COCCO[C@H]1CC[C@H](Nc2cc(=O)n(C)c3ccc(-c4cncs4)cc23)CC1 CHEMBL3426034 Ki 0.3 nM
O=C(Nc1cccc(F)c1)c1ccnc(-n2ccnc2)n1 CHEMBL5410644 IC50 0.3 nM
CO[C@H]1CC[C@H](Nc2cc(=O)n(C)c3c(C)cc(-c4cncs4)cc23)CC1 CHEMBL3426039 Ki 0.45 nM
COCCO[C@H]1CC[C@H](Nc2cc(=O)n(C)c3c(C)cc(-c4cncs4)cc23)CC1 CHEMBL3426035 Ki 0.7 nM
O=C(Nc1ccc(Cl)c(F)c1)c1ccnc(-n2ccnc2)n1 CHEMBL5401022 IC50 1.3 nM
O=C(Nc1cccc(Cl)c1)c1ccnc(-n2ccnc2)n1 CHEMBL5418653 IC50 1.3 nM
CNC(=O)[C@H]1CC[C@H](Nc2cc(=O)[nH]c3c(C)cc(-c4cncs4)cc23)CC1 CHEMBL3426065 IC50 1.4 nM
O=C(Nc1cc(F)cc(F)c1)c1ccnc(-n2ccnc2)n1 CHEMBL5436403 IC50 1.4 nM
O=C(Nc1ccc(C(F)(F)F)cc1)c1ccnc(-n2ccnc2)n1 CHEMBL5426011 IC50 1.4 nM
O=C(Nc1ccc(F)c(F)c1)c1ccnc(-n2ccnc2)n1 CHEMBL5398114 IC50 1.5 nM
N#Cc1ccc(NC(=O)c2ccnc(-n3ccnc3)n2)cc1 CHEMBL5434460 IC50 1.5 nM
O=C(Nc1ccc(F)cc1)c1ccnc(-n2ccnc2)n1 CHEMBL5425216 IC50 1.5 nM
O=C(Nc1ccc(Cl)cc1)c1ccnc(-n2ccnc2)n1 CHEMBL5440681 IC50 1.6 nM
Cc1ccc(NC(=O)c2ccnc(-n3ccnc3)n2)cc1 CHEMBL5440312 IC50 2.0 nM
O=C(Nc1ccncc1)c1ccnc(-n2ccnc2)n1 CHEMBL5427901 IC50 2.0 nM
Cc1cccc(NC(=O)c2ccnc(-n3ccnc3)n2)c1 CHEMBL5405079 IC50 2.4 nM
CNC(=O)[C@H]1CC[C@H](Nc2cc(=O)[nH]c3ccc(-c4cncs4)cc23)CC1 CHEMBL3426064 IC50 3.4 nM
CO[C@H]1CC[C@H](Nc2cc(=O)[nH]c3c(C)cc(-c4cncs4)cc23)CC1 CHEMBL3426037 IC50 3.8 nM
O=C(Nc1ccncc1)c1cc(C(F)(F)F)nc(-n2ccnc2)n1 CHEMBL5414411 IC50 3.8 nM
COCCO[C@H]1CC[C@H](Nc2cc(=O)[nH]c3c(C)cc(-c4cncs4)cc23)CC1 CHEMBL3426033 IC50 3.9 nM
NC(=O)c1cccc2c1NC(N1Cc3c(N)n[nH]c3C13CC3)=NC2NCc1c(F)cccc1C(F)(F)F CHEMBL4229241 IC50 4.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3c([N+](=O)[O-])c[nH]c23)CC1 CHEMBL5178786 IC50 4.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cnn(C)c3)nc(-n3ccnc3)n2)CC1 CHEMBL5076763 IC50 4.2 nM
CNC(=O)[C@H]1CC[C@H](Nc2cc(=O)n(C)c3ccc(-c4cncs4)cc23)CC1 CHEMBL3426066 IC50 4.8 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cnn(C)c3)cc(-n3ccnc3)n2)CC1 CHEMBL5083478 IC50 5.0 nM
O=C(Nc1cccc(F)c1)c1cc(C(F)(F)F)nc(-n2ccnc2)n1 CHEMBL5424500 IC50 5.0 nM
O=C(Nc1cccnc1)c1cc(C(F)(F)F)nc(-n2ccnc2)n1 CHEMBL5396888 IC50 5.0 nM
CNC(=O)[C@H]1CC[C@H](Nc2cc(=O)n(C)c3c(C)cc(-c4cncs4)cc23)CC1 CHEMBL3426067 IC50 5.3 nM
