N#CCOc1ccc2c(c1)c(NC(=O)N1[C@@H]3C[C@@H]3C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL2180765 IC50 1.0 nM
CCN[C@H](CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)c(F)c3n2)CC1)c1ccc(C#N)cc1 CHEMBL4114217 IC50 1.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](NCC4(C)COC4)c4ccc(C#N)cc4)CC3)nc2c(F)c1OC CHEMBL4106993 IC50 1.0 nM
C[C@@]1(F)C[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccc(OCC(=O)O)cc23)C1 CHEMBL2180764 IC50 2.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2cnc(CF)cc12 CHEMBL3109655 IC50 2.0 nM
CC(C)(C)OC(=O)Cc1ccc2c(NC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NCc3cccc(Cl)c3F)cn(C(N)=O)c2c1 CHEMBL2180766 IC50 3.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(I)n2)c2ccccc12 CHEMBL3109654 IC50 3.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668673 IC50 3.0 nM
COc1ccc2c(c1)c(NC(=O)N1C[C@H](F)C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3673724 IC50 3.0 nM
COC(=O)COc1ccc2c(c1)c(NC(=O)N1C[C@](C)(F)C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3673750 IC50 3.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(O)ccc21 CHEMBL3673802 IC50 3.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCC(=O)O)ccc21 CHEMBL3673804 IC50 3.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3678905 IC50 3.0 nM
CCc1cc2c(C(N)=O)nn(CC(=O)N3C[C@H](F)[C@@H](OC)[C@H]3C(=O)NCc3cccc(Cl)c3F)c2cn1 CHEMBL3678910 IC50 3.0 nM
CCc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(Br)n3)c2cn1 CHEMBL3678945 IC50 3.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cncc(Br)n2)c2ccccc12 CHEMBL3683717 IC50 3.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](NC(C)C)c4ccc(C#N)cc4)CC3)nc2c(F)c1OC CHEMBL4107243 IC50 3.0 nM
CCNC(=O)[C@H](CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)c(F)c3n2)CC1)c1ccc(F)cc1 CHEMBL4113469 IC50 3.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](C)[C@H]2CC2(Cl)Cl)c2ccc(OCc3ncn(C)n3)cc12 CHEMBL4115620 IC50 3.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](C)[C@H]2CC2(Cl)Cl)c2ccc(OCc3cc(C)[nH]n3)cc12 CHEMBL4106731 IC50 3.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@@H]2C(C)C2(Cl)Cl)c2ccc(OCc3ncccn3)cc12 CHEMBL4111856 IC50 3.0 nM
N[C@H](CO)c1cccc(-c2cc(Br)cc(COc3ccccc3CC(=O)O)c2)c1 CHEMBL4535197 IC50 3.0 nM
CC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](CO)c2cccc(Cl)c2F)c2ccccc21 CHEMBL3668636 IC50 4.0 nM
COc1ccc2c(c1)c(NC(=O)N1C3CC3C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3673732 IC50 4.0 nM
CCOC(=O)Cc1ccc2c(c1)c(NC(=O)N1[C@@H]3C[C@@H]3C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3673738 IC50 4.0 nM
C[C@@]1(F)C[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccc(OCCO)cc23)C1 CHEMBL3673812 IC50 4.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(Br)n3)c2cn1 CHEMBL3678944 IC50 4.0 nM
C[C@@]12C[C@@H](C(=O)Nc3cccc(Br)n3)N(C(=O)Cn3nc(C(N)=O)c4ccccc43)[C@@H]1C2 CHEMBL3683720 IC50 4.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccc(OCc3ncccn3)cc12 CHEMBL3683724 IC50 4.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2cc(Cl)ccc12 CHEMBL3683725 IC50 4.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccccc21 CHEMBL3683739 IC50 4.0 nM
CN[C@H](CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)c(F)c3n2)CC1)c1ccc(C#N)cc1 CHEMBL4108959 IC50 4.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](NCC4CC4)c4ccsc4)CC3)nc2c(F)c1OC CHEMBL4111681 IC50 4.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccc(Cl)cc21)[C@H]1CC1(Cl)Cl CHEMBL4112203 IC50 4.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](C)[C@H]2CC2(Cl)Cl)c2cc(C)c(OCc3ncccn3)cc12 CHEMBL4114056 IC50 4.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](C)[C@H]2CC2(Cl)Cl)c2ccc(OCc3ccn(C)n3)cc12 CHEMBL4111206 IC50 4.0 nM
CC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccc(-c3cnc(C)nc3)cc12 CHEMBL4250860 IC50 4.0 nM
N[C@H](CO)c1cccc(-c2cc(CO)cc(COc3ccccc3CC(=O)O)c2)c1 CHEMBL4246585 IC50 4.0 nM
COCCOc1ccc2c(c1)c(NC(=O)N1C3CC3C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3668669 IC50 5.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(F)ccc21 CHEMBL3673726 IC50 5.0 nM
NC(=O)n1cc(NC(=O)N2N=CC[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673793 IC50 5.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCCO)ccc21 CHEMBL3673808 IC50 5.0 nM
CO[C@H]1[C@@H](C(=O)Nc2cccc(OC(F)(F)F)c2F)N(C(=O)Cn2nc(C(C)=O)c3cc(OCc4ncccn4)ccc32)C[C@@H]1F CHEMBL3678852 IC50 5.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(-c3ccccc3Cl)c2F)c2cnccc12 CHEMBL3678898 IC50 5.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(Br)n3)c2c(C)n1 CHEMBL3683719 IC50 5.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3[C@H](C(=O)Nc4cccc(Br)n4)C[C@@]4(C)C[C@@H]34)c2cn1 CHEMBL3965664 IC50 5.0 nM
CO[C@H]1[C@@H](C(=O)Nc2cccc(Br)n2)N(C(=O)Cn2nc(C(N)=O)c3ccccc32)C[C@@H]1F CHEMBL3683730 IC50 5.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccccc21 CHEMBL3683737 IC50 5.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)c4cc5cc(C#N)ccc5[nH]4)C[C@@H]3c3ccccc3)nc2c(F)c1OC CHEMBL4114574 IC50 5.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2ccc(OCc3nccs3)cc12 CHEMBL4108241 IC50 5.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccccc12 CHEMBL3683753 IC50 5.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(C(F)(F)F)n3)c2c(C)n1 CHEMBL3109653 IC50 6.0 nM
COC(=O)COc1ccc2c(c1)c(NC(=O)N1C3CC3C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3668640 IC50 6.0 nM
NC(=O)n1cc(NC(=O)N2CCS[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668685 IC50 6.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](CO)c2cccc(Cl)c2F)c2ccccc21 CHEMBL3668710 IC50 6.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(OCc3ncccn3)cc12 CHEMBL3678879 IC50 6.0 nM
Cc1nccc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)N[C@H](C)c3cccc(Cl)c3F)c12 CHEMBL3678906 IC50 6.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnc(C3CC3)cc12 CHEMBL3678913 IC50 6.0 nM
CC(C)=C(F)[C@@H](C)NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccccc21 CHEMBL4114680 IC50 6.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)/C=C/c4ccc(C#N)cc4)C[C@@H]3c3ccccc3)nc2c(F)c1OC CHEMBL4107774 IC50 6.0 nM
CC[C@H]1CN(C(=O)c2cc3cc(C#N)ccc3[nH]2)CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1 CHEMBL3928150 IC50 6.0 nM
CN[C@H](CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)c(F)c3n2)CC1)c1ccc(F)cc1 CHEMBL4114991 IC50 6.0 nM
CCN[C@H](CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)c(F)c3n2)CC1)c1ccc(F)cc1 CHEMBL4114221 IC50 6.0 nM
COCCCN[C@H](CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)c(F)c3n2)CC1)c1ccc(F)cc1 CHEMBL4107659 IC50 6.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](NCCF)c4ccc(F)cc4)CC3)nc2c(F)c1OC CHEMBL4109971 IC50 6.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@H](c4ccc(F)cc4)N4CCCCC4)CC3)nc2c(F)c1OC CHEMBL4115570 IC50 6.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](C)C2CC2(Cl)Cl)c2ccc(OCc3ncccn3)cc12 CHEMBL4113964 IC50 6.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](C)[C@H]2CC2(Cl)Cl)c2ccc(OCc3cc(C)n(C)n3)cc12 CHEMBL4113412 IC50 6.0 nM
