CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1cccc(Cl)c1C#N CHEMBL180672 IC50 0.003 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1ccccc1C#N CHEMBL382741 IC50 0.003 nM
CCOC(=O)CCc1ccc(OC[C@H](O)CNC(C)(C)Cc2ccc3ccccc3c2)c(C#N)c1 CHEMBL1204009 IC50 0.003 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1ccc(CCC(=O)O)cc1C#N CHEMBL570593 IC50 0.022 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=S)n2Cc1cccc(OCCO)c1 CHEMBL597397 IC50 0.4 nM
CCc1ccc(C(CC)(CC)NC(=O)c2c(C)nn3c2N[C@@H](c2ccccc2)CC3(C)C)cc1 CHEMBL1689060 IC50 0.94 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccc(OC)c(OCC)c1 CHEMBL597800 IC50 1.4 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccc(C)cc1 CHEMBL591240 IC50 1.6 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(C(F)(F)F)c(Cc3cccnc3SC)cc(OC)c21 CHEMBL1223714 IC50 1.6 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(C(C)C)cc1 CHEMBL1689051 IC50 1.7 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(OC)c(Cl)c1 CHEMBL1689057 IC50 1.7 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(C)c1 CHEMBL598436 IC50 1.8 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(C(F)(F)F)c(Cc3nccs3)cc(OC)c21 CHEMBL1223772 IC50 2.0 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(OC)cc1 CHEMBL1689052 IC50 2.0 nM
NS(=O)(=O)c1ccc(-c2nc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)sc2Cl)cc1 CHEMBL3093422 EC50 2.0 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(OCc2ccccc2)cc1 CHEMBL1689055 IC50 2.2 nM
CCC(CC)(NC(=O)c1cnn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(C)cc1 CHEMBL1688099 IC50 2.3 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccccc1 CHEMBL1689049 IC50 2.3 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(NC(=O)CN2CCN(C)CC2)c1 CHEMBL590539 IC50 2.4 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(C)cc1 CHEMBL1689047 IC50 2.4 nM
CC(C)c1ccc(-c2nc(=O)n(Cc3ccccc3)c3ccc(O)c(CC4CC4)c23)cc1 CHEMBL597208 IC50 2.5 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(C(F)(F)F)c(Cc3cccnc3[S+](C)[O-])cc(OC)c21 CHEMBL1223771 IC50 2.6 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(OC)c1 CHEMBL604506 IC50 2.7 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1cccc(Cl)c1C#N CHEMBL2112075 IC50 3.0 nM
CCOc1ccc(C(CC)(CC)NC(=O)c2c(C)nn3c2N[C@@H](c2ccccc2)CC3(C)C)cc1 CHEMBL1689053 IC50 3.0 nM
NS(=O)(=O)c1ccc(-c2nsc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)n2)cc1 CHEMBL3093424 EC50 3.0 nM
CS(=O)(=O)Nc1ccc(-c2nc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)sc2Cl)cc1 CHEMBL3093421 EC50 3.0 nM
N[C@@H](CNC(=O)Nc1cc(Cl)cc(S(=O)(=O)O)c1O)C(=O)O CHEMBL3980928 EC50 3.0 nM
Cc1c(Cl)cc(S(=O)(=O)O)cc1NC(=O)NCC(N)C(=O)O CHEMBL3972910 EC50 3.0 nM
COC(=O)[C@@H](N)CNC(=O)Nc1cc(Cl)cc(S(=O)(=O)O)c1O CHEMBL3937671 EC50 3.0 nM
C[C@@H](NC[C@H]1C[C@@H](c2ccc(F)c(C(=O)O)c2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5415372 EC50 3.1 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(OCC(=O)O)c1 CHEMBL597194 IC50 3.4 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccccc1 CHEMBL1689815 IC50 3.4 nM
CC(C)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(C(F)(F)F)cc1 CHEMBL1689809 IC50 3.5 nM
Cc1ccc([C@H]2C[C@@H](CN[C@H](C)c3cccc4ccccc34)Oc3ccccc32)cc1C(=O)O CHEMBL5428661 EC50 3.7 nM
C=CCc1c(O)ccc2c1c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccccc1 CHEMBL598638 IC50 3.9 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(C(F)(F)F)c(Cc3cccnc3OC)cc(OC)c21 CHEMBL1223712 IC50 4.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(Cc3cccnc3SC)cc(OC)c21 CHEMBL1223713 IC50 4.0 nM
C[C@@H](OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1-c1ccc(C(=O)O)cc1 CHEMBL1672970 IC50 4.0 nM
NS(=O)(=O)c1ccc(-c2nc(NC(=O)N(CCC(c3ccccc3F)c3ccccc3F)CCN3CCOCC3)sc2Cl)cc1 CHEMBL3093425 EC50 4.0 nM
Cc1c(Cl)cc(S(=O)(=O)O)cc1NC(=S)NC[C@H](N)C(=O)O CHEMBL3895461 EC50 4.0 nM
C[C@@H](NCCCc1cccc(C(F)(F)F)c1)c1cccc2ccccc12 CHEMBL1201284 EC50 4.0 nM
CCC(CC)(NC(=O)c1c(C)nn2c1NC(c1ccccc1)CC2(C)C)c1ccc(C)cc1 CHEMBL1689040 IC50 4.1 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccc(CC)cc1 CHEMBL597400 IC50 4.2 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccc(OC)cc1 CHEMBL597401 IC50 4.2 nM
CCc1ccc(C(CC)(CC)NC(=O)c2c(C)nn3c2N[C@@H](c2ccccc2)CC3(C)C)cc1 CHEMBL1689050 IC50 4.2 nM
Cc1c(C(=O)O)cccc1[C@@H]1C[C@H](CN[C@H](C)c2cccc3ccccc23)Oc2ccccc21 CHEMBL5430130 EC50 4.3 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccccc1 CHEMBL591475 IC50 4.4 nM
CCCC(CCC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(C(F)(F)F)cc1 CHEMBL1689811 IC50 4.4 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(OC)c(F)c1 CHEMBL1689058 IC50 4.6 nM
CCC(CC)(NC(=O)c1c(SC)nn2c1NC(c1ccccc1)CC2(C)C)c1ccc(C)cc1 CHEMBL1689046 IC50 4.7 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COc1ccc(CCC(=O)O)cc1 CHEMBL572163 IC50 4.8 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(C(C)=O)cc1 CHEMBL1689062 IC50 4.8 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(C)cc1 CHEMBL1688097 IC50 4.9 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(Cc3ccccc3)cc(OC)c21 CHEMBL1222427 IC50 5.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(Cc3ccccc3[S+](C)[O-])cc(OC)c21 CHEMBL1222492 IC50 5.0 nM
Cc1cc(-c2ccccc2[C@@H](C)OC[C@H](O)CNC(C)(C)Cc2ccc3ccccc3c2)ccc1C(=O)O CHEMBL1672972 IC50 5.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)NCCn3cnc(C(=O)O)c3C(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4086045 pEC50 5.012 nM