COCCO[C@H]1CC[C@H](Nc2cc(=O)[nH]c3ccc(-c4cncs4)cc23)CC1 CHEMBL3426032 IC50 6.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc(-n3ccnc3)n2)CC1 CHEMBL5091229 IC50 6.8 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)cc(-n3ccnc3)n2)CC1 CHEMBL5076855 IC50 7.0 nM
NC(=O)c1cccc2c1NC(N1Cc3c(N)n[nH]c3C13CCC3)=NC2NCc1c(F)cccc1C(F)(F)F CHEMBL4225752 IC50 7.8 nM
O=C(Nc1ccnnc1)c1cc(C(F)(F)F)nc(-n2ccnc2)n1 CHEMBL5420517 IC50 9.8 nM
O=C(NC1CCCCCC1)c1ccnc(-n2ccnc2)n1 CHEMBL5417850 IC50 10.0 nM
COCCOc1ncc(NC(=O)c2cc(C(F)(F)F)nc(-n3ccnc3)n2)cn1 CHEMBL5403262 IC50 11.0 nM
O=C(Nc1cncs1)c1ccnc(-n2ccnc2)n1 CHEMBL5424631 IC50 11.0 nM
COCCO[C@H]1CC[C@H](NC(=O)C2=CC(c3cncs3)=CC3NC(=O)NC23)CC1 CHEMBL5176492 IC50 12.0 nM
C[C@H]1CC[C@@H](NC(=O)c2ccnc(-n3ccnc3)n2)CC1 CHEMBL5430964 IC50 12.0 nM
O=C(NC1CCC(F)(F)CC1)c1ccnc(-n2ccnc2)n1 CHEMBL5431367 IC50 12.0 nM
CO[C@H]1CC[C@H](Nc2cc(=O)n(C)c3ccc(-c4cncs4)cc23)CC1 CHEMBL3426038 IC50 13.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)cc3cc[nH]c23)CC1 CHEMBL5172217 IC50 13.0 nM
O=C(Nc1cncnc1)c1cc(C(F)(F)F)nc(-n2ccnc2)n1 CHEMBL5437449 IC50 13.0 nM
Cn1c(=O)cc(N[C@H]2CC[C@H](O)CC2)c2cc(-c3cncs3)ccc21 CHEMBL3426040 IC50 14.0 nM
Cn1c(=O)cc(NC2CCOCC2)c2cc(-c3cncs3)ccc21 CHEMBL3426030 Ki 14.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)cc3[nH]cc(C#N)c23)CC1 CHEMBL5196986 IC50 16.0 nM
NC(=O)c1cccc2c1NC(N1Cc3c(N)n[nH]c3C13CCCC3)=NC2NCc1c(F)cccc1C(F)(F)F CHEMBL4224903 IC50 17.0 nM
O=C(NC1CCCCCCC1)c1ccnc(-n2ccnc2)n1 CHEMBL5434181 IC50 17.0 nM
CC1(C)c2[nH]nc(N)c2CN1C1=NC(NCc2c(F)cccc2C(F)(F)F)c2cccc(C(N)=O)c2N1 CHEMBL4224854 IC50 20.0 nM
Cc1n[nH]c2c1CN(C1=NC(NCc3c(F)cccc3C(F)(F)F)c3cccc(C(N)=O)c3N1)[C@@H]2C CHEMBL4226017 IC50 21.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3cn[nH]c23)CC1 CHEMBL5205975 IC50 21.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2ccnc(-n3ccnc3)n2)CC1 CHEMBL5397412 IC50 21.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)nc3[nH]ccc23)CC1 CHEMBL5172896 IC50 22.0 nM
CO[C@H]1CC[C@H](NC(=O)c2ccnc(-n3ccnc3)n2)CC1 CHEMBL5432974 IC50 22.0 nM
CC1(C)CCC(NC(=O)c2ccnc(-n3ccnc3)n2)CC1 CHEMBL5423247 IC50 24.0 nM
