COc1cc(/C=C/C(=O)N2C3CCC2CN(Cc2ccc(F)cc2)C3)c(NC(C)=O)cc1Cl CHEMBL372807 IC50 0.0 nM
Nc1nc2c(c(N3CCNCC3)n1)CCC1=C2[C@@H]2CCCC[C@@H]2O1 CHEMBL519240 Ki 0.043 nM
CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(C(=O)N[C@H]3C[C@H](C(=O)O)C3)nc2CC2CCCCC2)c2ccccc12 CHEMBL4128926 IC50 0.081 nM
CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)N1C[C@H](C)N(Cc2ccc(F)cc2)C[C@H]1C CHEMBL197375 IC50 0.1 nM
CCCCCCCCCCC(C)(C)C(=O)N[C@H]1CCCCNC1=O CHEMBL513863 ED50 0.15 nM
CC[C@H](NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1 CHEMBL4464625 IC50 0.2 nM
CCC(NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1 CHEMBL4457209 IC50 0.2 nM
CCCC(NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1 CHEMBL4475581 IC50 0.3 nM
CC(=O)Nc1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL2332935 IC50 0.36 nM
CC(=O)Nc1ccc(F)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(F)ccc1O2 CHEMBL2332933 IC50 0.36 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1NC(N)=O CHEMBL535607 IC50 0.4 nM
CC(C)NC(=O)N[C@@H](C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)C CHEMBL3656279 Ki 0.5 nM
CC(=O)Nc1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(F)ccc1O2 CHEMBL2332936 IC50 0.52 nM
O=C(Nc1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(F)ccc1O2)NC1CC1 CHEMBL3099947 IC50 0.63 nM
CC(=O)Nc1ccc(F)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL2332931 IC50 0.64 nM
C[C@H](NC(=O)N[C@@H]1CCCC[C@@H]1C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)(C)O CHEMBL3679659 IC50 0.7 nM
CC(C)[C@@H](NC(=O)C1CCCC1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398747 Ki 0.7 nM
CC[N+]1(C/C2=C/CCCCCC2)CCC(NC(=O)C2c3cc(Cl)ccc3Oc3ccc(Cl)cc32)CC1 CHEMBL277930 IC50 0.73 nM
CC(=O)Nc1ccc(O)cc1OC[C@@H](N)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL2332940 IC50 0.79 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)ccc1Cl CHEMBL2322875 IC50 0.8 nM
CC(C)[C@@H](NC(=O)[C@@H]1CC[C@H](O)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398729 IC50 0.8 nM
CC(C)[C@@H](NC(=O)[C@@H]1CC[C@@H](O)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398726 IC50 0.8 nM
CC(C)(O)c1ccc2c(c1)/C(=C\CCN1CC[C@](O)(c3ccc(Cl)cc3)C(C)(C)C1)c1cccnc1CO2 CHEMBL4571977 IC50 0.8 nM
O=C(Nc1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)NC1CC1 CHEMBL3099945 IC50 0.89 nM
CC[N+]1(C/C2=C/CCCCCC2)CCC(NC(=O)C2c3cc(Cl)ccc3Oc3ccc(Cl)cc32)CC1 CHEMBL331897 IC50 0.9 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)/C=C/c1ccc(Cl)cc1NC(N)=O CHEMBL196860 IC50 0.9 nM
COc1ccc(NC(C)=O)c(OC[C@@H](O)CN2CCC3(CC2)Cc2cc(Cl)ccc2O3)c1 CHEMBL2332930 IC50 0.9 nM
O=C(c1cc(Cl)c(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CC[C@H](O)C1 CHEMBL2391803 IC50 0.92 nM
CC(=O)Nc1ccccc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(F)ccc1O2 CHEMBL2332934 IC50 0.96 nM
CC(=O)Nc1ccccc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL2332932 IC50 0.96 nM
CC(C)(F)CCC(C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(=O)NN CHEMBL66159 IC50 1.0 nM
CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)N1CCN(Cc2ccc(F)cc2)C[C@H]1C CHEMBL198949 IC50 1.0 nM
CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)N1C[C@@H](C)N(Cc2ccc(F)cc2)C[C@@H]1C CHEMBL197345 IC50 1.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1NC(N)=O CHEMBL232656 Kd 1.0 nM
CC(C)[C@@H](NC(=O)CC1CC1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398717 IC50 1.0 nM
CC(C)[C@@H](NC(=O)NCc1ccccc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334818 IC50 1.0 nM
CC(C)[C@@H](NC(=O)NCC(C)(C)O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334824 IC50 1.0 nM
CC1(C)CN(C(=O)[C@H]2CCC[C@H]2NC(=O)c2cccc(S(N)(=O)=O)c2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679651 IC50 1.0 nM
O=C(c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CCC(O)CC1 CHEMBL2391810 IC50 1.1 nM
CC(C)[C@@H](NC(=O)[C@H]1CC[C@@H](O)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398728 IC50 1.1 nM
CC(C)CCC(=O)N[C@@H](C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)C CHEMBL2398744 IC50 1.2 nM
CC(C)[C@@H](NC(=O)Cc1ccncc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398769 IC50 1.2 nM
CS(=O)(=O)c1cc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)cc(C(F)(F)F)c1 CHEMBL4518015 IC50 1.2 nM
CN(C)[C@@H]1CCN(C(=O)c2ccc(O)cc2OC[C@@H](O)CN2CCC3(CC2)Cc2cc(Cl)ccc2O3)C1 CHEMBL2391797 IC50 1.3 nM
CNC(=O)Nc1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL3099942 IC50 1.3 nM
CC1(C)CN(C(=O)[C@H]2CCC[C@H]2NC(=O)C2CCCC2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679655 IC50 1.3 nM
CC(=O)Nc1ccc(O)cc1OC[C@@H](N)CN1CCC2(CC1)Cc1cc(F)ccc1O2 CHEMBL2332941 IC50 1.4 nM
O=C(NC1CC1)c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL2391795 IC50 1.4 nM
O=C(NC1CC1)c1ccc(F)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL2391939 IC50 1.4 nM
O=C(Nc1ccccc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CCCC1 CHEMBL3099940 IC50 1.4 nM
CC(NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1 CHEMBL4562738 IC50 1.4 nM
COc1cc(/C=C/C(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)c(NC(C)=O)cc1Cl CHEMBL200629 IC50 1.5 nM
CC1(C)CN(C(=O)[C@H]2CCC[C@H]2NC(=O)[C@H]2CC[C@@H](O)C2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679653 IC50 1.5 nM
Cc1cc(C)c(C(=O)NC(C)(C)CC(=O)N2CC[C@](O)(c3ccc(Cl)cc3)C(C)(C)C2)cn1 CHEMBL4436541 IC50 1.5 nM
CC1(C)CN(C(=O)[C@H]2CCC[C@H]2NC(=O)c2cccc(C(=O)O)c2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679654 IC50 1.6 nM
CC(C)[C@@H](NC(=O)CCCc1ccccc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398739 IC50 1.7 nM
CC(C)(CC(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)NC(=O)C1CCCC1 CHEMBL4574123 IC50 1.7 nM
NCC1CCCN(C(=O)c2ccc3c(c2)C(C(=O)NC2CCN(C/C4=C/CCCCCCC4)CC2)c2ccccc2O3)C1 CHEMBL2178571 Ki 1.8 nM
O=C(c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CCCC1 CHEMBL2391808 IC50 1.8 nM
CNC(=O)c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL2391793 IC50 1.8 nM
CC(C)[C@@H](NC(=O)Cc1ccccc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398737 IC50 1.8 nM
CC(C)[C@@H](NC(=O)C1CCC1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398746 IC50 1.8 nM
COc1ccc(NC(=O)NC2CC2)c(OC[C@@H](O)CN2CCC3(CC2)Cc2cc(Cl)ccc2O3)c1 CHEMBL3099944 IC50 1.8 nM
O=C(Nc1cc(Cl)c(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)NC1CC1 CHEMBL3099943 IC50 1.8 nM
CC1(C)CN(C(=O)[C@H]2CCC[C@H]2NC(=O)c2cccc(C(N)=O)c2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679656 IC50 1.8 nM
CS(=O)(=O)c1cc(C2(NC(=O)c3cncc4c3cnn4-c3ccc(F)cc3)CC2)ccn1 CHEMBL4456123 IC50 1.8 nM
CC(C)(CC(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)NC(=O)c1cccc(C(N)=O)c1 CHEMBL4476397 IC50 1.8 nM
CC[N+]1(C/C2=C/CCCCCC2)CCC(NC(=O)C2c3cc(Br)ccc3Oc3ccc(Br)cc32)CC1 CHEMBL289902 IC50 1.9 nM
O=C(c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CC[C@H](O)C1 CHEMBL2391804 IC50 1.9 nM
CC(C)CC(=O)N[C@@H](C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)C CHEMBL2398743 IC50 1.9 nM
C[C@H](NC(=O)NC(C)(C)CC(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)(C)O CHEMBL4466344 IC50 1.9 nM
CC(C)CC[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(N)=O CHEMBL304358 IC50 2.0 nM
CC[N+]1(C/C2=C/CCCCCC2)CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1 CHEMBL34732 IC50 2.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)[C@@H](C)C2)ccc1Cl CHEMBL2322853 IC50 2.0 nM
CC(C)[C@@H](NC(=O)NC1CCCC1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334725 IC50 2.0 nM
CC(C)[C@@H](NC(=O)N[C@@H]1CC[C@H](O)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334728 IC50 2.0 nM
CC[C@H](C)NC(=O)N[C@@H](C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)C CHEMBL3334817 IC50 2.0 nM
