COc1ccc(C)cc1C1(C(=O)NS(=O)(=O)c2cccc3nc(C)ccc23)CC1c1cccc(C(F)F)n1 CHEMBL5178232 EC50 0.4 nM
O=C(O)c1ccc(C2CC(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c3ccc(OC(F)F)cc3O2)cc1 CHEMBL4558190 EC50 0.5 nM
COc1ccc(C)cc1C1(C(=O)NS(=O)(=O)c2cccc3nc(C)ccc23)CC1c1cccc(C(F)(F)F)c1 CHEMBL5193680 EC50 0.51 nM
CC(C)(C)CC(O)C(=O)Nc1sc2c(c1C(N)=O)CC(C)(C)OC2(C)C CHEMBL4084934 EC50 0.54 nM
COc1ccc(C2CC2(C(=O)NS(=O)(=O)c2cccc3nc(C)ccc23)c2cc(C)ccc2OC)cc1 CHEMBL5178488 EC50 0.66 nM
COc1ccc(C)cc1C1(C(=O)NS(=O)(=O)c2cccc3nc(C)ccc23)CC1c1ccc(C)cc1 CHEMBL5202275 EC50 0.8 nM
COc1cccc(C2CC2(C(=O)NS(=O)(=O)c2cccc3nc(C)ccc23)c2cc(C)ccc2OC)c1 CHEMBL5186971 EC50 0.84 nM
COc1ccc(C)cc1C1(C(=O)NS(=O)(=O)c2cccc3nc(C)ccc23)CC1c1cccc(OC(C)C)n1 CHEMBL5171054 EC50 0.9 nM
Nc1cc(S(=O)(=O)c2ccc(F)cc2)cnc1C(=O)N1CC(O)(C(F)(F)F)C1 CHEMBL4799994 EC50 1.1 nM
CCCCc1c(-c2ccc(O)cc2)[nH]c2nccnc12 CHEMBL75680 Activity 1.5 nM
CC(C)(C)c1cc(F)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O CHEMBL3357142 EC50 2.0 nM
Cc1cn[nH]c1C(=O)Nc1sc2c(c1C(N)=O)CC(C)(C)OC2(C)C CHEMBL4087529 EC50 2.0 nM
CC1(C)Cc2c(sc(NC(=O)c3[nH]ncc3Cl)c2C(N)=O)C(C)(C)O1 CHEMBL4066158 EC50 2.0 nM
O=C(c1c[nH]c2ccccc2c1=O)N(Cc1ccccc1)Cc1ccccc1 CHEMBL3354672 EC50 2.1 nM
CC1(C)Cc2c(sc(NC(=O)[C@@H](O)C(C)(C)C)c2C(N)=O)C(C)(C)O1 CHEMBL4102980 EC50 2.7 nM
Nc1cc(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)cnc1C(=O)NCC1(O)CC1 CHEMBL4787310 EC50 2.8 nM
CC(C)(C)c1cc(C(C)(C)C)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O CHEMBL2010601 EC50 3.0 nM
CC(C)(C)c1cc(C(F)(F)F)c(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O CHEMBL3357143 EC50 3.0 nM
CC(C)(C)c1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1O CHEMBL3357141 EC50 3.0 nM
CC1(C)Cc2c(sc(NC(=O)c3cc(C(F)(F)F)n[nH]3)c2C(N)=O)C(C)(C)O1 CHEMBL4103906 EC50 3.0 nM
CC1(C)Cc2c(sc(NC(=O)c3ccn[nH]3)c2C(N)=O)C(C)(C)O1 CHEMBL4075348 EC50 3.0 nM
Nc1cc(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)cnc1C(=O)NC[C@@H](O)C(F)(F)F CHEMBL4798183 EC50 3.4 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2ccc(OC)c(OC(C)C)c2)cc1 CHEMBL191928 EC50 3.5 nM
Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)[C@H](c1ccc(Br)o1)Oc1ccc(C(=O)O)cc1-3 CHEMBL2386374 IC50 4.0 nM
CC1(C)Cc2c(sc(NC(=O)c3ccccc3O)c2C(N)=O)C(C)(C)O1 CHEMBL4059736 EC50 4.0 nM
CC1Cc2c(sc(NC(=O)c3ccccc3O)c2C(N)=O)C(C)O1 CHEMBL4104967 EC50 4.0 nM
Cc1nc2cccc[n+]2c(C)c1[O-] CHEMBL1779949 IC50 5.0 nM
O=C(O)c1ccc([C@H]2C[C@@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c3ccc(OC(F)F)cc3O2)cc1 CHEMBL4101487 EC50 5.0 nM
Nc1cc(S(=O)(=O)N2CCC(OC(F)(F)F)CC2)cnc1C(=O)NCC(O)C(F)(F)F CHEMBL4781857 EC50 5.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cc(OC(C)C)ccn2)cc1 CHEMBL192547 EC50 6.0 nM
COc1ccc(-c2ccnc3cc(C(=O)Nc4ccc(OCCN5CCOCC5)cc4)nn23)cc1OC CHEMBL5427532 EC50 6.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(OC(C)C)c2)cc1 CHEMBL366586 EC50 6.3 nM
COc1ccc(-c2ccnc3cc(C(=O)Nc4ccc(N5CCOCC5)cc4)nn23)cc1OC CHEMBL5437155 EC50 7.0 nM
Nc1cc(S(=O)(=O)c2ccc(F)cc2)cnc1C(=O)NC[C@@H](O)C(F)(F)F CHEMBL4795705 EC50 7.8 nM
Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(Br)o1)Oc1ccc(C(=O)O)cc1-3 CHEMBL1831075 IC50 8.0 nM
CCc1nc(C(=O)NCC(C)(O)C(F)(F)F)c(N)cc1C(F)(F)F CHEMBL5076312 EC50 8.0 nM
CC(C)(C)c1c[nH]c2cc(NC(=O)c3c[nH]c4ccccc4c3=O)ccc12 CHEMBL3356646 EC50 9.0 nM
O=c1c(-c2cccc([N+](=O)[O-])c2)nc2ccccc2n1Cc1ccccc1 CHEMBL4068723 EC50 9.0 nM
COc1ccc2c(c1)O[C@@H](c1ccc(C(=O)O)cc1)C[C@H]2NC(=O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1 CHEMBL4066196 EC50 9.0 nM
Nc1cc(C(F)(F)F)c(Br)nc1C(=O)NC[C@@H](O)C(F)(F)F CHEMBL5087757 EC50 9.0 nM
C[C@](O)(CNC(=O)c1nc(C(F)(F)F)c(C(F)(F)F)cc1N)C(F)(F)F CHEMBL5088607 EC50 9.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cc(OC3CCCCC3)ccn2)cc1 CHEMBL195630 EC50 9.4 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(OCC(C)C)c2)cc1 CHEMBL191926 EC50 10.0 nM
O=c1c(-c2cccc([N+](=O)[O-])c2)nc2ccccc2n1Cc1cccs1 CHEMBL4071923 EC50 10.0 nM
Nc1cc(C(F)(F)F)c(Br)nc1C(=O)NCC(O)(C(F)(F)F)C(F)(F)F CHEMBL5075860 EC50 10.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2ccnc(OC(C)C)c2)cc1 CHEMBL191243 EC50 11.0 nM
CC(C)(C)c1cc2cc[nH]c2cc1NC(=O)c1c[nH]c2ccccc2c1=O CHEMBL3357126 EC50 11.0 nM
Cc1n[nH]c(C(=O)Nc2sc3c(c2C(N)=O)CC(C)(C)OC3(C)C)c1Cl CHEMBL4076873 EC50 11.0 nM
C[C@H](O)CNC(=O)c1ncc(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)cc1N CHEMBL4785210 EC50 11.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2ccc(OC)c(Oc3ccccc3)c2)cc1 CHEMBL192086 EC50 12.0 nM
Cc1cc(C(=O)Nc2sc3c(c2C(N)=O)CC(C)(C)OC3(C)C)[nH]n1 CHEMBL4079652 EC50 13.0 nM
