C[C@@]1(O)CCC[C@H]1n1c(=O)c(C(F)F)cc2cnc(NC3CCN(S(C)(=O)=O)CC3)nc21 CHEMBL4446357 Ki 0.09 nM
CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 IC50 0.1 nM
O=[N+]([O-])c1cccc(Nc2nccc(-c3cnn4ncccc34)n2)c1 CHEMBL526110 IC50 0.3 nM
NS(=O)(=O)c1ccc(Nc2cc(-c3ccc([N+](=O)[O-])cc3)[nH]n2)cc1 CHEMBL317703 IC50 0.33 nM
Nc1ccc(-c2cc(Nc3ccc(S(N)(=O)=O)cc3)[nH]n2)cc1 CHEMBL321517 IC50 0.34 nM
CC(=O)NC1CN(c2ccc(Nc3ncc(F)c(-c4cnc(C)n4C(C)C)n3)cc2)C1 CHEMBL476577 IC50 0.5 nM
COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(S(C)(=O)=O)CC2)nc1N CHEMBL384304 Kd 0.53 nM
O=C1Nc2ccc3ncsc3c2/C1=C/Nc1ccc(S(=O)(=O)NCCOCCO)cc1 CHEMBL1964259 IC50 0.54 nM
CC[C@H](CO)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1 CHEMBL14762 IC50 0.7 nM
CC[C@@H](C)Oc1nc(Nc2ccc(S(N)(=O)=O)cc2)nc(N)c1C=O CHEMBL4088242 IC50 0.8 nM
O=C1NCC2(CCCCC2)n2c1cc1cnc(Nc3ccc(N4CCC(N5CCOCC5)CC4)cn3)nc12 CHEMBL3919361 IC50 0.857 nM
CN1CC[C@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@H](O)C1 CHEMBL428690 Cell cycle 1.0 nM
COCCOCCOCCOCCN(C)S(=O)(=O)c1ccc(N/C=C2\C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL1964249 IC50 1.0 nM
N#Cc1ccc(Nc2nccc(-c3cnn4ncccc34)n2)cc1 CHEMBL359794 Ki 1.0 nM
Clc1ccc(Nc2nccc(-c3cnn4ncccc34)n2)cc1Cl CHEMBL186890 Ki 1.0 nM
Fc1cc(F)cc(Nc2nccc(-c3cnn4ncccc34)n2)c1 CHEMBL184510 Ki 1.0 nM
COCCNS(=O)(=O)c1ccc(Nc2nccc(-c3cnc(C)n3C(C)C)n2)cc1 CHEMBL478409 IC50 1.0 nM
Cc1ncc(-c2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)c(F)c3)ncc2F)n1C(C)C CHEMBL509406 IC50 1.0 nM
CN1CCN(c2cccc(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 CHEMBL559513 IC50 1.0 nM
NCCCn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3)ncc1CC2 CHEMBL1171950 IC50 1.0 nM
Cc1nc2ccccn2c1-c1ccnc(Nc2ccc(OCC(O)CN(C)C)cc2)n1 CHEMBL102926 IC50 1.0 nM
NS(=O)(=O)c1ccc(Nc2nccc(-c3cnc4ccccn34)n2)cc1 CHEMBL73303 IC50 1.0 nM
CCc1cnn2c(NCc3ccc[n+]([O-])c3)cc(N3CCCC[C@H]3CCO)nc12 CHEMBL2103840 IC50 1.0 nM
Cc1cnn2c(NCc3ccc[n+]([O-])c3)cc(N3CCCC[C@@H]3CCO)nc12 CHEMBL4292930 IC50 1.0 nM
CCc1cnn2c(NCc3ccc[n+]([O-])c3)cc(C3CCCC[C@H]3CCO)nc12 CHEMBL5171657 IC50 1.0 nM
CCc1cnn2c(NCc3ccc[n+]([O-])c3)cc(N3CCCC[C@@H]3CCO)nc12 CHEMBL5266005 IC50 1.0 nM
O=C1NCC2(CCCCC2)n2c1cc1cnc(Nc3ccc(N4CCNCC4)cn3)nc12 CHEMBL3890528 IC50 1.08 nM
Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nc(OCC2CCCCC2)c1N=O CHEMBL318999 IC50 1.1 nM
CC(C)Cc1cccc2c1/C(=N/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL411224 IC50 1.2 nM
Cn1cc(Nc2ncc(Cl)c(Nc3ccccc3C(N)=O)n2)cn1 CHEMBL1984548 pKi 1.259 nM
CC(C)=Cc1cccc2c1/C(=N/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL270544 IC50 1.5 nM
NS(=O)(=O)c1ccc(N/C=C2\C(=O)Nc3ccc4ncccc4c32)cc1 CHEMBL445945 IC50 1.5 nM
CC(C)N1CCN(c2ccc(Nc3ncc4cc5n(c4n3)C3(CCCCC3)CNC5=O)nc2)CC1 CHEMBL3904602 IC50 1.51 nM