CC(C)[C@@H](NC(=O)NC[C@H](C)O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334821 IC50 2.0 nM
CC(C)[C@@H](NC(=O)C[C@@H](C)O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334822 IC50 2.0 nM
CC(C)[C@@H](NC(=O)NC[C@@H](C)O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334823 IC50 2.0 nM
CC(C)[C@@H](NC(=O)CCC(C)(C)O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334825 IC50 2.0 nM
CS(=O)(=O)c1cc(C2(NC(=O)c3cncc4c3cnn4-c3ccc(F)cc3)CCC2)ccn1 CHEMBL4474606 IC50 2.0 nM
CNS(=O)(=O)c1ccc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)cc1 CHEMBL4475173 IC50 2.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(-c4ncc[nH]4)c4cccnc43)CC2)ccc1Cl CHEMBL4444976 IC50 2.0 nM
CC[N+]1(C/C2=C/CCCCCC2)CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1 CHEMBL1178613 IC50 2.0 nM
CC1(C)CN(C(=O)[C@H]2CCCC[C@H]2NC(=O)c2ccccc2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679637 IC50 2.1 nM
CC[C@@H](C)NC(=O)N[C@@H](C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)C CHEMBL3334816 Ki 2.1 nM
CC(C)[C@@H](NC(=O)[C@@H]1CCC[C@@H]1N)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398724 IC50 2.2 nM
CC(C)[C@@H](NC(=O)C1CCCCC1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398748 IC50 2.2 nM
COc1ccc(NC(=O)NC2CC2)c(OC[C@@H](O)CN2CCC3(CC2)Cc2cc(F)ccc2O3)c1 CHEMBL3099946 IC50 2.2 nM
CC(C)(CC(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)NC(=O)c1cccc(-n2cnnn2)c1 CHEMBL4473668 IC50 2.2 nM
CC1(C)CN(CC/C=C2/c3cc(C(=O)O)ccc3OCc3ncccc32)C[C@H](c2ccc(Cl)cc2)[C@H]1O CHEMBL2178569 Ki 2.3 nM
CC(C)[C@@H](NC(=O)[C@@H]1CCC[C@@H]1O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398722 IC50 2.3 nM
CC(C)[C@@H](NC(=O)C1CCCC1(O)CCN1CCOCC1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398750 IC50 2.3 nM
CC(=O)Nc1cc(Cl)ccc1NCC(=O)N1CCN(Cc2ccc(F)cc2)C[C@H]1C CHEMBL370162 IC50 2.4 nM
C[N+]1(C/C2=C/CCCCCC2)CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1 CHEMBL32257 IC50 2.5 nM
O=C(c1ccc(F)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CC[C@H](O)C1 CHEMBL2391800 IC50 2.5 nM
COc1ccc(C(=O)NC2CC2)c(OC[C@@H](O)CN2CCC3(CC2)Cc2cc(Cl)ccc2O3)c1 CHEMBL2391938 IC50 2.5 nM
CC(C)[C@@H](NC(=O)CC12CC3CC(CC(C3)C1)C2)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398749 IC50 2.6 nM
CCC[N+]1(C/C2=C/CCCCCC2)CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1 CHEMBL33050 IC50 2.8 nM
O=C(NC1CC1)c1ccccc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL2391937 IC50 2.8 nM
Cc1nnc([C@H]2CCCN2C(=O)Nc2ccc(C(F)(F)F)cc2)n1Cc1ccc(Cl)cc1 CHEMBL1224189 IC50 2.9 nM
CC(C)[C@@H](NC(=O)c1ccc(F)c(O)c1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398763 IC50 2.9 nM
CC(C)[C@@H](NC(=O)C1CC1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398745 IC50 3.0 nM
CC(C)[C@@H](NC(=O)c1cccc(S(N)(=O)=O)c1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398767 IC50 3.0 nM
CC(C)[C@@H](NC(=O)N[C@H]1CC[C@H](O)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334727 IC50 3.0 nM
CC(C)[C@@H](NC(=O)N[C@H]1CC[C@@H](O)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334815 IC50 3.0 nM
CC(C)[C@@H](NC(=O)CC(C)(C)O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398716 IC50 3.0 nM
O=C(NCc1cccc(C(F)(F)F)c1)c1cncc2c1cnn2-c1ccc(F)cc1 CHEMBL4448761 IC50 3.0 nM
CCOc1cc(N2C3COCC2CN(C(=O)[C@H]2C[C@H](O)CN2c2ccc(Cl)cc2)C3)ccc1Cl CHEMBL4638406 IC50 3.0 nM
CCC[N+]1(CC2CCCCCCC2)CCC(NC(=O)C2c3cc(Br)ccc3Oc3ccc(Br)cc32)CC1 CHEMBL418589 IC50 3.1 nM
CNC(=O)c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(F)ccc1O2 CHEMBL2391794 IC50 3.2 nM
NC(=O)Nc1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL3099948 IC50 3.2 nM
CNC(=O)Nc1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(F)ccc1O2 CHEMBL3099961 IC50 3.2 nM
CC[N+]1(CC2CCCCCCC2)CCC(NC(=O)C2c3cc(Br)ccc3Oc3ccc(Br)cc32)CC1 CHEMBL33340 IC50 3.3 nM
CC(C)[C@@H](NC(=O)c1ccc(Cl)cc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398730 IC50 3.3 nM
CC(C)[C@@H](NC(=O)c1cccc(-c2ccccc2NC(N)=O)c1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398765 IC50 3.4 nM
COc1cc(N2CCC(C(Cn3nc(C(F)(F)F)c(Cl)c3C)NC(=O)[C@@H](C)O)CC2)c(Cl)cc1Cl CHEMBL4583778 Ki 3.46 nM
CCC[N+]1(CC2CCCCCCC2)CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1 CHEMBL33614 IC50 3.6 nM
CCC(=O)N[C@@H](C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)C CHEMBL2398741 IC50 3.6 nM
CC(C)[C@@H](NC(=O)c1cccnc1)C(=O)N1CC[C@H](c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398757 IC50 3.7 nM
C[N+]1(CC2CCCCCCC2)CCC(NC(=O)C2c3cc(Br)ccc3Oc3ccc(Br)cc32)CC1 CHEMBL33223 IC50 3.9 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1Nc1c(N)c(=O)c1=O CHEMBL232441 IC50 4.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N1CCC[C@@H]1c1nncn1Cc1ccc(Cl)cc1 CHEMBL1224188 IC50 4.0 nM
CC(C)[C@@H](NC(=O)N[C@@H]1CC[C@@H](O)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334726 IC50 4.0 nM
CC(C)[C@@H](NC(=O)C1CCCC1)C(=O)N1CCN(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398758 IC50 4.1 nM
CC(C)[C@@H](NC(=O)c1cccnc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398735 IC50 4.3 nM
COc1cc(N2CCC(C(Cn3nc(C(F)(F)F)c(Cl)c3C)NC(=O)CF)CC2)c(Cl)cc1Cl CHEMBL4565880 Ki 4.3 nM
CC(C)C(=O)N[C@@H](C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)C CHEMBL2398742 IC50 4.4 nM
CNC(=O)Nc1ccc(OC)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL3099941 IC50 4.5 nM
CNS(=O)(=O)c1ccc(CNC(=O)c2cccc3c2cnn3-c2ccc(F)cc2)cc1 CHEMBL4475237 IC50 4.5 nM
CC(C)[C@@H](NC(=O)c1ccccc1Cl)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398770 IC50 4.7 nM
NC(=O)C(C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C1CCCCC1 CHEMBL68145 IC50 5.0 nM
CCCC[N+]1(CC2CCCCCCC2)CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1 CHEMBL32713 IC50 5.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1Nc1c(NCCN2CCNCC2)c(=O)c1=O CHEMBL387608 IC50 5.0 nM
Cc1nnc(C(=O)NC(C)(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2C)o1 CHEMBL254316 Ki 5.0 nM
CO[C@@H]1COCC[C@@H]1NC1CC[C@@](C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)(C(C)C)C1 CHEMBL2178572 IC50 5.0 nM
CC(=O)Nc1ccc(O)cc1OC[C@@](C)(O)CNC1CCN(Cc2ccc(Cl)cc2)CC1 CHEMBL2178570 Ki 5.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(F)c3C)CC2)ccc1Cl CHEMBL2322858 IC50 5.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)cc(F)c1Cl CHEMBL2322879 IC50 5.0 nM
Cc1ccc(C(=O)N2CC[C@H](O)C2)c(OC[C@@H](O)CN2CCC3(CC2)Cc2cc(Cl)ccc2O3)c1 CHEMBL2391799 IC50 5.0 nM
CC(C)NS(=O)(=O)c1ccc(CNC(=O)c2cccc3c2cnn3-c2ccc(F)cc2)cc1 CHEMBL4465000 IC50 5.0 nM
O=C(C1=C(O)C(=O)N(c2ccc(Br)cc2F)C1C1CCCCC1)C1CC1 CHEMBL4450561 Ki 5.0 nM
COc1cc(N2CCC(C(Cn3nc(C(F)(F)F)c(Cl)c3C)NC(=O)CO)CC2)c(Cl)cc1Cl CHEMBL4452884 Ki 5.15 nM
CC[N+]1(CC2CCCCCCC2)CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1 CHEMBL280751 IC50 5.2 nM
NC(=O)Nc1ccc(F)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL3099950 IC50 5.6 nM
CC(C)[C@@H](NC(=O)CCc1ccccc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398738 IC50 5.8 nM
C[N+]1(CCCC(c2ccccc2)c2ccccc2)CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL356099 Ki 6.0 nM
CC(=O)Nc1cc2ncccc2cc1/C=C/C(=O)N1C2CCC1CN(Cc1ccc(F)cc1)C2 CHEMBL200680 IC50 6.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)/C=C/c1ccc(Cl)cc1Nc1c(N)c(=O)c1=O CHEMBL389293 IC50 6.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1Nc1c(NCCN)c(=O)c1=O CHEMBL232837 IC50 6.0 nM
Cc1cc(C(F)(F)F)cc(C)c1NC(=O)N1CCC[C@@H]1C(=O)N(C)Cc1ccc(Cl)cc1 CHEMBL475748 IC50 6.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(C#N)c3C)CC2)ccc1Cl CHEMBL2322861 IC50 6.0 nM
COc1ccc(NC(C)=O)c(OC[C@@H](N)CN2CCC3(CC2)Cc2cc(Cl)ccc2O3)c1 CHEMBL2332937 IC50 6.0 nM
CN(C)S(=O)(=O)c1ccc(CNC(=O)c2cccc3c2cnn3-c2ccc(F)cc2)cc1 CHEMBL4475918 IC50 6.0 nM
