C)no2)c1=O CHEMBL360956 IC50 48.0 nM
O=C(NCCCc1ccccc1)n1sc2ccccc2c1=O CHEMBL3233627 IC50 49.04 nM
O=C(NCCc1ccccn1)n1sc2ccccc2c1=O CHEMBL3233624 IC50 49.39 nM
COc1ccc(CCC(=O)n2sc3ccccc3c2=O)cc1 CHEMBL3360048 IC50 49.7 nM
O=C[C@H](CC(=O)O)NC(=O)c1ccc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)nc1 CHEMBL358725 Ki 50.0 nM
O=C(O)CC(NC(=O)[C@@H](OC(=O)Nc1ccccc1)C1CCCCC1)C(=O)CF CHEMBL361757 IC50 50.0 nM
CC(C)[C@H](NC(=O)CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL187084 IC50 50.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CCCc1ccccc1)n1cc(C(C)(C)C)nc(NCCc2cccs2)c1=O CHEMBL392245 IC50 50.0 nM
C[C@H](NC(=O)C(=O)NC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3968852 Ki 50.0 nM
C#CCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COc3ccc(F)cc3F)ccc21 CHEMBL515661 EC50 50.1 nM
COC[C@@H]1CCCN1S(=O)(=O)c1cc(I)c2c(c1)C(=O)C(=O)N2CCCCF CHEMBL3359188 IC50 50.7 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCc2cc(C)no2)c1=O CHEMBL180763 IC50 51.0 nM
C[C@H](NC(=O)C(=O)Nc1ccc(F)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3983217 Ki 52.0 nM
C[C@H](NC(=O)C(=O)Nc1cc(C(F)(F)F)ccc1N1CCCC1)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3960740 Ki 52.0 nM
CCOc1ccc(OCC(=O)OC)cc1CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1c(F)cccc1Cl)C(C)C CHEMBL352554 IC50 53.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCCCc2nc(C)no2)c1=O CHEMBL361983 IC50 53.0 nM
O=C1NC(=O)c2cccc(NC(=O)c3cccc([N+](=O)[O-])c3)c2C1=O CHEMBL203971 IC50 53.0 nM
CC(C)C(NC(=O)COc1c(C(=O)O)ccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O CHEMBL101145 IC50 54.0 nM
O=C1NC(=O)c2ccc(NC(=O)c3ccc([N+](=O)[O-])cc3)cc2C1=O CHEMBL377940 IC50 54.0 nM
Cc1nc2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc2c2c1C(=O)N(c1c(C)nn(C)c1C)C2=O CHEMBL182541 IC50 55.0 nM
CCOc1cccc(NC(=O)CCC(=O)Nc2ccc3c(c2)C(=O)C(=O)NC3=O)c1 CHEMBL204529 IC50 55.0 nM
O=C(Nc1cccc(N2CCOCC2)c1)n1sc2ccccc2c1=O CHEMBL3233629 IC50 55.5 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CNCN1CCC(Cc2ccccc2)CC1)n1ccnc(NCc2nonc2C)c1=O CHEMBL441118 IC50 56.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCCCOS(=O)(=O)c1ccc(C)cc1 CHEMBL492518 IC50 56.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CC[C@@H](F)CO CHEMBL2381346 IC50 56.0 nM
O=C(NCc1ccc(N2CCOCC2)cc1)n1sc2ccccc2c1=O CHEMBL3233639 IC50 56.85 nM
O=C(CCc1ccc(Cl)cc1)n1sc2ccccc2c1=O CHEMBL3360053 IC50 56.9 nM
CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COC)cc(Cl)c21 CHEMBL3359199 IC50 57.7 nM
CC(=O)OCCN1C(=O)c2c(-c3ccc(C(=O)N(C)C)cc3)nc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C1=O CHEMBL364906 IC50 58.0 nM
C[C@H](NC(=O)C(=O)Nc1cc(C(C)(C)C)ccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL194235 Ki 58.0 nM
O=C1Nc2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc2C1=O CHEMBL197535 IC50 58.3 nM
CC(C)C[C@H](NC(=O)CCOc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O CHEMBL102901 IC50 59.0 nM
CCCNC(=O)CCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O CHEMBL382569 IC50 59.0 nM
CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4CNC4CCCCC4)ccc3N2C1 CHEMBL595576 IC50 59.0 nM
CO[C@H]1CCN(C(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(C)=O)C(C)C)C(C)C)[C@@H]1C(=O)N[C@H]1CC(=O)OC1O CHEMBL1835211 IC50 59.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(-c2ccccc2)oc2ccccc2c1=O CHEMBL3910815 Ki 59.0 nM
O=C(O)C[C@H](NC(=O)c1cc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)on1)C(=O)CSCc1ccccc1Cl CHEMBL146466 Ki 60.0 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)c1ccccc1)C(=O)N[C@H](/C=C(\Cl)S(C)(=O)=O)CC(=O)O CHEMBL3678074 IC50 60.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COc1ccccc1F CHEMBL3945053 Ki 60.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cnccn1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL1199647 Ki 60.0 nM
CC(C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)c1ccccc1)C(=O)N[C@H](/C=C/S(C)(=O)=O)CC(=O)O CHEMBL3673262 IC50 60.0 nM
CN1CCN(S(=O)(=O)c2ccc(NC(=O)n3sc4ccccc4c3=O)cc2)CC1 CHEMBL3233642 IC50 60.6 nM
CC(C)[C@H](NC(=O)Cc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL425543 IC50 61.0 nM
CCCOc1ccc(OCC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)C(=O)Nc2cccc3ccccc23)C(C)C)cc1 CHEMBL3922955 Ki 61.0 nM
C[C@H](NC(=O)C(=O)NCc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL3966591 Ki 61.0 nM
O=C1NC(=O)c2ccc(NC(=O)c3ccccc3[N+](=O)[O-])cc2C1=O CHEMBL204645 IC50 62.0 nM
CN1CCN(c2ccc(NC(=O)n3sc4ccccc4c3=O)cc2)CC1 CHEMBL3233633 IC50 62.01 nM
COc1ccc(OC)c(CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCC2CCCCC2)C(C)C)c1 CHEMBL353919 IC50 63.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)c1ncc(-c2ccccc2)o1)n1ccnc(NCc2nonc2C)c1=O CHEMBL179066 IC50 63.0 nM
C[C@H](NC(=O)C(=O)Nc1cc(C(C)(C)C)ccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL199253 Ki 63.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccccc1Br)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL327821 Ki 63.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(C)=O)n1cc(C(C)(C)C)nc(NCc2nonc2C)c1=O CHEMBL178339 IC50 64.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1ccnc(C(F)(F)F)n1 CHEMBL91305 Ki 64.0 nM
CC(C)(C)c1ccccc1NC(=O)C(=O)N1CCC(C(=O)N[C@@H](CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)CC1 CHEMBL4228733 IC50 64.0 nM
C[C@H](OC(=O)Nc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL182247 IC50 66.0 nM
COC(=O)c1cc(C(=O)Nc2ccc3c(c2)C(=O)C(=O)NC3=O)cc([N+](=O)[O-])c1 CHEMBL381094 IC50 66.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCCCCCCCCCC(F)F CHEMBL483408 IC50 66.0 nM
COC(=O)c1cc(OCC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)C(=O)Nc2cccc3ccccc23)C(C)C)no1 CHEMBL91236 Ki 67.0 nM
O=C(O)CCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O CHEMBL202971 IC50 68.0 nM
C[C@H](NC(=O)C(=O)Nc1cccc2c1CCCC2)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3909635 Ki 69.0 nM
CC(C)(C)OC(=O)C1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2 CHEMBL62282 pIC50 69.98 nM