Cn1cc(Nc2ncc(Br)c(Nc3ccccc3C(N)=O)n2)cn1 CHEMBL1994669 pKi 1.585 nM
NS(=O)(=O)c1ccc(N/N=C2\C(=O)Nc3ccc4ncccc4c32)cc1 CHEMBL409892 IC50 1.6 nM
CN1CCN(c2ccc(Nc3ncc4cc5n(c4n3)C3(CCCCC3)CNC5=O)nc2)CC1 CHEMBL3894860 IC50 1.66 nM
COc1cccc(OC)c1CNC(=O)c1ccc2c(c1)/C(=N/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL271136 IC50 1.7 nM
CC(C)CC(=O)c1ccc2c(c1)/C(=C/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL429142 IC50 1.9 nM
COc1cccc(Nc2nccc(-c3cnn4ncccc34)n2)c1 CHEMBL187081 pIC50 1.995 nM
Fc1ccc(Nc2nccc(-c3cnn4ncccc34)n2)cc1F CHEMBL364370 pIC50 1.995 nM
O=C(Nc1n[nH]c2nc(-c3ccc(O)c(Br)c3)ccc12)C1CC1 CHEMBL260416 IC50 2.0 nM
O=C(Nc1n[nH]c2nc(-c3ccc(O)c(Cl)c3)ccc12)C1CC1 CHEMBL259838 IC50 2.0 nM
CCc1cnc(CSc2cnc(NC(C)=O)s2)o1 CHEMBL125401 Cell cycle 2.0 nM
CCc1cnc(CSc2cnc(NC(=O)Cc3cccnc3)s2)o1 CHEMBL129396 Cell cycle 2.0 nM
Cc1nc(N)sc1-c1ccnc(Nc2cccc([N+](=O)[O-])c2)n1 CHEMBL298445 Ki 2.0 nM
C/C(Nc1ccc(S(N)(=O)=O)cc1)=C1/C(=O)Nc2ccc(-c3cnco3)cc21 CHEMBL411887 IC50 2.0 nM
CN(C)S(=O)(=O)c1ccc(Nc2cc(N[C@H]3CC[C@H](N)CC3)nc3c(Br)cnn23)cc1Cl CHEMBL178769 IC50 2.0 nM
Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nn1C(=O)c1c(F)cccc1F CHEMBL191003 IC50 2.0 nM
COc1cc(F)c(F)c(F)c1C(=O)c1cnc(NC2CCN(S(C)(=O)=O)CC2)nc1N CHEMBL213713 Ki 2.0 nM
N#Cc1cccc(Nc2nccc(-c3cnn4ncccc34)n2)c1 CHEMBL495696 IC50 2.0 nM
C[C@H](C(=O)Nc1cc(C2CC2)[nH]n1)c1ccc(N2Cc3ccccc3C2=O)cc1 CHEMBL190446 IC50 2.0 nM
C[C@H](C(=O)Nc1cc(C2CC2)[nH]n1)c1ccc(N2CCNC2=O)cc1 CHEMBL192602 IC50 2.0 nM
Cc1ncc(-c2ccnc(Nc3ccc(C(=O)NCCO)cc3)n2)n1C(C)C CHEMBL487067 IC50 2.0 nM
CNC(=O)c1ccc(Nc2nccc(-c3cnc(C)n3C3CCCC3)n2)cc1 CHEMBL488257 IC50 2.0 nM
Cc1ncc(-c2nc(Nc3ccc(C(=O)N(C)C)cc3)ncc2F)n1C(C)C CHEMBL453862 IC50 2.0 nM
Cc1ncc(-c2nc(Nc3ccc(C(=O)N(C)C)c(F)c3)ncc2F)n1C(C)C CHEMBL454648 IC50 2.0 nM
Cc1ncc(-c2nc(Nc3ccc(C(=O)NCCN(C)C)c(F)c3)ncc2F)n1C(C)C CHEMBL462385 IC50 2.0 nM
Cc1ncc(-c2nc(Nc3ccc(C(=O)N4CC[C@H](N(C)C)C4)cc3)ncc2F)n1C(C)C CHEMBL460102 IC50 2.0 nM
Cc1ncc(-c2nc(Nc3ccc(C(=O)N4CCCN(C)CC4)cc3)ncc2F)n1C(C)C CHEMBL462192 IC50 2.0 nM
CN[C@H]1CCN(C(=O)c2ccc(Nc3nccc(-c4cnc(C)n4C(C)C)n3)cc2)C1 CHEMBL460087 IC50 2.0 nM
CN[C@H]1CCN(C(=O)c2ccc(Nc3ncc(F)c(-c4cnc(C)n4C(C)C)n3)cc2)C1 CHEMBL455657 IC50 2.0 nM
Cn1nc(C(N)=O)c2c1-c1nc(Nc3ccccc3)ncc1CC2 CHEMBL559845 IC50 2.0 nM
CN1CCN(c2ccc(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)cc2)CC1 CHEMBL560817 IC50 2.0 nM
FC(F)(F)c1cnc(Nc2ccc3[nH]cnc3c2)nc1Nc1ccccc1Cl CHEMBL194721 IC50 2.0 nM
CC[C@@H](NC(=O)N1CCc2cnc(NC3CCOCC3)nc2C1)c1ccc(C#N)c(Cl)c1 CHEMBL3298985 IC50 2.0 nM
C[C@@H](NC(=O)N1CCc2cnc(N[C@H]3CCO[C@@H](CO)C3)nc2C1)c1ccc(Cl)c(Cl)c1 CHEMBL3298199 IC50 2.0 nM
COc1cc(Nc2ncc(Br)c(N[C@H](C)C(C)(C)O)n2)ccc1S(C)(=N)=O CHEMBL3648115 IC50 2.0 nM