CC(C)[C@@H](NC(=O)[C@H]1CC[C@H](O)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398727 IC50 6.3 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N1CCC[C@@H]1c1nnnn1Cc1ccc(Cl)cc1 CHEMBL1224119 IC50 6.5 nM
NC(=O)Nc1ccccc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL3099949 IC50 6.7 nM
CC(C)[C@@H](NC(=O)c1cccc(-c2ccccc2NC(N)=O)c1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2398764 IC50 6.8 nM
CS(=O)(=O)c1cc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1 CHEMBL4441094 IC50 6.8 nM
COc1cc(N2CCC(C(Cn3nc(C(F)(F)F)c(Cl)c3C)NC(C)=O)CC2)c(Cl)cc1Cl CHEMBL4448154 Ki 6.8 nM
O=C(N[C@@H](Cc1ccccc1)[C@@H](O)CC(C(=O)NO)C1CCC(F)(F)CC1)c1cnc2ccccc2n1 CHEMBL303673 IC50 7.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(I)c3C)CC2)ccc1Cl CHEMBL2322860 IC50 7.0 nM
O=C(c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CCCCC1 CHEMBL2391809 IC50 7.1 nM
CC(C)[C@@H](NC(=O)c1cccc(C(=O)O)c1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398733 IC50 7.1 nM
O=C1COc2cccc(OC[C@@H](O)CN3CCC4(CC3)Cc3cc(Cl)ccc3O4)c2N1 CHEMBL3099951 IC50 7.1 nM
CC(C)[C@@H](NC(=O)c1cccnc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C2(CC2)C1 CHEMBL2398718 IC50 7.2 nM
CC(C)[C@@H](NC(=O)c1ccncc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398736 IC50 7.6 nM
CO[C@H]1CCN(C(=O)c2ccc(O)cc2OC[C@@H](O)CN2CCC3(CC2)Cc2cc(Cl)ccc2O3)C1 CHEMBL2391806 IC50 7.9 nM
O=C(c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CC[C@@H](O)C1 CHEMBL2391796 IC50 7.9 nM
C[N+]1(CCCC(C#N)(c2ccccc2)c2ccccc2)CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL141127 Ki 8.0 nM
NC(=O)[C@@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C1CCCCC1 CHEMBL69375 IC50 8.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1Nc1c(NCc2cccnc2)c(=O)c1=O CHEMBL397910 IC50 8.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)COc1ccc(Cl)cc1NC(=O)NCCN CHEMBL391238 IC50 8.0 nM
CC(C)[C@@H](NC(=O)CC1CCCCC1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180505 IC50 8.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(C)C)c(Cl)c3C)CC2)ccc1Cl CHEMBL2322844 IC50 8.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Br)c3C)CC2)ccc1Cl CHEMBL2322859 IC50 8.0 nM
CS(=O)(=O)c1cccc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)c1 CHEMBL4475801 IC50 8.0 nM
Cc1ccc(C(=O)N2CC[C@H](O)C2)c(OC[C@@H](O)CN2CCC3(CC2)Cc2cc(F)ccc2O3)c1 CHEMBL2391798 IC50 8.9 nM
CC(C)(F)CC[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(N)=O CHEMBL68366 IC50 9.0 nM
O=C(NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1)NC1CCNCC1 CHEMBL142752 Ki 9.0 nM
CN(C)CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)N1C2CCC1CN(Cc1ccc(F)cc1)C2 CHEMBL200242 IC50 9.0 nM
COc1ccc(NC(C)=O)c(OC[C@@H](N)CN2CCC3(CC2)Cc2cc(F)ccc2O3)c1 CHEMBL2332938 IC50 9.0 nM
CC(C)[C@@H](NC(=O)N1CCCC1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334819 IC50 9.0 nM
CC(C)[C@@H](NC(=O)Cc1ccncc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2398768 IC50 9.4 nM
CC(=O)Nc1cc(Cl)cc2cc(C(=O)N3CCN(Cc4ccc(F)cc4)C[C@H]3C)[nH]c12 CHEMBL200794 IC50 9.6 nM
CC[N+]1(CC2CCCCCC2)CCC(NC(=O)C2c3cc(Cl)ccc3Oc3ccc(Cl)cc32)CC1 CHEMBL486030 IC50 9.6 nM
C=CC[N+]1(CC2CCCCCCC2)CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1 CHEMBL33104 IC50 9.7 nM
CC(C)[C@@H](NC(=O)c1cccc(Cl)c1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398771 IC50 9.9 nM
COc1cc(N2CCN(C(=O)Cn3nc(S(C)(=O)=O)c(Cl)c3C)CC2)ccc1Cl CHEMBL2321887 IC50 10.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C#N)c(Cl)c3C)CC2)ccc1Cl CHEMBL2322847 IC50 10.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3CO)CC2)ccc1Cl CHEMBL2322867 IC50 10.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)cc(Cl)c1Cl CHEMBL2322880 IC50 10.0 nM
CC(C)[C@@H](NC(=O)c1ccccc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398761 IC50 10.0 nM
CC(C)[C@@H](NC(=O)c1ccc(F)c(O)c1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2398762 IC50 10.0 nM
CCC[C@H](NC(=O)c1cnn(-c2ccc(Cl)cc2)c1C)c1cccc(C(F)(F)F)c1F CHEMBL4436061 IC50 10.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2F)C1C1CCCCC1 CHEMBL4577133 pKi 10.47 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)[C@H](CO)C2)ccc1Cl CHEMBL2322854 IC50 11.0 nM
CC(C)[C@@H](NC(=O)C[C@H](C)O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334820 IC50 11.0 nM
[C-]#[N+]c1ccc([C@@]2(O)CCN(C(=O)[C@H]3CCCC[C@H]3NC(=O)c3cccc(C(=O)O)c3)CC2(C)C)cc1 CHEMBL3679657 IC50 11.3 nM
CC1(C)CN(C(=O)[C@H]2CCCC[C@H]2NC(=O)c2cccc(C(=O)O)c2)CC[C@]1(O)c1ccc(C#N)cc1 CHEMBL4443024 IC50 11.3 nM
CC1(C)CN(C(=O)[C@H]2CCC[C@H]2NC(=O)Nc2ccccc2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679639 IC50 11.5 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1Nc1c(NCCN2CCOCC2)c(=O)c1=O CHEMBL234295 IC50 12.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)cc(CO)c1Cl CHEMBL2322886 IC50 12.0 nM
CCOc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)ccc1Cl CHEMBL2322876 IC50 12.0 nM
O=C(c1ccc(F)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(F)ccc1O2)N1CC[C@H](O)C1 CHEMBL2391802 IC50 12.0 nM
O=C(NCCO)c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL2391812 IC50 12.0 nM
CN1CCN(S(=O)(=O)c2ccc(CNC(=O)c3cccc4c3cnn4-c3ccc(F)cc3)cc2)CC1 CHEMBL4586189 IC50 12.0 nM
CC(C)(NC(=O)c1cncc2c1cnn2-c1ccc(F)cc1)c1ccnc(S(C)(=O)=O)c1 CHEMBL4464575 IC50 12.0 nM
CS(=O)(=O)c1ccc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)cc1 CHEMBL4442765 IC50 12.0 nM
CC(C)(C)OC(=O)N[C@@H]1CCC[C@@H]1C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3679638 IC50 12.1 nM
CC(=O)Nc1cc2ccccc2cc1/C=C/C(=O)N1CCN(Cc2ccc(F)cc2)C[C@H]1C CHEMBL370596 IC50 13.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1Nc1c(NCCO)c(=O)c1=O CHEMBL232638 IC50 13.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)COc1ccc(Cl)cc1C(=O)CCC(=O)O CHEMBL234263 IC50 13.0 nM
CC(C)[C@@H](NC(=O)Cc1ccccc1F)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180186 IC50 13.0 nM
CC(=O)N[C@@H](C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)C CHEMBL2398740 IC50 13.0 nM
CNC(=O)Nc1ccc(OC)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(F)ccc1O2 CHEMBL3099960 IC50 13.0 nM
CC[C@H](NC(=O)c1cnn(-c2ccc(Cl)cc2)c1C)c1cccc(C(F)(F)F)c1F CHEMBL4577357 IC50 13.0 nM
C[N+]1(CC2CCCCCCC2)CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1 CHEMBL34165 IC50 14.0 nM
CNc1c(Nc2cc(Br)ccc2OCC(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)c(=O)c1=O CHEMBL232253 IC50 14.0 nM
CC(C)[C@@H](NC(=O)c1ccc(F)c(F)c1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180508 IC50 14.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)cc(Br)c1Cl CHEMBL2322881 IC50 14.0 nM
CC1(C)CN(C(=O)[C@H]2CCC[C@H]2NC(=O)[C@@H]2CC[C@H](O)C2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679652 IC50 14.0 nM
C[N+]1(CC2CCCCCCC2)CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1 CHEMBL1178601 IC50 14.0 nM
C[C@@H](O)CNC(=O)N[C@@H]1CCCC[C@@H]1C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3679650 IC50 14.6 nM
CC1CC([C@H](C[C@H](O)[C@H](Cc2ccccc2)NC(=O)c2cnc3ccccc3n2)C(N)=O)CC(C)O1 CHEMBL69659 IC50 15.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1Nc1c(NCc2ccccn2)c(=O)c1=O CHEMBL428193 IC50 15.0 nM
CC(C)[C@@H](NC(=O)c1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180528 IC50 15.0 nM
CC(C)[C@@H](NC(=O)c1ccccn1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398734 IC50 15.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(Cl)cc2F)C1C1CCCCC1 CHEMBL4475389 Ki 15.0 nM
CCCC(NC(=O)c1cnn(-c2ccc(Cl)cc2)c1C)c1cncc(S(C)(=O)=O)c1 CHEMBL4568048 IC50 15.0 nM
CC1(C)CN(C(=O)[C@H]2CCCC[C@H]2NC(=O)CCc2ccccc2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679646 IC50 15.7 nM
O=C(Nc1ccccc1OCC(O)CN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1)C1CCC1 CHEMBL2208416 pKi 15.85 nM
