CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL388978 Kd 5.8 nM
O=S1(=O)CCC(NS(=O)(=O)c2ccc(-c3ccnc4[nH]c(C5CC5)cc34)cc2)CC1 CHEMBL2164412 pIC50 6.31 nM
CC(C)c1cc2c(-c3ccc(S(=O)(=O)NC4CCS(=O)(=O)CC4)cc3)ccnc2[nH]1 CHEMBL2164411 pIC50 6.31 nM
CCc1cc2c(-c3ccc(S(=O)(=O)NC4CCS(=O)(=O)CC4)cc3)ccnc2[nH]1 CHEMBL2164410 pIC50 6.31 nM
CNc1nc2[nH]c(-c3cccc(F)c3)cc2c2c1ncn2C CHEMBL549478 IC50 7.0 nM
CNc1nc2[nH]c(-c3cccc(C#N)c3)cc2c2c1ncn2C CHEMBL558491 IC50 7.0 nM
Cc1cc2c(-c3ccc(S(=O)(=O)NC4CCS(=O)(=O)CC4)nc3)ccnc2[nH]1 CHEMBL2164417 pIC50 7.943 nM
CNc1nc2[nH]c(-c3cccc(OC)c3)cc2c2c1ncn2C CHEMBL551773 IC50 8.0 nM
C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)CNC4=O CHEMBL603469 Kd 9.0 nM
Oc1ccccc1-c1nc(-c2ccc(C(F)(F)F)cc2)no1 CHEMBL4859206 IC50 10.58 nM
CNc1nc2[nH]c(-c3cccc(CN)c3)cc2c2c1ncn2C CHEMBL562720 IC50 11.0 nM
Oc1ccccc1-c1nc(-c2ccccc2)no1 CHEMBL1876217 IC50 11.0 nM
CNc1nc2[nH]c(-c3cccc(CNC(=O)CCOC)c3)cc2c2c1ncn2C CHEMBL562971 IC50 12.0 nM
Cc1cc2c(-c3ccc(S(=O)(=O)NC4CCS(=O)(=O)CC4)cc3)ccnc2[nH]1 CHEMBL483165 pIC50 12.59 nM
CNc1nc2[nH]c(-c3cccc(CNC(C)=O)c3)cc2c2c1ncn2C CHEMBL552183 IC50 14.0 nM
Oc1ccccc1-c1nc(Cc2ccccc2)no1 CHEMBL4849098 IC50 15.94 nM
CNc1nc2[nH]c(-c3cccc(CNC(=O)CCC(N)=O)c3)cc2c2c1ncn2C CHEMBL562370 IC50 22.0 nM
N#Cc1c(C2CCCNC2)cc(-c2ccccc2O)nc1N CHEMBL360077 IC50 25.0 nM
CNc1nc2[nH]c(-c3cccc(CNC(=O)CO)c3)cc2c2c1ncn2C CHEMBL561447 IC50 25.0 nM
CC(C)(C)c1cc2c(-c3ccc(S(=O)(=O)NC4CCS(=O)(=O)CC4)cc3)ccnc2[nH]1 CHEMBL2164413 pIC50 25.12 nM
CCC(N)(CC)CCc1ccc(-c2ccnc(Nc3ccc(C(=O)N4CCC(N5CCCC5)CC4)cc3)n2)s1 CHEMBL382945 IC50 30.0 nM
CC(C)(N)CCc1ccc(-c2ccnc(Nc3ccc(C(=O)N4CCC(N5CCCC5)CC4)cc3)n2)s1 CHEMBL199837 IC50 30.0 nM
O=S(=O)(NC1CNC1)c1ccc(-c2ccnc3[nH]ccc23)cc1 CHEMBL482540 pIC50 31.62 nM
O=S1(=O)CCC(NS(=O)(=O)c2ccc(-c3ccnc4[nH]c(C5CCNCC5)cc34)cc2)CC1 CHEMBL2164415 pIC50 31.62 nM
CS(=O)(=O)Nc1ccc(-c2cc3c(-c4ccc(C(N)=O)cc4)ccnc3[nH]2)cc1 CHEMBL4128114 pIC50 31.62 nM
NCc1ccc(-c2cnc3[nH]cc(-c4cccc(NC(=O)Nc5ccc(C(F)(F)F)cc5F)c4)c3c2)cc1 CHEMBL551024 IC50 32.0 nM
NCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc21 CHEMBL590109 IC50 33.0 nM
CNc1nc2[nH]c(-c3cccc(CNC(=O)c4csnn4)c3)cc2c2c1ncn2C CHEMBL560708 IC50 39.0 nM
CNc1nc2[nH]c(-c3ccccc3)cc2c2c1ncn2C CHEMBL565076 IC50 40.0 nM
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1 CHEMBL574738 Kd 41.0 nM
CNc1nc2[nH]c(-c3ccc(F)cc3)cc2c2c1ncn2C CHEMBL549479 IC50 43.0 nM
CNc1nc2[nH]c(-c3ccccc3F)cc2c2c1ncn2C CHEMBL556806 IC50 44.0 nM
Cn1cc(/C=C2\Oc3cccc(O)c3C2=O)c2c(-c3ccc(C(=O)NCCO)cc3)ccnc21 CHEMBL1092754 IC50 50.0 nM
O=S1(=O)CCC(NS(=O)(=O)c2ccc(-c3ccnc4[nH]ccc34)cc2)CC1 CHEMBL482746 pIC50 50.12 nM
CNC1CC2OC(C)(C1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 CHEMBL1980995 pKi 50.12 nM
O=S1(=O)CCC(NS(=O)(=O)c2ccc(-c3ccnc4[nH]c(Cn5ccnn5)cc34)cc2)CC1 CHEMBL2164416 pIC50 50.12 nM
CNc1nc2[nH]c(-c3cccc(CNC(=O)CN(C)C)c3)cc2c2c1ncn2C CHEMBL563554 IC50 79.0 nM
NC(=O)c1cc(-c2ccncc2)cc(-c2ccc(S(N)(=O)=O)cc2)c1N CHEMBL397009 pIC50 79.43 nM
Cc1cc2c(-c3ccc(S(=O)(=O)NC4CCS(=O)(=O)CC4)cn3)ccnc2[nH]1 CHEMBL2164418 pIC50 79.43 nM
CN(C)Cc1ccc(-c2cc3c(-c4ccc(C(N)=O)cc4)ccnc3[nH]2)cc1 CHEMBL4125907 pIC50 79.43 nM
CN(C)Cc1cccc(-c2cc3c(-c4ccc(C(N)=O)cc4)ccnc3[nH]2)c1 CHEMBL4125774 pIC50 79.43 nM
CN(C)CCCNC(=O)c1ccc(-c2cc3c(-c4ccc(C(N)=O)cc4)ccnc3[nH]2)cc1 CHEMBL4127140 pIC50 79.43 nM
Clc1cc2c3cc[nH]cc-3nc2c(Cl)c1OCC1CC1 CHEMBL81603 IC50 80.0 nM
N#Cc1c[nH]c2nc(N)nc(-c3ccc(S(N)(=O)=O)cc3)c12 CHEMBL4089551 Ki 80.0 nM
CCCc1cc(N2CCC(N)CC2)nc2sc(C(N)=O)c(N)c12 CHEMBL578601 IC50 90.0 nM
O=C(Nc1cc(Cl)cc2c1[nH]c1cnccc12)c1cccnc1 CHEMBL79004 IC50 100.0 nM
COc1cc(Nc2nccc(-c3cc4ccccc4s3)n2)ccc1C(=O)N1CCC(N2CCCC2)CC1 CHEMBL372736 IC50 100.0 nM
Nc1nccc(-c2ccc3c(N)n[nH]c3c2)n1 CHEMBL1688215 IC50 100.0 nM
Nc1ncnc2c1N=C(c1ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc1)CCN2 CHEMBL260092 pKi 100.0 nM
CN(C)Cc1cc2c(-c3ccc(S(=O)(=O)NC4CCS(=O)(=O)CC4)cc3)ccnc2[nH]1 CHEMBL2164414 pIC50 100.0 nM