C[C@H](Nc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br)C(C)(C)O CHEMBL3648116 IC50 2.0 nM
C[C@H](O)[C@@H](C)Nc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br CHEMBL3648117 IC50 2.0 nM
O=C1Nc2ccc([N+](=O)[O-])cc2/C1=C1/Nc2ccc(O)cc2/C1=N\O CHEMBL4457608 IC50 2.0 nM
COc1cc[nH]c1/C=C1\C(=O)Nc2ccc(F)c(C#C[C@@H]3CCCN3)c21 CHEMBL355631 IC50 2.0 nM
COC(=O)c1ccc2c(c1)/C(=C/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL409731 IC50 2.1 nM
NS(=O)(=O)c1ccc(N/N=C2\C(=O)Nc3ccc(C(=O)NCc4cccnc4)cc32)cc1 CHEMBL271953 IC50 2.1 nM
NS(=O)(=O)c1ccc(N/N=C2\C(=O)Nc3ccc4[nH]nc(Cl)c4c32)cc1 CHEMBL269882 IC50 2.2 nM
Cn1cc(-c2cnc3c(-c4csc(C(=O)N[C@@H]5CCCC[C@@H]5N)c4)cnn3c2)cn1 CHEMBL4568087 IC50 2.2 nM
NS(=O)(=O)c1ccc(N/N=C2\C(=O)Nc3ccc(-c4cnco4)cc32)cc1 CHEMBL269827 IC50 2.3 nM
CN1CCN(Cc2ccc(NC(=O)c3n[nH]cc3Nc3ncnc4[nH]ccc34)cc2)CC1 CHEMBL4077071 IC50 2.47 nM
CC(C)c1cccc2c1/C(=N/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL411426 IC50 2.5 nM
NS(=O)(=O)c1ccc(N/C=C2\C(=O)Nc3ccc(-c4cnco4)cc32)cc1 CHEMBL270132 IC50 2.5 nM
NS(=O)(=O)c1ccc(NC=C2C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL1794055 IC50 2.8 nM
NS(=O)(=O)c1ccc(N/C=C2\C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL271595 IC50 2.8 nM
O=C(Cc1ccc(Cc2cccs2)cc1)Nc1cc(C2CC2)[nH]n1 CHEMBL490481 pIC50 2.999 nM
NCCSc1cc(-c2ccc[nH]2)c2c3c(ccc(F)c13)NC2=O CHEMBL311464 IC50 3.0 nM
CC(C)COC(=O)c1ccc2c(c1)/C(=C/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL269883 IC50 3.0 nM
Cc1cc(C)cc(Nc2nccc(-c3cnn4ncccc34)n2)c1 CHEMBL186101 Ki 3.0 nM
O=[N+]([O-])c1ccc(Nc2nccc(-c3cnn4ncccc34)n2)cc1 CHEMBL188938 IC50 3.0 nM
c1cc(Nc2nccc(-c3cnn4ncccc34)n2)cc(-c2cocn2)c1 CHEMBL497564 IC50 3.0 nM
Cc1ncc(-c2ccnc(Nc3ccc(F)cc3)n2)n1C(C)C CHEMBL478407 IC50 3.0 nM
Cc1ncc(-c2ccnc(Nc3ccc(N4CCN(S(=O)(=O)CCN(C)C)CC4)cc3)n2)n1C(C)C CHEMBL477785 IC50 3.0 nM
O=C(Nc1ccc(F)cc1)c1n[nH]cc1NC(=O)c1c(F)cccc1F CHEMBL518383 IC50 3.0 nM
Cc1ncc(-c2ccnc(Nc3ccc(C(N)=O)cc3)n2)n1C(C)C CHEMBL488084 IC50 3.0 nM
CNC(=O)c1ccc(Nc2nccc(-c3cnc(C)n3C(C)C)n2)cc1 CHEMBL508129 IC50 3.0 nM
CNC(=O)c1ccc(Nc2ncc(F)c(-c3cnc(C)n3C(C)C)n2)cc1 CHEMBL453655 IC50 3.0 nM
Cc1ncc(-c2ccnc(Nc3ccc(C(=O)NCCN(C)C)c(F)c3)n2)n1C(C)C CHEMBL453629 IC50 3.0 nM
CCC1CC(C(=O)Nc2ncc(SCc3ncc(C(C)(C)C)o3)s2)CCN1 CHEMBL455195 IC50 3.0 nM
N[C@H]1CC[C@H](Nc2cc(Nc3ccc(F)c(Cl)c3)n3ncc(Cl)c3n2)CC1 CHEMBL2163996 IC50 3.0 nM
C[C@H](O)[C@@H](C)Nc1nc(Nc2ccc(S(=N)(=O)CCO)cc2)ncc1Br CHEMBL3648110 IC50 3.0 nM
COc1cc(Nc2ncc(Br)c(N[C@H](C)[C@H](C)O)n2)ccc1S(C)(=N)=O CHEMBL3648112 IC50 3.0 nM
C[C@@H](O)[C@@H](C)Nc1nc(Nc2ccc(S(=N)(=O)CCO)cc2)ncc1Br CHEMBL3648109 IC50 3.0 nM
CN1C/C=C/CCOc2cccc(c2)-c2ccnc(n2)Nc2cccc(c2)C1 CHEMBL1944698 IC50 3.0 nM
Clc1ccccc1-c1cc(NCc2cccnc2)n2ncc(Br)c2n1 CHEMBL401303 IC50 3.0 nM