Cc1cc(C(F)(F)F)ccc1NC(=O)N1CCC[C@@H]1C(=O)N(C)Cc1ccc(Cl)cc1 CHEMBL473734 IC50 16.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N1CCCC1c1nccn1Cc1ccc(Cl)cc1 CHEMBL1224118 IC50 16.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(C)(C)O)c(Cl)c3C)CC2)ccc1Cl CHEMBL2322845 IC50 16.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)cc(CN)c1Cl CHEMBL2322887 IC50 16.0 nM
C[N+]1(CC2CCCCCCC2)CCC(NC(=O)C2c3cc(Cl)ccc3Oc3ccc(Cl)cc32)CC1 CHEMBL33929 IC50 17.0 nM
CNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)c(=O)c1=O CHEMBL231829 IC50 17.0 nM
CC(C)[C@@H](NC(=O)[C@@H]1CCC[C@H]1N)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398725 IC50 17.0 nM
O=C(NCc1cccc(C(F)(F)F)c1)c1cccc2c1cnn2-c1ccc(F)nc1 CHEMBL4449996 IC50 17.0 nM
CC1(C)CN(C(=O)[C@H]2CC(=O)CC[C@H]2NC(=O)c2ccccc2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679641 IC50 17.2 nM
CC(C)[C@@H](NC(=O)c1nc2ccccc2s1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180195 IC50 18.0 nM
CC(C)[C@@H](NC(=O)CCc1ccccc1F)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180192 IC50 18.0 nM
COc1cc(N2CCN(C(=O)Cn3cc(Cl)c(C(F)(F)F)n3)CC2)ccc1Cl CHEMBL2322863 IC50 18.0 nM
CC(=O)Nc1ccc(O)cc1OC[C@@H](N)CN1CCC2(CC1)Cc1ccccc1O2 CHEMBL2332942 IC50 18.0 nM
Cc1ccc(N2C(=O)C(O)=C(C(=O)C3CC3)C2C2CCCCC2)cc1 CHEMBL4471583 pKi 18.2 nM
CC1(C)CN(C(=O)[C@H]2CCCC[C@H]2NC(=O)Nc2ccccc2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679642 IC50 18.5 nM
CC1(C)CN(C(=O)[C@H]2CCCC[C@H]2NC(=O)c2cncnc2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679644 IC50 18.7 nM
COCCNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)c(=O)c1=O CHEMBL387822 IC50 19.0 nM
Cc1ccccc1CCC(=O)N[C@@H](C(=O)N1CCC(c2ccc(Cl)cc2)CC1)C(C)C CHEMBL2180190 IC50 19.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)cc3C)CC2)ccc1Cl CHEMBL2322857 IC50 19.0 nM
CCS(=O)(=O)c1cc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)ccn1 CHEMBL4466500 IC50 19.0 nM
NC(=O)C(C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C1CCC(F)(F)CC1 CHEMBL302533 IC50 20.0 nM
CC(=O)Nc1cc2ncccc2cc1/C=C/C(=O)N1CCN(Cc2ccc(F)cc2)C[C@H]1C CHEMBL199412 IC50 20.0 nM
CC(C)[C@@H](NC(=O)CC1CCCC1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180504 IC50 20.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(Br)c(Cl)c3C)CC2)ccc1Cl CHEMBL2322846 IC50 20.0 nM
CC(C)[C@@H](NC(=O)[C@@H]1CCC[C@H]1O)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398723 IC50 20.0 nM
CC(C)[C@@H](NC(=O)Nc1ccccc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3334724 IC50 20.0 nM
Cc1ccc(N2C(=O)C(O)=C(C(=O)C(C)(C)C)C2C2CCCCC2)cc1 CHEMBL4569870 pKi 21.88 nM
N#CC1(CCCN2CCC(O)(c3ccc(Br)cc3)CC2)c2ccccc2CSc2ccccc21 CHEMBL143350 Ki 22.0 nM
C[N+]1(CCCC(C#N)c2ccc3ccccc3c2)CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL143374 Ki 22.0 nM
CNC(=O)[C@H](CCC(C)C)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1 CHEMBL304845 IC50 22.0 nM
CN(Cc1ccc(Cl)cc1)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(C(F)(F)F)cc1 CHEMBL514611 IC50 22.0 nM
CN(Cc1ccc(Cl)cc1)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(C(F)(F)F)cc1F CHEMBL473532 IC50 22.0 nM
O=C(Nc1ccc(C(F)(F)F)cc1)N1CCC[C@@H]1c1ncnn1Cc1ccc(Cl)cc1 CHEMBL1224120 IC50 22.0 nM
Cc1cccc(CCC(=O)N[C@@H](C(=O)N2CCC(c3ccc(Cl)cc3)CC2)C(C)C)c1 CHEMBL2180191 IC50 22.0 nM
O=C(NCc1cccc(C(F)(F)F)c1)c1cccc2c1cnn2-c1ccc(F)cc1 CHEMBL4448064 IC50 22.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)COc1ccc(Cl)cc1CS(=O)(=O)O CHEMBL430166 IC50 23.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)C[C@@H]2C)ccc1Cl CHEMBL2322856 IC50 23.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1C1CCCCC1 CHEMBL4457687 pKi 23.99 nM
N#CC1(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2CSc2ccccc21 CHEMBL143492 Ki 24.0 nM
CC(C)[C@@H](NC(=O)c1cccc(F)c1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180506 IC50 24.0 nM
Cc1ccc(C(=O)N[C@@H](C(=O)N2CCC(c3ccc(Cl)cc3)CC2)C(C)C)cc1 CHEMBL2180510 IC50 25.0 nM
NC(=O)[C@@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C1CCCC1 CHEMBL69274 IC50 26.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1Nc1c(NCc2ccncc2)c(=O)c1=O CHEMBL232654 IC50 26.0 nM
CC(C)CCC(=O)N[C@@H](C(=O)N1CCC(c2ccc(Cl)cc2)CC1)C(C)C CHEMBL2180502 IC50 26.0 nM
CC(C)(F)CCC(C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(=O)NO CHEMBL305423 IC50 27.0 nM
O=C(C1=C(O)C(=O)N(c2ccc(Br)cc2F)C1C1CCCCC1)c1ccccc1 CHEMBL4561618 pKi 27.54 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2F)C1C1CCCCC1 CHEMBL4519533 pKi 27.54 nM
CC(=O)Nc1cc(Cl)cc2cc(C(=O)N3CCN(Cc4ccc(F)cc4)C[C@H]3C)oc12 CHEMBL198966 IC50 28.0 nM
Cc1c(C(=O)N[C@@H](C)c2cccc(C(F)(F)F)c2F)cnn1-c1ccc(Cl)cc1 CHEMBL4513370 IC50 28.0 nM
CCCC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1C1CCCCC1 CHEMBL4461627 pKi 28.84 nM
N#CC1(CCCN2CCC(O)(c3ccc(Br)cc3)CC2)c2ccccc2Cc2ccccc21 CHEMBL435485 Ki 29.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)COc1ccc(Cl)cc1C(=O)NCCN CHEMBL391302 IC50 30.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1c(Cl)cccc1Cl CHEMBL255629 IC50 30.0 nM
Cc1ccccc1S(=O)(=O)NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL256404 IC50 30.0 nM
CC(C)[C@@H](NC(=O)Cc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180496 IC50 30.0 nM
CCC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1C1CCCCC1 CHEMBL4513770 Ki 30.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(Cl)c(C)c2)C1C1CCCCC1 CHEMBL4535696 pKi 30.9 nM
O=C(NCCCO)NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL124127 IC50 31.0 nM
CCCCC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1C1CCCCC1 CHEMBL4530510 Ki 31.0 nM
CN1C(=O)c2ccccc2C(C#N)(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc21 CHEMBL142925 Ki 32.0 nM
Cc1ccccc1C(=O)N[C@@H](C(=O)N1CCC(c2ccc(Cl)cc2)CC1)C(C)C CHEMBL2180509 IC50 32.0 nM
CC(C)CC(=O)N[C@@H](C(=O)N1CCC(c2ccc(Cl)cc2)CC1)C(C)C CHEMBL2180525 IC50 32.0 nM
COc1ccc(NC(C)=O)c(OC[C@@H](N)CN2CCC3(CC2)Cc2ccccc2O3)c1 CHEMBL2332939 IC50 32.0 nM
O=C(c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CCOCC1 CHEMBL2391811 IC50 32.0 nM
O=C1CCc2cccc(OC[C@@H](O)CN3CCC4(CC3)Cc3cc(Cl)ccc3O4)c2N1 CHEMBL3099952 IC50 32.0 nM
CCOC(=O)C(C#N)(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL344324 Ki 33.0 nM
N#CC1(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2COc2ccccc21 CHEMBL343511 Ki 34.0 nM
CC[C@@H](C)[C@@H](NC(=O)CC(C)C)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180526 IC50 34.0 nM
CS(=O)(=O)c1ccc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)cn1 CHEMBL4454067 IC50 34.0 nM
CN(Cc1ccc(Cl)cc1)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(C(F)(F)F)cc1Cl CHEMBL473531 IC50 35.0 nM
CC(C)C(NC(=O)CCc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180515 IC50 35.0 nM
Cc1ccccc1C(=O)NC(C(=O)N1CCC(c2ccc(Cl)cc2)CC1)C(C)C CHEMBL2180542 IC50 36.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)[C@H](C)C2)ccc1Cl CHEMBL2322852 IC50 37.0 nM
O=c1ccc2cccc(OC[C@@H](O)CN3CCC4(CC3)Cc3cc(Cl)ccc3O4)c2[nH]1 CHEMBL3099953 IC50 37.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)COc1ccc(Cl)cc1CC(=O)O CHEMBL234262 IC50 38.0 nM
CC[C@@H](C)[C@@H](NC(=O)Cc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180497 IC50 38.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(Cl)cc2)C1C1CCCCC1 CHEMBL4443909 pKi 38.9 nM
CC(C)(O)CC[C@H](C[C@H](O)[C@H](Cc1cccc(F)c1)NC(=O)c1cnc2ccccc2n1)C(N)=O CHEMBL1628706 IC50 39.0 nM
Cc1cccc(Cl)c1S(=O)(=O)NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL429419 IC50 40.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1Cl CHEMBL269957 IC50 40.0 nM
CC(C)[C@@H](NC(=O)CCc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180499 IC50 40.0 nM