CCOC(=O)c1ccc(C(CC)(CC)NC(=O)c2cnn3c2NC(c2ccccc2)CC3(C)C)cc1 CHEMBL1688103 IC50 5.2 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(C)cc1 CHEMBL1687946 IC50 5.5 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(I)c(Br)cc(OC)c21 CHEMBL1223506 IC50 6.0 nM
CCCc1nn2c(c1C(=O)NC(CC)(CC)c1ccc(C)cc1)NC(c1ccccc1)CC2(C)C CHEMBL1689042 IC50 6.0 nM
CC(C)(CC1Cc2ccccc2C1)NC[C@@H](O)COc1cc(C2CC3CC2C2C(C(=O)O)C32)ccc1C#N CHEMBL1783764 IC50 6.0 nM
CS(=O)(=O)Nc1ccc(-c2nsc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)n2)cc1 CHEMBL3093423 EC50 6.0 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(Cl)c(OC)c1 CHEMBL1687956 IC50 6.1 nM
Cc1ccc([C@@H]2C[C@H](CN[C@H](C)c3cccc4ccccc34)Oc3ccccc32)cc1C(=O)O CHEMBL5423499 EC50 6.4 nM
CCCc1c(O)ccc2c1c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccccc1 CHEMBL598016 IC50 6.6 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(OC)cc1 CHEMBL1688087 IC50 6.6 nM
CCc1nn2c(c1C(=O)NC(CC)(CC)c1ccc(C)cc1)NC(c1ccccc1)CC2(C)C CHEMBL1689041 IC50 6.7 nM
Cc1ccc(N2CC(CN[C@H](C)c3cccc4ccccc34)Oc3ccccc32)cc1C(=O)O CHEMBL5395144 EC50 7.0 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(OCCO)c1 CHEMBL597396 IC50 7.3 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(F)cc1 CHEMBL1689818 IC50 7.3 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(Cl)cc1 CHEMBL1689816 IC50 7.4 nM
C[C@@H](NCC1CNc2ccccc2O1)c1cccc2ccccc12 CHEMBL5408750 EC50 7.4 nM
Cc1ccc([C@@H](C)OC[C@H](O)CNC(C)(C)Cc2ccc3ccccc3c2)c2c1O[C@@H]1[C@@H](C(=O)O)[C@H]21 CHEMBL3827259 IC50 7.45 nM
C[C@@H](NCC1CN(C)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5439351 EC50 7.5 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(C(F)(F)F)cc1 CHEMBL1689810 IC50 7.6 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)NCCNC(CO)(CO)CO)cc2)C1)c1cccc2ccccc12 CHEMBL4101097 pEC50 7.943 nM
C[C@@H](N[C@H]1CCN(c2ccc(S(=O)(=O)NCCn3cnc(C(=O)O)c3C(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4084641 pEC50 7.943 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(NC(=O)CN2CCN(CCCN(C)C)CC2)c1 CHEMBL590560 IC50 8.1 nM
Cc1cc(C(=O)O)cc([C@@H]2C[C@H](CN[C@H](C)c3cccc4ccccc34)Oc3ccccc32)c1 CHEMBL5401731 EC50 8.3 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(OCc2ccccc2)cc1 CHEMBL1688088 IC50 8.5 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C CHEMBL592176 IC50 9.0 nM
NS(=O)(=O)c1ccc(-c2nsc(NC(=O)N(CCC(c3ccc(F)cc3)c3ccc(F)cc3)CCN3CCOCC3)n2)cc1 CHEMBL3093429 EC50 9.0 nM
CS(=O)(=O)Nc1ccc(-c2nc(NC(=O)N(CCC(c3ccc(F)cc3)c3ccc(F)cc3)CCN3CCOCC3)sc2Cl)cc1 CHEMBL3093428 EC50 9.0 nM
Cc1ccc(C(=O)O)cc1[C@@H]1C[C@H](CN[C@H](C)c2cccc3ccccc23)Oc2ccccc21 CHEMBL5430868 EC50 9.3 nM
Cc1ccc([C@@H](C)OC[C@H](O)CNC(C)(C)Cc2ccc3sccc3c2)c2c1O[C@@H]1[C@@H](C(=O)O)[C@H]21 CHEMBL3827304 IC50 9.62 nM
Cc1ccc([C@](C)(O)c2nc3ccccc3s2)c(C)c1 CHEMBL1256368 pEC50 10.0 nM
CC1(C)C[C@@H](c2ccccc2)Nc2c(C(=O)NC34CC5CC(CC(C5)C3)C4)cnn21 CHEMBL1290328 IC50 10.0 nM
NS(=O)(=O)c1ccc(-c2nc(NC(=O)N(CCC(c3ccc(F)cc3)c3ccc(F)cc3)CCN3CCOCC3)sc2Cl)cc1 CHEMBL3093427 EC50 10.0 nM
COc1ccc(CC(C)(C)NC[C@H](O)COc2cccc3[nH]c(=O)[nH]c23)cc1 CHEMBL486278 IC50 11.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(C(F)(F)F)cc(OC)c21 CHEMBL1223507 IC50 11.0 nM
CC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1-c1ccc(C(=O)O)cc1 CHEMBL1672969 IC50 11.0 nM
CCCCc1nn2c(c1C(=O)NC(CC)(CC)c1ccc(C)cc1)NC(c1ccccc1)CC2(C)C CHEMBL1689043 IC50 11.0 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(OC)c(OC)c1 CHEMBL1689054 IC50 11.0 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(F)c(OC)c1 CHEMBL1689056 IC50 11.0 nM
Cc1cc(-c2ccccc2[C@@H](C)OC[C@H](O)CNC(C)(C)Cc2ccc(Cl)c(F)c2)ccc1C(=O)O CHEMBL1672973 IC50 12.0 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccccc1F CHEMBL1688086 IC50 12.0 nM
CCC(=O)Oc1ccc(C(CC)(CC)NC(=O)c2cnn3c2NC(c2ccccc2)CC3(C)C)cc1 CHEMBL1688092 IC50 12.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)NCCN)cc2)C1)c1cccc2ccccc12 CHEMBL4060025 pEC50 12.59 nM
C[C@@H](N[C@H]1CCN(c2ccc(S(=O)(=O)NCCN(C)C)cc2)C1)c1cccc2ccccc12 CHEMBL4067601 pEC50 12.59 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccc(OCC(=O)O)cc1 CHEMBL603248 IC50 12.6 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(CC)c1 CHEMBL598637 IC50 13.0 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(NC(=O)CN2CCN(CCOC)CC2)c1 CHEMBL590552 IC50 13.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(I)ccc(OC)c21 CHEMBL1223368 IC50 13.0 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(C(C)O)cc1 CHEMBL1689107 IC50 13.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(Br)cc(OC)c21 CHEMBL1223505 IC50 14.0 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(COC(C)=O)cc1 CHEMBL1688090 IC50 14.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(Cc3cccnc3)cc(OC)c21 CHEMBL1223711 IC50 15.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)NCCCCNC(CO)(CO)CO)cc2)C1)c1cccc2ccccc12 CHEMBL4100132 pEC50 15.85 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(C(F)(F)F)c(Br)cc(OC)c21 CHEMBL1223508 IC50 16.0 nM
CS(=O)(=O)Nc1ccc(-c2csc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)n2)cc1 CHEMBL3093411 EC50 16.0 nM
COc1ccc([C@@H](C)N[C@H](C)c2ccccc2)cc1-c1ccc(C(F)(F)F)cc1 CHEMBL1224424 EC50 17.0 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1cccc(Cl)c1 CHEMBL1689817 IC50 17.0 nM
CS(=O)(=O)c1sc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)nc1-c1ccccc1 CHEMBL3093419 EC50 17.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(-c3nn[nH]n3)cc2)C1)c1cccc2ccccc12 CHEMBL4126450 EC50 17.0 nM