CC1(C)Cc2c(sc(NC(=O)c3ccccc3O)c2C(N)=O)CO1 CHEMBL4087115 EC50 13.0 nM
NC(=O)c1cc(S(=O)(=O)N2CCCCC2)sc1NC(=O)c1ccn[nH]1 CHEMBL4795314 EC50 13.0 nM
COC(=O)c1ccc(NC(=O)c2cc3nccc(-c4ccc(OC)c(OC)c4)n3n2)cc1 CHEMBL5419096 EC50 14.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(OC3CCCC3)c2)cc1 CHEMBL192583 EC50 15.0 nM
C[C@]1(C(=O)O)N=C2c3ccccc3C=CN2[C@](C)(O)[C@@H]1O CHEMBL1779953 IC50 15.0 nM
C[C@]1(C(=O)O)N=C2c3ccccc3C=CN2[C@](C)(O)[C@H]1O CHEMBL1779954 IC50 15.0 nM
CC1(C)Cc2c(sc(NC(=O)C3(CO)CC3)c2C(N)=O)C(C)(C)O1 CHEMBL4083374 EC50 15.0 nM
C[C@](O)(CNC(=O)c1nc(Br)c(C(F)(F)F)cc1N)C(F)(F)F CHEMBL5084140 EC50 15.0 nM
CCOc1nc(C(=O)NC[C@](C)(O)C(F)(F)F)c(N)cc1C(F)(F)F CHEMBL5075769 EC50 15.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cncc(OC(C)C)c2)cc1 CHEMBL439856 EC50 16.0 nM
Cc1nc2c3ccccc3cc[n+]2c(C)c1[O-] CHEMBL1779950 IC50 16.0 nM
CC1(C)Cc2c(sc(NC(=O)C(C)(C)O)c2C(N)=O)C(C)(C)O1 CHEMBL4101361 EC50 16.0 nM
CCCOc1ccc(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)cc1 CHEMBL4762900 EC50 17.0 nM
Cc1ccc(F)c2[nH]c3c(c12)CN(C(=O)c1cc(C(F)(F)F)[nH]n1)[C@H](C)C3 CHEMBL4741301 EC50 17.0 nM
CN(Cc1ccccc1)S(=O)(=O)c1cc(C(N)=O)c(NC(=O)c2ccn[nH]2)s1 CHEMBL4790007 EC50 17.0 nM
COC(=O)c1ccc(NC(=O)c2cc3nccc(-c4ccc(OC)c(OC)c4)n3n2)c(F)c1 CHEMBL5402877 EC50 17.0 nM
COc1ccc(-c2ccnc3cc(C(=O)Nc4ccc(C(=O)N5CCN(C(=O)OC(C)(C)C)CC5)cc4)nn23)cc1OC CHEMBL5413271 EC50 17.0 nM
O=c1c(-c2ccc3nonc3c2)nc2ccccc2n1Cc1ccccc1 CHEMBL4097026 EC50 18.0 nM
CCOc1ccc(NC(=O)c2cc3nccc(-c4ccc(OC)c(OC)c4)n3n2)cc1 CHEMBL5418678 EC50 18.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(OC3CCCCC3)c2)cc1 CHEMBL373288 EC50 20.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cc(Oc3ccccc3)ccn2)cc1 CHEMBL372893 EC50 20.0 nM
CCc1cc2cc[nH]c2cc1NC(=O)c1c[nH]c2ccccc2c1=O CHEMBL3357125 EC50 20.0 nM
O=c1c(-c2cccc([N+](=O)[O-])c2)nc2ccccc2n1Cc1ccco1 CHEMBL4083281 EC50 20.0 nM
COc1ccc(S(=O)(=O)c2cc(C(N)=O)c(NC(=O)C(C)(C)O)s2)cc1 CHEMBL4781656 EC50 20.0 nM
CN(C)c1nc(C(=O)NCC(C)(O)C(F)(F)F)c(N)cc1C(F)(F)F CHEMBL5082569 EC50 20.0 nM
Cc1ccc(F)c2[nH]c3c(c12)CN(C(=O)c1cc(C(F)(F)F)[nH]n1)C(C)C3 CHEMBL4784101 EC50 22.0 nM
Cc1ccccc1N[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)[C@@H]2CCCCO2)[C@H]1c1ccccc1C(C)C CHEMBL5180031 EC50 22.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 CHEMBL192735 EC50 23.0 nM
CC1(C)Cc2c(sc(NC(=O)C3(O)CC3)c2C(N)=O)C(C)(C)O1 CHEMBL4077923 EC50 23.0 nM
Nc1cc(C(F)(F)F)c(Br)nc1C(=O)NC[C@H](O)C(F)(F)F CHEMBL5081202 EC50 23.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N4CCN(C(=O)c5ccccc5)[C@@H](C)C4)nn23)cc1OC CHEMBL5418645 EC50 23.0 nM
Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(Br)o1)Oc1ccc([N+](=O)[O-])cc1-3 CHEMBL1831069 IC50 25.0 nM
Cc1ccc(C2Oc3ccc([N+](=O)[O-])cc3-n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c32)o1 CHEMBL1831070 IC50 25.0 nM
CCOC(=O)c1ccc2c(c1)-n1c(-c3ccccc3)c3c(=O)n(C)c(=O)n(C)c3c1C(c1ccc(Br)o1)O2 CHEMBL1831073 IC50 25.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(OCC)c2)cc1 CHEMBL195793 EC50 26.0 nM
CC(C)(O)C(=O)Nc1sc(S(=O)(=O)c2ccc(F)cc2)cc1C(N)=O CHEMBL4782437 EC50 26.0 nM
COc1ccc2c(c1)O[C@@H](c1ccc(OC)c(OC)c1)C[C@H]2NC(=O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1 CHEMBL4093612 EC50 28.0 nM
NC(=O)c1cc(S(=O)(=O)c2ccc(F)cc2)sc1NC(=O)c1ccn[nH]1 CHEMBL4784536 EC50 29.0 nM
CCN(CC)c1nc(Nc2ccc3ncsc3c2)nc(OC(C(F)(F)F)C(F)(F)F)n1 CHEMBL4087035 EC50 30.0 nM
Cc1ccc(F)c2[nH]c3c(c12)C(C)N(C(=O)c1cc(C(F)(F)F)[nH]n1)CC3 CHEMBL4743775 EC50 30.0 nM
C[C@@](O)(CNC(=O)c1nc(Br)c(C(F)(F)F)cc1N)C(F)(F)F CHEMBL5088068 EC50 30.0 nM
COc1ccc(-c2ccnc3cc(C(=O)Nc4ccc(C(=O)N5CCOCC5)cc4)nn23)cc1OC CHEMBL5426236 EC50 30.0 nM
CNc1nc(Nc2ccccc2)nc(OCC(F)(F)C(F)F)n1 CHEMBL4079174 EC50 31.0 nM
COC(=O)c1cccc(NC(=O)c2cc3nccc(-c4ccc(OC)c(OC)c4)n3n2)c1 CHEMBL5405578 EC50 31.0 nM
CC(C)(O)CNC(=O)c1ncc(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)cc1N CHEMBL4793801 EC50 33.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cncc(OC3CCCCC3)c2)cc1 CHEMBL372215 EC50 35.0 nM
COc1ncc(C(F)(F)F)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)[C@@H]2CCCCO2)[C@H]1c1ccccc1C(C)C CHEMBL4463048 EC50 35.0 nM
COc1ccc(-c2ccnc3cc(C(=O)Nc4ccc(C(=O)NCCNC(=O)OC(C)(C)C)cc4)nn23)cc1OC CHEMBL5405508 EC50 38.0 nM
CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc2n1CC[N+](C)(C)C CHEMBL3897147 EC50 38.1 nM
COc1nc(C(=O)NC[C@](C)(O)C(F)(F)F)c(N)cc1C(F)(F)F CHEMBL4650318 EC50 39.0 nM
CS(=O)(=O)NC(=O)c1cc(N2CCC(N3CCOCC3)CC2)c2c(C3CCC3)nn(-c3ccccc3)c2n1 CHEMBL5396697 EC50 39.0 nM
COc1ccc(C2(C(=O)Nc3ccc4c(c3)cc(C(C)(C)C)n4C[C@@H](O)CO)CC2(C)C)cc1 CHEMBL3948182 EC50 39.05 nM
Nc1cc(C(F)(F)F)c(Br)nc1C(=O)NCCC(F)(F)F CHEMBL5093146 EC50 40.0 nM
