CC(C)CC(NC(=O)[C@H](CCC(=O)O)Oc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O CHEMBL101545 IC50 3.5 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1I)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3977587 Ki 6.0 nM
C[C@H](NC(=O)C(=O)NC1CCCCC1)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3917557 Ki 6.3 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1Cl)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL382967 Ki 7.0 nM
C[C@H](NC(=O)C(=O)Nc1cc(C(F)(F)F)ccc1N1CCCC1)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3960740 Ki 7.3 nM
C[C@H](NC(=O)C(=O)NC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3927125 Ki 7.4 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(C)=O)C(C)C)C(=O)N[C@H](C=O)CC(=O)O CHEMBL478081 IC50 8.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1c(F)cccc1F)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL315868 Ki 8.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL91423 Ki 9.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1-c1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL371926 Ki 9.0 nM
C[C@H](NC(=O)C(=O)Nc1ccc(F)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3983217 Ki 9.0 nM
CC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H]1CC(=O)OC1O)C(C)C CHEMBL430648 IC50 10.0 nM
CC(=O)N[C@@H](C(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H]1CC(=O)OC1O)C(C)C CHEMBL328412 IC50 10.0 nM
C[C@H](NC(=O)C(=O)Nc1cccc2c1CCCC2)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3944828 Ki 10.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COP(C)(=O)c1ccccc1 CHEMBL88795 Ki 11.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL91281 Ki 11.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL262735 Ki 11.0 nM
C[C@H](NC(=O)C(=O)NCc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3961549 Ki 11.0 nM
C[C@H](NC(=O)C(=O)NCc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3926784 Ki 11.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1Cl)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL194207 Ki 11.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccccc1C(F)(F)F)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL90185 Ki 12.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL197674 Ki 13.0 nM
CC(C)[C@H](NC(=O)C(=O)NC1CCCc2ccccc21)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL330534 Ki 13.0 nM
CC(C)CC(NC(=O)[C@@H](CCC(=O)O)Oc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O CHEMBL100643 IC50 15.0 nM
C[C@H](NC(=O)C(=O)Nc1cc(C(C)(C)C)ccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL199253 Ki 15.0 nM
C[C@H](NC(=O)C(=O)Nc1cc(C(C)(C)C)ccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL372185 Ki 15.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL88540 Ki 16.0 nM
C[C@H](NC(=O)C(=O)NCc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL3966591 Ki 16.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL3934331 Ki 17.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cnccn1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL1199647 Ki 17.0 nM
CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL23226 IC50 18.0 nM
O=c1cc2oc3cc(O)c(O)cc3c(-c3ccccc3[N+](=O)[O-])c-2cc1O CHEMBL1563898 AC50 18.0 nM
C[C@H](NC(=O)C(=O)Nc1cc(C(F)(F)F)ccc1N1CCOCC1)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3930460 Ki 19.0 nM
C[C@H](NC(=O)C(=O)Nc1cccc2c1CCCC2)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3909635 Ki 19.0 nM
