O=C(c1occc1Br)N1CC2CNCC2C1 CHEMBL2179534 Ki 1.5 nM
O=C(c1cc(Br)c(Br)o1)N1CC2CNCC(C2)C1 CHEMBL3676980 Ki 1.6 nM
O=C(c1cc(Br)co1)N1CC2CNCC(C2)C1 CHEMBL2179547 Ki 1.7 nM
O=C(c1occc1Cl)N1CC2CNCC2C1 CHEMBL2179531 Ki 2.4 nM
O=C(c1ccc(F)o1)N1CC2CNCC(C2)C1 CHEMBL2179540 Ki 4.6 nM
O=C(c1cc(Br)c(Br)o1)N1CC2CNCC2C1 CHEMBL3676962 Ki 4.9 nM
Cc1oc(C(=O)N2CC3CNCC(C3)C2)cc1Br CHEMBL3676982 Ki 5.2 nM
O=C(c1cc(Cl)co1)N1CC2CNCC(C2)C1 CHEMBL2179544 Ki 5.2 nM
O=C(c1ccc(Cl)o1)N1CC2CNCC(C2)C1 CHEMBL2179543 Ki 7.3 nM
[C-]#[N+]c1ccc(C(=O)N2CC3CNCC(C3)C2)o1 CHEMBL3676986 Ki 8.7 nM
Cc1ncoc1C(=O)N1CC2CNCC2C1 CHEMBL2179516 Ki 9.2 nM
O=C(c1cc(Cl)co1)N1CC2CNCC2C1 CHEMBL2179530 Ki 9.7 nM
O=C(c1ccco1)N1CC2CNCC(C2)C1 CHEMBL2179967 Ki 9.9 nM
O=C(c1ccon1)N1CC2CNCC(C2)C1 CHEMBL3676981 Ki 10.0 nM
O=C(c1cc(F)co1)N1CC2CNCC(C2)C1 CHEMBL2179541 Ki 14.0 nM
Cc1nocc1C(=O)N1CC2CNCC2C1 CHEMBL3676951 Ki 14.0 nM
Cc1cc(F)c(C(=O)N2CC3CNCC3C2)o1 CHEMBL3676967 Ki 14.0 nM
[C-]#[N+]c1ccoc1C(=O)N1CC2CNCC2C1 CHEMBL3676963 Ki 14.0 nM
O=C(c1ccc(F)o1)N1CC2CNCC2C1 CHEMBL2179526 Ki 16.0 nM
O=C(c1occc1Br)N1CC2CNCC(C2)C1 CHEMBL2179548 Ki 17.0 nM
O=C(c1cc(Br)no1)N1CC2CNCC(C2)C1 CHEMBL3676970 Ki 18.0 nM
O=C(c1ccncc1)N1CC2CNCC(C2)C1 CHEMBL2179524 Ki 18.0 nM
O=C(c1cc(Br)co1)N1CC2CNCC2C1 CHEMBL2179533 Ki 18.0 nM
COc1cc(C(=O)N2CC3CNCC3C2)on1 CHEMBL3676943 Ki 19.0 nM
Cc1nocc1C(=O)N1CC2CNCC(C2)C1 CHEMBL3676974 Ki 21.0 nM
O=C(c1cc(F)co1)N1CC2CNCC2C1 CHEMBL2179527 Ki 21.0 nM
CCCCC#Cc1coc(C(=O)N2CC3CNCC3C2)c1 CHEMBL3676961 Ki 21.0 nM
Cc1oc(C(=O)N2CC3CNCC3C2)cc1Br CHEMBL3676959 Ki 22.0 nM
O=C(c1cc(-c2cc(F)cc(F)c2)co1)N1CC2CNCC(C2)C1 CHEMBL3676978 Ki 23.0 nM
[C-]#[N+]c1coc(C(=O)N2CC3CNCC(C3)C2)c1 CHEMBL3676989 Ki 23.0 nM
O=C(c1cc(-c2cc(F)cc(F)c2)co1)N1CC2CNCC2C1 CHEMBL3676947 Ki 24.0 nM
O=C(c1cnco1)N1CC2CNCC(C2)C1 CHEMBL3676984 Ki 26.0 nM
O=C(c1occc1F)N1CC2CNCC2C1 CHEMBL2179528 Ki 27.0 nM
Nc1coc(C(=O)N2CC3CNCC3C2)c1 CHEMBL3676958 Ki 28.0 nM
COc1ccoc1C(=O)N1CC2CNCC(C2)C1 CHEMBL3676983 Ki 28.0 nM
Cc1ccc(C(=O)N2CC3CNCC3C2)o1 CHEMBL2179538 Ki 28.0 nM
O=C(c1ccc(Cl)o1)N1CC2CNCC2C1 CHEMBL2179529 Ki 28.0 nM
O=C(c1occc1Cl)N1CC2CNCC(C2)C1 CHEMBL2179545 Ki 29.0 nM
Cc1occc1C(=O)N1CC2CNCC2C1 CHEMBL3676953 Ki 29.0 nM
O=C(c1ccno1)N1CC2CNCC(C2)C1 CHEMBL3676991 Ki 30.0 nM
Cc1oncc1C(=O)N1CC2CNCC(C2)C1 CHEMBL3676990 Ki 31.0 nM
Cc1cc(C(=O)N2CC3CNCC3C2)on1 CHEMBL3676952 Ki 31.0 nM
