CN1CCc2c(nnn2CC(=O)Nc2ccc(Br)c(S(=O)(=O)N3CC[C@H](C4CC4)C3)c2)C1 CHEMBL4465880 pIC50 6.31 nM
CN1CCc2c(nnn2CC(=O)Nc2ccc(Cl)c(S(=O)(=O)N3CC[C@H](C4CC4)C3)c2)C1 CHEMBL4577486 pKd 7.943 nM
CCOC(=O)Nc1cc(-c2ccc(C)c(NS(C)(=O)=O)c2)nn2c(C)nnc12 CHEMBL3133807 Kd 8.0 nM
COc1cc(-c2cn(C)c(=O)c3cnccc23)cc(OC)c1CN(C)C CHEMBL3823478 Kd 8.8 nM
CN(C)CCCOc1ccc(-c2cc(NCCCn3cccn3)nc(S(C)(=O)=O)n2)cc1 CHEMBL4461619 pKd 10.0 nM
Cn1ncc(Nc2ccc(CCN)cc2)c(Cl)c1=O CHEMBL4872300 Kd 11.0 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-c4cccc(OC)c4)ncn3)CC2)c2cc[nH]c2c1=O CHEMBL4073178 IC50 16.0 nM
CCCS(=O)(=O)c1nc(NC2CC2)cc(-c2ccc3c(ccn3C3CC(C)(C)NC(C)(C)C3)c2)n1 CHEMBL3785432 IC50 19.3 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)N[C@@](C)(C4CC4)C3=O)ccc2Br)C1 CHEMBL4449894 pKd 25.12 nM
CC(C)N1CCc2c(nnn2CC(=O)Nc2ccc(Br)c(S(=O)(=O)N3CC[C@H](C)C3)c2)C1 CHEMBL4514362 pIC50 31.62 nM
CN1CCc2c(nnn2CC(=O)Nc2ccc(Br)c(S(=O)(=O)N3CC[C@@H](C4CC4)C3)c2)C1 CHEMBL4557734 pIC50 39.81 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-c4ccccc4F)ncn3)CC2)c2cc[nH]c2c1=O CHEMBL4075584 IC50 44.0 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-c4ccco4)ncn3)CC2)c2cc[nH]c2c1=O CHEMBL4076944 IC50 45.0 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-c4ccccc4OC)ncn3)CC2)c2cc[nH]c2c1=O CHEMBL4077439 IC50 45.0 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-c4ccccc4C)ncn3)CC2)c2cc[nH]c2c1=O CHEMBL4104121 IC50 46.0 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)Cn3nnc4c3CCN(C)C4)ccc2Br)C1 CHEMBL4437578 pIC50 50.12 nM
CCN1CCc2c(nnn2CC(=O)Nc2ccc(Br)c(S(=O)(=O)N3CC[C@H](C)C3)c2)C1 CHEMBL4518862 pIC50 50.12 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C4CC4)nc(C)n3)CC2)c2cc[nH]c2c1=O CHEMBL4088221 IC50 52.0 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C(C)(C)C)ncn3)CC2)c2cc[nH]c2c1=O CHEMBL4062038 IC50 55.0 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-n4cccn4)ncn3)CC2)c2cc[nH]c2c1=O CHEMBL4062597 IC50 59.0 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)Cn3c(=O)oc4ccccc43)ccc2Br)C1 CHEMBL4436652 pIC50 63.1 nM
Cc1c(Nc2ccc(S(=O)(=O)N3CCN(C)CC3)cc2F)nc2ccc(-c3cnn(C4CC4)c3)cn2c1=O CHEMBL4780673 Kd 66.0 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(OC)nc(C)n3)CC2)c2cc[nH]c2c1=O CHEMBL4081975 IC50 71.0 nM
COc1cc(-c2cn(C)c(=O)c3cnccc23)c(OC)cc1CN(C)C CHEMBL3823101 Kd 77.0 nM