Cc1ccc(CC(C)(C)NC[C@@H](O)CO[C@H](C)c2ccc(C)c3c2[C@@H]2[C@H](O3)[C@H]2C(=O)O)cc1C CHEMBL3827570 IC50 17.7 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)CO[C@@H](c1ccccc1CO)C1CC1 CHEMBL1672960 IC50 18.0 nM
CC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1cccc(-c2ccc(C(=O)O)cc2)c1 CHEMBL1672968 IC50 18.0 nM
Cc1ccc(CC(C)(C)NC[C@@H](O)CO[C@H](C)c2ccccc2C2CC3CC2C2C(C(=O)O)C32)cc1Cl CHEMBL1783935 IC50 18.0 nM
O=C(Nc1nc(-c2ccccc2)c(Cl)s1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL3093420 EC50 18.0 nM
N[C@@H](CNC(=O)Nc1cccc(S(=O)(=O)O)c1)C(=O)O CHEMBL3889990 EC50 18.0 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccc(OCC)cc1 CHEMBL596789 IC50 19.0 nM
NS(=O)(=O)c1ccc(-c2nc(NC(=O)N(CCC(c3cccc(F)c3)c3cccc(F)c3)CCN3CCOCC3)sc2Cl)cc1 CHEMBL3093426 EC50 19.0 nM
COc1ccc(CC(C)(C)NC[C@@H](O)CO[C@H](C)c2ccc(C)c3c2[C@@H]2[C@H](O3)[C@H]2C(=O)O)c(Cl)c1 CHEMBL3828187 IC50 19.6 nM
C[C@@H](NCCCc1cccc(C(F)(F)F)c1)c1cccc2ccccc12 CHEMBL1200776 pEC50 19.95 nM
C[C@@H](N[C@H]1CCN(c2ccc(S(N)(=O)=O)cc2)C1)c1cccc2ccccc12 CHEMBL4072950 pEC50 19.95 nM
O=C(Nc1nc2c(Cl)cccc2s1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377740 EC50 20.0 nM
O=C(Nc1nc2ccccc2s1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377735 EC50 20.0 nM
CS(=O)(=O)Nc1ccc(-c2nsc(NC(=O)N(CCC(c3ccc(F)cc3)c3ccc(F)cc3)CCN3CCOCC3)n2)cc1 CHEMBL3093430 EC50 20.0 nM
Cc1ccc([C@@H](C)OC[C@H](O)CNC(C)(C)CC2Cc3ccccc3C2)c2c1O[C@@H]1[C@@H](C(=O)O)[C@H]21 CHEMBL3827736 IC50 20.0 nM
C[C@@H](NCC1CN(C(=O)c2ccccc2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5417635 EC50 21.0 nM
Cc1ccc([C@@H](C)OC[C@H](O)CNC(C)(C)Cc2ccc3ccccc3c2)c2c1O[C@H]1[C@H](C(=O)O)[C@@H]21 CHEMBL3828483 IC50 21.6 nM
Cc1ccc([C@@H](C)OC[C@H](O)CNC(C)(C)Cc2ccc3c(c2)OCCO3)c2c1O[C@@H]1[C@@H](C(=O)O)[C@H]21 CHEMBL3827475 IC50 21.8 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)ccc(OC)c21 CHEMBL1223367 IC50 22.0 nM
COc1cc([C@@H](C)N[C@H](C)c2cccc(Cl)c2)nn1-c1ccc(Br)cc1 CHEMBL569182 EC50 23.0 nM
Cc1ccccc1[C@H](OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)C1CC1 CHEMBL1086282 IC50 23.0 nM
COc1cccc([C@@H](C)NCc2ccc(OC)c(-c3ccc(C(F)(F)F)cc3)c2)c1 CHEMBL1224340 EC50 23.0 nM
C[C@@H](OC[C@H](O)CNC(C)(C)Cc1ccc(Cl)c(F)c1)c1ccccc1-c1ccc(C(=O)O)cc1 CHEMBL1672971 IC50 23.0 nM
CCCCC(CCCC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(C(F)(F)F)cc1 CHEMBL1689812 IC50 23.0 nM
Cc1ccc(CC(C)(C)NC[C@@H](O)COc2cc(C3CC4CC3C3C(C(=O)O)C43)ccc2C#N)cc1F CHEMBL1783931 IC50 23.0 nM
O=C(Nc1nc(-c2ccccc2)ns1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL3093416 EC50 23.0 nM
C[C@@H](OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1CCC(=O)O CHEMBL1672966 IC50 24.0 nM
Cc1ccc(CC(C)(C)NC[C@@H](O)CO[C@H](C)c2ccccc2[C@@H]2C[C@@H]3C[C@H]2[C@H]2[C@H](C(=O)O)[C@@H]32)cc1F CHEMBL2368751 IC50 25.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(C#N)cc(OC)c21 CHEMBL1223509 IC50 25.0 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1cccc(F)c1 CHEMBL1688085 IC50 25.0 nM
Cc1ccc(CC(C)(C)NC[C@@H](O)CO[C@H](C)c2ccccc2C2CC3CC2C2C(C(=O)O)C32)cc1F CHEMBL1783933 IC50 25.0 nM
Cc1ccc(C(C)(O)c2nc3ccccc3s2)c(C)c1 CHEMBL1256367 pEC50 25.12 nM
C[C@@H](NCC1CN(CC(F)(F)F)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5432863 EC50 25.6 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(C(F)(F)F)c(Cc3ccccc3OC)cc(OC)c21 CHEMBL1222489 IC50 26.0 nM
C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccc(C(C)C)cc1 CHEMBL604713 IC50 27.0 nM
COc1ccc(CN[C@H](C)c2ccccc2)cc1-c1ccc(C(F)(F)F)cc1 CHEMBL1224341 EC50 27.0 nM
CSc1ccc(CC(C)(C)NC[C@@H](O)CO[C@H](C)c2ccc(C)c3c2[C@@H]2[C@H](O3)[C@H]2C(=O)O)cc1F CHEMBL3827041 IC50 27.6 nM
Cc1ccc([C@@H](C)OC[C@H](O)CNC(C)(C)CCCc2ccccc2)c2c1O[C@@H]1[C@@H](C(=O)O)[C@H]21 CHEMBL3827830 IC50 28.4 nM
C[C@@H](NCC1CN(c2ccc(F)c(C(=O)O)c2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5396296 EC50 29.6 nM
C#CCNc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C CHEMBL597811 IC50 30.0 nM
CC(C)C(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)(c1ccc(C(F)(F)F)cc1)C(C)C CHEMBL1689813 IC50 30.0 nM
Cc1ccc2nc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)sc2c1 CHEMBL2377749 EC50 30.0 nM
CS(=O)(=O)Nc1ccc2nc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)sc2c1 CHEMBL2377748 EC50 30.0 nM
CS(=O)(=O)Nc1ccc2sc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)nc2c1 CHEMBL2377743 EC50 30.0 nM
COc1cccc2sc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)nc12 CHEMBL2377741 EC50 30.0 nM
CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(OC(C)=O)cc1 CHEMBL1688091 IC50 31.0 nM
CCC(CC)(NC(=O)c1cnn2c1N[C@H](c1ccccc1)CC2(C)C)c1ccc(C)cc1 CHEMBL1688100 IC50 31.0 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@H](c1ccccc1)CC2(C)C)c1ccc(C)cc1 CHEMBL1689048 IC50 31.0 nM
Cc1cc(Cl)ccc1C(C)(O)c1nc2ccccc2s1 CHEMBL1256403 pEC50 31.62 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)N(C)[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)CO)cc2)C1)c1cccc2ccccc12 CHEMBL4082125 pEC50 31.62 nM
C[C@@H](NCC1CN(c2cccc(C(=O)O)c2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5397463 EC50 32.8 nM
C[C@@H](NCC1CN(c2ccccn2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5406483 EC50 33.3 nM
Cc1ccc([C@@H]2C[C@@H](CN[C@H](C)c3cccc4ccccc34)Oc3ccccc32)cc1C(=O)O CHEMBL5397226 EC50 33.6 nM
Cc1ccc(-c2c(C)nc(-c3cccc(F)c3O)n(CCc3ccccc3)c2=O)s1 CHEMBL4859029 IC50 35.0 nM