O=C(Nc1cccnc1)[C@H]1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1 CHEMBL370291 EC50 41.0 nM
COc1ncc(C2CCC2)cc1CN[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)[C@@H]2CCCCO2)[C@H]1Cc1cc(C2CCC2)cnc1OC CHEMBL5203914 EC50 41.0 nM
COc1ccc(-c2ccnc3cc(C(=O)Nc4ccc(C(=O)O)cc4F)nn23)cc1OC CHEMBL5432480 EC50 42.0 nM
CS(=O)(=O)NC(=O)c1cc(N2CCC(N3CCOCC3)CC2)c2c(C3CCC3)nn(-c3ccc(F)cc3)c2n1 CHEMBL5431766 EC50 46.0 nM
COC1CCN(c2cc(C(=O)NS(=O)(=O)N(C)C)nc3c2c(C2CCC2)nn3-c2ccc(F)cc2)CC1 CHEMBL5421982 EC50 47.0 nM
CCc1ccccc1[C@H]1[C@@H](OCc2cc(C(F)(F)F)cnc2OC)[C@H](C(C)(C)C)[C@@H](C(=O)O)N1C(=O)[C@@H]1CCCCO1 CHEMBL4461428 EC50 48.0 nM
Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(Br)o1)Nc1ccccc1-3 CHEMBL1831058 IC50 50.0 nM
Cc1ccc(F)c2[nH]c3c(c12)[C@@H](C)N(C(=O)c1cc(C(F)(F)F)[nH]n1)CC3 CHEMBL4752731 EC50 50.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(Cl)c2)cc1 CHEMBL363368 EC50 51.0 nM
O=c1c(-c2cccc([N+](=O)[O-])c2)nc2ccccc2n1Cc1ccccn1 CHEMBL4101279 EC50 52.0 nM
COc1ncc(C(F)(F)F)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)[C@@H]2CCCCO2)[C@H]1c1ccccc1CC(C)C CHEMBL4570987 EC50 52.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cn1 CHEMBL372489 EC50 53.0 nM
C=CCn1c(=O)c(-c2cccc([N+](=O)[O-])c2)nc2ccccc21 CHEMBL4098817 EC50 55.0 nM
Cc1ccc(F)c2[nH]c3c(c12)CN(C(=O)c1cc(C(F)(F)F)[nH]n1)CC3 CHEMBL4745695 EC50 60.0 nM
CS(=O)(=O)NC(=O)c1cc(N2CCC(C#N)CC2)c2c(C3CCC3)nn(-c3ccccc3)c2n1 CHEMBL5435759 EC50 60.0 nM
CCCCCc1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 CHEMBL195690 EC50 61.0 nM
CN(C)S(=O)(=O)NC(=O)c1cc(N2CCC(N3CCOCC3)CC2)c2c(C3CCC3)nn(-c3ccc(F)cc3)c2n1 CHEMBL5424437 EC50 62.0 nM
O=c1c(-c2cccc([N+](=O)[O-])c2)nc2cc(Br)ccc2n1Cc1ccccc1 CHEMBL4064125 EC50 63.0 nM
CCn1c(=O)c(-c2cccc([N+](=O)[O-])c2)nc2ccccc21 CHEMBL4060418 EC50 65.0 nM
COc1ccc(-c2ccnc3cc(C(=O)Nc4ccccc4)nn23)cc1OC CHEMBL5440649 EC50 65.0 nM
CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)c(F)cc2n1C[C@@H](O)CO CHEMBL3923765 EC50 65.95 nM
CCCCN(C(C)=O)c1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 CHEMBL195438 EC50 66.0 nM
O=C(Nc1ccc(Cl)nc1)[C@H]1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1 CHEMBL366200 EC50 66.0 nM
COc1ncc(C(F)(F)F)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)[C@@H]2CCCCO2)[C@H]1c1ccccc1C1CC1 CHEMBL4475985 EC50 66.0 nM
O=c1c(-c2cccc([N+](=O)[O-])c2)nc2cc(Cl)ccc2n1Cc1ccccc1 CHEMBL4083185 EC50 70.0 nM
O=C(c1ccc(-c2ccccc2)cc1)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccccc1 CHEMBL4763661 EC50 70.0 nM
CC(O)CNC(=O)c1nc(Br)c(C(F)(F)F)cc1N CHEMBL5082261 EC50 70.0 nM
CC(C)c1ccc(NC(=O)[C@H](c2ccccc2)N(C)C(=O)Cc2c[nH]c3ccccc23)cc1 CHEMBL5429576 EC50 70.0 nM
CNc1nc(Nc2ccc([N+](=O)[O-])cc2)nc(OCC(F)(F)C(F)F)n1 CHEMBL4089490 EC50 70.0 nM
CCCCCN(C(C)=O)c1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 CHEMBL365601 EC50 71.0 nM
COC1CCN(c2cc(C(=O)NS(C)(=O)=O)nc3c2c(C2CCC2)nn3-c2ccccc2)CC1 CHEMBL5402996 EC50 72.0 nM
O=C(O)c1cccc([C@H]2C[C@@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c3ccc(OC(F)F)cc3O2)c1 CHEMBL4093771 EC50 75.0 nM
CC1(C)Cc2c(sc(NC(=O)C(C)(C)CO)c2C(N)=O)C(C)(C)O1 CHEMBL4085032 EC50 75.0 nM
CC(C)(O)CNC(=O)c1nc(Br)c(C(F)(F)F)cc1N CHEMBL5071764 EC50 77.0 nM
COC(=O)c1cc(-c2ccco2)c(C(F)(F)F)cc1N CHEMBL5080252 EC50 78.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cc(Cl)ccn2)cc1 CHEMBL189924 EC50 79.0 nM
NC(=O)c1cc(S(=O)(=O)c2ccc(F)cc2)sc1NC(=O)C1(O)CC1 CHEMBL4777140 EC50 79.0 nM
CCOC(=O)c1ccc2c(c1)-n1c(-c3ccccc3)c3c(=O)n(C)c(=O)n(C)c3c1C(c1ccc(C)o1)O2 CHEMBL1831074 IC50 80.0 nM
Cc1ccc(F)c2[nH]c3c(c12)[C@H](C)N(C(=O)c1cc(C(F)(F)F)[nH]n1)CC3 CHEMBL4762302 EC50 80.0 nM
CC(C)(CCO)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc2n1C[C@@H](O)CO CHEMBL3908746 EC50 81.75 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2ccc(Cl)c(Cl)c2)cc1 CHEMBL191797 EC50 82.0 nM
O=C(O)c1cccc([C@H]2C[C@@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c3ccc(C(F)(F)F)cc3O2)c1 CHEMBL4067042 EC50 87.0 nM
O=C(c1ccccc1)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccccc1 CHEMBL4164907 EC50 87.0 nM
Cc1ccc(C2Nc3ccccc3-n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c32)o1 CHEMBL1087004 IC50 90.0 nM
Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(Br)o1)Oc1ccccc1-3 CHEMBL1831064 IC50 90.0 nM
CN(C(=O)Cc1c[nH]c2ccccc12)[C@H](C(=O)Nc1ccc(F)cc1)c1ccccc1 CHEMBL2068831 EC50 90.0 nM
O=C(c1cc(C(F)(F)F)[nH]n1)N1CCc2[nH]c3c(F)cccc3c2C1 CHEMBL4745672 EC50 96.0 nM
CCCCCCc1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 CHEMBL195376 EC50 100.0 nM
Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(I)o1)Nc1ccccc1-3 CHEMBL1831059 IC50 100.0 nM