Cc1c(CN2CCOCC2)cccc1-c1cc2c(-c3ccc(C(N)=O)cc3)ccnc2[nH]1 CHEMBL4128939 pIC50 100.0 nM
COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC CHEMBL475251 Kd 120.0 nM
Cc1cc2c(-c3ccc(S(=O)(=O)NCCN)cc3)ccnc2[nH]1 CHEMBL482747 pIC50 125.89 nM
Cc1cc2c(-c3ccc(NS(=O)(=O)CCN)cc3)ccnc2[nH]1 CHEMBL520473 pIC50 125.89 nM
O=C1NCCc2[nH]c(-c3ccnc(C=Cc4ccccc4)c3)cc21 CHEMBL1997129 pKi 125.89 nM
CN(C)CCCNC(=O)c1cccc(-c2cc3c(-c4ccc(C(N)=O)cc4)ccnc3[nH]2)c1 CHEMBL4126740 pIC50 125.89 nM
Cc1cc(CN2CCOCC2)ccc1-c1cc2c(-c3ccc(C(N)=O)cc3)ccnc2[nH]1 CHEMBL4130310 pIC50 125.89 nM
Cc1cc(OCCN2CCOCC2)ccc1-c1cc2c(-c3ccc(C(N)=O)cc3)ccnc2[nH]1 CHEMBL4126095 pIC50 125.89 nM
CNc1nc2cc(-c3cccc(CCNC(N)=O)c3)sc2n2c(C)cnc12 CHEMBL249481 IC50 130.0 nM
CCOc1c(Cl)cc2c3cc[nH]cc-3nc2c1Cl CHEMBL81229 IC50 140.0 nM
O=C(Nc1ccc(-c2ccnc(Nc3ccc4ncsc4c3)n2)cc1)C1CCCN1 CHEMBL254556 IC50 146.0 nM
CN(C)C1CCN(C(=O)c2ccc(Nc3nccc(-c4cc5ccccc5s4)n3)cc2)CC1 CHEMBL200229 IC50 150.0 nM
NC(=O)c1c[nH]c2ccc(-c3ccc(Nc4nccc(-c5ccc(S(=O)(=O)N6CCNCC6)cc5)n4)cc3)cc12 CHEMBL337236 IC50 154.0 nM
COc1cc(Nc2nccc(-c3ccc(S(=O)(=O)N4CCNCC4)cc3)n2)cc(OC)c1OC CHEMBL132942 IC50 155.0 nM
NS(=O)(=O)c1ccc(-c2ccnc3[nH]ccc23)cc1 CHEMBL519028 pIC50 158.49 nM
NCCNS(=O)(=O)c1ccc(-c2ccnc3[nH]c(CC(N)=O)cc23)cc1 CHEMBL519965 pIC50 158.49 nM
Cc1cc2c(-c3ncc(S(=O)(=O)NC4CCS(=O)(=O)CC4)cn3)ccnc2[nH]1 CHEMBL2164419 pIC50 158.49 nM
CS(=O)(=O)Nc1cccc(-c2cc3c(-c4ccc(C(N)=O)cc4)ccnc3[nH]2)c1 CHEMBL4127977 pIC50 158.49 nM
COc1ccccc1-c1cc2c(-c3ccc(C(N)=O)cc3)ccnc2[nH]1 CHEMBL4129362 pIC50 158.49 nM
Cc1c(OCCN2CCOCC2)cccc1-c1cc2c(-c3ccc(C(N)=O)cc3)ccnc2[nH]1 CHEMBL4128717 pIC50 158.49 nM
Cc1ccc(CN2CCOCC2)cc1-c1cc2c(-c3ccc(C(N)=O)c(C(C)C)c3)ccnc2[nH]1 CHEMBL4129791 pIC50 158.49 nM
COc1c(Cl)cc2c3cc[nH]cc-3nc2c1Cl CHEMBL312651 IC50 170.0 nM
CNc1nc2cc(-c3cccc(CNS(N)(=O)=O)c3)sc2n2c(C)cnc12 CHEMBL249280 IC50 170.0 nM
O=C(c1ccc(/C=C/c2n[nH]c3ccccc23)cc1)N1CCNCC1 CHEMBL1908397 Kd 180.0 nM
CNc1nc2cc(-c3cccc(C[C@@H](N)C(N)=O)c3)sc2n2c(C)cnc12 CHEMBL249887 IC50 190.0 nM