C[C@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2cccnc21)c1cccc(Cl)c1F CHEMBL4753864 IC50 6.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3663968 IC50 7.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2ccc(Cl)s2)c2ccccc21 CHEMBL3663978 IC50 7.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C[C@@H]1F CHEMBL3668711 IC50 7.0 nM
COc1ccc2c(c1)c(NC(=O)N1C[C@H](F)C[C@H]1C(=O)Nc1cccc(OC(F)(F)F)c1F)cn2C(N)=O CHEMBL3673730 IC50 7.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](CO)c2cccc(Cl)c2)c2ccccc21 CHEMBL3673752 IC50 7.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(CCO)ccc21 CHEMBL3673814 IC50 7.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(O)cc21 CHEMBL3673821 IC50 7.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(O)cc21 CHEMBL3673822 IC50 7.0 nM
NC(=O)n1cc(NC(=O)N2NCC[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673860 IC50 7.0 nM
NC(=O)c1nn(CC(=O)N2C[C@H]3C[C@H]3[C@H]2C(=O)Nc2cccc(Br)n2)c2ccccc12 CHEMBL3683722 IC50 7.0 nM
CO[C@H]1[C@@H](C(=O)Nc2cccc(Br)n2)N(C(=O)Cn2nc(C(C)=O)c3ccccc32)C[C@@H]1F CHEMBL3683732 IC50 7.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ccc(OCC3CCCO3)cc12 CHEMBL3683746 IC50 7.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCC(F)=C(C)C)c2ccc(OCc3ncccn3)cc12 CHEMBL4115683 IC50 7.0 nM
CC(C)=C(F)C(C)NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccccc21 CHEMBL4115682 IC50 7.0 nM
CC[C@H]1CN(C(=O)C[C@@H](N)c2ccc(C#N)cc2)CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1 CHEMBL3943926 IC50 7.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccc(F)cc4)C[C@@H]3c3ccccc3)nc2c(F)c1OC CHEMBL4110511 IC50 7.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2ccc(OCc3nccs3)cc12 CHEMBL4111845 IC50 7.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2C(C)C2(Cl)Cl)c2ccc(OCc3ncccn3)cc12 CHEMBL4108542 IC50 7.0 nM
COC[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Nc1cn(C(N)=O)c2ccccc12)c1cccc(Cl)c1F CHEMBL3668742 IC50 8.0 nM
C=CCOc1ccc2c(c1)c(NC(=O)N1[C@@H]3C[C@@H]3C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3668774 IC50 8.0 nM
COCCOc1ccc2c(c1)c(NC(=O)N1C[C@H](F)C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3673735 IC50 8.0 nM
NC(=O)n1cc(NC(=O)N2[C@H](C(=O)NCc3cccc(Cl)c3F)C[C@@]3(CO)C[C@@H]23)c2ccccc21 CHEMBL3919985 IC50 8.0 nM
CC(C)(O)COc1ccc2c(c1)c(NC(=O)N1C3CC3C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3673815 IC50 8.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Br)c2F)c2ccccc12 CHEMBL3678734 IC50 8.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2nc(C(C)=O)c3ccc(C(=O)O)cc32)C[C@@H]1F CHEMBL3678854 IC50 8.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2cnccc12 CHEMBL3678938 IC50 8.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ccc(OC(C)C#N)cc12 CHEMBL3683745 IC50 8.0 nM
CCCN[C@H](CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)c(F)c3n2)CC1)c1ccc(Cl)s1 CHEMBL4111301 IC50 8.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2ccc(OCc3nccc(C)n3)cc12 CHEMBL4115177 IC50 8.0 nM
NCc1cccc(-c2cccc(COc3ccccc3CC(=O)O)c2)c1 CHEMBL4468000 IC50 8.0 nM
CC(C)(O)c1cc(COc2ccccc2CC(=O)O)cc(-c2cccc([C@H](N)CO)c2)c1 CHEMBL4584532 IC50 8.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2)c2ccccc21 CHEMBL3663975 IC50 9.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Br)c2F)c2ccccc21 CHEMBL3668645 IC50 9.0 nM
NC(=O)n1cc(NC(=O)N2CC3O[C@@H]3[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668653 IC50 9.0 nM
COC[C@@]12C[C@@H](C(=O)NCc3cccc(Cl)c3F)N(C(=O)Nc3cn(C(N)=O)c4ccccc34)[C@@H]1C2 CHEMBL3668691 IC50 9.0 nM
CCc1cc2c(C(N)=O)nn(CC(=O)N3C[C@H](F)[C@@H](OC)[C@H]3C(=O)Nc3cccc(OC(F)(F)F)c3F)c2cn1 CHEMBL3678851 IC50 9.0 nM
NC(=O)c1nn(CC(=O)N2[C@H](C(=O)Nc3cccc(Br)c3F)C[C@@]3(CO)C[C@@H]23)c2ccccc12 CHEMBL3950448 IC50 9.0 nM
COCCOc1ccc2c(c1)c(C(C)=O)nn2CC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)Nc1cccc(OC(F)(F)F)c1F CHEMBL3683754 IC50 9.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCCC(C)(C)C)c2ccc(OCc3ncccn3)cc12 CHEMBL4109667 IC50 9.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccc(C#N)cc4)C[C@@H]3C)nc2c(F)c1OC CHEMBL3957678 IC50 9.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cc(N3CCOCC3)cc(Cl)c2F)c2ccccc21 CHEMBL3663986 IC50 10.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ccccc21 CHEMBL3668682 IC50 10.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H]3C[C@H]3[C@H]2C(=O)N[C@H](CO)c2cccc(Cl)c2F)c2ccccc21 CHEMBL3668718 IC50 10.0 nM
NC(=O)n1cc(NC(=O)N2CCS[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(F)ccc21 CHEMBL3668770 IC50 10.0 nM
O=C(NCc1cccc(Br)c1F)[C@@H]1C[C@@H](F)CN1C(=O)Cn1cc(C(=O)C(F)(F)F)c2ccccc21 CHEMBL3678764 IC50 10.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(OCc3ncccn3)cc12 CHEMBL3678807 IC50 10.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2nc(C(N)=O)c3cc(C)ncc32)C[C@@H]1F CHEMBL3678874 IC50 10.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)c2F)c2ccccc12 CHEMBL3678882 IC50 10.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](CO)c2cccc(Cl)c2F)c2ncccc12 CHEMBL3678890 IC50 10.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(-c3ncccc3Cl)c2F)c2cnccc12 CHEMBL3678901 IC50 10.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccncc21)c1cccc(Cl)c1F CHEMBL3678914 IC50 10.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnccc12 CHEMBL3678915 IC50 10.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccc(C#N)cc4)CC3)nc2c(F)c1OC CHEMBL4112178 IC50 10.0 nM
CCC[C@H]1CN(C(=O)C[C@@H](N)c2ccc(C#N)cc2)CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1 CHEMBL3981421 IC50 10.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@H](c4ccc(F)cc4)N4CCC4)CC3)nc2c(F)c1OC CHEMBL4114531 IC50 10.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](C(N)=O)c4ccc(F)cc4)CC3)nc2c(F)c1OC CHEMBL4113781 IC50 10.0 nM
COCc1cc(COc2ccccc2CC(=O)O)cc(-c2cccc([C@H](N)CO)c2)c1 CHEMBL4483713 IC50 10.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(Cl)ccc12 CHEMBL3678749 IC50 11.0 nM
CO[C@H]1[C@@H](C(=O)NC2(c3cccc(Cl)c3F)CC2)N(C(=O)Cn2nc(C(C)=O)c3ccncc32)C[C@@H]1F CHEMBL3678845 IC50 11.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2nc(N)ccc12 CHEMBL3678889 IC50 11.0 nM
CC[C@H]1CN(C(=O)/C=C/c2ccc(C#N)cc2)CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1 CHEMBL3952833 IC50 11.0 nM
CCC[C@H]1CN(C(=O)c2cc3cc(C#N)ccc3[nH]2)CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1 CHEMBL3905588 IC50 11.0 nM
COc1cc2c(N)nc(N3[C@H](C)CN(C(=O)C[C@@H](NC(C)C)c4ccc(C#N)cc4)C[C@@H]3C)nc2c(F)c1OC CHEMBL4113062 IC50 11.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccncc21)[C@H]1CC1(Cl)Cl CHEMBL4109148 IC50 11.0 nM
NC(=O)n1cc(NC(=O)N2CC[C@@H](O)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668719 IC50 12.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](CCO)c2cccc(Cl)c2F)c2ccccc21 CHEMBL3668729 IC50 12.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(OCc3ccccc3)cc12 CHEMBL3678726 IC50 12.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnc(C)cc12 CHEMBL3678859 IC50 12.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2nc(C(C)=O)c3ccncc32)C[C@@H]1F CHEMBL3678895 IC50 12.0 nM
NC(=O)c1nn(CC(=O)N2[C@H](C(=O)Nc3cccc(Br)n3)C[C@@]3(CO)C[C@@H]23)c2ccccc12 CHEMBL3895672 IC50 12.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](NC(C)C)c4ccc(F)c(C#N)c4)CC3)nc2c(F)c1OC CHEMBL4112415 IC50 12.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](C)[C@H]2CC2(Cl)Cl)c2ccccc12 CHEMBL4106911 IC50 12.0 nM