CC(C)C(NC(=O)Cc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180514 IC50 40.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C)c(Cl)c3C)CC2)ccc1Cl CHEMBL2322843 IC50 40.0 nM
CC(C)[C@@H](NC(=O)c1cccc(S(N)(=O)=O)c1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2398766 IC50 40.0 nM
Cc1ccc(N2C(=O)C(O)=C(C(=O)C(C)C)C2C2CCCCC2)cc1 CHEMBL4439354 pKi 40.74 nM
O=C(NCc1ccnc(S(=O)(=O)C2CC2)c1)c1cncc2c1cnn2-c1ccc(F)cc1 CHEMBL4472994 IC50 41.0 nM
CC1(C)CN(C(=O)CCNC(=O)c2ccccc2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL4444092 IC50 41.6 nM
CC(CNC(=O)C1CCCC1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL4443458 IC50 42.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)c(C)c2)C1C1CCCCC1 CHEMBL4464639 pKi 42.66 nM
CC(=O)N[C@@H]1CC[C@@H](C(=O)N[C@H](C)CC(=O)N2CC[C@](O)(c3ccc(Cl)cc3)C(C)(C)C2)C1 CHEMBL4546558 IC50 43.9 nM
N#CC1(CCCN2CCC(O)(c3ccc(F)cc3)CC2)c2ccccc2CSc2ccccc21 CHEMBL142318 Ki 44.0 nM
COS(=O)(=O)NC(=O)Cc1cc(Cl)ccc1OCC(=O)N1C[C@H](C)N(Cc2ccc(F)cc2)C[C@H]1C CHEMBL391239 IC50 44.0 nM
CC(C)[C@@H](NC(=O)Cc1cccc(F)c1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180187 IC50 44.0 nM
CN(C)S(=O)(=O)c1cccc(CNC(=O)c2cccc3c2cnn3-c2ccc(F)cc2)c1 CHEMBL4565496 IC50 44.0 nM
N#CC1(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2CCc2ccccc21 CHEMBL433746 Ki 45.0 nM
CC(C)[C@@H](NC(=O)Cc1cccc(Cl)c1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2177135 IC50 45.0 nM
CC[C@@H](C)[C@@H](NC(=O)c1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180493 IC50 45.0 nM
CC(C)(CC(=O)N1CCC(O)(c2ccc(C#N)cc2)C(C)(C)C1)NC(=O)c1ccccc1 CHEMBL4593102 IC50 45.3 nM
CC(C)(O)CCC(C[C@H](O)[C@H](Cc1cccc(F)c1)NC(=O)c1cnc2ccccc2n1)C(N)=O CHEMBL308473 IC50 46.0 nM
CC(C)[C@@H](NC(=O)CC1CC1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180503 IC50 46.0 nM
C[C@H](CC(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1)NC(=O)[C@@H]1CC[C@@H](NC(=O)OC(C)(C)C)C1 CHEMBL4592423 IC50 46.7 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3CN(C)C)CC2)ccc1Cl CHEMBL2322869 IC50 47.0 nM
CCCC(NC(=O)c1cnn(-c2ccc(Cl)cc2)c1C)c1ccc(S(C)(=O)=O)nc1 CHEMBL4583870 IC50 47.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)c(F)c2)C1C1CCCCC1 CHEMBL4529804 pKi 47.86 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL34166 IC50 48.0 nM
NC(=O)[C@H](CC1CCCC1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1 CHEMBL306685 IC50 48.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1C(F)(F)F CHEMBL258065 IC50 50.0 nM
CC[C@@H](NC(=O)Cc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180495 IC50 50.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3CN)CC2)ccc1Cl CHEMBL2322868 IC50 50.0 nM
O=C(C1=C(O)C(=O)N(c2ccc(Br)cc2F)C1c1cccc(Br)c1)C1CC1 CHEMBL4439854 Ki 50.0 nM
N#CC(CCCCl)(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL142191 Ki 51.0 nM
O=C(NC1CCN(C/C2=C/CCCCCC2)CC1)C1c2ccccc2Oc2ccccc21 CHEMBL33277 IC50 51.0 nM
CC(C)(O)CCC(C[C@H](O)[C@H](Cc1ccccc1F)NC(=O)c1cnc2ccccc2n1)C(N)=O CHEMBL304053 IC50 52.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)cc(C(N)=O)c1Cl CHEMBL2322883 IC50 52.0 nM
COC(=O)C(C#N)(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL343680 Ki 53.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL143059 Ki 54.0 nM
N#CC1(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2C[S+]([O-])c2ccccc21 CHEMBL143173 Ki 54.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1C1CCCCCC1 CHEMBL4459033 pKi 54.95 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1C1CCCCC1 CHEMBL4453024 pKi 54.95 nM
CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180534 IC50 55.0 nM
CNS(=O)(=O)c1cccc(CNC(=O)c2cccc3c2cnn3-c2ccc(F)cc2)c1 CHEMBL4437170 IC50 55.0 nM
N#CC1(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2C=Cc2ccccc21 CHEMBL344073 Ki 56.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1C1CCCCCCC1 CHEMBL4467708 Ki 57.0 nM
CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)N1CCN(Cc2ccc(F)cc2)CC1 CHEMBL198852 IC50 58.0 nM
CC(C)[C@@H](NC(=O)c1cc2ccccc2s1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180196 IC50 58.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)[C@@H](C)CN1C(=O)COc1ccc(Cl)cc1C(=O)O CHEMBL391301 IC50 59.0 nM
CS(=O)(=O)c1cccc(CNC(=O)c2cccc3c2cnn3-c2ccc(F)cc2)c1 CHEMBL4559388 IC50 61.0 nM
CS(=O)(=O)c1cncc(CNC(=O)c2cncc3c2cnn3-c2ccc(F)cc2)c1 CHEMBL4519965 IC50 61.0 nM
CNC(=O)[C@H](CC(C)C)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1 CHEMBL68581 IC50 64.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1Nc1c(NCCN2CCCC2)c(=O)c1=O CHEMBL233042 IC50 64.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2F)C1c1cccc(Br)c1 CHEMBL4458295 pKi 64.57 nM
CC[C@@H](C)[C@@H](NC(=O)CCc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180500 IC50 66.0 nM
CN(C)CCNC(=O)NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL340797 IC50 67.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1c1ccc(Cl)cc1 CHEMBL4452558 Ki 67.0 nM
NC(=O)C(C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C1(O)CCC(F)(F)CC1 CHEMBL302320 IC50 68.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3CNC(C)=O)CC2)ccc1Cl CHEMBL2322870 IC50 68.0 nM
CS(=O)(=O)c1ccc(CNC(=O)c2cccc3c2cnn3-c2ccc(F)cc2)cc1 CHEMBL4469176 IC50 68.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cccs1 CHEMBL272097 IC50 70.0 nM
CC(C)[C@@H](NC(=O)CCc1ccc(F)cc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180193 IC50 70.0 nM
CC(C)[C@@H](NC(=O)C1CCCC1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180501 IC50 70.0 nM
CC(C)(C)NC(=O)NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL435812 IC50 71.0 nM
CC(=O)NCCNC(=O)c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL2391935 IC50 71.0 nM
CCNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)c(=O)c1=O CHEMBL234073 IC50 72.0 nM
COc1ccc(C(C#N)CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)cc1Br CHEMBL142468 Ki 74.0 nM
CCNC(=O)C(CCC(C)(C)F)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1 CHEMBL69123 IC50 75.0 nM
CNc1c(Nc2cc(Cl)ccc2/C=C/C(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)c(=O)c1=O CHEMBL232655 IC50 76.0 nM
Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N1CCN(c2ccc(Cl)c(OC(C)C)c2)CC1 CHEMBL2322877 IC50 77.0 nM
Cc1ccc(N2C(=O)C(O)=C(C(=O)c3ccccc3)C2C2CCCCC2)cc1 CHEMBL4538013 Ki 77.0 nM
N#CC(CCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL142199 Ki 78.0 nM
CNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(Cl)cc3)C[C@H]2C)c(=O)c1=O CHEMBL390706 IC50 78.0 nM
N[C@H](COc1cccc2c1NC(=O)CO2)CN1CCC2(CC1)Cc1cc(F)ccc1O2 CHEMBL3099958 IC50 79.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1F CHEMBL256888 IC50 80.0 nM
CC(C)C(NC(=O)c1ccc2ccccc2c1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180513 IC50 80.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1-c1ccccc1 CHEMBL272523 IC50 84.0 nM
CC[C@@H](NC(=O)CCc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180498 IC50 85.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1c1ccc(Br)cc1 CHEMBL4453953 pKi 85.11 nM
Cc1ccccc1C(=O)NC(CC(C)C)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180543 IC50 88.0 nM
CC(=O)N[C@H]1CCN(C(=O)c2ccc(O)cc2OC[C@@H](O)CN2CCC3(CC2)Cc2cc(Cl)ccc2O3)C1 CHEMBL2391807 IC50 89.0 nM
CNc1c(Nc2cc(C)ccc2OCC(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)c(=O)c1=O CHEMBL430356 IC50 90.0 nM
O=S(=O)(c1ccccc1Br)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 CHEMBL403728 IC50 90.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL270631 IC50 90.0 nM
N#Cc1ccc(C2(O)CCN(CCCC(C#N)(c3ccccc3)c3ccccc3)CC2)cc1 CHEMBL143499 Ki 92.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)C[C@H]2C)ccc1Cl CHEMBL2322855 IC50 92.0 nM
CCC(C#N)(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL343028 Ki 93.0 nM
Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N1CCN(c2ccc(F)cc2)CC1 CHEMBL2322888 IC50 93.0 nM
CC(C)[C@@H](NC(=O)CCCc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180516 IC50 95.0 nM
CNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(F)c(F)c3)C[C@H]2C)c(=O)c1=O CHEMBL232043 IC50 97.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(CO)c(Cl)c3C)CC2)ccc1Cl CHEMBL2322849 IC50 97.0 nM
N#Cc1ccccc1C(C#N)CCCN1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL344989 Ki 98.0 nM
Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N1CCN(c2ccc(Cl)cc2)CC1 CHEMBL2322890 IC50 98.0 nM
N#CC(CCCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL142620 Ki 99.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1Cl CHEMBL257509 IC50 100.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cccc(Cl)c1 CHEMBL256821 IC50 100.0 nM
Cc1cccc(C(=O)N[C@@H](C(=O)N2CCC(c3ccc(Cl)cc3)CC2)C(C)C)c1C CHEMBL2180511 IC50 100.0 nM
Cc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)ccc1Cl CHEMBL2322874 IC50 100.0 nM
Cc1ccc(CCC(=O)N[C@@H](C(=O)N2CCC(c3ccc(Cl)cc3)CC2)C(C)C)cc1 CHEMBL2180194 IC50 105.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)cc(C)c1Cl CHEMBL2322878 IC50 107.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1-c1ccsc1 CHEMBL255338 IC50 110.0 nM
CN(C)[C@H]1CCN(C(=O)c2ccc(O)cc2OC[C@@H](O)CN2CCC3(CC2)Cc2cc(Cl)ccc2O3)C1 CHEMBL2391805 IC50 110.0 nM
COc1cc(N2CCC(C(O)Cn3ccc(C(F)(F)F)n3)CC2)ccc1Cl CHEMBL4590794 Ki 114.0 nM
CC(C)[C@@H](NC(=O)Cc1ccc(Cl)cc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180188 IC50 115.0 nM
OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1 CHEMBL142004 Ki 116.0 nM
CC(C)[C@@H](NC(=O)c1ccc(F)cc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180507 IC50 118.0 nM
NC(=O)C(C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C1(O)CCCCC1 CHEMBL306457 IC50 120.0 nM
CC1CC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CCN1S(=O)(=O)c1ccccc1Br CHEMBL256272 IC50 120.0 nM
Cc1ccc(S(=O)(=O)NCCCN2CCC(O)(c3ccc(Cl)cc3)CC2)cc1 CHEMBL258064 IC50 120.0 nM
CCCC(NC(=O)c1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180538 IC50 120.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(CN)c(Cl)c3C)CC2)ccc1Cl CHEMBL2322850 IC50 120.0 nM
COc1cc(N2CCN(C(=O)Cn3ncc(Cl)c3C)CC2)ccc1Cl CHEMBL2322871 IC50 120.0 nM
CS(=O)(=O)c1ccc(CNC(=O)c2cccc3c2cnn3-c2ccc(F)cc2)cn1 CHEMBL4471579 IC50 120.0 nM
O=C(N[C@@H](C(=O)N1CCC(c2ccc(Cl)cc2)CC1)C1CCCCC1)c1ccccc1 CHEMBL2180494 IC50 121.0 nM
CC[C@@H](NC(=O)c1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180527 IC50 121.0 nM
N#CCC(C#N)(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL143194 Ki 125.0 nM
O=C(NCC1CCCCC1)NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL341306 IC50 125.0 nM
COc1cc(N2CCC(C(N)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)c(Cl)cc1Cl CHEMBL4559982 Ki 125.0 nM
O=C(O)c1c(F)cccc1Oc1ccc(C(F)(F)F)cc1NS(=O)(=O)c1ccc(Cl)cc1 CHEMBL1170391 pKi 125.89 nM
O=C(O)c1ccccc1Oc1c(F)cc(C(F)(F)F)cc1NS(=O)(=O)c1ccc(Cl)cc1 CHEMBL1171006 pKi 125.89 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cccs1 CHEMBL346205 Ki 128.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)N1CCCCC1 CHEMBL357434 Ki 130.0 nM
CNC(=O)[C@H](CC(C)C)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1ccc2ccccc2n1 CHEMBL69978 IC50 130.0 nM
O=S(=O)(c1ccccc1Cl)N1CCC(N2CCCC(O)(c3ccc(Cl)cc3)CC2)CC1 CHEMBL404465 IC50 130.0 nM
O=S(=O)(c1ccccc1Cl)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 CHEMBL270253 IC50 130.0 nM
CC(C)CC(NC(=O)c1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180539 IC50 130.0 nM
O=C(c1ccc(F)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1ccccc1O2)N1CC[C@H](O)C1 CHEMBL2391801 IC50 130.0 nM
N#CC(CCCN1CCC(O)(c2ccc(F)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL2112832 Ki 136.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C(F)(F)F)cc2)C1C1CCCCC1 CHEMBL4483771 pKi 138.04 nM
O=C(NC1CCN(CC2CCCCCCC2)CC1)C1c2ccccc2Oc2ccccc21 CHEMBL33074 IC50 140.0 nM
CNc1c(Nc2cc(F)c(F)cc2OCC(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)c(=O)c1=O CHEMBL232455 IC50 140.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1Br CHEMBL429591 IC50 140.0 nM
Cc1ccc(CC(=O)N[C@@H](C(=O)N2CCC(c3ccc(Cl)cc3)CC2)C(C)C)cc1 CHEMBL2180189 IC50 140.0 nM
COc1cc(N2CCC(C(Cn3nc(C(F)(F)F)cc3C)NC(=O)CN)CC2)ccc1Cl CHEMBL4461035 Ki 145.0 nM
O=C(NC1CCN(C/C2=C/CCCCCC2)CC1)C1c2cc(Br)ccc2Oc2ccc(Br)cc21 CHEMBL33580 IC50 150.0 nM
CC[C@@H](NC(=O)CC(C)C)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180524 IC50 152.0 nM
CCCC(NC(=O)c1ccccc1C)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180541 IC50 152.0 nM
N#CC(CCCN1CCC(O)(c2ccc(C(F)(F)F)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL344075 Ki 153.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cccc(O)c1 CHEMBL341840 Ki 156.0 nM
COc1cc(N2CCC(C(O)Cn3nc(C(F)(F)F)nc3C)CC2)ccc1Cl CHEMBL4546480 Ki 156.0 nM
CNC(=O)[C@H](CC(C)C)C[C@H](O)[C@H](Cc1ccc(Cl)c(Cl)c1)NC(=O)c1cnc2ccccc2n1 CHEMBL71242 IC50 160.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1Nc1c(NCCN(C)C)c(=O)c1=O CHEMBL387821 IC50 160.0 nM
CNc1c(Nc2cc(F)ccc2OCC(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)c(=O)c1=O CHEMBL396700 IC50 160.0 nM
Cc1cc2c(OC[C@@H](O)CN3CCC4(CC3)Cc3cc(Cl)ccc3O4)cccc2o1 CHEMBL3099955 IC50 160.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1c1ccccc1 CHEMBL4448679 Ki 162.0 nM
Cc1ccccc1C1(O)CCN(CCCC2(C#N)c3ccccc3CSc3ccccc32)CC1 CHEMBL141829 Ki 164.0 nM
CCc1ccc(N2C(=O)C(O)=C(C(C)=O)C2C2CCCCC2)cc1 CHEMBL4441958 pKi 165.96 nM
O=C(NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1)Nc1ccncc1 CHEMBL332277 IC50 167.0 nM
CCCNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)c(=O)c1=O CHEMBL234081 IC50 170.0 nM
CCNS(=O)(=O)c1cccc(CNC(=O)c2cccc3c2cnn3-c2ccc(F)cc2)c1 CHEMBL4544186 IC50 170.0 nM
CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCC(O)(c2ccc(Br)cc2)CC1 CHEMBL2180531 IC50 172.0 nM
Cc1cccc(C)c1C(=O)N[C@@H](C(=O)N1CCC(c2ccc(Cl)cc2)CC1)C(C)C CHEMBL2180512 IC50 177.0 nM
O=S(=O)(c1ccccc1Cl)N1CCC(N2CCC(O)(c3ccc(Cl)c(Cl)c3)CC2)CC1 CHEMBL258359 IC50 180.0 nM
O=S(=O)(c1ccccc1Cl)N1CCC(N2CCC(O)(c3ccc(Br)cc3)CC2)CC1 CHEMBL271903 IC50 180.0 nM
Cc1ccccc1S(=O)(=O)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 CHEMBL404033 IC50 180.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cccc2ccccc12 CHEMBL270433 IC50 180.0 nM
CC(C)[C@@H](NC(=O)NCc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180521 IC50 180.0 nM
CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL2180548 IC50 180.0 nM
CC(C)NS(=O)(=O)c1cccc(CNC(=O)c2cccc3c2cnn3-c2ccc(F)cc2)c1 CHEMBL4577460 IC50 180.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1c1cccc(Br)c1 CHEMBL4467095 Ki 181.0 nM
Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N1CCN(c2ccc(Br)cc2)CC1 CHEMBL2322891 IC50 182.0 nM
CC(C)C(NC(=O)c1ccccc1)C(=O)N1CC=C(c2ccc(Cl)cc2)CC1 CHEMBL2180532 IC50 185.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1OC(F)(F)F CHEMBL258361 IC50 190.0 nM
CCCC(NC(=O)c1ccc2ccccc2c1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180545 IC50 191.0 nM
CC(C)[C@@H](NC(=O)[C@H]1CC[C@@H](N)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398721 IC50 194.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1c1ccc(C)cc1 CHEMBL4566226 pKi 194.98 nM
CC(C)[C@@H](NC(=O)c1ccc(Cl)cc1)C(=O)N1CC[C@](N)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398753 IC50 196.0 nM
CC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1c1cccc(Cl)c1 CHEMBL4547735 Ki 198.0 nM
CCOC(=O)C1=C(O)C(=O)N(c2ccc(C)cc2)C1C1CCCCC1 CHEMBL4442093 pKi 199.53 nM
O=C(NC1CCN(CC2CCCCC2)CC1)C1c2ccccc2Oc2ccccc21 CHEMBL34053 IC50 200.0 nM
CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)N1C2CCC1CN(Cc1ccc(F)cc1)C2 CHEMBL380568 IC50 200.0 nM
CNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(Cl)cc3)CC2)c(=O)c1=O CHEMBL390707 IC50 200.0 nM
N#CC1(CCCN2CCC(O)(c3ccccc3)CC2)c2ccccc2CSc2ccccc21 CHEMBL142244 Ki 203.0 nM
N#CC(CCCN1CCC(O)(c2cccnc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL141020 Ki 206.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc2ccccc2c1 CHEMBL342444 Ki 206.0 nM
CC(C)[C@@H](NC(=O)c1ccc(Cl)cc1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)C2(CCCC2)C1 CHEMBL2398759 IC50 208.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 CHEMBL256889 IC50 210.0 nM
CNC(=O)c1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)cc(OC)c1Cl CHEMBL2322884 IC50 210.0 nM
O=C(NCc1cccc(C(F)(F)F)c1)c1cccc2c1cnn2-c1ccc(Cl)cc1 CHEMBL4591935 IC50 210.0 nM
CNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(Cl)s3)C[C@H]2C)c(=O)c1=O CHEMBL234276 IC50 220.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)cc(C(=O)N(C)C)c1Cl CHEMBL2322885 IC50 220.0 nM
N#CC1(CCCN2CCC(O)(c3ccc(Cl)c(C(F)(F)F)c3)CC2)c2ccccc2CSc2ccccc21 CHEMBL143814 Ki 224.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1-c1cccs1 CHEMBL257452 IC50 230.0 nM
N#CC(CCCN1CCC(O)(c2ccc(I)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL142676 Ki 233.0 nM
CC(C)[C@@H](NC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398731 IC50 233.0 nM
N#CC1(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2Oc2ccccc21 CHEMBL143449 Ki 234.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccsc1 CHEMBL141387 Ki 236.0 nM
O=C(NCCCCO)NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL126978 IC50 240.0 nM
O=C(NC1CCN(C/C2=C/CCCCCC2)CC1)C1c2cc(Cl)ccc2Oc2ccc(Cl)cc21 CHEMBL33639 IC50 240.0 nM
NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL125111 Ki 244.0 nM
COc1ccc(N2C(=O)C(O)=C(C(C)=O)C2C2CCCCC2)cc1 CHEMBL4526524 pKi 251.19 nM
CC(C)(C)C(NC(=O)c1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180540 IC50 259.0 nM
CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CCC4C[C@@H](CCC=C(c5cc(Cl)c(OCc6ccccc6C(=O)[O-])c(C(=O)[O-])c5)c5cc(Cl)c(OCc6ccccc6C(=O)[O-])c(C(=O)[O-])c5)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL3138134 IC50 260.0 nM
CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CCC4C[C@@H](CCC=C(c5cc(Cl)c(O)c(C(=O)O)c5)c5cc(Cl)c(O)c(C(=O)O)c5)CC[C@]4(C)[C@H]3CC[C@]12C CHEMBL3138187 IC50 260.0 nM
O=C(CSc1nc2ccccc2s1)NC1CCN(Cc2ccc(Cl)cc2)CC1 CHEMBL282285 IC50 260.0 nM
O=C(NCc1cccc(C(F)(F)F)c1)c1cccc2c1cnn2-c1ccc(Cl)c(Cl)c1 CHEMBL4557554 IC50 260.0 nM
Cc1noc(C)c1S(=O)(=O)NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL1910159 IC50 261.0 nM
Cc1ccccc1C(=O)NC(C(=O)N1CCC(c2ccc(Cl)cc2)CC1)C(C)(C)C CHEMBL2180544 IC50 262.0 nM
CC(C)C(NC(=O)Oc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180517 IC50 265.0 nM
CNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(Br)cc3)C[C@H]2C)c(=O)c1=O CHEMBL232042 IC50 270.0 nM
Cc1cccc(Cl)c1S(=O)(=O)N1CCC[C@@H](N2CCC(O)(c3ccc(Cl)cc3)CC2)C1 CHEMBL402827 IC50 270.0 nM
CCN(Cc1ccc(Cl)cc1)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(Cl)cc1 CHEMBL454942 IC50 270.0 nM
CN(Cc1ccc(Cl)cc1)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(Cl)cc1 CHEMBL455162 IC50 270.0 nM
NC(=O)[C@H](Cc1ccccc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1 CHEMBL68551 IC50 280.0 nM
CC1CC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CCN1S(=O)(=O)c1ccccc1Cl CHEMBL256271 IC50 280.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cc(Cl)ccc1Cl CHEMBL270863 IC50 280.0 nM
COc1ccc(NC(=O)N2CCC[C@@H]2C(=O)N(C)Cc2ccc(Cl)cc2)cc1 CHEMBL517290 IC50 290.0 nM
O=C(NCCc1ccc(F)cc1)NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL333422 IC50 295.0 nM
CC(=O)Nc1cc(Cl)ccc1/C=C/C(=O)N1CC2CCC(C1)N2Cc1ccc(F)cc1 CHEMBL371248 IC50 300.0 nM
CC(C)C(NS(=O)(=O)Cc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180519 IC50 303.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1Cl CHEMBL356764 Ki 306.0 nM
O=C(NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1)NC1CCN(Cc2ccccc2)CC1 CHEMBL333063 IC50 310.0 nM
O=C(O)c1ccccc1Oc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1 CHEMBL1171758 pKi 316.23 nM
O=S(=O)(Nc1cc(Cl)c(Cl)cc1Cn1ccnn1)c1ccc(Cl)s1 CHEMBL2207100 pKi 316.23 nM
O=S(=O)(Nc1cc(Cl)c(Cl)cc1Cn1ccnn1)c1ccc(Cl)c(Cl)c1 CHEMBL2207098 pKi 316.23 nM
CC(C)CC(NC(=O)c1ccccc1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL2180550 IC50 324.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1c(F)c(F)c(F)c(F)c1F CHEMBL143772 Ki 330.0 nM
O=S(=O)(c1c(F)cc(F)cc1Br)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 CHEMBL256887 IC50 330.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(N)c(Cl)c3C)CC2)ccc1Cl CHEMBL2322848 IC50 340.0 nM
CC(C)[C@@H](NC(=O)[C@@H]1CC[C@@H](N)C1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL2398719 IC50 341.0 nM
COc1ccc(C2(O)CCN(CCCC(C#N)(c3ccccc3)c3ccccc3)CC2)cc1 CHEMBL141713 Ki 347.0 nM
CNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccccc3)C[C@H]2C)c(=O)c1=O CHEMBL231830 IC50 350.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cccc(Cl)c1Cl CHEMBL258360 IC50 350.0 nM
Cc1cc(C(=O)NCc2cccc(C(F)(F)F)c2)c(C)n1-c1ccc(Cl)cc1 CHEMBL4456839 IC50 350.0 nM
CCC(NC(=O)C1CCCC1)C(O)C1CCN(c2ccc(Cl)cc2)CC1 CHEMBL4449875 Ki 354.0 nM
COc1ccc(C(C#N)CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)cc1 CHEMBL141817 Ki 359.0 nM
O=C(NCCN1CCCCC1)NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL339752 IC50 360.0 nM
CC(=O)Nc1cc(Cl)ccc1CCC(=O)N1CCN(Cc2ccc(F)cc2)C[C@H]1C CHEMBL381446 IC50 360.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1Cl CHEMBL411477 IC50 360.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1Br CHEMBL357445 Ki 366.0 nM
O=C(NC1CC[N+](Cc2ccccc2)(CC2CCCCCCC2)CC1)C1c2ccccc2Oc2ccccc21 CHEMBL33586 IC50 370.0 nM
Cc1cccc(Cl)c1S(=O)(=O)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 CHEMBL269956 IC50 370.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1 CHEMBL404732 IC50 370.0 nM
C/C=C(/NC(=O)c1ccccc1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL2180547 IC50 370.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1F CHEMBL142160 Ki 371.0 nM
CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1 CHEMBL2180536 IC50 375.0 nM
N#CC(CCCN1CCC(O)(c2cccc(Cl)c2)CC1)(c1ccccc1)c1ccccc1 CHEMBL142713 Ki 385.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccsc1 CHEMBL270564 IC50 385.0 nM
O=C(NCCCCN1CCC(Oc2ccc(F)cc2)C1)NCc1ccc(Br)cc1 CHEMBL1910160 IC50 387.0 nM
CC(C)C(=O)NC(C(=O)N1CCC(c2ccc(Cl)cc2)CC1)C(C)C CHEMBL2180537 IC50 388.0 nM
Cc1nnnn1Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 CHEMBL2207084 pKi 398.11 nM
O=S(=O)(Nc1cc(Cl)ccc1Cn1ccnn1)c1ccc(Cl)c(Cl)c1 CHEMBL2207081 pKi 398.11 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)C1CCCCC1 CHEMBL143266 Ki 400.0 nM
N#CC(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL357919 IC50 400.0 nM
NCCNC(=O)c1ccc(O)cc1OC[C@@H](O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 CHEMBL2391936 IC50 400.0 nM
N#CC1(CCCN2CCC(O)(Cc3ccccc3)CC2)c2ccccc2CSc2ccccc21 CHEMBL342721 Ki 405.0 nM
COC(=O)C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 CHEMBL356718 Ki 406.0 nM
CC(C)CCC[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(N)=O CHEMBL69816 IC50 420.0 nM
O=S(=O)(c1c(Cl)cccc1Cl)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 CHEMBL270254 IC50 420.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2)cc(C(=O)O)c1Cl CHEMBL2322882 IC50 420.0 nM
CNS(=O)(=O)c1ccc(CNC(=O)c2cnn(-c3ccc(Cl)cc3)c2C)cc1 CHEMBL4574870 IC50 420.0 nM
CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCC(c2ccc(F)cc2)CC1 CHEMBL2180533 IC50 423.0 nM
Cn1cccc1C(C#N)CCCN1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL143840 Ki 429.0 nM