C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(S(=O)(=O)CCO)cc2)ncc1C(F)(F)F CHEMBL3644026 IC50 3.0 nM
COc1cc[nH]c1/C=C1\C(=O)Nc2ccc(F)c(C#C[C@@H](O)[C@@H](N)[C@@H](C)O)c21 CHEMBL354634 IC50 3.0 nM
CC(C)c1cnn2c(NCc3ccccc3)cc(N[C@@H](CO)[C@H](O)CO)nc12 CHEMBL1234833 IC50 3.0 nM
CC(C)c1cnn2c(NCc3ccccc3)cc(N[C@@H](CO)[C@@H](O)CO)nc12 CHEMBL4644434 IC50 3.0 nM
COCCN1CCN(Cc2ccc(-c3n[nH]c4c3C(=O)c3c(NC(=O)NN5CCOCC5)cccc3-4)cc2)CC1 CHEMBL3545083 IC50 3.0 nM
CCCC(=O)Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12 CHEMBL1977223 pKi 3.162 nM
N=C(N)NS(=O)(=O)c1ccc(N/C=C2\C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL1964255 IC50 3.3 nM
CC(C)Oc1cccc2c1/C(=N/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL271160 IC50 3.4 nM
C[C@@H]1C[C@H]2CN1CCn1nc3c(cccc3c1O)-c1nc3c(cccc3nc1O)O2 CHEMBL215803 IC50 3.4 nM
CN(C)C[C@@H](NC(=O)c1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1)c1ccccc1 CHEMBL2064555 Ki 3.4 nM
N[C@H]1CC[C@H](Nc2cc(Nc3ccc(F)c(Cl)c3)n3ncc(Br)c3n2)CC1 CHEMBL2163995 IC50 3.4 nM
O=C1Nc2ccc3ncsc3c2/C1=C/Nc1ccc(S(=O)(=O)NCCc2c[nH]cn2)cc1 CHEMBL1964251 IC50 3.6 nM
c1cnc2[nH]cc(-c3ccnc(NCC4CCCCC4)n3)c2c1 CHEMBL213207 pKi 3.981 nM
Cc1ccccc1-c1c(-c2ccc3[nH]nc(C)c3c2)nnn1Cc1ccccc1 CHEMBL1983315 pKi 3.981 nM
O=C(Cc1ccc(-c2ccccc2)c(F)c1)Nc1cc(C2CC2)[nH]n1 CHEMBL489477 pIC50 3.999 nM
CNS(=O)(=O)c1ccc2c(c1)/C(=C/c1[nH]cc3c1CCOC3=O)C(=O)N2 CHEMBL60541 IC50 4.0 nM
O=C1Nc2ccc(C(=O)O)cc2/C1=C/c1[nH]cc2c1CCOC2=O CHEMBL293068 IC50 4.0 nM
COCCCNS(=O)(=O)c1ccc(Nc2nccc(-c3cnc4ccccn34)n2)cc1 CHEMBL73243 IC50 4.0 nM
CC(C)[C@H](CO)Nc1nc(Nc2cccc(Cl)c2)c2ncn(C(C)C)c2n1 CHEMBL23327 IC50 4.0 nM
CN(C)S(=O)(=O)c1ccc(Nc2cc(N[C@H]3CC[C@H](N)CC3)nc3c(C4CCCC4)cnn23)cc1 CHEMBL178179 IC50 4.0 nM
CN1CCN(c2ccc(Nc3nccc(-c4cnn5ncccc45)n3)cc2C(F)(F)F)CC1 CHEMBL468963 IC50 4.0 nM
CCn1c(-c2ccnc(Nc3ccc(S(=O)(=O)NCCOC)cc3)n2)cnc1C CHEMBL485618 IC50 4.0 nM
CCCN(C)[C@H]1CCN(C(=O)c2ccc(Nc3nccc(-c4cnc(C)n4C(C)C)n3)cc2)C1 CHEMBL518826 IC50 4.0 nM
N#Cc1cnn2c(Nc3ccc(F)c(Cl)c3)cc(N[C@H]3CC[C@H](N)CC3)nc12 CHEMBL2163997 IC50 4.0 nM
C[C@@H](NC(=O)N1CCc2cnc(Nc3cnn(C)c3)nc2C1)c1ccc(Cl)c(Cl)c1 CHEMBL3357950 IC50 4.0 nM
CCS(=N)(=O)c1ccc(Nc2ncc(Br)c(N[C@H](C)[C@H](C)O)n2)cc1 CHEMBL3648095 IC50 4.0 nM
COC[C@@H](Nc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br)[C@@H](C)O CHEMBL3648118 IC50 4.0 nM
CCS(=N)(=O)c1ccc(Nc2ncc(Br)c(N[C@@H](C)[C@H](C)O)n2)cc1 CHEMBL3648122 IC50 4.0 nM
Cc1cc(Nc2ncc(Br)c(N[C@H](C)[C@H](C)O)n2)ccc1S(C)(=N)=O CHEMBL3648096 IC50 4.0 nM
C[C@H](Nc1nc(Nc2ccc(S(=N)(=O)CCO)cc2)ncc1Br)C(C)(C)O CHEMBL3648108 IC50 4.0 nM
Cc1cc(Nc2ncc(Br)c(N[C@H](C)C(C)(C)O)n2)ccc1S(C)(=N)=O CHEMBL3639469 IC50 4.0 nM
COc1cc(Nc2ncc(Br)c(N[C@H](C)[C@@H](C)O)n2)ccc1S(C)(=N)=O CHEMBL3648111 IC50 4.0 nM