C[C@@H](NC[C@H]1C[C@@H](c2cccc(C(=O)O)c2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5440811 EC50 35.0 nM
C[C@@H](NC[C@H]1C[C@H](c2cccc(C(=O)O)c2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5425769 EC50 35.0 nM
O=C(Nc1nc(-c2ccccc2)cs1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL3093417 EC50 36.0 nM
C[C@@H](NCC1CN(c2cccc(OCC(=O)O)c2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5399168 EC50 36.4 nM
Cc1ccccc1C(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)C1CC1 CHEMBL1082788 IC50 37.0 nM
COc1ccc(CN[C@H](C)c2cccc(F)c2)cc1-c1ccc(C(F)(F)F)cc1 CHEMBL1224342 EC50 37.0 nM
N[C@@H](CCC(=O)Nc1cc(Cl)cc(S(=O)(=O)O)c1O)C(=O)NO CHEMBL3974015 EC50 39.0 nM
CSc1ccc(CC(C)(C)NC[C@@H](O)CO[C@H](C)c2ccc(C)c3c2[C@@H]2[C@H](O3)[C@H]2C(=O)O)cc1 CHEMBL3827209 IC50 39.3 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)NCCS(=O)(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4092377 pEC50 39.81 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)NC(CO)(CO)CO)cc2)C1)c1cccc2ccccc12 CHEMBL4074358 pEC50 39.81 nM
C[C@@H](N[C@H]1CCN(c2ccc(S(=O)(=O)NCC(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4094738 pEC50 39.81 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cnn2c1N[C@H](c1ccccc1)C[C@@H]2C(F)(F)F CHEMBL1289345 IC50 40.0 nM
COc1ccc2nc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)sc2c1 CHEMBL2377744 EC50 40.0 nM
N[C@@H](CSC(=O)Nc1cccc(S(=O)(=O)O)c1)C(=O)O CHEMBL3978873 EC50 40.0 nM
COc1cc([C@@H](C)N[C@H](C)c2cccc(Cl)c2)nn1-c1ccc(C(F)(F)F)cc1 CHEMBL571476 EC50 41.0 nM
COc1ccccc1C(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)C1CC1 CHEMBL1086281 IC50 41.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(Cc3ccc(OC)c(OC)c3)cc(OC)c21 CHEMBL1222490 IC50 43.0 nM
CCC(CC)(NC(=O)c1c(Cc2ccccc2)nn2c1NC(c1ccccc1)CC2(C)C)c1ccc(C)cc1 CHEMBL1689045 IC50 45.0 nM
Cc1ccc([C@@H](C)OC[C@H](O)CNC(C)(C)CC2Cc3ccccc3C2)c2c1O[C@H]1[C@H](C(=O)O)[C@@H]21 CHEMBL3828154 IC50 45.7 nM
Cc1c(C(=O)O)cccc1N1CC(CN[C@H](C)c2cccc3ccccc23)Oc2ccccc21 CHEMBL5432022 EC50 47.5 nM
COc1ccc([C@@H]2C[C@H](CN[C@H](C)c3cccc4ccccc34)Oc3ccccc32)cc1C(=O)O CHEMBL5400729 EC50 48.6 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@H](O)COc1cccc(Cl)c1C#N CHEMBL200311 IC50 50.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Cl)ccc(OC)c21 CHEMBL1223303 IC50 50.0 nM
C[C@@H](OC[C@H](O)CNC(C)(C)Cc1ccc(Cl)cc1F)c1ccccc1C1CC2CC1C1C(C(=O)O)C21 CHEMBL1783934 IC50 50.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)NCCCN3CCC(C(=O)O)CC3)cc2)C1)c1cccc2ccccc12 CHEMBL4071600 EC50 50.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)NCCO)cc2)C1)c1cccc2ccccc12 CHEMBL4126877 EC50 50.0 nM
Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1-c1ccc(-c2ccccn2)s1 CHEMBL4874182 IC50 50.0 nM
Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1-c1cc(-c2ccccn2)c(C)s1 CHEMBL4866668 IC50 50.0 nM
Cc1ccc([C@@H](C)OC[C@H](O)CNC(C)(C)CCSc2ccccc2)c2c1O[C@@H]1[C@@H](C(=O)O)[C@H]21 CHEMBL3827577 IC50 50.8 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(C(F)(F)F)ccc(OC)c21 CHEMBL1223369 IC50 51.0 nM
O=C(Nc1nc(-c2ccccc2)c(F)s1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL3093418 EC50 53.0 nM
C[C@@H](NCC1CN(c2ccccc2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5396763 EC50 53.4 nM
CC(C)(CC1Cc2ccccc2C1)NC[C@@H](O)COc1cc(C2CC3CC2C2C(C(=O)O)C32)cc(F)c1F CHEMBL1783762 IC50 56.0 nM
COc1cc([C@@H](C)N[C@H](C)c2cccc(Cl)c2)nn1-c1cccc(Cl)c1 CHEMBL577333 EC50 57.0 nM
COc1ccc(CN[C@H](C)c2ccc(F)cc2)cc1-c1ccc(C(F)(F)F)cc1 CHEMBL1224423 EC50 58.0 nM
Cc1ccc([C@H]2C[C@H](CN[C@H](C)c3cccc4ccccc34)Oc3ccccc32)cc1C(=O)O CHEMBL5420535 EC50 58.5 nM
Cc1ccc([C@@H](C)OC[C@H](O)CNC(C)(C)Cc2ccc(Cl)c(F)c2)c2c1O[C@@H]1[C@@H](C(=O)O)[C@H]21 CHEMBL3827154 IC50 58.7 nM
CC(C)(Cc1cc2ccccc2s1)NC[C@H](O)COc1ccccc1C#N CHEMBL199894 IC50 60.0 nM
COc1ccc(-c2nc(NCc3ccc4c(c3)OCO4)ccc2C(=O)NCCOc2ccccc2)c(OC)n1 CHEMBL457249 IC50 60.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(-c3ccccc3)cc(OC)c21 CHEMBL1222426 IC50 60.0 nM
Cn1nnc(-c2cccc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)c2)n1 CHEMBL2349575 EC50 60.0 nM
O=C(Nc1cccc(-c2cnco2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349603 EC50 60.0 nM
COC(=O)c1cccc(NC(=O)N(CCCN2CCNCC2)CCC(c2ccccc2)c2ccccc2)c1 CHEMBL2346788 EC50 60.0 nM
O=C(Nc1nc2ccc(Cl)cc2s1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377746 EC50 60.0 nM
O=C(Nc1nc2ccccc2[nH]1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377736 EC50 60.0 nM
Cc1ccc(C(C)OC[C@H](O)CNC(C)(C)Cc2ccc3ccccc3c2)c2c1OC1C(C(=O)O)C21 CHEMBL3827723 IC50 64.3 nM
C[C@@H](NCC1CN(c2ccc(C(=O)O)cc2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5394476 EC50 64.9 nM
COc1ccc(CC(C)(C)NC[C@@H](O)COc2cccc(Cl)c2Cl)cc1 CHEMBL487507 IC50 68.0 nM
COc1cc(-c2nc(NCc3cccc(Cl)c3)ncc2C(=O)NCCOc2ccccc2)cc(OC)c1OC CHEMBL493638 IC50 70.0 nM
COc1ccc(CC(C)(C)NCC(O)COc2cccc(Cl)c2C#N)cc1 CHEMBL523475 IC50 70.0 nM
COc1cc([C@@H](C)N[C@H](C)c2ccccc2)nn1-c1ccc(C(F)(F)F)cc1 CHEMBL569863 EC50 70.0 nM
C=CCNc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C CHEMBL599040 IC50 70.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(c1ccccc1)C1CC1 CHEMBL1083288 IC50 70.0 nM
C[C@@H](NCC1CN(c2cccc(CCC(=O)O)c2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5417460 EC50 70.4 nM
CC(C)(CC1Cc2ccccc2C1)NC[C@@H](O)COc1cc(CCC(=O)O)ccc1C#N CHEMBL1084513 IC50 73.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(c1ccccc1)C1CCC1 CHEMBL1083289 IC50 74.0 nM