Cc1cc2c(-c3ccc(S(=O)(=O)NCC(C)(C)O)cc3)ccnc2[nH]1 CHEMBL2164425 pIC50 199.53 nM
O=S(=O)(NCCO)c1ccc(-c2ccnc3[nH]c(C4CC4)cc23)cc1 CHEMBL2164422 pIC50 199.53 nM
O=S(=O)(NCCO)c1ccc(-c2ccnc3[nH]c(C(F)(F)F)cc23)cc1 CHEMBL2164420 pIC50 199.53 nM
Cc1ccc(OCCN2CCOCC2)cc1-c1cc2c(-c3ccc(C(N)=O)cc3)ccnc2[nH]1 CHEMBL4127479 pIC50 199.53 nM
Clc1cc(Cl)c2[nH]c3cnccc3c2c1 CHEMBL78464 IC50 200.0 nM
O=C(c1ccc(Nc2nccc(-c3cc4ccccc4s3)n2)cc1)N1CCC(N2CCCC2)CC1 CHEMBL200027 IC50 200.0 nM
CNc1nc2cc(-c3cccc(CN)c3)sc2n2c(C)cnc12 CHEMBL400077 IC50 220.0 nM
CNc1nc2cc3ccccc3cc2n2c(C)cnc12 CHEMBL231530 IC50 230.0 nM
CNc1nc2sc(-c3cccc([C@H](C)NC(C)=O)c3)nc2c2c1ncn2C CHEMBL1642545 IC50 230.0 nM
NS(=O)(=O)c1ccc(Nc2nccc(-c3ccc(S(=O)(=O)N4CCNCC4)cc3)n2)cc1 CHEMBL131693 IC50 245.0 nM
N#Cc1c(C2CCNCC2)cc(-c2c(O)cccc2OCC2CC2)nc1N CHEMBL368427 IC50 250.0 nM
O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cc(Cl)ccc1O CHEMBL536151 IC50 250.0 nM
NCCNS(=O)(=O)c1ccc(-c2ccnc3[nH]ccc23)cc1 CHEMBL473080 pIC50 251.19 nM
CCn1c(C)c(-c2ccnc(Nc3cccc(OC)c3)n2)sc1=O CHEMBL1986263 pKi 251.19 nM
C[C@@H](CO)NS(=O)(=O)c1ccc(-c2ccnc3[nH]c(C4CC4)cc23)cc1 CHEMBL2164426 pIC50 251.19 nM
CNc1nc2cc(-c3cccc(C[C@H](N)C(N)=O)c3)sc2n2c(C)cnc12 CHEMBL399689 IC50 260.0 nM
CNc1nc2cc(-c3cccc(CNC(N)=O)c3)sc2n2c(C)cnc12 CHEMBL400078 IC50 260.0 nM
CNc1nc2oc(-c3ccccc3)nc2c2c1ncn2C CHEMBL493940 IC50 270.0 nM
O=C(Nc1cc(Cl)cc2c1[nH]c1cnccc12)c1ccncc1 CHEMBL80843 IC50 300.0 nM
CNCCNS(=O)(=O)c1ccc(-c2ccnc3[nH]ccc23)cc1 CHEMBL482539 pIC50 316.23 nM
Cc1cc2c(-c3ccc(S(=O)(=O)NCCO)cc3)ccnc2[nH]1 CHEMBL483557 pIC50 316.23 nM
Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4c[nH]c5ccccc45)c3)cc12 CHEMBL1970903 pKi 316.23 nM
C[C@@H](CO)NS(=O)(=O)c1ccc(-c2ccnc3[nH]c(C(F)(F)F)cc23)cc1 CHEMBL2164427 pIC50 316.23 nM
CC(C)(O)CNS(=O)(=O)c1ccc(-c2ccnc3[nH]c(C4CC4)cc23)cc1 CHEMBL2164424 pIC50 316.23 nM
CNC(=O)C(N)Cc1cccc(-c2cc3nc(NC)c4ncc(C)n4c3s2)c1 CHEMBL399368 IC50 330.0 nM
CN1CCN(Cc2ccc(-c3cnc4[nH]cc(-c5cnc6[nH]ccc6c5)c4c3)cc2)CC1 CHEMBL2436977 IC50 330.0 nM
