O=C(O)COc1c2cccc1Sc1cccc(c1OCC(=O)O)Sc1cccc(c1OCC(=O)O)Sc1cccc(c1OCC(=O)O)S2 CHEMBL591694 Kd 0.32 nM
CCCOc1c2cc(NC(=S)N[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3NC(C)=O)cc1Cc1cc(NC(=S)N[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3NC(C)=O)cc(c1OCCC)Cc1cc(NC(=S)N[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3NC(C)=O)cc(c1OCCC)Cc1cc(NC(=S)N[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3NC(C)=O)cc(c1OCCC)C2 CHEMBL601098 pIC50 0.5012 nM
CC(=O)N[C@@H]1[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)O[C@H]1O CHEMBL1222111 Kd 1.12 nM
CC(C)(C)c1cc2c(OCC(=O)O)c(c1)Cc1cc(C(C)(C)C)cc(c1OCC(=O)O)Cc1cc(C(C)(C)C)cc(c1OCC(=O)O)Cc1cc(C(C)(C)C)cc(c1OCC(=O)O)C2 CHEMBL601099 Kd 3.0 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CCCC[C@H]4NC(=O)c3noc(C(C)(C)C)n3)n2)cn1 CHEMBL5080861 IC50 10.0 nM
O=C(O)COc1cc2cc(c1)Cc1cccc(c1OCC(=O)O)Cc1cc(cc(OCC(=O)O)c1)Cc1cccc(c1OCC(=O)O)C2 CHEMBL601100 IC50 14.0 nM
C[C@@H]1CN(C2COC2)CCN1c1ccc(Nc2cc(-c3ccnc(N4CCn5c(cc6c5CC(C)(C)C6)C4=O)c3CO)cn(C)c2=O)nc1 CHEMBL4066176 IC50 40.0 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CCCCC4NC(=O)N3CC[C@@H](C(C)(C)C)C3)n2)cn1 CHEMBL5088454 IC50 40.0 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CCCC[C@H]4NC(=O)c3nc(C(C)(C)C)no3)n2)cn1 CHEMBL5076817 IC50 59.0 nM
O=C(O)c1ccc(/N=N/c2cc3c(O)c(c2)Cc2cc(/N=N/c4ccc(C(=O)O)cc4)cc(c2O)Cc2cc(/N=N/c4ccc(C(=O)O)cc4)cc(c2O)Cc2cc(/N=N/c4ccc(C(=O)O)cc4)cc(c2O)C3)cc1 CHEMBL591636 pIC50 63.1 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CN(C3COC3)CC[C@H]4NC(=O)c3cn(C(C)(C)C)nn3)n2)cn1 CHEMBL5083772 IC50 70.0 nM
O=C(O)COc1c2cccc1Sc1cccc(c1O)Sc1cccc(c1OCC(=O)O)Sc1cccc(c1O)S2 CHEMBL596977 pIC50 79.43 nM
O=C1[C@H](Nc2cc(F)cc(Cl)c2)CCCN1[C@@H]1CCCN(c2ncnc3[nH]ncc23)C1 CHEMBL5206309 IC50 90.0 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CN(CC(F)(F)F)CC[C@H]4NC(=O)c3cn(C(C)(C)C)nn3)n2)cn1 CHEMBL5085192 IC50 100.0 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CCCC[C@H]4NC(=O)c3cn(C(C)(C)C)nn3)n2)cn1 CHEMBL5085931 IC50 104.0 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CCCCC4NC(=O)c3noc(C(C)(C)C)n3)n2)cn1 CHEMBL5083323 IC50 130.0 nM
C=CC(=O)N1CCC[C@@H](n2c(=O)n(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccc32)C1 CHEMBL4650323 IC50 200.0 nM
CN1CC[C@@H](NC(=O)c2cn(C(C)(C)C)nn2)c2ccc(-c3ccnc(Nc4cnn(C)c4)n3)cc2C1 CHEMBL5094998 IC50 200.0 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CCCCC4NC(=O)c3nc(C(C)(C)C)no3)n2)cn1 CHEMBL5084997 IC50 220.0 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CCCC[C@H]4NC(=O)c3nnc(C(C)(C)C)o3)n2)cn1 CHEMBL5089327 IC50 330.0 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CCCCC4NC(=O)c3nnc(C(C)(C)C)o3)n2)cn1 CHEMBL5090589 IC50 390.0 nM
CC(C)OC1CN(C(=O)N[C@@H]2CCCCc3cc(-c4ccnc(Nc5cnn(C)c5)n4)ccc32)C1 CHEMBL5090290 IC50 400.0 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CCNC[C@H]4NC(=O)c3cn(C(C)(C)C)nn3)n2)cn1 CHEMBL5081318 IC50 400.0 nM
O=C1[C@H](Nc2cc(F)cc(Cl)c2)CCCN1[C@@H]1CCCN(c2ncnc3[nH]ccc23)C1 CHEMBL5169765 IC50 630.0 nM
CN1CCc2cc(-c3ccnc(Nc4cnn(C)c4)n3)ccc2[C@H](NC(=O)c2cn(C(C)(C)C)nn2)C1 CHEMBL5073995 IC50 700.0 nM
COCCN1CC[C@@H](NC(=O)c2cn(C(C)(C)C)nn2)c2ccc(-c3ccnc(Nc4cnn(C)c4)n3)cc2C1 CHEMBL5093189 IC50 800.0 nM
Cn1cc(Nc2nccc(-c3ccc4c(c3)CCCCC4NC(=O)c3cn(C(C)(C)C)nn3)n2)cn1 CHEMBL5087011 IC50 860.0 nM
C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3)nc3ccoc23)c1 CHEMBL4163691 IC50 980.0 nM