C[C@@H](Nc1nc(Nc2ccc(S(=N)(=O)CCO)cc2)ncc1Br)C(C)(C)O CHEMBL3648107 IC50 4.0 nM
C[C@@H](Nc1nc(Nc2ccc(S(=N)(=O)CC3CC3)cc2)ncc1Br)C(C)(C)O CHEMBL3648076 IC50 4.0 nM
CN=S(C)(=O)c1ccc(Nc2ncc(Br)c(N[C@H](C)[C@@H](C)O)n2)cc1OC CHEMBL3648113 IC50 4.0 nM
CC(CO)Sc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br CHEMBL3648106 IC50 4.0 nM
C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(S(C)(=O)=O)cc2)ncc1C(F)(F)F CHEMBL3644033 IC50 4.0 nM
C[C@H](CO)Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)ncc1Br CHEMBL4741442 IC50 4.0 nM
NC(=O)c1ccc(Nc2nc(N[C@H]3CC[C@H](N)CC3)nc3c2ncn3C2CCCC2)cc1 CHEMBL5188322 IC50 4.0 nM
C[C@H](CO)Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)ncc1Br CHEMBL4764656 IC50 4.0 nM
COc1cc(-c2ccc3c(-c4nc5c(N6CCN(C)CC6)cccc5[nH]4)n[nH]c3c2)ccc1O CHEMBL514197 IC50 4.1 nM
O=C1Nc2ccc3ncsc3c2/C1=C/Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1 CHEMBL1964244 IC50 4.3 nM
NC(=O)c1ccc2c(c1)/C(=N/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL410883 IC50 4.5 nM
COCCOCCOCCOCCNS(=O)(=O)c1ccc(N/C=C2\C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL1964250 IC50 4.5 nM
CN(C)S(=O)(=O)c1ccc(N/C=C2\C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL1964247 IC50 4.6 nM
Cc1c([N+](=O)[O-])ccc2c1/C(=N/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL272667 IC50 4.6 nM
NS(=O)(=O)c1ccc(/N=N/c2c(O)[nH]c3cccc(I)c23)cc1 CHEMBL314397 IC50 4.6 nM
O=C1Nc2ccc3ncsc3c2/C1=C/Nc1ccc(S(=O)(=O)NCCO)cc1 CHEMBL1964246 IC50 4.7 nM
NS(=O)(=O)c1ccc(Nc2ncc3c(n2)N(C2CCCC2)C(=O)C32CC2)cc1 CHEMBL5186159 IC50 4.9 nM
O=C(Nc1n[nH]c2cc(-c3ccc(O)cc3)ccc12)C1CC1 CHEMBL260163 IC50 5.0 nM
O=C(Nc1n[nH]c2nc(-c3ccc(O)cc3)c(-c3ccccc3)cc12)C1CC1 CHEMBL427909 IC50 5.0 nM
O=C(Nc1n[nH]c2nc(-c3ccc(O)cc3)c(Br)cc12)C1CC1 CHEMBL260417 IC50 5.0 nM
O=C1Nc2ccc(F)c3c(S[C@H]4CCNC4)cc(-c4ccc[nH]4)c1c23 CHEMBL79498 IC50 5.0 nM
N#CCCc1cc(-c2ccc[nH]2)c2c3c(ccc(F)c13)NC2=O CHEMBL415471 IC50 5.0 nM
O=C(Nc1n[nH]c2nnc(-c3cccnc3)cc12)C1CC1 CHEMBL35785 cKi 5.0 nM
CN(C)CCNS(=O)(=O)c1ccc(Nc2nccc(-c3cnc4ccccn34)n2)cc1 CHEMBL72548 IC50 5.0 nM
O=C(Nc1n[nH]c2nnc(-c3cccc(F)c3F)cc12)C1CCCC1 CHEMBL287092 cKi 5.0 nM
CN(C)CCCN(C)S(=O)(=O)c1ccc(Nc2nccc(-c3cnc4ccccn34)n2)cc1 CHEMBL70824 IC50 5.0 nM
Clc1cccc(Nc2nccc(-c3cnc4ccccn34)n2)c1 CHEMBL72509 IC50 5.0 nM
c1ccc(Nc2nccc(-c3cnn4ncccc34)n2)cc1 CHEMBL359554 Ki 5.0 nM
O=C(NC1=NNC2=CC=CC21)C1CC1 CHEMBL500804 IC50 5.0 nM
O=C(NC1CC1)c1n[nH]c2cc(-c3ccc(O)cc3)c(Br)cc12 CHEMBL481562 IC50 5.0 nM
C[C@H]1CNC[C@H](C(=O)Nc2ncc(SCc3ncc(C(C)(C)C)o3)s2)C1 CHEMBL452601 IC50 5.0 nM
CN(C)CCNS(=O)(=O)c1ccc(Nc2cccc(-c3cnc4ccccn34)c2)cc1 CHEMBL1241849 IC50 5.0 nM
CC(C)(C)n1nc(Cc2cccc3ccccc23)c2c(N)ncnc21 CHEMBL573578 IC50 5.0 nM
COC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cc(C(=O)O)c2cc(/C=C/c3ccc(Cl)cc3)ccc2n1 CHEMBL3099763 Kd 5.0 nM
