Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(CC(F)(F)F)CC3)C[C@H]2C1 CHEMBL1270493 IC50 17.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CN(S(=O)(=O)C4CCCC4)C3)C[C@H]2C1 CHEMBL1270595 IC50 22.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CN(S(=O)(=O)C(C)C)C3)C[C@H]2C1 CHEMBL1270101 IC50 23.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(=O)(=O)C4CCCC4)CC3)C[C@H]2C1 CHEMBL1269384 IC50 23.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3cc(F)cc(F)c3)C3CCN(CC(F)F)CC3)C[C@H]2C1 CHEMBL1270798 IC50 25.0 nM
CCS(=O)(=O)N1CCC(C(CCN2C[C@@H]3CN(C(=O)c4c(C)ncnc4C)C[C@@H]3C2)c2ccccc2)CC1 CHEMBL1270799 IC50 25.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(C)(=O)=O)CC3)C[C@H]2C1 CHEMBL1270901 IC50 25.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(CC(F)F)CC3)C[C@H]2C1 CHEMBL1270594 IC50 27.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(=O)(=O)C4CC4)CC3)C[C@H]2C1 CHEMBL1270694 IC50 27.0 nM
Cc1cc(=O)oc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(C)(=O)=O)CC3)C[C@H]2C1 CHEMBL1271108 IC50 27.0 nM
Cc1cc(C#N)nc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(C)(=O)=O)CC3)C[C@H]2C1 CHEMBL1271208 IC50 31.0 nM
CCC(=O)N1CCC(C(CCN2C[C@@H]3CN(C(=O)c4c(C)ncnc4C)C[C@@H]3C2)c2ccccc2)CC1 CHEMBL1271107 IC50 32.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3cccc(F)c3)C3CCN(S(C)(=O)=O)CC3)C[C@H]2C1 CHEMBL1269885 IC50 32.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3cccc(F)c3)C3CCN(CC(F)F)CC3)C[C@H]2C1 CHEMBL1270693 IC50 35.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3cc(F)cc(F)c3)C3CN(S(=O)(=O)C4CC4)C3)C[C@H]2C1 CHEMBL1270401 IC50 35.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3cccc(F)c3)C3CCN(S(=O)(=O)c4ccccc4)CC3)C[C@H]2C1 CHEMBL1269385 IC50 38.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3cccc(F)c3)C3CN(S(=O)(=O)C4CC4)C3)C[C@H]2C1 CHEMBL1270303 IC50 39.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CN(S(=O)(=O)C4CC4)C3)C[C@H]2C1 CHEMBL1270209 IC50 40.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(=O)(=O)C(C)C)CC3)C[C@H]2C1 CHEMBL1271000 IC50 47.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(=O)(=O)CC(F)(F)F)CC3)C[C@H]2C1 CHEMBL1269383 IC50 48.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CN(S(C)(=O)=O)C3)C[C@H]2C1 CHEMBL1270494 IC50 52.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(C(=O)CC(C)C)CC3)C[C@H]2C1 CHEMBL1271310 IC50 68.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(C(=O)C(C)C)CC3)C[C@H]2C1 CHEMBL1271207 IC50 72.0 nM
COC(=O)N1CCC(C(CCN2C[C@@H]3CN(C(=O)c4c(C)ncnc4C)C[C@@H]3C2)c2ccccc2)CC1 CHEMBL1270900 IC50 102.0 nM
Cc1cccc(Cl)c1S(=O)(=O)C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CCN(S(C)(=O)=O)CC3)C[C@H]2C1 CHEMBL1269386 IC50 104.0 nM
Cc1ncnc(C)c1C(=O)N1C[C@H]2CN(CCC(c3ccccc3)C3CN(C(=O)C4CCCC4)C3)C[C@H]2C1 CHEMBL1269884 IC50 207.0 nM
CS(=O)(=O)N1CCC(C(CCN2C[C@@H]3CN(C(=O)S(=O)(=O)c4ccc(C#N)cc4Cl)C[C@@H]3C2)c2ccccc2)CC1 CHEMBL1269387 IC50 215.0 nM