Cc1cccc(Cl)c1S(=O)(=O)N1CCC[C@H](N2CCC(O)(c3ccc(Cl)cc3)CC2)C1 CHEMBL409498 IC50 430.0 nM
O=S(=O)(c1ccccc1Cl)N1CCC(N2CCC(O)(c3ccc(Cl)c(F)c3)CC2)CC1 CHEMBL404757 IC50 430.0 nM
CC(C)(F)CCC(C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(=O)NCc1ccccc1 CHEMBL65784 IC50 440.0 nM
O=C(CSc1nc2ccccc2s1)NC1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 CHEMBL20532 IC50 450.0 nM
O=C(NCc1cccc(Cl)c1)c1cccc2c1cnn2-c1ccc(F)cc1 CHEMBL4568987 IC50 450.0 nM
O=C(NCc1cccc(C(F)(F)F)c1)c1nccc2c1cnn2-c1ccc(F)cc1 CHEMBL4445316 IC50 450.0 nM
CC(C#N)(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 CHEMBL143825 Ki 460.0 nM
O=S(=O)(c1ccccc1Br)N1CCC[C@H](N2CCC(O)(c3ccc(Cl)cc3)CC2)C1 CHEMBL255797 IC50 460.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1 CHEMBL143942 Ki 463.0 nM
CC(C)(O)CC[C@@H](CN)C[C@H](O)[C@H](Cc1cccc(F)c1)NC(=O)c1cnc2ccccc2n1 CHEMBL234606 IC50 480.0 nM
CC(=O)C1=C(O)C(=O)N(c2cccc(C)c2)C1C1CCCCC1 CHEMBL4552420 pKi 489.78 nM
COc1cc(C(C#N)CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)cc(OC)c1OC CHEMBL143690 Ki 497.0 nM
COC(=O)N1CCC(NC(=O)NCC(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)(c2ccccc2)c2ccccc2)CC1 CHEMBL124585 IC50 500.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(NC(C)=O)c3C)CC2)ccc1Cl CHEMBL2322862 IC50 500.0 nM
Cc1c(C(=O)NCc2cccc(C(F)(F)F)c2)cnn1-c1ccc(Cl)c(Cl)c1 CHEMBL4539264 IC50 500.0 nM
O=C(O)c1ccccc1Oc1ccc(C(F)(F)F)cc1NS(=O)(=O)c1ccc(Cl)cc1 CHEMBL1171586 pKi 501.19 nM
O=S(=O)(Nc1cc(Cl)ccc1Cn1ccnn1)c1cc(Cl)c(Cl)s1 CHEMBL2207094 pKi 501.19 nM
O=S(=O)(Nc1cc(Cl)ccc1Cn1nnnc1C1CC1)c1ccc(Cl)c(Cl)c1 CHEMBL2207080 pKi 501.19 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cccc([N+](=O)[O-])c1 CHEMBL423734 Ki 510.0 nM
CCCCCCN1CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1 CHEMBL34226 IC50 510.0 nM
CNC(=O)[C@H](CC(C)C)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cncc(Br)c1 CHEMBL67256 IC50 510.0 nM
O=S(=O)(c1ccccc1Cl)N1CCC(N2CCC(O)(c3ccc(F)c(Cl)c3)CC2)CC1 CHEMBL403613 IC50 510.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc2ccccc2c1 CHEMBL271079 IC50 520.0 nM
CCCC(NC(=O)c1ccccc1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL2180549 IC50 521.0 nM
CC(=O)C1=C(O)C(=O)N(c2cccc(Cl)c2)C1C1CCCCC1 CHEMBL4472384 pKi 524.81 nM
CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCN(c2ccc(Cl)cc2)CC1 CHEMBL2180535 IC50 525.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 CHEMBL142161 Ki 533.0 nM
COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(C)cc2)cc1 CHEMBL1500746 pKi 537.03 nM
CSCCC(NC(=O)c1ccccc1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL2180551 IC50 539.0 nM
O=C([C@H]1CCCN1C(=O)Nc1ccc(Cl)cc1)N(CCO)Cc1ccc(Cl)cc1 CHEMBL454940 IC50 540.0 nM
CC(C)[C@@H](NC(=O)NCCc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180522 IC50 543.0 nM
N[C@H](COc1cccc2ccc(=O)[nH]c12)CN1CCC2(CC1)Cc1cc(F)ccc1O2 CHEMBL3099959 IC50 560.0 nM
O=c1[nH]c(=O)c2cccc(OC[C@@H](O)CN3CCC4(CC3)Cc3cc(Cl)ccc3O4)c2[nH]1 CHEMBL3099954 IC50 560.0 nM
CC(C)(O)CC[C@H](C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(N)=O CHEMBL66457 IC50 580.0 nM
CNC(=O)[C@H](CC(C)C)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1nccc2ccccc12 CHEMBL302328 IC50 580.0 nM
CC1(C)CN(C(=O)[C@H]2CCCC[C@H]2NC(=O)[C@@H](O)c2ccccc2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679649 IC50 580.6 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccn1 CHEMBL358596 Ki 584.0 nM
N#CC1(c2ccc(Cl)cc2)CCN(CCCNS(=O)(=O)c2ccccc2Cl)CC1 CHEMBL404301 IC50 600.0 nM
Cc1c(C(=O)NCc2cccc(C(F)(F)F)c2)cnn1-c1ccc(Cl)cc1 CHEMBL4440166 IC50 600.0 nM
CNC(=O)[C@H](CC(C)C)C[C@H](O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cnc2ccccc2n1 CHEMBL308209 IC50 610.0 nM
CC(C)[C@@H](NC(=O)Nc1ccccc1)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 CHEMBL2180520 IC50 616.0 nM
N#CC1(CCCN2CCC(O)(c3cccc(C(F)(F)F)c3)CC2)c2ccccc2CSc2ccccc21 CHEMBL341769 Ki 623.0 nM
CNC(=O)[C@H](CC(C)C)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2c1 CHEMBL69411 IC50 650.0 nM
CNC(=O)[C@H](CC(C)C)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)c1cnc2ccccc2n1 CHEMBL71903 IC50 670.0 nM
O=S(=O)(c1ccc(Cl)c(Cl)c1Cl)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 CHEMBL258369 IC50 670.0 nM
Cc1ccc(NC(=O)N2CCC[C@@H]2C(=O)N(C)Cc2ccc(Cl)cc2)cc1 CHEMBL461590 IC50 680.0 nM
CN(Cc1ccc(Cl)cc1)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(F)cc1 CHEMBL516495 IC50 700.0 nM
N#CC(CCCN1CCC(O)(c2ccc3ccccc3c2)CC1)(c1ccccc1)c1ccccc1 CHEMBL140270 Ki 715.0 nM
CN(Cc1ccc(Cl)cc1)C(=O)[C@H]1CCCN1C(=O)Nc1ccc(C#N)cc1 CHEMBL462441 IC50 720.0 nM
CC(C)(F)CCC(C[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C(=O)N1CCCC1 CHEMBL68692 IC50 740.0 nM
COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C(F)(F)F)CC2)ccc1Cl CHEMBL2322864 IC50 740.0 nM
O=C(NCc1cccc(C(F)(F)F)c1)c1cccc2c1cnn2-c1ccccc1 CHEMBL4458721 IC50 750.0 nM
CC1(C)CN(C(=O)[C@H]2CCCC[C@H]2NC(=O)CO)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679647 IC50 767.5 nM
COc1ccc(NC(=O)NCC(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)(c2ccccc2)c2ccccc2)cc1 CHEMBL124084 IC50 780.0 nM
O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cc(Cl)cc(Cl)c1 CHEMBL257698 IC50 780.0 nM
CC(C)(CC(=O)N1CCC(O)(c2ncc(Cl)cc2Cl)C(C)(C)C1)NC(=O)c1ccccc1 CHEMBL4559773 IC50 787.8 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1O CHEMBL142798 Ki 790.0 nM
Cc1c(C(=O)NCc2cccc(C(F)(F)F)c2)cnn1-c1ccc(F)cc1 CHEMBL4449368 IC50 790.0 nM
Cc1ccnc2c1ccc1c(C)ccnc12 CHEMBL593442 pEC50 794.33 nM
O=C(NC1CCN(CC2CCCCCCCCC2)CC1)C1c2ccccc2Oc2ccccc21 CHEMBL285703 IC50 800.0 nM
C[N+]1(CC2CCCCCCC2)CCC(NC(=O)C(c2ccccc2)c2ccccc2)CC1 CHEMBL33761 IC50 800.0 nM
COc1cc2c(cc1Cl)NC(=O)NC2CC(=O)N1CCN(Cc2ccc(F)cc2)C[C@H]1C CHEMBL381223 IC50 800.0 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1Nc1c(NCc2ccccc2)c(=O)c1=O CHEMBL397956 IC50 800.0 nM
CC(C)[C@@H](CNC(=O)Cc1ccccc1)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL4468705 IC50 808.9 nM
Cc1nc([C@H]2CCCN2C(=O)Nc2ccc(C(F)(F)F)cc2)n(Cc2ccc(Cl)cc2)n1 CHEMBL1224121 IC50 810.0 nM
CC1(C)CN(C(=O)[C@H]2CCCC[C@@]2(C)NC(=O)c2ccccc2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679658 IC50 818.0 nM
COc1ccc(S(=O)(=O)NCCCN2CCC(O)(c3ccc(Cl)cc3)CC2)cc1 CHEMBL272559 IC50 830.0 nM
CNC(=O)[C@H](CC(C)C)C[C@H](O)[C@H](CC1CCCCC1)NC(=O)c1cnc2ccccc2c1 CHEMBL68937 IC50 840.0 nM
CC(C)C(NC(=O)OCc1ccccc1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1 CHEMBL2180529 IC50 854.0 nM
CC1(C)CN(C(=O)[C@H]2CCCC[C@H]2NC(=O)[C@H](O)c2ccccc2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679648 IC50 857.8 nM
C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1 CHEMBL234622 IC50 860.0 nM
O=C(NCC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1)Nc1ccc(C(F)(F)F)cc1 CHEMBL333865 IC50 890.0 nM
N#CC(CCCN1CCC(O)(c2ccccn2)CC1)(c1ccccc1)c1ccccc1 CHEMBL358283 Ki 906.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1cccc(Oc2ccccc2)c1 CHEMBL142263 Ki 908.0 nM
CNc1c(Nc2ccccc2OCC(=O)N2CCN(Cc3ccc(F)cc3)C[C@H]2C)c(=O)c1=O CHEMBL232252 IC50 920.0 nM
CC1(C)CN(C(=O)[C@H]2CCCC[C@H]2NC(=O)CCN2CCCCC2)CC[C@]1(O)c1ccc(Cl)cc1 CHEMBL3679645 IC50 931.8 nM
CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCC(O)(c2ccc(F)cc2)CC1 CHEMBL2180530 IC50 933.0 nM
Cc1c(C(=O)NCc2cccc(C(F)(F)F)c2)cnn1-c1ccc([N+](=O)[O-])cc1 CHEMBL4538794 IC50 960.0 nM
O=S(=O)(c1cccs1)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 CHEMBL258368 IC50 970.0 nM
N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(O)cc1 CHEMBL145106 Ki 975.0 nM
CCOC(=O)c1cc(C2(O)CCN(C(=O)CC(C)(C)NC(=O)c3ccccc3)CC2(C)C)ccc1Cl CHEMBL4522473 IC50 991.4 nM
COC(=O)N[C@@H]1CCCC[C@@H]1C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 CHEMBL3679643 IC50 996.7 nM