COC1CCN(c2nccc(Nc3cc4[nH]c(-c5cn[nH]c5)cc4cn3)n2)CC1 CHEMBL3354186 IC50 5.0 nM
CCS(=N)(=O)c1ccc(Nc2ncc(Br)c(N[C@H](C)C(C)(C)O)n2)cc1 CHEMBL3648123 IC50 5.0 nM
NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3nc[nH]c3n2)cc1 CHEMBL319467 IC50 5.0 nM
Cc1cc(C)c(CNc2nc(N[C@@H](C)[C@@H](C)O)nc3c2ncn3C(C)C)cn1 CHEMBL4579344 IC50 5.0 nM
CC[C@H](Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1)[C@@H](C)O CHEMBL4764173 IC50 5.0 nM
C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(S(=N)(=O)C3CC3)cc2)ncc1C(F)(F)F CHEMBL4442620 IC50 5.0 nM
CC[C@@H](Nc1nc(NCc2cnc(C)cc2C)c2ncn(C(C)C)c2n1)[C@H](C)O CHEMBL5195030 IC50 5.0 nM
CC[C@H](Nc1nc(NCc2cnc(C)cc2C)c2ncn(C(C)C)c2n1)[C@@H](C)O CHEMBL3655762 IC50 5.0 nM
c1ccc(Cn2cc(-c3ccc4[nH]nc(-c5cn(Cc6ccccc6)nn5)c4c3)nn2)cc1 CHEMBL1964288 pKi 5.012 nM
FC(F)(F)c1ccccc1CNc1nccc(-c2c[nH]c3ncccc23)n1 CHEMBL1999153 pKi 5.012 nM
O=C1Nc2ccc3ncsc3c2/C1=C/Nc1ccc(S(=O)(=O)NCc2ccccc2)cc1 CHEMBL1964242 IC50 5.6 nM
CNS(=O)(=O)c1ccc(N/C=C2\C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL1964245 IC50 5.6 nM
CN(c1ccccn1)S(=O)(=O)c1ccc(N/C=C2\C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL1964253 IC50 5.6 nM
CNS(=O)(=O)Cc1ccc(N/N=C2\C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL1234086 IC50 5.7 nM
CS(=O)(=O)c1ccc(N/C=C2\C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL1964260 IC50 5.7 nM
Cc1ccc(F)c(Nc2ccnc(Nc3ccc(S(N)(=O)=O)cc3)n2)c1 CHEMBL103355 IC50 6.0 nM
c1cnn2ncc(-c3ccnc(Nc4ccc5c(c4)OCCO5)n3)c2c1 CHEMBL361894 Ki 6.0 nM
c1cnn2ncc(-c3ccnc(Nc4ccc5c(c4)OCCCO5)n3)c2c1 CHEMBL186708 Ki 6.0 nM
Cc1ccc2c(-c3ccnc(Nc4ccc5c(c4)OCCO5)n3)cnn2n1 CHEMBL434337 Ki 6.0 nM
COc1cc(F)c(F)cc1C(=O)c1cnc(NC2CCN(S(C)(=O)=O)CC2)nc1N CHEMBL215086 Ki 6.0 nM
CC(C)[C@H](CO)Nc1nc(Nc2ccc(C(=O)O)c(Cl)c2)c2ncn(C(C)C)c2n1 CHEMBL23254 IC50 6.0 nM
Cc1ncc(-c2ccnc(Nc3ccc(S(=O)(=O)NCCCOC(C)C)cc3)n2)n1C CHEMBL520353 IC50 6.0 nM
Cc1ncc(-c2ccnc(Nc3ccc(S(C)(=O)=O)cc3)n2)n1C(C)C CHEMBL488436 IC50 6.0 nM
Cc1ncc(-c2nc(Nc3ccc(N4CCN(C(=O)CO)CC4)cc3)ncc2F)n1C(C)C CHEMBL476993 IC50 6.0 nM
Cc1ncc(-c2ccnc(Nc3ccc(C(=O)N(C)C)c(F)c3)n2)n1C(C)C CHEMBL510436 IC50 6.0 nM
Cc1ncc(-c2nc(Nc3ccc(C(=O)N4CC[C@@H](N(C)C)C4)cc3)ncc2F)n1C(C)C CHEMBL460103 IC50 6.0 nM
CCCCOc1c(C(=O)c2c(F)cc(C)cc2F)ccc2[nH]ncc12 CHEMBL1241567 IC50 6.0 nM
C[C@@H](Nc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br)C(C)(C)O CHEMBL3648072 IC50 6.0 nM
CN=S(C)(=O)c1ccc(Nc2ncc(Br)c(N[C@H](C)[C@H](C)O)n2)cc1OC CHEMBL3648114 IC50 6.0 nM
COC[C@H](Nc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br)[C@H](C)O CHEMBL3648119 IC50 6.0 nM
C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(S(=O)(=O)C3CC3)cc2)ncc1C(F)(F)F CHEMBL3644032 IC50 6.0 nM
Clc1ccccc1-c1cc(NCc2ccncc2)n2ncc(Br)c2n1 CHEMBL3642650 IC50 6.0 nM