CC1[C@@H](CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(N)=O)c3ccccc32)C1(Cl)Cl CHEMBL4113915 IC50 12.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ccccc21 CHEMBL4094108 IC50 12.0 nM
N[C@H](CO)c1cccc(-c2cccc(COc3ccccc3CC(=O)O)c2)c1 CHEMBL4548070 IC50 12.0 nM
CCOC(=O)Cc1ccc2c(NC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NCc3cccc(Cl)c3F)cn(C(N)=O)c2c1 CHEMBL3673747 IC50 13.0 nM
NC(=O)n1cc(CC(=O)N2C3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCCO)ccc21 CHEMBL3673879 IC50 13.0 nM
COc1ccc2c(C(C)=O)cn(CC(=O)N3C[C@H](F)[C@@H](OC)[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1 CHEMBL3673912 IC50 13.0 nM
O=C(CO)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Br)c2F)c2ccccc12 CHEMBL3678782 IC50 13.0 nM
CCO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2cc(C(C)=O)c3ccccc32)C[C@@H]1F CHEMBL3678787 IC50 13.0 nM
CO[C@H]1[C@@H](C(=O)Nc2cccc(OC(F)(F)F)c2F)N(C(=O)Cn2nc(C(N)=O)c3cc(C)ncc32)C[C@@H]1F CHEMBL3678850 IC50 13.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2nc(C(N)=O)c3ccncc32)C[C@@H]1F CHEMBL3678875 IC50 13.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2cnc(C3CC3)cc12 CHEMBL3678930 IC50 13.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccncc12 CHEMBL3683716 IC50 13.0 nM
Cc1nccc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(Br)n3)c12 CHEMBL3683723 IC50 13.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](NC(C)C)c4ccc(F)cn4)CC3)nc2c(F)c1OC CHEMBL4113623 IC50 13.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(F)c2F)c2ccccc21 CHEMBL3668702 IC50 14.0 nM
C[C@@]1(F)C[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 CHEMBL3668712 IC50 14.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ccccc21 CHEMBL3668780 IC50 14.0 nM
CC(=O)n1cc(NC(=O)N2C[C@@](F)(CN)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673841 IC50 14.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2cc(C(C)=O)c3ccccc32)C[C@@H]1F CHEMBL3673930 IC50 14.0 nM
O=C(NCc1cccc(Cl)c1F)[C@@H]1C[C@@H](F)CN1C(=O)Cn1cc(C(=O)C(F)(F)F)c2ccccc21 CHEMBL3678779 IC50 14.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(C(=O)O)ccc12 CHEMBL3678814 IC50 14.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(C(=O)O)ccc12 CHEMBL3639776 IC50 14.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2cc(C(C)=O)c3ccc(C(=O)O)cc32)C[C@@H]1F CHEMBL3678816 IC50 14.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3CC3C[C@H]2C(=O)NCc2cc(C(=O)O)cc(Cl)c2F)c2ccccc12 CHEMBL3678822 IC50 14.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H]3C[C@H]3[C@H]2C(=O)Nc2cccc(Br)n2)c2ccccc21 CHEMBL3683738 IC50 14.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)c4cc5cc(F)ccc5[nH]4)C[C@@H]3c3ccccc3)nc2c(F)c1OC CHEMBL4113997 IC50 14.0 nM
CO[C@H]1[C@@H](C(=O)N[C@H](C)[C@H]2CC2(Cl)Cl)N(C(=O)Cn2nc(C(N)=O)c3ccccc32)C[C@@H]1F CHEMBL4110563 IC50 14.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2ccc(OCc3cscn3)cc12 CHEMBL4108451 IC50 14.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccccc21)[C@H]1CC1(Cl)Cl CHEMBL4112599 IC50 14.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(C(F)(F)F)n2)c2ccccc21 CHEMBL4098439 IC50 14.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cc(C(=O)O)cc(Cl)c2F)c2ccccc21 CHEMBL3668651 IC50 15.0 nM
NC(=O)n1cc(NC(=O)N2C[C@@](F)(CNC=O)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673839 IC50 15.0 nM
COc1ccc2c(c1)c(CC(=O)N1C3CC3C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3673878 IC50 15.0 nM
COc1ccc2c(c1)c(C(C)=O)cn2CC(=O)N1C[C@H](F)[C@@H](OC)[C@H]1C(=O)NCc1cccc(Cl)c1F CHEMBL3673910 IC50 15.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](CCN(C)C)c2cccc(Cl)c2F)c2ccccc12 CHEMBL3678855 IC50 15.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c(C)n1 CHEMBL3678908 IC50 15.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2cc(C3CC3)ncc21)c1cccc(Cl)c1F CHEMBL3639777 IC50 15.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)c4cc5cc(C#N)ccc5[nH]4)C[C@@H]3C)nc2c(F)c1OC CHEMBL3923445 IC50 15.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@H](c4ccc(F)cc4)N4CCCC4)CC3)nc2c(F)c1OC CHEMBL4108762 IC50 15.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Nc1cn(C(N)=O)c2ccccc12)[C@H]1CC1(Cl)Cl CHEMBL4111212 IC50 15.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccccc12 CHEMBL4081888 IC50 15.0 nM
CC(C)Nc1cc(COc2ccccc2CC(=O)O)cc(-c2cccc([C@H](N)CO)c2)c1 CHEMBL4463116 IC50 15.0 nM
NC(=O)n1cc(CC(=O)N2C3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673872 IC50 16.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3678725 IC50 16.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3678728 IC50 16.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnccc12 CHEMBL3678841 IC50 16.0 nM
COc1cc2c(C(C)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2cc1OC CHEMBL3678860 IC50 16.0 nM
CO[C@H]1[C@@H](C(=O)NC2(c3cccc(Cl)c3F)CC2)N(C(=O)Cn2nc(C(N)=O)c3cnccc32)C[C@@H]1F CHEMBL3678873 IC50 16.0 nM
CCO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2cc(C(C)=O)c3cc(C)ncc32)C[C@@H]1F CHEMBL3678880 IC50 16.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2nc(C(C)=O)c3ccccc32)C[C@@H]1F CHEMBL3678893 IC50 16.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)/C=C/c4ccc(C#N)cc4)CC3)nc2c(F)c1OC CHEMBL3975396 IC50 16.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2ccc(OCc3ncccn3)cc12 CHEMBL4106747 IC50 16.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2C(C)(C)C2(Cl)Cl)c2ccc(OCc3ncccn3)cc12 CHEMBL4109257 IC50 16.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ncccc12 CHEMBL3941259 Kd 16.98 nM
COC(=O)c1cc(Cl)c(F)c(CNC(=O)[C@@H]2C[C@@H](F)CN2C(=O)Nc2cn(C(N)=O)c3ccccc23)c1 CHEMBL3668750 IC50 17.0 nM
NC(=O)n1cc(NC(=O)N2CCS[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCCO)ccc21 CHEMBL3673809 IC50 17.0 nM
NC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCc3nn[nH]n3)ccc12 CHEMBL3678802 IC50 17.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)[C@@H](O)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3678835 IC50 17.0 nM
CO[C@H]1[C@@H](C(=O)Nc2cccc(OC(F)(F)F)c2F)N(C(=O)Cn2nc(C(N)=O)c3ccncc32)C[C@@H]1F CHEMBL3678843 IC50 17.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnc(C)cc12 CHEMBL3678861 IC50 17.0 nM
Cc1nccc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NCc3cccc(Cl)c3F)c12 CHEMBL3678907 IC50 17.0 nM
CO[C@H]1[C@@H](C(=O)Nc2cccc(Br)c2F)N(C(=O)Cn2nc(C(N)=O)c3ccccc32)C[C@@H]1F CHEMBL3683731 IC50 17.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)c4cc5cc(F)cc(F)c5[nH]4)CC3)nc2c(F)c1OC CHEMBL3898919 IC50 17.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@@]2(CO)C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccccc21)[C@H]1CC1(Cl)Cl CHEMBL4115466 IC50 17.0 nM
COCCOc1ccc2c(c1)c(NC(=O)N1C[C@](C)(F)C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3668639 IC50 18.0 nM
CC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](CN(C)C)c2cccc(Cl)c2F)c2ccccc21 CHEMBL3673713 IC50 18.0 nM
COC(=O)c1ccc2c(C(C)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1 CHEMBL3678846 IC50 18.0 nM