C[C@H](NC(=O)C(=O)NCCc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3910303 Ki 19.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccccc1Br)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL327821 Ki 19.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1cccc2ccccc12 CHEMBL90268 Ki 20.0 nM
C[C@H](NC(=O)C(=O)NCc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3928643 Ki 20.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccccc1I)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL314096 Ki 20.0 nM
C[C@H](NC(=O)C(=O)NC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3968852 Ki 22.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1F)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL440211 Ki 22.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1c(F)c(F)nc(F)c1F)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL3950285 Ki 22.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1F)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3907290 Ki 23.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)cccc1F CHEMBL90914 Ki 25.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1-c1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL196266 Ki 25.0 nM
C[C@H](NC(=O)C(=O)NC1CCCCC1)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3914770 Ki 25.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccccc1Cl)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL92848 Ki 26.0 nM
CCCOc1ccc(OCC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)C(=O)Nc2cccc3ccccc23)C(C)C)cc1 CHEMBL3922955 Ki 33.0 nM
COc1cc(OC)c(-c2c3cc(O)c(=O)cc-3oc3cc(O)c(O)cc23)cc1OC CHEMBL1571034 AC50 36.7 nM
CC(C)C[C@H](NC(=O)CNc1cccc2ccccc12)C(=O)N[C@H](C=O)CC(=O)O CHEMBL90224 IC50 37.0 nM
CC(C)CC(NC(=O)CNc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O CHEMBL322631 IC50 37.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1ccc(O)cc1 CHEMBL3906503 Ki 37.0 nM
CC(C)[C@H](NC(=O)C(=O)NCc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL330110 Ki 40.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL93960 Ki 41.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)cc(F)cc1F CHEMBL430839 Ki 42.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1-c1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1ccccc1F CHEMBL3913186 Ki 42.0 nM
C/C=C/OC(=O)Oc1ccc(OCC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)C(=O)Nc2cccc3ccccc23)C(C)C)cc1 CHEMBL3976524 Ki 43.0 nM
C[C@H](NC(=O)C(=O)Nc1cc(C(C)(C)C)ccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL194235 Ki 49.0 nM
CC(C)[C@H](OC(=O)Nc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF CHEMBL180263 IC50 50.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccc(F)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL314733 Ki 59.0 nM
CCCCCCCc1ccc(NC(=O)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)C(C)C)cc1 CHEMBL316101 Ki 59.0 nM
CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1C(=O)NC(C(=O)O)C(=O)CF CHEMBL237310 IC50 61.0 nM
CCCc1nc2c(=O)n(C)c(=O)nc-2n(C)n1 CHEMBL1325945 AC50 63.6 nM
C[C@H](NC(=O)C(=O)NC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL3897550 Ki 68.0 nM
C[C@H](NC(=O)C(=O)NCc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL197242 Ki 70.0 nM
CC(C)[C@H](NC(=O)C(=O)NC1=CC2CCCC2C=C1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL3981787 Ki 70.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COc1ccccc1F CHEMBL3945053 Ki 71.0 nM
