CCCCCC[Se](=O)CC(=O)C(F)(F)F CHEMBL155514 -Log IC50 0.1778 nM
Cc1ccc(C(=O)C(=O)c2ccccc2)cc1C CHEMBL193140 Ki 3.2 nM
CCCCCC[Se](=O)(=O)CC(=O)C(F)(F)F CHEMBL155513 -Log IC50 3.388 nM
CCOC(=O)/C(=N\Nc1ccccc1[N+](=O)[O-])C(=O)C(F)(F)F CHEMBL4854298 IC50 4.04 nM
CCOC(=O)/C(=N\Nc1ccccc1)C(=O)C(F)(F)F CHEMBL4853742 IC50 4.33 nM
Cc1ccc(C(=O)C(=O)c2ccccc2)cc1[N+](=O)[O-] CHEMBL191847 Ki 4.4 nM
O=C(C(=O)c1cccc(F)c1F)c1cccc(F)c1F CHEMBL395018 Ki 4.98 nM
CCCCCCNCC(=O)C(F)(F)F CHEMBL153080 -Log IC50 5.495 nM
O=C(C(=O)c1ccc(C(=O)C(=O)c2ccccc2)cc1)c1ccccc1 CHEMBL362996 Ki 5.6 nM
CCCCCCCCC(=O)C(=O)CCCCCCCC CHEMBL1812859 Ki 5.7 nM
CCCCCCCCSCC(=O)C(F)(F)F CHEMBL89506 IC50 5.8 nM
CCCCCCSCC(=O)C(F)(F)F CHEMBL440542 -Log IC50 6.918 nM
CCCCCCCC[S+]([O-])CC(=O)C(F)(F)F CHEMBL270373 IC50 7.4 nM
COc1ccc(C(=O)C(=O)c2ccccc2Cl)cc1OC CHEMBL191822 Ki 8.9 nM
CCOC(=O)/C(=N\Nc1ccc(F)cc1)C(=O)C(F)(F)F CHEMBL4858186 IC50 9.84 nM
COc1ccc(C(=O)C(=O)c2ccccc2)cc1 CHEMBL192474 Ki 10.3 nM
CCOC(=O)/C(=N\Nc1ccc(Br)cc1)C(=O)C(F)(F)F CHEMBL4868014 IC50 10.81 nM
O=C(C(=O)c1ccc(F)c(F)c1F)c1ccc(F)c(F)c1F CHEMBL242931 Ki 13.6 nM
O=C(C(=O)c1ccccc1)c1ccccc1 CHEMBL189886 Ki 14.7 nM
COC(=O)/C(=N\Nc1ccccc1[N+](=O)[O-])C(=O)C(F)(F)F CHEMBL4855838 IC50 16.92 nM
O=C(C(=O)c1ccc(Cl)cc1)c1ccccc1 CHEMBL192180 Ki 18.2 nM
O=C(C(=O)c1ccc(Br)cc1)c1ccc(Br)cc1 CHEMBL193228 Ki 18.6 nM
CCCCCCCCCCC(=O)C(F)(F)F CHEMBL86668 IC50 20.0 nM
CCOC(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)CCC(=O)O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2C1 CHEMBL3774603 IC50 20.0 nM
CCCCCCCCS(=O)(=O)CC(=O)C(F)(F)F CHEMBL273139 IC50 21.0 nM
O=C(C(=O)c1ccc(CBr)cc1)c1ccccc1 CHEMBL192241 Ki 21.3 nM
Cc1ccc(C(=O)C(=O)c2ccc(Cl)cc2)cc1 CHEMBL192252 Ki 22.8 nM
O=C(C(=O)c1cc(F)cc(F)c1)c1cc(F)cc(F)c1 CHEMBL193229 Ki 23.0 nM
CCOC(=O)/C(=N\Nc1cccc(C)c1)C(=O)C(F)(F)F CHEMBL4853637 IC50 23.44 nM
CCCCCCCC(=O)C(=O)CCCCCCC CHEMBL1812858 Ki 25.6 nM