CO[C@H]1CC[C@H](Nc2nc(O)nc3c(C)cc(-c4cncs4)cc23)CC1 CHEMBL3426058 IC50 26.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3c(C(C)O)c[nH]c23)CC1 CHEMBL5195341 IC50 26.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)nc3cc[nH]c23)CC1 CHEMBL5204685 IC50 27.0 nM
Cc1cc(-c2cncs2)cc2c(Nc3ccc(F)c(Cl)c3)nc(O)nc12 CHEMBL3426057 IC50 28.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3c(C#N)c[nH]c23)CC1 CHEMBL5191259 IC50 28.0 nM
O=C(NC1CCCC1)c1ccnc(-n2ccnc2)n1 CHEMBL5436110 IC50 30.0 nM
CO[C@H]1CC[C@H](NC(=O)c2cncc(-n3ccnc3)n2)CC1 CHEMBL5427100 IC50 32.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cnn(C)c3)nc(-c3cncs3)c2)CC1 CHEMBL5070314 IC50 34.0 nM
O=C(N[C@H]1CC[C@H](O)CC1)c1cc(-c2cncs2)cc2[nH]ccc12 CHEMBL5171265 IC50 37.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3c(C(F)(F)F)c[nH]c23)CC1 CHEMBL5198750 IC50 41.0 nM
CNC(=O)[C@H]1CC[C@H](Nc2nc(C)nc3c(C(F)(F)F)cc(-c4cncs4)cc23)CC1 CHEMBL3426061 IC50 42.0 nM
Cc1n[nH]c2c1CN(C1=NC(NCc3c(F)cccc3C(F)(F)F)c3cccc(C(N)=O)c3N1)C2 CHEMBL4226243 IC50 42.0 nM
C[C@@H]1c2[nH]nc(N)c2CN1C1=NC(NCc2c(F)cccc2C(F)(F)F)c2cccc(C(N)=O)c2N1 CHEMBL4226271 IC50 45.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3c(C(N)=O)c[nH]c23)CC1 CHEMBL5197813 IC50 47.0 nM
C[C@@H]1CCCC[C@@H]1Nc1ncnc2ccc(-c3cncs3)cc12 CHEMBL3426188 IC50 49.0 nM
C[C@H]1CC[C@H](NC(=O)c2ccnc(-n3ccnc3)n2)CC1 CHEMBL5429970 IC50 49.0 nM
CNC(=O)[C@H]1CC[C@H](Nc2nc(C)nc3c(C)cc(-c4cncs4)cc23)CC1 CHEMBL3426063 IC50 50.0 nM
C[C@@H]1c2n[nH]cc2CN1C1=NC(NCc2c(F)cccc2C(F)(F)F)c2cccc(C(N)=O)c2N1 CHEMBL4227839 IC50 51.0 nM
CO[C@H]1CC[C@H](NC(=O)c2cccc(-n3ccnc3)n2)CC1 CHEMBL5415804 IC50 51.0 nM
Cc1cc(-c2cncs2)cc2c(NC3CCOCC3)cc(=O)n(C)c12 CHEMBL3426031 IC50 52.0 nM
CO[C@H]1CC[C@H](Nc2nc(=O)n(C)c3ccc(-c4cncs4)cc23)CC1 CHEMBL3426060 IC50 53.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cnn(C)c3)nc(-c3cncs3)n2)CC1 CHEMBL5072634 IC50 53.0 nM
CCn1c(=O)cc(N[C@H]2CC[C@H](OCCOC)CC2)c2cc(-c3cncs3)ccc21 CHEMBL3426036 IC50 54.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)cc3[nH]ccc23)CC1 CHEMBL5207157 IC50 54.0 nM
Cc1cc(-c2cncs2)cc2c(NC3CCOCC3)cc(=O)[nH]c12 CHEMBL3426029 IC50 55.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3c(CO)c[nH]c23)CC1 CHEMBL5173157 IC50 56.0 nM