C[C@H](NC(=O)C(=O)Nc1cccc2c1CCCC2)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL3947447 Ki 72.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1I)C(=O)N[C@@H](CC(=O)O)C(=O)COP(=O)(c1ccccc1)c1ccccc1 CHEMBL3983710 Ki 78.0 nM
Oc1cc(F)ccc1CNc1ncccc1-c1nccnn1 CHEMBL5419962 Kd 80.0 nM
O=c1c(O)cccc2cc(O)c(O)c(O)c12 CHEMBL66953 AC50 80.4 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccccc1Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL328066 Ki 82.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccccc1-c1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL91442 Ki 85.0 nM
COc1ccccc1NC(=O)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F)C(C)C CHEMBL90589 Ki 88.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1ccnc(C(F)(F)F)n1 CHEMBL91305 Ki 95.0 nM
COC(=O)c1cc(OCC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)C(=O)Nc2cccc3ccccc23)C(C)C)no1 CHEMBL91236 Ki 96.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL327207 Ki 100.0 nM
O=C(O)C[C@H](NC(=O)c1ccc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)nc1)C(=O)CSc1ccccc1Cl CHEMBL147775 Ki 120.0 nM
O=C(CCC(=O)N1CCCCC1)Nc1ccc2c(c1)C(=O)C(=O)NC2=O CHEMBL438969 IC50 124.0 nM
CC(C)[C@H](NC(=O)C(=O)NCc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL315954 Ki 125.0 nM
COc1ccccc1NC(=O)CCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O CHEMBL203709 IC50 137.0 nM
C[C@H](NC(=O)C(=O)Nc1ccc(F)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)COC(=O)c1c(Cl)cccc1Cl CHEMBL3895160 Ki 142.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCSCC3)cc21 CHEMBL523131 IC50 151.0 nM
CC(C)[C@H](NC(=O)C(=O)NC12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL327683 Ki 152.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCC3)cc21 CHEMBL516251 IC50 156.0 nM
CC(C)[C@H](NC(=O)C(=O)NCCc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL316450 Ki 175.0 nM
Oc1cc(F)ccc1CNc1ncccc1-c1cnccn1 CHEMBL5440664 Kd 180.0 nM
COc1ccc(CN2C(=O)C(=C(C#N)C#N)c3cc(S(=O)(=O)N4CCSCC4)ccc32)cc1 CHEMBL490850 IC50 188.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccccn1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL1199648 Ki 188.0 nM
O=C(O)C[C@H](NC(=O)c1cnc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)nc1)C(=O)CSCc1ccccc1Cl CHEMBL149307 Ki 190.0 nM
O=c1ccc2c(-c3ccccc3S(=O)(=O)O)c3ccc(O)c(O)c3oc-2c1O CHEMBL210208 AC50 192.0 nM
COc1ccc(CN2C(=O)C(=C(C#N)C#N)c3cc(S(=O)(=O)N4CCC4)ccc32)cc1 CHEMBL476023 IC50 197.0 nM
COCCN(C(=O)COC(=O)c1cc2c(s1)CCC2)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O CHEMBL1414432 AC50 198.0 nM
O=C(O)CCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O CHEMBL202971 IC50 201.0 nM
CC(=O)OC(C(=O)Nc1cccc2c1C(=O)C(=O)NC2=O)c1ccccc1 CHEMBL439872 IC50 216.0 nM
Cn1nc(-c2ccccn2)nc2c(=O)n(C)c(=O)nc1-2 CHEMBL1463659 AC50 219.0 nM
Oc1cc(F)ccc1CNc1ncccc1-c1nc[nH]n1 CHEMBL5399818 Kd 220.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccccc1F)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL90516 Ki 221.0 nM
O=C1Nc2ccccc2/C1=N/N=C/c1ccc(O)c(O)c1 CHEMBL607979 AC50 226.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(Cl)c(Cl)c2)c2ccc(S(=O)(=O)N3CCSCC3)cc21 CHEMBL490851 IC50 230.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cc(C(C)(C)C)ccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL316102 Ki 232.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCCC3)cc21 CHEMBL477047 IC50 241.0 nM