CC(=O)c1nn(CC(=O)N2C[C@H](F)[C@@H](O)[C@H]2C(=O)NC2(c3cccc(Cl)c3F)CC2)c2cnccc12 CHEMBL3678849 IC50 18.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ncccc12 CHEMBL3678867 IC50 18.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2cc(C(=O)O)ccc12 CHEMBL3678936 IC50 18.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2cnccc12 CHEMBL3683712 IC50 18.0 nM
CN1CCC(N(C)C(=O)Nc2ccc3c(c2)c(C(N)=O)nn3CC(=O)N(CC(=O)NCc2cccc(Cl)c2F)C2CC2)CC1 CHEMBL5220885 Ki 18.5 nM
NC(=O)c1nn(CC(=O)N2CCS[C@H]2C(=O)Nc2cccc(Br)n2)c2ncccc12 CHEMBL3890777 Kd 18.85 nM
O=C(Nc1cccc(Br)n1)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1ncc2ccccc21 CHEMBL3951127 IC50 19.0 nM
NC(=O)n1cc(NC(=O)N2CCS[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ccccc21 CHEMBL3668649 IC50 19.0 nM
O=C(NCc1cccc(Cl)c1F)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1cc(C(=O)C(F)(F)F)c2ccccc21 CHEMBL3673920 IC50 19.0 nM
COC(=O)c1ccc2c(C(C)=O)cn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1 CHEMBL3678760 IC50 19.0 nM
CC(=O)c1nc(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)n2ccccc12 CHEMBL3678836 IC50 19.0 nM
CC(=O)c1nn(CC(=O)N2C[C@@H]3C[C@@H]3[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnc(C)cc12 CHEMBL3678839 IC50 19.0 nM
O=C(CO)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3678865 IC50 19.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)c2F)c2cnccc12 CHEMBL3678881 IC50 19.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2cc(C(C)=O)c3ccncc32)C[C@@H]1F CHEMBL3678894 IC50 19.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCC(F)=C(C)C)c2ccccc12 CHEMBL4114666 IC50 19.0 nM
CC1(C)[C@H](CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Nc2cn(C(N)=O)c3ccccc23)C1(Cl)Cl CHEMBL4108833 IC50 19.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@@H]2CC2(Cl)Cl)c2ccc(OCc3ncccn3)cc12 CHEMBL4110470 IC50 19.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2CNS(=O)(=O)c2cccc(Cl)c2F)c2ccccc21 CHEMBL3668622 IC50 20.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)NCc2ccc(Cl)s2)c2ccccc21 CHEMBL3668662 IC50 20.0 nM
NC(=O)n1cc(NC(=O)N2C[C@@](F)(CO)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668688 IC50 20.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2)c2ccccc21 CHEMBL3668690 IC50 20.0 nM
CO[C@@H]1CCN(C(=O)Nc2cn(C(N)=O)c3ccccc23)[C@@H]1C(=O)NCc1cccc(Cl)c1F CHEMBL3668693 IC50 20.0 nM
NC(=O)n1cc(NC(=O)N2CC[C@@H](F)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668697 IC50 20.0 nM
NC(=O)n1cc(NC(=O)N2N=CCC2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668708 IC50 20.0 nM
CN(C)C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Nc1cn(C(N)=O)c2ccccc12)c1cccc(Cl)c1F CHEMBL3673746 IC50 20.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(CC(=O)O)ccc21 CHEMBL3673806 IC50 20.0 nM
NC(=O)n1cc(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(F)ccc21 CHEMBL3673886 IC50 20.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(-c3c(F)cccc3Cl)c2)c2cnccc12 CHEMBL3678933 IC50 20.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)/C=C/c4ccc(C#N)cc4)C[C@@H]3C)nc2c(F)c1OC CHEMBL3890117 IC50 20.0 nM
CCC[C@H]1CN(C(=O)/C=C/c2ccc(C#N)cc2)CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1 CHEMBL3978495 IC50 20.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)c4cc5cc(C#N)ccc5[nH]4)CC3)nc2c(F)c1OC CHEMBL3953356 IC50 20.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccc(F)cc4)C[C@@H]3C)nc2c(F)c1OC CHEMBL3929496 IC50 20.0 nM
COCCN[C@H](CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)c(F)c3n2)CC1)c1ccc(F)cc1 CHEMBL4107253 IC50 20.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H]4CCCCN4)C[C@@H]3c3ccccc3)nc2c(F)c1OC CHEMBL3968840 IC50 20.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCC2CC(C)C2)c2ccc(OCc3ncccn3)cc12 CHEMBL4109806 IC50 20.0 nM
NCc1cccc(-c2cccc(C(=O)Nc3ccccc3CC(=O)O)n2)c1 CHEMBL4554970 IC50 20.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2cn1 CHEMBL3678864 IC50 21.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2c[n+]([O-])ccc12 CHEMBL3678917 IC50 21.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCCOC(F)(F)F)c2ccc(OCc3ncccn3)cc12 CHEMBL4110509 IC50 21.0 nM
CC1[C@H](CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(N)=O)c3ccncc32)C1(Cl)Cl CHEMBL4106662 IC50 21.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H]3C[C@H]3[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3639675 IC50 22.0 nM
NC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Br)c2F)c2ccccc12 CHEMBL3673906 IC50 22.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2cc(C(C)=O)c3cccnc32)C[C@@H]1F CHEMBL3678738 IC50 22.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccncc12 CHEMBL3678863 IC50 22.0 nM
CC(=O)NC[C@@]1(F)C[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 CHEMBL3668727 IC50 23.0 nM
C[C@@]12C[C@@H](C(=O)NCc3cccc(Cl)c3F)N(C(=O)Cn3nc(C(N)=O)c4ccncc43)[C@@H]1C2 CHEMBL3678888 IC50 23.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2nc(C(=O)O)ccc12 CHEMBL3678916 IC50 23.0 nM
NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccccc12 CHEMBL3683715 IC50 23.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(C(F)(F)F)c2F)c2ccccc21 CHEMBL4070311 IC50 23.0 nM
Cn1cc(-c2cc(COc3ccccc3CC(=O)O)cc(-c3cccc(CC(N)=O)c3F)c2)cn1 CHEMBL4249566 IC50 23.0 nM
CC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnccc12 CHEMBL4112048 IC50 24.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3CC3C[C@H]2C(=O)Nc2cccc(C(F)(F)F)c2F)c2ccccc21 CHEMBL3668724 IC50 24.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(CC(=O)O)cc21 CHEMBL3673807 IC50 24.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2cc(C(C)=O)c3cc(C)ncc32)C[C@@H]1F CHEMBL3678871 IC50 24.0 nM
CO[C@H]1[C@@H](C(=O)N[C@H](C)c2cccc(Cl)c2F)N(C(=O)Cn2nc(C(N)=O)c3ccncc32)C[C@@H]1F CHEMBL3678877 IC50 24.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ccc(OCc3ncccn3)cc12 CHEMBL3678929 IC50 24.0 nM
CC(C)=C(F)CNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Nc1cn(C(N)=O)c2ccccc12 CHEMBL4114744 IC50 24.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2cnccc12 CHEMBL4113305 IC50 24.0 nM
NC(=O)n1cc(NC(=O)N2C[C@@H](N)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673894 IC50 25.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2ccccc2)c2ccccc21 CHEMBL3663969 IC50 25.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)c2)c2ccccc21 CHEMBL3668657 IC50 25.0 nM
COC(=O)[C@H]1C[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 CHEMBL3668707 IC50 25.0 nM
NC(=O)n1cc(NC(=O)N2CC[C@@H](O)[C@H]2C(=O)NCc2ccc(Cl)s2)c2ccccc21 CHEMBL3668765 IC50 25.0 nM
NC(=O)n1cc(NC(=O)N2N=CCC2C(=O)NCc2cccc(Cl)c2)c2ccccc21 CHEMBL3673792 IC50 25.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(OCCO)cc21 CHEMBL3673824 IC50 25.0 nM
NC[C@@]1(F)C[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 CHEMBL3673838 IC50 25.0 nM
NC(=O)n1cc(CC(=O)N2CCS[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673876 IC50 25.0 nM
O=C(CO)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3678774 IC50 25.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(O)ccc12 CHEMBL3678796 IC50 25.0 nM
CO[C@H]1[C@@H](C(=O)N[C@H](C)c2cccc(Cl)c2F)N(C(=O)Cn2nc(C(N)=O)c3cccnc32)C[C@@H]1F CHEMBL3678856 IC50 25.0 nM
CO[C@H]1[C@@H](C(=O)NC2(c3cccc(Cl)c3F)CC2)N(C(=O)Cn2nc(C(N)=O)c3cccnc32)C[C@@H]1F CHEMBL3678872 IC50 25.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(C(F)(F)F)n2)c2cnccc12 CHEMBL3678943 IC50 25.0 nM