CCn1c(=O)cc(N[C@H]2CC[C@H](C(=O)NC)CC2)c2cc(-c3cncs3)ccc21 CHEMBL3426027 IC50 58.0 nM
CNC(=O)c1c[nH]c2c(C(=O)N[C@H]3CC[C@H](OCCOC)CC3)cc(-n3ccnc3)cc12 CHEMBL5175275 IC50 59.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2nc(-c3cncs3)nc3[nH]ccc23)CC1 CHEMBL5209327 IC50 59.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)nc(-n3ccnc3)c2)CC1 CHEMBL5082935 IC50 60.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3cc[nH]c23)CC1 CHEMBL5186368 IC50 60.0 nM
O=c1cc(NC2CCOCC2)c2cc(-c3cncs3)ccc2[nH]1 CHEMBL3426028 IC50 61.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)c(F)c3[nH]ccc23)CC1 CHEMBL5192931 IC50 61.0 nM
COCCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)cc3[nH]ccc23)CC1 CHEMBL5207349 IC50 63.0 nM
COCCO[C@H]1CC[C@H](Nc2nc(=O)n(C)c3ccc(-c4cncs4)cc23)CC1 CHEMBL3426059 IC50 64.0 nM
CC[C@@H]1c2[nH]ncc2CN1C1=NC(NCc2c(F)cccc2C(F)(F)F)c2cccc(C(N)=O)c2N1 CHEMBL4226629 IC50 71.0 nM
NC(=O)c1cccc2c(NCc3c(F)cccc3C(F)(F)F)cc(NCc3cn[nH]c3)nc12 CHEMBL4227109 IC50 72.0 nM
Cc1cc(NCc2c(Cl)ccc(Cl)c2Cl)c2cc(F)cc(C(N)=O)c2n1 CHEMBL3604758 IC50 76.0 nM
NC(=O)[C@H]1CC[C@H](Nc2ncnc3ccc(-c4cncs4)cc23)CC1 CHEMBL3426191 IC50 78.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)nc3c2ccn3C)CC1 CHEMBL5189168 IC50 80.0 nM
Cn1ncc2c1CN(C1=NC(NCc3c(F)cccc3C(F)(F)F)c3cccc(C(N)=O)c3N1)C2 CHEMBL4227578 IC50 82.0 nM
CCc1n[nH]c2c1CN(C1=NC(NCc3c(F)cccc3C(F)(F)F)c3cccc(C(N)=O)c3N1)C2 CHEMBL4227062 IC50 83.0 nM
CO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3[nH]c(=O)[nH]c23)CC1 CHEMBL5395994 IC50 87.0 nM
CCNC(=O)[C@H]1CC[C@H](Nc2ncnc3ccc(-c4cncs4)cc23)CC1 CHEMBL3426193 IC50 92.0 nM
NC(=O)c1cccc2c(NCc3c(F)cccc3C(F)(F)F)nc(N3Cc4cn[nH]c4C3)nc12 CHEMBL4227304 IC50 92.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)cc3c2ccn3C)CC1 CHEMBL5191920 IC50 94.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3c(C(=O)N(C)C)c[nH]c23)CC1 CHEMBL5194298 IC50 103.0 nM
NC(=O)c1cccc2c1NC(N1Cc3[nH]nc(N)c3C1)=NC2NCc1c(F)cccc1C(F)(F)F CHEMBL4225684 IC50 110.0 nM
C[C@H](O)c1n[nH]c2c1CN(C1=NC(NCc3c(F)cccc3C(F)(F)F)c3cccc(C(N)=O)c3N1)C2 CHEMBL4226909 IC50 110.0 nM
CO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3cn[nH]c23)CC1 CHEMBL5404154 IC50 110.0 nM