CC(C)S(=O)(=O)c1ccc(Nc2ncc(C(F)(F)F)c(O[C@H](C)[C@@H](C)O)n2)cc1 CHEMBL3644024 IC50 6.0 nM
CC(C)c1cnn2c(NCc3ccccc3-n3cccn3)nc(OC3CCCNC3)nc12 CHEMBL4562323 IC50 6.4 nM
NS(=O)(=O)c1cccc(Nc2nccc(-c3ccnc(NCCCO)c3)n2)c1 CHEMBL2158843 IC50 6.7 nM
CC(C)(CO)CNC(=O)c1ccc2c(c1)/C(=N/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL410072 IC50 6.8 nM
NCCCc1cc(-c2ccc[nH]2)c2c3c(ccc(F)c13)NC2=O CHEMBL312726 IC50 7.0 nM
CN(C)S(=O)(=O)c1ccc(Nc2cc(N[C@H]3CC[C@H](N)CC3)nc3c(C#N)cnn23)cc1 CHEMBL360573 IC50 7.0 nM
COc1ccc(F)cc1C(=O)c1cnc(NC2CCN(S(C)(=O)=O)CC2)nc1N CHEMBL268507 Ki 7.0 nM
Cc1ccc(CC(=O)Nc2n[nH]c3ccc(N4CCCS4(=O)=O)cc23)cc1 CHEMBL256558 IC50 7.0 nM
O=C(Cc1ccc(Br)cc1)Nc1n[nH]c2ccc(N3CCCS3(=O)=O)cc12 CHEMBL402370 IC50 7.0 nM
O=C(Cc1cccc(Br)c1)Nc1n[nH]c2ccc(N3CCCS3(=O)=O)cc12 CHEMBL402158 IC50 7.0 nM
CC(C)(C)c1cnc(CSc2cnc(N[C@H]3CC[C@H](O)CC3)s2)o1 CHEMBL495557 IC50 7.0 nM
CCS(=N)(=O)c1ccc(Nc2ncc(Br)c(N[C@H](COC)[C@H](C)O)n2)cc1 CHEMBL3648094 IC50 7.0 nM
CN=S(C)(=O)c1ccc(Nc2ncc(Br)c(N[C@H](C)[C@H](C)O)n2)cc1 CHEMBL3648083 IC50 7.0 nM
Cc1cc(Nc2ncc(Br)c(N[C@@H](C)C(C)(C)O)n2)ccc1S(C)(=N)=O CHEMBL3648125 IC50 7.0 nM
N[C@H]1CC[C@H](Nc2nc(Nc3ccccc3)c3ncn(C4CCCC4)c3n2)CC1 CHEMBL3084839 IC50 7.0 nM
N[C@H]1CC[C@H](Nc2nc(NCc3ccccc3)c3ncn(C4CCCC4)c3n2)CC1 CHEMBL150261 IC50 7.0 nM
NS(=O)(=O)c1ccc(N/N=C2\C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL407709 IC50 7.1 nM
N#Cc1ccc2c(CCNc3ccc(S(F)(F)(F)(F)F)cc3C(=O)O)c[nH]c2c1 CHEMBL5397283 Kd 7.4 nM
NS(=O)(=O)Cc1ccc(N/C=C2\C(=O)Nc3ccc4ncsc4c32)cc1 CHEMBL1964257 IC50 7.5 nM
CN(C)C/C=C/C(=O)Nc1ccc(C(=O)Nc2ncc(SCc3ncc(C(C)(C)C)o3)s2)cc1 CHEMBL4756353 IC50 7.8 nM
CCc1cccc2c1/C(=N/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL411425 IC50 7.9 nM
N#CCOc1ccc(Nc2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2Br)cc1 CHEMBL1987034 pKi 7.943 nM
COc1ccc(CNc2cc(-c3c[nH]c4ncccc34)cc(F)n2)cc1 CHEMBL1986855 pKi 7.943 nM
CN(C)S(=O)(=O)c1ccc(Nc2cc(N[C@H]3CC[C@H](N)CC3)nc3c(Cl)cnn23)cc1 CHEMBL367150 IC50 8.0 nM
Oc1ccc2c(-c3ccnc(Nc4cccc(C(F)(F)F)c4)n3)cnn2n1 CHEMBL187750 Ki 8.0 nM
CN(C)CCNS(=O)(=O)c1ccc(Nc2nccc(-c3cnc4cccnn34)n2)cc1 CHEMBL484571 IC50 8.0 nM
COCCNS(=O)(=O)c1ccc(Nc2nccc(-c3cnc(C)n3C)n2)cc1 CHEMBL520187 IC50 8.0 nM
CCCS(=O)(=O)c1ccc(Nc2nccc(-c3cnc(C)n3C(C)C)n2)cc1 CHEMBL485240 IC50 8.0 nM
COc1ccc(Nc2nccc(-c3cnc(C)n3C(C)C)n2)cc1 CHEMBL478828 IC50 8.0 nM
Cc1ncc(-c2nc(Nc3ccc(N4CCOCC4)cc3)ncc2F)n1C(C)C CHEMBL515001 IC50 8.0 nM
Cc1ncc(-c2ccnc(Nc3ccc(C(=O)N(C)C)cc3)n2)n1C(C)C CHEMBL488085 IC50 8.0 nM
CC(C)(O)CSc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br CHEMBL3648128 IC50 8.0 nM
COc1cc(Nc2ncc(Br)c(O[C@H](C)[C@H](C)O)n2)ccc1S(C)(=N)=O CHEMBL3648082 IC50 8.0 nM
CC(O)C(C)Sc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br CHEMBL3648102 IC50 8.0 nM