CS(=O)(=O)Nc1ccc(Nc2nccc(-c3ccc(S(=O)(=O)N4CCNCC4)cc3)n2)cc1 CHEMBL133823 IC50 331.0 nM
CCn1nc(C#Cc2cc(C(=O)Nc3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)ccc2C)c2c(N)ncnc21 CHEMBL3426225 IC50 353.0 nM
CNCCNc1nc2cc3ccccc3cc2n2c(C)cnc12 CHEMBL536520 IC50 390.0 nM
CNc1nc2cc(-c3cccc(CCNCC(N)=O)c3)sc2n2c(C)cnc12 CHEMBL398253 IC50 390.0 nM
NC(=O)c1cc(-c2ccc(Cl)cc2)cc(-c2ccc(S(N)(=O)=O)cc2)c1N CHEMBL230488 pIC50 398.11 nM
NC(=O)c1ccc(-c2ccnc3[nH]ccc23)cc1 CHEMBL504261 pIC50 398.11 nM
NC(COc1cncc(-c2ccc3c(c2)C(=Cc2ccco2)C(=O)N3)c1)Cc1c[nH]c2ccccc12 CHEMBL2001751 pKi 398.11 nM
CC(C)c1cc2c(-c3ccc(S(=O)(=O)NCCO)cc3)ccnc2[nH]1 CHEMBL2164421 pIC50 398.11 nM
O=C(c1ccc(Nc2nccc(-c3cc4ccccc4s3)n2)cc1Cl)N1CCC(N2CCCC2)CC1 CHEMBL199980 IC50 400.0 nM
Cc1cnc2c(NCCN)nc3cc(-c4ccccc4)sc3n12 CHEMBL249901 IC50 400.0 nM
CNCCNc1nc2cc3ccccc3cc2n2c(C)cnc12 CHEMBL249899 IC50 420.0 nM
CCNc1nc2sc(-c3cccc([C@H](C)NC(C)=O)c3)nc2c2c1ncn2C CHEMBL1642546 IC50 420.0 nM
CNc1nc2sc(-c3cccc(C(C)NC(C)=O)c3)nc2c2c1ncn2C CHEMBL1642549 IC50 430.0 nM
CNc1nc2cc(-c3cccc(CCNS(N)(=O)=O)c3)sc2n2c(C)cnc12 CHEMBL249482 IC50 440.0 nM
Cc1cnc2c(NCCN)nc3cc(-c4cccc(CO)c4)sc3n12 CHEMBL249104 IC50 450.0 nM
CC(C)(N)C#Cc1ccc(-c2ccnc(Nc3ccc(C(=O)N4CCC(N5CCCC5)CC4)cc3)n2)s1 CHEMBL381041 IC50 500.0 nM
O=C(c1ccc(Nc2nccc(-c3ccc(CCCCO)s3)n2)cc1)N1CCC(N2CCCC2)CC1 CHEMBL200106 IC50 500.0 nM
NC(=O)c1cc(-c2ccc(F)cc2)cc(-c2ccc(S(N)(=O)=O)cc2)c1N CHEMBL230276 pIC50 501.19 nM
CC(=NNC(=N)N)c1cc(NC(=O)NCCCCCCNC(=O)Nc2cc(C(C)=NNC(=N)N)cc(C(C)=NNC(=N)N)c2)cc(C(C)=NNC(=N)N)c1 CHEMBL1991728 pKi 501.19 nM
CC(=NNC(=N)N)c1cc(NC(=O)c2cccc(C(=O)Nc3cc(C(C)=NNC(=N)N)cc(C(C)=NNC(=N)N)c3)c2)cc(C(C)=NNC(=N)N)c1 CHEMBL2000685 pKi 501.19 nM
CNc1nc2cc(-c3cccc(CNCC(N)=O)c3)sc2n2c(C)cnc12 CHEMBL428754 IC50 510.0 nM
CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c1C CHEMBL535 Kd 520.0 nM
CN1CCN(Cc2ccc(-c3cnc4[nH]cc(-c5ccc6[nH]ccc6c5)c4c3)cc2)CC1 CHEMBL2436978 IC50 591.0 nM