CC(C)(C)c1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1F CHEMBL3357140 EC50 100.0 nM
CC(C)(C)c1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1 CHEMBL3357139 EC50 100.0 nM
CC(C)(C)c1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1CO CHEMBL3357136 EC50 100.0 nM
CC(C)(C)c1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1N CHEMBL3357132 EC50 100.0 nM
CCc1c[nH]c2cc(NC(=O)c3c[nH]c4ccccc4c3=O)ccc12 CHEMBL3356645 EC50 100.0 nM
O=C(Nc1ccc2cc[nH]c2c1)c1c[nH]c2ccccc2c1=O CHEMBL3354673 EC50 100.0 nM
O=C(O)c1cccc([C@H]2C[C@@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)C[C@@H](c3ccccc3)O2)c1 CHEMBL4483334 EC50 100.0 nM
CSc1ccc(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)cc1 CHEMBL4748761 EC50 100.0 nM
COc1cccc(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)c1 CHEMBL4746430 EC50 100.0 nM
CC1(C)Cc2c(sc(NC(=O)C3CCNC3=O)c2C(N)=O)C(C)(C)O1 CHEMBL4082311 EC50 101.0 nM
COc1ncc(C(F)(F)F)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)[C@@H]2CCCCO2)[C@H]1c1ccccc1C CHEMBL4588847 EC50 105.0 nM
COc1ncc(C(C)(C)C)cc1CN[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL5190632 EC50 107.0 nM
O=c1c(-c2cccc([N+](=O)[O-])c2)nc2c(Cl)cccc2n1Cc1ccccc1 CHEMBL4099611 EC50 110.0 nM
O=C(O)c1cccc([C@H]2C[C@@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c3ccc(F)cc3O2)c1 CHEMBL4077999 EC50 110.0 nM
COc1ccc(OC)c(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)c1 CHEMBL4776895 EC50 110.0 nM
O=C(c1ccc2c(c1)OCO2)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccccc1 CHEMBL4752107 EC50 110.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N4CCN(C(=O)c5ccccc5)CC4)nn23)cc1OC CHEMBL5416041 EC50 110.0 nM
CNc1nc(C(=O)NCC(C)(O)C(F)(F)F)c(N)cc1C(F)(F)F CHEMBL5075105 EC50 111.0 nM
COc1ccc(C(C)(C)C)cc1CN[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL5173841 EC50 113.0 nM
O=C(Nc1ccc(Cl)cc1)[C@@H]1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1 CHEMBL369882 EC50 119.0 nM
CNc1nc(Nc2ccccc2)nc(OC(C(F)(F)F)C(F)(F)F)n1 CHEMBL4097188 EC50 120.0 nM
CN(C)c1ccc2cc(C(=O)N3CCc4[nH]c5ccccc5c4C3)[nH]c2c1 CHEMBL4741626 EC50 120.0 nM
CC1(C)Cc2c(sc(NC(=O)c3cn[nH]c3)c2C(N)=O)C(C)(C)O1 CHEMBL4067101 EC50 125.0 nM
CC1(C)Cc2c(sc(NC(=O)[C@H](O)C(C)(C)C)c2C(N)=O)C(C)(C)O1 CHEMBL4077574 EC50 127.0 nM
O=C(c1cccc(F)c1)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccccc1 CHEMBL4753660 EC50 130.0 nM
COc1cc(F)c2[nH]c3c(c2c1)CN(C(=O)c1cc(C(F)(F)F)[nH]n1)CC3 CHEMBL4750673 EC50 130.0 nM
COc1ccc(-c2ccnc3cc(C(=O)NC4CCCCC4)nn23)cc1OC CHEMBL5405327 EC50 130.0 nM
COc1ncc(C(C)(C)C)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL4553881 EC50 132.0 nM
CC1(C)Cc2c(sc(NC(=O)Cc3ccn[nH]3)c2C(N)=O)C(C)(C)O1 CHEMBL4059537 EC50 136.0 nM
COc1ccc(C23CC4CC(CC(C4)C2)C3)cc1CN[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL5204350 EC50 136.0 nM
COc1ncc(C(F)(F)F)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)OC(C)C)[C@H]1c1ccccc1 CHEMBL4517461 EC50 137.0 nM
Nc1ccc([N+](=O)[O-])cc1-c1nc2ccccc2n(Cc2ccccc2)c1=O CHEMBL4086433 EC50 138.0 nM
COc1ccc(Cl)cc1Nc1nc(-c2sc(NC(=O)C(C)(C)C)nc2C)c(-n2cc(-c3ccccc3)nn2)s1 CHEMBL2069572 EC50 140.0 nM
CCN(CC)c1nc(Nc2cccc(F)c2)nc(OC(C(F)(F)F)C(F)(F)F)n1 CHEMBL4097536 EC50 140.0 nM
COc1ccccc1C(=O)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccccc1 CHEMBL4749432 EC50 140.0 nM
CC(C)c1ccccc1[C@H]1[C@@H](Nc2cccnc2N(C)C)[C@H](C(C)(C)C)[C@@H](C(=O)O)N1C(=O)[C@@H]1CCCCO1 CHEMBL5202497 EC50 142.0 nM
CCCCOc1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 CHEMBL370964 EC50 145.0 nM
CS(=O)(=O)NC(=O)c1cc(-c2ccc(N3CCOCC3)cc2)c2c(C3CCC3)nn(-c3ccccc3)c2n1 CHEMBL5418596 EC50 145.0 nM
CC1(C)Cc2c(sc(NC(=O)c3ccccc3NS(C)(=O)=O)c2C(N)=O)C(C)(C)O1 CHEMBL4066461 EC50 147.0 nM
Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(Cl)o1)Nc1ccccc1-3 CHEMBL1831057 IC50 150.0 nM
Cc1ccc(C2Oc3ccccc3-n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c32)o1 CHEMBL1831066 IC50 150.0 nM
CCN(CC)c1nc(Nc2ccc3ncoc3c2)nc(OC(C(F)(F)F)C(F)(F)F)n1 CHEMBL4104898 EC50 150.0 nM
COc1ncc(C(F)(F)F)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL4533405 EC50 150.0 nM
COc1ccc2[nH]c3c(c2c1)CN(C(=O)c1cc2ccc(N(C)C)cc2[nH]1)CC3 CHEMBL4799939 EC50 150.0 nM
O=C(c1cc(C(F)(F)F)[nH]n1)N1CCc2[nH]c3c(F)cc(F)cc3c2C1 CHEMBL4753956 EC50 150.0 nM
O=C(c1cc(C(F)(F)F)[nH]n1)N1CCc2[nH]c3c(F)ccc(F)c3c2C1 CHEMBL4750010 EC50 150.0 nM
CS(=O)(=O)NC(=O)c1cc(-c2ccc(N3CCC(C#N)CC3)nc2)c2c(C3CCC3)nn(-c3ccccc3)c2n1 CHEMBL5434572 EC50 154.0 nM
COc1ccc(C(C)(C)C)cc1CN[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)[C@@H]2CCCCO2)[C@H]1Cc1cc(C(F)(F)F)cnc1OC CHEMBL5180378 EC50 159.0 nM