Cc1cc(OCC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)C(=O)Nc2cccc3ccccc23)C(C)C)cc(=O)o1 CHEMBL3951248 Ki 254.0 nM
Oc1cc(F)ccc1CNc1ncccc1-c1ncccn1 CHEMBL3613794 Kd 270.0 nM
O=C(NN1C(=O)CSC1=S)C(=O)NN1C(=O)CSC1=S CHEMBL1594374 AC50 276.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(Cl)c(Cl)c2)c2ccc(S(=O)(=O)N3CCC3)cc21 CHEMBL510809 IC50 280.0 nM
O=C(CCCl)Nc1ccc2c(c1)C(=O)C(=O)NC2=O CHEMBL382481 IC50 283.0 nM
O=C(O)CC(CCc1ccccc1)OC1OC(CO)C(O)C(O)C1O CHEMBL1407474 AC50 283.0 nM
O=c1ccc2[n+]([O-])c3ccc([O-])cc3oc-2c1 CHEMBL1353221 AC50 285.0 nM
CC(C)C[C@H](NC(=O)CCOc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O CHEMBL102901 IC50 305.0 nM
CCN(CC)CCCC(C)n1c2nc(=O)[nH]c(=O)c-2nc2cc(Cl)ccc21 CHEMBL1709883 AC50 305.0 nM
CC(C)CC(NC(=O)CNc1cccc(Oc2ccccc2)c1)C(=O)N[C@H]1CC(=O)OC1O CHEMBL101182 IC50 308.0 nM
C[n+]1c(-c2ccccc2)cc2c(=Cc3ccc([N+](=O)[O-])cc3)c3ccccc3n21 CHEMBL1724452 AC50 309.0 nM
CC(C)C[C@H](NC(=O)C(C)Nc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O CHEMBL3142757 IC50 310.0 nM
Cn1cc(-c2cccnc2NCc2ccc(F)cc2O)nn1 CHEMBL5422136 Kd 310.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCCCC3)cc21 CHEMBL519148 IC50 325.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1cccc2ccccc12)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(-c2ccccc2)oc2ccccc2c1=O CHEMBL3910815 Ki 336.0 nM
O=C1C(Br)=C(N2CCN(CCOCCO)CC2)C(=O)c2c(O)ccc(O)c21 CHEMBL1700996 AC50 343.0 nM
NS(=O)(=O)c1ccc(N/N=C/c2ccc(O)c(O)c2O)c([N+](=O)[O-])c1 CHEMBL1972037 AC50 351.0 nM
COc1ccc(CN2C(=O)C(=C(C#N)C#N)c3cc(S(=O)(=O)N4CCCC4)ccc32)cc1 CHEMBL477659 IC50 358.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1C(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)c(Br)c(F)c1F CHEMBL3917051 Ki 381.0 nM
O=S(=O)(O)c1cc(O)c2cc(Nc3ccccc3)ccc2c1 CHEMBL1271266 AC50 403.0 nM
N#CC(C#N)=C1C(=O)Nc2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL376760 IC50 407.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCOCC3)cc21 CHEMBL492060 IC50 425.0 nM
O=C(c1cccc(-n2cccc2)c1)N1CCN(S(=O)(=O)c2ccccc2)CC1 CHEMBL1517216 AC50 433.0 nM
O=c1oc(-c2ccccc2)nc2sc3c(c12)CCC3 CHEMBL1500909 AC50 440.0 nM
COc1ccc(CN2C(=O)C(=C(C#N)C#N)c3cc(S(=O)(=O)N4CC[C@H]4COc4cccnc4)ccc32)cc1 CHEMBL1762357 IC50 450.0 nM
COc1ccc(CN2C(=O)C(=C(C#N)C#N)c3cc(S(=O)(=O)N4CCOCC4)ccc32)cc1 CHEMBL492061 IC50 453.0 nM
O=c1c(O)c(-c2cc(O)c(O)c(O)c2)oc2cc(O)cc(O)c12 CHEMBL164 AC50 461.0 nM
O=C(N/N=C/c1cn(Cc2cccc(F)c2)c2ccccc12)c1cc(O)cc(O)c1 CHEMBL1981446 AC50 461.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(Cl)c(Cl)c2)c2ccc(S(=O)(=O)N3CCCC3)cc21 CHEMBL478694 IC50 468.0 nM
Oc1cc(F)ccc1CNc1ncccc1-c1cccnn1 CHEMBL5395946 Kd 470.0 nM
O=C1NC(=O)c2ccccc2C1=O CHEMBL206435 IC50 474.0 nM
O=c1oc2c(cc1O)oc(=O)c1cc(O)c(O)c(O)c12 CHEMBL1601846 AC50 484.0 nM
CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O CHEMBL464982 AC50 505.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3cccnc3)cc21 CHEMBL1762356 IC50 509.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(Br)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL387556 IC50 515.0 nM
O=C[C@H](CC(=O)O)NC(=O)c1ccc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)s1 CHEMBL147642 Ki 540.0 nM
C[C@H](NC(=O)C(=O)Nc1ccccc1Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL197579 Ki 544.0 nM
