COc1cccc(CN2CCn3c2nc(=O)c2c3CCN(Cc3ccccc3)C2)c1 CHEMBL5170429 EC50 100.0 nM
COc1ccccc1CN1CCn2c1nc(=O)c1c2CCN(Cc2ccccc2)C1 CHEMBL5176506 EC50 110.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccccc1 CHEMBL5194447 EC50 120.0 nM
N#Cc1cccc(CN2CCC3=C(C2)C(=O)N(Cc2ccc(C(F)(F)F)cc2)C2=NCCN23)c1 CHEMBL5287429 EC50 120.0 nM
N#Cc1cccc(CN2CCC3=C(C2)C(=O)N(Cc2ccc(Cl)cc2)C2=NCCN23)c1 CHEMBL5290620 EC50 120.0 nM
Cc1cccc(CN2CCc3c(c(=O)n(Cc4ccc(C(F)(F)F)cc4)c(=O)n3CCCN)C2)c1 CHEMBL5283010 EC50 120.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2CC1CCCCC1 CHEMBL5173519 EC50 130.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccc(F)cc1 CHEMBL5180553 EC50 130.0 nM
Cn1c2c(c(=O)n(Cc3ccc(Cl)cc3)c1=O)CN(Cc1cccc(C#N)c1)CC2 CHEMBL5275131 EC50 135.0 nM
N#Cc1cccc(CN2CCc3ncn(Cc4ccc(Cl)cc4)c(=O)c3C2)c1 CHEMBL5426567 EC50 140.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccc(F)cc1F CHEMBL5205960 EC50 160.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccc(F)c(Br)c1 CHEMBL5191392 Kd 180.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccccc1Cl CHEMBL5197418 EC50 190.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccc(Br)c(F)c1 CHEMBL5196310 EC50 210.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1cccc(F)c1 CHEMBL5193179 EC50 260.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1cccc(Cl)c1 CHEMBL5185111 EC50 280.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccc(C(F)(F)F)cc1 CHEMBL5190079 EC50 290.0 nM
Cc1ccccc1CN1CCn2c1nc(=O)c1c2CCN(Cc2ccccc2)C1 CHEMBL5196543 EC50 300.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccc(Cl)cc1 CHEMBL5170508 EC50 300.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccc(F)c(F)c1 CHEMBL5172282 EC50 300.0 nM
Cc1ccccc1CN1CCn2c1nc(=O)c1c2CCN(Cc2ccc(F)c(F)c2)C1 CHEMBL5176285 EC50 320.0 nM
Cc1ccc(CN2CCn3c2nc(=O)c2c3CCN(Cc3ccccc3)C2)cc1 CHEMBL5206788 EC50 320.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccc2ccccc2c1 CHEMBL5193731 EC50 360.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1cccc(Br)c1 CHEMBL5195731 EC50 360.0 nM
C#Cc1oc2ccc3ccccc3c2c1CC(=O)Oc1ccc(-c2nnco2)cc1 CHEMBL4466041 IC50 390.0 nM
Cc1cccc(CN2CCn3c2nc(=O)c2c3CCN(Cc3ccccc3)C2)c1 CHEMBL5181406 EC50 390.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccc(Br)cc1 CHEMBL5191962 EC50 400.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2CCc1ccccc1 CHEMBL5206329 EC50 420.0 nM
O=c1nc2n(c3c1CN(Cc1ccccc1)CC3)CCN2Cc1ccccc1F CHEMBL5179264 EC50 440.0 nM
CCCCC/C=C/C(=O)N[C@@H](Cc1cc(F)cc(F)c1)C(=O)N[C@@H]1C(=O)C2CCC[C@H]2C(=O)N2CC[C@H](C)C[C@H]2C(=O)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)O[C@H]1C CHEMBL5401730 EC50 440.0 nM
CC(C)CCN1CCn2c1nc(=O)c1c2CCN(Cc2ccccc2)C1 CHEMBL5172475 EC50 450.0 nM
Cc1ccccc1CN1CCn2c1nc(=O)c1c2C(F)(F)CN(Cc2ccccc2)C1 CHEMBL5174896 EC50 500.0 nM
COc1ccc(CN2CCn3c2nc(=O)c2c3CCN(Cc3ccccc3)C2)cc1 CHEMBL5183001 EC50 500.0 nM
Cc1cccc(CN2CCc3c(c(=O)nc4n3CCN4Cc3ccccc3C)C2)c1 CHEMBL5199237 EC50 510.0 nM
Cc1ccccc1CN1CCn2c1nc(=O)c1c2CCN(Cc2cccc(C#N)c2)C1 CHEMBL5185632 EC50 580.0 nM
Cc1ccc(CN2CCc3c(c(=O)nc4n3CCN4Cc3ccccc3C)C2)cc1 CHEMBL5170872 EC50 640.0 nM
Cc1ccccc1CN1CCn2c1nc(=O)c1c2CCN(Cc2ccc(F)cc2)C1 CHEMBL5194951 EC50 640.0 nM
Cc1ccccc1CN1CCn2c1nc(=O)c1c2CCN(Cc2ccccc2C#N)C1 CHEMBL5188070 EC50 660.0 nM
C#Cc1cccc(CN2CCC3=C(C2)C(=O)N(Cc2ccc(C)cc2)C2=NCCN23)c1 CHEMBL5290082 EC50 800.0 nM
Cc1ccccc1CN1CCn2c1nc(=O)c1c2CCN(Cc2ccc(F)cc2F)C1 CHEMBL5181638 EC50 980.0 nM
Cc1ccccc1CN1C(=O)C2=C(CCN(Cc3ccccc3)C2)N2CCN=C12 CHEMBL4297310 EC50 1000.0 nM