O=C1/C(=C\c2ccccc2O)Oc2cc(O)ccc21 CHEMBL3979616 Ki 6.0 nM
COc1cc(/C=C2/SC(=S)NC2=O)ccc1OCc1ccc(C)cc1 CHEMBL3893332 Ki 22.0 nM
CCc1ccc(OCCCOc2ccc(/C=C3/SC(=O)NC3=O)cc2)cc1 CHEMBL3970270 Ki 29.0 nM
CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)c1ccccn1 CHEMBL121 Ki 31.0 nM
COc1cc(/C=C2/SC(=S)NC2=O)ccc1OCc1ccccc1 CHEMBL230515 Ki 33.0 nM
O=C1NC(=O)/C(=C\c2ccc(OCCOc3ccccc3Cl)cc2)S1 CHEMBL3890124 Ki 36.0 nM
O=C1NC(=O)/C(=C/c2cccc(Br)c2)S1 CHEMBL496587 Ki 37.0 nM
CN(C)c1ccc(/C=C2/Oc3cc(O)ccc3C2=O)cc1 CHEMBL3948168 Ki 39.0 nM
O=C1NC(=S)S/C1=C/c1ccc(OCc2ccc(F)cc2)c(Cl)c1 CHEMBL3959175 Ki 40.0 nM
O=C1NC(=S)S/C1=C\c1cccc(Br)c1 CHEMBL2348829 Ki 46.0 nM
CN(C)c1ccc(/C=C2/Oc3ccccc3C2=O)cc1 CHEMBL3909388 Ki 52.0 nM
O=C1NC(=O)/C(=C\c2ccc(OCCCOc3ccccc3Cl)cc2)S1 CHEMBL3924991 Ki 60.0 nM
COc1cc(/C=C2\SC(=S)NC2=O)ccc1O CHEMBL255822 Ki 74.0 nM
CC(C)(C)c1cc(C=C(C#N)C#N)cc(Br)c1O CHEMBL2218926 Ki 77.0 nM
N#CC(C#N)=Cc1ccc(O)cc1 CHEMBL305695 Ki 78.0 nM
O=C1NC(=S)S/C1=C\c1ccc(O)c(Br)c1 CHEMBL2018126 Ki 84.0 nM
COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(O)c(OC)c2)ccc1O CHEMBL140 Ki 101.0 nM
O=C1NC(=S)S/C1=C\c1cc(Br)c(Cl)cc1Br CHEMBL3956710 Ki 125.0 nM
O=c1c(O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12 CHEMBL150 Ki 132.0 nM
O=C1NC(=S)S/C1=C\c1ccc(Br)cc1 CHEMBL224467 Ki 136.0 nM
O=C1NC(=O)/C(=C/c2cccc3nccnc23)S1 CHEMBL3976274 Ki 139.0 nM
O=C1NC(=O)/C(=C/c2cc(Br)c(O)c(Br)c2)S1 CHEMBL3967845 Ki 141.0 nM
O=C1NC(=S)S/C1=C\c1cccc(C(F)(F)F)c1 CHEMBL3891346 Ki 141.0 nM
COc1cccc2c1OC(C(=O)C1=C(O)C(=O)N(c3nc(C)c(C)s3)C1c1ccco1)C2 CHEMBL3982310 Ki 141.0 nM
O=S(=O)(O)Oc1cc(O)cc(/C=C/c2ccc(O)cc2)c1 CHEMBL1208633 Ki 144.0 nM
COc1ccc2c(C[C@@H]3NC(=O)[C@@H]4CCCN4C3=O)c(CC=C(C)C)[nH]c2c1 CHEMBL289159 Ki 145.0 nM
c1ccc(C2CC2NC2CCNCC2)cc1 CHEMBL3945250 Ki 148.0 nM
O=C1NC(=O)/C(=C/c2ccc(O)c(Br)c2)S1 CHEMBL3927255 Ki 165.0 nM
COc1cc(/C=C2\SC(=S)NC2=O)cc(OC)c1O CHEMBL3930279 Ki 191.0 nM
CN1C(=O)/C(=C/c2ccc(Cl)cc2)SC1=S CHEMBL380899 Ki 213.0 nM
O=C1NC(=O)C(Cc2ccc3c(c2)OC(F)(F)O3)S1 CHEMBL1823804 Ki 224.0 nM
O=C1NC(=S)S/C1=C\c1ccncc1 CHEMBL3938874 Ki 255.0 nM
O=C1NC(=O)/C(=C/c2cccc(C(F)(F)F)c2)S1 CHEMBL183906 Ki 297.0 nM
CC(C)(C)c1cc(CC2SC(=O)N=C2O)cc(C(C)(C)C)c1O CHEMBL602048 Ki 315.0 nM
CC(=O)NC1=NC(=O)/C(=C\c2ccc(OCc3cccc(F)c3)c(Cl)c2)S1 CHEMBL3917957 Ki 341.0 nM
CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1 CHEMBL595 Ki 370.0 nM
NC(=S)N/N=C/c1ncccc1N CHEMBL231616 Ki 388.0 nM
Cc1cc(CC2SC(=O)NC2=O)cc(C)c1O CHEMBL1823802 Ki 409.0 nM
O=C(O)CCN1C(=O)/C(=C/c2ccccc2)SC1=S CHEMBL3967264 Ki 412.0 nM
O=c1c(-c2ccc(Oc3ccccc3)cc2)[n+]([O-])c2ccccc2n1O CHEMBL3936343 Ki 413.0 nM
O=C(/C=C1\SC(=S)NC1=O)Nc1ccccc1 CHEMBL3929569 Ki 472.0 nM
Cc1cc(C)cc(CC2SC(=O)NC2=O)c1 CHEMBL1823803 Ki 570.0 nM
O=C(/C=C1\SC(=S)NC1=O)Nc1cccc(O)c1 CHEMBL3901608 Ki 583.0 nM
O=C1NC(=O)C(Cc2ccc(O)cc2)S1 CHEMBL1061 Ki 598.0 nM
CN1C(=O)/C(=C/c2ccccc2)SC1=S CHEMBL500110 Ki 646.0 nM
O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1 CHEMBL572 Ki 816.0 nM
CCCN1C(=O)S/C(=C\c2ccncc2)C1=O CHEMBL3928502 Ki 831.0 nM
O=C1NC(=O)/C(=C\c2cccc(Br)c2)S1 CHEMBL1823807 IC50 860.0 nM
O=C1NC(=O)/C(=C/c2ccncc2)S1 CHEMBL3911800 Ki 952.0 nM