C[C@@H](N)c1cccc(-c2cccc(COc3ccccc3CC(=O)O)c2)c1 CHEMBL4516604 IC50 25.0 nM
NC[C@@]1(F)C[C@@H](C(=O)NCc2c(F)ccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 CHEMBL3673840 IC50 26.0 nM
NC(=O)n1cc(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673874 IC50 26.0 nM
CO[C@H]1[C@@H](C(=O)N[C@H](C)c2cccc(Cl)c2F)N(C(=O)Cn2nc(C(C)=O)c3cccnc32)C[C@@H]1F CHEMBL3678838 IC50 26.0 nM
CO[C@H]1[C@@H](C(=O)N[C@H](C)c2cccc(Cl)c2F)N(C(=O)Cn2cc(C(C)=O)c3ccccc32)C[C@@H]1F CHEMBL3678788 IC50 27.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(-c3ccccc3F)c2F)c2cnccc12 CHEMBL3678897 IC50 27.0 nM
CCc1cc2c(C(N)=O)nn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)Nc3cccc(OC(F)(F)F)c3F)c2cn1 CHEMBL3678926 IC50 27.0 nM
CCc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)N[C@H](C)[C@H]3CC3(Cl)Cl)c2cn1 CHEMBL4111875 IC50 27.0 nM
CO[C@H]1[C@@H](C(=O)NC[C@H]2CC2(Cl)Cl)N(C(=O)Cn2nc(C(N)=O)c3ccc(C)cc32)C[C@@H]1F CHEMBL4113768 IC50 27.0 nM
NC(=O)c1nn(CC(=O)N(CC(=O)NCc2cccc(Cl)c2F)C2CC2)c2cc(C(=O)O)ccc12 CHEMBL5219696 IC50 27.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCCN3CCCC3)ccc21 CHEMBL3673817 IC50 28.0 nM
NC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(Cl)ccc12 CHEMBL3673916 IC50 28.0 nM
CC(=O)c1cn(CC(=O)N2C[C@@](F)(CN)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3678823 IC50 28.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(-c3nnn[nH]3)ccc12 CHEMBL3678833 IC50 28.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)[C@@H](F)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3683755 IC50 28.0 nM
NC(=O)c1nn(CC(=O)N(CC(=O)NCc2cccc(Cl)c2F)C2CC2)c2ccc(NC(=O)N3CCN(C4CC4)CC3)cc12 CHEMBL5220461 IC50 28.0 nM
NC(=O)n1cc(NC(=O)N2CC[C@H](F)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668715 IC50 29.0 nM
C[C@@]1(F)C[C@@H](C(=O)N[C@H](CCO)c2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 CHEMBL3668735 IC50 29.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cc(Br)cc(C(=O)O)c2)c2ccccc21 CHEMBL3673771 IC50 29.0 nM
C[C@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccncc21)c1cccc(Cl)c1F CHEMBL3678911 IC50 29.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)N[C@H](CO)c2cccc(Cl)c2F)c2ccccc21 CHEMBL3663972 IC50 30.0 nM
NC(=O)n1cc(NC(=O)N2CCC[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668677 IC50 30.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)Nc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668683 IC50 30.0 nM
CC(=O)n1cc(NC(=O)N2[C@H](C(=O)NCc3cccc(Cl)c3F)C[C@@]3(CO)C[C@@H]23)c2ccccc21 CHEMBL3912654 IC50 30.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cc(C(=O)O)cc(Br)c2F)c2ccccc21 CHEMBL3673774 IC50 30.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCCn3ccnc3)ccc21 CHEMBL3673818 IC50 30.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)NCc2ccccc2F)c2cc(OCC(=O)O)ccc21 CHEMBL3673820 IC50 30.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(-c3ncccc3F)c2F)c2ccccc12 CHEMBL3678899 IC50 30.0 nM
CC[C@H]1CN(C(=O)C[C@@H](N)c2ccc(F)cc2)CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1 CHEMBL3973437 IC50 30.0 nM
COc1cc2nc(N3CCN(C(=O)C[C@@H](N)c4ccc(F)cc4)CC3)nc(N)c2c(F)c1OC CHEMBL4109043 IC50 30.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](NCC(F)(F)F)c4ccc(F)cc4)CC3)nc2c(F)c1OC CHEMBL4110121 IC50 30.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](NC(C)C)c4ccc(F)cc4)CC3)nc2c(F)c1OC CHEMBL4107492 IC50 30.0 nM
N[C@H](CCO)c1cccc(-c2cccc(COc3ccccc3CC(=O)O)c2)c1 CHEMBL4546264 IC50 30.0 nM
NC(=O)c1nn(CC(=O)N(CC(=O)NCc2cccc(Cl)c2F)C2CC2)c2ccc(NC(=O)N3CCN(Cc4ccc(F)cc4)CC3)cc12 CHEMBL5219562 IC50 30.0 nM
COCCN(C)c1cc(Cl)c(F)c(CNC(=O)[C@@H]2C[C@@H](F)CN2C(=O)Nc2cn(C(N)=O)c3ccccc23)c1 CHEMBL3663988 IC50 31.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)[C@@H](N)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673844 IC50 31.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(OC(F)(F)F)cc12 CHEMBL3678757 IC50 31.0 nM
COc1ccc2c(c1)c(C(C)=O)cn2CC(=O)N1C[C@H](F)C[C@H]1C(=O)NCc1cccc(Cl)c1F CHEMBL3678805 IC50 31.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(OC(F)(F)F)c3F)c2c(C)n1 CHEMBL3678928 IC50 31.0 nM
CN1CCN(c2cc(Cl)c(F)c(CNC(=O)[C@@H]3C[C@@H](F)CN3C(=O)Nc3cn(C(N)=O)c4ccccc34)c2)CC1 CHEMBL3663974 IC50 32.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(CCO)cc21 CHEMBL3673813 IC50 32.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](C)c2cccc(Cl)c2F)c2cnccc12 CHEMBL3683751 IC50 32.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2ccccc12 CHEMBL4109987 IC50 32.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2ccc(OCc3ncccc3F)cc12 CHEMBL4110916 IC50 32.0 nM
NC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3673901 IC50 33.0 nM
COC(=O)c1cc(Cl)c(F)c(CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2cc(C(N)=O)c3ccccc32)c1 CHEMBL3673905 IC50 33.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnccc12 CHEMBL3678768 IC50 33.0 nM
CC(C)=C(F)CNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccc(Cl)cc21 CHEMBL3965945 IC50 33.0 nM
COC[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1cc(C(C)=O)c2cccnc21)c1cccc(Cl)c1F CHEMBL3678751 IC50 34.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@@H](F)CN1C(=O)Cn1nc(C(N)=O)c2ccncc21)c1cccc(Cl)c1F CHEMBL3678903 IC50 34.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ncccc12 CHEMBL3683726 IC50 34.0 nM
NC(=O)c1nn(CC(=O)N(CC(=O)NCc2cccc(Cl)c2F)C2CC2)c2ccc(NC(=O)N3CCCC(F)(F)C3)cc12 CHEMBL5220104 IC50 34.0 nM
NC(=O)c1nn(CC(=O)N(CC(=O)NCc2cccc(Cl)c2F)C2CC2)c2ccc(NC(=O)NC3CCCCC3)cc12 CHEMBL5218975 IC50 34.0 nM
NC(=O)n1cc(NC(=O)N2CCS[C@H]2C(=O)NCc2cccc(Cl)c2)c2ccccc21 CHEMBL3668681 IC50 35.0 nM
NC(=O)n1cc(NC(=O)N2CCS[C@H]2C(=O)NCc2ccc(Cl)s2)c2ccccc21 CHEMBL3673725 IC50 35.0 nM
NC(=O)n1cc(NC(=O)N2C[C@@H](O)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673763 IC50 35.0 nM
NC(=O)n1cc(NC(=O)N2NCCC2C(=O)NCc2cccc(Cl)c2)c2ccccc21 CHEMBL3673862 IC50 35.0 nM
CC(C)=C(F)CNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccccc21 CHEMBL4114698 IC50 35.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](C)[C@H]2CC2(Cl)Cl)c2cnccc12 CHEMBL4107609 IC50 35.0 nM
CC1[C@H](CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(N)=O)c3ccccc32)C1(Cl)Cl CHEMBL4113156 IC50 35.0 nM
COc1ccc2c(C(N)=O)cn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1 CHEMBL3673924 IC50 36.0 nM
COc1ccc2c(C(C)=O)cn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1 CHEMBL3673925 IC50 36.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cc(-c3nnn[nH]3)cc(Cl)c2F)c2ccccc12 CHEMBL3678743 IC50 36.0 nM
CC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnc(C)cc12 CHEMBL3678840 IC50 36.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2nc(C(C)=O)c3cnccc32)C[C@@H]1F CHEMBL3678844 IC50 36.0 nM
CO[C@H]1[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2nc(C(N)=O)c3cnccc32)C[C@@H]1F CHEMBL3678876 IC50 36.0 nM
C[C@@]12C[C@@H](C(=O)Nc3cccc(OC(F)(F)F)c3F)N(C(=O)Cn3nc(C(N)=O)c4ccccc43)[C@@H]1C2 CHEMBL3683713 IC50 36.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2cnccc12 CHEMBL4109745 IC50 36.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cc(-c3nnn[nH]3)cc(Cl)c2F)c2ccccc12 CHEMBL3678739 IC50 37.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(CO)ccc12 CHEMBL3678820 IC50 37.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2nc(Br)cs2)c2ccccc12 CHEMBL3683718 IC50 37.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCC(F)=C(C)C)c2cnccc12 CHEMBL4114667 IC50 37.0 nM