CC(C)CCCc1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 CHEMBL364669 EC50 160.0 nM
CCN(CC)c1nc(Nc2cccc(C(=O)O)c2)nc(OC(C(F)(F)F)C(F)(F)F)n1 CHEMBL4080996 EC50 160.0 nM
CCCOc1cccc(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)c1 CHEMBL4742255 EC50 160.0 nM
O=C(c1cc(C(F)(F)F)[nH]n1)N1CCc2[nH]c3ccc(OC(F)(F)F)cc3c2C1 CHEMBL4796353 EC50 160.0 nM
COc1ccc(Oc2cccc(C(=O)N3Cc4ccccc4C[C@@H]3C(=O)Nc3ccc(Cl)cc3)c2)cc1 CHEMBL191191 EC50 167.0 nM
Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(Br)o1)Nc1ccc([N+](=O)[O-])cc1-3 CHEMBL1831071 IC50 170.0 nM
Cc1ccc(C2Oc3cc([N+](=O)[O-])c(Cl)cc3-n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c32)o1 CHEMBL1831072 IC50 170.0 nM
COc1ccc(C(F)(F)F)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL4551092 EC50 173.0 nM
CCCCCc1ccc(NC(=O)[C@@H]2Cc3ccccc3CN2C(=O)c2cccc(OC)c2)cc1 CHEMBL191294 EC50 176.0 nM
CCCn1c(=O)c(-c2cccc([N+](=O)[O-])c2)nc2ccccc21 CHEMBL4071817 EC50 177.0 nM
O=C(c1cccc(Br)c1)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccccc1 CHEMBL4800413 EC50 180.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N[C@H]4CC[C@H](C(=O)OC)CC4)nn23)cc1OC CHEMBL5400075 EC50 180.0 nM
CC(C)(C)c1cc2c(C#N)c(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ccc2n1CCO CHEMBL3898560 EC50 181.0 nM
COc1ncc(C2CCC2)cc1CN[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL5177312 EC50 184.0 nM
COc1ccc(C(C)C)cc1CN[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL5181801 EC50 188.0 nM
CC1(C)Cc2c(sc(NC(=O)c3cccnc3O)c2C(N)=O)C(C)(C)O1 CHEMBL4081673 EC50 190.0 nM
COc1ccc(C23CC4CC42C3)cc1CN[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL5187015 EC50 190.0 nM
COc1ccc(CN2CCc3nc(-c4ccccn4)nc(NCCCn4ccnc4)c3C2)cc1 CHEMBL3746547 pEC50 199.53 nM
CC(=O)NCCCNc1nc(-c2ccccn2)nc2c1CN(Cc1ccc(F)cc1)CC2 CHEMBL4172497 pEC50 199.53 nM
Fc1ccc(CN2CCc3nc(-c4ccccn4)nc(NCCCN4CCCC4)c3C2)cc1 CHEMBL4172914 pEC50 199.53 nM
CN(C)CCN1CCN(c2nc(-c3ccccn3)nc3c2CN(Cc2ccsc2)CC3)CC1 CHEMBL3746133 pEC50 199.53 nM
CC(C)c1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1 CHEMBL3356632 EC50 200.0 nM
CC(C)c1ccccc1NC(=O)c1c[nH]c2ccccc2c1=O CHEMBL3356630 EC50 200.0 nM
CCc1ccccc1NC(=O)c1c[nH]c2ccccc2c1=O CHEMBL3356627 EC50 200.0 nM
Fc1ccc(CN2CCc3nc(-c4ccccn4)nc(NCCN4CCCC4)c3C2)cc1 CHEMBL3747159 EC50 200.0 nM
CC(=O)NCCNc1nc(-c2ccccn2)nc2c1CN(Cc1ccc(F)cc1)CC2 CHEMBL3745927 EC50 200.0 nM
CCN(CC)c1nc(Nc2cccc([N+](=O)[O-])c2)nc(OC(C(F)(F)F)C(F)(F)F)n1 CHEMBL4078552 EC50 200.0 nM
COc1ccc2c(c1)OC(c1ccc(OC)c(OC)c1)CC2NC(=O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1 CHEMBL4101344 EC50 200.0 nM
Cc1ccc2c3c([nH]c2c1)CCN(C(=O)c1cc(C(F)(F)F)[nH]n1)C3 CHEMBL4759920 EC50 200.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N4CCN(C(=O)c5ccccc5)C(C)(C)C4)nn23)cc1OC CHEMBL5432387 EC50 200.0 nM
O=C(Nc1ccc(F)cc1)[C@H]1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1 CHEMBL365755 EC50 202.0 nM
CCCCc1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 CHEMBL427361 EC50 202.0 nM
CS(=O)(=O)NC(=O)c1cc(N2CCCCC2)c2c(C3CCC3)nn(-c3ccccc3)c2n1 CHEMBL5418392 EC50 209.0 nM
COc1ccc2c(c1)[C@H](NC(=O)C1(c3ccc4c(c3)OC(F)(F)O4)CC1)C[C@H](c1cccc(C(=O)O)c1)O2 CHEMBL4096042 EC50 210.0 nM
CCN(CC)c1ccc(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)cc1 CHEMBL4786568 EC50 210.0 nM
COc1ncc(C(F)(F)F)cc1CN[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL5172188 EC50 210.0 nM
COc1ncc(C(F)(F)F)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)[C@@H]2CCCCO2)[C@H]1c1ccccc1 CHEMBL4547279 EC50 213.0 nM
COc1ncc(C(F)(F)F)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)[C@@H]2CCCCO2)[C@H]1c1ccccc1Cl CHEMBL4546985 EC50 222.0 nM
CC1(C)CCn2c1cc1cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc12 CHEMBL3936630 EC50 228.5 nM
CC(O)(CNC(=O)c1ncc(C(F)(F)F)cc1N)C(F)(F)F CHEMBL5079547 EC50 229.0 nM
CCCCCCCc1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 CHEMBL192245 EC50 230.0 nM
COc1ccc2c(c1)O[C@@H](c1cccc(C(=O)O)c1)C[C@H]2NC(=O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1 CHEMBL4085871 EC50 230.0 nM
O=C(c1cc(C(F)(F)F)[nH]n1)N1CCc2[nH]c3ccccc3c2C1 CHEMBL4755366 EC50 230.0 nM
Cc1cc(F)c2[nH]c3c(c2c1)CN(C(=O)c1cc(C(F)(F)F)[nH]n1)CC3 CHEMBL4748780 EC50 230.0 nM
CCN(CC)c1nc(Nc2ccccc2)nc(OC(C(F)(F)F)C(F)(F)F)n1 CHEMBL4100901 EC50 240.0 nM
COC(=O)c1cc(-c2ncco2)c(C(F)(F)F)cc1N CHEMBL5085939 EC50 240.0 nM
Cc1nc(C(=O)NCC(C)(O)C(F)(F)F)c(N)cc1C(F)(F)F CHEMBL5083308 EC50 240.0 nM
COc1ccc(Cl)cc1CN[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL5173199 EC50 241.0 nM
COc1ncc(C2CCCC2)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL4453629 EC50 247.0 nM