COc1cc(-c2nc(N[C@H](CO)Cc3ccccc3)ccc2C(=O)NCCOc2ccccc2)cc(OC)c1OC CHEMBL457071 IC50 76.0 nM
C[C@H]1C[C@@H](c2ccccc2)Nc2c(C(=O)NC34CC5CC(CC(C5)C3)C4)cnn21 CHEMBL1290106 IC50 76.0 nM
Cc1ccc([C@@H](C)OC[C@H](O)CNC(C)(C)Cc2ccc(Cl)c(F)c2)c2c1O[C@H]1[C@H](C(=O)O)[C@@H]21 CHEMBL3827356 IC50 77.2 nM
Cc1ccc([C@@](C)(O)c2nc3ccccc3s2)c(C)c1 CHEMBL1256402 pEC50 79.43 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)NCC(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4068107 pEC50 79.43 nM
COc1cccc([C@@H](C)NCCCc2ccccc2Cl)c1 CHEMBL292376 EC50 80.0 nM
COc1cccc([C@@H](C)NCCCc2ccccc2Cl)c1 CHEMBL2107572 EC50 80.0 nM
CS(=O)(=O)c1ccc2nc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)sc2c1 CHEMBL2377752 EC50 80.0 nM
O=C(Nc1nc2ccc(CO)cc2s1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377747 EC50 80.0 nM
O=C(Nc1nc2cc(Cl)ccc2o1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377739 EC50 80.0 nM
Cc1cc(C)nc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2377727 EC50 80.0 nM
CCC(CC)(NC(=O)c1c(-c2ccccc2)nn2c1NC(c1ccccc1)CC2(C)C)c1ccc(C)cc1 CHEMBL1689044 IC50 81.0 nM
Cc1ccccc1[C@@H](OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)C1CC1 CHEMBL1085807 IC50 83.0 nM
Cc1cc(C(=O)O)cc(N2CC(CN[C@H](C)c3cccc4ccccc34)Oc3ccccc32)c1 CHEMBL5416437 EC50 84.1 nM
O=C(Nc1nc2ccc(OC(F)(F)F)cc2s1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377745 EC50 90.0 nM
C[C@@H](N[C@H](C)c1ccn(-c2ccc(C(F)(F)F)cc2)n1)c1cccc(Cl)c1 CHEMBL568485 EC50 92.0 nM
CCC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 CHEMBL1082711 IC50 92.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(CC(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4128835 EC50 93.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(CC(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4297621 EC50 93.0 nM
Cc1nc(-c2ccccc2O)n(CCc2cccc(F)c2)c(=O)c1C(C)C CHEMBL195711 IC50 95.0 nM
CCc1c(C)nc(-c2ccccc2O)n(CCc2ccccc2F)c1=O CHEMBL194764 IC50 97.0 nM
CCc1cc2c(=O)n(CCc3ccccc3F)c(-c3ccccc3O)nc2cc1C CHEMBL1083694 IC50 97.0 nM
O=C(OC12CC3CC(CC(C3)C1)C2)c1cnn2c1N[C@H](c1ccccc1)C[C@@H]2C(F)(F)F CHEMBL1289346 IC50 97.0 nM
CCc1c(C)nc(-c2ccccc2O)n(CCc2ccccc2)c1=O CHEMBL195859 IC50 100.0 nM
CC(C)(Cc1cc2ccccc2[nH]1)NC[C@H](O)COc1ccccc1C#N CHEMBL371936 IC50 100.0 nM
CC(O)(c1nc2ccccc2s1)c1ccc(Cl)cc1Cl CHEMBL1256404 pEC50 100.0 nM
CC(O)(c1ccc(Cl)c(Cl)c1)c1nc2ccccc2s1 CHEMBL1256303 pEC50 100.0 nM
COC(=O)c1cccc(NC(=O)N(CCCN2CCN(C)CC2)CCC(c2ccccc2)c2ccccc2)c1 CHEMBL2349577 EC50 100.0 nM
COC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2346786 EC50 100.0 nM
O=C(O)c1ccc2nc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)sc2c1 CHEMBL2375383 EC50 100.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)N[C@H](CCCCN)C(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4070562 pEC50 100.0 nM
C[C@@H](NCC1CN(c2cccc(CC(=O)O)c2)c2ccccc2O1)c1cccc2ccccc12 CHEMBL5406632 EC50 104.0 nM
C[C@@H](NCc1ccc(OC(F)(F)F)c(-c2ccc(C(F)(F)F)cc2)c1)c1ccccc1 CHEMBL1224426 EC50 110.0 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cnn2c1N[C@H](c1ccccc1Cl)C[C@@H]2C(F)(F)F CHEMBL1289573 IC50 110.0 nM
Cc1ccc(-c2nc(CCc3ccccc3)c(-c3cccc(F)c3O)nc2C)s1 CHEMBL4857145 IC50 110.0 nM
Cc1ccc(C(C)OC[C@H](O)CNC(C)(C)CC2Cc3ccccc3C2)c2c1OC1C(C(=O)O)C21 CHEMBL3827912 IC50 117.3 nM
Cc1nc(-c2ccccc2O)n(CCc2cccc(F)c2)c(=O)c1C1CC1 CHEMBL195305 IC50 120.0 nM
C#CCN(CC#C)c1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C CHEMBL597812 IC50 120.0 nM
COc1ccccc1C(C)OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1 CHEMBL1083313 IC50 120.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(OC(F)(F)F)cc2)C1)c1cccc2ccccc12 CHEMBL4129011 EC50 120.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)NCC[N+](C)(C)C)cc2)C1)c1cccc2ccccc12 CHEMBL4062970 pEC50 125.89 nM
COc1cc(-c2nc(NCc3ccc4c(c3)OCO4)ccc2C(=O)NCCOc2ccccc2)cc(OC)c1OC CHEMBL451383 IC50 130.0 nM
CSc1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349590 EC50 130.0 nM
Cc1ccc(C(=O)O)cc1N1CC(CN[C@H](C)c2cccc3ccccc23)Oc2ccccc21 CHEMBL5397798 EC50 138.0 nM
CCCc1c(C)nc(-c2ccccc2O)n(CCc2cccc(F)c2)c1=O CHEMBL195566 IC50 140.0 nM
O=C1C2CCCCC2N=C(c2ccccc2O)N1CCc1ccccc1 CHEMBL369998 IC50 140.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc([N+](=O)[O-])c1O CHEMBL372321 IC50 140.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc(F)c1O CHEMBL199495 IC50 140.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc([N+](=O)[O-])c1 CHEMBL372820 IC50 140.0 nM
COc1ccc(-c2nc(N[C@H](CO)Cc3ccccc3)ccc2C(=O)NCCOc2ccccc2)c(OC)n1 CHEMBL515828 IC50 140.0 nM
COc1ccc(CC(C)(C)NCC(O)COc2ccccc2C#N)cc1 CHEMBL504479 IC50 140.0 nM
CC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1Cl CHEMBL1083307 IC50 140.0 nM
Cc1ccc(C(C)OC[C@H](O)CNC(C)(C)Cc2ccc3ccccc3c2)cc1 CHEMBL1082999 IC50 140.0 nM
CC(C)(CC1Cc2ccccc2C1)NC[C@@H](O)COc1cc(CCC(=O)O)cc(F)c1F CHEMBL1198855 IC50 146.0 nM
C[C@@H](N[C@H](C)c1ccn(-c2ccc(C(F)(F)F)cc2)n1)c1cccc(F)c1 CHEMBL572363 EC50 148.0 nM
COc1cc(-c2nc(NCc3ccc4c(c3)OCO4)ncc2C(=O)NCCOc2ccccc2)cc(OC)c1OC CHEMBL509410 IC50 150.0 nM
COc1cc(-c2nc(N[C@H](CO)Cc3ccccc3)ncc2C(=O)NCCOc2ccccc2)cc(OC)c1OC CHEMBL495263 IC50 150.0 nM
COc1ccc(-c2nc(NCc3ccc4c(c3)OCO4)ncc2C(=O)NC(C)Cc2ccc(Cl)cc2)c(OC)n1 CHEMBL454385 IC50 150.0 nM
CCCC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 CHEMBL1082306 IC50 150.0 nM
CC1(C)CC(c2ccccc2)Nc2c(C(=O)NC(c3ccc(C(F)(F)F)cc3)(C3CCCCC3)C3CCCCC3)cnn21 CHEMBL1689814 IC50 150.0 nM
O=C(Nc1cccc(-c2nc3ccccc3s2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349573 EC50 150.0 nM