CC(C)(C)OC(=O)COc1ccc2c(c1)c(NC(=O)N1[C@@H]3C[C@@H]3C[C@H]1C(=O)NCc1ccccc1F)cn2C(N)=O CHEMBL3673819 IC50 38.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ncccc12 CHEMBL3678765 IC50 38.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(O)ccc12 CHEMBL3678801 IC50 38.0 nM
CO[C@H]1[C@@H](C(=O)Nc2cccc(OC(F)(F)F)c2F)N(C(=O)Cn2nc(C(N)=O)c3ccccc32)C[C@@H]1F CHEMBL3678842 IC50 38.0 nM
CCc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(OC(F)(F)F)c3F)c2cn1 CHEMBL3678923 IC50 38.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(O)cc12 CHEMBL3678797 IC50 39.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(-c3nnn[nH]3)ccc12 CHEMBL3678834 IC50 39.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@@H](F)CN1C(=O)Cn1nc(C(N)=O)c2ccccc21)[C@H]1CC1(Cl)Cl CHEMBL4110965 IC50 39.0 nM
NC(=O)n1cc(NC(=O)N2CC[C@@H](N)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673846 IC50 40.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnccc12 CHEMBL3678770 IC50 40.0 nM
COC[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cc1nc(C(C)=O)c2ccccn12)c1cccc(Cl)c1F CHEMBL3678891 IC50 40.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccsc4)CC3)nc2c(F)c1OC CHEMBL4115080 IC50 40.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4cccc(C#N)c4)CC3)nc2c(F)c1OC CHEMBL4115621 IC50 40.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccc(F)cc4)CC3)nc2c(F)c1OC CHEMBL4109775 IC50 40.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccc(C(F)(F)F)cc4)C[C@@H]3C)nc2c(F)c1OC CHEMBL3957065 IC50 40.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@H](c4ccc(F)cc4)N(C)C)CC3)nc2c(F)c1OC CHEMBL4111694 IC50 40.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](NC(CF)CF)c4ccc(F)cc4)CC3)nc2c(F)c1OC CHEMBL4110860 IC50 40.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)N[C@H](C)[C@H]3CC3(Cl)Cl)c2cn1 CHEMBL4111771 IC50 40.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2cc(Cl)ccc12 CHEMBL4112103 IC50 40.0 nM
CC(C)c1cc(COc2ccccc2CC(=O)O)cc(-c2ccc3c(c2)[C@H](N)CO3)c1 CHEMBL4643449 IC50 40.0 nM
CC(C)(C#N)c1cc(COc2ccccc2CC(=O)O)cc(-c2ccc3c(c2)[C@H](N)CO3)c1 CHEMBL4636415 IC50 40.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](CO)c2cccc(Br)c2)c2ccccc21 CHEMBL3668723 IC50 41.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)N[C@H](CO)c2cccc(Cl)c2F)c2ccccc12 CHEMBL3678736 IC50 41.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(CC(=O)O)ccc12 CHEMBL3678812 IC50 41.0 nM
Cc1nccc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)N[C@H](C)[C@H]3CC3(Cl)Cl)c12 CHEMBL4108917 IC50 41.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2ccc(OCc3ncccn3)cc12 CHEMBL4114336 IC50 41.0 nM
O=C(CO)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3678781 IC50 42.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(C(=N)N(C)C)cc12 CHEMBL3678831 IC50 42.0 nM
NC(=O)n1cc(CC(=O)N2C[C@H](F)[C@@H](N)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673892 IC50 43.0 nM
CCc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NCC(F)=C(C)C)c2cn1 CHEMBL4115680 IC50 43.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)N[C@H](C)[C@H]3CC3(Cl)Cl)c2c(C)n1 CHEMBL4115590 IC50 43.0 nM
C[C@@]1(F)C[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Cn2cc(C(=O)C(F)(F)F)c3ccccc32)C1 CHEMBL3678772 IC50 44.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(C(F)(F)F)n2)c2cnccc12 CHEMBL3678942 IC50 44.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)Nc2cccc(Br)c2)c2ccccc21 CHEMBL3668655 IC50 45.0 nM
C[C@H](NC(=O)[C@@H]1[C@H](O)CCN1C(=O)Nc1cn(C(N)=O)c2ccccc12)c1cccc(Cl)c1F CHEMBL3673796 IC50 45.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2ccccc2F)c2cc(O)ccc21 CHEMBL3673803 IC50 45.0 nM
CC(=O)c1cn(CC(=O)N2[C@H](C(=O)NCc3cccc(Cl)c3F)C[C@@]3(CO)C[C@@H]23)c2ncccc12 CHEMBL3906096 IC50 45.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2cc[n+]([O-])cc21)c1cccc(Cl)c1F CHEMBL3678918 IC50 45.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)c2)c2ccccc21 CHEMBL4061643 IC50 45.0 nM
CC(=O)c1cn(CC(=O)N2C[C@](C)(F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(C(=O)O)ccc12 CHEMBL3678815 IC50 46.0 nM
Cc1nccc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(OC(F)(F)F)c3F)c12 CHEMBL3678927 IC50 46.0 nM
CC1CCCC(CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 CHEMBL4114113 IC50 46.0 nM
C[C@@H]1CC[C@H](CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(N)=O)c3ccccc32)C1 CHEMBL4106904 IC50 46.0 nM
CCOC(=O)c1cc(Br)c(F)c(NC(=O)[C@@H]2C[C@@H](F)CN2C(=O)Nc2cn(C(N)=O)c3ccccc23)c1 CHEMBL3673765 IC50 47.0 nM
NC(=O)n1cc(CC(=O)N2[C@H](C(=O)NCc3cccc(Cl)c3F)C[C@@]3(CO)C[C@@H]23)c2ccccc21 CHEMBL3969205 IC50 47.0 nM
Cc1cc2c(cn1)c(C(N)=O)nn2CC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)NCc1cccc(Cl)c1F CHEMBL3678866 IC50 47.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2)c2ccccc21 CHEMBL3668698 IC50 48.0 nM
COc1cnc2c(c1)c(C(C)=O)cn2CC(=O)N1[C@@H]2C[C@@H]2C[C@H]1C(=O)NCc1cccc(Cl)c1F CHEMBL3673919 IC50 50.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4cccc(F)c4)CC3)nc2c(F)c1OC CHEMBL4108466 IC50 50.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccc(C(F)F)cc4)CC3)nc2c(F)c1OC CHEMBL4113394 IC50 50.0 nM
COc1cc2c(N)nc(N3C[C@@H](C)N(C(=O)C[C@@H](N)c4ccc(F)cc4)C[C@@H]3C)nc2c(F)c1OC CHEMBL4107830 IC50 50.0 nM
CN[C@H](CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)c(F)c3n2)CC1)c1ccccc1 CHEMBL4106761 IC50 50.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2)c2ccccc21 CHEMBL4065529 IC50 50.0 nM
CC1(C)COc2c(COc3ccccc3CC(=O)O)cc(-c3ccc4c(c3)[C@H](N)CO4)cc21 CHEMBL4635912 IC50 50.0 nM
NC(=O)n1cc(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](CO)c2cccc(Cl)c2F)c2ccccc21 CHEMBL3673875 IC50 51.0 nM
COC(=O)c1cc(Cl)c(F)c(CNC(=O)[C@@H]2C[C@@H](F)CN2C(=O)Cn2cc(C(C)=O)c3ccccc32)c1 CHEMBL3678741 IC50 51.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCc3ccccc3)ccc12 CHEMBL3678752 IC50 51.0 nM
CO[C@H]1[C@@H](C(=O)NC[C@H]2CC2(Cl)Cl)N(C(=O)Cn2nc(C(N)=O)c3ccc(Cl)cc32)C[C@@H]1F CHEMBL4111361 IC50 51.0 nM
C[C@@]1(F)C[C@@H](C(=O)N[C@H](CO)c2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 CHEMBL3668745 IC50 52.0 nM
COC(=O)c1ccc2c(C(C)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(OC(F)(F)F)c3F)c2c1 CHEMBL3678921 IC50 52.0 nM
CC1(C)[C@H](CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(N)=O)c3ccccc32)C1(Cl)Cl CHEMBL4106748 IC50 52.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2)c2ccccc21 CHEMBL3639726 IC50 53.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)[C@@H](OCCN(C)C)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3678848 IC50 53.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Cl)c2F)c2ccccc12 CHEMBL3678941 IC50 53.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2ncccc12 CHEMBL4109044 IC50 53.0 nM
CC1CCC(CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(N)=O)c3ccccc32)C1 CHEMBL4106688 IC50 53.0 nM
CNC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668637 IC50 54.0 nM
CNC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](COC)c2cccc(Cl)c2F)c2ccccc21 CHEMBL3668776 IC50 54.0 nM
