COc1c(O)cc2oc3cc(O)c(CC=C(C)C)c(O)c3c(=O)c2c1CC=C(C)C CHEMBL323197 IC50 4.0 nM
Nc1ccc(-c2cc(Cl)c(Cl)c3[nH]c4c(c23)CN(C(=O)CO)CC4)cn1 CHEMBL4448176 IC50 10.0 nM
Cn1ccc(-c2cc(Cl)c(Cl)c3[nH]c4c(c23)CN(C(=O)CO)CC4)n1 CHEMBL5082056 IC50 14.0 nM
Cn1cc(-c2cc(Cl)c(Cl)c3[nH]c4c(c23)CN(C(=O)CO)CC4)cn1 CHEMBL5174318 IC50 14.0 nM
O=C(CO)N1CCc2[nH]c3c(Cl)c(Cl)cc(-c4cn[nH]c4)c3c2C1 CHEMBL5081956 IC50 27.0 nM
O=C1N=C(N2CCCCC2)S/C1=C1/C(=O)Nc2ccccc21 CHEMBL5203275 IC50 30.0 nM
O=C(NCCCNc1nc(Nc2cccc(NC(=O)N3CCCC3)c2)ncc1I)c1cccs1 CHEMBL577784 IC50 60.0 nM
O=C(COc1ccc(Cl)c2ccccc12)Nc1ncccc1O CHEMBL5206813 IC50 70.0 nM
O=C(Nc1cc(-c2ccccc2)ccn1)c1[nH]ncc1[N+](=O)[O-] CHEMBL5207488 IC50 100.0 nM
Cc1nn(-c2nc3ccc(Cl)c(Cl)c3[nH]2)c(O)c1C1OC(=O)c2ccccc21 CHEMBL4567157 IC50 110.0 nM
O=C(N[C@H]1CCCC[C@H]1C(=O)O)c1cnn2c(O)cc(-c3ccccc3)nc12 CHEMBL4096573 Kd 200.0 nM
O=C(N[C@@H]1CCCC[C@@H]1C(=O)O)C1C=NN2C(O)=CC(c3ccccc3)=NC12 CHEMBL5203753 Kd 200.0 nM
COC(=O)c1nc(N)nc(Nc2cc(F)c(I)c(F)c2)n1 CHEMBL5076595 IC50 240.0 nM
COc1cc2c(-n3ccnc3)ccnc2cc1Cl CHEMBL5206893 IC50 391.0 nM
O=C1NC(=O)/C(=C/c2ccncc2)N1 CHEMBL1288476 IC50 500.0 nM
C#CCOc1cc(/C=C2\SC(=O)N(C)C2=O)c(Br)cc1O CHEMBL4483323 IC50 500.0 nM
CCN1C(=O)S/C(=C\c2cc(OC)c(O)cc2Br)C1=O CHEMBL4474744 IC50 500.0 nM
COc1cc(/C=C2\Sc3ccccc3C2=O)c(Br)cc1O CHEMBL4553894 IC50 500.0 nM
COc1cc(/C=C2\Sc3ncncc3C2=O)c(Br)cc1O CHEMBL4573520 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3ccncc3)c(O)cc2Br)C1=O CHEMBL4528559 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3ccc(NC(=O)c4cccnc4)nc3)c(O)cc2Br)C1=O CHEMBL4464411 IC50 500.0 nM
CCc1cc(/C=C2\SC(=O)N(C)C2=O)c(Br)cc1O CHEMBL4454116 IC50 500.0 nM
COc1cc(/C=C2\SC(=O)N(C)C2=O)c(Br)cc1NS(=O)(=O)C(F)(F)F CHEMBL4535668 IC50 500.0 nM
COc1cc(/C=C2\SC(=O)N(C)C2=O)c(Br)cc1NS(=O)(=O)c1csc(N)n1 CHEMBL4469497 IC50 500.0 nM
CC(=O)Nc1nc(S(=O)(=O)Nc2cc(Br)c(/C=C3\SC(=O)N(C)C3=O)cc2OCc2ccccc2)cs1 CHEMBL4542131 IC50 500.0 nM
COc1cc(/C=C2\SC(=O)N(C)C2=O)c(C)cc1O CHEMBL4473195 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc3cc[nH]c3cc2Br)C1=O CHEMBL4445298 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3cccc4[nH]ccc34)c(O)cc2Br)C1=O CHEMBL4542752 IC50 500.0 nM
CSc1cc(/C=C2\SC(=O)N(C)C2=O)c(Br)cc1O CHEMBL4562036 IC50 500.0 nM
O=C1/C(=C/c2cc(OC(F)(F)F)c(O)cc2Br)Sc2ncccc21 CHEMBL4436575 IC50 500.0 nM
COc1cc(/C=C2\Sc3ncccc3C2=O)c(C)cc1O CHEMBL4453365 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3cnc(C4CCNCC4)nc3)c(O)cc2Br)C1=O CHEMBL4450901 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3cnc(-c4ccccn4)nc3)c(O)cc2Br)C1=O CHEMBL4556780 IC50 500.0 nM
CC(Oc1cc(/C=C2\SC(=O)N(C)C2=O)c(Br)cc1O)c1cncnc1 CHEMBL4436372 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3cnc(N)nc3C3CC3)c(O)c(F)c2Br)C1=O CHEMBL4465235 IC50 500.0 nM
CC(Oc1cc(/C=C2\Sc3ncccc3C2=O)c(Br)cc1O)c1cccnc1 CHEMBL4545148 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3ccc(=O)[nH]c3)c(O)cc2Br)C1=O CHEMBL4448312 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCC3CCN(C(=O)c4cccnc4)CC3)c(O)cc2Br)C1=O CHEMBL4568085 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3ccnc(N)c3)c(O)cc2Br)C1=O CHEMBL4442425 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3cc[nH]c(=O)c3)c(O)cc2Br)C1=O CHEMBL4540899 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3ccnc(N)n3)c(O)cc2Br)C1=O CHEMBL4529256 IC50 500.0 nM