Cc1cc(-c2cccc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)c2)on1 CHEMBL2349604 EC50 150.0 nM
O=C(Nc1cccc(-c2ccco2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349602 EC50 150.0 nM
CCC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349586 EC50 150.0 nM
O=C(OCCO)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349584 EC50 150.0 nM
CC(C)OC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349580 EC50 150.0 nM
COC(=O)c1cccc(NC(=O)N(CCCN2CCOCC2)CCC(c2ccccc2)c2ccccc2)c1 CHEMBL2346787 EC50 150.0 nM
Cn1c(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)nc2ccccc21 CHEMBL2377737 EC50 150.0 nM
CCN(Cc1ccccc1)c1ccc(C(=O)NCCOc2ccccc2)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL454386 IC50 154.0 nM
N#Cc1sc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)nc1-c1ccccc1 CHEMBL3091483 EC50 157.0 nM
Cc1cc(C(C)(O)c2nc3ccccc3s2)ccc1F CHEMBL1256366 pEC50 158.49 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4079960 pEC50 158.49 nM
O=C1C2CCCCC2N=C(c2ccccc2O)N1CCc1cccc(F)c1 CHEMBL194490 IC50 160.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1ccccc1[N+](=O)[O-] CHEMBL197863 IC50 160.0 nM
CC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1C#N CHEMBL1082787 IC50 160.0 nM
COc1ccc(CNC(C)c2cccc(C)c2)cc1-c1ccc(C(F)(F)F)cc1 CHEMBL1224343 EC50 160.0 nM
COc1cc(-c2nc(NCc3cccc(Cl)c3)ccc2C(=O)NCCOc2ccccc2)cc(OC)c1OC CHEMBL514434 IC50 162.0 nM
Cc1nc(-c2ccccc2O)n(CCc2cccc(F)c2)c(=O)c1C CHEMBL193498 IC50 170.0 nM
CC#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C CHEMBL591241 IC50 170.0 nM
CCCCC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 CHEMBL1082718 IC50 170.0 nM
Cc1cccc(C(C)OC[C@H](O)CNC(C)(C)Cc2ccc3ccccc3c2)c1 CHEMBL1082998 IC50 170.0 nM
O=C(Nc1nsc(-c2ccccc2)n1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL3093415 EC50 175.0 nM
C=CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C CHEMBL599228 IC50 180.0 nM
Cc1nnc([C@@H](N)CCC(=O)Nc2cc(Cl)cc(S(=O)(=O)O)c2O)o1 CHEMBL3943365 EC50 180.0 nM
O=c1c2cc(F)ccc2nc(-c2ccccc2O)n1CCc1cccc(F)c1 CHEMBL180463 IC50 190.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc(C#N)c1 CHEMBL199716 IC50 190.0 nM
COc1ccc(Br)c2nc(-c3ccc(C(C)C)cc3)n(CCN(C)C)c12 CHEMBL1223438 IC50 190.0 nM
CCc1cc(OC)c2c(nc(-c3ccc(C(C)C)cc3)n2CCOC)c1Br CHEMBL1222424 IC50 190.0 nM
C[C@@H](N[C@@H]1CCCN(c2cccc(OC(F)(F)F)c2)C1)c1cccc2ccccc12 CHEMBL4128542 EC50 190.0 nM
COc1ccc(-c2nc(NCc3cccc(Cl)c3)ccc2C(=O)NCCOc2ccccc2)c(OC)n1 CHEMBL460726 IC50 197.0 nM
Cc1ccc(C(O)(c2nc3ccccc3s2)C2CC2)c(C)c1 CHEMBL1258389 pEC50 199.53 nM
Cc1nc(-c2ccccc2O)n(CCc2ccccc2)c(=O)c1C CHEMBL371828 IC50 200.0 nM
O=C1C2CCCC2N=C(c2ccccc2O)N1CCc1ccccc1 CHEMBL370503 IC50 200.0 nM
O=C1C2CCCC2N=C(c2ccccc2O)N1CCc1cccc(F)c1 CHEMBL195375 IC50 200.0 nM
CCN(Cc1ccccc1)c1ncc(C(=O)NCCOc2ccccc2)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL508063 IC50 200.0 nM
COc1ccc(CC(C)(C)NCC(O)COc2cccc(Cl)c2Cl)cc1 CHEMBL491251 IC50 200.0 nM
CC(C)C(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 CHEMBL1082717 IC50 200.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(c1ccccc1)C1CCCC1 CHEMBL1084200 IC50 200.0 nM
Cc1ccccc1C(C)OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1 CHEMBL1083610 IC50 200.0 nM
Cn1nnnc1-c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349576 EC50 200.0 nM
O=C(Nc1cccc(-c2cccnc2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349601 EC50 200.0 nM
O=C(Nc1cccc(-c2ccccc2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349600 EC50 200.0 nM
O=C(Nc1cccc(OC(F)(F)F)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349595 EC50 200.0 nM
O=C(OCc1ccccc1)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349581 EC50 200.0 nM
O=C(Nc1nc2ccc(F)cc2s1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2375386 EC50 200.0 nM
CN(C)CCNC(=O)c1ccc2nc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)sc2c1 CHEMBL2377751 EC50 200.0 nM
CCOC(=O)c1ccc2nc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)sc2c1 CHEMBL2377750 EC50 200.0 nM
Cc1cc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)no1 CHEMBL2377732 EC50 200.0 nM
O=C(Nc1nccc(-c2nccs2)n1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377730 EC50 200.0 nM
Cc1ccc(C(C)OC[C@H](O)CNC(C)(C)Cc2ccc(Cl)c(F)c2)c2c1OC1C(C(=O)O)C21 CHEMBL3828182 IC50 202.7 nM
O=c1c2cc(F)ccc2nc(-c2ccccc2O)n1CCc1ccccc1 CHEMBL183287 IC50 210.0 nM
CC(C)(Cc1cccc2ccccc12)NCC(O)COc1ccccc1 CHEMBL488736 IC50 210.0 nM
C=CC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 CHEMBL1082712 IC50 210.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(C)ccc(OC)c21 CHEMBL1223439 IC50 210.0 nM
COc1ccc(-c2nc(NCc3ccc4c(c3)OCO4)ncc2C(=O)NCCOc2ccccc2)c(OC)n1 CHEMBL458516 IC50 220.0 nM
CC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 CHEMBL1084757 IC50 220.0 nM
CC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1cccc(Cl)c1 CHEMBL1083308 IC50 220.0 nM
C=CCN(C)c1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C CHEMBL610511 IC50 230.0 nM
C[C@@H](N[C@@H]1CCN(c2ccc(OC(F)(F)F)cc2)C1)c1cccc2ccccc12 CHEMBL4129371 EC50 230.0 nM
C[C@@H](N[C@H](C)c1ccn(-c2ccc(C(F)(F)F)cc2)n1)c1ccccc1 CHEMBL583522 EC50 233.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc(Cl)c1C#N CHEMBL203479 IC50 240.0 nM
Cc1cccc2nc(-c3ccccc3O)n(CCc3ccccc3)c(=O)c12 CHEMBL361623 IC50 250.0 nM
Cc1cccc2nc(-c3ccccc3O)n(CCc3cccc(F)c3)c(=O)c12 CHEMBL360226 IC50 250.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1ccc(C#N)cc1 CHEMBL199548 IC50 250.0 nM