COC(=O)c1ccc2c(C(C)=O)cn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1 CHEMBL3678744 IC50 54.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cc(C(=O)O)cc(Cl)c2F)c2ccccc12 CHEMBL3678821 IC50 54.0 nM
NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ccccc12 CHEMBL3678919 IC50 54.0 nM
NC(=O)c1nn(CC(=O)N(CC(=O)NCc2cccc(Cl)c2F)C2CC2)c2cc(O)ccc12 CHEMBL5220699 IC50 54.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(F)c2F)c2ccccc21 CHEMBL3663981 IC50 55.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2CNS(=O)(=O)c2cccc(Br)c2)c2ccccc21 CHEMBL3668620 IC50 55.0 nM
COC(=O)c1cc(Br)cc(NC(=O)[C@@H]2C[C@@H](F)CN2C(=O)Nc2cn(C(N)=O)c3ccccc23)c1 CHEMBL3668660 IC50 55.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cc(Br)cc(C(=O)O)c2)c2ccccc21 CHEMBL3668666 IC50 55.0 nM
CC(C)c1cccc(NC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Nc2cn(C(N)=O)c3ccccc23)c1 CHEMBL3673717 IC50 55.0 nM
COc1ccc2c(c1)c(NC(=O)N1[C@@H]3C[C@@H]3C[C@H]1C(=O)Nc1cc(Br)cc(C(=O)O)c1)cn2C(N)=O CHEMBL3673773 IC50 55.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC2(c3cccc(Cl)c3F)COC2)c2ncccc12 CHEMBL3678847 IC50 55.0 nM
NC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCC(=O)O)ccc12 CHEMBL3678810 IC50 56.0 nM
CC(C)=C(F)CNC(=O)[C@@H]1C[C@@H](F)CN1C(=O)Cn1nc(C(N)=O)c2ccccc21 CHEMBL4114771 IC50 56.0 nM
NC(=O)c1nn(CC(=O)N2[C@H](C(=O)NC[C@H]3CC3(Cl)Cl)C[C@@]3(CO)C[C@@H]23)c2ccccc12 CHEMBL4114080 IC50 56.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2)c2cc(OCCO)ccc21 CHEMBL3673810 IC50 57.0 nM
CN(C)CCOc1ccc2c(c1)c(NC(=O)N1[C@@H]3C[C@@H]3C[C@H]1C(=O)NCc1cccc(Cl)c1F)cn2C(N)=O CHEMBL3673816 IC50 57.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](CCO)c2cccc(Cl)c2F)c2ccccc12 CHEMBL3673929 IC50 57.0 nM
C[Si](C)(C)CCNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Nc1cn(C(N)=O)c2ccccc12 CHEMBL4109454 IC50 57.0 nM
NC(=O)n1cc(NC(=O)N2C[C@@H](N)[C@H](F)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673859 IC50 58.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OC(F)(F)F)ccc12 CHEMBL3678727 IC50 58.0 nM
CO[C@H]1[C@@H](C(=O)N[C@H](C)c2cccc(Cl)c2F)N(C(=O)Cn2nc(C(N)=O)c3cnccc32)C[C@@H]1F CHEMBL3678878 IC50 58.0 nM
CC(C)(C)CCNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Nc1cn(C(N)=O)c2ccccc12 CHEMBL4112611 IC50 58.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2ccc(O)cc12 CHEMBL4106696 IC50 58.0 nM
NC(=O)n1cc(NC(=O)N2CC3CC3[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3668642 IC50 59.0 nM
CO[C@H]1[C@@H](C(=O)NCC(F)=C(C)C)N(C(=O)Cn2nc(C(N)=O)c3ccccc32)C[C@@H]1F CHEMBL3923471 IC50 59.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2CNS(=O)(=O)c2ccc(Cl)s2)c2ccccc21 CHEMBL3668623 IC50 60.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ncccc12 CHEMBL3673908 IC50 60.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(O)cc12 CHEMBL3678799 IC50 60.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccc(Br)cc4)CC3)nc2c(F)c1OC CHEMBL4107708 IC50 60.0 nM
CCC[C@H]1CN(C(=O)C[C@@H](N)c2ccc(C(F)(F)F)cc2)CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1 CHEMBL3967146 IC50 60.0 nM
COc1cc2c(N)nc(N3C[C@@H](C)N(C(=O)C[C@@H](N)c4ccccc4)C[C@@H]3C)nc2c(F)c1OC CHEMBL4113287 IC50 60.0 nM
CC(C)c1cc(-c2ccc3c(c2)[C@H](N)CO3)cc([C@@H]2CNc3cccc(CC(=O)O)c3O2)c1 CHEMBL4642845 IC50 60.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2cnccc12 CHEMBL3678935 IC50 61.0 nM
CC(C)(C)CCNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccccc21 CHEMBL4114643 IC50 61.0 nM
COC[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1cc(C(C)=O)c2ccncc21)c1cccc(Cl)c1F CHEMBL3678753 IC50 62.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(C(=O)O)ccc12 CHEMBL3678853 IC50 62.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)F)c2F)c2ccccc12 CHEMBL3678939 IC50 62.0 nM
C[C@H]1C[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 CHEMBL3668689 IC50 63.0 nM
CC(C)=C(F)CNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccnc(C)c21 CHEMBL4114734 IC50 63.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccncc12 CHEMBL3678742 IC50 64.0 nM
NC(=O)c1nn(CC(=O)N2[C@H](C(=O)Nc3cccc(OC(F)(F)F)c3F)C[C@@]3(CO)C[C@@H]23)c2ccccc12 CHEMBL3979457 IC50 64.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccccc21)C1CCCCC1 CHEMBL4107919 IC50 64.0 nM
NC(=O)n1cc(NC(=O)N2C[C@@H](N)C[C@H]2C(=O)NCc2ccc(Cl)s2)c2ccccc21 CHEMBL3668580 IC50 65.0 nM
COc1ccc2c(NC(=O)N3C4CC4C[C@H]3C(=O)NCc3cccc(Cl)c3F)cn(C(N)=O)c2c1 CHEMBL3668722 IC50 65.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cc(Cl)cc(C(=O)O)c2)c2ccccc21 CHEMBL3673770 IC50 65.0 nM
C[Si](C)(C)CCNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2cccnc21 CHEMBL4108371 IC50 65.0 nM
CC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(OC(F)F)cc21 CHEMBL3673799 IC50 66.0 nM
NC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccccc12 CHEMBL3683729 IC50 66.0 nM
NC(=O)c1nn(CC(=O)N2CCC[C@H]2C(=O)Nc2cccc(Br)n2)c2ccccc12 CHEMBL5218654 IC50 67.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cc(Br)cc(-c3nnn[nH]3)c2)c2ccccc21 CHEMBL3673775 IC50 68.0 nM
CNC[C@@]1(F)C[C@@H](C(=O)NCc2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 CHEMBL3673853 IC50 68.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)N[C@H](C)c3cccc(Cl)c3F)c2cn1 CHEMBL3678904 IC50 68.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCCC(C)(C)C)c2cnccc12 CHEMBL4109940 IC50 68.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cc(-c3nnn[nH]3)cc(Cl)c2F)c2ccccc21 CHEMBL3673777 IC50 69.0 nM
COC(=O)Cc1ccc2c(C(C)=O)cn(CC(=O)N3C[C@H](F)C[C@H]3C(=O)NCc3cccc(Cl)c3F)c2c1 CHEMBL3678767 IC50 69.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cncc(Cl)c2)c2ccccc21 CHEMBL3668743 IC50 70.0 nM
C=CCOc1ccc2c(NC(=O)N3C4CC4C[C@H]3C(=O)NCc3cccc(Cl)c3F)cn(C(N)=O)c2c1 CHEMBL3673743 IC50 70.0 nM
COC(=O)COc1ccc2c(NC(=O)N3C4CC4C[C@H]3C(=O)NCc3cccc(Cl)c3F)cn(C(N)=O)c2c1 CHEMBL3673823 IC50 70.0 nM
CC(=O)c1nc(CC(=O)N2[C@H](C(=O)NCc3cccc(Cl)c3F)C[C@@]3(CO)C[C@@H]23)n2ccccc12 CHEMBL3920170 IC50 70.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)c4cc5cc(F)ccc5[nH]4)CC3)nc2c(F)c1OC CHEMBL3914430 IC50 70.0 nM
COCCOc1c(OC)cc2c(N)nc(N3CCN(C(=O)c4cc5cc(Cl)ccc5[nH]4)C[C@@H]3C)nc2c1F CHEMBL3952335 IC50 70.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccc(C)cc4)CC3)nc2c(F)c1OC CHEMBL4110298 IC50 70.0 nM
COCCOc1c(OC)cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccc(C#N)cc4)C[C@@H]3C)nc2c1F CHEMBL3941522 IC50 70.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@@H]2C(C)(C)C2(Cl)Cl)c2ccc(OCc3ncccn3)cc12 CHEMBL4108360 IC50 70.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CCC[C@@H](C)C2)c2cnccc12 CHEMBL4115010 IC50 70.0 nM
CC(=O)c1cn(CC(=O)N2C[C@](C)(F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12 CHEMBL3678729 IC50 71.0 nM
NC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(O)cc12 CHEMBL3678795 IC50 71.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ncccc12 CHEMBL3678922 IC50 71.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](C)C2CCCCC2)c2cnccc12 CHEMBL4109542 IC50 71.0 nM
CC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@H]2CC2(Cl)Cl)c2ccc(CCc3ncccn3)cc12 CHEMBL4110759 IC50 71.0 nM
CC(=O)c1cn(CC(=O)N2C[C@](C)(F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ncccc12 CHEMBL3678748 IC50 72.0 nM
