C[C@H]1C(=O)N(C)C=Cc2cc(OCCCCOc3ccc4c(c3)C=CN(C)C(=O)[C@@H]4C)ccc21 CHEMBL5426022 pIC50 0.03981 nM
C[C@H]1C(=O)N(C)C=Cc2cc(OCCOc3ccc4c(c3)C=CN(C)C(=O)[C@@H]4C)ccc21 CHEMBL5422047 pIC50 0.2512 nM
COc1nnc2ccc(N3CCC(c4ccc(OCCN5CCN(C)C(=O)[C@H]5C)cc4)CC3)nn12 CHEMBL4078100 pIC50 3.162 nM
C[C@H]1C(=O)N(C)C=Cc2cc(CN3CCN(Cc4ccc5c(c4)C=CN(C)C(=O)[C@@H]5C)CC3)ccc21 CHEMBL5433432 pIC50 6.31 nM
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)OC(C)(C)C)c1nnc(C)n1-2 CHEMBL1957266 pIC50 6.31 nM
COCC(COC)n1c(-c2cc(C)c(=O)n(C)c2)nc2cc(N3CCOCC3)ccc21 CHEMBL4438171 pIC50 7.943 nM
C[C@H]1C(=O)N(C)C=Cc2cc(OCCCCCOc3ccc4c(c3)C=CN(C)C(=O)[C@@H]4C)ccc21 CHEMBL5403564 pIC50 12.59 nM
CCOc1ccc2c(c1)C(c1c[nH]c(C)n1)=CN(C)C(=O)[C@@H]2C CHEMBL5220494 pIC50 15.85 nM
Cc1cc2c(-c3ccco3)cnc(N[C@@H]3CCN(C)C[C@H]3C(=O)NC3CCCCC3)c2[nH]c1=O CHEMBL4648362 pIC50 19.95 nM
CCOc1ccc2c(c1)C(c1cnn(C)c1)=CN(C)C(=O)[C@@H]2C CHEMBL5219991 pIC50 19.95 nM
CCOc1ccc2c(c1)C(c1cn[nH]c1)=CN(C)C(=O)[C@@H]2C CHEMBL5218813 pIC50 25.12 nM
CC(=O)Nc1c(F)cc(C(=O)N[C@H]2CC[C@H](O)CC2)cc1O[C@@H](C)c1ccccc1 CHEMBL4636881 pIC50 31.62 nM
C[C@H]1C(=O)N(C)C=C(c2cn[nH]c2)c2cc([C@@H](O)CO)ccc21 CHEMBL5220128 pIC50 31.62 nM
C[C@H]1C(=O)N(C)C=C(c2cnn(C)c2)c2cc(C(CO)CO)ccc21 CHEMBL5219919 pIC50 31.62 nM
CCS(=O)(=O)c1ccc2c(c1)C(c1cnn(C)c1)=CN(C)C(=O)[C@@H]2C CHEMBL5218822 pIC50 39.81 nM
C[C@H]1C(=O)N(C)C=C(c2cn[nH]c2)c2cc([C@H](O)CO)ccc21 CHEMBL5218726 pIC50 39.81 nM
C[C@H]1C(=O)N(C)C=C(c2cnn(C)c2)c2cc([C@H](O)CO)ccc21 CHEMBL5218909 pIC50 39.81 nM
C[C@H]1C(=O)N(C)C=C(c2cnn(C)c2)c2cc([C@@H](O)CO)ccc21 CHEMBL5219602 pIC50 39.81 nM
Cc1nc(C2=CN(C)C(=O)[C@H](C)c3ccc(OCCO)cc32)c[nH]1 CHEMBL5219538 pIC50 39.81 nM
COc1cc2c(cc1-c1c(C)noc1C)ncc1[nH]c(=O)n([C@H](C)c3ccccn3)c12 CHEMBL2017291 pIC50 39.81 nM