CCCc1cnnn1CC(=O)Nc1ccc(Br)c(S(=O)(=O)N2CC[C@H](C)C2)c1 CHEMBL4467940 pIC50 79.43 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)Cn3nncc3CN(C)C)ccc2Br)C1 CHEMBL4553980 pIC50 79.43 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C4CC4)ncn3)CC2)c2cc[nH]c2c1=O CHEMBL4093696 IC50 83.0 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C)nc(C)n3)CC2)c2cc[nH]c2c1=O CHEMBL4076384 IC50 93.0 nM
CC(=O)N1CCc2c(nnn2CC(=O)Nc2ccc(Br)c(S(=O)(=O)N3CC[C@H](C)C3)c2)C1 CHEMBL4461164 pIC50 100.0 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)N[C@](C)(C4CC4)C3=O)ccc2Br)C1 CHEMBL4589592 pIC50 125.89 nM
C[C@@H]1CN(S(=O)(=O)c2cc(NC(=O)CN3C(=O)NC(C)(C4CC4)C3=O)ccc2Br)C[C@H]1C CHEMBL4576280 pIC50 125.89 nM
CN1CCc2c(nnn2CC(=O)Nc2ccc(Cl)c(S(=O)(=O)N3CC[C@@H](C4CC4)C3)c2)C1 CHEMBL4545743 pIC50 125.89 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(OC)ncn3)CC2)c2cc[nH]c2c1=O CHEMBL4076381 IC50 130.0 nM
CCn1cc(-c2cccc(C(F)(F)F)c2)c2sc(C(=N)NC3CCS(=O)(=O)CC3)cc2c1=O CHEMBL3769507 Kd 140.0 nM
Cc1nnc2c3ccccc3c(-c3ccc(N4CCOCC4)c(NS(C)(=O)=O)c3)nn12 CHEMBL3108800 pIC50 158.49 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)Cn3nnc4c3CCN(CC(F)(F)F)C4)ccc2Br)C1 CHEMBL4537897 pIC50 158.49 nM
C=CCn1cc(-c2cccc(C(=O)N(C)C)c2)c2cc[nH]c2c1=O CHEMBL4460783 IC50 170.0 nM
C=CCn1cc(C(=O)N(C)C2CCN([C@@H](C)c3ccccc3)CC2)c2cc(C)[nH]c2c1=O CHEMBL4077529 IC50 190.0 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)Cn3nnc4ccccc43)ccc2Br)C1 CHEMBL4446238 pIC50 199.53 nM
C=CCn1cc(C(=O)N(C)C2CCN([C@H](C)c3ccccc3)CC2)c2cc(C)[nH]c2c1=O CHEMBL4078864 IC50 200.0 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C(F)(F)F)ncn3)CC2)c2cc[nH]c2c1=O CHEMBL4068293 IC50 200.0 nM
C=CCCn1cc(-c2cc(C(=O)N3CCOCC3)c3c(c2)ncn3C)c2cc[nH]c2c1=O CHEMBL4455513 IC50 230.0 nM
C=CCn1cc(C(=O)N(C)C2CCN(c3ccncn3)CC2)c2cc[nH]c2c1=O CHEMBL4077036 IC50 240.0 nM
CN(C)C(=O)c1cccc(-c2cn(C)c(=O)c3[nH]ccc23)c1 CHEMBL4436408 IC50 240.0 nM
Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)N(C)C CHEMBL3108781 pIC50 251.19 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)Cc3noc4ccccc34)ccc2Br)C1 CHEMBL4470476 pIC50 251.19 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)Cn3cc(CN(C)C)nn3)ccc2Br)C1 CHEMBL4542904 pIC50 251.19 nM
COCc1cnnn1CC(=O)Nc1ccc(Br)c(S(=O)(=O)N2CC[C@H](C)C2)c1 CHEMBL4454840 pIC50 251.19 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)Cn3nnc4c3CN(C)CC4)ccc2Br)C1 CHEMBL4463062 pIC50 251.19 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)Cn3nnc4c3CCNC4)ccc2Br)C1 CHEMBL4558839 pIC50 251.19 nM
