Cn1cnc2c1c(=O)n(CCCn1c(=O)c3nc[nH]c3n(C)c1=O)c(=O)n2C CHEMBL1738785 Ki 1.4 nM
CC[C@H]1CN(C2CCN(c3nc(N)n[nH]3)CC2)[C@@H](Cc2ccc(Cl)cc2)CO1 CHEMBL4776610 IC50 14.0 nM
CC(C)C[C@H]1CN(C2CCN(c3nc(N)n[nH]3)CC2)[C@@H](Cc2ccc(Cl)cc2)CO1 CHEMBL4756869 IC50 16.0 nM
C[C@H]1CN(C2CCN(c3nc(N)n[nH]3)CC2)[C@@H](Cc2ccc(Cl)cc2)CO1 CHEMBL4788866 Ki 17.3 nM
CC(C)[C@H]1CN(C2CCN(c3nc(N)n[nH]3)CC2)[C@@H](Cc2ccc(Cl)cc2)CO1 CHEMBL4794014 IC50 18.0 nM
Nc1n[nH]c(N2CCC(N(CCc3ccc(Cl)cc3)CC3CCCCO3)CC2)n1 CHEMBL4464754 IC50 21.0 nM
Nc1n[nH]c(N2CCC(N3C[C@H](CO)OC[C@@H]3Cc3ccc(Cl)cc3)CC2)n1 CHEMBL4789376 IC50 22.0 nM
COC[C@H]1CN(C2CCN(c3nc(N)n[nH]3)CC2)[C@@H](Cc2ccc(Cl)cc2)CO1 CHEMBL4755139 IC50 22.0 nM
CC(C)(O)[C@H]1CN(C2CCN(c3nc(N)n[nH]3)CC2)[C@@H](Cc2ccc(Cl)cc2)CO1 CHEMBL4764430 IC50 23.0 nM
Nc1n[nH]c(N2CCC(N(CCc3ccc(Cl)cc3)CC3CCCO3)CC2)n1 CHEMBL4541831 IC50 27.0 nM
CNC(=O)[C@H]1CN(C2CCN(c3nc(N)n[nH]3)CC2)[C@@H](Cc2ccc(Cl)cc2)CO1 CHEMBL4749391 IC50 32.0 nM
Nc1n[nH]c(N2CCC(N(CCc3ccc(Cl)cc3)Cc3cccc4ccccc34)CC2)n1 CHEMBL4084573 IC50 36.0 nM
Nc1n[nH]c(N2CCC(N3CCCC[C@@H]3Cc3ccc(Cl)cc3)CC2)n1 CHEMBL4580568 IC50 41.0 nM
CO[C@@H]1C[C@H](Cc2ccc(Cl)cc2)N(C2CCN(c3nc(N)n[nH]3)CC2)C1 CHEMBL4470253 IC50 44.0 nM
CO[C@@H](C)CN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4520755 IC50 44.0 nM
CO[C@H]1C[C@H](Cc2ccc(Cl)cc2)N(C2CCN(c3nc(N)n[nH]3)CC2)C1 CHEMBL4537828 IC50 47.0 nM
Nc1n[nH]c(N2CCC(N3CCOC[C@@H]3Cc3ccc(Cl)cc3)CC2)n1 CHEMBL4461925 IC50 48.0 nM
CC(NC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccccc2)c1=N)c1ccccc1 CHEMBL4549449 Ki 49.0 nM
Nc1nc(N2CCC(N(CCc3ccc(Cl)cc3)Cc3ccccc3O)CC2)n[nH]1 CHEMBL4637417 IC50 49.0 nM
Nc1n[nH]c(N2CCC(N3CCC[C@@H]3Cc3ccc(Cl)cc3)CC2)n1 CHEMBL4588384 IC50 59.0 nM
Nc1nc(N2CCC(N(CCc3ccc(Cl)cc3)Cc3cccc(O)c3)CC2)n[nH]1 CHEMBL4634943 IC50 79.0 nM
Nc1n[nH]c(N2CCC(N3C[C@@H](O)C[C@@H]3Cc3ccc(Cl)cc3)CC2)n1 CHEMBL4442663 IC50 82.0 nM
COCCN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4521547 IC50 84.0 nM
Nc1n[nH]c(N2CCC(N3C[C@H](O)C[C@@H]3Cc3ccc(Cl)cc3)CC2)n1 CHEMBL4547227 IC50 87.0 nM
Nc1nc(N2CCC(N(CCc3ccc(Cl)cc3)Cc3ccc(Cl)cc3)CC2)n[nH]1 CHEMBL4646309 IC50 90.0 nM
Nc1n[nH]c(N2CCC(N(CCc3ccc(Cl)cc3)Cc3ccccc3Cl)CC2)n1 CHEMBL4077644 IC50 104.0 nM
CCN(CCc1ccc(Br)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4098997 IC50 105.0 nM
Nc1n[nH]c(N2CCC(N(CCc3ccc(Cl)cc3)Cc3ccccc3)CC2)n1 CHEMBL4077482 IC50 122.0 nM
CC(C)CN(CCc1ccc(Br)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4068944 IC50 123.0 nM
Nc1n[nH]c(N2CCC(N(CCc3ccc(Cl)cc3)CC3CCCCC3)CC2)n1 CHEMBL4082060 IC50 123.0 nM
CNC(=O)NC(=N)NCC(=O)Nc1ccc([N+](=O)[O-])cc1 CHEMBL5289869 IC50 130.0 nM
C[C@H](O)CN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4464943 IC50 145.0 nM