CC(C)=C(F)CNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2cc(C)ncc21 CHEMBL4114725 IC50 74.0 nM
C[C@H]1CC[C@@H](CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(N)=O)c3ccccc32)C1 CHEMBL3953066 IC50 74.0 nM
Cc1ccc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NC[C@H]3CC3(Cl)Cl)c2c1 CHEMBL4111392 IC50 74.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2CNS(=O)(=O)c2cccc(Cl)c2)c2ccccc21 CHEMBL3668619 IC50 75.0 nM
NC(=O)n1cc(NC(=O)N2C3CC3C[C@H]2C(=O)NCc2cccc(C(F)(F)F)c2F)c2ccccc21 CHEMBL3668767 IC50 75.0 nM
CC1(C)CC[C@@H](C(=O)NCc2cccc(Cl)c2F)N1C(=O)Nc1cn(C(N)=O)c2ccccc12 CHEMBL3673734 IC50 75.0 nM
NC(=O)n1cc(CC(=O)N2CCS[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCCO)ccc21 CHEMBL3673888 IC50 75.0 nM
NC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OC(F)F)ccc12 CHEMBL3678746 IC50 75.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(C3CC3)c2F)c2ccccc12 CHEMBL3678887 IC50 75.0 nM
O=C(Nc1cccc(Br)n1)[C@@H]1SCCN1C(=O)Cn1ncc2ccccc21 CHEMBL3924715 IC50 77.0 nM
CCc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(Br)c3F)c2cn1 CHEMBL3678884 IC50 77.0 nM
NC(=O)c1nn(CC(=O)N(CC(=O)NCc2cccc(Cl)c2F)C2CC2)c2cc(CO)ccc12 CHEMBL5220812 IC50 77.0 nM
NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2ccccc2)c2ccccc21 CHEMBL3668764 IC50 78.0 nM
NC(=O)c1nn(CC(=O)N2CCS[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cnccc12 CHEMBL3678870 IC50 78.0 nM
CC(C)=C(F)CNC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccncc21 CHEMBL4114724 IC50 78.0 nM
C[C@@H](NC(=O)[C@@H]1C[C@H]2C[C@H]2N1C(=O)Nc1cn(C(N)=O)c2ccccc12)C1CCCCC1 CHEMBL4107841 IC50 78.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCc3nn[nH]n3)ccc12 CHEMBL3678804 IC50 79.0 nM
CC(=O)c1nc(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)N[C@H](CO)c2cccc(Cl)c2F)n2ccccc12 CHEMBL3678857 IC50 79.0 nM
CCc1cccc(NC(=O)[C@@H]2CC3CC3N2C(=O)Nc2cn(C(N)=O)c3ccccc23)n1 CHEMBL3668665 IC50 80.0 nM
COc1cc(F)c(F)c(CNC(=O)[C@@H]2SCCN2C(=O)Nc2cn(C(N)=O)c3ccccc23)c1 CHEMBL3668741 IC50 80.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)c4cc5cc(O)ccc5[nH]4)CC3)nc2c(F)c1OC CHEMBL3925732 IC50 80.0 nM
CN[C@H](CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)c(F)c3n2)CC1)C1CCCCC1 CHEMBL4110147 IC50 80.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@H](c4ccccc4)N(C)C)CC3)nc2c(F)c1OC CHEMBL4113998 IC50 80.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H]4CCCN4)C[C@@H]3c3ccccc3)nc2c(F)c1OC CHEMBL3942752 IC50 80.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccncc12 CHEMBL3683727 IC50 81.0 nM
CNC(=O)n1cc(NC(=O)N2[C@H](C(=O)NCc3cccc(Cl)c3F)S[C@@]3(CO)C[C@@H]23)c2ccccc21 CHEMBL4106561 IC50 83.0 nM
NC(=O)n1cc(NC(=O)N2CCS[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2)c2ccccc21 CHEMBL3668773 IC50 83.0 nM
CC(C)(C)OC(=O)Nc1ccc2c(c1)c(C(N)=O)nn2CC(=O)N(CC(=O)NCc1cccc(Cl)c1F)C1CC1 CHEMBL5220843 IC50 84.0 nM
NC(=O)n1cc(NC(=O)N2C[C@@H](N)C[C@H]2C(=O)NCc2c(F)ccc(Cl)c2F)c2ccccc21 CHEMBL3668576 IC50 85.0 nM
NC(=O)n1cc(NC(=O)N2CC[C@@H](O)[C@H]2C(=O)NCc2cccc(Cl)c2)c2ccccc21 CHEMBL3668684 IC50 85.0 nM
NC(=O)n1cc(NC(=O)N2CCS[C@H]2C(=O)Nc2cncc(Br)c2)c2ccccc21 CHEMBL3673753 IC50 85.0 nM
C[C@@H]1CC[C@@H](C(=O)NCc2cccc(Cl)c2F)N1C(=O)Nc1cn(C(N)=O)c2ccccc12 CHEMBL3673781 IC50 85.0 nM
NC(=O)n1cc(CC(=O)N2C3CC3C[C@H]2C(=O)NCc2ccc(Cl)s2)c2ccccc21 CHEMBL3673882 IC50 85.0 nM
NC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCCO)ccc12 CHEMBL3678811 IC50 85.0 nM
CC1[C@@H](CNC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(N)=O)c3ccncc32)C1(Cl)Cl CHEMBL4109325 IC50 85.0 nM
CC(C)(C)NC(=O)Nc1ccc2c(c1)c(C(N)=O)nn2CC(=O)N(CC(=O)NCc1cccc(Cl)c1F)C1CC1 CHEMBL5220585 IC50 87.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ccccc12 CHEMBL3683752 IC50 88.0 nM
CO[C@H]1[C@@H](C(=O)NCCC(C)(C)C)N(C(=O)Cn2nc(C(C)=O)c3ccccc32)C[C@@H]1F CHEMBL3964786 IC50 88.0 nM
NC[C@@]1(F)C[C@@H](C(=O)NCc2c(F)ccc(Cl)c2F)N(C(=O)Cc2cn(C(N)=O)c3ccccc23)C1 CHEMBL3673897 IC50 89.0 nM
NC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(Br)c(F)cc12 CHEMBL3673904 IC50 89.0 nM
NC(=O)c1nn(CC(=O)N(CC(=O)NCc2cccc(Cl)c2F)C2CC2)c2ccc(CO)cc12 CHEMBL5219286 IC50 89.0 nM
CCN(CC)CCNC(=O)Nc1ccc2c(c1)c(C(N)=O)nn2CC(=O)N(CC(=O)NCc1cccc(Cl)c1F)C1CC1 CHEMBL5219487 IC50 89.0 nM
NC(=O)n1cc(NC(=O)N2C[C@@H](N)C[C@H]2C(=O)NCc2cccc(Br)c2)c2ccccc21 CHEMBL3664000 IC50 90.0 nM
NC(=O)n1cc(CC(=O)N2C[C@@](F)(CO)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673877 IC50 90.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(Br)c3F)c2cn1 CHEMBL3678883 IC50 90.0 nM
Cc1cc2c(C(N)=O)nn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)Nc3cccc(OC(F)(F)F)c3F)c2cn1 CHEMBL3678934 IC50 90.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC/C(F)=C/C(F)(F)F)c2ccccc12 CHEMBL4111702 IC50 90.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)c4cc5cc(F)ccc5[nH]4)C[C@@H]3C)nc2c(F)c1OC CHEMBL3900170 IC50 90.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccco4)CC3)nc2c(F)c1OC CHEMBL4112164 IC50 90.0 nM
COc1cc2c(N)nc(N3CCN(C(=O)C[C@@H](N)c4ccc(Cl)cc4)CC3)nc2c(F)c1OC CHEMBL4112845 IC50 90.0 nM
CC[C@H]1CN(C(=O)C[C@@H](N)c2ccc(C(F)(F)F)cc2)CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1 CHEMBL3956046 IC50 90.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NC[C@@H]2CC2(Cl)Cl)c2ccccc12 CHEMBL4108775 IC50 90.0 nM
COC(=O)c1ccc2c(C(N)=O)nn(CC(=O)N(CC(=O)NCc3cccc(Cl)c3F)C3CC3)c2c1 CHEMBL5219765 IC50 90.0 nM
COC(=O)c1cccc2c(C(C)=O)cn(CC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NCc3cccc(Cl)c3F)c12 CHEMBL3678759 IC50 91.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2nnccc12 CHEMBL3678868 IC50 91.0 nM
NC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cncc(Br)c2)c2ccccc21 CHEMBL3668701 IC50 93.0 nM
C[C@@]12C[C@@H](C(=O)Nc3cccc(OC(F)(F)F)c3F)N(C(=O)Cn3nc(C(N)=O)c4ccncc43)[C@@H]1C2 CHEMBL3683714 IC50 93.0 nM
COC1CCN(c2cc(Cl)c(F)c(CNC(=O)[C@@H]3C[C@@H](F)CN3C(=O)Nc3cn(C(N)=O)c4ccccc34)c2)CC1 CHEMBL3663983 IC50 94.0 nM
NC(=O)n1cc(NC(=O)N2CC(F)(F)C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc21 CHEMBL3673733 IC50 95.0 nM
NC(=O)n1cc(NC(=O)N2CCS[C@H]2C(=O)Nc2cc(Br)cc(C(=O)O)c2)c2ccccc21 CHEMBL3673772 IC50 95.0 nM
NC(=O)n1cc(NC(=O)N2CCC[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2)c2cc(O)ccc21 CHEMBL3673801 IC50 95.0 nM
NC(=O)n1cc(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccc(CCO)cc21 CHEMBL3673900 IC50 95.0 nM
CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(OC(F)(F)F)c2F)c2ccccc12 CHEMBL3678732 IC50 95.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3CC3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(CC(=O)O)ccc12 CHEMBL3678813 IC50 95.0 nM
CC(=O)c1cn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(Br)n2)c2nnccc12 CHEMBL3683728 IC50 95.0 nM
N=C(N)c1cc2ccc(OC(=O)c3cccs3)cc2s1 CHEMBL2220483 IC50 96.0 nM
Cc1cccnc1-c1cccc(NC(=O)[C@@H]2C[C@H]3C[C@H]3N2C(=O)Cn2nc(C(N)=O)c3ccncc32)c1F CHEMBL3678900 IC50 98.0 nM
NC(=O)c1nn(CC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)Nc2cccc(-c3c(F)cccc3F)n2)c2cnccc12 CHEMBL3678932 IC50 98.0 nM
CO[C@H]1[C@@H](C(=O)N[C@@H](C)c2cccc(Cl)c2F)N(C(=O)Cn2cc(C(C)=O)c3ccccc32)C[C@@H]1F CHEMBL3678789 IC50 99.0 nM
CC(C)=C(F)CNC(=O)[C@@H]1C[C@@]2(CO)C[C@H]2N1C(=O)Cn1nc(C(N)=O)c2ccccc21 CHEMBL3976156 IC50 99.0 nM