COCc1nc2cnc3cc(-c4c(C)noc4C)c(OC[C@H]4CCNC4)cc3c2n1[C@H](C)c1ccccc1 CHEMBL4639128 pIC50 39.81 nM
CNC(=O)c1cc(C(=O)N[C@H]2[C@@H]3COC[C@@H]32)cc2c1O[C@H](CF)[C@H]2c1ccccc1 CHEMBL4637208 pIC50 50.12 nM
CCOc1ccc2c(c1)C(c1c[nH]cn1)=CN(C)C(=O)[C@@H]2C CHEMBL5221069 pIC50 50.12 nM
CCOc1ccc2c(c1)C(c1cn(C)cn1)=CN(C)C(=O)[C@@H]2C CHEMBL5218817 pIC50 50.12 nM
C[C@H]1C(=O)N(C)C=Cc2cc(OCCCOc3ccc4c(c3)C=CN(C)C(=O)[C@@H]4C)ccc21 CHEMBL5426762 pIC50 50.12 nM
COc1cc2c(cc1OC)[C@@H](C)C(=O)N(C)C=C2 CHEMBL5220623 pIC50 50.12 nM
CNC(=O)c1cc(C(=O)NC2CC2)cn(Cc2ccccc2)c1=O CHEMBL4635134 pIC50 63.1 nM
C[C@H]1C(=O)N(C)C=Cc2cc(OCCCCCCCOc3ccc4c(c3)C=CN(C)C(=O)[C@@H]4C)ccc21 CHEMBL5408181 pIC50 79.43 nM
CCOc1ccc2c(c1)C(c1cc[nH]n1)=CN(C)C(=O)C2C CHEMBL5219194 pIC50 125.89 nM
CCS(=O)(=O)c1ccc2c(c1)C(C)=CN(C)C(=O)[C@@H]2C CHEMBL5219077 pIC50 158.49 nM
CC(=O)N1c2ccc(C(N)=O)cc2[C@H](Nc2ncc(Cl)cn2)C[C@@H]1C CHEMBL5195288 pIC50 199.53 nM
C[C@@H]1C(=O)N(C)CCN1CCOc1ccc(C2CCN(c3ccc4nncn4n3)CC2)cc1 CHEMBL4519518 pIC50 199.53 nM
CCNC(=O)c1ccc2c(c1)[C@H](Nc1ccc(C#N)cn1)C[C@H](C)N2C(C)=O CHEMBL5190509 pIC50 251.19 nM
CC(=O)N1c2ccc(C(N)=O)cc2[C@H](Nc2ccc(Cl)cn2)C[C@@H]1C CHEMBL5194720 pIC50 398.11 nM
C[C@H]1C(=O)N(C)C=Cc2cc(CN3CCOCC3)ccc21 CHEMBL5220077 pIC50 398.11 nM
CCS(=O)(=O)c1ccc2c(c1)C=CN(C)C(=O)[C@@H]2C CHEMBL5220099 pIC50 398.11 nM
CC1C(=O)N(C)C=Cc2cc(OCC(C)(C)O)ccc21 CHEMBL5220904 pIC50 630.96 nM
C[C@H]1C(=O)N(C)C=Cc2cc(OC(CO)CO)ccc21 CHEMBL5220501 pIC50 630.96 nM
C[C@H]1C(=O)N(C)C=Cc2cc(CC3CCOCC3)ccc21 CHEMBL5220753 pIC50 630.96 nM
C[C@H]1C(=O)N(C)C=Cc2cc(C(CO)CO)ccc21 CHEMBL5220275 pIC50 630.96 nM
COCCOc1ccc2c(c1)C=CN(C)C(=O)[C@@H]2C CHEMBL5218922 pIC50 1000.0 nM
C[C@H]1C(=O)N(C)C=Cc2cc(CCO)ccc21 CHEMBL5219089 pIC50 1000.0 nM
C[C@H]1C(=O)N(C)C=Cc2cc(C(O)CO)ccc21 CHEMBL5219599 pIC50 1000.0 nM