O=C(c1ccc(F)c(F)c1F)C(O)c1ccc(F)c(F)c1F CHEMBL244631 Ki 25.7 nM
O=C(C(=O)c1cccc(F)c1)c1cccc(F)c1 CHEMBL242067 Ki 25.9 nM
O=C(C(=O)c1ccc(Cl)cc1)c1ccc(Cl)cc1 CHEMBL192139 Ki 27.5 nM
CCCCCCC(=O)C(=O)c1ccccc1 CHEMBL1812864 Ki 28.7 nM
O=C(C(=O)c1ccc([N+](=O)[O-])cc1)c1ccccc1 CHEMBL192589 Ki 30.6 nM
O=C(C(=O)c1cc(F)cc(F)c1F)c1cc(F)cc(F)c1F CHEMBL242930 Ki 31.9 nM
O=C1C(=O)N(Cc2ccc(Cl)cc2)c2ccccc21 CHEMBL376291 Ki 32.0 nM
CCCCCCCC(F)(F)C(=O)C(F)(F)F CHEMBL153015 -Log IC50 32.36 nM
Cc1ccc(C(=O)C(=O)c2ccccc2)cc1 CHEMBL371858 Ki 33.3 nM
O=C1C=C(Oc2ccc(I)cc2)c2ccccc2C1=O CHEMBL4071772 Ki 33.9 nM
CC(C)C1=Cc2ccc3c(c2C(=O)C1=O)CCCC3(C)C CHEMBL45830 Ki 40.0 nM
O=C(C(=O)c1c(F)ccc(F)c1F)c1cc(F)cc(F)c1F CHEMBL242722 Ki 40.7 nM
CCCCCC(=O)C(=O)c1ccccc1 CHEMBL1812863 Ki 45.5 nM
CCCCCCS(=O)(=O)CC(=O)C(F)(F)F CHEMBL155621 -Log IC50 46.77 nM
COC(=O)/C(=N\Nc1ccccc1)C(=O)C(F)(F)F CHEMBL4849436 IC50 47.74 nM
CCCCCCOCC(=O)C(F)(F)F CHEMBL421992 -Log IC50 47.86 nM
O=C1C(=O)c2ccccc2-c2ccccc21 CHEMBL51931 Ki 52.0 nM
COc1cc(/C=C2\Cc3ccc(N4CCCC4)cc3C2=O)ccc1O CHEMBL4776624 IC50 52.0 nM
O=C(c1cc(F)ccc1F)C(O)c1cc(F)ccc1F CHEMBL244428 Ki 55.2 nM
O=C(C(=O)c1ccccc1F)c1ccccc1F CHEMBL244633 Ki 55.9 nM
O=C1C(Cl)=C(Cl)C(=O)C(Cl)=C1Cl CHEMBL192627 Ki 57.4 nM
CCCCCC(=O)C(=O)CCCCC CHEMBL1812856 Ki 57.7 nM
Cc1ccc(C(=O)C(=O)c2ccc(C)cc2)cc1 CHEMBL192625 Ki 60.4 nM
O=C(C(=O)c1cc(F)ccc1F)c1cc(F)ccc1F CHEMBL242721 Ki 61.4 nM
Cc1ccc(OC2=CC(=O)C(=O)c3ccccc32)cc1 CHEMBL4101254 Ki 61.5 nM
Cc1coc2c1C(=O)C(=O)c1c-2ccc2c1CCCC2(C)C CHEMBL187266 Ki 69.4 nM
COc1ccc(C(=O)C(=O)c2ccc(OC)cc2)cc1 CHEMBL191513 Ki 70.2 nM
CCOC(=O)/C(=N\Nc1ccc(OC)cc1)C(=O)C(F)(F)F CHEMBL4855755 IC50 70.51 nM
O=C(c1cc(F)cc(F)c1)C(O)c1cc(F)cc(F)c1 CHEMBL437373 Ki 71.0 nM
O=C(O)c1ccc(C(=O)C(=O)c2ccccc2)cc1 CHEMBL370059 Ki 71.5 nM
O=C(C(=O)C1CCCCC1)C1CCCCC1 CHEMBL235287 Ki 72.0 nM
CCOC(=O)/C(=N\Nc1ccc(C)cc1)C(=O)C(F)(F)F CHEMBL4849361 IC50 72.31 nM
O=C(C(=O)c1cc(Br)ccc1O)c1cc(Br)ccc1O CHEMBL366205 Ki 72.7 nM