COc1cccc(C(=O)Nc2cc(Cl)cc3c4cc[nH]cc-4nc23)c1 CHEMBL310179 IC50 600.0 nM
CC(=O)Nc1cc(Cl)cc2c3cc[nH]cc-3nc12 CHEMBL80121 IC50 600.0 nM
Clc1ccc2[nH]c3cnccc3c2c1 CHEMBL311201 IC50 600.0 nM
Brc1ccc2[nH]c3cnccc3c2c1 CHEMBL81169 IC50 600.0 nM
NCCNNS(=O)(=O)c1ccc(-c2cc(-c3ccccc3)cc(C(N)=O)c2N)cc1 CHEMBL230047 pIC50 630.96 nM
NC(Cc1c[nH]c2ccccc12)C(=O)Nc1cncc(C=Cc2ccncc2)c1 CHEMBL1983945 pKi 630.96 nM
NC(COc1cncc(C=Cc2ccncc2)c1)Cc1c[nH]c2ccccc12 CHEMBL1974935 pKi 630.96 nM
CNc1nc2cc(-c3cccc(CCN)c3)sc2n2c(C)cnc12 CHEMBL437586 IC50 650.0 nM
N#Cc1c[nH]c2nc(N)nc(-c3ccc(CO)cc3)c12 CHEMBL4088616 Ki 650.0 nM
CNc1nc2cc3ccccc3cc2c2c(C)cnn12 CHEMBL390201 IC50 670.0 nM
Cc1[nH]c(/C=C2\C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1 CHEMBL1721885 Kd 670.0 nM
CNc1nc2cc(-c3cccc(CC(N)=O)c3)sc2n2c(C)cnc12 CHEMBL399486 IC50 680.0 nM
COc1cccc(-c2cc3nc(NCCN)c4ncc(C)n4c3s2)c1 CHEMBL249102 IC50 690.0 nM
COC(=O)Nc1cc(Cl)cc2c3cc[nH]cc-3nc12 CHEMBL312698 IC50 700.0 nM
O=C(Nc1cc(Cl)cc2c1[nH]c1cnccc12)c1ccccc1 CHEMBL78862 IC50 700.0 nM
CC(C)(O)CCc1ccc(-c2ccnc(Nc3ccc(C(=O)N4CCC(N5CCCC5)CC4)cc3)n2)s1 CHEMBL371543 IC50 700.0 nM
NCCC(=O)Nc1ccc(-c2ccnc(Nc3ccc4ncsc4c3)n2)cc1 CHEMBL254793 IC50 731.0 nM
CNc1nc2cc(-c3cccc(CNC(C)=O)c3)sc2n2c(C)cnc12 CHEMBL249279 IC50 770.0 nM
NC(=O)c1cc(-c2ccccc2)cc(-c2ccc(S(=O)(=O)NNCCN3CCCC3)cc2)c1N CHEMBL231129 pIC50 794.33 nM
COCCCNNS(=O)(=O)c1ccc(-c2cc(-c3ccccc3)cc(C(N)=O)c2N)cc1 CHEMBL426532 pIC50 794.33 nM
CN(C)CCNS(=O)(=O)c1ccc(-c2ccnc3[nH]ccc23)cc1 CHEMBL520954 pIC50 794.33 nM
CS(=O)(=O)Nc1ccc(-c2ccnc3[nH]ccc23)cc1 CHEMBL453707 pIC50 794.33 nM
OCCCNc1ncnc2[nH]cc(-c3ccccc3)c12 CHEMBL2000071 pKi 794.33 nM
CC(C)(C)c1cc2c(-c3ccc(S(=O)(=O)NCCO)cc3)ccnc2[nH]1 CHEMBL2164423 pIC50 794.33 nM
N#Cc1c[nH]c2nc(N)nc(N[C@@H]3C[C@H](O)[C@@H](O)[C@H]3O)c12 CHEMBL4086169 Ki 800.0 nM
CNc1nc2cc(-c3cccc(CCNC(C)=O)c3)sc2n2c(C)cnc12 CHEMBL249480 IC50 820.0 nM
Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 CHEMBL1287853 Kd 830.0 nM
CNC(=O)c1nc2c(nc(NC)c3ncn(C)c32)s1 CHEMBL504727 IC50 840.0 nM