N[C@@H](CCC(=O)Nc1cc(Cl)cc(S(=O)(=O)O)c1O)C(=O)NNC(=O)Cc1ccccc1 CHEMBL3971904 EC50 250.0 nM
Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1Cc1ccccc1 CHEMBL4866041 IC50 250.0 nM
Cc1nc(-c2cccc(F)c2O)n(CCc2ccccc2)c(=O)c1-c1ccc(-c2ccccc2)s1 CHEMBL4860070 IC50 250.0 nM
Cc1ccccc1C(C)(O)c1nc2ccccc2s1 CHEMBL1256331 pEC50 251.19 nM
CC(C)(Cc1cc2ccccc2s1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc(C#N)c1 CHEMBL200312 IC50 270.0 nM
CN(C[C@@H](O)COc1cccc(Cl)c1C#N)C(C)(C)Cc1ccc2ccccc2c1 CHEMBL370811 IC50 270.0 nM
COc1cccc([C@@H](C)NCc2ccc(Cl)c(-c3ccc(C(F)(F)F)cc3)c2)c1 CHEMBL1224344 EC50 280.0 nM
O=C(Nc1nnc(-c2ccccc2)s1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL3093414 EC50 286.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4126482 EC50 290.0 nM
O=c1c2cc(Cl)ccc2nc(-c2ccccc2O)n1CCc1ccccc1 CHEMBL361333 IC50 300.0 nM
O=c1c2ccccc2nc(-c2ccccc2O)n1CCc1ccccc1 CHEMBL180030 IC50 300.0 nM
COc1ccc(CC(C)(C)NC[C@H](O)COc2cccc(Cl)c2Cl)cc1 CHEMBL487508 IC50 300.0 nM
CC(CCOC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 CHEMBL1083951 IC50 300.0 nM
Cc1ccc(CC(C)(C)NC[C@@H](O)COc2cc(C3CC4CC3C3C(C(=O)O)C43)ccc2F)cc1F CHEMBL1783766 IC50 300.0 nM
O=C(Nc1cccc(-c2nccs2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349605 EC50 300.0 nM
CN(C)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349599 EC50 300.0 nM
COc1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349598 EC50 300.0 nM
CC(C)(C)OC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349583 EC50 300.0 nM
O=C(Nc1nc2ccccc2n1Cc1ccccc1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377738 EC50 300.0 nM
O=C(Nc1nccs1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377731 EC50 300.0 nM
O=C(Nc1cccc(-c2ccccc2)n1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL3093412 EC50 300.0 nM
C[C@@H](NCc1cc2ccccc2[nH]1)c1cccc2ccccc12 CHEMBL2092942 EC50 310.0 nM
Cc1ccccc1[C@H](OC[C@@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)C1CC1 CHEMBL1085334 IC50 310.0 nM
CN[C@@H](CNC(=O)Nc1cc(Cl)c(C)c(S(=O)(=O)O)c1)C(=O)O CHEMBL3974155 EC50 313.0 nM
Cc1cc(C)c2c(c1)C(O)(c1nc3ccccc3s1)CCC2 CHEMBL1255602 pEC50 316.23 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cnn2c1N[C@H](c1cccc(Cl)c1)C[C@@H]2C(F)(F)F CHEMBL1289679 IC50 320.0 nM
CCC(CC)(NC(=O)c1c(C)nn2c1N[C@@H](c1ccccc1)CC2(C)C)c1ccc(C(=O)O)cc1 CHEMBL1689061 IC50 320.0 nM
C[C@@H](N[C@@H]1CCN(c2cccc(OC(F)(F)F)c2)C1)c1cccc2ccccc12 CHEMBL4126057 EC50 320.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1ccccc1C#N CHEMBL200361 IC50 340.0 nM
COc1cccc(CNc2ncc(C(=O)NCCOc3ccccc3)c(-c3cc(OC)c(OC)c(OC)c3)n2)c1 CHEMBL493228 IC50 340.0 nM
COc1ccccc1CCNc1ncc(C(=O)NCCOc2ccccc2)c(-c2cc(OC)c(OC)c(OC)c2)n1 CHEMBL494442 IC50 340.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(Cc3ccc(C)c(C)c3)cc(OC)c21 CHEMBL1222491 IC50 340.0 nM
COc1cccc([C@@H](C)NCc2cccc(-c3ccccc3Cl)c2)c1 CHEMBL1224192 EC50 350.0 nM
CC(C)(CN1Cc2ccccc2C1=O)NC[C@@H](O)COc1cc(C2CC3CC2C2C(C(=O)O)C32)ccc1C#N CHEMBL1783932 IC50 350.0 nM
O=C(Nc1cccc(SC(F)(F)F)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349591 EC50 350.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc(F)c1F CHEMBL200690 IC50 360.0 nM
CCN(Cc1ccccc1)c1ncc(C(=O)NCCOc2ccccc2)c(-c2ccc(OC)nc2OC)n1 CHEMBL462661 IC50 360.0 nM
COc1ccc(-c2nc(NCc3ccc4c(c3)OCO4)ncc2C(=O)N2CCc3ccccc3C2)c(OC)n1 CHEMBL458515 IC50 360.0 nM
CC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1cccc2ccccc12 CHEMBL1082710 IC50 360.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2cc(C(F)(F)F)cc(OC)c21 CHEMBL1222425 IC50 360.0 nM
COc1ccc(CN[C@H](C)c2cccc(OC)c2)cc1 CHEMBL1224193 EC50 370.0 nM
O=C(NC(c1ccccc1)c1ccccc1)c1cnn2c1N[C@H](c1ccccc1)C[C@@H]2C(F)(F)F CHEMBL1688102 IC50 380.0 nM
C[C@@H](N[C@@H]1CCCN(c2cccc(C(F)(F)F)c2)C1)c1cccc2ccccc12 CHEMBL4125917 EC50 380.0 nM
CS(=O)(=O)NC(=O)[C@@H](N)CCC(=O)Nc1cc(Cl)cc(S(=O)(=O)O)c1O CHEMBL3957364 EC50 390.0 nM
CC(O)(c1ccc(Cl)cc1)c1nc2ccccc2s1 CHEMBL1256301 pEC50 398.11 nM
C[C@@H](N[C@H]1CCN(c2ccc(C(=O)N[C@H](CC(=O)O)C(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4097717 pEC50 398.11 nM
COc1cc(-c2nc(NCCc3ccccc3)ncc2C(=O)NCCOc2ccccc2)cc(OC)c1OC CHEMBL494647 IC50 400.0 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cnn2c1N[C@H](c1ccco1)C[C@@H]2C(F)(F)F CHEMBL1289892 IC50 400.0 nM
O=C(Nc1cccc(C(F)(F)F)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349597 EC50 400.0 nM
O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349594 EC50 400.0 nM
COCc1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349589 EC50 400.0 nM
O=C(OCCCC(F)(F)C(F)(F)F)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349585 EC50 400.0 nM
COC(=O)c1cccc(NC(=O)N(CCCN2CCN(C(=O)OC)CC2)CCC(c2ccccc2)c2ccccc2)c1 CHEMBL2349578 EC50 400.0 nM
COC(=O)c1sccc1NC(=O)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377734 EC50 400.0 nM
COc1cc(C)nc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)n1 CHEMBL2377729 EC50 400.0 nM
CC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccn1 CHEMBL1086472 IC50 420.0 nM
C[C@@H](N[C@@H]1CCN(c2cccc(C(F)(F)F)c2)C1)c1cccc2ccccc12 CHEMBL4125688 EC50 430.0 nM
CC(C)(Cc1cc2ccccc2[nH]1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc(C#N)c1 CHEMBL538155 IC50 440.0 nM
CC(Cc1ccccc1)OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1 CHEMBL1083950 IC50 440.0 nM
O=C(Nc1cnccn1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377728 EC50 450.0 nM