O=C(c1cccc(-c2ccccc2)c1)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccccc1 CHEMBL4754263 EC50 250.0 nM
CNC(=O)c1nc(Br)c(C(F)(F)F)cc1N CHEMBL5086285 EC50 250.0 nM
COCCN(C)c1ccc(-c2cc(C(=O)NS(C)(=O)=O)nc3c2c(C2CCC2)nn3-c2ccccc2)cn1 CHEMBL5406344 EC50 251.0 nM
O=C(O)c1ccc([C@H]2C[C@@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)C[C@@H](c3ccccc3)O2)cc1 CHEMBL4571017 EC50 260.0 nM
CC(C)c1ccc(NC(=O)C(c2ccccc2)N(C)C(=O)Cc2c[nH]c3ccccc23)cc1 CHEMBL1949980 EC50 260.0 nM
O=C(Nc1ccc(Cl)cc1)[C@H]1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccn2)c1 CHEMBL364672 EC50 268.0 nM
Cc1ccc2[nH]c3c(c2c1)CN(C(=O)c1cc(C(F)(F)F)[nH]n1)CC3 CHEMBL4757589 EC50 270.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N4CCN(C(=O)OC(C)(C)C)CC4)nn23)cc1OC CHEMBL5394040 EC50 270.0 nM
COCCN(C)c1ccc(-c2cc(C(=O)NS(C)(=O)=O)nc3c2c(C2CCC2)nn3-c2ccccc2)cc1 CHEMBL5434270 EC50 271.0 nM
CC(C)(CO)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc2n1C[C@@H](O)CO CHEMBL3544914 EC50 272.0 nM
C=CCc1cc(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)ccc1O CHEMBL4751995 EC50 280.0 nM
O=C(Nc1ccc(Cl)cc1)[C@H]1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccc(C(F)(F)F)cc2)c1 CHEMBL195850 EC50 282.0 nM
CC(C)(C)c1cc2c(C#N)c(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)ccc2[nH]1 CHEMBL3986594 EC50 283.5 nM
CC(C)(CCOC[C@@H](O)CO)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc2[nH]1 CHEMBL3933231 EC50 285.0 nM
COc1ccc(-c2ccnc3cc(C(=O)Nc4ccc(C(=O)N5CCN(C)CC5)cc4)nn23)cc1OC CHEMBL5428768 EC50 290.0 nM
O=C(Nc1ccc(Cl)cc1)[C@H]1Cc2ccccc2CN1C(=O)c1cccc(Cc2ccccc2)c1 CHEMBL434733 EC50 291.0 nM
O=C(Nc1ccc(Br)cc1)[C@H]1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1 CHEMBL176160 EC50 292.0 nM
O=C(Nc1ccc(Cl)cc1)C1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1 CHEMBL190630 EC50 294.0 nM
COc1ccc(Cl)cc1Nc1nc2c(s1)CCCc1nc(NC(=O)C(C)(C)C)sc1-2 CHEMBL495336 EC50 300.0 nM
O=C(O)c1ccc(/C=C2\SC(=S)N(c3cccc(C(F)(F)F)c3)C2=O)cc1 CHEMBL461939 IC50 300.0 nM
CCc1ccc(C2Nc3ccccc3-n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c32)o1 CHEMBL1831054 IC50 300.0 nM
CC(C)c1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1N CHEMBL3357130 EC50 300.0 nM
CC(C)c1ccc(CN2CCc3nc(-c4ccccn4)nc(N4CCN(CCN(C)C)CC4)c3C2)cc1 CHEMBL3747771 EC50 300.0 nM
CCN(C(C)=O)C1CCN(c2nc(-c3ccccn3)nc3c2CN(Cc2ccc(OC)cc2)CC3)C1 CHEMBL3746126 EC50 300.0 nM
CCOC(=O)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccc(Br)cc1 CHEMBL4170137 EC50 300.0 nM
COc1ccc(-c2ccnc3cc(C(=O)Nc4ccc(C(=O)O)cc4)nn23)cc1OC CHEMBL5429999 EC50 310.0 nM
COC(=O)C12CC(NC(=O)c3cc4nccc(-c5ccc(OC)c(OC)c5)n4n3)(C1)C2 CHEMBL5421603 EC50 310.0 nM
O=C(Nc1ccc(I)cc1)[C@H]1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1 CHEMBL367321 EC50 314.0 nM
COc1ccc(C(C)(C)C)cc1CN[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)[C@@H]2CCCCO2)[C@H]1c1ccccc1 CHEMBL5178099 EC50 321.0 nM
CC1(c2nn(-c3ccccc3)c3nc(C(=O)O)cc(-c4ccc(N5CCOCC5)cc4)c23)CCC1 CHEMBL5401936 EC50 325.0 nM
NC(=O)c1c(NC(=O)c2ccccc2Cl)sc2c1CCCC2 CHEMBL210832 EC50 326.0 nM
COC(=O)c1cc(-c2cccnc2)c(C(F)(F)F)cc1N CHEMBL5076850 EC50 329.0 nM
O=c1c(-c2cccc(Br)c2)nc2ccccc2n1Cc1ccccc1 CHEMBL4093693 EC50 330.0 nM
Cc1cc(C)cc(/N=C2/NC(=O)/C(=C/c3ccc(O)cc3)S2)c1 CHEMBL5412406 EC50 332.0 nM
O=C(Nc1ccc(Cl)cc1)[C@H]1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1 CHEMBL364514 EC50 336.0 nM
O=C(Nc1ccc(Cl)cc1)[C@H]1Cc2ccccc2CN1C(=O)c1ccccc1Oc1ccccc1 CHEMBL192134 EC50 338.0 nM
COc1ccccc1CC(=O)Nc1nnc(Cc2ccc(OC)c(OC)c2)s1 CHEMBL4637667 EC50 340.0 nM
COc1ncc(C(F)(F)F)cc1CO[C@H]1[C@H](C(C)(C)C)[C@@H](C(=O)O)N(C(=O)[C@H]2CCCCO2)[C@H]1c1ccccc1 CHEMBL4581904 EC50 346.0 nM
Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(C(F)(F)F)o1)Nc1ccccc1-3 CHEMBL1831060 IC50 350.0 nM
COc1ccc2[nH]c3c(c2c1)CN(C(=O)c1cc(C(F)(F)F)[nH]n1)CC3 CHEMBL4744909 EC50 350.0 nM
CC(C)(C)C(=O)Nc1sc(S(=O)(=O)c2ccc(F)cc2)cc1C(N)=O CHEMBL4776744 EC50 352.0 nM
O=C(c1ccc(OC(F)(F)F)cc1)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccccc1 CHEMBL4746792 EC50 360.0 nM
COC(=O)c1cc(I)c(C(F)(F)F)cc1N CHEMBL5083598 EC50 362.0 nM
N#CC1CCN(c2ccc(-c3cc(C(=O)O)nc4c3c(C3CCC3)nn4-c3ccccc3)cn2)CC1 CHEMBL5414290 EC50 365.0 nM
Cc1cccc(-c2c3c(=O)n(C)c(=O)n(C)c3c3n2-c2ccccc2OC3c2ccc(Cl)o2)c1 CHEMBL1831067 IC50 370.0 nM
O=C(c1ccc(N2CCCC2)cc1)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccccc1 CHEMBL4786072 EC50 370.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N4CC[C@@H](NC(=O)OC(C)(C)C)C4)nn23)cc1OC CHEMBL5429343 EC50 370.0 nM
CCOc1ccccc1CC(=O)Nc1nnc(Cc2ccc(OC)c(OC)c2)s1 CHEMBL5407009 EC50 377.0 nM