CN(CCc1ccc(Br)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4086986 IC50 175.0 nM
Nc1nc(N2CCC(N(CCc3ccc(Cl)cc3)Cc3cccc(Cl)c3)CC2)n[nH]1 CHEMBL4649081 IC50 176.0 nM
Nc1n[nH]c(N2CCC(N(CCc3ccc(Cl)cc3)C3COC3)CC2)n1 CHEMBL4440077 IC50 180.0 nM
CNC(=O)NC(=N)NCC(=O)Nc1cccc([N+](=O)[O-])c1 CHEMBL5290116 IC50 190.0 nM
Nc1nc(N2CCC(N(CCc3ccc(Cl)cc3)Cc3ccc(F)cc3Cl)CC2)n[nH]1 CHEMBL4632547 IC50 200.0 nM
CC(C)CN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4076989 IC50 229.0 nM
CN1C[C@H](Cc2ccc(Cl)cc2)N(C2CCN(c3n[nH]c(N)n3)CC2)Cc2ccccc21 CHEMBL4635305 IC50 275.0 nM
Nc1nc(N2CCC(N(CCc3ccc(Cl)cc3)Cc3cc(F)ccc3F)CC2)n[nH]1 CHEMBL4646247 IC50 277.0 nM
Nc1nc(N2CCC(N(CCc3ccc(Cl)cc3)Cc3cccc(C(F)(F)F)c3)CC2)n[nH]1 CHEMBL4642053 IC50 310.0 nM
C[C@@H](O)CN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4460797 IC50 330.0 nM
C=C1COC[C@H](Cc2ccc(Cl)cc2)N(C2CCN(c3n[nH]c(N)n3)CC2)C1 CHEMBL4644319 IC50 350.0 nM
COc1ccc2cc3[n+](cc2c1OC(=O)c1ccc(F)nc1)CCc1cc2c(cc1-3)OCO2 CHEMBL5199149 Ki 350.0 nM
Nc1n[nH]c(N2CCC(N(CCO)CCc3ccc(Cl)cc3)CC2)n1 CHEMBL4577776 IC50 384.0 nM
CCN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4072036 IC50 385.0 nM
CN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4065553 IC50 389.0 nM
CC(C)(O)CN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4446970 IC50 395.0 nM
CN1C[C@H](Cc2ccc(Cl)cc2)N(C2CCN(c3n[nH]c(N)n3)CC2)Cc2cc(Cl)ccc21 CHEMBL4643001 IC50 420.0 nM
CNC(=O)NC(=N)NCC(=O)Nc1cccc(C(F)(F)F)c1 CHEMBL5267352 IC50 490.0 nM
CC(=O)NCCN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4472377 IC50 495.0 nM
COC(C)(C)CN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4546929 IC50 505.0 nM
CO[C@H](C)CN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4442416 IC50 530.0 nM
CO[C@H]1CN(C2CCN(c3nc(N)n[nH]3)CC2)[C@H]1Cc1ccc(Cl)cc1 CHEMBL4466293 IC50 580.0 nM
Nc1nc(N2CCC(N(CCc3ccc(Cl)cc3)Cc3ccncc3Cl)CC2)n[nH]1 CHEMBL4637250 IC50 620.0 nM
CNC(=O)NC(=N)NCc1cn(CCCC(=O)N2CCCCCCCC(=O)OCC2)nn1 CHEMBL5276579 IC50 660.0 nM
CNC(=O)NC(=N)NCC(=O)Nc1ccccc1OC CHEMBL5282035 IC50 680.0 nM
CNC(=O)NC(=N)NCC(=O)Nc1ccc(F)cc1C CHEMBL5281117 IC50 680.0 nM
CN(CCc1ccc(C2CC2)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4091907 IC50 765.0 nM
CNS(=O)(=O)CCN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4453964 IC50 870.0 nM
CNC(=O)NC(=N)NCC(=O)Nc1ccccn1 CHEMBL5277135 IC50 870.0 nM
Nc1nc(N2CCC(N3Cc4ccccc4OC[C@@H]3Cc3ccc(Cl)cc3)CC2)n[nH]1 CHEMBL4640857 IC50 915.0 nM
Nc1nc(N2CCC(N3Cc4cc(F)ccc4OC[C@@H]3Cc3ccc(Cl)cc3)CC2)n[nH]1 CHEMBL4648962 IC50 930.0 nM
CC(C)N(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 CHEMBL4075848 IC50 945.0 nM
CCOc1ccc(NC(=O)CNC(=N)NC(=O)NC)cc1 CHEMBL5276002 IC50 960.0 nM