O=S(=O)(c1ccc(-c2ccnc(Nc3ccc4ncsc4c3)n2)cc1)N1CCNCC1 CHEMBL257805 IC50 850.0 nM
O=S(=O)(c1ccc(-c2ccnc(Nc3ccc(-c4ccc5ncsc5c4)cc3)n2)cc1)N1CCNCC1 CHEMBL129981 IC50 851.0 nM
Cc1cnc2c(NCCO)nc3cc4ccccc4cc3n12 CHEMBL230184 IC50 870.0 nM
Cc1cnc2c(NCCN)nc3cc(-c4cccc(CCO)c4)sc3n12 CHEMBL249515 IC50 910.0 nM
Cc1cnc2c(NCCN)nc3cc(-c4ccoc4)sc3n12 CHEMBL249902 IC50 940.0 nM
CC(=O)Nc1cc(N)c(C#N)c(-c2ccccc2)n1 CHEMBL210032 Ki 970.0 nM
CNc1nc2cc3ccccc3cc2c2c1ncn2C CHEMBL231036 IC50 990.0 nM
CNc1nc2cc(-c3ccccc3)nn2c2c1ncn2C CHEMBL493745 IC50 990.0 nM
COc1ccc2[nH]c3cnccc3c2c1Br CHEMBL310975 IC50 1000.0 nM
O=C(Nc1cc(Cl)cc2c1[nH]c1cnccc12)c1ccccn1 CHEMBL78917 IC50 1000.0 nM
COCCCc1ccc(-c2ccnc(Nc3ccc(C(=O)N4CCC(N5CCCC5)CC4)cc3)n2)s1 CHEMBL200462 IC50 1000.0 nM
NC(=O)c1cc(-c2ccccc2)cc(-c2ccc(S(=O)(=O)NNC3CC3)cc2)c1N CHEMBL388646 pIC50 1000.0 nM
NC(=O)c1cc(-c2ccccc2)cc(-c2ccc(S(=O)(=O)NNCCCN3CCOCC3)cc2)c1N CHEMBL231614 pIC50 1000.0 nM
CN(C)CCCNNS(=O)(=O)c1ccc(-c2cc(-c3ccccc3)cc(C(N)=O)c2N)cc1 CHEMBL231512 pIC50 1000.0 nM
NC(=O)c1cc(-c2ccccc2)cc(-c2ccc(S(N)(=O)=O)cc2)c1N CHEMBL397008 pIC50 1000.0 nM
CNc1nc2sc(-c3cccc(CNS(C)(=O)=O)c3)nc2c2c1ncn2C CHEMBL493974 IC50 1000.0 nM
Cc1cc2c(-c3ccc(S(=O)(=O)N(C)C4CCS(=O)(=O)CC4)cc3)ccnc2[nH]1 CHEMBL483166 pIC50 1000.0 nM
COc1c(Cl)cc2c([nH]c3cnccc32)c1NC(=O)c1cccnc1C CHEMBL608154 Kd 1000.0 nM
Nc1ccc(-c2cncc(OCC(N)Cc3c[nH]c4ccccc34)c2)cc1C(=O)c1ccccc1F CHEMBL1994361 pKi 1000.0 nM
Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12 CHEMBL1682346 pKi 1000.0 nM
c1ccc(Cn2nnc(-c3ccc4[nH]ncc4c3)c2C2CC2)cc1 CHEMBL1975418 pKi 1000.0 nM
N#Cc1c[nH]c2nc(N)nc(N[C@@H]3CC[C@@H](O)[C@H]3O)c12 CHEMBL4096327 Ki 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(Cc4ccccc4)nc3C2=O)COc2ccccc21 CHEMBL4088216 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3c(nn(Cc4ccccc4)c3Br)C2=O)COc2ccccc21 CHEMBL4549667 pIC50 1000.0 nM
CN1C(=O)[C@@H](N2CCc3cn(CC4CCS(=O)(=O)CC4)nc3C2=O)COc2ccccc21 CHEMBL4097778 pIC50 1000.0 nM