COc1ncc(COc2cc(/C=C3\SC(=O)N(C)C3=O)c(Br)cc2O)cn1 CHEMBL4553066 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3cnc(NC4CC4)nc3)c(O)cc2Br)C1=O CHEMBL4455369 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3cnc(Nc4cccnc4)nc3)c(O)cc2Br)C1=O CHEMBL4452381 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3cnc(-n4ccnc4)nc3)c(O)cc2Br)C1=O CHEMBL4460002 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3cnc(-n4cccn4)nc3)c(O)cc2Br)C1=O CHEMBL4473750 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCCc3ccncc3)c(O)cc2Br)C1=O CHEMBL4555167 IC50 500.0 nM
CC(Oc1cc(/C=C2\SC(=O)N(C)C2=O)c(Br)cc1O)c1cnc(NCCO)nc1 CHEMBL4538887 IC50 500.0 nM
COCCNc1ncc(C(C)Oc2cc(/C=C3\SC(=O)N(C)C3=O)c(Br)cc2O)cn1 CHEMBL4528469 IC50 500.0 nM
Cc1ncc(COc2cc(/C=C3\SC(=O)N(C)C3=O)c(Br)c(F)c2O)cn1 CHEMBL4441672 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3cnc(NCc4cccnc4)nc3)c(O)c(F)c2Br)C1=O CHEMBL4517045 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCc3cnc(N)nc3)c(Oc3cnc(N)s3)cc2Br)C1=O CHEMBL4537996 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(Oc3ccc(=O)[nH]c3)c(O)cc2Br)C1=O CHEMBL4519002 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCC(=O)c3cnc(N)nc3)c(O)c(F)c2Br)C1=O CHEMBL4592540 IC50 500.0 nM
Nc1ncc(COc2cc(/C=c3\sc4nccn4c3=O)c(Br)cc2O)cn1 CHEMBL4458779 IC50 500.0 nM
CC(Oc1cc(/C=c2\sc3nccn3c2=O)c(Br)c(F)c1O)c1cnc(N)nc1 CHEMBL4542967 IC50 500.0 nM
C[S+]([O-])c1ncc(COc2cc(/C=C3\Sc4ncccc4C3=O)c(Br)c(F)c2O)cn1 CHEMBL4588353 IC50 500.0 nM
CC(Oc1cc(/C=C2\SC(=O)N(C)C2=O)c(Br)c(F)c1O)c1cncnc1N CHEMBL4458811 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCC(F)(F)c3cnc(N)nc3)c(O)c(F)c2Br)C1=O CHEMBL4473869 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCC(=O)Nc3nncs3)c(O)c(F)c2Br)C1=O CHEMBL4439783 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(OCC3(c4cnc(N)nc4)CC3)c(O)c(F)c2Br)C1=O CHEMBL4531995 IC50 500.0 nM
CC(Cc1cnc(N)nc1)Oc1cc(/C=C2\SC(=O)N(C)C2=O)c(Br)c(F)c1O CHEMBL4562478 IC50 500.0 nM
CC(Oc1cc(/C=C2\SC(=O)N(C)C2=O)c(Br)c(F)c1Oc1cnc(N)s1)c1cnc(N)nc1 CHEMBL4442637 IC50 500.0 nM
Cc1nc2c(Oc3cc(/C=C4\SC(=O)N(C)C4=O)c(Br)cc3O)cccc2o1 CHEMBL4548126 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc3c(-c4ccc(N)cc4)c[nH]c3cc2Br)C1=O CHEMBL4586128 IC50 500.0 nM
CSc1ccc(CCc2cc(/C=C3\SC(=O)N(C)C3=O)c(Br)cc2O)cc1 CHEMBL4451693 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(CC(F)(F)F)c(O)cc2Br)C1=O CHEMBL4469511 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(Oc3cnc(N)s3)c(O)c(F)c2Br)C1=O CHEMBL4575253 IC50 500.0 nM
CCC(Oc1cc(/C=C2\SC(=O)N(C)C2=O)c(Br)c(F)c1O)c1cnc(Cl)nc1 CHEMBL4472542 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc3cc[nH]c3c(F)c2Br)C1=O CHEMBL4476601 IC50 500.0 nM
CN1C(=O)S/C(=C\c2cc(CCc3cnc(N)nc3)c(O)cc2Br)C1=O CHEMBL4566708 IC50 500.0 nM