O=C[C@H](CC(=O)O)NC(=O)C(CCCCNS(=O)(=O)c1ccc(O)c(C(=O)O)c1)c1cccs1 CHEMBL121581 Ki app 70.0 nM
O=C[C@H](CC(=O)O)NC(=O)C(CCCCNS(=O)(=O)c1ccc(O)c(C(=O)O)c1)c1cccc(Cl)c1 CHEMBL123412 Ki app 70.0 nM
O=C[C@H](CC(=O)O)NC(=O)c1cnc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)s1 CHEMBL146130 Ki 70.0 nM
CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL1794026 IC50 70.0 nM
C[C@H](OC(=O)NCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL178601 IC50 70.0 nM
CC(C)[C@H](OC(=O)Nc1ccccc1)C(=O)NC(CC(=O)O)C(=O)COc1cc(C(F)(F)F)nn1-c1ccccc1 CHEMBL178819 IC50 70.0 nM
O=C(CCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O)NCc1ccccc1 CHEMBL380344 IC50 70.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cnnn1-c1ccc(OC)cc1 CHEMBL1683185 IC50 70.0 nM
CC[C@H](C)[C@@H](C(=O)N[C@H]1CCc2cccc3c2N(C1=O)[C@H](C(=O)N[C@H](C=O)C(=O)O)C3)N(C)C(C)=O CHEMBL304368 Ki 71.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCCCOC)c1=O CHEMBL359643 IC50 71.0 nM
CCCOc1cccc(NC(=O)CCC(=O)Nc2ccc3c(c2)C(=O)C(=O)NC3=O)c1 CHEMBL206844 IC50 71.0 nM
C[C@H](NC(=O)C(=O)Nc1cc(C(C)(C)C)ccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL372185 Ki 71.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCc2noc(C)n2)c1=O CHEMBL178280 IC50 72.0 nM
COc1ccc(OC)c(CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc2c(F)cccc2Cl)C(C)C)c1 CHEMBL167670 IC50 73.0 nM
CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@H]1CC(=O)OC1O)C(C)C CHEMBL2370213 IC50 74.0 nM
C=CCCCCCCCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3COC)ccc21 CHEMBL513513 IC50 74.0 nM
COc1cccc(CNC(=O)n2sc3ccccc3c2=O)c1 CHEMBL2391779 IC50 74.0 nM
O=C1C(=O)N(CCCCF)c2ccc(S(=O)(=O)N3CCC[C@H]3COCCF)cc21 CHEMBL2348702 IC50 74.3 nM
CC(C)(C)c1ccccc1NC(=O)C(=O)N1[C@@H]2CCC(C(=O)N[C@@H](CC(=O)O)C(=O)COc3c(F)c(F)cc(F)c3F)[C@H]1CC2 CHEMBL4226573 IC50 75.0 nM
O=C(Nc1ccccc1)n1sc2ccccc2c1=O CHEMBL1703497 IC50 76.0 nM
CCC(C(=O)N[C@H](C=O)CC(=O)O)n1ccnc(NCc2nonc2C)c1=O CHEMBL360355 IC50 78.0 nM
O=C1NC(=O)c2ccc(NC(=O)c3ccccc3Cl)cc2C1=O CHEMBL205204 IC50 78.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCCO CHEMBL522324 IC50 78.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL197674 Ki 78.0 nM
O=C(O)CCCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O CHEMBL436945 IC50 79.0 nM
O=C(O)C[C@H](NC(=O)C1CCN(C(=O)C(=O)Nc2ccccc2Cl)CC1)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL4227939 IC50 79.0 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCCc2nc(C)no2)c1=O CHEMBL360915 IC50 80.0 nM
C=CC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)C(C)C)c1cc(Br)ccc1OC CHEMBL361397 IC50 80.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(C(F)CO)cc1 CHEMBL492385 IC50 80.0 nM
CC(C)[C@H](NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)[C@H](CC(=O)O)NC(=O)OCc1ccccc1)C(=O)N[C@H](/C=C/S(C)(=O)=O)CC(=O)O CHEMBL3678073 IC50 80.0 nM
O=C(NCc1ccco1)n1sc2ccccc2c1=O CHEMBL3233625 IC50 80.55 nM
CCC(=O)N[C@H](C(=O)NC(CC(=O)O)C(=O)CF)C(C)C CHEMBL433786 IC50 81.0 nM
CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCC[C@H]4COc4ccc(C(C)(C)C)cc4)ccc3N2C1 CHEMBL603219 IC50 81.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1cc(Br)c2c(c1)C(=O)C(=O)N2CCCF CHEMBL3359195 IC50 81.4 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCCn2cccn2)c1=O CHEMBL447233 IC50 82.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(C(F)(F)F)cc1 CHEMBL521822 IC50 82.0 nM
COc1ccc(OC[C@@H]2CCCN2S(=O)(=O)c2ccc3c(c2)C(=O)C2=NCC(C)(C)CN23)c(Cl)c1 CHEMBL594172 IC50 82.0 nM
CC(C)[C@H](NC(=O)c1cc2cc(F)ccc2[nH]1)C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1 CHEMBL168816 IC50 83.0 nM
O=C(CCCl)Nc1ccc2c(c1)C(=O)C(=O)NC2=O CHEMBL382481 IC50 83.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCC(F)=C(F)F CHEMBL493123 IC50 83.0 nM
CC(C)[C@H](NC(=O)C(=O)NC1CCCc2ccccc21)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL330534 Ki 84.0 nM
CC(C)[C@H](NC(=O)C(C)(O)c1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1 CHEMBL183564 IC50 85.0 nM
CC(NC(=O)n1sc2ccccc2c1=O)c1ccccc1 CHEMBL2391777 IC50 85.0 nM
O=C(NCc1ccccc1)n1sc2ccccc2c1=O CHEMBL1721135 IC50 86.0 nM
O=C(CCc1cccc(F)c1)n1sc2ccccc2c1=O CHEMBL3360050 IC50 87.7 nM
CCC(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(Nc2ccc3sc(C)nc3c2)c1=O CHEMBL181775 IC50 88.0 nM
COc1ccccc1CNC(=O)n1sc2ccccc2c1=O CHEMBL2391778 IC50 88.0 nM
CN(Cc1ccc(O)c(C(=O)O)c1)Cc1ccc(C(=O)N[C@@H](CC(=O)O)C(=O)CSCc2ccccc2Cl)s1 CHEMBL357191 Ki 90.0 nM
O=C(O)C[C@H](NC(=O)c1cnc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)cn1)C(=O)CSCc1ccccc1Cl CHEMBL423025 Ki 90.0 nM
CC(C)[C@H](NC(=O)COc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1ccc2ccccc2c1 CHEMBL116661 Ki 90.0 nM
Cc1nc2ccc(S(=O)(=O)O)cc2c2c1C(=O)N(c1c(C)nn(C)c1C)C2=O CHEMBL182105 IC50 90.0 nM
COC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCCCl CHEMBL493927 IC50 90.0 nM
CN1C(=O)C(=O)c2cc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)ccc21 CHEMBL371709 pIC50 91.2 nM
O=C(CCl)Nc1ccc2c(c1)C(=O)C(=O)NC2=O CHEMBL203788 IC50 92.0 nM
COCC[C@@H]1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCCCF CHEMBL2348693 IC50 92.3 nM
CCOc1ccc(OCC(=O)OC(C)C)cc1CC(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)CSCc1c(F)cccc1Cl)C(C)C CHEMBL168065 IC50 94.0 nM
C[C@H](NC(=O)C(=O)NCCc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3910303 Ki 94.0 nM
CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCC[C@H]3CCOC)ccc21 CHEMBL2348692 IC50 94.3 nM
CC(C)C[C@H](NC(=O)COc1ccccc1-c1ccccc1)C(=O)N[C@H]1CC(=O)OC1O CHEMBL99681 IC50 95.0 nM
Cc1cccc(CCC(=O)n2sc3ccccc3c2=O)c1 CHEMBL3360044 IC50 95.0 nM
COc1ccccc1C(=O)Nc1cccc2c1C(=O)C(=O)NC2=O CHEMBL206607 IC50 96.0 nM
C[C@H](NC(=O)C(=O)NC1CCCCC1)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3914770 Ki 96.0 nM
O=C(Nc1ccc(N2CCCCC2)cc1)n1sc2ccccc2c1=O CHEMBL3233634 IC50 97.92 nM
CC(C)[C@H](NC(=O)CCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL186486 IC50 98.0 nM
O=C1NC(=O)c2cccc(NC(=O)c3ccc(F)cc3)c2C1=O CHEMBL205169 IC50 99.0 nM