CCCCC(=O)C(=O)c1ccccc1 CHEMBL1812862 Ki 72.7 nM
CCCCCCC(=O)C(=O)CCCCCC CHEMBL1812857 Ki 76.4 nM
O=C(C(=O)c1ccc2ccccc2c1)c1ccc2ccccc2c1 CHEMBL189162 Ki 85.0 nM
Cc1ccc(CC2C(=O)N(C3CCCCC3)N=C2c2ccc(C)cc2)cc1 CHEMBL4851375 Ki 90.0 nM
O=C(c1cc(F)cc(F)c1F)C(O)c1cc(F)cc(F)c1F CHEMBL244630 Ki 99.5 nM
CCCCCC[Se]CC(=O)C(F)(F)F CHEMBL153177 -Log IC50 100.0 nM
CC1(C)CCC2=C(O1)c1ccccc1C(=O)C2=O CHEMBL15192 Ki 109.0 nM
O=C1C=C(Oc2ccc(Br)cc2)c2ccccc2C1=O CHEMBL4098780 Ki 110.0 nM
Cc1cccc2c3c(ccc12)C1=C(C(=O)C3=O)[C@@H](C)CO1 CHEMBL227075 Ki 118.0 nM
O=C(c1c(F)cccc1F)C(O)c1c(F)cccc1F CHEMBL244426 Ki 120.0 nM
O=C1C=C(Oc2ccc(Cl)cc2)c2ccccc2C1=O CHEMBL4082280 Ki 127.4 nM
COc1cccc(C(=O)C(=O)c2cccc(OC)c2)c1 CHEMBL435109 Ki 139.0 nM
CCCCC(=O)C(=O)CCCC CHEMBL1812855 Ki 140.0 nM
C[C@H]1COC2=C1C(=O)C(=O)c1c2ccc2c1CCCC2(C)C CHEMBL187460 Ki 141.0 nM
O=C(C(=O)c1ccc(F)c(F)c1)c1ccc(F)c(F)c1 CHEMBL397739 Ki 150.0 nM
O=C(c1ccc(F)c(F)c1)C(O)c1ccc(F)c(F)c1 CHEMBL394557 Ki 150.0 nM
O=C(C(=O)c1ccccn1)c1ccccn1 CHEMBL373345 Ki 152.0 nM
O=C(C(=O)c1ccc(F)cc1)c1ccc(F)cc1 CHEMBL192410 Ki 167.0 nM
O=C1C(=O)c2cccc3cccc1c23 CHEMBL395653 Ki 170.0 nM
O=C(C(=O)c1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)cc1 CHEMBL242932 Ki 180.0 nM
O=C1C=C(Oc2ccc(F)cc2)c2ccccc2C1=O CHEMBL4060374 Ki 182.2 nM
COC(=O)/C(=N\Nc1ccc(C)cc1)C(=O)C(F)(F)F CHEMBL4868687 IC50 193.34 nM
COc1ccc(OC2=CC(=O)C(=O)c3ccccc32)cc1 CHEMBL2391135 Ki 195.5 nM
O=C1C=C(Oc2ccccc2)c2ccccc2C1=O CHEMBL2391134 Ki 199.8 nM
O=C(C(=O)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])c1ccccc1 CHEMBL365517 Ki 209.0 nM
O=C(c1cccc(C(F)(F)F)c1)C(O)c1cccc(C(F)(F)F)c1 CHEMBL244632 Ki 220.0 nM
COC(=O)/C(=N\Nc1ccc(OC)cc1)C(=O)C(F)(F)C(F)(F)C(F)(F)F CHEMBL4849604 IC50 230.09 nM
O=C(C(=O)c1ccc(Br)s1)c1ccc(Br)s1 CHEMBL192592 Ki 237.0 nM
O=C(C(=O)c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1 CHEMBL395019 Ki 250.0 nM
O=C(c1ccccc1F)C(O)c1ccccc1F CHEMBL242768 Ki 250.0 nM