CC(c1ccccc1)N1CCC(N(C)C(=O)c2cn(C)c(=O)c3[nH]ccc23)CC1 CHEMBL4061800 IC50 330.0 nM
C=CCCn1cc(-c2cc(C#N)cc(C(=O)N3CCOCC3)c2)c2cc[nH]c2c1=O CHEMBL4448723 IC50 350.0 nM
C=CCCn1cc(-c2cc(C(=O)N3CCOCC3)c3ncn(C)c3c2)c2cc[nH]c2c1=O CHEMBL4513694 IC50 360.0 nM
C/C=C/Cn1cc(-c2ccc(C(=O)N3CCOCC3)c(C#N)c2)c2cc(C)[nH]c2c1=O CHEMBL5268936 IC50 370.0 nM
C[C@@]1(C2CC2)NC(=O)N(CC(=O)Nc2ccc(Br)c(S(=O)(=O)N3CCCC3)c2)C1=O CHEMBL4565203 pIC50 398.11 nM
C/C=C/Cn1cc(-c2cccc(C(=O)N(C)C)c2)c2cc[nH]c2c1=O CHEMBL4519632 IC50 410.0 nM
C/C=C/Cn1cc(-c2ccc(C(=O)N3CCOCC3)c(Cl)c2)c2cc(C)[nH]c2c1=O CHEMBL5285110 IC50 460.0 nM
CC(C)N1CCC(N(C)C(=O)c2cn(C)c(=O)c3[nH]ccc23)CC1 CHEMBL4061901 IC50 500.0 nM
C=CCn1cc(C(=O)N(C)C2CCN(C(C)c3ccccc3)CC2)c2cc[nH]c2c1=O CHEMBL4089866 IC50 500.0 nM
Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1NS(C)(=O)=O CHEMBL3110357 pIC50 501.19 nM
O=C(CN1C(=O)CNC1=O)Nc1ccc(Cl)c(S(=O)(=O)N2CCC(C3CC3)C2)c1 CHEMBL4521850 pIC50 501.19 nM
C[C@H]1CCN(S(=O)(=O)c2cc(NC(=O)Cn3c(=O)[nH]c4ccccc43)ccc2Br)C1 CHEMBL4589461 pIC50 501.19 nM
C=CCCn1cc(-c2cccc(C(=O)N3CCN(C)CC3)c2)c2cc[nH]c2c1=O CHEMBL4572531 IC50 550.0 nM
COc1cc2c(cc1-c1c(C)noc1C)[nH]c1nc(C)nc(Nc3cc(C4CC4)nn3C)c12 CHEMBL4173488 Kd 570.0 nM
C=CCCn1cc(-c2cnc(OCC)c(C(=O)N3CCOCC3)c2)c2cc[nH]c2c1=O CHEMBL4440829 IC50 590.0 nM
C=CCCn1cc(-c2cc(C(=O)N3CCOCC3)c3ncn(CC)c3c2)c2cc[nH]c2c1=O CHEMBL4453202 IC50 590.0 nM
C=CCCn1cc(-c2cc(OC(F)F)cc(C(=O)N3CCOCC3)c2)c2cc[nH]c2c1=O CHEMBL4586175 IC50 700.0 nM
CN1CCC(N(C)C(=O)c2cn(C)c(=O)c3[nH]ccc23)CC1 CHEMBL4088418 IC50 780.0 nM
Cc1cncc(-c2cnc(N[C@@H]3CCN(C)C[C@H]3OCC3CCS(=O)(=O)CC3)c3[nH]c(=O)c(C)cc23)c1 CHEMBL3590408 pKi 794.33 nM
C/C=C/Cn1cc(-c2ccc(C(=O)N3CCOCC3)cc2)c2cc(C)[nH]c2c1=O CHEMBL5284261 IC50 810.0 nM
C=CCCn1cc(-c2cc(C(=O)N3CCOCC3)c3nc[nH]c3c2)c2cc[nH]c2c1=O CHEMBL4468549 IC50 820.0 nM
C=CCCn1cc(-c2cncc(C(=O)N3CCOCC3)c2)c2cc[nH]c2c1=O CHEMBL4459431 IC50 830.0 nM
Cc1[nH]c(-c2cc(N)ccc2Cl)c2c1C(=O)CCCC2 CHEMBL5439294 Kd 970.0 nM
COc1ccc(S(=O)(=O)Nc2cc(-c3nn4c(C)nnc4c4ccccc34)ccc2N2CCN(C)CC2)cc1 CHEMBL3110353 pIC50 1000.0 nM
C=CCCn1cc(-c2cnc(OC)c(C(=O)N3CCOCC3)c2)c2cc[nH]c2c1=O CHEMBL4566599 IC50 1000.0 nM
Cc1nnn(CC(=O)Nc2ccc(Br)c(S(=O)(=O)N3CC[C@H](C)C3)c2)c1C CHEMBL4590565 pIC50 1000.0 nM
Cc1cc2c(C3=CCOCC3)cnc(NC3CCN(C(=O)C(F)(F)CN)CC3)c2[nH]c1=O CHEMBL4864027 pKi 1000.0 nM
C/C=C/Cn1cc(-c2ccc(C(=O)N3CCOCC3)c(C)c2)c2cc(C)[nH]c2c1=O CHEMBL5280605 IC50 1000.0 nM
C/C=C/Cn1cc(-c2ccc(C(=O)N3CCOCC3)c(OC)c2)c2cc(C)[nH]c2c1=O CHEMBL5279182 IC50 1000.0 nM