CO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3cc[nH]c23)CC1 CHEMBL5405886 IC50 110.0 nM
CC1CCC(Nc2ncnc3ccc(-c4cncs4)cc23)CC1 CHEMBL3426186 IC50 117.0 nM
Cc1cc(NCc2c(F)ccc(Cl)c2Cl)c2cccc(C(N)=O)c2n1 CHEMBL3604739 IC50 130.0 nM
c1nc(NC2CCCCC2)c2cc(-c3cncs3)ccc2n1 CHEMBL3426094 IC50 132.0 nM
C[C@H]1CCCC[C@@H]1Nc1ncnc2ccc(-c3cncs3)cc12 CHEMBL3426187 IC50 140.0 nM
CC(=O)c1n[nH]c2c1CN(C1=NC(NCc3c(F)cccc3C(F)(F)F)c3cccc(C(N)=O)c3N1)C2 CHEMBL4226529 IC50 140.0 nM
CC1CCCC(Nc2ncnc3ccc(-c4cncs4)cc23)C1 CHEMBL3426189 IC50 142.0 nM
NC(=O)N1CCC(Nc2ncnc3ccc(-c4cncs4)cc23)CC1 CHEMBL3426184 IC50 149.0 nM
Cc1cc(NCc2c(Cl)ccc(Cl)c2Cl)c2cccc(C(N)=O)c2n1 CHEMBL3604735 IC50 150.0 nM
Cn1cc2c(n1)CN(C1Nc3c(C(N)=O)cccc3C(NCc3c(F)cccc3C(F)(F)F)N1)C2 CHEMBL4226721 IC50 160.0 nM
Cc1cc(NCc2c(F)ccc(F)c2Cl)c2cccc(C(N)=O)c2n1 CHEMBL3604737 IC50 170.0 nM
Cc1n[nH]c2c1CN(C1=NC(NCc3c(F)cccc3C(F)(F)F)c3cccc(C(N)=O)c3N1)[C@H]2C CHEMBL4225165 IC50 170.0 nM
CO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)c[nH]c2=O)CC1 CHEMBL5403659 IC50 190.0 nM
CO[C@H]1CC[C@H](NC(=O)c2cncc(-c3cn[nH]c3)n2)CC1 CHEMBL5434557 IC50 200.0 nM
Cc1cc(-c2cncs2)cc2c(Nc3ccc(F)c(Cl)c3)ncnc12 CHEMBL3426056 IC50 206.0 nM
COCCOC12CCC(NC(=O)c3cc(-c4cncs4)cc4[nH]ccc34)(CC1)C2 CHEMBL5173927 IC50 219.0 nM
CO[C@H]1CC[C@H](NC(=O)c2nccc(-n3ccnc3)n2)CC1 CHEMBL5395515 IC50 220.0 nM
C[C@@H](O)c1n[nH]c2c1CN(C1=NC(NCc3c(F)cccc3C(F)(F)F)c3cccc(C(N)=O)c3N1)C2 CHEMBL4228311 IC50 230.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3c(Cl)c[nH]c23)CC1 CHEMBL5181391 IC50 238.0 nM
CNC(=O)[C@H]1CC[C@H](Nc2nc(C(F)(F)F)nc3c(C)cc(-c4cncs4)cc23)CC1 CHEMBL3426062 IC50 245.0 nM
NC(=O)c1ccc(Nc2ncnc3c(C(F)(F)F)cc(-c4cncs4)cc23)cc1 CHEMBL3426055 IC50 263.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2cc(-c3cncs3)cc3[nH]ccc23)C1 CHEMBL5191444 IC50 265.0 nM
Cc1cc(NCc2c(F)ccc(C)c2Cl)c2cccc(C(N)=O)c2n1 CHEMBL3604740 IC50 280.0 nM
c1nc(NC2CCCC2)c2cc(-c3cncs3)ccc2n1 CHEMBL3426093 IC50 281.0 nM
Fc1ccc(Nc2ccnc3ccc(-c4cncs4)cc23)cc1Cl CHEMBL3426068 IC50 298.0 nM
C[C@H]1c2[nH]nc(N)c2CN1C1=NC(NCc2c(F)cccc2C(F)(F)F)c2cccc(C(N)=O)c2N1 CHEMBL4225439 IC50 310.0 nM