O=C(c1ccc([N+](=O)[O-])o1)N1CC2CNCC2C1 CHEMBL3676942 Ki 31.0 nM
N#Cc1ccoc1C(=O)N1CC2CNCC(C2)C1 CHEMBL2179551 Ki 31.0 nM
O=C(c1ccco1)N1CC2CNCC2C1 CHEMBL2179966 Ki 33.0 nM
O=C(c1cc(-c2ccoc2)co1)N1CC2CNCC(C2)C1 CHEMBL3676979 Ki 35.0 nM
O=C(c1cc(C(F)(F)F)co1)N1CC2CNCC2C1 CHEMBL3676957 Ki 36.0 nM
COc1coc(C(=O)N2CC3CNCC3C2)c1OC CHEMBL3676946 Ki 40.0 nM
[C-]#[N+]c1ccc(C(=O)N2CC3CNCC3C2)o1 CHEMBL3676966 Ki 40.0 nM
Cc1ccc(C(=O)N2CC3CNCC(C3)C2)o1 CHEMBL2179552 Ki 42.0 nM
O=C(c1ccc(C#Cc2ccccc2)o1)N1CC2CNCC2C1 CHEMBL3676944 Ki 43.0 nM
O=C(c1cc(Br)no1)N1CC2CNCC2C1 CHEMBL3676945 Ki 44.0 nM
Cc1cc(C(F)(F)F)c(C(=O)N2CC3CNCC3C2)o1 CHEMBL3676956 Ki 45.0 nM
Cc1cc(C(=O)N2CC3CNCC(C3)C2)on1 CHEMBL3676975 Ki 47.0 nM
C#Cc1ccc(C(=O)N2CC3CNCC(C3)C2)o1 CHEMBL3676985 Ki 47.0 nM
C#Cc1ccc(C(=O)N2CC3CNCC3C2)o1 CHEMBL3676965 Ki 48.0 nM
C=Cc1ccoc1C(=O)N1CC2CNCC2C1 CHEMBL3676960 Ki 51.0 nM
O=C(c1ccc(Br)o1)N1CC2CNCC(C2)C1 CHEMBL2179546 Ki 51.0 nM
CN1CCC(S(=O)(=O)c2ccc3nc(NC(=O)NC(=O)c4cc(N5CCOCC5)ccc4Cl)sc3c2)CC1 CHEMBL3319405 Ki 52.0 nM
Cc1ccoc1C(=O)N1CC2CNCC2C1 CHEMBL2179539 Ki 54.0 nM
O=C(c1occc1F)N1CC2CNCC(C2)C1 CHEMBL2179542 Ki 57.0 nM
Nc1coc(C(=O)N2CC3CNCC(C3)C2)c1 CHEMBL3676977 Ki 62.0 nM
Cc1cc(F)c(C(=O)N2CC3CNCC(C3)C2)o1 CHEMBL3676987 Ki 62.0 nM
O=CNc1ccc(C(=O)N2CC3CNCC3C2)o1 CHEMBL3676954 Ki 63.0 nM
Cc1ncoc1C(=O)N1CC2CNCC(C2)C1 CHEMBL3676973 Ki 64.0 nM
O=C(c1ccno1)N1CC2CNCC2C1 CHEMBL2179956 Ki 69.0 nM
O=C(c1ccc(Br)o1)N1CC2CNCC2C1 CHEMBL2179532 Ki 73.0 nM
O=C(c1cc(C2CC2)on1)N1CC2CNCC(C2)C1 CHEMBL3676976 Ki 83.0 nM
Cc1cc(C(=O)N2CC3CNCC3C2)no1 CHEMBL3676950 Ki 84.0 nM
O=C(c1ncco1)N1CC2CNCC(C2)C1 CHEMBL3676988 Ki 85.0 nM
O=C(c1cc(-c2ccccc2)co1)N1CC2CNCC2C1 CHEMBL3676948 Ki 86.0 nM
O=C(c1ccon1)N1CC2CNCC2C1 CHEMBL3676964 Ki 90.0 nM
c1cnc2cc3c(cc2n1)[C@@H]1CNC[C@H]3C1 CHEMBL1076903 AC50 91.0 nM
O=C(c1cc(-c2ccoc2)co1)N1CC2CNCC2C1 CHEMBL3676949 Ki 95.0 nM
Cc1cc(C(=O)N2CC3CNCC(C3)C2)no1 CHEMBL3676972 Ki 96.0 nM
COc1ccoc1C(=O)N1CC2CNCC2C1 CHEMBL3676955 Ki 100.0 nM
O=C(c1coc(C(F)F)c1)N1CC2CNCC2C1 CHEMBL3676968 Ki 130.0 nM
O=C(c1ccncc1)N1CC2CNCC2C1 CHEMBL2179971 Ki 160.0 nM
COc1cc(C(=O)N2CC3CNCC(C3)C2)on1 CHEMBL3676969 Ki 180.0 nM
CC(=O)Nc1ccc(C(=O)N2CC3CNCC(C3)C2)o1 CHEMBL3676971 Ki 210.0 nM
O=C(c1ccoc1)N1CC2CNCC2C1 CHEMBL2179559 Ki 220.0 nM
Cc1ccc(NC(=O)c2cc(-c3ccccc3)c(N3CCOCC3)s2)c(C)c1 CHEMBL1210703 pIC50 1000.0 nM