C[C@@H](Nc1nc(Nc2ccc(S(=N)(=O)C3CC3)cc2)ncc1Br)C(C)(C)O CHEMBL3648074 IC50 8.0 nM
C[C@@H](Oc1nc(Nc2ccc(S(C)(=O)=O)cc2)ncc1C(F)(F)F)C(C)(C)O CHEMBL3644034 IC50 8.0 nM
O=C(Nc1cccc2c1C(=O)c1c(-c3ccc(C(=O)N4CCNCC4)s3)n[nH]c1-2)NN1CCOCC1 CHEMBL334285 IC50 8.0 nM
CC(C)CC(=O)Nc1n[nH]c2c1CN(C(=O)C1CCN(C)CC1)C2(C)C CHEMBL1230607 IC50 8.0 nM
NS(=O)(=O)c1ccc(N/N=C2\C(=O)Nc3ccc(C(=O)NCc4ccncc4)cc32)cc1 CHEMBL272165 IC50 8.9 nM
CCOC(=O)c1cccc2c1/C(=C/Nc1ccc(S(N)(=O)=O)cc1)C(=O)N2 CHEMBL408210 IC50 8.9 nM
O=C1Nc2ccc(-c3cnco3)cc2/C1=C/Nc1ccc2c(c1)CS(=O)(=O)C2 CHEMBL1234087 IC50 8.9 nM
Clc1cccc(Nc2nccc(-c3ccnc(N4CCOCC4)c3)n2)c1 CHEMBL2158844 IC50 8.9 nM
Cc1cc(CC(=O)Nc2cc(C3CC3)[nH]n2)ccc1-c1ccccc1 CHEMBL490480 pIC50 8.995 nM
CNS(=O)(=O)c1ccc2c(c1)/C(=C/c1[nH]cc3c1CCNC3=O)C(=O)N2 CHEMBL294884 IC50 9.0 nM
O=C1Nc2cccc(C3CCNCC3)c2/C1=C/c1[nH]cc2c1CCOC2=O CHEMBL58224 IC50 9.0 nM
O=C(Cc1ccc2ccccc2c1)Nc1n[nH]c2ccc(N3CCCS3(=O)=O)cc12 CHEMBL254979 IC50 9.0 nM
O=C(Cc1ccc(O)cc1)Nc1n[nH]c2ccc(N3CCCS3(=O)=O)cc12 CHEMBL255718 IC50 9.0 nM
CC(C)(C)c1cnc(CSc2cnc(NC3CCCCC3)s2)o1 CHEMBL496785 IC50 9.0 nM
Cc1ncc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)n1C(C)C CHEMBL514690 IC50 9.0 nM
Cc1cc(Nc2ncc(F)c(-c3cnc(C)n3C(C)C)n2)ccc1C(=O)N(C)C CHEMBL508739 IC50 9.0 nM
Cc1ncc(-c2ccnc(Nc3ccc(C(=O)N4CCN(C)CC4)cc3)n2)n1C(C)C CHEMBL455467 IC50 9.0 nM
Nc1nc(N)c(N=O)c(=O)[nH]1 CHEMBL291324 IC50 9.0 nM
COc1ccc(-c2[nH]nc3c2C(=O)c2c(NC(=O)NNC(=O)c4ccc(O)cc4)cccc2-3)cc1 CHEMBL362560 IC50 9.0 nM
Cc1cc(Nc2ncc3c(n2)CN(C(=O)N[C@H](C)c2ccc(Cl)c(Cl)c2)CC3)ccn1 CHEMBL3298418 IC50 9.0 nM
CCS(=N)(=O)c1ccc(Nc2ncc(Br)c(N[C@@H](COC)[C@H](C)O)n2)cc1 CHEMBL3648121 IC50 9.0 nM
CCS(=N)(=O)c1ccc(Nc2ncc(Br)c(N[C@H](COC)[C@@H](C)O)n2)cc1 CHEMBL3648120 IC50 9.0 nM
CCOC(=O)N=S(C)(=O)c1ccc(Nc2ncc(Br)c(N[C@H](C)C(C)(C)O)n2)cc1 CHEMBL3648084 IC50 9.0 nM
C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc([S@](=N)(=O)C3CC3)cc2)ncc1C(F)(F)F CHEMBL4282338 IC50 9.0 nM
C[C@@H](O)[C@@H](C)Nc1nc(Nc2ccc([S@](=N)(=O)C3CC3)cc2)ncc1C(F)(F)F CHEMBL5287128 IC50 9.0 nM
CC(C)c1n[nH]c2c(NCc3ccc(-c4ccccn4)cc3)nc(NCC(C)(C)O)nc12 CHEMBL3775792 IC50 9.0 nM
NS(=O)(=O)c1ccc(Nc2cc(-c3cccc(O)c3)n[nH]2)cc1 CHEMBL103104 IC50 9.1 nM
CN1CCN(Cc2ccc(NC(=O)c3n[nH]cc3Nc3ncnc4sccc34)cc2)CC1 CHEMBL4075720 IC50 9.1 nM
NS(=O)(=O)c1ccc(N/N=C2\C(=O)Nc3cccc(/C=C/c4ccc(O)cc4)c32)cc1 CHEMBL272380 IC50 9.3 nM
O=C1Nc2ccc3ncsc3c2/C1=C/Nc1ccc(S(=O)(=O)N[n+]2ccc3ccccc3c2)cc1 CHEMBL2112297 IC50 9.5 nM
NS(=O)(=O)c1ccc(N/N=C2\C(=O)Nc3ccc4[nH]nnc4c32)cc1 CHEMBL271952 IC50 9.5 nM
O=C1Nc2ccc3ncsc3c2/C1=C/Nc1ccc(S(=O)(=O)Nc2ccccn2)cc1 CHEMBL1276446 IC50 9.7 nM
C=CC(=O)Nc1ccc(C(=O)N2CC[C@@H](Nc3ncc(SCc4ncc(C(C)(C)C)o4)s3)C2)cc1 CHEMBL4788136 IC50 9.86 nM