O=C(c1cccs1)N1N=C(c2ccccc2)CC1c1ccccc1[N+](=O)[O-] CHEMBL5417364 EC50 385.0 nM
O=C(Nc1ccc(Cl)cc1)[C@H]1Cc2ccccc2CN1C(=O)c1cccc(Sc2ccccc2)c1 CHEMBL370945 EC50 394.0 nM
COc1ccc(CN2CCc3nc(-c4ccccn4)nc(N4CCN(CCO)CC4)c3C2)cc1 CHEMBL3746769 pEC50 398.11 nM
CCCc1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1N CHEMBL3357131 EC50 400.0 nM
O=C(Nc1ccc2c(c1)NCC2)c1c[nH]c2ccccc2c1=O CHEMBL3356635 EC50 400.0 nM
OC1CCCN(c2nc(-c3ccccn3)nc3c2CN(Cc2ccccc2)CC3)C1 CHEMBL3745884 EC50 400.0 nM
COc1ccc(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)c(OC)c1 CHEMBL4788444 EC50 400.0 nM
CNc1nc(Nc2cccc([N+](=O)[O-])c2)nc(OCC(F)(F)F)n1 CHEMBL5413245 EC50 400.0 nM
O=C(O)c1cc(-c2ccc(N3CCOCC3)cc2)c2c(C3CCC3)nn(-c3ccccc3)c2n1 CHEMBL5438304 EC50 406.0 nM
CCOC(=O)c1ccc(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)cc1 CHEMBL4754741 EC50 410.0 nM
COc1ccc(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)cc1Cl CHEMBL4793532 EC50 410.0 nM
CCOc1ccc(NC(=O)[C@H]2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 CHEMBL425191 EC50 420.0 nM
CCCCCc1ccc(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)cc1 CHEMBL4796687 EC50 430.0 nM
O=C(c1cc(C(F)(F)F)[nH]n1)N1CCc2[nH]c3ccc(C(F)(F)F)cc3c2C1 CHEMBL4795877 EC50 440.0 nM
CC(C)c1nn(-c2ccccc2)c2nc(C(=O)O)cc(-c3ccc(N4CCOCC4)cc3)c12 CHEMBL5401033 EC50 448.0 nM
COCCN(C)c1ccc(-c2cc(C(=O)O)nc3c2c(C2CCC2)nn3-c2ccccc2)cc1 CHEMBL5404658 EC50 448.0 nM
COc1ccc2c(c1)OC(c1ccccc1)CC2NC(=O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1 CHEMBL4074654 EC50 450.0 nM
COc1ccc(C(=O)c2sc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)nc2-c2ccccc2)cc1 CHEMBL4759522 EC50 450.0 nM
COC(=O)c1cc(C2CCCO2)c(C(F)(F)F)cc1N CHEMBL5091133 EC50 462.0 nM
CCS(=O)(=O)NC(=O)c1cc(-c2ccc(N3CCOCC3)cc2)c2c(C)nn(-c3ccccc3)c2n1 CHEMBL5394166 EC50 465.0 nM
CC1(C)Cc2c(sc(NC(=O)c3nnc[nH]3)c2C(N)=O)C(C)(C)O1 CHEMBL4076611 EC50 467.0 nM
COC(=O)c1ccc(CNC(=O)c2cc3nccc(-c4ccc(OC)c(OC)c4)n3n2)cc1 CHEMBL5401740 EC50 470.0 nM
Cc1cccc2[nH]c3c(c12)CN(C(=O)c1cc(C(F)(F)F)[nH]n1)CC3 CHEMBL4741540 EC50 480.0 nM
O=C(c1cc(C(F)(F)F)[nH]n1)N1CCc2[nH]c3ccc(F)cc3c2C1 CHEMBL4780584 EC50 480.0 nM
COCCN(C)c1ccc(-c2cc(C(=O)O)nc3c2c(C2CCC2)nn3-c2ccccc2)cn1 CHEMBL5395827 EC50 483.0 nM
Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(I)o1)Oc1ccccc1-3 CHEMBL1831065 IC50 500.0 nM
CCN(CC)c1nc(Nc2cccc(C(=O)O)c2)nc(OCC(F)(F)C(F)F)n1 CHEMBL4096577 EC50 500.0 nM
CC(C)(C)c1nn(-c2ccccc2)c2nc(C(=O)O)cc(-c3ccc(N4CCOCC4)cc3)c12 CHEMBL5399205 EC50 517.0 nM
O=C(c1ccc(Br)cc1)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccccc1 CHEMBL4751090 EC50 530.0 nM
Cc1ccc(F)c2[nH]c3c(c12)[C@@H]1CC[C@H](C3)N1C(=O)c1cc(C(F)(F)F)[nH]n1 CHEMBL4799465 EC50 540.0 nM
CCOC(=O)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1cccc(Cl)c1 CHEMBL4159515 pEC50 549.54 nM
COC(=O)c1ccc(N)c(-c2nc3ccccc3n(Cc3ccccc3)c2=O)c1 CHEMBL4084994 EC50 550.0 nM
O=C(c1cc(C(F)(F)F)[nH]n1)N1CCc2[nH]c3c(F)cc(C(F)(F)F)cc3c2C1 CHEMBL4799047 EC50 570.0 nM
COc1ccc(Cc2nnc(NC(=O)Cc3c(F)cccc3Cl)s2)cc1OC CHEMBL5425079 EC50 571.0 nM
O=C(Nc1ccc(Cl)cc1)[C@H]1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccc(F)cc2)c1 CHEMBL195151 EC50 590.0 nM
COc1ccc(Cl)cc1Nc1nc(-c2nnc(NC(=O)C(C)(C)C)o2)cs1 CHEMBL3358694 EC50 590.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N[C@H]4CC[C@@H](C(=O)OC)CC4)nn23)cc1OC CHEMBL5403993 EC50 590.0 nM
Cc1cccc(-c2c3c(=O)n(C)c(=O)n(C)c3c3n2-c2ccccc2OC3c2ccc(C)o2)c1 CHEMBL1831068 IC50 600.0 nM
COc1ccc2[nH]c3c(c2c1)CCNC31CCN(Cc2cc(F)c(F)cc2F)CC1 CHEMBL4752473 EC50 600.0 nM
CCc1ccc(NS(=O)(=O)c2cn(Cc3ccccn3)c3ncccc23)cc1 CHEMBL5288577 EC50 600.0 nM
Cc1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)s1 CHEMBL4078274 EC50 652.0 nM
COc1ccc(Cl)cc1Nc1nnc(-c2csc(NC(=O)C(C)(C)C)n2)o1 CHEMBL3358692 EC50 660.0 nM
COc1ccc(Cc2nnc(NC(=O)Cc3cccs3)s2)cc1OC CHEMBL1449253 EC50 685.0 nM
O=c1c(-c2ccc(F)c([N+](=O)[O-])c2)nc2ccccc2n1Cc1ccccc1 CHEMBL4101412 EC50 690.0 nM
COc1ccc(Cl)cc1Nc1nc(-c2sc(NC(=O)C(C)(C)C)nc2C)cs1 CHEMBL262627 Kd 700.0 nM
Cc1cccc(-c2c3c(=O)n(C)c(=O)n(C)c3c3n2-c2ccccc2NC3c2ccc(C)o2)c1 CHEMBL1222175 IC50(app) 700.0 nM
CC(=O)NC1CCN(c2nc(-c3ccccn3)nc3c2CN(Cc2ccc(Cl)cc2)CC3)CC1 CHEMBL3745838 EC50 700.0 nM
CCN(CC)c1nc(Nc2ccc(F)cc2)nc(OC(C(F)(F)F)C(F)(F)F)n1 CHEMBL4093184 EC50 700.0 nM
CCc1ccc(NS(=O)(=O)c2cn(Cc3ccccc3C#N)c3ncccc23)cc1 CHEMBL5275959 EC50 700.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N4CC(NC(=O)OC(C)(C)C)C4)nn23)cc1OC CHEMBL5426673 EC50 700.0 nM
Cc1nn(-c2ccccc2)c2nc(C(=O)O)cc(-c3ccc(N(C)C4CCOCC4)cc3)c12 CHEMBL5435043 EC50 705.0 nM
COc1ccc(-c2ccnc3cc(C(=O)NCc4ccc(N5CCOCC5)cc4)nn23)cc1OC CHEMBL5432600 EC50 710.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N4CCN(Cc5ccccc5)CC4)nn23)cc1OC CHEMBL5425596 EC50 730.0 nM