CCn1ccc2c(C(=O)N[C@H]3CC[C@H](OCCOC)CC3)cc(-c3cncs3)nc21 CHEMBL5205105 IC50 319.0 nM
C[C@@H]1c2cn[nH]c2CN1C1=NC(NCc2c(F)cccc2C(F)(F)F)c2cccc(C(N)=O)c2N1 CHEMBL4226170 IC50 330.0 nM
CC[C@H]1c2[nH]ncc2CN1C1=NC(NCc2c(F)cccc2C(F)(F)F)c2cccc(C(N)=O)c2N1 CHEMBL4226213 IC50 370.0 nM
OC1CCC(Nc2ncnc3ccc(-c4cncs4)cc23)CC1 CHEMBL3426190 IC50 406.0 nM
C[C@H]1c2n[nH]cc2CN1C1=NC(NCc2c(F)cccc2C(F)(F)F)c2cccc(C(N)=O)c2N1 CHEMBL4226985 IC50 410.0 nM
NC(=O)c1cccc2c(NCc3c(F)cccc3C(F)(F)F)nc(NCc3cn[nH]c3)nc12 CHEMBL4225801 IC50 450.0 nM
c1cn(-c2ccc(Nc3ncnc4ccc(-c5cncs5)cc34)cc2)cn1 CHEMBL3426086 IC50 460.0 nM
O=C(O)[C@H]1CC[C@H](Nc2ncnc3ccc(-c4cncs4)cc23)CC1 CHEMBL3426043 IC50 498.0 nM
Cc1cc(NCc2c(F)cccc2C(F)(F)F)c2cccc(C(N)=O)c2n1 CHEMBL3604734 IC50 510.0 nM
COCCO[C@H]1CC[C@H](NC(=O)c2nc(-c3cncs3)cc3cc[nH]c23)CC1 CHEMBL5170495 IC50 511.0 nM
NC(=O)c1ccc(Nc2ncnc3ccc(-c4cncs4)cc23)cc1 CHEMBL3426084 IC50 560.0 nM
Cc1cc(NCc2cccc(Cl)c2Cl)c2cccc(C(N)=O)c2n1 CHEMBL3604717 IC50 620.0 nM
Cc1n[nH]cc1CNc1nc(NCc2c(F)cccc2C(F)(F)F)c2cccc(C(N)=O)c2n1 CHEMBL4228591 IC50 620.0 nM
NC(=O)c1cccc2c(NCc3c(F)cccc3C(F)(F)F)nc(N3CCc4[nH]ncc4C3)nc12 CHEMBL4226457 IC50 630.0 nM
NS(=O)(=O)c1ccc(Nc2ncnc3ccc(-c4cncs4)cc23)cc1 CHEMBL3426081 IC50 700.0 nM
Clc1cccc(Nc2ncnc3ccc(-c4cncs4)cc23)c1 CHEMBL3426072 IC50 700.0 nM
COc1ccccc1NC(=O)c1ccnc(-n2ccnc2)n1 CHEMBL5415574 IC50 700.0 nM
COCCO[C@H]1C[C@H](NC(=O)c2cc(-c3cncs3)cc3[nH]ccc23)C1 CHEMBL5207454 IC50 761.0 nM
CO[C@H]1CC[C@H](NC(=O)c2cc(-n3ccnc3)cc3[nH]cnc23)CC1 CHEMBL5421625 IC50 770.0 nM
Cc1cc(NCc2c(F)cccc2Cl)c2cccc(C(N)=O)c2n1 CHEMBL3604732 IC50 780.0 nM
c1nc(Nc2ccc(-c3cnco3)cc2)c2cc(-c3cncs3)ccc2n1 CHEMBL3426085 IC50 840.0 nM
c1ccc(Nc2ncnc3ccc(-c4cncs4)cc23)cc1 CHEMBL3426069 IC50 840.0 nM
c1cc(Nc2ncnc3ccc(-c4cncs4)cc23)ccn1 CHEMBL3426090 IC50 950.0 nM
CS(=O)(=O)[C@H]1CC[C@H](Nc2ncnc3ccc(-c4cncs4)cc23)CC1 CHEMBL3426044 IC50 959.0 nM
CS(=O)(=O)Nc1ccc(Nc2ncnc3ccc(-c4cncs4)cc23)cc1 CHEMBL3426082 IC50 970.0 nM
Fc1cccc(Nc2ncnc3ccc(-c4cncs4)cc23)c1 CHEMBL3426075 IC50 970.0 nM
NC(=O)[C@@H]1CCC[C@@H](Nc2ncnc3ccc(-c4cncs4)cc23)C1 CHEMBL3426192 IC50 971.0 nM
Cc1cc(NCc2c(Cl)cccc2Cl)c2cccc(C(N)=O)c2n1 CHEMBL3604722 IC50 990.0 nM