O=C(C(=O)c1cc(F)c(F)c(F)c1)c1cc(F)c(F)c(F)c1 CHEMBL193180 Ki 259.0 nM
O=C(c1cccc(F)c1F)C(O)c1cccc(F)c1F CHEMBL244427 Ki 260.0 nM
CN(C(=O)n1cnc(-c2ccc[n+]([O-])c2)c1)C1CCCCC1 CHEMBL4460898 IC50 260.0 nM
O=C(Cc1ccccc1)C(=O)C(Br)c1ccccc1 CHEMBL1812852 Ki 267.0 nM
O=C(C(=O)c1ccc(F)cc1F)c1ccc(F)cc1F CHEMBL242287 Ki 270.0 nM
CN(C1=CC(=O)C(=O)c2ccccc21)c1ccc(I)cc1 CHEMBL4068175 Ki 284.0 nM
CCCCCC[S+]([O-])CC(=O)C(F)(F)F CHEMBL155396 -Log IC50 309.03 nM
O=C(C(=O)C(Br)c1ccccc1)C(Br)c1ccccc1 CHEMBL1812851 Ki 334.0 nM
COC(=O)/C(=N\Nc1ccc(OC)cc1)C(=O)C(F)(F)F CHEMBL4872772 IC50 339.25 nM
O=C(C(=O)c1ccccc1Cl)c1ccccc1Cl CHEMBL365392 Ki 353.0 nM
O=C(C(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl)c1c(F)c(F)c(F)c(F)c1F CHEMBL195713 Ki 380.0 nM
CCN(CC)c1ccc2c(c1)C(=O)/C(=C/c1ccc(O)c(OC)c1)C2 CHEMBL4748399 IC50 380.0 nM
O=C(c1ccc(F)cc1F)C(O)c1ccc(F)cc1F CHEMBL244425 Ki 390.0 nM
O=C(C(=O)c1cccc([N+](=O)[O-])c1)c1cccc([N+](=O)[O-])c1 CHEMBL191796 Ki 397.0 nM
O=C(c1ccc(C(F)(F)F)cc1)C(O)c1ccc(C(F)(F)F)cc1 CHEMBL394807 Ki 400.0 nM
CCCC(=O)C(=O)c1ccccc1 CHEMBL1812861 Ki 401.0 nM
O=C(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 CHEMBL242506 Ki 550.0 nM
O=C(C(=O)c1cc(Br)cs1)c1cc(Br)cs1 CHEMBL190672 Ki 573.0 nM
COc1cc(/C=C2\Cc3ccc(N4CCCCC4)cc3C2=O)ccc1O CHEMBL4740149 IC50 610.0 nM
CCOC(=O)/C(=N\Nc1ccc(C)cc1)C(=O)C(F)(F)C(F)(F)F CHEMBL4853013 IC50 610.24 nM
COc1cc(/C=C2\Cc3ccc(NC(C)=O)cc3C2=O)ccc1O CHEMBL4780848 IC50 630.0 nM
O=C(c1cccc(F)c1)C(O)c1cccc(F)c1 CHEMBL396977 Ki 640.0 nM
CCOC(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)C(=CC(=O)[C@@H]4[C@@]5(C)CC[C@H](OC(=O)CCC(=O)O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2C1 CHEMBL2151605 IC50 660.0 nM
COc1cc(/C=C2\Cc3ccc(N4CCCCCC4)cc3C2=O)ccc1O CHEMBL4748929 IC50 810.0 nM
O=C(C(=O)c1c(F)cccc1F)c1c(F)cccc1F CHEMBL242288 Ki 830.0 nM
O=C1C(=O)C(Cl)=C(Cl)C(Cl)=C1Cl CHEMBL364729 Ki 875.0 nM
O=C1C(=O)N(c2ccccc2)c2ccccc21 CHEMBL117447 Ki 950.0 nM