COc1ccc(Cl)cc1Nc1ncc(-c2sc(NC(=O)C(C)(C)C)nc2C)o1 CHEMBL3358691 EC50 740.0 nM
CCCCc1c(O)c2c(Cl)cccc2[n+]2ccccc12 CHEMBL174255 EC50 750.0 nM
Cc1nc(NC(=O)C(C)(C)C)sc1-c1cc(C(=O)NCc2ccccc2)nn1Cc1ccccc1 CHEMBL1097861 EC50 750.0 nM
O=C(NC1C[C@H](c2cccc(CO)c2)Oc2ccccc21)C1(c2ccc3c(c2)OC(F)(F)O3)CC1 CHEMBL4094248 EC50 750.0 nM
Cc1nc(NC(=O)C(C)(C)C)sc1-c1cc(Cc2ccccc2)n(C(=O)NCc2ccccc2)n1 CHEMBL4163314 pEC50 758.58 nM
O=C1/C(=C/c2ccc(-c3nn[nH]n3)cc2)SC(=S)N1c1cccc(C(F)(F)F)c1 CHEMBL461940 IC50 760.0 nM
O=c1c(-c2cccc([N+](=O)[O-])c2)nc2ccc(Cl)cc2n1Cc1ccccc1 CHEMBL4061323 EC50 760.0 nM
Cc1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCOC3)s1 CHEMBL4097262 EC50 778.0 nM
O=C(c1cccnc1)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccccc1 CHEMBL4758104 EC50 790.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N4CCN(C(=O)c5ccccc5)[C@H](C)C4)nn23)cc1OC CHEMBL5417294 EC50 790.0 nM
Cc1nc(NC(=O)c2ccc([N+](=O)[O-])cc2)sc1-c1csc(Nc2ccc(Cl)cc2)n1 CHEMBL258536 Kd 800.0 nM
CCOc1ccccc1Nc1nc(-c2sc(NC(=O)C(C)(C)C)nc2C)cs1 CHEMBL258749 Kd 800.0 nM
Cc1ccc(C2Nc3ccccc3-n3c(-c4ccccc4C)c4c(=O)n(C)c(=O)n(C)c4c32)o1 CHEMBL1222176 IC50(app) 800.0 nM
Cc1ccc(C2Nc3cc(C)c(C)cc3-n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c32)o1 CHEMBL1081471 IC50(app) 800.0 nM
O=C(Nc1ccc2ccccc2c1)c1c[nH]c2ccccc2c1=O CHEMBL3356633 EC50 800.0 nM
CCc1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1 CHEMBL3356631 EC50 800.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N4CCC(NC(=O)OC(C)(C)C)CC4)nn23)cc1OC CHEMBL5405505 EC50 810.0 nM
Cc1nn(-c2ccc(F)cc2)c2nc(C(=O)O)cc(-c3ccc(N4CCOCC4)cc3)c12 CHEMBL5417860 EC50 817.0 nM
CC(=O)Nc1ccc([N+](=O)[O-])cc1-c1nc2cccc3c2n(c1=O)CCO3 CHEMBL4077230 EC50 820.0 nM
COc1ccc2[nH]c3c(c2c1)CN(C(=O)c1cc(-c2ccccc2)[nH]n1)CC3 CHEMBL4796643 EC50 820.0 nM
COC(=O)c1ccccc1NC(=O)c1cc2nccc(-c3ccc(OC)c(OC)c3)n2n1 CHEMBL5414889 EC50 820.0 nM
COc1ccc(-c2ccnc3cc(C(=O)N4CCN(c5ccccc5)CC4)nn23)cc1OC CHEMBL5408696 EC50 840.0 nM
O=C(O)c1cccc([C@H]2C[C@@H](NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)CCO2)c1 CHEMBL4467142 EC50 850.0 nM
NC(=O)c1ccc(-n2cnc3c(N)nc(NCCCc4ccccc4)nc32)cc1 CHEMBL4788315 EC50 870.0 nM
CN(C)CCN1CCN(c2nc(-c3ccccn3)nc3c2CN(CC2CCCCC2)CC3)CC1 CHEMBL3747604 pEC50 891.25 nM
CCOC(=O)c1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccc(Cl)cc1 CHEMBL4173592 pEC50 891.25 nM
Cc1sc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)nc1-c1ccc(F)cc1 CHEMBL4169748 pEC50 891.25 nM
COc1ccc(Cl)cc1Nc1nc(-c2sc(NC(=O)c3ccccc3)nc2C)cs1 CHEMBL260775 Kd 900.0 nM
COc1ccc([N+](=O)[O-])cc1Nc1nc2c(s1)CCCCc1nc(NC(=O)C(C)(C)C)sc1-2 CHEMBL3323418 IC50 900.0 nM
CCN(CC)c1nc(Nc2ccc(C(=O)O)cc2)nc(OC(C(F)(F)F)C(F)(F)F)n1 CHEMBL4092200 EC50 900.0 nM
CCN(CC)c1nc(Nc2ccc3cn[nH]c3c2)nc(OC(C(F)(F)F)C(F)(F)F)n1 CHEMBL4067285 EC50 900.0 nM
C=CCn1nc(C(=O)Nc2ccc(OC)cc2)cc1-c1sc(NC(=O)C(C)(C)C)nc1C CHEMBL1098779 EC50 930.0 nM
C=CCc1cc(-c2sc(NC(=O)C(C)(C)C)nc2C)nn1C(=O)Nc1ccc(OC)cc1 CHEMBL4166758 pEC50 933.25 nM
Cc1nn(-c2cccc(F)c2)c2nc(C(=O)O)cc(-c3ccc(N4CCOCC4)cc3)c12 CHEMBL5396223 EC50 934.0 nM
O=C(NC1CC(c2ccc(Cl)cc2)Oc2ccccc21)C1(c2ccc3c(c2)OC(F)(F)O3)CC1 CHEMBL4102835 EC50 940.0 nM
Cc1ccc(F)c2c3c([nH]c12)CCN(C(=O)c1cc(C(F)(F)F)[nH]n1)C3 CHEMBL4776336 EC50 940.0 nM
CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)CCC5)CC3)ccc2n1C[C@@H](O)CO CHEMBL3956217 EC50 981.0 nM
COc1ccc(NC(=O)c2cc(-c3sc(NC(=O)C(C)(C)C)nc3C)n(Cc3cc(Cl)ccc3OC)n2)cc1 CHEMBL1098499 EC50 1000.0 nM
COc1ccc(Cl)cc1Cn1nc(C(=O)N2CCOCC2)cc1-c1sc(NC(=O)C(C)(C)C)nc1C CHEMBL1096523 EC50 1000.0 nM
Cc1ccc(C2c3c4c(c(-c5ccccc5)n3-c3ccccc3N2C)c(=O)n(C)c(=O)n4C)o1 CHEMBL1831053 IC50 1000.0 nM
O=c1c(-c2ccccc2[N+](=O)[O-])nc2ccccc2n1Cc1ccccc1 CHEMBL4103866 EC50 1000.0 nM
O=c1c(-c2ccc([N+](=O)[O-])cc2)nc2ccccc2n1Cc1ccccc1 CHEMBL4085942 EC50 1000.0 nM
O=c1c(-c2ccc(C(F)(F)F)cc2)nc2ccccc2n1Cc1ccccc1 CHEMBL4066115 EC50 1000.0 nM
N#Cc1cccc(-c2nc3ccccc3n(Cc3ccccc3)c2=O)c1 CHEMBL4069832 EC50 1000.0 nM
COc1ccc2c(c1)O[C@H](c1ccc(OC)c(OC)c1)C[C@@H]2NC(=O)C1(c2ccc3c(c2)OC(F)(F)O3)CC1 CHEMBL4066040 EC50 1000.0 nM
COc1ccc(NC(=O)n2nc(-c3sc(NC(=O)C(C)(C)C)nc3C)cc2Cc2cc(Cl)ccc2OC)cc1 CHEMBL4167860 pEC50 1000.0 nM
COc1ccc(Cl)cc1Cc1cc(-c2sc(NC(=O)C(C)(C)C)nc2C)nn1C(=O)N1CCOCC1 CHEMBL4159943 pEC50 1000.0 nM
COc1ncc(C(C)C)cc1CN[C@H]1[C@H](C(C)(C)OC)[C@@H](C(=O)O)N(C(=O)C2CCCCC2)[C@H]1c1ccccc1 CHEMBL4169655 EC50 1000.0 nM
COc1ccc(Cl)cc1Cn1nc(-c2sc(NC(=O)C(C)(C)C)nc2C)cc1C(=O)N1CCOCC1 CHEMBL4450801 EC50 1000.0 nM
CCCCCn1cc(S(=O)(=O)Nc2ccc(CC)cc2)c2cccnc21 CHEMBL5270290 EC50 1000.0 nM