COc1ccc(CN2C(=O)C(=C(C#N)C#N)c3cc(S(=O)(=O)N4CCCCC4)ccc32)cc1 CHEMBL521801 IC50 545.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(Cl)c(Cl)c2)c2ccc(S(=O)(=O)N3CCCCC3)cc21 CHEMBL492059 IC50 568.0 nM
CC(C)CC(NC(=O)CNCC(Cc1ccccc1)c1ccccc1)C(=O)N[C@H]1CC(=O)OC1O CHEMBL101622 IC50 589.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(Cl)c(Cl)c2)c2ccc(S(=O)(=O)N3CCOCC3)cc21 CHEMBL521972 IC50 591.7 nM
CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)CF CHEMBL205821 Ki 594.0 nM
CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(=O)N[C@H](/C=C/S(C)(=O)=O)CC(=O)O CHEMBL2324339 IC50 600.0 nM
COc1ccc(CN2C(=O)C(=C(C#N)C#N)c3cc(S(=O)(=O)N4CCC[C@H]4COc4cccnc4)ccc32)cc1 CHEMBL427284 IC50 610.0 nM
Cc1cnc(-c2cccnc2NCc2ccc(F)cc2O)nc1 CHEMBL5417769 Kd 620.0 nM
CC(C)[C@H](NC(=O)C(=O)Nc1ccncc1)C(=O)N[C@@H](CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F CHEMBL1199895 Ki 641.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(O)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL226881 IC50 650.0 nM
[O-][n+]1onc2c1CCc1c-2nn(-c2ccccc2Cl)[n+]1[O-] CHEMBL1602693 AC50 651.0 nM
O=C(O)C1CCCCC1C(=O)Nc1cccc(Br)c1 CHEMBL1435218 AC50 669.0 nM
COc1ccc(S(=O)(=O)N2CCN(C(=O)C3COc4ccccc4O3)CC2)cc1 CHEMBL1435948 AC50 685.0 nM
CN1C(=O)C(=C(C#N)C#N)c2cc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)ccc21 CHEMBL390932 IC50 698.0 nM
CC(C)C[C@H](NC(=O)COc1ccccc1-c1ccccc1)C(=O)N[C@H]1CC(=O)OC1O CHEMBL99681 IC50 717.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(O)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL427283 IC50 744.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CC[C@H]3COc3ccccc3)cc21 CHEMBL1762354 IC50 747.0 nM
O=C(N/N=C1\C/C(=N\NC(=O)c2ccncc2)c2ccccc21)c1ccncc1 CHEMBL3191689 AC50 749.0 nM
Cn1cnc(-c2cccnc2NCc2ccc(F)cc2O)c1 CHEMBL5431147 Kd 760.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL1762360 IC50 770.0 nM
O=C(O)c1ccc(-n2cccc2/C=N\NC(=O)c2cc3cc(Br)ccc3o2)cc1 CHEMBL2007178 AC50 801.0 nM
COc1cc(C)c2c(c1C=O)Oc1c(c(C)c(O)c3c1C(O)OC3=O)OC2=O CHEMBL173530 AC50 817.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3cccnc3)cc21 CHEMBL226828 IC50 823.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(Br)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL436989 IC50 840.0 nM
Oc1cc(F)ccc1CNc1ncccc1-c1ccncn1 CHEMBL5419392 Kd 850.0 nM
COc1ccc(/C=N/NC(=O)c2cc(O)c(O)c(O)c2)cc1Cn1cc([N+](=O)[O-])cn1 CHEMBL1985664 AC50 873.0 nM
O=C(Nc1ccc(S(=O)(=O)Nc2cnc3ccccc3n2)cc1)c1ccc(Cl)c([N+](=O)[O-])c1 CHEMBL1523328 AC50 905.0 nM
O=S(=O)(Nc1cc(Sc2nc[nH]n2)c(O)c2ccccc12)c1ccccc1 CHEMBL1335844 AC50 911.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL226779 IC50 918.0 nM
COc1cc2c(cc1OC)-c1c(OC)c(OC)cc3c1[C@H](C2)N(C)CC3 CHEMBL1497070 AC50 926.0 nM
N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CCC[C@H]3COc3ccccc3)cc21 CHEMBL1762358 IC50 927.0 nM
CC(C)C[C@H](NC(=O)COc1cccc2ccccc12)C(=O)N[C@H](C=O)CC(=O)O CHEMBL330535 IC50 940.0 nM
CC(C)C[C@H](NC(=O)COc1cccc2ccccc12)C(=O)N[C@H]1CC(=O)OC1O CHEMBL318386 IC50 940.0 nM
Oc1nc(Nc2ccc(F)cc2)cc2ccccc12 CHEMBL1522941 AC50 942.0 nM
O=C(COC(=O)c1ccccc1)Nc1ncc([N+](=O)[O-])s1 CHEMBL1473059 AC50 951.0 nM
Oc1cc(F)ccc1CNc1ncccc1-c1cn2ccccc2n1 CHEMBL5423749 Kd 970.0 nM
COc1ccc(S(=O)(=O)Nc2cc(Sc3nc[nH]n3)c(O)c3ccccc23)cc1 CHEMBL1540929 AC50 998.0 nM
O=C1C(=O)N(Cc2ccccc2)c2ccc([N+](=O)[O-])cc21 CHEMBL60306 Ki app 1000.0 nM
O=C[C@H](CC(=O)O)NC(=O)c1ccc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)cc1 CHEMBL422849 Ki 1000.0 nM