C[C@@H](N[C@H]1CCN(c2cccc(C(F)(F)F)c2)C1)c1cccc2ccccc12 CHEMBL4127153 EC50 450.0 nM
Cc1ccc([C@@H](C)OC[C@H](O)CNC(C)(C)Cc2ccc3ncccc3c2)c2c1O[C@@H]1[C@@H](C(=O)O)[C@H]21 CHEMBL3827410 IC50 457.1 nM
CCNc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C CHEMBL589977 IC50 460.0 nM
COc1cc(-c2nc(N(C)Cc3ccccc3)ncc2C(=O)NCCOc2ccccc2)cc(OC)c1OC CHEMBL510598 IC50 470.0 nM
Cc1ccc([C@@H](C)OC[C@H](O)CN2CCCC2Cc2ccccc2)c2c1O[C@@H]1[C@@H](C(=O)O)[C@H]21 CHEMBL3827473 IC50 489.1 nM
N[C@@H](CNC(=O)Nc1cc(S(=O)(=O)O)ccc1F)C(=O)O CHEMBL3950758 EC50 490.0 nM
C[C@@H](N[C@H]1CCN(c2ccc(S(=O)(=O)NC(=O)CCC(=O)O)cc2)C1)c1cccc2ccccc12 CHEMBL4091950 pEC50 501.19 nM
Cc1ccc2nc(-c3ccccc3O)n(CCc3cccc(F)c3)c(=O)c2c1 CHEMBL180057 IC50 520.0 nM
CCN(CC)c1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C CHEMBL599857 IC50 520.0 nM
CCOC(=O)CCc1ccc(C#N)c(OC[C@H](O)CNC(C)(C)CC2Cc3ccccc3C2)c1 CHEMBL1084514 IC50 520.0 nM
CC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1[N+](=O)[O-] CHEMBL1083314 IC50 540.0 nM
CC(OC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccc2ccccc2c1 CHEMBL1082379 IC50 550.0 nM
CC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349587 EC50 550.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COCc1ccccc1 CHEMBL1084756 IC50 560.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(c1ccccc1)C(C)(C)C CHEMBL1082719 IC50 570.0 nM
CC1(C)C=C(c2ccccc2)Nc2c(C(=O)NC34CC5CC(CC(C5)C3)C4)cnn21 CHEMBL1290329 IC50 580.0 nM
O=c1c2ccc(F)cc2nc(-c2ccccc2O)n1CCc1ccccc1 CHEMBL361316 IC50 600.0 nM
CC(C)(Cc1ccc(F)cc1)NC[C@@H](O)COc1cccc(Cl)c1C#N CHEMBL199363 IC50 600.0 nM
O=C(Nc1cccc(Nc2nc3ccccc3[nH]2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2346765 EC50 600.0 nM
Cc1cccc2sc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)nc12 CHEMBL2377742 EC50 600.0 nM
C[C@@H](N[C@H]1CCCN(c2cccc(OC(F)(F)F)c2)C1)c1cccc2ccccc12 CHEMBL4130093 EC50 600.0 nM
C[C@@H](N[C@H]1CCN(c2cccc(OC(F)(F)F)c2)C1)c1cccc2ccccc12 CHEMBL4125724 EC50 600.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(c1ccccc1)C1CCCCC1 CHEMBL1084201 IC50 610.0 nM
COc1cccc([C@@H](C)NCc2cccc(-c3ccc(C(F)(F)F)cc3)c2)c1 CHEMBL1224264 EC50 620.0 nM
CC(O)(c1ccc2ccccc2c1)c1nc2ccccc2s1 CHEMBL1258390 pEC50 630.96 nM
Cc1ncc(-c2c(C)nc(-c3cccc(F)c3O)n(CCc3ccccc3)c2=O)s1 CHEMBL4851971 IC50 631.0 nM
Cc1cccc2c(=O)n(CCc3ccccc3)c(-c3ccccc3O)nc12 CHEMBL179907 IC50 700.0 nM
O=C(NC12CC3CC(CC(C3)C1)C2)c1cnn2c1N[C@H](c1ccccc1)C[C@@H]2c1ccccc1 CHEMBL1290007 IC50 700.0 nM
COc1cc(-c2nc(NCc3ccccc3)ncc2C(=O)NCCOc2ccccc2)cc(OC)c1OC CHEMBL454374 IC50 730.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(c1ccccc1)c1ccccc1 CHEMBL1083306 IC50 730.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1cccc(F)c1 CHEMBL201137 IC50 750.0 nM
Cc1ccccc1[C@@H](OC[C@@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)C1CC1 CHEMBL1085335 IC50 760.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(OC)ccc(Cl)c21 CHEMBL1223371 IC50 770.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1ccc([N+](=O)[O-])cc1 CHEMBL199529 IC50 790.0 nM
CCCn1c(-c2ccc(C(C)C)cc2)nc2c(C)ccc(OC)c21 CHEMBL1223440 IC50 790.0 nM
O=c1c2ccccc2nc(-c2ccccc2O)n1CCc1cccc(Cl)c1 CHEMBL180250 IC50 800.0 nM
Cc1c(C(F)(F)F)nc(-c2ccccc2O)n(CCc2ccccc2)c1=O CHEMBL195045 IC50 800.0 nM
N#Cc1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349596 EC50 800.0 nM
C[S+]([O-])c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349592 EC50 800.0 nM
O=C(Nc1cccc(CO)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349588 EC50 800.0 nM
COC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CC(=O)OC(C)(C)C)c1 CHEMBL2346784 EC50 800.0 nM
CC(COC[C@H](O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 CHEMBL1085987 IC50 810.0 nM
COc1ccc(-c2cccc(CN[C@H](C)c3cccc(OC)c3)c2)cc1 CHEMBL1224263 EC50 870.0 nM
CC(C)(Cc1ccc2ccccc2c1)NCCCOc1cccc(Cl)c1C#N CHEMBL199785 IC50 880.0 nM
N[C@@H](CCC(=O)Nc1cc(Cl)cc(S(=O)(=O)O)c1O)c1nnc(Cc2ccccc2)o1 CHEMBL3897239 EC50 880.0 nM
CC(C)(CC1Cc2ccccc2C1)NC[C@@H](O)COc1cccc(C2CC3CC2C2C(C(=O)O)C32)c1 CHEMBL1783763 IC50 900.0 nM
COc1ccc(CC(C)(C)NCCCOc2cccc(Cl)c2Cl)cc1 CHEMBL520396 IC50 930.0 nM
COc1ccc(CC(C)(C)NCC(COc2cccc(Cl)c2Cl)OC)cc1 CHEMBL488738 IC50 950.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)COC(c1cccc(C(=O)O)c1)C1CC1 CHEMBL1672962 IC50 960.0 nM
CC(C)(Cc1ccc2ccccc2c1)NC[C@@H](O)[C@H]1CCCN1Cc1ccccc1O CHEMBL201085 IC50 970.0 nM
CC(C)(Cc1csc2ccccc12)NC[C@@H](O)[C@H]1CCCN1Cc1cccc(C#N)c1 CHEMBL200041 IC50 1000.0 nM
COc1cccc(CCNc2ncc(C(=O)NCCOc3ccccc3)c(-c3cc(OC)c(OC)c(OC)c3)n2)c1 CHEMBL494441 IC50 1000.0 nM
COc1ccc(CC(C)(C)NCC(O)COc2ccccc2Cl)cc1 CHEMBL488997 IC50 1000.0 nM
COc1ccc(CC(C)(C)NCC(O)COc2cccc(Cl)c2)cc1 CHEMBL521907 IC50 1000.0 nM
COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)ccc(Br)c21 CHEMBL1223437 IC50 1000.0 nM
O=C(Nc1cccc(Nc2nnn[nH]2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2349574 EC50 1000.0 nM
CS(=O)(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 CHEMBL2349593 EC50 1000.0 nM
CC(OC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1)C(C)(C)C CHEMBL2349582 EC50 1000.0 nM
CC(NCCC(c1ccccc1)c1ccccc1)c1ccccc1 CHEMBL254832 EC50 1000.0 nM
CCOc1ccc2nc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)sc2c1 CHEMBL2375385 EC50 1000.0 nM
O=C(Nc1cccnc1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 CHEMBL2377726 EC50 1000.0 nM
COc1ccc(S(=O)(=O)O)cc1NC(=O)NC[C@H](N)C(=O)O CHEMBL3964061 EC50 1000.0 nM
N[C@@H](CNC(=O)Nc1cccc(C(=O)O)c1O)C(=O)O CHEMBL3937957 EC50 1000.0 nM